Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0024 | 0 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0024 | 0 | 0.5 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0037 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0143 | 1 | 1 |
Onchocerca volvulus | 0.0024 | 0 | 0.5 | |
Onchocerca volvulus | 0.0024 | 0 | 0.5 | |
Brugia malayi | hypothetical protein | 0.0025 | 0.0037 | 0.0037 |
Onchocerca volvulus | 0.0024 | 0 | 0.5 | |
Echinococcus multilocularis | acetylcholinesterase | 0.0143 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0143 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0143 | 1 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0037 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0025 | 0.0037 | 0.5 |
Leishmania major | hypothetical protein, conserved | 0.0025 | 0.0037 | 0.5 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0025 | 0.0037 | 0.5 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0025 | 0.0037 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0143 | 1 | 1 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0143 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.0143 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0143 | 1 | 1 |
Mycobacterium tuberculosis | Carboxylesterase LipT | 0.0024 | 0 | 0.5 |
Onchocerca volvulus | 0.0024 | 0 | 0.5 | |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0024 | 0 | 0.5 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0143 | 1 | 1 |
Onchocerca volvulus | 0.0024 | 0 | 0.5 | |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0025 | 0.0037 | 0.5 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0143 | 1 | 1 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0025 | 0.0037 | 0.5 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0024 | 0 | 0.5 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0024 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0143 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0025 | 0.0037 | 0.0037 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.