TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 440.449 | Formula: C22H24N4O6
H donors: 2 H acceptors: 3 LogP: 1.28 Rotable bonds: 11
Rule of 5 violations (Lipinski): 1
SMILES: COCCNC(=O)CNC(=O)c1nn(c2ccc(c(c2)OC)OC)c(=O)c2c1cccc2
InChi: 1S/C22H24N4O6/c1-30-11-10-23-19(27)13-24-21(28)20-15-6-4-5-7-16(15)22(29)26(25-20)14-8-9-17(31-2)18(12-14)32-3/h4-9,12H,10-11,13H2,1-3H3,(H,23,27)(H,24,28)
InChiKey: RWBPMRMZLHLMSY-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Trypanosoma brucei	heat shock protein 90, putative	0.0046	0.0469	0.0606
Brugia malayi	amidase	0.0101	0.1426	0.1273
Brugia malayi	Heterochromatin protein 1	0.007	0.0888	0.0726
Brugia malayi	MH2 domain containing protein	0.0124	0.1843	0.1697
Echinococcus granulosus	geminin	0.017	0.2644	0.5732
Schistosoma mansoni	heat shock protein	0.0031	0.0198	0.0053
Trypanosoma brucei	Heat shock protein 83, putative	0.0046	0.0469	0.0606
Mycobacterium leprae	POSSIBLE LYSOPHOSPHOLIPASE	0.0285	0.4666	1
Schistosoma mansoni	heat shock protein	0.0046	0.0469	0.0681
Toxoplasma gondii	Hsp90 domain-containing protein	0.0174	0.2718	1
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0035	0.0283	0.0251
Entamoeba histolytica	heat shock protein 90, putative	0.0046	0.0469	0.0606
Brugia malayi	Hsp90 protein	0.0031	0.0198	0.0023
Trypanosoma brucei	heat shock protein, putative	0.0046	0.0469	0.0606
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.008	0.1066	0.1524
Trypanosoma cruzi	monoglyceride lipase, putative	0.0285	0.4666	1
Brugia malayi	chromobox protein homolog 3	0.0039	0.035	0.0177
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.008	0.1066	0.3578
Echinococcus granulosus	CREB binding protein	0.0275	0.4482	1
Onchocerca volvulus	Serine\/threonine kinase homolog	0.0095	0.1324	1
Mycobacterium tuberculosis	Possible lysophospholipase	0.0285	0.4666	1
Trichomonas vaginalis	Clan SC, family S33, methylesterase-like serine peptidase	0.0285	0.4666	1
Echinococcus multilocularis	heat shock protein 75 kDa, mitochondrial	0.0031	0.0198	0.0053
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.1324	0.2631
Treponema pallidum	ATP-dependent Clp protease proteolytic subunit	0.008	0.1066	1
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0074	0.0963	0.183
Schistosoma mansoni	peptidase Clp (S14 family)	0.008	0.1066	0.2069
Echinococcus multilocularis	endoplasmin	0.0043	0.0419	0.0566
Mycobacterium ulcerans	ATP-dependent Clp protease proteolytic subunit	0.008	0.1066	0.1524
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Echinococcus multilocularis	geminin	0.017	0.2644	0.5732
Schistosoma mansoni	fatty-acid amide hydrolase	0.0101	0.1426	0.2904
Plasmodium vivax	heat shock protein 86, putative	0.0046	0.0469	0.0713
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Echinococcus granulosus	heat shock protein 90	0.0039	0.0352	0.0411
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP)	0.0052	0.0583	0.0385
Mycobacterium leprae	PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G)	0.0043	0.0419	0.0604
Loa Loa (eye worm)	heterochromatin protein 1	0.007	0.0888	0.0726
Schistosoma mansoni	endoplasmin	0.0046	0.0469	0.0681
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Trypanosoma cruzi	polo-like protein kinase, putative	0.0095	0.1324	0.2838
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Schistosoma mansoni	hypothetical protein	0.0074	0.0963	0.183
Echinococcus multilocularis	peptidase Clp (S14 family)	0.0052	0.0583	0.0946
Echinococcus multilocularis	heat shock protein 90	0.0039	0.0352	0.0411
Trypanosoma cruzi	heat shock protein 85, putative	0.0046	0.0469	0.1004
Trichomonas vaginalis	valacyclovir hydrolase, putative	0.0285	0.4666	1
Echinococcus granulosus	chromobox protein 1	0.007	0.0888	0.1655
Toxoplasma gondii	heat shock protein 90, putative	0.0046	0.0469	0.1254
Toxoplasma gondii	heat shock protein 75, putative	0.0031	0.0198	0.0202
Trichomonas vaginalis	Clan SC, family S33, methylesterase-like serine peptidase	0.0285	0.4666	1
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.1324	0.2631
Trichomonas vaginalis	conserved hypothetical protein	0.0285	0.4666	1
Mycobacterium ulcerans	lysophospholipase	0.0285	0.4666	1
Trypanosoma brucei	heat shock protein, putative	0.0046	0.0469	0.0606
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Leishmania major	protein kinase, putative,polo-like protein kinase, putative	0.0095	0.1324	0.2521
Toxoplasma gondii	PHD-finger domain-containing protein	0.0029	0.0175	0.0114
Echinococcus multilocularis	chromobox protein 1	0.007	0.0888	0.1655
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.0096	0.1342	0.271
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.005	0.054	0.0371
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.008	0.1066	0.5
Trypanosoma cruzi	heat shock protein 90, putative	0.0039	0.0352	0.0755
Loa Loa (eye worm)	hypothetical protein	0.0589	1	1
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.1324	0.2631
Echinococcus granulosus	ATP dependent Clp protease proteolytic subunit	0.008	0.1066	0.2069
Schistosoma mansoni	hypothetical protein	0.017	0.2644	0.5732
Trichomonas vaginalis	heat shock protein, putative	0.0043	0.0419	0.0635
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.1324	0.2631
Loa Loa (eye worm)	jmjC domain-containing protein	0.0035	0.0283	0.011
Schistosoma mansoni	amidase	0.0101	0.1426	0.2904
Trypanosoma brucei	heat shock protein, putative	0.0046	0.0469	0.0606
Echinococcus multilocularis	fatty acid amide hydrolase 1	0.0101	0.1426	0.2904
Leishmania major	monoglyceride lipase, putative	0.0285	0.4666	1
Onchocerca volvulus	Heat shock protein 75 kDa, mitochondrial homolog	0.0031	0.0198	0.0197
Giardia lamblia	Heat shock protein HSP 90-alpha	0.0039	0.0352	0.1538
Echinococcus multilocularis	heat shock protein 90	0.0046	0.0469	0.0681
Echinococcus granulosus	heat shock protein 90	0.0046	0.0469	0.0681
Trichomonas vaginalis	chromobox protein, putative	0.007	0.0888	0.167
Trichomonas vaginalis	conserved hypothetical protein	0.0039	0.035	0.0482
Echinococcus multilocularis	fatty acid amide hydrolase 1	0.0101	0.1426	0.2904
Loa Loa (eye worm)	CBP-B	0.0275	0.4482	0.4383
Trichomonas vaginalis	heat shock protein, putative	0.0039	0.0352	0.0487
Wolbachia endosymbiont of Brugia malayi	ATP-dependent Clp protease proteolytic subunit	0.008	0.1066	1
Loa Loa (eye worm)	hypothetical protein	0.008	0.1066	0.0907
Brugia malayi	TAZ zinc finger family protein	0.0275	0.4482	0.4383
Brugia malayi	Calcitonin receptor-like protein seb-1	0.005	0.054	0.0371
Trypanosoma brucei	polo-like protein kinase	0.0095	0.1324	0.2521
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0042	0.0402	0.197
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.0096	0.1342	0.271
Trichomonas vaginalis	Clan SC, family S33, methylesterase-like serine peptidase	0.0285	0.4666	1
Mycobacterium tuberculosis	Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2)	0.0052	0.0583	0.0385
Trypanosoma brucei	heat shock protein, putative	0.0046	0.0469	0.0606
Trichomonas vaginalis	heat shock protein, putative	0.0043	0.0419	0.0635
Toxoplasma gondii	PHD-finger domain-containing protein	0.0029	0.0175	0.0114
Trypanosoma brucei	heat shock protein, putative	0.0046	0.0469	0.0606
Brugia malayi	Probable ClpP-like protease	0.008	0.1066	0.0907
Trichomonas vaginalis	CAMK family protein kinase	0.0047	0.0485	0.0781
Brugia malayi	hypothetical protein	0.0074	0.0963	0.0802
Echinococcus multilocularis	CREB binding protein	0.0275	0.4482	1
Trypanosoma cruzi	heat shock protein 85, putative	0.0046	0.0469	0.1004
Trypanosoma cruzi	heat shock protein 90, putative	0.0046	0.0469	0.1004
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Toxoplasma gondii	heat shock protein HSP90	0.0046	0.0469	0.1254
Trypanosoma cruzi	heat shock protein, putative	0.0031	0.0198	0.0424
Schistosoma mansoni	CREB-binding protein 2	0.0275	0.4482	1
Entamoeba histolytica	hydrolase, alpha/beta fold family domain containing protein	0.0285	0.4666	1
Plasmodium falciparum	lysophospholipase, putative	0.0285	0.4666	1
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0035	0.0283	0.0251
Echinococcus multilocularis	chromobox protein 1	0.007	0.0888	0.1655
Plasmodium vivax	endoplasmin, putative	0.0046	0.0469	0.0713
Treponema pallidum	heat shock protein 90	0.0043	0.0419	0.2966
Trypanosoma cruzi	Heat shock protein 83, putative	0.0046	0.0469	0.1004
Loa Loa (eye worm)	MH2 domain-containing protein	0.0124	0.1843	0.1697
Plasmodium falciparum	lysophospholipase, putative	0.0285	0.4666	1
Echinococcus granulosus	jumonji domain containing protein	0.0041	0.0376	0.0467
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.1324	0.2631
Loa Loa (eye worm)	transcription factor SMAD2	0.0124	0.1843	0.1697
Echinococcus multilocularis	ATP dependent Clp protease proteolytic subunit	0.008	0.1066	0.2069
Trypanosoma brucei	heat shock protein 90, putative	0.0046	0.0469	0.0606
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Loa Loa (eye worm)	hypothetical protein	0.005	0.054	0.0371
Entamoeba histolytica	heat shock protein 90, putative	0.0046	0.0469	0.0606
Echinococcus granulosus	heat shock protein 75 kDa mitochondrial	0.0031	0.0198	0.0053
Entamoeba histolytica	hydrolase, alpha/beta fold family domain containing protein	0.0285	0.4666	1
Loa Loa (eye worm)	heat shock protein 90	0.0046	0.0469	0.0298
Trichomonas vaginalis	Clan SC, family S33, methylesterase-like serine peptidase	0.0285	0.4666	1
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.1324	0.2631
Loa Loa (eye worm)	endoplasmin	0.0046	0.0469	0.0298
Trichomonas vaginalis	Clan SC, family S33, methylesterase-like serine peptidase	0.0285	0.4666	1
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.008	0.1066	0.2062
Giardia lamblia	Grp94/Hsp90	0.0043	0.0419	0.2121
Onchocerca volvulus		0.0031	0.0201	0.0224
Schistosoma mansoni	jumonji domain containing protein	0.0076	0.0997	0.1908
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Trichomonas vaginalis	chromobox protein, putative	0.007	0.0888	0.167
Trichomonas vaginalis	chromobox protein, putative	0.0042	0.0402	0.0597
Brugia malayi	serine/threonine-protein kinase plk-2	0.0095	0.1324	0.1169
Plasmodium falciparum	ATP-dependent Clp protease proteolytic subunit	0.0028	0.0146	0.0033
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.005	0.054	0.0371
Plasmodium vivax	hypothetical protein, conserved	0.0029	0.0175	0.0065
Leishmania major	lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative	0.0043	0.0419	0.0495
Entamoeba histolytica	serine/threonine protein kinase, putative	0.0095	0.1324	0.2521
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Trypanosoma brucei	heat shock protein, putative	0.0046	0.0469	0.0606
Schistosoma mansoni	serine/threonine protein kinase	0.0095	0.1324	0.2668
Plasmodium vivax	heat shock protein 90, putative	0.0031	0.0198	0.0115
Trypanosoma brucei	heat shock protein, putative	0.0046	0.0469	0.0606
Schistosoma mansoni	CREB-binding protein 1 (SmCBP1)	0.0275	0.4482	1
Echinococcus granulosus	endoplasmin	0.0043	0.0419	0.0566
Loa Loa (eye worm)	PLK/PLK1 protein kinase	0.0095	0.1324	0.1169
Onchocerca volvulus	Heterochromatin protein 1 homolog	0.0039	0.035	0.1516
Echinococcus granulosus	heat shock protein heat shock protein 90 alpha	0.0039	0.0352	0.0411
Schistosoma mansoni	hypothetical protein	0.017	0.2644	0.5732
Brugia malayi	heat shock protein 90	0.0046	0.0469	0.0298
Trichomonas vaginalis	CAMK family protein kinase	0.0047	0.0485	0.0781
Trichomonas vaginalis	conserved hypothetical protein	0.0028	0.0149	0.0039
Plasmodium falciparum	esterase, putative	0.0285	0.4666	1
Trichomonas vaginalis	CAMK family protein kinase	0.0095	0.1324	0.2631
Trypanosoma cruzi	heat shock protein 85, putative	0.0046	0.0469	0.1004
Trypanosoma brucei	heat shock protein, putative	0.0046	0.0469	0.0606
Echinococcus granulosus	fatty acid amide hydrolase 1	0.0101	0.1426	0.2904
Trichomonas vaginalis	conserved hypothetical protein	0.0028	0.0149	0.0039
Giardia lamblia	Heat shock protein HSP 90-alpha	0.0046	0.0469	0.2552
Plasmodium falciparum	phd finger protein, putative	0.0029	0.0175	0.0098
Brugia malayi	Endoplasmin precursor	0.0046	0.0469	0.0298
Brugia malayi	latrophilin 2 splice variant baaae	0.0034	0.0262	0.0088
Brugia malayi	jmjC domain containing protein	0.0035	0.0283	0.011
Trypanosoma brucei	monoglyceride lipase, putative	0.0285	0.4666	1
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2)	0.008	0.1066	0.2036
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Echinococcus multilocularis	heat shock protein	0.0046	0.0469	0.0681
Trichomonas vaginalis	endoplasmin, putative	0.0033	0.0248	0.0257
Plasmodium falciparum	lysophospholipase, putative	0.0285	0.4666	1
Echinococcus granulosus	serine:threonine protein kinase PLK1	0.0095	0.1324	0.2668
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Loa Loa (eye worm)	hypothetical protein	0.0101	0.1426	0.1273
Loa Loa (eye worm)	hypothetical protein	0.0031	0.0201	0.0026
Loa Loa (eye worm)	hypothetical protein	0.0034	0.0262	0.0088
Plasmodium vivax	ATP-dependent Clp protease proteolytic subunit, putative	0.008	0.1066	0.2036
Echinococcus granulosus	fatty acid amide hydrolase 1	0.0101	0.1426	0.2904
Plasmodium vivax	PST-A protein	0.0285	0.4666	1
Plasmodium vivax	heat shock protein, putative	0.0174	0.2718	0.569
Trypanosoma cruzi	polo-like protein kinase, putative	0.0095	0.1324	0.2838
Loa Loa (eye worm)	jmjC domain-containing protein	0.006	0.0722	0.0556
Chlamydia trachomatis	ATP-dependent Clp protease proteolytic subunit	0.008	0.1066	0.5
Schistosoma mansoni	heat shock protein	0.0046	0.0469	0.0681
Echinococcus multilocularis	lysine specific demethylase 5A	0.0035	0.0283	0.0251
Schistosoma mansoni	hypothetical protein	0.0034	0.0262	0.0201
Mycobacterium ulcerans	hypothetical protein	0.0285	0.4666	1
Trichomonas vaginalis	conserved hypothetical protein	0.0039	0.035	0.0482
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Echinococcus granulosus	CREB binding protein	0.0275	0.4482	1
Schistosoma mansoni	chromobox protein	0.007	0.0888	0.1655
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0074	0.0963	0.183
Trichomonas vaginalis	heat shock protein, putative	0.0046	0.0469	0.0744
Trypanosoma brucei	monoglyceride lipase, putative	0.0285	0.4666	1
Entamoeba histolytica	hypothetical protein	0.0074	0.0963	0.1713
Entamoeba histolytica	hypothetical protein	0.0074	0.0963	0.1713
Giardia lamblia	Kinase, PLK	0.0095	0.1324	1
Echinococcus granulosus	lysine specific demethylase 5A	0.0035	0.0283	0.0251
Loa Loa (eye worm)	hypothetical protein	0.005	0.0542	0.0373
Schistosoma mansoni	transcription factor LCR-F1	0.0074	0.0963	0.183
Trichomonas vaginalis	conserved hypothetical protein	0.0285	0.4666	1
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Echinococcus multilocularis	jumonji domain containing protein	0.0041	0.0376	0.0467
Schistosoma mansoni	endoplasmin	0.0046	0.0469	0.0681
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Trichomonas vaginalis	heat shock protein, putative	0.0033	0.0248	0.0257
Mycobacterium leprae	PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP)	0.0052	0.0583	0.0966
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Schistosoma mansoni	chromobox protein	0.007	0.0888	0.1655
Entamoeba histolytica	hypothetical protein	0.0074	0.0963	0.1713
Schistosoma mansoni	kinase	0.0048	0.0507	0.077
Trypanosoma cruzi	heat shock protein 85, putative	0.0039	0.0352	0.0755
Leishmania major	heat shock protein 83-1	0.0046	0.0469	0.0606
Loa Loa (eye worm)	hypothetical protein	0.0039	0.035	0.0177
Echinococcus granulosus	chromobox protein 1	0.007	0.0888	0.1655
Brugia malayi	jmjC domain containing protein	0.0096	0.1342	0.1188
Plasmodium falciparum	heat shock protein 90	0.0046	0.0469	0.0744
Loa Loa (eye worm)	heat shock protein 75	0.0031	0.0198	0.0023
Echinococcus granulosus	peptidase Clp S14 family	0.0052	0.0583	0.0946
Plasmodium falciparum	heat shock protein 90, putative	0.0174	0.2718	0.5704
Toxoplasma gondii	ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein	0.008	0.1066	0.3578
Echinococcus granulosus	heat shock protein	0.0046	0.0469	0.0681
Plasmodium falciparum	endoplasmin, putative	0.0033	0.0248	0.0257
Echinococcus multilocularis	serine:threonine protein kinase PLK1	0.0095	0.1324	0.2668
Trichomonas vaginalis	chromobox protein, putative	0.0042	0.0402	0.0597
Entamoeba histolytica	hypothetical protein	0.0074	0.0963	0.1713

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 788169