Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.0313 | 0.0907 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0016 | 0.0031 | 0.0018 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0026 | 0.0105 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0042 | 0.008 |
Loa Loa (eye worm) | runx1 | 0.0061 | 0.0358 | 0.1004 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.004 | 0.021 | 0.0197 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0116 | 0.0758 | 0.2724 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0074 | 0.0174 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0046 | 0.0248 | 0.0813 |
Echinococcus granulosus | cpg binding protein | 0.0066 | 0.0394 | 0.0381 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.006 | 0.0135 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0037 | 0.0184 | 0.0171 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0026 | 0.0105 | 0.0275 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0016 | 0.0031 | 0.0057 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0026 | 0.0105 | 0.0275 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0026 | 0.0105 | 0.0275 |
Schistosoma mansoni | microtubule-associated protein tau | 0.1391 | 1 | 1 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0026 | 0.0105 | 0.3386 |
Brugia malayi | hypothetical protein | 0.0114 | 0.0746 | 0.2165 |
Onchocerca volvulus | 0.003 | 0.0132 | 0.0383 | |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0016 | 0.0031 | 0.0057 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0019 | 0.0056 | 0.0043 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0109 | 0.0277 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0136 | 0.0903 | 0.2594 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0016 | 0.0031 | 0.0057 |
Loa Loa (eye worm) | oxidoreductase | 0.0026 | 0.0105 | 0.0264 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0042 | 0.0028 |
Mycobacterium ulcerans | 20-beta-hydroxysteroid dehydrogenase FabG3 | 0.0026 | 0.0105 | 0.0275 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.003 | 0.0132 | 0.0377 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0136 | 0.0903 | 0.0891 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0015 | 0.0028 | 0.0015 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0031 | 0.0137 | 0.0124 |
Echinococcus multilocularis | nibrin | 0.0022 | 0.0074 | 0.0061 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0109 | 0.0277 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0027 | 0.0109 | 0.0292 |
Brugia malayi | hypothetical protein | 0.0017 | 0.0036 | 0.0103 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0109 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.006 | 0.0135 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0026 | 0.0105 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0187 | 0.0505 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0109 | 0.0292 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0074 | 0.0213 |
Trypanosoma brucei | trypanothione reductase | 0.0046 | 0.0248 | 1 |
Echinococcus multilocularis | Basic leucine zipper (bZIP) transcription | 0.0114 | 0.0746 | 0.0733 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.002 | 0.006 | 0.0109 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0026 | 0.0105 | 0.0275 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0022 | 0.0074 | 0.0207 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.0109 | 0.0134 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.006 | 0.0135 |
Mycobacterium leprae | POSSIBLE OXIDOREDUCTASE | 0.0026 | 0.0105 | 0.0117 |
Entamoeba histolytica | Activator 1 140 kDa subunit, putative | 0.0022 | 0.0074 | 0.0000033707 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0136 | 0.0903 | 0.0891 |
Mycobacterium ulcerans | hypothetical protein | 0.0027 | 0.0109 | 0.0292 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0042 | 0.001 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0026 | 0.0105 | 0.0275 |
Trypanosoma brucei | oxidoreductase-like protein | 0.003 | 0.0132 | 0.4636 |
Loa Loa (eye worm) | hypothetical protein | 0.0486 | 0.3442 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0026 | 0.0105 | 0.0275 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0104 | 0.0674 | 0.2407 |
Onchocerca volvulus | 0.0022 | 0.0074 | 0.0215 | |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0109 | 0.0315 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0053 | 0.008 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.004 | 0.021 | 0.0179 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.004 | 0.021 | 0.0179 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0053 | 0.008 |
Echinococcus granulosus | nibrin | 0.0022 | 0.0074 | 0.0061 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0046 | 0.0248 | 0.0683 |
Onchocerca volvulus | Alhambra homolog | 0.0031 | 0.0137 | 0.0399 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0046 | 0.0248 | 0.0235 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0022 | 0.0074 | 0.0207 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0384 | 0.2701 | 1 |
Echinococcus granulosus | replication factor c subunit 1 | 0.0022 | 0.0074 | 0.0061 |
Mycobacterium ulcerans | oxidoreductase | 0.0026 | 0.0105 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0074 | 0.0174 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0384 | 0.2701 | 1 |
Leishmania major | trypanothione reductase | 0.0046 | 0.0248 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0074 | 0.0174 |
Echinococcus multilocularis | cpg binding protein | 0.0066 | 0.0394 | 0.0381 |
Leishmania major | oxidoreductase-like protein | 0.003 | 0.0132 | 0.4636 |
Brugia malayi | Muscleblind-like protein | 0.0464 | 0.3282 | 0.9535 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0019 | 0.0056 | 0.0043 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0464 | 0.3282 | 0.3273 |
Echinococcus multilocularis | muscleblind protein | 0.0464 | 0.3282 | 0.3273 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.006 | 0.0135 |
Onchocerca volvulus | 0.0486 | 0.3442 | 1 | |
Echinococcus multilocularis | atpase aaa+ type core atpase aaa type core | 0.0911 | 0.6521 | 0.6516 |
Schistosoma mansoni | hypothetical protein | 0.035 | 0.2455 | 0.2432 |
Toxoplasma gondii | thioredoxin reductase | 0.0046 | 0.0248 | 0.0813 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0022 | 0.0074 | 0.0207 |
Plasmodium vivax | thioredoxin reductase, putative | 0.0046 | 0.0248 | 0.0865 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0888 | 0.6352 | 0.6347 |
Echinococcus multilocularis | peregrin | 0.0031 | 0.0137 | 0.0124 |
Echinococcus granulosus | Basic leucine zipper bZIP transcription | 0.0114 | 0.0746 | 0.0733 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0116 | 0.0758 | 0.2605 |
Entamoeba histolytica | 3-oxoacyl-(acyl-carrier protein) reductase, putative | 0.0026 | 0.0105 | 0.0457 |
Schistosoma mansoni | lozenge | 0.0061 | 0.0358 | 0.0328 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0027 | 0.0109 | 0.0524 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0116 | 0.0758 | 0.2724 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0026 | 0.0105 | 0.0275 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0022 | 0.0074 | 0.0207 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0026 | 0.0105 | 0.3386 |
Mycobacterium leprae | 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI | 0.0026 | 0.0105 | 0.0117 |
Echinococcus granulosus | muscleblind protein | 0.0464 | 0.3282 | 0.3273 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0042 | 0.0119 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0102 | 0.3248 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0016 | 0.0031 | 0.0018 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0053 | 0.008 |
Echinococcus multilocularis | geminin | 0.035 | 0.2455 | 0.2445 |
Brugia malayi | PHD-finger family protein | 0.0031 | 0.0137 | 0.0397 |
Entamoeba histolytica | hypothetical protein | 0.0114 | 0.0746 | 1 |
Brugia malayi | Pax transcription activation domain interacting protein | 0.0022 | 0.0074 | 0.0213 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0046 | 0.0248 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0062 | 0.0368 | 0.1067 |
Toxoplasma gondii | 3-ketoacyl-(acyl-carrier-protein) reductase | 0.0026 | 0.0105 | 0.0275 |
Schistosoma mansoni | jumonji domain containing protein | 0.0079 | 0.0492 | 0.0462 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.002 | 0.006 | 0.0109 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0042 | 0.0119 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0042 | 0.001 |
Trichomonas vaginalis | chromosome transmission fidelity factor, putative | 0.0022 | 0.0074 | 0.0207 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0118 | 0.0772 | 0.2776 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0015 | 0.0028 | 0.0015 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0022 | 0.0074 | 0.1971 |
Brugia malayi | glutathione reductase | 0.0046 | 0.0248 | 0.0719 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.0313 | 0.0872 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.004 | 0.021 | 0.057 |
Brugia malayi | DKFZp564C0469 protein | 0.0022 | 0.0074 | 0.0213 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.0313 | 0.0907 |
Loa Loa (eye worm) | hypothetical protein | 0.0464 | 0.3282 | 0.9534 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0026 | 0.0105 | 0.0275 |
Toxoplasma gondii | ATPase, AAA family protein | 0.0022 | 0.0074 | 0.016 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0109 | 0.0315 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0042 | 0.008 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0031 | 0.0137 | 0.0359 |
Trypanosoma brucei | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0022 | 0.0074 | 0.1971 |
Onchocerca volvulus | 0.0062 | 0.0368 | 0.1069 | |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0026 | 0.0105 | 0.0275 |
Trypanosoma cruzi | oxidoreductase-like protein, putative | 0.003 | 0.0132 | 0.4636 |
Trichomonas vaginalis | hypothetical protein | 0.0384 | 0.2701 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0022 | 0.0074 | 0.0207 |
Loa Loa (eye worm) | hypothetical protein | 0.0486 | 0.3442 | 1 |
Brugia malayi | hypothetical protein | 0.0486 | 0.3442 | 1 |
Echinococcus multilocularis | 3 oxoacyl acyl carrier protein reductase | 0.0026 | 0.0105 | 0.0092 |
Plasmodium vivax | 3-oxoacyl-[acyl-carrier-protein] reductase, putative | 0.0026 | 0.0105 | 0.033 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0026 | 0.0105 | 0.0275 |
Schistosoma mansoni | cpg binding protein | 0.0066 | 0.0394 | 0.0364 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0136 | 0.0903 | 0.0875 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0384 | 0.2701 | 1 |
Chlamydia trachomatis | oxoacy-ACP reductase | 0.0026 | 0.0105 | 0.0275 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.0109 | 0.0524 |
Toxoplasma gondii | LsmAD domain-containing protein | 0.0026 | 0.0102 | 0.0264 |
Loa Loa (eye worm) | hypothetical protein | 0.0052 | 0.0295 | 0.082 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0137 | 0.0106 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0022 | 0.0074 | 0.0207 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0027 | 0.0109 | 0.0292 |
Brugia malayi | topoisomerase | 0.0022 | 0.0074 | 0.0213 |
Trichomonas vaginalis | replication factor C large subunit, putative | 0.0022 | 0.0074 | 0.0207 |
Schistosoma mansoni | chromosome transmission fidelity factor | 0.0022 | 0.0074 | 0.0043 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0384 | 0.2701 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0132 | 0.0875 | 0.0846 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0015 | 0.0028 | 0.0015 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0026 | 0.0102 | 0.3248 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.006 | 0.0135 |
Toxoplasma gondii | poly(ADP-ribose) polymerase catalytic domain-containing protein | 0.0022 | 0.0074 | 0.016 |
Schistosoma mansoni | hypothetical protein | 0.035 | 0.2455 | 0.2432 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0016 | 0.0031 | 0.0047 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.003 | 0.0132 | 0.0377 |
Loa Loa (eye worm) | histone methyltransferase | 0.0019 | 0.0056 | 0.0122 |
Brugia malayi | jmjC domain containing protein | 0.004 | 0.021 | 0.0607 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0116 | 0.0758 | 0.2724 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0016 | 0.0031 | 0.0057 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0026 | 0.0105 | 0.0275 |
Giardia lamblia | Replication factor C, subunit 1 | 0.0022 | 0.0074 | 0.4031 |
Mycobacterium tuberculosis | Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) | 0.0026 | 0.0105 | 0.0275 |
Mycobacterium ulcerans | 3-ketoacyl-ACP reductase | 0.0026 | 0.0105 | 0.0275 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0102 | 0.0319 |
Echinococcus granulosus | jumonji domain containing protein | 0.0042 | 0.0224 | 0.0211 |
Brugia malayi | jmjC domain containing protein | 0.01 | 0.0641 | 0.186 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0187 | 0.0543 |
Loa Loa (eye worm) | retinol dehydrogenase 12 | 0.0026 | 0.0105 | 0.0264 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0022 | 0.0074 | 0.1971 |
Entamoeba histolytica | hypothetical protein | 0.0114 | 0.0746 | 1 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0026 | 0.0105 | 0.0302 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0136 | 0.0903 | 0.0891 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0027 | 0.0109 | 0.0292 |
Chlamydia trachomatis | DNA ligase | 0.0022 | 0.0074 | 0.016 |
Brugia malayi | oxidoreductase, short chain dehydrogenase/reductase family protein | 0.0026 | 0.0105 | 0.0302 |
Brugia malayi | AMP-binding enzyme family protein | 0.0027 | 0.0109 | 0.0315 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0042 | 0.0028 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0042 | 0.0028 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0384 | 0.2701 | 1 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0104 | 0.0674 | 0.2283 |
Schistosoma mansoni | hypothetical protein | 0.0114 | 0.0746 | 0.0717 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0026 | 0.0102 | 0.0319 |
Mycobacterium tuberculosis | Possible oxidoreductase | 0.0026 | 0.0105 | 0.0275 |
Brugia malayi | Thioredoxin reductase | 0.0046 | 0.0248 | 0.0719 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0384 | 0.2701 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0026 | 0.0105 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0464 | 0.3282 | 0.9534 |
Toxoplasma gondii | short chain dehydrogenase family protein, putative | 0.0026 | 0.0105 | 0.0275 |
Brugia malayi | hypothetical protein | 0.0022 | 0.0074 | 0.0213 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.002 | 0.006 | 0.0109 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0137 | 0.0398 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0029 | 0.0126 | 0.0366 |
Trypanosoma cruzi | beta-ketoacyl-ACP reductase | 0.0026 | 0.0105 | 0.3386 |
Plasmodium vivax | glutathione reductase, putative | 0.0046 | 0.0248 | 0.0865 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.003 | 0.0132 | 0.0377 |
Mycobacterium tuberculosis | Probable reductase | 0.0104 | 0.0674 | 0.2407 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0136 | 0.0903 | 0.0875 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0042 | 0.001 |
Plasmodium falciparum | thioredoxin reductase | 0.0046 | 0.0248 | 0.0865 |
Plasmodium vivax | hypothetical protein, conserved | 0.0031 | 0.0137 | 0.0452 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0016 | 0.0031 | 0.0089 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0042 | 0.0028 |
Leishmania major | 3-oxoacyl-ACP reductase, putative | 0.0026 | 0.0105 | 0.3386 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0026 | 0.0102 | 0.0319 |
Trichomonas vaginalis | RNA polymerase II ctd phosphatase, putative | 0.0022 | 0.0074 | 0.0207 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0042 | 0.0224 | 0.0211 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0042 | 0.001 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0042 | 0.0028 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0104 | 0.0674 | 0.2407 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.002 | 0.006 | 0.0165 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0026 | 0.0105 | 0.0275 |
Schistosoma mansoni | dihydropteridine reductase | 0.0026 | 0.0105 | 0.0074 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0026 | 0.0105 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0102 | 0.0255 |
Brugia malayi | hypothetical protein | 0.0026 | 0.0102 | 0.0294 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0031 | 0.0137 | 0.0398 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0026 | 0.0105 | 0.0275 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0187 | 0.0157 |
Wolbachia endosymbiont of Brugia malayi | Short-chain alcohol dehydrogenase family enzyme | 0.0026 | 0.0105 | 0.0275 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0027 | 0.0109 | 0.0524 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0026 | 0.0105 | 0.0275 |
Plasmodium falciparum | glutathione reductase | 0.0016 | 0.0031 | 0.0057 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0031 | 0.0137 | 0.0106 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0074 | 0.0174 |
Loa Loa (eye worm) | glutathione reductase | 0.0046 | 0.0248 | 0.0683 |
Trypanosoma brucei | pteridine reductase 1 | 0.0026 | 0.0105 | 0.3386 |
Schistosoma mansoni | cpg binding protein | 0.0066 | 0.0394 | 0.0364 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0063 | 0.0373 | 0.1047 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0026 | 0.0105 | 0.0275 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.0105 | 0.0264 |
Echinococcus multilocularis | Protein lozenge | 0.0061 | 0.0358 | 0.0346 |
Leishmania major | pteridine reductase 1 | 0.003 | 0.0132 | 0.4636 |
Echinococcus multilocularis | microtubule associated protein 2 | 0.1391 | 1 | 1 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.003 | 0.0132 | 0.0377 |
Entamoeba histolytica | hypothetical protein | 0.0114 | 0.0746 | 1 |
Brugia malayi | ATP dependent DNA ligase C terminal region family protein | 0.0022 | 0.0074 | 0.0213 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0136 | 0.0903 | 0.0891 |
Onchocerca volvulus | 0.0027 | 0.0109 | 0.0318 | |
Onchocerca volvulus | 0.0026 | 0.0105 | 0.0304 | |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0027 | 0.0109 | 0.0134 |
Schistosoma mansoni | topbp1 | 0.0022 | 0.0074 | 0.0043 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0031 | 0.0137 | 0.0124 |
Brugia malayi | Bromodomain containing protein | 0.0031 | 0.0137 | 0.0397 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0109 | 0.0277 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0136 | 0.0903 | 0.0875 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0104 | 0.0674 | 0.2407 |
Treponema pallidum | DNA ligase (lig) | 0.0022 | 0.0074 | 1 |
Plasmodium falciparum | replication factor C subunit 1, putative | 0.0022 | 0.0074 | 0.0216 |
Plasmodium falciparum | acyl-CoA synthetase | 0.002 | 0.006 | 0.0165 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0136 | 0.0903 | 0.2623 |
Wolbachia endosymbiont of Brugia malayi | NAD-dependent DNA ligase, Lig | 0.0022 | 0.0074 | 0.016 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0104 | 0.0674 | 0.2407 |
Plasmodium falciparum | thioredoxin reductase | 0.0016 | 0.0031 | 0.0057 |
Schistosoma mansoni | transcription factor LCR-F1 | 0.0114 | 0.0746 | 0.0717 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0109 | 0.3595 |
Toxoplasma gondii | 2,4-dienoyl CoA reductase 2, peroxisomal family protein | 0.003 | 0.0132 | 0.0377 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0027 | 0.0109 | 0.0292 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0046 | 0.0248 | 0.0235 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0109 | 0.3595 |
Plasmodium falciparum | 3-oxoacyl-[acyl-carrier-protein] reductase | 0.0026 | 0.0105 | 0.033 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0022 | 0.0074 | 0.0207 |
Leishmania major | dehydrogenase/oxidoreductase-like protein | 0.0026 | 0.0105 | 0.3386 |
Loa Loa (eye worm) | 3-hydroxyacyl-CoA dehydrogenase type II | 0.0026 | 0.0105 | 0.0264 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0026 | 0.0105 | 0.0275 |
Entamoeba histolytica | hypothetical protein | 0.0114 | 0.0746 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.0313 | 0.0872 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0104 | 0.0674 | 0.2407 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0384 | 0.2701 | 1 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0026 | 0.0105 | 0.0275 |
Schistosoma mansoni | cpg binding protein | 0.0062 | 0.0368 | 0.0338 |
Mycobacterium ulcerans | short-chain type dehydrogenase/reductase | 0.0026 | 0.0105 | 0.0275 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0025 | 0.0101 | 0.007 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0027 | 0.0109 | 0.3595 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0026 | 0.0105 | 0.0275 |
Echinococcus granulosus | geminin | 0.035 | 0.2455 | 0.2445 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0027 | 0.0109 | 0.0292 |
Mycobacterium ulcerans | 3-oxoacyl-ACP reductase | 0.0026 | 0.0105 | 0.0275 |
Schistosoma mansoni | topbp1 | 0.0022 | 0.0074 | 0.0043 |
Trypanosoma cruzi | FHA domain containing protein, putative | 0.0022 | 0.0074 | 0.1971 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0062 | 0.0368 | 0.1032 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0019 | 0.0053 | 0.008 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0026 | 0.0102 | 0.3248 |
Echinococcus multilocularis | replication factor c subunit 1 | 0.0022 | 0.0074 | 0.0061 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.01 | 0.0641 | 0.0628 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0016 | 0.0031 | 0.0047 |
Plasmodium falciparum | glutathione reductase | 0.0046 | 0.0248 | 0.0865 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0074 | 0.0174 |
Mycobacterium ulcerans | NAD-dependent DNA ligase LigA | 0.0022 | 0.0074 | 0.016 |
Mycobacterium ulcerans | 3-alpha-hydroxysteroid dehydrogenase | 0.003 | 0.0132 | 0.0377 |
Echinococcus granulosus | peregrin | 0.0031 | 0.0137 | 0.0124 |
Mycobacterium tuberculosis | Probable short-chain type dehydrogenase/reductase | 0.0026 | 0.0105 | 0.0275 |
Echinococcus granulosus | dnaJ subfamily B | 0.0888 | 0.6352 | 0.6347 |
Schistosoma mansoni | hypothetical protein | 0.0888 | 0.6352 | 0.634 |
Leishmania major | hypothetical protein, conserved | 0.0026 | 0.0102 | 0.3248 |
Brugia malayi | PHD-finger family protein | 0.0014 | 0.0014 | 0.0039 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0026 | 0.0105 | 0.0275 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0015 | 0.0028 | 0.0015 |
Mycobacterium tuberculosis | Probable dehydrogenase/reductase | 0.0026 | 0.0105 | 0.0275 |
Trypanosoma brucei | beta-ketoacyl-ACP reductase | 0.0026 | 0.0105 | 0.3386 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0042 | 0.0028 |
Mycobacterium tuberculosis | Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) | 0.0026 | 0.0105 | 0.0275 |
Mycobacterium ulcerans | short chain dehydrogenase | 0.0026 | 0.0105 | 0.0275 |
Echinococcus granulosus | 3 oxoacyl acyl carrier protein reductase | 0.0026 | 0.0105 | 0.0092 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0384 | 0.2701 | 1 |
Schistosoma mansoni | DNA ligase IV | 0.0022 | 0.0074 | 0.0043 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0027 | 0.0109 | 0.0292 |
Loa Loa (eye worm) | hypothetical protein | 0.0022 | 0.0074 | 0.0174 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0027 | 0.0109 | 0.0292 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.01 | 0.0641 | 0.0628 |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0137 | 0.0359 |
Trypanosoma cruzi | BRCA1 C Terminus (BRCT) domain containing protein, putative | 0.0022 | 0.0074 | 0.1971 |
Plasmodium falciparum | phd finger protein, putative | 0.0031 | 0.0137 | 0.0452 |
Giardia lamblia | PHD finger protein 15 | 0.0031 | 0.0137 | 1 |
Plasmodium vivax | replication factor C subunit 1, putative | 0.0022 | 0.0074 | 0.0216 |
Schistosoma mansoni | 3-oxoacyl-[ACP] reductase | 0.0026 | 0.0105 | 0.0074 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.