Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Mycobacterium tuberculosis | Cytochrome P450 51 Cyp51 (CYPL1) (P450-L1A1) (sterol 14-alpha demethylase) (lanosterol 14-alpha demethylase) (P450-14DM) | 0.0014 | 0.0084 | 0.1351 |
Onchocerca volvulus | 0.0027 | 0.0387 | 0.2429 | |
Schistosoma mansoni | lamin | 0.0027 | 0.0387 | 0.1062 |
Brugia malayi | Intermediate filament tail domain containing protein | 0.0027 | 0.0387 | 0.0374 |
Schistosoma mansoni | lamin | 0.0027 | 0.0387 | 0.1062 |
Toxoplasma gondii | cytochrome p450 superfamily protein | 0.0014 | 0.0084 | 0.0832 |
Echinococcus multilocularis | geminin | 0.0166 | 0.3531 | 0.3523 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0231 | 0.0218 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.002 | 0.0231 | 0.0218 |
Mycobacterium tuberculosis | Probable cytochrome P450 138 Cyp138 | 0.0014 | 0.0084 | 0.1351 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD | 0.0025 | 0.0339 | 0.4755 |
Echinococcus multilocularis | 0.0014 | 0.0084 | 0.0071 | |
Loa Loa (eye worm) | hypothetical protein | 0.0031 | 0.0481 | 0.0468 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.002 | 0.0231 | 0.0218 |
Mycobacterium leprae | PROBABLE THIOESTERASE TESA | 0.0021 | 0.0244 | 0.2987 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0133 | 0.278 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 140 Cyp140 | 0.0014 | 0.0084 | 0.1351 |
Echinococcus multilocularis | survival motor neuron protein 1 | 0.0238 | 0.518 | 0.5174 |
Loa Loa (eye worm) | hypothetical protein | 0.0238 | 0.518 | 0.5174 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0231 | 0.0218 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.002 | 0.0231 | 0.0618 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.02 | 0.0531 |
Echinococcus granulosus | GPCR family 2 | 0.0031 | 0.0481 | 0.0468 |
Brugia malayi | RNA binding protein | 0.0128 | 0.2664 | 0.2654 |
Mycobacterium ulcerans | thioesterase | 0.0021 | 0.0244 | 0.2987 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0231 | 0.0218 |
Loa Loa (eye worm) | RNA binding protein | 0.0128 | 0.2664 | 0.2654 |
Mycobacterium leprae | Probable polyketide synthase Pks1 | 0.0027 | 0.0375 | 0.5413 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0231 | 0.0618 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.0339 | 0.4755 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0089 | 0.0076 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.002 | 0.0231 | 0.0218 |
Brugia malayi | cytoplasmic intermediate filament protein | 0.0015 | 0.01 | 0.0087 |
Mycobacterium tuberculosis | Probable cytochrome P450 130 Cyp130 | 0.0014 | 0.0084 | 0.1351 |
Echinococcus multilocularis | cytoplasmic intermediate filament protein | 0.0013 | 0.0067 | 0.0054 |
Loa Loa (eye worm) | tyrosyl-DNA phosphodiesterase | 0.0133 | 0.278 | 0.2771 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0116 | 0.2409 | 0.2399 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0481 | 0.1329 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0022 | 0.0278 | 0.0721 |
Echinococcus multilocularis | tyrosyl DNA phosphodiesterase 1 | 0.0133 | 0.278 | 0.2771 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.3531 | 1 |
Trypanosoma cruzi | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0133 | 0.278 | 1 |
Echinococcus granulosus | geminin | 0.0166 | 0.3531 | 0.3523 |
Echinococcus granulosus | muscleblind protein | 0.0451 | 1 | 1 |
Brugia malayi | TAR-binding protein | 0.0128 | 0.2664 | 0.2654 |
Echinococcus multilocularis | lamin dm0 | 0.0027 | 0.0387 | 0.0374 |
Mycobacterium tuberculosis | Possible cytochrome P450 135B1 Cyp135B1 | 0.0014 | 0.0084 | 0.1351 |
Mycobacterium ulcerans | multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0027 | 0.0375 | 0.5413 |
Loa Loa (eye worm) | hypothetical protein | 0.0451 | 1 | 1 |
Loa Loa (eye worm) | AMP-binding enzyme family protein | 0.0023 | 0.0302 | 0.0289 |
Schistosoma mansoni | hypothetical protein | 0.0049 | 0.0873 | 0.2445 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0099 | 0.2017 | 0.2006 |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0018 | 0.0175 | 0.3708 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0031 | 0.0481 | 0.0468 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.002 | 0.0231 | 0.0218 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0099 | 0.2017 | 0.2006 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.002 | 0.0231 | 0.0218 |
Mycobacterium tuberculosis | Probable cytochrome P450 132 Cyp132 | 0.0014 | 0.0084 | 0.1351 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.02 | 0.043 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.02 | 0.322 |
Schistosoma mansoni | hypothetical protein | 0.0166 | 0.3531 | 1 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.02 | 0.043 |
Loa Loa (eye worm) | TAR-binding protein | 0.0128 | 0.2664 | 0.2654 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.0339 | 0.4755 |
Loa Loa (eye worm) | hypothetical protein | 0.0068 | 0.1306 | 0.1294 |
Brugia malayi | cytochrome P450 | 0.0014 | 0.0084 | 0.0071 |
Schistosoma mansoni | intermediate filament proteins | 0.0027 | 0.0387 | 0.1062 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0481 | 0.0468 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0031 | 0.0481 | 0.0468 |
Schistosoma mansoni | coup transcription factor | 0.002 | 0.0231 | 0.0618 |
Mycobacterium tuberculosis | Probable cytochrome P450 136 Cyp136 | 0.0014 | 0.0084 | 0.1351 |
Loa Loa (eye worm) | hypothetical protein | 0.0099 | 0.2017 | 0.2006 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0231 | 0.0218 |
Loa Loa (eye worm) | fatty acid synthase | 0.0025 | 0.0332 | 0.0319 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0231 | 0.0218 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.002 | 0.0231 | 0.0218 |
Mycobacterium tuberculosis | Probable cytochrome P450 141 Cyp141 | 0.0014 | 0.0084 | 0.1351 |
Mycobacterium tuberculosis | Probable multifunctional mycocerosic acid synthase membrane-associated Mas | 0.0027 | 0.0375 | 0.6033 |
Schistosoma mansoni | hypothetical protein | 0.0068 | 0.1306 | 0.3674 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.02 | 0.5 |
Mycobacterium tuberculosis | Probable cytochrome P450 144 Cyp144 | 0.0014 | 0.0084 | 0.1351 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0231 | 0.0218 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.02 | 0.0187 |
Brugia malayi | MH2 domain containing protein | 0.0116 | 0.2409 | 0.2399 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0231 | 0.0218 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.002 | 0.0231 | 0.0218 |
Trypanosoma cruzi | cytochrome P450, putative | 0.0022 | 0.0278 | 0.0721 |
Brugia malayi | hypothetical protein | 0.0238 | 0.518 | 0.5174 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.002 | 0.0231 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.0727 | 0.0714 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.002 | 0.0231 | 0.0218 |
Mycobacterium leprae | Probable multifunctional mycocerosic acid synthase membrane associated enzyme Mas | 0.0027 | 0.0375 | 0.5413 |
Echinococcus multilocularis | musashi | 0.0027 | 0.0387 | 0.0374 |
Loa Loa (eye worm) | intermediate filament tail domain-containing protein | 0.0027 | 0.0387 | 0.0374 |
Mycobacterium ulcerans | polyketide synthase | 0.0027 | 0.0375 | 0.5413 |
Mycobacterium ulcerans | polyketide synthase | 0.0025 | 0.0339 | 0.4755 |
Mycobacterium tuberculosis | Probable cytochrome P450 124 Cyp124 | 0.0014 | 0.0084 | 0.1351 |
Leishmania major | tyrosyl-DNA phosphodiesterase 1 | 0.0133 | 0.278 | 1 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.002 | 0.0231 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0067 | 0.0054 |
Echinococcus granulosus | tyrosyl DNA phosphodiesterase 1 | 0.0133 | 0.278 | 0.2771 |
Echinococcus granulosus | intermediate filament protein | 0.0027 | 0.0387 | 0.0374 |
Loa Loa (eye worm) | cytochrome P450 | 0.0014 | 0.0084 | 0.0071 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks7 | 0.0027 | 0.0375 | 0.6033 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.002 | 0.0231 | 0.0218 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0481 | 0.0468 |
Echinococcus multilocularis | lamin | 0.0027 | 0.0387 | 0.0374 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0099 | 0.2017 | 0.2006 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0056 | 0.0043 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0031 | 0.0481 | 0.0468 |
Brugia malayi | intermediate filament protein | 0.0027 | 0.0387 | 0.0374 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0025 | 0.0339 | 0.5463 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0231 | 0.0218 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.002 | 0.0231 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.0451 | 1 | 1 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.002 | 0.0231 | 0.0218 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.02 | 0.043 |
Echinococcus multilocularis | transcription factor Dp 1 | 0.0077 | 0.1512 | 0.1501 |
Trypanosoma brucei | cytochrome P450, putative | 0.0022 | 0.0278 | 0.0721 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0128 | 0.2664 | 0.2654 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.002 | 0.0231 | 0.0218 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.002 | 0.0231 | 0.0618 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.002 | 0.0231 | 0.0218 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0022 | 0.0278 | 0.0266 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.2664 | 0.7535 |
Brugia malayi | AMP-binding enzyme family protein | 0.0023 | 0.0302 | 0.0289 |
Brugia malayi | Cytochrome P450 family protein | 0.0014 | 0.0084 | 0.0071 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0231 | 0.0218 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0231 | 0.0218 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0231 | 0.0218 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsB | 0.002 | 0.0228 | 0.2682 |
Loa Loa (eye worm) | hypothetical protein | 0.0013 | 0.0056 | 0.0043 |
Mycobacterium tuberculosis | Possible cytochrome P450 126 Cyp126 | 0.0014 | 0.0084 | 0.1351 |
Echinococcus multilocularis | GPCR, family 2 | 0.0031 | 0.0481 | 0.0468 |
Mycobacterium tuberculosis | Probable cytochrome P450 123 Cyp123 | 0.0014 | 0.0084 | 0.1351 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.02 | 0.0531 |
Brugia malayi | Cytochrome P450 family protein | 0.0033 | 0.0507 | 0.0495 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0375 | 0.0363 |
Schistosoma mansoni | cytochrome P450 | 0.0014 | 0.0084 | 0.0201 |
Loa Loa (eye worm) | acyl carrier protein | 0.0012 | 0.0032 | 0.0018 |
Loa Loa (eye worm) | CYP4Cod1 | 0.0022 | 0.0278 | 0.0266 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA | 0.0025 | 0.0339 | 0.4755 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0231 | 0.0218 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0451 | 1 | 1 |
Echinococcus granulosus | survival motor neuron protein 1 | 0.0238 | 0.518 | 0.5174 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.02 | 0.2161 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.002 | 0.0228 | 0.2682 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB | 0.002 | 0.0228 | 0.2682 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.02 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0231 | 0.0218 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.002 | 0.0231 | 0.0618 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.02 | 0.5 |
Schistosoma mansoni | tyrosyl-DNA phosphodiesterase | 0.0133 | 0.278 | 0.7865 |
Echinococcus granulosus | cytoplasmic intermediate filament protein | 0.0013 | 0.0067 | 0.0054 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.002 | 0.0231 | 0.0218 |
Mycobacterium tuberculosis | Probable cytochrome P450 143 Cyp143 | 0.0014 | 0.0084 | 0.1351 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.002 | 0.0231 | 0.0218 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0481 | 0.1329 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsD | 0.0025 | 0.0339 | 0.4755 |
Mycobacterium tuberculosis | Cytochrome P450 121 Cyp121 | 0.0014 | 0.0084 | 0.1351 |
Mycobacterium tuberculosis | Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) | 0.0023 | 0.0302 | 0.4861 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0022 | 0.0278 | 0.0266 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.002 | 0.0231 | 0.0218 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.02 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.002 | 0.0231 | 0.0218 |
Mycobacterium tuberculosis | Probable cytochrome P450 139 Cyp139 | 0.0014 | 0.0084 | 0.1351 |
Mycobacterium tuberculosis | Polyketide synthase Pks2 | 0.0024 | 0.0322 | 0.5182 |
Mycobacterium ulcerans | cytochrome P450 185A4 Cyp185A4 | 0.0022 | 0.0278 | 0.3622 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0231 | 0.0218 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.2664 | 0.7535 |
Mycobacterium ulcerans | polyketide synthase Pks13 | 0.0038 | 0.0621 | 1 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0116 | 0.2409 | 0.2399 |
Mycobacterium tuberculosis | Probable cytochrome P450 monooxygenase 142 Cyp142 | 0.0014 | 0.0084 | 0.1351 |
Onchocerca volvulus | 0.0044 | 0.0761 | 0.8254 | |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.002 | 0.0231 | 0.0218 |
Brugia malayi | oxidoreductase, zinc-binding dehydrogenase family protein | 0.0048 | 0.0849 | 0.0837 |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.0278 | 0.0266 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.002 | 0.0231 | 0.0218 |
Onchocerca volvulus | 0.0027 | 0.0387 | 0.2429 | |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.002 | 0.0231 | 0.0218 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks1 | 0.0018 | 0.0179 | 0.288 |
Echinococcus granulosus | cytochrome P450 2K1 | 0.0014 | 0.0084 | 0.0071 |
Mycobacterium ulcerans | polyketide synthase Pks9 | 0.0017 | 0.0146 | 0.1162 |
Brugia malayi | ecdysteroid receptor | 0.002 | 0.0231 | 0.0218 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.002 | 0.0231 | 0.0218 |
Onchocerca volvulus | 0.0049 | 0.0873 | 1 | |
Toxoplasma gondii | type I fatty acid synthase, putative | 0.0027 | 0.0375 | 1 |
Mycobacterium tuberculosis | Probable membrane bound polyketide synthase Pks6 | 0.0038 | 0.0621 | 1 |
Entamoeba histolytica | tyrosyl-DNA phosphodiesterase, putative | 0.0133 | 0.278 | 1 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.002 | 0.0231 | 0.0618 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0031 | 0.0481 | 0.0468 |
Echinococcus granulosus | FTZ F1 alpha | 0.002 | 0.0231 | 0.0218 |
Toxoplasma gondii | beta-ketoacyl synthase, N-terminal domain-containing protein | 0.0016 | 0.0139 | 0.2574 |
Brugia malayi | nuclear receptor NHR-88 | 0.002 | 0.0231 | 0.0218 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.002 | 0.0231 | 0.0218 |
Echinococcus granulosus | tar DNA binding protein | 0.0128 | 0.2664 | 0.2654 |
Echinococcus multilocularis | tar DNA binding protein | 0.0128 | 0.2664 | 0.2654 |
Brugia malayi | Beta-ketoacyl synthase, N-terminal domain containing protein | 0.0025 | 0.0339 | 0.0327 |
Mycobacterium tuberculosis | Polyketide synthase Pks12 | 0.0027 | 0.0375 | 0.6033 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.02 | 0.043 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.002 | 0.0231 | 0.0218 |
Mycobacterium tuberculosis | Probable cytochrome P450 128 Cyp128 | 0.0014 | 0.0084 | 0.1351 |
Loa Loa (eye worm) | hypothetical protein | 0.0027 | 0.0387 | 0.0374 |
Onchocerca volvulus | Fatty acid synthase homolog | 0.0045 | 0.0796 | 0.8805 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.002 | 0.0231 | 0.0618 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.002 | 0.0231 | 0.0218 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.002 | 0.0231 | 0.0218 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0231 | 0.0218 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.02 | 0.5 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks5 | 0.0024 | 0.0322 | 0.5182 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.002 | 0.0231 | 0.0218 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsA | 0.0025 | 0.0339 | 0.5463 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.02 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.002 | 0.0231 | 0.0218 |
Echinococcus multilocularis | FTZ F1 alpha | 0.002 | 0.0231 | 0.0218 |
Mycobacterium ulcerans | Type I modular polyketide synthase | 0.0025 | 0.0339 | 0.4755 |
Mycobacterium tuberculosis | Possible cytochrome P450 135A1 Cyp135A1 | 0.0014 | 0.0084 | 0.1351 |
Echinococcus granulosus | lamin dm0 | 0.0027 | 0.0387 | 0.0374 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.02 | 0.4492 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0031 | 0.0481 | 0.0468 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0481 | 0.1329 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.002 | 0.0231 | 0.0618 |
Schistosoma mansoni | nuclear hormone receptor | 0.002 | 0.0231 | 0.0618 |
Schistosoma mansoni | hypothetical protein | 0.0031 | 0.0481 | 0.1329 |
Leishmania major | cytochrome p450-like protein | 0.0022 | 0.0278 | 0.0721 |
Echinococcus multilocularis | muscleblind protein | 0.0451 | 1 | 1 |
Mycobacterium ulcerans | thioesterase TesA | 0.0021 | 0.0244 | 0.2987 |
Mycobacterium tuberculosis | Probable polyketide synthase Pks9 | 0.0014 | 0.0093 | 0.1505 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0068 | 0.1306 | 0.1294 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.2664 | 0.7535 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.002 | 0.0231 | 0.0218 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.02 | 0.0187 |
Mycobacterium tuberculosis | Probable cytochrome P450 137 Cyp137 | 0.0014 | 0.0084 | 0.1351 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0128 | 0.2664 | 0.2654 |
Mycobacterium tuberculosis | Probable thioesterase TesA | 0.0021 | 0.0244 | 0.3934 |
Loa Loa (eye worm) | intermediate filament protein | 0.0027 | 0.0387 | 0.0374 |
Echinococcus granulosus | transcription factor Dp 1 | 0.0077 | 0.1512 | 0.1501 |
Schistosoma mansoni | thyroid hormone receptor | 0.002 | 0.0231 | 0.0618 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.002 | 0.0231 | 0.0618 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE | 0.0017 | 0.0146 | 0.1162 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.002 | 0.0231 | 0.0618 |
Mycobacterium leprae | PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC | 0.0027 | 0.0375 | 0.5413 |
Loa Loa (eye worm) | cytochrome P450 family protein | 0.0033 | 0.0507 | 0.0495 |
Mycobacterium tuberculosis | Phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0025 | 0.0339 | 0.5463 |
Brugia malayi | nuclear hormone receptor | 0.002 | 0.0231 | 0.0218 |
Schistosoma mansoni | survival motor neuron protein | 0.0049 | 0.0873 | 0.2445 |
Schistosoma mansoni | hypothetical protein | 0.0014 | 0.0084 | 0.0201 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.02 | 0.0187 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.2664 | 0.7535 |
Loa Loa (eye worm) | cytoplasmic intermediate filament protein | 0.0015 | 0.01 | 0.0087 |
Brugia malayi | steroid hormone receptor | 0.002 | 0.0231 | 0.0218 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.02 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.002 | 0.0231 | 0.0218 |
Brugia malayi | Tyrosyl-DNA phosphodiesterase family protein | 0.0133 | 0.278 | 0.2771 |
Mycobacterium leprae | Polyketide synthase Pks13 | 0.0038 | 0.0621 | 1 |
Brugia malayi | Iron-sulfur cluster assembly accessory protein | 0.0049 | 0.0873 | 0.0861 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsE | 0.0017 | 0.0146 | 0.1162 |
Schistosoma mansoni | tar DNA-binding protein | 0.0128 | 0.2664 | 0.7535 |
Loa Loa (eye worm) | steroid hormone receptor | 0.002 | 0.0231 | 0.0218 |
Mycobacterium ulcerans | phenolpthiocerol synthesis type-I polyketide synthase PpsC | 0.0027 | 0.0375 | 0.5413 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.002 | 0.0231 | 0.0618 |
Trypanosoma brucei | tyrosyl-DNA Phosphodiesterase (Tdp1), putative | 0.0133 | 0.278 | 1 |
Mycobacterium tuberculosis | Probable cytochrome P450 125 Cyp125 | 0.0014 | 0.0084 | 0.1351 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.02 | 0.0187 |
Onchocerca volvulus | 0.0023 | 0.0302 | 0.1109 | |
Mycobacterium tuberculosis | Probable polyketide synthase Pks8 | 0.0021 | 0.0235 | 0.3792 |
Echinococcus granulosus | lamin | 0.0027 | 0.0387 | 0.0374 |
Brugia malayi | Cytochrome P450 family protein | 0.0022 | 0.0278 | 0.0266 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0231 | 0.0218 |
Mycobacterium tuberculosis | Polyketide synthase Pks13 | 0.0038 | 0.0621 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.