Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.015 | 0.8973 | 0.8973 |
Loa Loa (eye worm) | carboxylesterase | 0.015 | 0.8973 | 0.9428 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0165 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.015 | 0.8973 | 0.8973 |
Brugia malayi | Carboxylesterase family protein | 0.015 | 0.8973 | 0.9428 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0053 | 0.1978 | 0.2079 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0025 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0775 | 0.0775 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0775 | 0.0814 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0053 | 0.1978 | 0.2079 |
Echinococcus multilocularis | acetylcholinesterase | 0.015 | 0.8973 | 0.8973 |
Brugia malayi | ecdysteroid receptor | 0.0158 | 0.9517 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.015 | 0.8973 | 0.8973 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0025 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0025 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.015 | 0.8973 | 0.9428 |
Echinococcus granulosus | acetylcholinesterase | 0.015 | 0.8973 | 0.8973 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.8973 | 0.9428 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0025 | 0 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.015 | 0.8973 | 0.9428 |
Loa Loa (eye worm) | hypothetical protein | 0.0158 | 0.9517 | 1 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0158 | 0.9517 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.015 | 0.8973 | 0.8973 |
Echinococcus multilocularis | geminin | 0.0165 | 1 | 1 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0053 | 0.1978 | 0.2079 |
Echinococcus multilocularis | acetylcholinesterase | 0.015 | 0.8973 | 0.8973 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0025 | 0 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0025 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.015 | 0.8973 | 0.9428 |
Loa Loa (eye worm) | hypothetical protein | 0.0053 | 0.1978 | 0.2079 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0036 | 0.0775 | 0.0814 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.