Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | adenosine deaminase | 0.0166 | 1 | 1 |
Trypanosoma cruzi | adenosine monophosphate deaminase-like protein, putative | 0.0054 | 0 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.5169 | 0.5169 |
Mycobacterium leprae | Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) | 0.0166 | 1 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Onchocerca volvulus | Adenosine deaminase homolog | 0.0166 | 1 | 1 |
Leishmania major | adenine aminohydrolase | 0.0166 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase 2, putative | 0.0054 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.5169 | 0.5169 |
Trypanosoma brucei | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Trypanosoma brucei | adenosine monophosphate deaminase, putative | 0.0054 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.5169 | 0.5169 |
Plasmodium falciparum | adenosine deaminase | 0.0166 | 1 | 1 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0166 | 1 | 1 |
Mycobacterium tuberculosis | Probable adenosine deaminase Add (adenosine aminohydrolase) | 0.0166 | 1 | 0.5 |
Trypanosoma brucei | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Mycobacterium ulcerans | adenosine deaminase | 0.0166 | 1 | 0.5 |
Trypanosoma cruzi | adenosine monophosphate deaminase, putative | 0.0054 | 0 | 0.5 |
Toxoplasma gondii | Adenosine/AMP deaminase domain-containing protein | 0.0166 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0166 | 1 | 1 |
Trypanosoma cruzi | AMP deaminase, putative | 0.0054 | 0 | 0.5 |
Schistosoma mansoni | adenosine deaminase-related | 0.0166 | 1 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0166 | 1 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0112 | 0.5169 | 0.5169 |
Echinococcus granulosus | adenosine deaminase | 0.0166 | 1 | 1 |
Plasmodium vivax | adenosine deaminase, putative | 0.0166 | 1 | 1 |
Trichomonas vaginalis | adenosine deaminase, putative | 0.0166 | 1 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0166 | 1 | 1 |
Treponema pallidum | adenosine deaminase | 0.0166 | 1 | 0.5 |
Entamoeba histolytica | adenosine deaminase, putative | 0.0166 | 1 | 1 |
Schistosoma mansoni | adenosine deaminase | 0.0166 | 1 | 1 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
ID50 (functional) | > 100 ug kg-1 | Compound was evaluated for antisecretion activity using stomach perfusion test in the anesthetized rat (ig administration) | ChEMBL. | 3761303 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
1 literature reference was collected for this gene.