Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Carboxylesterase family protein | 0.0058 | 0.018 | 0.0416 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.018 | 0.0416 |
Echinococcus multilocularis | family S9 non peptidase ue (S09 family) | 0.0058 | 0.018 | 0.0416 |
Mycobacterium ulcerans | carboxylesterase, LipT | 0.0326 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1509 | 0.3492 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.018 | 0.0416 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0058 | 0.018 | 0.018 |
Echinococcus multilocularis | BC026374 protein (S09 family) | 0.0058 | 0.018 | 0.0416 |
Onchocerca volvulus | 0.0058 | 0.018 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.018 | 0.0416 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0094 | 0.1509 | 0.3492 |
Entamoeba histolytica | aldehyde dehydrogenase 1, putative | 0.0053 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4322 | 1 |
Onchocerca volvulus | 0.0058 | 0.018 | 1 | |
Brugia malayi | Carboxylesterase family protein | 0.0058 | 0.018 | 0.0416 |
Trypanosoma cruzi | aldehyde dehydrogenase family, putative | 0.0053 | 0 | 0.5 |
Echinococcus granulosus | BC026374 protein S09 family | 0.0058 | 0.018 | 0.0416 |
Schistosoma mansoni | neuroligin 3 (S09 family) | 0.0058 | 0.018 | 0.0416 |
Mycobacterium leprae | PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDENT | 0.0053 | 0 | 0.5 |
Schistosoma mansoni | gliotactin | 0.0058 | 0.018 | 0.0416 |
Loa Loa (eye worm) | carboxylesterase | 0.0058 | 0.018 | 0.0416 |
Trypanosoma cruzi | aldehyde dehydrogenase family, putative | 0.0053 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0171 | 0.4322 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0171 | 0.4322 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0058 | 0.018 | 0.0416 |
Echinococcus multilocularis | neuroligin | 0.0058 | 0.018 | 0.0416 |
Loa Loa (eye worm) | Sodium:neurotransmitter symporter family protein | 0.0094 | 0.1509 | 0.3492 |
Schistosoma mansoni | acetylcholinesterase | 0.0058 | 0.018 | 0.0416 |
Echinococcus granulosus | acetylcholinesterase | 0.0171 | 0.4322 | 1 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0094 | 0.1509 | 0.3492 |
Echinococcus multilocularis | para nitrobenzyl esterase | 0.0058 | 0.018 | 0.0416 |
Echinococcus granulosus | neuroligin | 0.0058 | 0.018 | 0.0416 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0058 | 0.018 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0171 | 0.4322 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.0171 | 0.4322 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0171 | 0.4322 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.018 | 0.0416 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0094 | 0.1509 | 0.3492 |
Loa Loa (eye worm) | carboxylesterase | 0.0171 | 0.4322 | 1 |
Schistosoma mansoni | BC026374 protein (S09 family) | 0.0058 | 0.018 | 0.0416 |
Onchocerca volvulus | 0.0058 | 0.018 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.018 | 0.0416 |
Echinococcus granulosus | sodium and chloride dependent glycine | 0.0094 | 0.1509 | 0.3492 |
Echinococcus granulosus | family S9 non peptidase ue S09 family | 0.0058 | 0.018 | 0.0416 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0058 | 0.018 | 0.0416 |
Echinococcus granulosus | para nitrobenzyl esterase | 0.0058 | 0.018 | 0.0416 |
Brugia malayi | Carboxylesterase family protein | 0.0058 | 0.018 | 0.0416 |
Onchocerca volvulus | 0.0058 | 0.018 | 1 | |
Brugia malayi | hypothetical protein | 0.0058 | 0.018 | 0.0416 |
Trypanosoma brucei | aldehyde dehydrogenase family, putative | 0.0053 | 0 | 0.5 |
Echinococcus multilocularis | sodium and chloride dependent glycine | 0.0094 | 0.1509 | 0.3492 |
Schistosoma mansoni | sodium/chloride dependent transporter | 0.0094 | 0.1509 | 0.3492 |
Onchocerca volvulus | 0.0058 | 0.018 | 1 | |
Brugia malayi | Sodium:neurotransmitter symporter family protein | 0.0094 | 0.1509 | 0.3492 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0058 | 0.018 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.018 | 0.0416 |
Loa Loa (eye worm) | hypothetical protein | 0.0094 | 0.1509 | 0.3492 |
Echinococcus multilocularis | acetylcholinesterase | 0.0171 | 0.4322 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0058 | 0.018 | 0.0416 |
Loa Loa (eye worm) | hypothetical protein | 0.0171 | 0.4322 | 1 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0171 | 0.4322 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0171 | 0.4322 | 1 |
Mycobacterium tuberculosis | POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) | 0.0058 | 0.018 | 0.018 |
Brugia malayi | Carboxylesterase family protein | 0.0058 | 0.018 | 0.0416 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0171 | 0.4322 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0058 | 0.018 | 0.0416 |
Loa Loa (eye worm) | carboxylesterase | 0.0058 | 0.018 | 0.0416 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.