Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.005 | 0.0004 | 0.0004 |
Echinococcus granulosus | carboxylesterase 5A | 0.048 | 0.5446 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.0612 | 0.1017 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0081 | 0.0395 | 0.5 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0081 | 0.0395 | 0.0654 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.0612 | 0.0612 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0081 | 0.0395 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0081 | 0.0395 | 0.0719 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0098 | 0.0612 | 0.1118 |
Echinococcus multilocularis | carboxylesterase 5A | 0.048 | 0.5446 | 0.5446 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.0164 | 0.0164 |
Brugia malayi | Carboxylesterase family protein | 0.0081 | 0.0395 | 0.0719 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.0612 | 0.1017 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.0164 | 0.0294 |
Brugia malayi | Niemann-Pick C1 protein precursor | 0.0102 | 0.0659 | 0.1203 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0098 | 0.0612 | 0.1118 |
Brugia malayi | Carboxylesterase family protein | 0.0081 | 0.0395 | 0.0719 |
Brugia malayi | Carboxylesterase family protein | 0.048 | 0.5446 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.048 | 0.5446 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0108 | 0.0742 | 0.1356 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0164 | 0.0267 |
Brugia malayi | Carboxylesterase family protein | 0.048 | 0.5446 | 1 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0146 | 0.1213 | 0.2221 |
Echinococcus multilocularis | acetylcholinesterase | 0.048 | 0.5446 | 0.5446 |
Echinococcus granulosus | neuroligin | 0.0081 | 0.0395 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0395 | 0.0719 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0081 | 0.0395 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0306 | 0.3248 | 0.5961 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0164 | 0.0267 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0146 | 0.1213 | 0.1213 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.0612 | 0.1118 |
Echinococcus multilocularis | neuroligin | 0.0081 | 0.0395 | 0.0395 |
Brugia malayi | Carboxylesterase family protein | 0.0081 | 0.0395 | 0.0719 |
Onchocerca volvulus | 0.0306 | 0.3248 | 1 | |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0081 | 0.0395 | 0.0654 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0395 | 0.0719 |
Brugia malayi | RNA binding protein | 0.0063 | 0.0164 | 0.0294 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.0046 | 0.0078 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0081 | 0.0395 | 0.5 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0159 | 0.1378 | 0.2525 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0081 | 0.0395 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0108 | 0.0742 | 0.1234 |
Echinococcus granulosus | Niemann Pick C1 protein | 0.0102 | 0.0659 | 0.1203 |
Brugia malayi | hypothetical protein | 0.0081 | 0.0395 | 0.0719 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1497 | 0.2496 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0395 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0395 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0159 | 0.1378 | 0.2525 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0395 | 0.0719 |
Schistosoma mansoni | niemann-pick C1 (NPC1) | 0.0103 | 0.0679 | 0.1128 |
Loa Loa (eye worm) | hypothetical protein | 0.0102 | 0.0659 | 0.1203 |
Echinococcus multilocularis | acetylcholinesterase | 0.048 | 0.5446 | 0.5446 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0081 | 0.0395 | 0.0654 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0098 | 0.0612 | 0.1118 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.0164 | 0.0294 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0081 | 0.0395 | 0.0654 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0081 | 0.0395 | 0.0395 |
Loa Loa (eye worm) | hypothetical protein | 0.048 | 0.5446 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.048 | 0.5446 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.048 | 0.5446 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.048 | 0.5446 | 0.9096 |
Echinococcus granulosus | acetylcholinesterase | 0.048 | 0.5446 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0098 | 0.0612 | 0.0612 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.1497 | 0.2496 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.0164 | 0.0294 |
Schistosoma mansoni | acetylcholinesterase | 0.0081 | 0.0395 | 0.0654 |
Echinococcus granulosus | expressed conserved protein | 0.0096 | 0.058 | 0.106 |
Echinococcus granulosus | acetylcholinesterase | 0.048 | 0.5446 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0081 | 0.0395 | 0.0395 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0395 | 0.0719 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0164 | 0.0267 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.005 | 0.0004 | 0.0004 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0081 | 0.0395 | 0.0719 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0081 | 0.0395 | 0.0654 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.0395 | 0.0719 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.0164 | 0.0294 |
Echinococcus multilocularis | Niemann Pick C1 protein | 0.0102 | 0.0659 | 0.0659 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0164 | 0.0267 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0098 | 0.0612 | 0.1017 |
Echinococcus multilocularis | expressed conserved protein | 0.0096 | 0.058 | 0.058 |
Echinococcus granulosus | geminin | 0.0168 | 0.1497 | 0.2744 |
Entamoeba histolytica | Niemann-Pick C1 protein, putative | 0.0102 | 0.0659 | 0.5 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0081 | 0.0395 | 0.0719 |
Loa Loa (eye worm) | carboxylesterase | 0.0081 | 0.0395 | 0.0719 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0523 | 0.5986 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0081 | 0.0395 | 0.5 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0081 | 0.0395 | 0.0395 |
Brugia malayi | hypothetical protein | 0.0306 | 0.3248 | 0.5961 |
Brugia malayi | Carboxylesterase family protein | 0.0081 | 0.0395 | 0.0719 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0159 | 0.1378 | 0.2525 |
Echinococcus multilocularis | geminin | 0.0168 | 0.1497 | 0.1497 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.0164 | 0.0294 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.0164 | 0.0294 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.0164 | 0.0267 |
Echinococcus multilocularis | GPCR, family 2 | 0.005 | 0.0004 | 0.0004 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0081 | 0.0395 | 0.0719 |
Loa Loa (eye worm) | hypothetical protein | 0.0108 | 0.0742 | 0.1356 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0159 | 0.1378 | 0.2525 |
Schistosoma mansoni | gliotactin | 0.0081 | 0.0395 | 0.0654 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.