Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0072 | 0.0447 | 0.5 |
Onchocerca volvulus | 0.0072 | 0.0447 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0447 | 0.0447 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0072 | 0.0447 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0447 | 0.0447 |
Echinococcus granulosus | geminin | 0.0205 | 0.4044 | 0.4044 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0447 | 0.0447 |
Brugia malayi | Carboxylesterase family protein | 0.0072 | 0.0447 | 0.0447 |
Echinococcus granulosus | acetylcholinesterase | 0.0425 | 1 | 1 |
Schistosoma mansoni | gliotactin | 0.0072 | 0.0447 | 0.0447 |
Echinococcus multilocularis | geminin | 0.0205 | 0.4044 | 0.4044 |
Onchocerca volvulus | 0.0072 | 0.0447 | 0.5 | |
Brugia malayi | Carboxylesterase family protein | 0.0072 | 0.0447 | 0.0447 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0425 | 1 | 1 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0072 | 0.0447 | 0.0447 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0072 | 0.0447 | 0.0447 |
Loa Loa (eye worm) | carboxylesterase | 0.0072 | 0.0447 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0425 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0425 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0425 | 1 | 1 |
Onchocerca volvulus | 0.0072 | 0.0447 | 0.5 | |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0447 | 0.0447 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0072 | 0.0447 | 0.0447 |
Onchocerca volvulus | 0.0072 | 0.0447 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.0425 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0072 | 0.0447 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0072 | 0.0447 | 0.0447 |
Schistosoma mansoni | acetylcholinesterase | 0.0072 | 0.0447 | 0.0447 |
Brugia malayi | hypothetical protein | 0.0072 | 0.0447 | 0.0447 |
Loa Loa (eye worm) | carboxylesterase | 0.0425 | 1 | 1 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0072 | 0.0447 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.4044 | 0.4044 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0447 | 0.0447 |
Brugia malayi | Carboxylesterase family protein | 0.0072 | 0.0447 | 0.0447 |
Onchocerca volvulus | 0.0072 | 0.0447 | 0.5 | |
Echinococcus granulosus | acetylcholinesterase | 0.0425 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0072 | 0.0447 | 0.0447 |
Schistosoma mansoni | memapsin-2 (A01 family) | 0.0421 | 0.9897 | 0.9897 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0072 | 0.0447 | 0.5 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0072 | 0.0447 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0447 | 0.0447 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0072 | 0.0447 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0072 | 0.0447 | 0.0447 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0072 | 0.0447 | 0.0447 |
Echinococcus multilocularis | neuroligin | 0.0072 | 0.0447 | 0.0447 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0072 | 0.0447 | 0.0447 |
Echinococcus granulosus | carboxylesterase 5A | 0.0425 | 1 | 1 |
Echinococcus granulosus | neuroligin | 0.0072 | 0.0447 | 0.0447 |
Loa Loa (eye worm) | hypothetical protein | 0.0425 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0072 | 0.0447 | 0.0447 |
Echinococcus multilocularis | acetylcholinesterase | 0.0425 | 1 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0072 | 0.0447 | 0.5 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0072 | 0.0447 | 0.0447 |
Schistosoma mansoni | hypothetical protein | 0.0205 | 0.4044 | 0.4044 |
Loa Loa (eye worm) | carboxylesterase | 0.0072 | 0.0447 | 0.0447 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0072 | 0.0447 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.