Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | glutathione reductase | 0.004 | 0.1689 | 0.1592 |
Leishmania major | hypothetical protein, conserved | 0.0027 | 0.0885 | 0.0779 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0015 | 0.0192 | 0.0192 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.002 | 0.0478 | 0.0096 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0015 | 0.0192 | 0.0192 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.2891 | 0.4287 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0014 | 0.0115 | 0.0015 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.5036 | 0.5036 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0026 | 0.0844 | 0.0844 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0034 | 0.1342 | 0.1242 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0101 | 0.5388 | 1 |
Trypanosoma brucei | ISWI complex protein | 0.0015 | 0.02 | 0.0086 |
Echinococcus granulosus | zinc finger protein | 0.0026 | 0.0877 | 0.0877 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0066 | 0.3289 | 0.3289 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0305 | 0.0305 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0039 | 0.1632 | 0.1632 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0129 | 0.7069 | 0.7069 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0091 | 0.4775 | 0.8837 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0039 | 0.1632 | 1 |
Echinococcus granulosus | methyl CpG binding domain protein 2 | 0.0017 | 0.0305 | 0.0305 |
Trichomonas vaginalis | rotamase, putative | 0.0034 | 0.1342 | 0.6667 |
Brugia malayi | hypothetical protein | 0.0027 | 0.0885 | 0.0779 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0083 | 0.4316 | 0.425 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0039 | 0.1632 | 0.1632 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0121 | 0.6591 | 1 |
Echinococcus granulosus | carbonic anhydrase II | 0.0178 | 1 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0015 | 0.0192 | 0.0192 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0083 | 0.4316 | 0.425 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0478 | 0.056 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0033 | 0.1294 | 0.1192 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.004 | 0.1689 | 0.2985 |
Echinococcus multilocularis | cpg binding protein | 0.0066 | 0.3276 | 0.3276 |
Onchocerca volvulus | 0.0061 | 0.2952 | 0.5 | |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0885 | 0.1834 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0478 | 0.2392 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.2891 | 0.2891 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.194 | 0.1617 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0019 | 0.0416 | 0.0416 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0316 | 0.0204 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0178 | 1 | 1 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.0178 | 1 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0178 | 1 | 1 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0178 | 1 | 1 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0478 | 0.0478 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0036 | 0.144 | 0.144 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.1632 | 0.1535 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.004 | 0.1721 | 0.1721 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0139 | 0.7657 | 0.7657 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0018 | 0.0385 | 0.0385 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0044 | 0.1957 | 0.2845 |
Loa Loa (eye worm) | glutathione reductase | 0.004 | 0.1689 | 0.1356 |
Echinococcus granulosus | cpg binding protein | 0.0066 | 0.3276 | 0.3276 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.0478 | 0.2437 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.02 | 0.0086 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.052 | 0.052 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0083 | 0.4316 | 0.4088 |
Leishmania major | hypothetical protein, conserved | 0.0015 | 0.02 | 0.0086 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0885 | 0.0779 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0014 | 0.0115 | 0.0015 |
Echinococcus multilocularis | geminin | 0.0173 | 0.9741 | 0.9741 |
Schistosoma mansoni | cpg binding protein | 0.0061 | 0.2952 | 0.2952 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0039 | 0.1632 | 0.2343 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0885 | 0.052 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0091 | 0.4775 | 0.8468 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.1294 | 0.1192 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0044 | 0.1957 | 1 |
Schistosoma mansoni | zinc finger protein | 0.0026 | 0.0877 | 0.0877 |
Mycobacterium tuberculosis | Probable reductase | 0.0091 | 0.4775 | 0.8837 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0095 | 0.5036 | 0.4837 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0385 | 0.0385 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.4316 | 0.4088 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0027 | 0.0885 | 0.4182 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0478 | 0.0478 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0066 | 0.3289 | 0.3289 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.4316 | 0.4088 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.2891 | 0.2808 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0478 | 0.1982 |
Schistosoma mansoni | cpg binding protein | 0.0066 | 0.3276 | 0.3276 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0095 | 0.5036 | 0.5036 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.2891 | 0.2891 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0478 | 0.1307 |
Echinococcus multilocularis | carbonic anhydrase | 0.0083 | 0.4316 | 0.4316 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0039 | 0.1604 | 1 |
Brugia malayi | acetyltransferase, GNAT family protein | 0.0145 | 0.8041 | 0.8019 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.2891 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.5036 | 0.5036 |
Echinococcus granulosus | carbonic anhydrase | 0.0083 | 0.4316 | 0.4316 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.0178 | 1 | 1 |
Brugia malayi | PHD-finger family protein | 0.0032 | 0.1198 | 0.1096 |
Echinococcus multilocularis | carbonic anhydrase II | 0.0178 | 1 | 1 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0095 | 0.5036 | 0.4978 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.2891 | 0.5264 |
Echinococcus granulosus | geminin | 0.0173 | 0.9741 | 0.9741 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.9741 | 0.9741 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0.1604 | 0.9752 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.1604 | 0.3544 |
Schistosoma mansoni | bromodomain containing protein | 0.007 | 0.3504 | 0.3504 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.1632 | 0.1632 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0033 | 0.1294 | 0.1192 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0145 | 0.8041 | 0.8041 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0027 | 0.0885 | 0.1834 |
Plasmodium falciparum | carbonic anhydrase | 0.0083 | 0.4316 | 1 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0091 | 0.4775 | 0.8837 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0083 | 0.4316 | 0.425 |
Loa Loa (eye worm) | inositol-1 | 0.0039 | 0.1632 | 0.1297 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0083 | 0.4316 | 0.425 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0091 | 0.4775 | 0.8837 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.0178 | 1 | 1 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0039 | 0.1632 | 0.8239 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0044 | 0.1957 | 0.2845 |
Plasmodium vivax | glutathione reductase, putative | 0.004 | 0.1689 | 0.8545 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0044 | 0.1957 | 0.1957 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.2264 | 0.1954 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.002 | 0.0516 | 0.0406 |
Trypanosoma brucei | trypanothione reductase | 0.004 | 0.1689 | 0.1592 |
Plasmodium falciparum | glutathione reductase | 0.004 | 0.1689 | 0.3747 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0027 | 0.0885 | 0.119 |
Loa Loa (eye worm) | thioredoxin reductase | 0.004 | 0.1689 | 0.1356 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0014 | 0.0115 | 0.0115 |
Trichomonas vaginalis | rotamase, putative | 0.0033 | 0.1294 | 0.6404 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.1586 | 0.1249 |
Loa Loa (eye worm) | hypothetical protein | 0.0083 | 0.4316 | 0.4088 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0091 | 0.4775 | 0.8837 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0033 | 0.1294 | 0.1192 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.2891 | 0.2891 |
Brugia malayi | CXXC zinc finger family protein | 0.0061 | 0.2952 | 0.287 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.1632 | 0.1535 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0478 | 0.197 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.0178 | 1 | 1 |
Echinococcus multilocularis | zinc finger protein | 0.0026 | 0.0877 | 0.0877 |
Schistosoma mansoni | cpg binding protein | 0.0066 | 0.3276 | 0.3276 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0478 | 0.0367 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0145 | 0.8041 | 0.8041 |
Brugia malayi | Bromodomain containing protein | 0.0082 | 0.4209 | 0.4141 |
Loa Loa (eye worm) | acetyltransferase | 0.0145 | 0.8041 | 0.7963 |
Toxoplasma gondii | hypothetical protein | 0.0083 | 0.4316 | 0.6487 |
Echinococcus granulosus | carbonic anhydrase | 0.0083 | 0.4316 | 0.4316 |
Schistosoma mansoni | rotamase | 0.0034 | 0.1342 | 0.1342 |
Schistosoma mansoni | methyl-cpg binding protein mbd | 0.0017 | 0.0305 | 0.0305 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.2891 | 1 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.004 | 0.1721 | 0.1721 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0014 | 0.0115 | 0.5 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0034 | 0.1342 | 0.0995 |
Brugia malayi | Thioredoxin reductase | 0.004 | 0.1689 | 0.1592 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0478 | 0.0478 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.5036 | 0.5036 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0044 | 0.1957 | 1 |
Echinococcus granulosus | expressed protein | 0.0034 | 0.1342 | 0.1342 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.1632 | 0.8239 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0021 | 0.0553 | 0.0174 |
Echinococcus multilocularis | carbonic anhydrase | 0.0083 | 0.4316 | 0.4316 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.1632 | 0.1535 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0014 | 0.0115 | 0.0115 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0026 | 0.0844 | 0.0844 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.0178 | 1 | 1 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.1632 | 0.8239 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0091 | 0.4775 | 0.8837 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0015 | 0.0192 | 0.0192 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0478 | 0.0478 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0018 | 0.0385 | 0.0385 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0027 | 0.0885 | 0.0779 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0478 | 0.1982 |
Trypanosoma cruzi | ISWI complex protein | 0.0015 | 0.02 | 0.0086 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0478 | 0.0367 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0033 | 0.1294 | 0.7067 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0101 | 0.5388 | 1 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0026 | 0.0844 | 0.0844 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.1632 | 0.1632 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0014 | 0.0115 | 0.0115 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.5036 | 0.5036 |
Echinococcus multilocularis | expressed protein | 0.0034 | 0.1342 | 0.1342 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0095 | 0.5036 | 0.5036 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0019 | 0.0416 | 0.0416 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0033 | 0.1294 | 0.182 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.052 | 0.014 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0083 | 0.4316 | 0.4316 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0027 | 0.0885 | 0.0779 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0039 | 0.1632 | 0.5466 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0035 | 0.1386 | 0.241 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0044 | 0.1957 | 1 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.1632 | 0.1535 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0018 | 0.0385 | 0.0385 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0034 | 0.1342 | 0.6667 |
Echinococcus multilocularis | carbonic anhydrase | 0.0083 | 0.4316 | 0.4316 |
Loa Loa (eye worm) | histone methyltransferase | 0.0019 | 0.0416 | 0.0032 |
Schistosoma mansoni | hypothetical protein | 0.0173 | 0.9741 | 0.9741 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0015 | 0.0192 | 0.0192 |
Brugia malayi | Bromodomain containing protein | 0.0042 | 0.1793 | 0.1698 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0039 | 0.1632 | 1 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0101 | 0.5388 | 1 |
Echinococcus multilocularis | methyl CpG binding domain protein 2 | 0.0017 | 0.0305 | 0.0305 |
Schistosoma mansoni | carbonic anhydrase | 0.0083 | 0.4316 | 0.4316 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0095 | 0.5036 | 0.5036 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0083 | 0.4316 | 0.425 |
Schistosoma mansoni | hypothetical protein | 0.0083 | 0.4316 | 0.4316 |
Plasmodium falciparum | thioredoxin reductase | 0.004 | 0.1689 | 0.3747 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0083 | 0.4316 | 0.4316 |
Leishmania major | trypanothione reductase | 0.004 | 0.1689 | 0.1592 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0101 | 0.5388 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0061 | 0.2952 | 0.267 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0036 | 0.144 | 0.144 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.2891 | 0.2891 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0478 | 0.0367 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.004 | 0.1689 | 0.1592 |
Leishmania major | carbonic anhydrase-like protein | 0.0178 | 1 | 1 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0478 | 0.0367 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0083 | 0.4316 | 0.4316 |
Schistosoma mansoni | zinc finger protein | 0.0015 | 0.02 | 0.02 |
Echinococcus granulosus | carbonic anhydrase | 0.0083 | 0.4316 | 0.4316 |
Brugia malayi | Inositol-1 | 0.0039 | 0.1632 | 0.1535 |
Plasmodium vivax | thioredoxin reductase, putative | 0.004 | 0.1689 | 0.8545 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0478 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0478 | 0.0367 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0478 | 0.0864 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.02 | 0.02 |
Toxoplasma gondii | thioredoxin reductase | 0.004 | 0.1689 | 0.2431 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.2891 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.007 | 0.3531 | 0.3272 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0478 | 0.0688 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.