Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0025 | 0.021 | 0.2048 |
Echinococcus multilocularis | citrate lyase subunit beta protein | 0.0025 | 0.0214 | 0.0214 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0005 | 0.0007 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0027 | 0.0238 | 0.0095 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0196 | 0.2795 | 1 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.2404 | 0.2404 |
Plasmodium vivax | hypothetical protein, conserved | 0.0029 | 0.0276 | 0.2707 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0095 | 0.0141 |
Echinococcus multilocularis | cpg binding protein | 0.0033 | 0.0327 | 0.0327 |
Schistosoma mansoni | hypothetical protein | 0.0016 | 0.0077 | 0.0077 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase superfamily protein | 0.0047 | 0.0536 | 0.3112 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.1225 | 0.347 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0029 | 0.0276 | 0.0407 |
Mycobacterium tuberculosis | Conserved hypothetical protein | 0.0122 | 0.1668 | 0.5636 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0403 | 0.0659 |
Chlamydia trachomatis | holo [acyl-carrier protein] synthase | 0.0047 | 0.0536 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0068 | 0.0856 | 0.2208 |
Echinococcus multilocularis | dna polymerase eta | 0.0178 | 0.2521 | 0.2521 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0177 | 0.2497 | 0.8848 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0152 | 0.2121 | 0.6534 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0394 | 0.0394 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0095 | 0.0141 |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0038 | 0.0403 | 0.0659 |
Echinococcus multilocularis | sodium:glucose cotransporter 2 | 0.0039 | 0.0415 | 0.0415 |
Echinococcus multilocularis | high affinity choline transporter 1 | 0.0349 | 0.5106 | 0.5106 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.021 | 0.0311 |
Echinococcus granulosus | peregrin | 0.0029 | 0.0276 | 0.0276 |
Echinococcus multilocularis | muscleblind protein 1 | 0.046 | 0.6774 | 0.6774 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.021 | 0.0311 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0077 | 0.1001 | 0.2705 |
Echinococcus granulosus | sodium:myo inositol cotransporter | 0.0039 | 0.0415 | 0.0415 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0196 | 0.2795 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1225 | 0.5303 |
Echinococcus granulosus | cpg binding protein | 0.0033 | 0.0327 | 0.0327 |
Schistosoma mansoni | jumonji domain containing protein | 0.0134 | 0.1862 | 0.1862 |
Echinococcus granulosus | sodium coupled monocarboxylate transporter 1 | 0.0039 | 0.0415 | 0.0415 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0536 | 0.0536 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0246 | 0.0363 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0027 | 0.0238 | 0.0352 |
Brugia malayi | GH02984p | 0.0349 | 0.5106 | 0.7539 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0129 | 0.1781 | 0.537 |
Onchocerca volvulus | Alhambra homolog | 0.0029 | 0.0276 | 0.1184 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1225 | 0.5303 |
Entamoeba histolytica | deoxycytidyl transferase, putative | 0.0122 | 0.1668 | 1 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0029 | 0.0276 | 0.0276 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0095 | 0.1273 | 0.1273 |
Schistosoma mansoni | hypothetical protein | 0.017 | 0.2404 | 0.2404 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0025 | 0.021 | 0.021 |
Mycobacterium tuberculosis | Inositol-1-monophosphatase SuhB | 0.0033 | 0.0335 | 0.047 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0027 | 0.0238 | 0.0267 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0152 | 0.2121 | 0.6534 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0027 | 0.0238 | 0.0095 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0403 | 0.0659 |
Schistosoma mansoni | lamin | 0.0027 | 0.0246 | 0.0246 |
Echinococcus multilocularis | terminal deoxycytidyl transferase rev1 | 0.0122 | 0.1668 | 0.1668 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0152 | 0.2121 | 0.6534 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.0301 | 0.0301 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0154 | 0.216 | 0.216 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0091 | 0.1211 | 0.3423 |
Trypanosoma brucei | DNA polymerase eta, putative | 0.0178 | 0.2521 | 0.7903 |
Echinococcus multilocularis | inositol monophosphatase 1 | 0.0037 | 0.0394 | 0.0394 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0246 | 0.0246 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0025 | 0.021 | 0.021 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0017 | 0.0094 | 0.0094 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0246 | 0.0246 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0077 | 0.0114 |
Schistosoma mansoni | high-affinity choline transporter | 0.0349 | 0.5106 | 0.5106 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0029 | 0.0276 | 0.0276 |
Schistosoma mansoni | DNA polymerase IV / kappa | 0.0038 | 0.0403 | 0.0403 |
Mycobacterium ulcerans | extragenic suppressor protein SuhB | 0.0037 | 0.0394 | 0.0944 |
Wolbachia endosymbiont of Brugia malayi | 4'-phosphopantetheinyl transferase | 0.0047 | 0.0536 | 1 |
Onchocerca volvulus | 0.0165 | 0.233 | 1 | |
Plasmodium vivax | holo-[acyl-carrier-protein] synthase, putative | 0.0047 | 0.0536 | 0.532 |
Mycobacterium tuberculosis | Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) | 0.0129 | 0.1781 | 0.6072 |
Toxoplasma gondii | inositol(myo)-1(or 4)-monophosphatase 2, putative | 0.0037 | 0.0394 | 0.1755 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0025 | 0.021 | 0.021 |
Schistosoma mansoni | aminoadipate-semialdehyde dehydrogenase | 0.0165 | 0.233 | 0.233 |
Trypanosoma brucei | unspecified product | 0.0084 | 0.1099 | 0.3038 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0025 | 0.0214 | 0.0012 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0152 | 0.2121 | 0.6534 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.6774 | 1 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.002 | 0.0131 | 0.0193 |
Brugia malayi | CXXC zinc finger family protein | 0.0031 | 0.0301 | 0.0444 |
Loa Loa (eye worm) | ImpB/MucB/SamB family protein | 0.0122 | 0.1668 | 0.2463 |
Loa Loa (eye worm) | hypothetical protein | 0.046 | 0.6774 | 1 |
Echinococcus granulosus | terminal deoxycytidyl transferase rev1 | 0.0122 | 0.1668 | 0.1668 |
Loa Loa (eye worm) | hypothetical protein | 0.0178 | 0.2521 | 0.3722 |
Loa Loa (eye worm) | hypothetical protein | 0.0349 | 0.5106 | 0.7539 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0219 | 0.3135 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0027 | 0.0238 | 0.0095 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0027 | 0.0238 | 0.0128 |
Echinococcus granulosus | high affinity choline transporter 1 | 0.0349 | 0.5106 | 0.5106 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0219 | 0.3135 | 1 |
Trypanosoma brucei | trypanothione reductase | 0.0077 | 0.1001 | 0.2705 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0152 | 0.2121 | 1 |
Onchocerca volvulus | 0.0027 | 0.0246 | 0.1056 | |
Brugia malayi | Protein kinase domain containing protein | 0.0017 | 0.0095 | 0.0141 |
Schistosoma mansoni | terminal deoxycytidyl transferase | 0.0122 | 0.1668 | 0.1668 |
Leishmania major | hypothetical protein, conserved | 0.0219 | 0.3135 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0047 | 0.0536 | 0.1113 |
Onchocerca volvulus | 0.0027 | 0.0246 | 0.1056 | |
Leishmania major | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0025 | 0.0214 | 0.0012 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0196 | 0.2795 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0027 | 0.0238 | 0.0095 |
Brugia malayi | PHD-finger family protein | 0.0029 | 0.0276 | 0.0407 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0246 | 0.0246 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0094 | 0.1256 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1225 | 0.5303 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0095 | 0.1273 | 0.1273 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0027 | 0.0238 | 0.0095 |
Trypanosoma brucei | polo-like protein kinase | 0.0092 | 0.1225 | 0.347 |
Loa Loa (eye worm) | DOMON domain-containing protein | 0.0016 | 0.0077 | 0.0114 |
Echinococcus granulosus | lamin | 0.0027 | 0.0246 | 0.0246 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1225 | 0.5303 |
Mycobacterium ulcerans | 4'-phosphopantetheinyl transferase | 0.0047 | 0.0536 | 0.1688 |
Trichomonas vaginalis | DNA polymerase IV / kappa, putative | 0.0152 | 0.2121 | 1 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0027 | 0.0238 | 0.0128 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0536 | 0.0536 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0077 | 0.1001 | 0.3052 |
Brugia malayi | Muscleblind-like protein | 0.046 | 0.6774 | 1 |
Schistosoma mansoni | kinase | 0.0047 | 0.0541 | 0.0541 |
Plasmodium falciparum | DNA repair protein REV1, putative | 0.0038 | 0.0403 | 0.3985 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0027 | 0.0238 | 0.2329 |
Echinococcus granulosus | geminin | 0.017 | 0.2404 | 0.2404 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0027 | 0.0238 | 0.0095 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0027 | 0.0238 | 0.0095 |
Mycobacterium ulcerans | hypothetical protein | 0.0038 | 0.0403 | 0.0992 |
Plasmodium falciparum | phd finger protein, putative | 0.0029 | 0.0276 | 0.2707 |
Schistosoma mansoni | hypothetical protein | 0.0062 | 0.077 | 0.077 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0027 | 0.0238 | 0.0128 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0154 | 0.216 | 0.216 |
Trichomonas vaginalis | inositol monophosphatase, putative | 0.0037 | 0.0394 | 0.0944 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0095 | 0.1273 | 0.1273 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0025 | 0.021 | 0.0311 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0276 | 0.0626 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.002 | 0.0131 | 0.0193 |
Loa Loa (eye worm) | hypothetical protein | 0.0066 | 0.0826 | 0.1219 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0027 | 0.0238 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.0856 | 0.1264 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.0536 | 0.0791 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0092 | 0.1225 | 0.5258 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0239 | 0.0352 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0068 | 0.0856 | 0.2208 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0536 | 0.0536 |
Giardia lamblia | PHD finger protein 15 | 0.0029 | 0.0276 | 0.0244 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0078 | 0.1017 | 0.1017 |
Loa Loa (eye worm) | TK/ALK protein kinase | 0.0017 | 0.0095 | 0.0141 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0177 | 0.2497 | 0.8848 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.021 | 0.0311 |
Schistosoma mansoni | phd/f-box containing protein | 0.0025 | 0.021 | 0.021 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0095 | 0.0141 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.021 | 0.0311 |
Mycobacterium leprae | conserved hypothetical protein | 0.0047 | 0.0536 | 0.0816 |
Plasmodium falciparum | glutathione reductase | 0.0077 | 0.1001 | 1 |
Schistosoma mansoni | inositol transporter | 0.0039 | 0.0415 | 0.0415 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0027 | 0.0238 | 0.0267 |
Echinococcus granulosus | dnaJ subfamily C 6 | 0.0062 | 0.077 | 0.077 |
Brugia malayi | jmjC domain containing protein | 0.0025 | 0.021 | 0.0311 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0177 | 0.2497 | 0.8791 |
Schistosoma mansoni | lamin | 0.0027 | 0.0246 | 0.0246 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0027 | 0.0238 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.0165 | 0.233 | 0.344 |
Wolbachia endosymbiont of Brugia malayi | fructose-1,6-bisphosphatase | 0.0037 | 0.0394 | 0.5231 |
Plasmodium vivax | glutathione reductase, putative | 0.0077 | 0.1001 | 1 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0674 | 1 | 1 |
Echinococcus granulosus | solute carrier family 5 | 0.0039 | 0.0415 | 0.0415 |
Echinococcus granulosus | sodium:glucose cotransporter | 0.0039 | 0.0415 | 0.0415 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0523 | 0.1619 |
Plasmodium vivax | JmjC domain containing protein | 0.0025 | 0.021 | 0.2048 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0033 | 0.0033 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0092 | 0.1225 | 0.347 |
Brugia malayi | SEA domain containing protein | 0.0016 | 0.0077 | 0.0114 |
Onchocerca volvulus | 0.0016 | 0.0077 | 0.0331 | |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0246 | 0.0363 |
Schistosoma mansoni | rab geranylgeranyl transferase alpha subunit | 0.0122 | 0.1668 | 0.1668 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0152 | 0.2121 | 0.6534 |
Echinococcus multilocularis | L aminoadipate semialdehyde | 0.0165 | 0.233 | 0.233 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0027 | 0.0238 | 0.2329 |
Giardia lamblia | Kinase, PLK | 0.0092 | 0.1225 | 0.6399 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0027 | 0.0238 | 0.2329 |
Giardia lamblia | DINP protein human, muc B family | 0.0129 | 0.1781 | 1 |
Onchocerca volvulus | 0.0016 | 0.0077 | 0.0331 | |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0122 | 0.1668 | 0.2463 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0025 | 0.021 | 0.021 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0046 | 0.0523 | 0.1619 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0038 | 0.0403 | 0.0659 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.0077 | 0.0114 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0078 | 0.1017 | 0.1017 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0027 | 0.0237 | 0.0237 |
Leishmania major | trypanothione reductase | 0.0077 | 0.1001 | 0.2705 |
Echinococcus multilocularis | peregrin | 0.0029 | 0.0276 | 0.0276 |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0152 | 0.2121 | 0.6534 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1225 | 0.5303 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0027 | 0.0238 | 0.0095 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0066 | 0.0824 | 0.0824 |
Entamoeba histolytica | hypothetical protein | 0.0047 | 0.0536 | 0.1214 |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0178 | 0.2521 | 0.7903 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0027 | 0.0238 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.021 | 0.0311 |
Onchocerca volvulus | 0.0016 | 0.0077 | 0.0331 | |
Trypanosoma brucei | DNA damage repair protein, putative | 0.0038 | 0.0403 | 0.0659 |
Onchocerca volvulus | 0.0016 | 0.0077 | 0.0331 | |
Onchocerca volvulus | 0.0039 | 0.0415 | 0.1782 | |
Trypanosoma brucei | hypothetical protein, conserved | 0.0038 | 0.0403 | 0.0659 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0394 | 0.0628 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0027 | 0.0238 | 0.0238 |
Giardia lamblia | DNA damage repair protein | 0.0038 | 0.0403 | 0.1068 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0536 | 0.0536 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0025 | 0.021 | 0.021 |
Echinococcus granulosus | citrate lyase subunit beta protein | 0.0025 | 0.0214 | 0.0214 |
Echinococcus granulosus | MAM | 0.0017 | 0.0095 | 0.0095 |
Trypanosoma brucei | inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0394 | 0.0628 |
Echinococcus multilocularis | muscleblind protein | 0.046 | 0.6774 | 0.6774 |
Echinococcus granulosus | muscleblind protein | 0.046 | 0.6774 | 0.6774 |
Toxoplasma gondii | ImpB/MucB/SamB family protein | 0.0038 | 0.0403 | 0.1843 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0077 | 0.1001 | 1 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.0055 | 0.0081 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1225 | 0.5303 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0246 | 0.0246 |
Onchocerca volvulus | 0.0017 | 0.0095 | 0.041 | |
Trypanosoma cruzi | DNA polymerase eta, putative | 0.0094 | 0.1256 | 0.3576 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0027 | 0.0238 | 0.0095 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0152 | 0.2121 | 0.6534 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0025 | 0.021 | 0.021 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.0276 | 0.0407 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0394 | 0.0944 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0027 | 0.0238 | 0.0095 |
Onchocerca volvulus | 0.0016 | 0.0077 | 0.0331 | |
Trypanosoma brucei | DNA polymerase IV, putative | 0.0144 | 0.2009 | 0.615 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0027 | 0.0238 | 0.0128 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0327 | 0.0327 |
Mycobacterium ulcerans | phosphopantetheinyl transferase, PptII | 0.0047 | 0.0536 | 0.1688 |
Toxoplasma gondii | BRCA1 C Terminus (BRCT) domain-containing protein | 0.0045 | 0.0515 | 0.2917 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0019 | 0.0121 | 0.0178 |
Echinococcus multilocularis | MAM | 0.0017 | 0.0095 | 0.0095 |
Leishmania major | DNA polymerase eta, putative | 0.0178 | 0.2521 | 0.7903 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.0536 | 0.0536 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0095 | 0.0095 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0036 | 0.0379 | 0.0379 |
Mycobacterium tuberculosis | holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie | 0.0047 | 0.0536 | 0.1248 |
Echinococcus granulosus | sodium:glucose cotransporter 2 | 0.0039 | 0.0415 | 0.0415 |
Trypanosoma brucei | unspecified product | 0.0144 | 0.2009 | 0.615 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0196 | 0.2795 | 1 |
Echinococcus multilocularis | sodium:myo inositol cotransporter | 0.0039 | 0.0415 | 0.0415 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0152 | 0.2121 | 0.6534 |
Leishmania major | DNA polymerase kappa, putative | 0.0129 | 0.1781 | 0.537 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.0055 | 0.0081 |
Brugia malayi | jmjC domain containing protein | 0.0154 | 0.216 | 0.3188 |
Loa Loa (eye worm) | hypothetical protein | 0.0039 | 0.0415 | 0.0613 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.0536 | 0.0791 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0036 | 0.0379 | 0.0379 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0027 | 0.0238 | 0.2329 |
Brugia malayi | hypothetical protein | 0.0036 | 0.0379 | 0.056 |
Leishmania major | phosphopantetheinyl transferase-like protein | 0.0047 | 0.0536 | 0.1113 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0059 | 0.0718 | 0.4857 |
Leishmania major | DNA polymerase eta, putative | 0.0094 | 0.1256 | 0.3576 |
Brugia malayi | Thioredoxin reductase | 0.0077 | 0.1001 | 0.1478 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0152 | 0.2121 | 0.6534 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.0536 | 0.0536 |
Schistosoma mansoni | protein phosphatase 2C | 0.0025 | 0.021 | 0.021 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0033 | 0.0033 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0246 | 0.0363 |
Echinococcus multilocularis | dna polymerase kappa | 0.0152 | 0.2121 | 0.2121 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0246 | 0.0246 |
Echinococcus multilocularis | geminin | 0.017 | 0.2404 | 0.2404 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0027 | 0.0238 | 0.0128 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0027 | 0.0238 | 0.0238 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0177 | 0.2497 | 0.8848 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0152 | 0.2121 | 0.6534 |
Treponema pallidum | 4'-phosphopantetheinyl transferase | 0.0047 | 0.0536 | 1 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0091 | 0.1211 | 0.3423 |
Brugia malayi | glutathione reductase | 0.0077 | 0.1001 | 0.1478 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0061 | 0.0747 | 0.1103 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0029 | 0.0276 | 0.0626 |
Echinococcus granulosus | inositol monophosphatase 1 | 0.0037 | 0.0394 | 0.0394 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0177 | 0.2497 | 0.8848 |
Brugia malayi | DnaJ domain containing protein | 0.0062 | 0.077 | 0.1136 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0077 | 0.1001 | 0.1478 |
Onchocerca volvulus | 0.0031 | 0.0301 | 0.129 | |
Brugia malayi | aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase | 0.0165 | 0.233 | 0.344 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0674 | 1 | 1 |
Loa Loa (eye worm) | glutathione reductase | 0.0077 | 0.1001 | 0.1478 |
Toxoplasma gondii | transporter, solute:sodium symporter (SSS) family protein | 0.0039 | 0.0415 | 0.1958 |
Leishmania major | DNA polymerase kappa, putative,DNA polymerase IV, putative | 0.0129 | 0.1781 | 0.537 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0041 | 0.0449 | 0.0449 |
Mycobacterium ulcerans | DNA polymerase IV | 0.0152 | 0.2121 | 1 |
Trichomonas vaginalis | DNA polymerase eta, putative | 0.0152 | 0.2121 | 1 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0094 | 0.1246 | 0.1246 |
Loa Loa (eye worm) | inositol-1 | 0.0037 | 0.0394 | 0.0582 |
Schistosoma mansoni | jumonji domain containing protein | 0.0025 | 0.021 | 0.021 |
Schistosoma mansoni | hypothetical protein | 0.0029 | 0.0276 | 0.0276 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0092 | 0.1225 | 0.5303 |
Echinococcus granulosus | jumonji domain containing protein | 0.0041 | 0.0449 | 0.0449 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0092 | 0.1225 | 0.347 |
Loa Loa (eye worm) | DnaJ domain-containing protein | 0.0062 | 0.077 | 0.1136 |
Brugia malayi | Inositol-1 | 0.0037 | 0.0394 | 0.0582 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0095 | 0.0095 |
Trichomonas vaginalis | myo inositol monophosphatase, putative | 0.0037 | 0.0394 | 0.0944 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0091 | 0.1211 | 0.3423 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.0536 | 0.0536 |
Plasmodium falciparum | holo-[acyl-carrier-protein] synthase, putative | 0.0047 | 0.0536 | 0.532 |
Schistosoma mansoni | sodium/solute symporter | 0.0039 | 0.0415 | 0.0415 |
Trypanosoma brucei | chrX additional, unordered contigs | 0.0038 | 0.0403 | 0.0659 |
Brugia malayi | Sodium:solute symporter family protein | 0.0039 | 0.0415 | 0.0613 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0246 | 0.0363 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0025 | 0.0037 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0152 | 0.2121 | 0.6534 |
Plasmodium falciparum | glutathione reductase | 0.0027 | 0.0238 | 0.2329 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0092 | 0.1225 | 0.6562 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0027 | 0.0238 | 0.0095 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0038 | 0.0403 | 0.0659 |
Brugia malayi | Bromodomain containing protein | 0.0029 | 0.0276 | 0.0407 |
Trypanosoma cruzi | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0394 | 0.0628 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0025 | 0.021 | 0.021 |
Plasmodium falciparum | thioredoxin reductase | 0.0027 | 0.0238 | 0.2329 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0177 | 0.2497 | 0.8848 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0027 | 0.0237 | 0.0237 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0095 | 0.1273 | 0.188 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0092 | 0.1225 | 0.1809 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0152 | 0.2121 | 0.6534 |
Trypanosoma brucei | unspecified product | 0.0084 | 0.1099 | 0.3038 |
Brugia malayi | polk-prov protein | 0.0068 | 0.0856 | 0.1264 |
Trypanosoma cruzi | DNA damage repair protein, putative | 0.0038 | 0.0403 | 0.0659 |
Brugia malayi | jmjC domain containing protein | 0.0095 | 0.1273 | 0.188 |
Plasmodium falciparum | thioredoxin reductase | 0.0077 | 0.1001 | 1 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0246 | 0.0246 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0031 | 0.0301 | 0.0444 |
Leishmania major | DNA damage repair protein, putative | 0.0038 | 0.0403 | 0.0659 |
Onchocerca volvulus | 0.0017 | 0.0095 | 0.041 | |
Schistosoma mansoni | inositol transporter | 0.0039 | 0.0415 | 0.0415 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0219 | 0.3135 | 1 |
Schistosoma mansoni | DNA polymerase eta | 0.0178 | 0.2521 | 0.2521 |
Plasmodium vivax | DNA repair protein REV1, putative | 0.0038 | 0.0403 | 0.3985 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0092 | 0.1225 | 0.1225 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0036 | 0.0379 | 0.0379 |
Trypanosoma cruzi | DNA polymerase kappa, putative | 0.0152 | 0.2121 | 0.6534 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0025 | 0.021 | 0.0311 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0152 | 0.2121 | 0.6534 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0025 | 0.0037 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0027 | 0.0238 | 0.0238 |
Brugia malayi | ImpB/MucB/SamB family protein | 0.0178 | 0.2521 | 0.3722 |
Trichomonas vaginalis | protein kinase inhibitor, putative | 0.0062 | 0.077 | 0.2913 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0027 | 0.0238 | 0.0095 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0033 | 0.0048 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0025 | 0.0214 | 0.0012 |
Brugia malayi | Muscle positioning protein 4 | 0.0016 | 0.0077 | 0.0114 |
Entamoeba histolytica | myo-inositol monophosphatase, putative | 0.0037 | 0.0394 | 0.0113 |
Mycobacterium tuberculosis | Probable reductase | 0.0177 | 0.2497 | 0.8848 |
Schistosoma mansoni | cpg binding protein | 0.0033 | 0.0327 | 0.0327 |
Echinococcus multilocularis | dnaJ subfamily C 6 | 0.0062 | 0.077 | 0.077 |
Schistosoma mansoni | inositol monophosphatase | 0.0037 | 0.0394 | 0.0394 |
Echinococcus granulosus | dna polymerase kappa | 0.0152 | 0.2121 | 0.2121 |
Brugia malayi | PHD-finger family protein | 0.0011 | 0.0005 | 0.0007 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0029 | 0.0276 | 0.0276 |
Toxoplasma gondii | 4'-phosphopantetheinyl transferase domain-containing protein | 0.0047 | 0.0536 | 0.3112 |
Trypanosoma brucei | DNA polymerase kappa, putative | 0.0152 | 0.2121 | 0.6534 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0092 | 0.1225 | 0.1225 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0092 | 0.1225 | 0.1225 |
Echinococcus multilocularis | solute carrier family 5 | 0.0039 | 0.0415 | 0.0415 |
Schistosoma mansoni | hypothetical protein | 0.0036 | 0.0379 | 0.0379 |
Leishmania major | DNA polymerase kappa, putative | 0.0038 | 0.0403 | 0.0659 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0027 | 0.0238 | 0.0095 |
Echinococcus multilocularis | phd:f box containing protein | 0.0025 | 0.021 | 0.021 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0025 | 0.021 | 0.021 |
Echinococcus multilocularis | sodium coupled monocarboxylate transporter 1 | 0.0039 | 0.0415 | 0.0415 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0095 | 0.0141 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0092 | 0.1225 | 0.1809 |
Echinococcus granulosus | L aminoadipate semialdehyde | 0.0165 | 0.233 | 0.233 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0246 | 0.0363 |
Echinococcus granulosus | dna polymerase eta | 0.0178 | 0.2521 | 0.2521 |
Toxoplasma gondii | thioredoxin reductase | 0.0077 | 0.1001 | 0.7564 |
Echinococcus granulosus | phd:f box containing protein | 0.0025 | 0.021 | 0.021 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0027 | 0.0238 | 0.0095 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0027 | 0.0238 | 0.0095 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0025 | 0.021 | 0.0311 |
Leishmania major | myo-inositol-1(or 4)-monophosphatase 1, putative | 0.0037 | 0.0394 | 0.0628 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.