Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | zinc finger protein | 0.0021 | 0.0486 | 0.0592 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1195 | 0.124 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.4299 | 0.58 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.1195 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.1195 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0026 | 0.1195 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.1195 | 1 |
Echinococcus granulosus | zinc finger protein | 0.0021 | 0.0486 | 0.0592 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.1195 | 0.5 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0019 | 0.0166 | 0.5 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.1195 | 0.5 |
Mycobacterium ulcerans | hypothetical protein | 0.0026 | 0.1195 | 1 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.1195 | 0.5 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0026 | 0.1195 | 1 |
Onchocerca volvulus | 0.0026 | 0.1195 | 0.5 | |
Schistosoma mansoni | hypothetical protein | 0.0022 | 0.0667 | 0.0774 |
Loa Loa (eye worm) | hypothetical protein | 0.0077 | 0.9266 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4118 | 0.4413 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1195 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.3712 | 0.3972 |
Schistosoma mansoni | zinc finger protein | 0.0021 | 0.0486 | 0.0546 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0019 | 0.0166 | 0.5 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0019 | 0.0166 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0039 | 0.3293 | 0.4427 |
Loa Loa (eye worm) | hypothetical protein | 0.0026 | 0.1195 | 0.124 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0039 | 0.3293 | 0.4427 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0026 | 0.1195 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0026 | 0.1195 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0024 | 0.0995 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0026 | 0.1195 | 0.5 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0019 | 0.0166 | 0.139 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0022 | 0.0667 | 0.0667 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0024 | 0.0995 | 0.1188 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4299 | 0.5351 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0026 | 0.1195 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0065 | 0.7374 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.4299 | 0.58 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0026 | 0.1195 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.4299 | 0.58 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.4299 | 0.3525 |
Brugia malayi | Bromodomain containing protein | 0.0042 | 0.37 | 0.2845 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0026 | 0.1195 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0024 | 0.0995 | 0.1287 |
Schistosoma mansoni | bromodomain containing protein | 0.0069 | 0.7988 | 1 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0019 | 0.0158 | 0.0114 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.4299 | 0.58 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4299 | 0.5351 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.4299 | 0.4609 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.4299 | 0.5351 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0026 | 0.1195 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0065 | 0.7374 | 1 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0026 | 0.1195 | 1 |
Brugia malayi | PHD-finger family protein | 0.0027 | 0.1401 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0019 | 0.0166 | 0.0123 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0026 | 0.1195 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0046 | 0.4446 | 0.4769 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.