Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0032 | 0.027 | 0.2803 |
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.001 | 0.0022 | 0.0086 |
Loa Loa (eye worm) | RecQ helicase | 0.0026 | 0.0201 | 0.0539 |
Leishmania major | GTP-binding protein, putative | 0.0023 | 0.0167 | 0.1733 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0045 | 0.0417 | 0.0417 |
Trypanosoma cruzi | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0062 | 0.0646 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0209 | 0.232 | 0.8958 |
Echinococcus multilocularis | smad | 0.0009 | 0.0004 | 0.0004 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0019 | 0.0121 | 0.4488 |
Plasmodium falciparum | glutathione reductase | 0.0092 | 0.0962 | 1 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0084 | 0.0876 | 0.0876 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.001 | 0.0022 | 0.0086 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.004 | 0.0361 | 0.0371 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.008 | 0.0082 |
Schistosoma mansoni | DNA helicase recq1 | 0.0011 | 0.0026 | 0.0027 |
Echinococcus multilocularis | GTP binding nuclear protein Ran | 0.0023 | 0.0167 | 0.0167 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0032 | 0.027 | 0.0307 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0361 | 0.0968 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0032 | 0.027 | 0.2803 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0084 | 0.0876 | 0.216 |
Mycobacterium ulcerans | cytochrome P450 143A4 Cyp143A4 | 0.001 | 0.0022 | 0.0825 |
Loa Loa (eye worm) | Smad1 | 0.0009 | 0.0004 | 0.001 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0876 | 0.2344 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0084 | 0.0876 | 0.216 |
Brugia malayi | hypothetical protein | 0.004 | 0.0361 | 0.0892 |
Echinococcus multilocularis | importin subunit beta 1 | 0.0031 | 0.0262 | 0.0262 |
Trypanosoma brucei | trypanothione reductase | 0.0092 | 0.0962 | 1 |
Mycobacterium ulcerans | cytochrome P450 187A4 Cyp187A4 | 0.001 | 0.0022 | 0.0825 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0032 | 0.027 | 0.0666 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.027 | 0.2803 |
Schistosoma mansoni | zinc finger protein | 0.004 | 0.0361 | 0.0371 |
Brugia malayi | Muscleblind-like protein | 0.0146 | 0.1587 | 0.3916 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.027 | 0.2803 |
Mycobacterium ulcerans | cytochrome P450 105Q4 Cyp105Q4 | 0.001 | 0.0022 | 0.0825 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.001 | 0.0022 | 0.0086 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0017 | 0.0102 | 0.1062 |
Mycobacterium ulcerans | cytochrome P450 108B4 Cyp108B4 | 0.001 | 0.0022 | 0.0825 |
Schistosoma mansoni | nuclear hormone receptor | 0.004 | 0.0361 | 0.0371 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0209 | 0.232 | 0.8958 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.008 | 0.008 |
Mycobacterium ulcerans | cytochrome P450 189A7 Cyp189A7 | 0.001 | 0.0022 | 0.0825 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0084 | 0.0876 | 0.0997 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0092 | 0.0962 | 0.2576 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0011 | 0.0026 | 0.0064 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0032 | 0.027 | 0.2803 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0084 | 0.0876 | 0.0898 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0209 | 0.232 | 0.8958 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0351 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.032 | 0.3594 | 0.9621 |
Mycobacterium ulcerans | cytochrome P450 140A5 Cyp140A5 | 0.001 | 0.0022 | 0.0825 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.004 | 0.0361 | 0.0892 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.001 | 0.0022 | 0.0086 |
Plasmodium vivax | GTP-binding nuclear protein RAN/TC4, putative | 0.0023 | 0.0167 | 0.1733 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0032 | 0.027 | 1 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0032 | 0.027 | 0.027 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0876 | 0.2344 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0417 | 0.1115 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0039 | 0.0351 | 0.0351 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0417 | 0.1115 |
Brugia malayi | nuclear hormone receptor | 0.0084 | 0.0876 | 0.216 |
Mycobacterium ulcerans | cytochrome P450 187A5 Cyp187A5 | 0.001 | 0.0022 | 0.0825 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0876 | 0.2344 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0084 | 0.0876 | 0.0997 |
Onchocerca volvulus | Bile acid receptor homolog | 0.0084 | 0.0876 | 1 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.0121 | 0.1258 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.1587 | 0.4249 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0014 | 0.0062 | 0.2306 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0121 | 0.0299 |
Plasmodium falciparum | thioredoxin reductase | 0.0032 | 0.027 | 0.2803 |
Plasmodium vivax | importin-beta 2, putative | 0.0031 | 0.0262 | 0.2718 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0351 | 1 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0084 | 0.0876 | 0.0876 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.008 | 0.008 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0019 | 0.0121 | 0.1258 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0092 | 0.0969 | 0.0969 |
Mycobacterium ulcerans | cytochrome P450 136A2 Cyp136A2 | 0.001 | 0.0022 | 0.0825 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0023 | 0.0167 | 0.1733 |
Brugia malayi | nuclear hormone receptor | 0.004 | 0.0361 | 0.0892 |
Schistosoma mansoni | hypothetical protein | 0.0033 | 0.0287 | 0.0294 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.004 | 0.0361 | 0.0892 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0361 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0361 | 0.0968 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.0084 | 0.0876 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0009 | 0.0001 | 0.0004 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0032 | 0.027 | 0.2803 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.001 | 0.0022 | 0.0086 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.004 | 0.0361 | 0.0361 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0032 | 0.027 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0084 | 0.0876 | 0.0876 |
Leishmania major | lanosterol 14-alpha-demethylase, putative | 0.001 | 0.0022 | 0.0231 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0361 | 0.0968 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0004 | 0.0009 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0084 | 0.0876 | 0.2344 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.027 | 0.2803 |
Schistosoma mansoni | DNA helicase recq5 | 0.0011 | 0.0026 | 0.0027 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0032 | 0.027 | 0.2803 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0004 | 0.0009 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0084 | 0.0876 | 0.0997 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0084 | 0.0876 | 0.216 |
Mycobacterium ulcerans | cytochrome P450 188A3 Cyp188A3 | 0.001 | 0.0022 | 0.0825 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0084 | 0.0876 | 0.216 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0361 | 0.0968 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0045 | 0.0417 | 0.0427 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0084 | 0.0876 | 0.216 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0361 | 0.0968 |
Schistosoma mansoni | thyroid hormone receptor | 0.0853 | 0.975 | 1 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0092 | 0.0962 | 1 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0032 | 0.027 | 0.1042 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0045 | 0.0417 | 0.0475 |
Loa Loa (eye worm) | DR-78 | 0.004 | 0.0361 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.013 | 0.1407 | 0.3767 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0032 | 0.027 | 0.2803 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0032 | 0.027 | 0.2803 |
Onchocerca volvulus | 0.004 | 0.0361 | 0.4129 | |
Mycobacterium leprae | Conserved hypothetical protein | 0.001 | 0.0022 | 0.0086 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.0084 | 0.0876 | 1 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0049 | 0.0465 | 0.1147 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.004 | 0.0361 | 0.0412 |
Echinococcus granulosus | mothers against decapentaplegic 5 | 0.0009 | 0.0004 | 0.0004 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0084 | 0.0876 | 0.0997 |
Loa Loa (eye worm) | hypothetical protein | 0.0146 | 0.1587 | 0.4249 |
Schistosoma mansoni | ran | 0.0023 | 0.0167 | 0.0171 |
Mycobacterium leprae | putative cytochrome p450 | 0.001 | 0.0022 | 0.0086 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0129 | 0.1389 | 0.3719 |
Echinococcus granulosus | GTP binding nuclear protein Ran | 0.0023 | 0.0167 | 0.019 |
Schistosoma mansoni | ran | 0.0023 | 0.0167 | 0.0171 |
Trichomonas vaginalis | DNA helicase recq, putative | 0.0026 | 0.0201 | 0.7467 |
Brugia malayi | RNA, U transporter 1 | 0.0088 | 0.0924 | 0.2279 |
Mycobacterium ulcerans | cytochrome P450 124A1, Cyp124A1 | 0.001 | 0.0022 | 0.0825 |
Leishmania major | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0062 | 0.0646 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.004 | 0.0361 | 0.4129 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0092 | 0.0969 | 0.1104 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0417 | 0.1115 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0084 | 0.0876 | 0.216 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.004 | 0.0361 | 0.0361 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.004 | 0.0361 | 0.0361 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0032 | 0.027 | 0.2803 |
Echinococcus granulosus | bloom syndrome protein | 0.0026 | 0.0201 | 0.0229 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0032 | 0.027 | 0.2803 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.004 | 0.0361 | 0.0892 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.004 | 0.0361 | 0.0968 |
Mycobacterium ulcerans | cytochrome p450 150 cyp150 | 0.001 | 0.0022 | 0.0825 |
Plasmodium falciparum | thioredoxin reductase | 0.0092 | 0.0962 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0233 | 0.259 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0084 | 0.0876 | 0.0898 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0361 | 0.0968 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0084 | 0.0876 | 0.2344 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0084 | 0.0876 | 0.216 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0361 | 0.0968 |
Schistosoma mansoni | nuclear receptor | 0.004 | 0.0361 | 0.0371 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.027 | 0.2803 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.001 | 0.0022 | 0.0086 |
Brugia malayi | Nuclear hormone receptor E75 | 0.004 | 0.0361 | 0.0892 |
Echinococcus multilocularis | mothers against decapentaplegic 5 | 0.0009 | 0.0004 | 0.0004 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0209 | 0.232 | 0.8958 |
Schistosoma mansoni | cytochrome P450 | 0.001 | 0.0022 | 0.0023 |
Mycobacterium ulcerans | cytochrome P450 142A3 Cyp142A3 | 0.001 | 0.0022 | 0.0825 |
Brugia malayi | hypothetical protein | 0.004 | 0.0361 | 0.0892 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.004 | 0.0361 | 0.0361 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0032 | 0.027 | 1 |
Leishmania major | cytochrome p450-like protein | 0.0019 | 0.0121 | 0.1258 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0084 | 0.0876 | 0.2344 |
Leishmania major | cytochrome p450-like protein | 0.001 | 0.0022 | 0.0231 |
Trichomonas vaginalis | importin beta-1, putative | 0.0025 | 0.0194 | 0.7179 |
Brugia malayi | Importin beta-1 subunit | 0.0031 | 0.0262 | 0.0645 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0032 | 0.027 | 1 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0015 | 0.008 | 0.0198 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0084 | 0.0876 | 0.2344 |
Echinococcus multilocularis | bloom syndrome protein | 0.0026 | 0.0201 | 0.0201 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0009 | 0.0004 | 0.001 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0084 | 0.0876 | 0.2344 |
Echinococcus multilocularis | 0.001 | 0.0022 | 0.0022 | |
Entamoeba histolytica | Ran family GTPase | 0.0023 | 0.0167 | 0.4758 |
Mycobacterium ulcerans | cytochrome P450 125A7 Cyp125A7 | 0.001 | 0.0022 | 0.0825 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0876 | 0.2344 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0049 | 0.0465 | 0.1244 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0351 | 1 |
Echinococcus multilocularis | Mitotic checkpoint protein PRCC, C terminal | 0.0769 | 0.8777 | 0.8777 |
Schistosoma mansoni | hypothetical protein | 0.0769 | 0.8777 | 0.9002 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0032 | 0.027 | 0.2803 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.001 | 0.0022 | 0.0086 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.004 | 0.0361 | 0.0892 |
Giardia lamblia | Sgs1 DNA helicase, putative | 0.0011 | 0.0026 | 0.096 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0011 | 0.0026 | 0.0269 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0039 | 0.0351 | 0.0359 |
Plasmodium vivax | ADP-dependent DNA helicase RecQ, putative | 0.0018 | 0.0105 | 0.1087 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0032 | 0.027 | 1 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0033 | 0.0287 | 0.0708 |
Brugia malayi | nuclear receptor RXR | 0.004 | 0.0361 | 0.0892 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.001 | 0.0022 | 0.0086 |
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0032 | 0.027 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.001 | 0.0022 | 0.0086 |
Echinococcus granulosus | Smad4 | 0.0009 | 0.0004 | 0.0004 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.001 | 0.0022 | 0.0086 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0194 | 0.7179 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0233 | 0.259 | 1 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.004 | 0.0361 | 0.0412 |
Onchocerca volvulus | Nuclear receptor subfamily 6 group A member 1 homolog | 0.004 | 0.0361 | 0.4129 |
Brugia malayi | Bloom's syndrome protein homolog | 0.0026 | 0.0201 | 0.0497 |
Onchocerca volvulus | 0.0084 | 0.0876 | 1 | |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0084 | 0.0876 | 0.2344 |
Echinococcus granulosus | importin subunit beta 1 | 0.0031 | 0.0262 | 0.0298 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0084 | 0.0876 | 0.216 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0023 | 0.0172 | 0.0425 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0084 | 0.0876 | 0.216 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.001 | 0.0022 | 0.0086 |
Schistosoma mansoni | hypothetical protein | 0.0039 | 0.0351 | 0.0359 |
Echinococcus granulosus | TGF beta signal transducer SmadC | 0.0009 | 0.0004 | 0.0004 |
Brugia malayi | MH2 domain containing protein | 0.0009 | 0.0004 | 0.0009 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0361 | 0.0968 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.008 | 0.0082 |
Schistosoma mansoni | nuclear hormone receptor | 0.0084 | 0.0876 | 0.0898 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.001 | 0.0022 | 0.0086 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0084 | 0.0876 | 0.0898 |
Echinococcus multilocularis | GPCR, family 2 | 0.0015 | 0.008 | 0.008 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0084 | 0.0876 | 0.0876 |
Mycobacterium ulcerans | cytochrome P450 143A3 Cyp143A3 | 0.001 | 0.0022 | 0.0825 |
Plasmodium vivax | glutathione reductase, putative | 0.0092 | 0.0962 | 1 |
Entamoeba histolytica | hypothetical protein | 0.0025 | 0.0194 | 0.5525 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0084 | 0.0876 | 0.0898 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0084 | 0.0876 | 0.0997 |
Giardia lamblia | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0167 | 0.6182 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.001 | 0.0022 | 0.0086 |
Mycobacterium ulcerans | cytochrome P450 191A3 Cyp191A3 | 0.001 | 0.0022 | 0.0825 |
Mycobacterium ulcerans | cytochrome P450 123A3 Cyp123A3 | 0.001 | 0.0022 | 0.0825 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0084 | 0.0876 | 0.0876 |
Entamoeba histolytica | recQ family helicase, putative | 0.0014 | 0.0062 | 0.1775 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.004 | 0.0361 | 0.0968 |
Brugia malayi | conserved hypotetical protein | 0.004 | 0.0361 | 0.0892 |
Brugia malayi | nuclear receptor NHR-67 | 0.004 | 0.0361 | 0.0892 |
Schistosoma mansoni | thyroid hormone receptor | 0.0853 | 0.975 | 1 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0417 | 0.1028 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0092 | 0.0962 | 0.3716 |
Plasmodium falciparum | glutathione reductase | 0.0032 | 0.027 | 0.2803 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.008 | 0.0082 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0019 | 0.0121 | 0.0324 |
Trypanosoma brucei | ATP-dependent DEAD/H DNA helicase recQ, putative | 0.0014 | 0.0062 | 0.0646 |
Echinococcus granulosus | muscleblind protein | 0.0146 | 0.1587 | 0.1808 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.004 | 0.0361 | 0.0361 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0015 | 0.008 | 0.0092 |
Brugia malayi | Nuclear hormone receptor E75 | 0.004 | 0.0361 | 0.0892 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0049 | 0.0465 | 0.1147 |
Schistosoma mansoni | Smad4 | 0.0009 | 0.0004 | 0.0004 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.004 | 0.0361 | 0.0371 |
Echinococcus granulosus | ATP dependent DNA helicase Q5 | 0.0011 | 0.0026 | 0.003 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.001 | 0.0022 | 0.0086 |
Plasmodium falciparum | ATP-dependent DNA helicase Q1 | 0.0011 | 0.0026 | 0.0269 |
Loa Loa (eye worm) | ATP-dependent DNA helicase | 0.0011 | 0.0026 | 0.0069 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0146 | 0.1587 | 0.1587 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.001 | 0.0022 | 0.0086 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0876 | 0.2344 |
Plasmodium falciparum | importin beta, putative | 0.0031 | 0.0262 | 0.2718 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.004 | 0.0361 | 0.0361 |
Brugia malayi | hypothetical protein | 0.0045 | 0.0417 | 0.1028 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0015 | 0.008 | 0.0198 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0004 | 0.0004 |
Brugia malayi | tailless protein | 0.004 | 0.0361 | 0.0892 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0084 | 0.0876 | 0.2344 |
Mycobacterium ulcerans | cytochrome P450 150A6 Cyp150A6 | 0.001 | 0.0022 | 0.0825 |
Brugia malayi | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0167 | 0.0411 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0417 | 0.1115 |
Onchocerca volvulus | 0.004 | 0.0361 | 0.4129 | |
Trypanosoma brucei | Lanosterol 14-alpha demethylase | 0.001 | 0.0022 | 0.0231 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.027 | 0.2803 |
Toxoplasma gondii | ATP-dependent DNA helicase, RecQ family protein | 0.0011 | 0.0026 | 0.0269 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0084 | 0.0876 | 0.0997 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0032 | 0.027 | 0.2803 |
Brugia malayi | Thioredoxin reductase | 0.0092 | 0.0962 | 0.2374 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0023 | 0.0172 | 0.0425 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.004 | 0.0361 | 0.0412 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0032 | 0.027 | 0.0277 |
Trichomonas vaginalis | ran, putative | 0.0023 | 0.0167 | 0.6182 |
Treponema pallidum | NADH oxidase | 0.0032 | 0.027 | 1 |
Echinococcus multilocularis | TGF beta signal transducer SmadC | 0.0009 | 0.0004 | 0.0004 |
Plasmodium falciparum | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0167 | 0.1733 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0129 | 0.1389 | 0.3719 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0039 | 0.0351 | 0.0399 |
Echinococcus granulosus | GPCR family 2 | 0.0015 | 0.008 | 0.0092 |
Schistosoma mansoni | nuclear hormone receptor | 0.004 | 0.0361 | 0.0371 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.0674 | 0.7686 | 0.7686 |
Loa Loa (eye worm) | hypothetical protein | 0.0045 | 0.0417 | 0.1115 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0361 | 0.0968 |
Plasmodium falciparum | ADP-dependent DNA helicase RecQ | 0.0023 | 0.0165 | 0.1716 |
Brugia malayi | steroid hormone receptor | 0.0084 | 0.0876 | 0.216 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.004 | 0.0361 | 0.0371 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0876 | 0.2344 |
Brugia malayi | Cytochrome P450 family protein | 0.0019 | 0.0121 | 0.0299 |
Leishmania major | cytochrome p450-like protein | 0.001 | 0.0022 | 0.0231 |
Brugia malayi | ecdysteroid receptor | 0.0084 | 0.0876 | 0.216 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0121 | 0.0324 |
Schistosoma mansoni | coup transcription factor | 0.0084 | 0.0876 | 0.0898 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0084 | 0.0876 | 0.216 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0084 | 0.0876 | 0.0898 |
Trypanosoma brucei | GTP-binding nuclear protein rtb2, putative | 0.0023 | 0.0167 | 0.1733 |
Toxoplasma gondii | HEAT repeat-containing protein | 0.0031 | 0.0262 | 0.2718 |
Loa Loa (eye worm) | GTP-binding nuclear protein RAN/TC4 | 0.0023 | 0.0167 | 0.0446 |
Loa Loa (eye worm) | hypothetical protein | 0.0315 | 0.3539 | 0.9474 |
Brugia malayi | Cytochrome P450 family protein | 0.001 | 0.0022 | 0.0055 |
Trichomonas vaginalis | Importin beta-1 subunit, putative | 0.0025 | 0.0194 | 0.7179 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0361 | 0.0968 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.032 | 0.3594 | 0.8868 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0084 | 0.0876 | 0.0898 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.001 | 0.0022 | 0.0086 |
Trypanosoma cruzi | importin beta-1 subunit, putative | 0.0025 | 0.0194 | 0.2012 |
Loa Loa (eye worm) | hypothetical protein | 0.0049 | 0.0465 | 0.1244 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0084 | 0.0876 | 0.216 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.032 | 0.3594 | 0.8868 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0019 | 0.0121 | 0.0324 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.001 | 0.0022 | 0.0231 |
Echinococcus multilocularis | snurportin 1 | 0.0332 | 0.3736 | 0.3736 |
Echinococcus granulosus | snurportin 1 | 0.0332 | 0.3736 | 0.4256 |
Trypanosoma cruzi | GTP-binding nuclear protein rtb2, putative | 0.0023 | 0.0167 | 0.1733 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.036 | 0.4053 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0209 | 0.232 | 0.8958 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0084 | 0.0876 | 0.0898 |
Brugia malayi | Smad1 | 0.0009 | 0.0004 | 0.0009 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0853 | 0.975 | 0.975 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0084 | 0.0876 | 0.0898 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0032 | 0.027 | 0.2803 |
Brugia malayi | cytochrome P450 | 0.001 | 0.0022 | 0.0055 |
Mycobacterium ulcerans | cytochrome P450 51B1 Cyp51B1 | 0.001 | 0.0022 | 0.0825 |
Echinococcus granulosus | Mitotic checkpoint protein PRCC C terminal | 0.0769 | 0.8777 | 1 |
Trypanosoma cruzi | cytochrome p450-like protein, putative | 0.001 | 0.0022 | 0.0231 |
Leishmania major | trypanothione reductase | 0.0092 | 0.0962 | 1 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0084 | 0.0876 | 0.216 |
Brugia malayi | glutathione reductase | 0.0092 | 0.0962 | 0.2374 |
Echinococcus granulosus | ATP dependent DNA helicase Q1 | 0.0011 | 0.0026 | 0.003 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0032 | 0.027 | 0.2803 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0084 | 0.0876 | 0.2344 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.0361 | 0.0968 |
Toxoplasma gondii | thioredoxin reductase | 0.0092 | 0.0962 | 1 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.004 | 0.0361 | 0.0412 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0032 | 0.027 | 1 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0032 | 0.027 | 1 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0031 | 0.0262 | 0.2718 |
Loa Loa (eye worm) | nucleolar RNA-associated protein alpha | 0.0332 | 0.3736 | 1 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.001 | 0.0022 | 0.0086 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0015 | 0.008 | 0.0215 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.001 | 0.0022 | 0.0086 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.008 | 0.0082 |
Schistosoma mansoni | blooms syndrome DNA helicase | 0.002 | 0.0139 | 0.0142 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0032 | 0.027 | 1 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0209 | 0.232 | 0.8958 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0084 | 0.0876 | 0.216 |
Loa Loa (eye worm) | glutathione reductase | 0.0092 | 0.0962 | 0.2576 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.027 | 0.2803 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0084 | 0.0876 | 0.216 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0876 | 0.2344 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0015 | 0.008 | 0.0092 |
Brugia malayi | hypothetical protein | 0.0039 | 0.0351 | 0.0865 |
Brugia malayi | nuclear receptor NHR-88 | 0.0084 | 0.0876 | 0.216 |
Toxoplasma gondii | GTP-binding nuclear protein ran/tc4 | 0.0023 | 0.0167 | 0.1733 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.008 | 0.0215 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.027 | 0.2803 |
Echinococcus multilocularis | ATP dependent DNA helicase Q1 | 0.0011 | 0.0026 | 0.0026 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0092 | 0.0962 | 1 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0029 | 0.0237 | 0.0636 |
Loa Loa (eye worm) | hypothetical protein | 0.0084 | 0.0876 | 0.2344 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0084 | 0.0876 | 0.0997 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0084 | 0.0876 | 0.0876 |
Loa Loa (eye worm) | cytochrome P450 | 0.001 | 0.0022 | 0.006 |
Mycobacterium ulcerans | cytochrome P450 144A4 Cyp144A4 | 0.001 | 0.0022 | 0.0825 |
Schistosoma mansoni | importin beta-1 | 0.0031 | 0.0262 | 0.0268 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0084 | 0.0876 | 0.0898 |
Mycobacterium ulcerans | cytochrome P450 126A3 Cyp126A3 | 0.001 | 0.0022 | 0.0825 |
Schistosoma mansoni | hypothetical protein | 0.0332 | 0.3736 | 0.3831 |
Trypanosoma brucei | cytochrome P450, putative | 0.0019 | 0.0121 | 0.1258 |
Schistosoma mansoni | nuclear receptor | 0.004 | 0.0361 | 0.0371 |
Trichomonas vaginalis | DNA helicase recq1, putative | 0.0026 | 0.0201 | 0.7467 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0004 | 0.0004 |
Brugia malayi | nuclear receptor NHR-88 | 0.004 | 0.0361 | 0.0892 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0084 | 0.0876 | 0.216 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0032 | 0.027 | 0.2803 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0084 | 0.0876 | 0.0876 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0233 | 0.259 | 1 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0045 | 0.0417 | 0.0427 |
Loa Loa (eye worm) | hypothetical protein | 0.0011 | 0.0026 | 0.0069 |
Schistosoma mansoni | smad | 0.0009 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.004 | 0.0361 | 0.0968 |
Brugia malayi | MH1 domain containing protein | 0.0009 | 0.0004 | 0.0009 |
Loa Loa (eye worm) | MH1 domain-containing protein | 0.0009 | 0.0004 | 0.001 |
Echinococcus granulosus | microtubule associated protein 2 | 0.0674 | 0.7686 | 0.8756 |
Trypanosoma brucei | importin beta-1 subunit, putative | 0.0031 | 0.0262 | 0.2718 |
Brugia malayi | ATP-dependent DNA helicase, RecQ family protein | 0.0011 | 0.0026 | 0.0064 |
Schistosoma mansoni | microtubule-associated protein tau | 0.0674 | 0.7686 | 0.7883 |
Brugia malayi | ecdysone receptor | 0.004 | 0.0361 | 0.0892 |
Entamoeba histolytica | hypothetical protein | 0.0039 | 0.0351 | 1 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.001 | 0.0022 | 0.0025 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0032 | 0.027 | 0.2803 |
Schistosoma mansoni | smad1 5 8 and | 0.0009 | 0.0004 | 0.0004 |
Echinococcus granulosus | FTZ F1 alpha | 0.0084 | 0.0876 | 0.0997 |
Echinococcus multilocularis | muscleblind protein | 0.0146 | 0.1587 | 0.1587 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.001 | 0.0022 | 0.0231 |
Brugia malayi | nuclear receptor RXR | 0.0045 | 0.0417 | 0.1028 |
Mycobacterium tuberculosis | Probable reductase | 0.0209 | 0.232 | 0.8958 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.004 | 0.0361 | 0.0412 |
Echinococcus multilocularis | Smad4 | 0.0009 | 0.0004 | 0.0004 |
Echinococcus granulosus | smad | 0.0009 | 0.0004 | 0.0004 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0084 | 0.0876 | 0.0997 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0287 | 0.0768 |
Brugia malayi | Cytochrome P450 family protein | 0.0029 | 0.0237 | 0.0586 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0084 | 0.0876 | 0.0876 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.004 | 0.0361 | 0.0412 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0032 | 0.027 | 0.2803 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.001 | 0.0022 | 0.0086 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.001 | 0.0022 | 0.0086 |
Schistosoma mansoni | TGF-beta signal transducer Smad2 | 0.0009 | 0.0004 | 0.0004 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0262 | 0.07 |
Brugia malayi | MH2 domain containing protein | 0.0129 | 0.1389 | 0.3427 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0233 | 0.259 | 1 |
Trypanosoma cruzi | Lanosterol 14-alpha demethylase | 0.001 | 0.0022 | 0.0231 |
Leishmania major | importin beta-1 subunit, putative | 0.0025 | 0.0194 | 0.2012 |
Echinococcus multilocularis | ATP dependent DNA helicase Q5 | 0.0011 | 0.0026 | 0.0026 |
Schistosoma mansoni | hypothetical protein | 0.001 | 0.0022 | 0.0023 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.