Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0047 | 0.4931 | 0.4243 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.1195 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1195 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0166 | 0.0123 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.4931 | 0.6664 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.1195 | 0.5 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.1195 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0024 | 0.1195 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.3712 | 0.3972 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0166 | 0.0123 |
Schistosoma mansoni | hypothetical protein | 0.0021 | 0.0667 | 0.0774 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.4931 | 0.6148 |
Schistosoma mansoni | zinc finger protein | 0.002 | 0.0486 | 0.0546 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0166 | 0.0123 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0037 | 0.3293 | 0.4427 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0024 | 0.1195 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.1195 | 1 |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0018 | 0.0166 | 0.139 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1195 | 0.124 |
Mycobacterium ulcerans | hypothetical protein | 0.0024 | 0.1195 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0044 | 0.4446 | 0.4769 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0024 | 0.1195 | 1 |
Schistosoma mansoni | bromodomain containing protein | 0.0065 | 0.7988 | 1 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0024 | 0.1195 | 1 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0024 | 0.1195 | 1 |
Echinococcus granulosus | zinc finger protein | 0.002 | 0.0486 | 0.0592 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0018 | 0.0166 | 0.5 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.1195 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.1195 | 0.124 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0166 | 0.0123 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0047 | 0.4931 | 0.5296 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.1195 | 0.5 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0024 | 0.1195 | 0.5 |
Onchocerca volvulus | 0.0024 | 0.1195 | 0.5 | |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0061 | 0.7374 | 1 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0018 | 0.0158 | 0.0114 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0024 | 0.1195 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.4931 | 0.6148 |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0018 | 0.0166 | 0.5 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0061 | 0.7374 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0037 | 0.3293 | 0.4427 |
Loa Loa (eye worm) | hypothetical protein | 0.0073 | 0.9266 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.4931 | 0.6664 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0024 | 0.1195 | 1 |
Echinococcus multilocularis | zinc finger protein | 0.002 | 0.0486 | 0.0592 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0023 | 0.0995 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0166 | 0.0123 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0047 | 0.4931 | 0.6148 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0023 | 0.0995 | 0.1287 |
Brugia malayi | Bromodomain containing protein | 0.0039 | 0.37 | 0.2845 |
Brugia malayi | PHD-finger family protein | 0.0026 | 0.1401 | 0.0234 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0024 | 0.1195 | 0.5 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0024 | 0.1195 | 0.5 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0023 | 0.0995 | 0.1188 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0047 | 0.4931 | 0.6664 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.4118 | 0.4413 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0047 | 0.4931 | 0.6664 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0024 | 0.1195 | 0.5 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0018 | 0.0166 | 0.5 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0021 | 0.0667 | 0.0667 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.