Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus granulosus | tar DNA binding protein | 0.0062 | 0.838 | 0.2933 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.292 | 0.0969 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0059 | 0.7708 | 0.5 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0068 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0068 | 1 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0041 | 0.292 | 0.0969 |
Brugia malayi | TAR-binding protein | 0.0062 | 0.838 | 0.7934 |
Brugia malayi | RNA binding protein | 0.0062 | 0.838 | 0.7934 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.838 | 0.2933 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.292 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0062 | 0.838 | 0.838 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.838 | 0.2933 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.7708 | 0.5 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0062 | 0.838 | 0.7934 |
Echinococcus multilocularis | tar DNA binding protein | 0.0062 | 0.838 | 0.2933 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0038 | 0.216 | 0.7399 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0059 | 0.7708 | 0.5 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 1 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.838 | 0.2933 |
Echinococcus multilocularis | chromobox protein 1 | 0.0068 | 1 | 1 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0059 | 0.7708 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.7708 | 0.5 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 1 | 1 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0059 | 0.7708 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0062 | 0.838 | 0.838 |
Schistosoma mansoni | chromobox protein | 0.0068 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0062 | 0.838 | 0.838 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.838 | 0.2933 |
Schistosoma mansoni | chromobox protein | 0.0068 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.216 | 0.216 |
Schistosoma mansoni | tar DNA-binding protein | 0.0062 | 0.838 | 0.2933 |
Echinococcus granulosus | chromobox protein 1 | 0.0068 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.