Species | Target name | Source | Bibliographic reference |
---|---|---|---|
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | epsilon tubulin, putative | Curated by TDR Targets | References |
Homo sapiens | nuclear factor, erythroid 2-like 2 | Starlite/ChEMBL | No references |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Plasmodium falciparum | tubulin beta chain | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Homo sapiens | thyroid hormone receptor, beta | Starlite/ChEMBL | No references |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Homo sapiens | vitamin D (1,25- dihydroxyvitamin D3) receptor | Starlite/ChEMBL | No references |
Leishmania major | gamma-tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | zeta tubulin, putative | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | delta tubulin, putative | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | beta tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Leishmania major | alpha tubulin | Curated by TDR Targets | References |
Species | Potential target | Known druggable target | Length | Alignment span | Identity |
---|---|---|---|---|---|
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Trypanosoma brucei | epsilon tubulin | epsilon tubulin, putative | 470 aa | 488 aa | 68.0 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin epsilon chain, putative | gamma-tubulin | 447 aa | 479 aa | 28.2 % |
Brugia malayi | steroid hormone receptor | vitamin D (1,25- dihydroxyvitamin D3) receptor | 427 aa | 416 aa | 24.5 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | tubulin beta chain | 445 aa | 438 aa | 33.6 % |
Brugia malayi | photoreceptor-specific nuclear receptor | thyroid hormone receptor, beta | 461 aa | 414 aa | 24.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | alpha tubulin | 451 aa | 457 aa | 30.9 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Plasmodium falciparum | tubulin gamma chain | beta tubulin | 443 aa | 438 aa | 33.6 % |
Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Leishmania major | gamma-tubulin | 0.040706 | 0.329353 | 0.00286857 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0654453 | 1 | 1 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0482416 | 0.533634 | 0.409701 |
Echinococcus granulosus | beta tubulin | 0.0654453 | 1 | 1 |
Echinococcus granulosus | tubulin beta 1 chain | 0.0654453 | 1 | 1 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0610338 | 0.880413 | 0.822195 |
Trypanosoma brucei | beta tubulin | 0.0654453 | 1 | 1 |
Brugia malayi | Tubulin beta-1 chain | 0.0654453 | 1 | 1 |
Echinococcus granulosus | tubulin alpha chain | 0.0482416 | 0.533634 | 0.409701 |
Trypanosoma brucei | epsilon tubulin | 0.0406348 | 0.327424 | 0.148692 |
Echinococcus granulosus | beta tubulin | 0.0654453 | 1 | 1 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0406348 | 0.327424 | 0.327424 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.0482416 | 0.533634 | 0.409701 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Trypanosoma brucei | beta tubulin | 0.0654453 | 1 | 1 |
Trypanosoma cruzi | tubulin delta chain | 0.0432904 | 0.399413 | 0.107035 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0482416 | 0.533634 | 0.409701 |
Echinococcus granulosus | tubulin subunit beta | 0.0654453 | 1 | 1 |
Echinococcus granulosus | tubulin alpha chain | 0.0482416 | 0.533634 | 0.409701 |
Leishmania major | delta tubulin, putative | 0.0432904 | 0.399413 | 0.107035 |
Echinococcus multilocularis | tubulin alpha chain | 0.0482416 | 0.533634 | 0.409701 |
Trypanosoma brucei | zeta tubulin | 0.0610338 | 0.880413 | 0.848634 |
Leishmania major | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Echinococcus multilocularis | tubulin subunit beta | 0.0654453 | 1 | 1 |
Echinococcus granulosus | peroxisome assembly protein 26 | 0.0482416 | 0.533634 | 0.409701 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0654453 | 1 | 1 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Echinococcus granulosus | tubulin alpha chain | 0.0482416 | 0.533634 | 0.409701 |
Toxoplasma gondii | beta-tubulin, putative | 0.0654453 | 1 | 1 |
Echinococcus granulosus | tubulin beta 4A class IVa | 0.0654453 | 1 | 1 |
Trypanosoma cruzi | alpha tubulin, putative | 0.0482416 | 0.533634 | 0.306598 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0654453 | 1 | 1 |
Echinococcus granulosus | tubulin alpha chain | 0.0482416 | 0.533634 | 0.409701 |
Loa Loa (eye worm) | tubulin beta-2A chain | 0.0654453 | 1 | 1 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0482416 | 0.533634 | 0.533634 |
Giardia lamblia | Beta tubulin | 0.0654453 | 1 | 1 |
Schistosoma mansoni | tubulin subunit beta | 0.0654453 | 1 | 1 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0654453 | 1 | 1 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0482416 | 0.533634 | 0.533634 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.0482416 | 0.533634 | 0.409701 |
Loa Loa (eye worm) | beta-tubulin | 0.0654453 | 1 | 1 |
Plasmodium falciparum | alpha tubulin 2 | 0.0482416 | 0.533634 | 0.306598 |
Plasmodium falciparum | tubulin beta chain | 0.0654453 | 1 | 1 |
Loa Loa (eye worm) | BEN-1 protein | 0.0654453 | 1 | 1 |
Brugia malayi | Tubulin alpha-2 chain | 0.0482416 | 0.533634 | 0.304603 |
Leishmania major | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Loa Loa (eye worm) | BEN-1 protein | 0.0654453 | 1 | 1 |
Brugia malayi | tubulin alpha chain - mouse | 0.0482416 | 0.533634 | 0.304603 |
Loa Loa (eye worm) | tubulin beta-4 chain | 0.0654453 | 1 | 1 |
Brugia malayi | alpha-tubulin | 0.0482416 | 0.533634 | 0.304603 |
Trichomonas vaginalis | tubulin, putative | 0.0654453 | 1 | 1 |
Schistosoma mansoni | tubulin subunit beta | 0.0654453 | 1 | 1 |
Trypanosoma brucei | beta tubulin | 0.0654453 | 1 | 1 |
Echinococcus multilocularis | peroxisome assembly protein 26 | 0.0482416 | 0.533634 | 0.409701 |
Leishmania major | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Echinococcus granulosus | tubulin alpha 3 chain | 0.0482416 | 0.533634 | 0.409701 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0482416 | 0.533634 | 0.533634 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0316253 | 0.0831889 | 0.0831889 |
Echinococcus granulosus | Tubulin alpha 1 chain | 0.0482416 | 0.533634 | 0.409701 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0482416 | 0.533634 | 0.533634 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Trypanosoma cruzi | tubulin delta chain | 0.0432904 | 0.399413 | 0.107035 |
Leishmania major | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0654453 | 1 | 1 |
Schistosoma mansoni | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Giardia lamblia | Beta tubulin | 0.0654453 | 1 | 1 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0654453 | 1 | 1 |
Toxoplasma gondii | beta tubulin | 0.0654453 | 1 | 1 |
Echinococcus multilocularis | tubulin beta 1 chain | 0.0654453 | 1 | 1 |
Plasmodium vivax | tubulin beta chain, putative | 0.0654453 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0482416 | 0.533634 | 0.533634 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.0482416 | 0.533634 | 0.409701 |
Trypanosoma brucei | alpha tubulin | 0.0482416 | 0.533634 | 0.409701 |
Brugia malayi | Tubulin alpha chain | 0.0482416 | 0.533634 | 0.304603 |
Echinococcus multilocularis | tubulin epsilon chain | 0.0406348 | 0.327424 | 0.148692 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0482416 | 0.533634 | 0.533634 |
Brugia malayi | beta-tubulin, identical | 0.0654453 | 1 | 1 |
Trypanosoma cruzi | zeta tubulin, putative | 0.0610338 | 0.880413 | 0.822195 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0654453 | 1 | 1 |
Echinococcus multilocularis | tubulin alpha 1C chain | 0.0482416 | 0.533634 | 0.409701 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Trypanosoma brucei | epsilon tubulin | 0.0406348 | 0.327424 | 0.148692 |
Echinococcus granulosus | alpha tubulin | 0.0482416 | 0.533634 | 0.409701 |
Loa Loa (eye worm) | tubulin beta chain | 0.0654453 | 1 | 1 |
Echinococcus multilocularis | tubulin alpha chain | 0.0482416 | 0.533634 | 0.409701 |
Schistosoma mansoni | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.040706 | 0.329353 | 0.329353 |
Plasmodium vivax | tubulin alpha chain, putative | 0.0482416 | 0.533634 | 0.306598 |
Trypanosoma cruzi | beta tubulin, putative | 0.0654453 | 1 | 1 |
Leishmania major | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Leishmania major | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Schistosoma mansoni | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Leishmania major | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Giardia lamblia | Alpha-tubulin | 0.0482416 | 0.533634 | 0.304603 |
Trypanosoma brucei | alpha tubulin | 0.0482416 | 0.533634 | 0.409701 |
Schistosoma mansoni | tubulin subunit beta | 0.0654453 | 1 | 1 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Trypanosoma brucei | beta tubulin | 0.0654453 | 1 | 1 |
Brugia malayi | tubulin alpha-2 chain | 0.0482416 | 0.533634 | 0.304603 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0654453 | 1 | 1 |
Echinococcus multilocularis | hypothetical protein | 0.0482416 | 0.533634 | 0.409701 |
Schistosoma mansoni | tubulin subunit alpha | 0.0482416 | 0.533634 | 0.306598 |
Brugia malayi | Tubulin alpha-2 chain | 0.0482416 | 0.533634 | 0.304603 |
Schistosoma mansoni | tubulin subunit beta | 0.0654453 | 1 | 1 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.0482416 | 0.533634 | 0.409701 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0654453 | 1 | 1 |
Toxoplasma gondii | tubulin/FtsZ family, GTPase domain-containing protein | 0.0432904 | 0.399413 | 0.239812 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0654453 | 1 | 1 |
Schistosoma mansoni | tubulin subunit alpha | 0.0482416 | 0.533634 | 0.306598 |
Leishmania major | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Giardia lamblia | Beta tubulin | 0.0654453 | 1 | 1 |
Trypanosoma brucei | tubulin gamma chain | 0.040706 | 0.329353 | 0.151134 |
Echinococcus granulosus | tubulin epsilon chain | 0.0406348 | 0.327424 | 0.148692 |
Schistosoma mansoni | tubulin subunit gamma | 0.040706 | 0.329353 | 0.00286857 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Echinococcus multilocularis | beta tubulin | 0.0654453 | 1 | 1 |
Toxoplasma gondii | alpha-tubulin I, putative | 0.0482416 | 0.533634 | 0.409701 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0482416 | 0.533634 | 0.533634 |
Echinococcus multilocularis | tubulin alpha chain | 0.0482416 | 0.533634 | 0.409701 |
Toxoplasma gondii | beta-1 tubulin, putative | 0.0654453 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0316253 | 0.0831889 | 0.0831889 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Entamoeba histolytica | tubulin alpha-1 chain | 0.0482416 | 0.533634 | 0.304603 |
Trichomonas vaginalis | tubulin alpha chain, putative | 0.0363013 | 0.209949 | 0.209949 |
Echinococcus multilocularis | tubulin alpha chain | 0.0482416 | 0.533634 | 0.409701 |
Echinococcus multilocularis | tubulin subunit TubB | 0.0482416 | 0.533634 | 0.409701 |
Loa Loa (eye worm) | tubulin alpha-2 chain | 0.0482416 | 0.533634 | 0.533634 |
Entamoeba histolytica | tubulin family protein | 0.0654453 | 1 | 1 |
Trichomonas vaginalis | tubulin gamma chain, putative | 0.0654453 | 1 | 1 |
Trypanosoma brucei | zeta tubulin, putative | 0.0610338 | 0.880413 | 0.848634 |
Echinococcus granulosus | tubulin gamma 1 chain | 0.040706 | 0.329353 | 0.151134 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0654453 | 1 | 1 |
Trypanosoma brucei | alpha tubulin | 0.0482416 | 0.533634 | 0.409701 |
Leishmania major | zeta tubulin, putative | 0.0610338 | 0.880413 | 0.822195 |
Echinococcus multilocularis | beta tubulin | 0.0654453 | 1 | 1 |
Trichomonas vaginalis | tubulin epsilon chain, putative | 0.0482416 | 0.533634 | 0.533634 |
Loa Loa (eye worm) | alpha-tubulin isotype 2 | 0.0316253 | 0.0831889 | 0.0831889 |
Echinococcus multilocularis | Tubulin beta 2C chain | 0.0654453 | 1 | 1 |
Leishmania major | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Schistosoma mansoni | tubulin subunit beta | 0.0654453 | 1 | 1 |
Schistosoma mansoni | tubulin subunit alpha | 0.0482416 | 0.533634 | 0.306598 |
Trypanosoma brucei | alpha tubulin | 0.0482416 | 0.533634 | 0.409701 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Entamoeba histolytica | tubulin family protein | 0.0654453 | 1 | 1 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Loa Loa (eye worm) | tubulin beta-1 chain | 0.0654453 | 1 | 1 |
Loa Loa (eye worm) | tubulin gamma chain | 0.040706 | 0.329353 | 0.329353 |
Echinococcus granulosus | tubulin subunit TubB | 0.0482416 | 0.533634 | 0.409701 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Loa Loa (eye worm) | alpha-tubulin | 0.0482416 | 0.533634 | 0.533634 |
Loa Loa (eye worm) | tubulin alpha chain | 0.0482416 | 0.533634 | 0.533634 |
Trypanosoma cruzi | tubulin gamma chain | 0.040706 | 0.329353 | 0.00286857 |
Loa Loa (eye worm) | alpha-tubulin | 0.0482416 | 0.533634 | 0.533634 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0482416 | 0.533634 | 0.409701 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0482416 | 0.533634 | 0.533634 |
Echinococcus multilocularis | tubulin alpha chain | 0.0482416 | 0.533634 | 0.409701 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0482416 | 0.533634 | 0.409701 |
Echinococcus multilocularis | Tubulin alpha 1 chain | 0.0482416 | 0.533634 | 0.409701 |
Echinococcus granulosus | tubulin alpha 1C chain | 0.0482416 | 0.533634 | 0.409701 |
Plasmodium vivax | tubulin alpha chain, putative | 0.0482416 | 0.533634 | 0.306598 |
Toxoplasma gondii | alpha tubulin TUBA1 | 0.0482416 | 0.533634 | 0.409701 |
Plasmodium falciparum | alpha tubulin 1 | 0.0482416 | 0.533634 | 0.306598 |
Trypanosoma brucei | tubulin delta chain | 0.0432904 | 0.399413 | 0.239812 |
Schistosoma mansoni | tubulin subunit beta | 0.0654453 | 1 | 1 |
Echinococcus multilocularis | tubulin, beta 4A class IVa | 0.0654453 | 1 | 1 |
Plasmodium vivax | tubulin gamma chain, putative | 0.040706 | 0.329353 | 0.00286857 |
Trichomonas vaginalis | tubulin alpha-1 chain, putative | 0.0316253 | 0.0831889 | 0.0831889 |
Echinococcus granulosus | tubulin alpha chain | 0.0482416 | 0.533634 | 0.409701 |
Plasmodium falciparum | tubulin gamma chain | 0.040706 | 0.329353 | 0.00286857 |
Loa Loa (eye worm) | tubulin alpha 2 | 0.0316253 | 0.0831889 | 0.0831889 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0654453 | 1 | 1 |
Echinococcus multilocularis | tubulin alpha 3 chain | 0.0482416 | 0.533634 | 0.409701 |
Giardia lamblia | Alpha-tubulin | 0.0482416 | 0.533634 | 0.304603 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Leishmania major | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Leishmania major | beta tubulin | 0.0654453 | 1 | 1 |
Echinococcus granulosus | Tubulin beta 2C chain | 0.0654453 | 1 | 1 |
Loa Loa (eye worm) | tubulin alpha chain | 0.0482416 | 0.533634 | 0.533634 |
Entamoeba histolytica | tubulin alpha chain, putative | 0.0482416 | 0.533634 | 0.304603 |
Leishmania major | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Leishmania major | alpha tubulin | 0.0482416 | 0.533634 | 0.306598 |
Trichomonas vaginalis | tubulin beta chain, putative | 0.0482416 | 0.533634 | 0.533634 |
Echinococcus multilocularis | tubulin gamma 1 chain | 0.040706 | 0.329353 | 0.151134 |
Activity type | Activity value | Assay description | Source | Reference |
---|---|---|---|---|
GI50 (functional) | -4.794 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the NCI-H23 Non-Small Cell Lung cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.76 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SN12C Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.746 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the ACHN Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.731 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the UO-31 Renal cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.715 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SK-MEL-5 Melanoma cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
GI50 (functional) | -4.706 | PUBCHEM_BIOASSAY: NCI human tumor cell line growth inhibition assay. Data for the SF-539 Central Nervous System cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
IC50 (functional) | = 4.187 | Antileishmanial activity against Leishmania donovani | ChEMBL. | 20728249 |
IC50 (functional) | = 800 nM | Antimicrobial activity against Cryptosporidium parvum infected in HCT8 cells assessed as parasite count after 72 to 120 hrs | ChEMBL. | 21889338 |
IC50 (functional) | = 0.25 uM | Antimicrobial activity against Toxoplasma gondii infected in HFF after 8 days by plaque assay | ChEMBL. | 20675138 |
IC50 (functional) | = 0.25 uM | Antimicrobial activity against Toxoplasma gondii RH infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 0.7 uM | Antimicrobial activity against Cryptosporidium parvum by short-term in vitro culture assay | ChEMBL. | 20145086 |
IC50 (functional) | = 1.26 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin F24H mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 1.4 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin H28Q mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 1.5 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin S6I mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 1.6 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235L mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 2.2 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243C mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 2.3 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235V mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 5.5 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin I235T mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 12 uM | Inhibitory concentration against brucei variant 221 was determined in vitro | ChEMBL. | 15027874 |
IC50 (functional) | = 12 uM | Inhibitory concentration against brucei variant 221 was determined in vitro | ChEMBL. | 15027874 |
IC50 (functional) | = 14.7 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin V4L mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 16 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin R243S mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 25.3 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin T239I mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 27.7 uM | Antimicrobial activity against Toxoplasma gondii RH containing alpha1-tubulin L136F mutation infected in HFF cells by plaque assay | ChEMBL. | 20145086 |
IC50 (functional) | = 44 uM | In vitro cytotoxicity against mouse J774 macrophages. | ChEMBL. | 15027874 |
IC50 (functional) | = 44 uM | In vitro cytotoxicity against mouse J774 macrophages. | ChEMBL. | 15027874 |
IC50 (functional) | = 44.1 uM | Inhibitory activity against Leishmania donovani promastigotes | ChEMBL. | 12161141 |
IC50 (functional) | = 44.1 uM | Inhibitory activity against Leishmania donovani promastigotes | ChEMBL. | 12161141 |
IC50 (functional) | = 56 uM | In vitro cytotoxicity against mouse PC3 prostate cancer cell line. | ChEMBL. | 15027874 |
IC50 (functional) | = 56 uM | In vitro cytotoxicity against mouse PC3 prostate cancer cell line. | ChEMBL. | 15027874 |
IC50 (functional) | = 65 uM | Inhibitory concentration against Leishmania donovani axenic amastigotes was determined in vitro | ChEMBL. | 15027874 |
IC50 (functional) | = 65 uM | Inhibitory concentration against Leishmania donovani axenic amastigotes was determined in vitro | ChEMBL. | 15027874 |
IC50 (functional) | = 72.5 uM | Inhibitory activity against Leishmania donovani amastigotes | ChEMBL. | 12161141 |
IC50 (functional) | = 72.5 uM | Inhibitory activity against Leishmania donovani amastigotes | ChEMBL. | 12161141 |
Inhibition (functional) | = 54 % | Percentage inhibition against Leishmania tubulin in vitro was determined at 20 uM | ChEMBL. | 12161141 |
LD50 (ADMET) | = 1600 mg kg-1 | Toxicity in po dosed mouse | ChEMBL. | 20728249 |
Potency (functional) | 0.0178 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of thyroid hormone receptor beta signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 19.3257 uM | PubChem BioAssay: Tox21. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 19.9526 uM | PUBCHEM_BIOASSAY: Inhibitors of the vitamin D receptor (VDR): qHTS. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504855] | ChEMBL. | No reference |
Potency (functional) | 22.3872 uM | PubChem BioAssay. qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 24.5412 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the AP-1 signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 26.1775 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (binding) | = 28.1838 um | PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Tyrosyl-DNA Phosphodiesterase (TDP1). (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 29.3717 uM | PubChem BioAssay: Tox21. qHTS assay for small molecule activators of the heat shock response signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | = 35.4813 um | PUBCHEM_BIOASSAY: VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 41.4886 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 44.6684 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule antagonists of glucocorticoid receptor signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 50.1187 uM | PUBCHEM_BIOASSAY: qHTS assay for small molecule agonists of peroxisome proliferator-activated receptor gamma signaling. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 50.1187 uM | PubChem BioAssay. A Novel Cell-Based Assay to Identify Small Molecules for B -Galactocerebrosidase. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 51.7849 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 52.231 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the NFkB signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 58.6042 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule antagonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 61.1306 uM | PubChem BioAssay. qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Potency (functional) | 65.7549 uM | PubChem BioAssay: Tox21. qHTS assay to identify small molecule agonists of the peroxisome proliferator-activated receptor delta (PPARd) signaling pathway. (Class of assay: confirmatory) | ChEMBL. | No reference |
Species name | Source | Reference | Is orphan |
---|---|---|---|
Trypanosoma brucei | ChEMBL23 | 15027874 | |
Cryptosporidium parvum | ChEMBL23 | 20145086 | |
Toxoplasma gondii | 20145086 | ||
Trypanosoma brucei gambiense | 15027874 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.
Affected Entity | Phenotypic quality | Occurs in | Occurs at | Evidence | Observed in | Targets |
---|---|---|---|---|---|---|
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 26882 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 26953 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29919 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 25756 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29777 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 25113 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29099 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 28601 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 24472 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 21739 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 28044 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 21309 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 24440 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 20919 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 22594 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 23453 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 21545 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29554 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29031 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 23905 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 21179 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 25450 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 22205 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 27459 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 26961 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 22252 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 23996 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 23078 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 20827 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 28024 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 28324 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 26882 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 26953 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 29919 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 25756 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 29777 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 25113 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 29099 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 28601 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 24472 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 21739 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 28044 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 21309 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 24440 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 20919 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 22594 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 23453 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 21545 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 29554 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 29031 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 23905 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 21179 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 25450 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 22205 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 27459 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 26961 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 22252 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 23996 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 23078 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 20827 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 28024 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
morphology (PATO:0000051) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from visible phenotype (ECO:0000176) | Leishmania mexicana | 28324 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 26882 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 26953 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29919 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 25756 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29777 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 25113 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29099 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 28601 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 24472 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 21739 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 28044 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 21309 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 24440 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 20919 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 22594 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 23453 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 21545 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29554 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29031 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 23905 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 21179 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 25450 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 22205 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 27459 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 26961 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 22252 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 23996 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 23078 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 20827 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 28024 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 28324 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 26882 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 26953 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29919 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 25756 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29777 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 25113 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29099 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 28601 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 24472 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 21739 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 28044 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 21309 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 24440 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 20919 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 22594 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 23453 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 21545 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29554 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 29031 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 23905 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 21179 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 25450 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 22205 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 27459 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 26961 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 22252 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 23996 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 23078 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 20827 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 28024 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
cell differentiation (GO:0030154) | disrupted (PATO:0001507) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania mexicana | 28324 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to disrupted differentiation from promastigote to amastigote of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 2044859 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 26882 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 26953 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 29919 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 25756 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 29777 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 25113 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 29099 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 28601 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 24472 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 21739 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 28044 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 21309 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 24440 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 20919 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 22594 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 23453 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 21545 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 29554 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 29031 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 23905 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 21179 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 25450 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 22205 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 27459 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 26961 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 22252 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 23996 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 23078 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 20827 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 28024 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania amazonensis | 28324 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 29091-21-2. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 7818612 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 26882 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 26953 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 29919 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 25756 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 29777 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 25113 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 29099 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 28601 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 24472 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 21739 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 28044 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 21309 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 24440 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 20919 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 22594 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 23453 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 21545 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 29554 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 29031 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 23905 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 21179 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 25450 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 22205 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 27459 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 26961 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 22252 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 23996 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 23078 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 20827 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 28024 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | drug insensitive (PATO:0000528) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania infantum | 28324 |
Annotator: | aaronjr@u.washington.edu | Comment: | chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 10546848 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 26882 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 26953 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29919 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 25756 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29777 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 25113 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29099 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28601 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 24472 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21739 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28044 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21309 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 24440 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 20919 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 22594 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23453 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21545 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29554 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29031 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23905 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21179 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 25450 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 22205 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 27459 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 26961 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 22252 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23996 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23078 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 20827 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28024 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28324 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 26882 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 26953 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29919 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 25756 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29777 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 25113 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29099 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28601 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 24472 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21739 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28044 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21309 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 24440 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 20919 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 22594 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23453 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21545 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29554 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29031 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23905 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21179 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 25450 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 22205 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 27459 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 26961 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 22252 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23996 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23078 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 20827 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28024 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28324 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents leads to slow growth of Leishmania sp. in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 26882 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 26953 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 29919 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 25756 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 29777 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 25113 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 29099 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 28601 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 24472 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 21739 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 28044 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 21309 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 24440 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 20919 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 22594 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 23453 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 21545 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 29554 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 29031 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 23905 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 21179 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 25450 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 22205 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 27459 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 26961 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 22252 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 23996 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 23078 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 20827 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 28024 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 28324 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 10228-56-5; Drug: 36317-95-0; Drug: 62409-47-6; Drug: 62745-74-8; Drug: 204634-79-7; Drug: 483279-40-9; Drug: 483279-41-0; Drug: 483279-42-1; Drug: 483279-43-2; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 483279-46-5; Drug: 483279-47-6; Drug: 88-91-5; Drug: 107-10-8; Drug: 1930-72-9; Drug: 97-08-5; Drug: 97-09-6; Drug: 62443-96-3; Drug: 483279-33-0; Drug: 483279-34-1; Drug: 483279-35-2; Drug: 483279-36-3; Drug: 483279-37-4; Drug: 483279-38-5; Drug: 483279-39-6. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase II gene/enzyme was studied | References: | 12161141 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 26882 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 26953 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29919 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 25756 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29777 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 25113 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29099 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28601 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 24472 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21739 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28044 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21309 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 24440 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 20919 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 22594 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23453 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21545 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29554 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29031 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23905 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21179 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 25450 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 22205 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 27459 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 26961 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 22252 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23996 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23078 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 20827 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28024 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
cell cycle arrest (GO:0007050) | abnormal (PATO:0000460) | single cell organism (CARO:0000064) | promastigote (BTO:0001124) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28324 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-40-9; Drug: 483279-44-3. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase II gene/enzyme was studied | References: | 14645662 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 26882 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 26953 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29919 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 25756 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29777 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 25113 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29099 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28601 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 24472 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21739 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28044 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21309 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 24440 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 20919 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 22594 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23453 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21545 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29554 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 29031 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23905 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 21179 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 25450 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 22205 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 27459 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 26961 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 22252 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23996 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 23078 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 20827 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28024 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
growth (GO:0040007) | decreased time (PATO:0000716) | single cell organism (CARO:0000064) | amastigote (BTO:0000062) | inferred from bioassay (ECO:0000094) | Leishmania donovani | 28324 |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents leads to cell cycle arrest in cell assay; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 26882 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 26953 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 29919 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 25756 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 29777 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 25113 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 29099 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 28601 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 24472 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 21739 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 28044 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 21309 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 24440 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 20919 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 22594 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 23453 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 21545 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 29554 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 29031 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 23905 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 21179 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 25450 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 22205 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 27459 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 26961 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 22252 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 23996 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 23078 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 20827 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 28024 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania donovani | 28324 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 19044-89-4; Drug: 19044-94-1; Drug: 483279-44-3; Drug: 483279-45-4; Drug: 619267-13-9; Drug: 619267-14-0; Drug: 619267-15-1; Drug: 619267-16-2; Drug: 619267-17-3; Drug: 619267-18-4; Drug: 619267-19-5; Drug: 619267-20-8; Drug: 619267-21-9; Drug: 619267-22-0; Drug: 619267-23-1; Drug: 619267-24-2; Drug: 619267-25-3; Drug: 619267-26-4; Drug: 678187-02-5; Drug: 678187-03-6; Drug: 678187-04-7; Drug: 678187-05-8; Drug: 678187-06-9; Drug: 678187-07-0; Drug: 678187-08-1; Drug: 678187-09-2; Drug: 678187-10-5; Drug: 678187-11-6; Drug: 678187-12-7; Drug: 678187-13-8; Drug: 678187-14-9. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 15027874 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 26882 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 26953 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 29919 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 25756 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 29777 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 25113 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 29099 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 28601 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 24472 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 21739 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 28044 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 21309 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 24440 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 20919 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 22594 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 23453 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 21545 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 29554 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 29031 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 23905 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 21179 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 25450 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 22205 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 27459 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 26961 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 22252 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 23996 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 23078 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 20827 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 28024 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
microtubule polymerization (GO:0046785) | decreased (PATO:0000468) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Leishmania tarentolae | 28324 | |
Annotator: | aaronjr@u.washington.edu | Comment: | Drug: 483279-44-3; Drug: 619267-15-1. chemical inhibition with antimicrotubule agents prevents mictotubule formation in vitro with purified tubulin; unclear as to which topoisomerase I gene(s)/enzyme(s) was/were studied | References: | 16753146 | |
catalytic activity (GO:0003824) | normal (PATO:0000461) | in vitro (MI:0492) | inferred from specific protein inhibition (ECO:0000020) | Plasmodium falciparum | 1160 | |
Annotator: | saralph@unimelb.edu.au | Comment: | 012/Mar/09 | References: | 16406111 | |
growth (GO:0040007) | lethal (sensu genetics) (PATO:0000718) | multi-cellular organism (CARO:0000012) | bloodstream stage (PLO:0040) | in vivo inhibition (TDR:00016) | Plasmodium falciparum | 1160 |
Annotator: | saralph@unimelb.edu.au | Comment: | 012/Mar/09 | References: | 12654761 16406111 |
20 literature references were collected for this gene.