Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | MH2 domain containing protein | 0.0128 | 0.5203 | 0.5985 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.002 | 0.0151 | 0.0178 |
Plasmodium falciparum | transporter, putative | 0.0028 | 0.0528 | 0.0592 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0028 | 0.0528 | 0.0608 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0418 | 0.2573 |
Chlamydia trachomatis | Ssodium-dependent amino acid transporter | 0.0028 | 0.0528 | 0.0592 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.002 | 0.0151 | 0.0895 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0028 | 0.0528 | 0.0695 |
Plasmodium vivax | amine transporter, putative | 0.0028 | 0.0528 | 0.0592 |
Brugia malayi | Thioredoxin reductase | 0.0051 | 0.1601 | 0.1842 |
Schistosoma mansoni | alpha glucosidase | 0.0035 | 0.0863 | 0.1189 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0028 | 0.0528 | 0.0695 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0189 | 0.8016 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0664 | 0.0895 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.002 | 0.0151 | 0.0138 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0018 | 0.0057 | 0.0061 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0151 | 0.0118 |
Plasmodium vivax | hypothetical protein, conserved | 0.0028 | 0.0528 | 0.0592 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0035 | 0.0843 | 0.1042 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0595 | 0.0793 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.0029 | 0.0595 | 0.0793 |
Schistosoma mansoni | hypothetical protein | 0.0038 | 0.0984 | 0.1367 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0863 | 0.0811 |
Schistosoma mansoni | alpha-glucosidase | 0.0136 | 0.5541 | 0.8089 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.002 | 0.0151 | 0.0138 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0097 | 0.3744 | 0.4306 |
Brugia malayi | Pre-SET motif family protein | 0.0029 | 0.0595 | 0.0684 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0057 | 0.0306 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0066 | 0.2318 | 0.2666 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0418 | 0.2573 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0863 | 0.0811 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0038 | 0.0984 | 0.1367 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0028 | 0.0528 | 0.0695 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0051 | 0.1601 | 0.2277 |
Loa Loa (eye worm) | norepinephrine transporter | 0.0164 | 0.6836 | 0.7825 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0028 | 0.0528 | 0.0608 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0051 | 0.1601 | 0.1989 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0164 | 0.6836 | 1 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0057 | 0.0306 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0116 | 0.4628 | 0.5769 |
Plasmodium vivax | SET domain protein, putative | 0.0029 | 0.0595 | 0.0675 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0028 | 0.0528 | 0.0442 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0129 | 0.5229 | 0.6115 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.103 | 0.0979 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0028 | 0.0528 | 0.0695 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0664 | 0.0764 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.103 | 0.6417 |
Trichomonas vaginalis | set domain proteins, putative | 0.0232 | 1 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.0029 | 0.0595 | 0.0793 |
Toxoplasma gondii | exonuclease III APE | 0.002 | 0.0151 | 0.0178 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0028 | 0.0528 | 0.0442 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0863 | 0.5367 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0863 | 0.0811 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0018 | 0.0057 | 0.0061 |
Trichomonas vaginalis | sucrase-isomaltase, putative | 0.0035 | 0.0863 | 0.0811 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0038 | 0.0984 | 0.1367 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.002 | 0.0151 | 0.0895 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0984 | 0.9472 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0038 | 0.0984 | 0.1367 |
Echinococcus multilocularis | neutral alpha glucosidase AB | 0.0035 | 0.0863 | 0.1189 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0028 | 0.0528 | 0.0649 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0035 | 0.0863 | 0.0993 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0863 | 0.8098 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.002 | 0.0151 | 0.0118 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0545 | 0.0719 |
Loa Loa (eye worm) | glutathione reductase | 0.0051 | 0.1601 | 0.1697 |
Brugia malayi | Inositol-1 | 0.0039 | 0.103 | 0.1185 |
Echinococcus granulosus | sodium dependent neurotransmitter transporter | 0.0028 | 0.0528 | 0.0695 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0204 | 0.8694 | 1 |
Trichomonas vaginalis | maltase-glucoamylase, putative | 0.0035 | 0.0863 | 0.0811 |
Echinococcus granulosus | neutral alpha glucosidase AB | 0.0035 | 0.0863 | 0.1189 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0664 | 0.0601 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0116 | 0.4628 | 0.5769 |
Plasmodium falciparum | glutathione reductase | 0.0051 | 0.1601 | 0.194 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0151 | 0.0138 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0028 | 0.0528 | 0.0649 |
Echinococcus granulosus | sodium:chloride dependent neurotransmitter | 0.0028 | 0.0528 | 0.0695 |
Brugia malayi | hypothetical protein | 0.0028 | 0.0528 | 0.0608 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0018 | 0.0057 | 0.0061 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.0029 | 0.0595 | 0.0793 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0039 | 0.103 | 0.1436 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0158 | 0.656 | 0.9593 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0151 | 0.0094 |
Toxoplasma gondii | hypothetical protein | 0.0028 | 0.0528 | 0.0649 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.103 | 0.6417 |
Mycobacterium tuberculosis | Probable reductase | 0.0116 | 0.4628 | 0.5769 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0116 | 0.4628 | 0.5277 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0035 | 0.0863 | 0.5367 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0863 | 0.0811 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0057 | 0.0306 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0664 | 0.0601 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.6836 | 0.7825 |
Entamoeba histolytica | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0863 | 0.8098 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0418 | 0.2573 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0051 | 0.1601 | 1 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0129 | 0.5229 | 0.652 |
Onchocerca volvulus | 0.0091 | 0.3473 | 0.3468 | |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0664 | 0.0895 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0984 | 0.9472 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0418 | 0.0313 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.0029 | 0.0595 | 0.0793 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0028 | 0.0528 | 0.0695 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0664 | 0.0895 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0595 | 0.0793 |
Plasmodium vivax | glutathione reductase, putative | 0.0051 | 0.1601 | 0.194 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.6836 | 0.7825 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0028 | 0.0528 | 0.0695 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0151 | 0.0895 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0057 | 0.0306 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.0029 | 0.0595 | 0.0793 |
Schistosoma mansoni | alpha-glucosidase | 0.0136 | 0.5541 | 0.8089 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0018 | 0.0057 | 0.0306 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0018 | 0.0057 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0528 | 0.0442 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0028 | 0.0528 | 0.0695 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0129 | 0.5229 | 0.652 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0028 | 0.0528 | 0.0695 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0097 | 0.3744 | 0.4306 |
Onchocerca volvulus | 0.0028 | 0.0528 | 0.052 | |
Onchocerca volvulus | 0.0164 | 0.6836 | 0.6833 | |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.002 | 0.0151 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0664 | 0.0895 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0528 | 0.0442 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0863 | 0.0811 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0164 | 0.6836 | 0.7863 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0028 | 0.0528 | 0.0695 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.0029 | 0.0595 | 0.0732 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0664 | 0.0895 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0418 | 0.0454 |
Brugia malayi | hypothetical protein | 0.0038 | 0.0984 | 0.1132 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.103 | 0.6417 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0057 | 0.0306 |
Trichomonas vaginalis | neutral alpha-glucosidase ab precursor, putative | 0.0035 | 0.0863 | 0.0811 |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0028 | 0.0528 | 0.0695 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0018 | 0.0057 | 0.0306 |
Brugia malayi | hypothetical protein | 0.0025 | 0.0418 | 0.0481 |
Trichomonas vaginalis | hypothetical protein | 0.0189 | 0.8016 | 0.8004 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0189 | 0.8016 | 1 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0189 | 0.8016 | 1 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0189 | 0.8016 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0028 | 0.0528 | 0.0649 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0039 | 0.103 | 0.0979 |
Echinococcus multilocularis | uncharacterized sodium dependent transporter | 0.0028 | 0.0528 | 0.0695 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0984 | 0.9472 |
Trichomonas vaginalis | ap endonuclease, putative | 0.002 | 0.0151 | 0.0094 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0189 | 0.8016 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0528 | 0.0442 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0028 | 0.0528 | 0.0695 |
Leishmania major | trypanothione reductase | 0.0051 | 0.1601 | 1 |
Trichomonas vaginalis | alpha-glucosidase, putative | 0.0035 | 0.0863 | 0.0811 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0057 | 0.0306 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.103 | 0.1436 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0039 | 0.103 | 0.1276 |
Onchocerca volvulus | 0.0028 | 0.0528 | 0.052 | |
Onchocerca volvulus | 0.0029 | 0.0595 | 0.0587 | |
Leishmania major | alpha glucosidase II subunit, putative | 0.0035 | 0.0863 | 0.5367 |
Plasmodium falciparum | thioredoxin reductase | 0.0051 | 0.1601 | 0.194 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0018 | 0.0057 | 0.0066 |
Loa Loa (eye worm) | serotonin transporter b | 0.0164 | 0.6836 | 0.7825 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0128 | 0.5203 | 0.5914 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0664 | 0.0895 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0164 | 0.6836 | 1 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0664 | 0.0764 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0418 | 0.0454 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0158 | 0.656 | 0.7503 |
Schistosoma mansoni | ap endonuclease | 0.002 | 0.0151 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0164 | 0.6836 | 0.7825 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.002 | 0.0151 | 0.0138 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0595 | 0.0519 |
Brugia malayi | Sodium:neurotransmitter symporter family protein 1, putative | 0.0028 | 0.0528 | 0.0608 |
Schistosoma mansoni | sodium/chloride dependent neurotransmitter transporter | 0.0028 | 0.0528 | 0.0695 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0018 | 0.0057 | 0.0306 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0418 | 0.0512 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0051 | 0.1601 | 0.2277 |
Trypanosoma brucei | glucosidase, putative | 0.0035 | 0.0863 | 0.5367 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.002 | 0.0151 | 0.0895 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0528 | 0.0442 |
Echinococcus granulosus | uncharacterized sodium dependent transporter | 0.0028 | 0.0528 | 0.0695 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0039 | 0.103 | 0.6417 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0418 | 0.2573 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.2318 | 0.2537 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0664 | 0.0895 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0116 | 0.4628 | 0.5769 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0189 | 0.8016 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0066 | 0.2318 | 0.3335 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0528 | 0.0442 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0128 | 0.5203 | 0.5914 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0051 | 0.1601 | 0.194 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0057 | 0.0306 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0189 | 0.8016 | 1 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0664 | 0.0895 |
Loa Loa (eye worm) | glycosyl hydrolase family 31 protein | 0.0035 | 0.0863 | 0.0834 |
Echinococcus granulosus | serotonin transporter | 0.0164 | 0.6836 | 1 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0664 | 0.0895 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0018 | 0.0057 | 0.0061 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0051 | 0.1601 | 0.1697 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0057 | 0.0306 |
Echinococcus multilocularis | serotonin transporter | 0.0164 | 0.6836 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0528 | 0.0442 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0039 | 0.103 | 0.0979 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0018 | 0.0057 | 0.0306 |
Trypanosoma brucei | trypanothione reductase | 0.0051 | 0.1601 | 1 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0129 | 0.5229 | 0.652 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0189 | 0.8016 | 1 |
Echinococcus multilocularis | lysosomal alpha glucosidase | 0.0158 | 0.656 | 0.9593 |
Schistosoma mansoni | inositol monophosphatase | 0.0039 | 0.103 | 0.1436 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.0528 | 0.0442 |
Brugia malayi | Pre-SET motif family protein | 0.0204 | 0.8694 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0097 | 0.3744 | 0.4206 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0018 | 0.0057 | 0.0306 |
Loa Loa (eye worm) | inositol-1 | 0.0039 | 0.103 | 0.103 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0039 | 0.103 | 1 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0039 | 0.103 | 0.1276 |
Plasmodium falciparum | amino acid transporter, putative | 0.0028 | 0.0528 | 0.0592 |
Brugia malayi | Glycosyl hydrolases family 31 protein | 0.0158 | 0.656 | 0.7546 |
Toxoplasma gondii | glycosyl hydrolase, family 31 protein | 0.0035 | 0.0863 | 0.1068 |
Loa Loa (eye worm) | solute carrier family 6 member 4 | 0.0164 | 0.6836 | 0.7825 |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0028 | 0.0528 | 0.0608 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0039 | 0.103 | 0.1223 |
Brugia malayi | glutathione reductase | 0.0051 | 0.1601 | 0.1842 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0057 | 0.0306 |
Echinococcus granulosus | lysosomal alpha glucosidase | 0.0158 | 0.656 | 0.9593 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0116 | 0.4628 | 0.5769 |
Echinococcus multilocularis | sodium dependent neurotransmitter transporter | 0.0028 | 0.0528 | 0.0695 |
Toxoplasma gondii | thioredoxin reductase | 0.0051 | 0.1601 | 0.1989 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0018 | 0.0057 | 0.0306 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0418 | 0.0454 |
Toxoplasma gondii | Sodium:neurotransmitter symporter family protein | 0.0028 | 0.0528 | 0.0649 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0028 | 0.0528 | 0.0695 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.002 | 0.0151 | 0.0178 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.002 | 0.0151 | 0.0174 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0018 | 0.0057 | 0.0061 |
Treponema pallidum | sodium- and chloride- dependent transporter | 0.0164 | 0.6836 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0018 | 0.0057 | 0.0306 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0664 | 0.0895 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0039 | 0.103 | 0.1436 |
Entamoeba histolytica | hypothetical protein | 0.0038 | 0.0984 | 0.9472 |
Schistosoma mansoni | sodium-dependent amino acid transporter | 0.0028 | 0.0528 | 0.0695 |
Echinococcus multilocularis | sodium:chloride dependent neurotransmitter | 0.0028 | 0.0528 | 0.0695 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0116 | 0.4628 | 0.5769 |
Onchocerca volvulus | 0.0028 | 0.0528 | 0.052 | |
Schistosoma mansoni | sodium-dependent neurotransmitter transporter | 0.0028 | 0.0528 | 0.0695 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.002 | 0.0151 | 0.0118 |
Schistosoma mansoni | norepinephrine/norepinephrine transporter | 0.0028 | 0.0528 | 0.0695 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0097 | 0.3744 | 0.4206 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0018 | 0.0057 | 0.0306 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.