Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | glutamate receptor NMDA | 0.0155 | 0.0238 | 0.0238 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0169 | 0.0296 | 0.0296 |
Echinococcus granulosus | neuroligin | 0.0448 | 0.1386 | 0.1386 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0448 | 0.1386 | 1 |
Echinococcus multilocularis | neuroligin | 0.0448 | 0.1386 | 0.1386 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0448 | 0.1386 | 0.1386 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.2654 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0448 | 0.1386 | 0.1191 |
Loa Loa (eye worm) | hypothetical protein | 0.0448 | 0.1386 | 0.1191 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0448 | 0.1386 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.2654 | 1 | 1 |
Onchocerca volvulus | 0.0448 | 0.1386 | 0.5 | |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0448 | 0.1386 | 0.1386 |
Plasmodium vivax | glutathione reductase, putative | 0.015 | 0.0221 | 0.5 |
Echinococcus granulosus | glutamate NMDA receptor subunit | 0.0187 | 0.0364 | 0.0364 |
Brugia malayi | Carboxylesterase family protein | 0.0448 | 0.1386 | 0.1191 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0169 | 0.0296 | 0.0296 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.015 | 0.0221 | 0.5 |
Echinococcus granulosus | carboxylesterase 5A | 0.2654 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.2654 | 1 | 1 |
Plasmodium vivax | thioredoxin reductase, putative | 0.015 | 0.0221 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0448 | 0.1386 | 0.1191 |
Brugia malayi | Carboxylesterase family protein | 0.0448 | 0.1386 | 0.1191 |
Onchocerca volvulus | 0.0448 | 0.1386 | 0.5 | |
Onchocerca volvulus | 0.0448 | 0.1386 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0448 | 0.1386 | 0.1191 |
Echinococcus multilocularis | carboxylesterase 5A | 0.2654 | 1 | 1 |
Echinococcus granulosus | nmda type glutamate receptor | 0.0184 | 0.0352 | 0.0352 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0448 | 0.1386 | 0.1386 |
Echinococcus multilocularis | glutamate (NMDA) receptor subunit | 0.0187 | 0.0364 | 0.0364 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.2654 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0448 | 0.1386 | 0.1191 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0187 | 0.0364 | 0.0147 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0448 | 0.1386 | 0.1386 |
Loa Loa (eye worm) | hypothetical protein | 0.0448 | 0.1386 | 0.1191 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0448 | 0.1386 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.2654 | 1 | 1 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0448 | 0.1386 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.2654 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0448 | 0.1386 | 0.1191 |
Loa Loa (eye worm) | hypothetical protein | 0.0448 | 0.1386 | 0.1191 |
Brugia malayi | hypothetical protein | 0.0448 | 0.1386 | 0.1191 |
Trypanosoma brucei | trypanothione reductase | 0.015 | 0.0221 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0448 | 0.1386 | 0.1191 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.015 | 0.0221 | 0.0221 |
Loa Loa (eye worm) | hypothetical protein | 0.0448 | 0.1386 | 0.1191 |
Brugia malayi | Carboxylesterase family protein | 0.0448 | 0.1386 | 0.1191 |
Onchocerca volvulus | 0.0448 | 0.1386 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.2654 | 1 | 1 |
Echinococcus multilocularis | nmda type glutamate receptor | 0.0184 | 0.0352 | 0.0352 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0448 | 0.1386 | 0.1191 |
Schistosoma mansoni | glutamate receptor NMDA | 0.0248 | 0.0604 | 0.0391 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0448 | 0.1386 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0448 | 0.1386 | 0.1191 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0448 | 0.1386 | 0.1191 |
Onchocerca volvulus | 0.0448 | 0.1386 | 0.5 | |
Loa Loa (eye worm) | carboxylesterase | 0.0448 | 0.1386 | 0.1191 |
Brugia malayi | Carboxylesterase family protein | 0.2654 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.2654 | 1 | 1 |
Schistosoma mansoni | acetylcholinesterase | 0.0448 | 0.1386 | 0.1191 |
Leishmania major | trypanothione reductase | 0.015 | 0.0221 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0448 | 0.1386 | 0.1191 |
Toxoplasma gondii | thioredoxin reductase | 0.015 | 0.0221 | 0.5 |
Schistosoma mansoni | gliotactin | 0.0448 | 0.1386 | 0.1191 |
Plasmodium falciparum | glutathione reductase | 0.015 | 0.0221 | 0.5 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0448 | 0.1386 | 0.1386 |
Echinococcus granulosus | glutamate receptor NMDA | 0.0155 | 0.0238 | 0.0238 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.015 | 0.0221 | 0.0221 |
Plasmodium falciparum | thioredoxin reductase | 0.015 | 0.0221 | 0.5 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0448 | 0.1386 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.2654 | 1 | 1 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0448 | 0.1386 | 0.1386 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.