Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | acetylcholinesterase | 0.0297 | 0.7808 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0297 | 0.7808 | 0.7808 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0462 | 0.0462 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0353 | 0.0353 |
Loa Loa (eye worm) | hypothetical protein | 0.0297 | 0.7808 | 0.7808 |
Brugia malayi | Carboxylesterase family protein | 0.005 | 0.0462 | 0.0462 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.005 | 0.0462 | 0.0146 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.005 | 0.0462 | 0.0146 |
Brugia malayi | Carboxylesterase family protein | 0.005 | 0.0462 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.0297 | 0.7808 | 0.7808 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0371 | 1 | 0.5 |
Onchocerca volvulus | 0.005 | 0.0462 | 0.5 | |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.005 | 0.0462 | 0.0592 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0462 | 0.0462 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0297 | 0.7808 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0353 | 0.0452 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0371 | 1 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.005 | 0.0462 | 0.0592 |
Schistosoma mansoni | gliotactin | 0.005 | 0.0462 | 0.0592 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.005 | 0.0462 | 0.5 |
Onchocerca volvulus | 0.005 | 0.0462 | 0.5 | |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.005 | 0.0462 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.005 | 0.0462 | 0.5 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.005 | 0.0462 | 0.0146 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0297 | 0.7808 | 0.7808 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.005 | 0.0462 | 0.0592 |
Brugia malayi | Carboxylesterase family protein | 0.005 | 0.0462 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0462 | 0.0462 |
Brugia malayi | Carboxylesterase family protein | 0.005 | 0.0462 | 0.0462 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.005 | 0.0462 | 0.0592 |
Loa Loa (eye worm) | carboxylesterase | 0.005 | 0.0462 | 0.0462 |
Echinococcus granulosus | BC026374 protein S09 family | 0.005 | 0.0462 | 0.0146 |
Onchocerca volvulus | 0.005 | 0.0462 | 0.5 | |
Echinococcus granulosus | para nitrobenzyl esterase | 0.005 | 0.0462 | 0.0146 |
Schistosoma mansoni | acetylcholinesterase | 0.005 | 0.0462 | 0.0592 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.005 | 0.0462 | 0.0146 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0051 | 0.0478 | 0.0478 |
Onchocerca volvulus | 0.005 | 0.0462 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0462 | 0.0462 |
Echinococcus granulosus | neuroligin | 0.005 | 0.0462 | 0.0146 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0353 | 0.0452 |
Brugia malayi | Carboxylesterase family protein | 0.0297 | 0.7808 | 0.7808 |
Echinococcus multilocularis | neuroligin | 0.005 | 0.0462 | 0.0146 |
Echinococcus granulosus | acetylcholinesterase | 0.0297 | 0.7808 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.005 | 0.0462 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.005 | 0.0462 | 0.0462 |
Brugia malayi | hypothetical protein | 0.005 | 0.0462 | 0.0462 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0462 | 0.0462 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0051 | 0.0478 | 0.0478 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.005 | 0.0462 | 0.5 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0371 | 1 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0297 | 0.7808 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0297 | 0.7808 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0297 | 0.7808 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0297 | 0.7808 | 1 |
Onchocerca volvulus | 0.005 | 0.0462 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0462 | 0.0462 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0353 | 0.0353 |
Brugia malayi | Carboxylesterase family protein | 0.0297 | 0.7808 | 0.7808 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0353 | 0.0452 |
Loa Loa (eye worm) | hypothetical protein | 0.0189 | 0.4607 | 0.4607 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0051 | 0.0478 | 0.0478 |
Loa Loa (eye worm) | hypothetical protein | 0.005 | 0.0462 | 0.0462 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.005 | 0.0462 | 0.0592 |
Loa Loa (eye worm) | hypothetical protein | 0.0051 | 0.0478 | 0.0478 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.005 | 0.0462 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0371 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.