Detailed information for compound 793169

Basic information

Technical information
  • TDR Targets ID: 793169
  • Name: 3,4,5-trimethoxy-N-[[1-(2-methylprop-2-enyl)b enzimidazol-2-yl]methyl]benzamide
  • MW: 395.452 | Formula: C22H25N3O4
  • H donors: 1 H acceptors: 2 LogP: 3.53 Rotable bonds: 9
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1cc(cc(c1OC)OC)C(=O)NCc1nc2c(n1CC(=C)C)cccc2
  • InChi: 1S/C22H25N3O4/c1-14(2)13-25-17-9-7-6-8-16(17)24-20(25)12-23-22(26)15-10-18(27-3)21(29-5)19(11-15)28-4/h6-11H,1,12-13H2,2-5H3,(H,23,26)
  • InChiKey: GDUGBTFIQINBGF-UHFFFAOYSA-N  

Network

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Synonyms

  • 3,4,5-trimethoxy-N-[[1-(2-methylprop-2-enyl)-2-benzimidazolyl]methyl]benzamide
  • ST5116386

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Mycobacterium tuberculosis Probable oxidoreductase 0.0065 0.0333 0.0547
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0012 0.0005 0.0005
Plasmodium vivax 3-oxoacyl-[acyl-carrier-protein] reductase, putative 0.0065 0.0333 0.0568
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0013 0.0013 0.0022
Brugia malayi G-protein alpha subunit 0.0012 0.0005 0.0028
Mycobacterium ulcerans short chain dehydrogenase 0.0065 0.0333 0.0547
Trichomonas vaginalis set domain proteins, putative 0.0264 0.1564 0.2667
Loa Loa (eye worm) inositol-1 0.0036 0.0154 0.041
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0012 0.0005 0.001
Leishmania major hypothetical protein, conserved 0.0025 0.0087 0.2315
Loa Loa (eye worm) GTP-binding regulatory protein alpha chain 0.0012 0.0005 0.0012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0039 0.0066
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0049 0.0234 0.0234
Echinococcus multilocularis geminin 0.0336 0.2012 0.2012
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0195 0.5687
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0174 0.0174
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0156 0.0266
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0156 0.0333
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0289 0.8639
Toxoplasma gondii ABC1 family protein 0.0036 0.0156 0.0266
Mycobacterium tuberculosis Possible oxidoreductase 0.0065 0.0333 0.0547
Mycobacterium ulcerans short chain dehydrogenase 0.0065 0.0333 0.0547
Echinococcus multilocularis inositol monophosphatase 1 0.0036 0.0154 0.0154
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0012 0.0005 0.001
Trichomonas vaginalis GTP-binding protein (z) alpha subunit, gnaz, putative 0.0012 0.0005 0.0008
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0065 0.0333 0.0547
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0005 0.001
Onchocerca volvulus 0.0039 0.0174 0.1111
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0154 0.4409
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0959 0.5861 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0049 0.0234 0.05
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0065 0.0333 0.0887
Brugia malayi hypothetical protein 0.0039 0.0174 0.106
Mycobacterium tuberculosis Conserved protein 0.0036 0.0156 0.0245
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0174 0.0174
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0114 0.0195
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0039 0.0066
Schistosoma mansoni hypothetical protein 0.0336 0.2012 0.4303
Mycobacterium tuberculosis Conserved protein 0.0036 0.0156 0.0245
Schistosoma mansoni rab6-interacting 0.0039 0.0174 0.0371
Loa Loa (eye worm) hypothetical protein 0.0011 0.0001 0.0002
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0036 0.0154 0.0241
Loa Loa (eye worm) glutathione reductase 0.0038 0.0166 0.0443
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0043 0.0195 0.0332
Plasmodium vivax importin-beta 2, putative 0.0058 0.0289 0.0494
Onchocerca volvulus 0.0012 0.0005 0.0029
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0276 0.1638 0.3504
Brugia malayi Importin beta-1 subunit 0.0058 0.0289 0.1766
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0038 0.0166 0.0262
Onchocerca volvulus 0.0028 0.0103 0.0658
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0012
Brugia malayi GTP-binding regulatory protein alpha chain - starfish, putative 0.0012 0.0005 0.0028
Schistosoma mansoni 3-oxoacyl-[ACP] reductase 0.0065 0.0333 0.0712
Loa Loa (eye worm) hypothetical protein 0.0062 0.0317 0.0846
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0012
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0232 0.1366 0.3639
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0065 0.0333 1
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0174 0.0371
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0012 0.0005 0.001
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0012 0.0005 0.0005
Entamoeba histolytica G protein alpha subunit, putative 0.0012 0.0005 0.0139
Brugia malayi Inositol-1 0.0036 0.0154 0.0939
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0315 0.0839
Mycobacterium ulcerans short chain dehydrogenase 0.0065 0.0333 0.0547
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0011 0.0002 0.0003
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0096 0.0527 0.0879
Brugia malayi PHD-finger family protein 0.003 0.0114 0.0698
Loa Loa (eye worm) hypothetical protein 0.0036 0.0156 0.0415
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0087 0.0467 0.0777
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0098 0.0167
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0232 0.1366 0.2314
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0333 0.0547
Loa Loa (eye worm) fli-1 protein 0.0222 0.1303 0.3471
Loa Loa (eye worm) hypothetical protein 0.0039 0.0174 0.0463
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0013 0.0013 0.0027
Leishmania major oxidoreductase-like protein 0.0065 0.0333 1
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0043 0.0195 0.5687
Echinococcus granulosus chromobox protein 1 0.0068 0.0351 0.0751
Mycobacterium tuberculosis Conserved protein 0.0036 0.0156 0.0245
Onchocerca volvulus 0.0036 0.0156 0.0997
Brugia malayi Thioredoxin reductase 0.0038 0.0166 0.1014
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0167 0.0284
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0065 0.0333 0.0547
Schistosoma mansoni chromobox protein 0.0068 0.0351 0.0751
Loa Loa (eye worm) heterochromatin protein 1 0.0068 0.0351 0.0935
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0096 0.0527 0.0692
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0038 0.0167 0.1066
Brugia malayi beta-lactamase family protein 0.0036 0.0156 0.0951
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0276 0.1638 0.3504
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0156 0.4472
Entamoeba histolytica 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0065 0.0333 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0333 0.0547
Plasmodium falciparum importin beta, putative 0.0058 0.0289 0.0494
Schistosoma mansoni importin beta-1 0.0058 0.0289 0.0619
Trichomonas vaginalis esterase, putative 0.0036 0.0156 0.0266
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0315 0.0315
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0087 0.0148
Schistosoma mansoni mixed-lineage leukemia protein mll 0.006 0.0303 0.0648
Loa Loa (eye worm) hypothetical protein 0.0025 0.0087 0.0231
Schistosoma mansoni trimeric G-protein alpha o subunit 0.0012 0.0005 0.001
Leishmania major pteridine reductase 1 0.0065 0.0333 1
Loa Loa (eye worm) G protein alpha subunit 3 0.0012 0.0005 0.0012
Brugia malayi Bromodomain containing protein 0.003 0.0114 0.0698
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0315 0.0673
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0005 0.0008
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0087 0.0467 0.0587
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0309 0.0824
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-12 subunit 0.0012 0.0005 0.0012
Onchocerca volvulus 0.0065 0.0333 0.2129
Loa Loa (eye worm) RNA binding protein 0.0062 0.0315 0.0839
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0959 0.5861 1
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0005 0.0008
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0036 0.0154 0.4622
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0013 0.001 0.0021
Mycobacterium ulcerans short chain dehydrogenase 0.0065 0.0333 0.0547
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0276 0.1638 0.4365
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0043 0.0195 0.0332
Schistosoma mansoni GTP-binding protein alpha subunit gna 0.0012 0.0005 0.001
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0087 0.2315
Brugia malayi guanine nucleotide-binding protein G-o protein alpha subunit 0.0012 0.0005 0.0028
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0049 0.0234 0.0234
Brugia malayi Ets-domain containing protein 0.0073 0.0383 0.2338
Mycobacterium ulcerans oxidoreductase 0.0065 0.0333 0.0547
Schistosoma mansoni microtubule-associated protein tau 0.0767 0.4675 1
Schistosoma mansoni GTP-binding protein (I) alpha subunit gnai 0.0012 0.0005 0.001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0276 0.1638 0.3504
Loa Loa (eye worm) hypothetical protein 0.0036 0.0156 0.0415
Echinococcus multilocularis snurportin 1 0.0618 0.3753 0.3753
Mycobacterium ulcerans hypothetical protein 0.0036 0.0156 0.0245
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0087 0.0148
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0264 0.045
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0049 0.0234 0.05
Mycobacterium ulcerans short chain dehydrogenase 0.0065 0.0333 0.0547
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0959 0.5861 1
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0408 0.0872
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0043 0.0195 0.5687
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0049 0.0234 0.1426
Echinococcus granulosus muscleblind protein 0.015 0.0859 0.1837
Chlamydia trachomatis oxoacy-ACP reductase 0.0065 0.0333 0.0547
Loa Loa (eye worm) hypothetical protein 0.0065 0.0333 0.0887
Schistosoma mansoni dihydropteridine reductase 0.0065 0.0333 0.0712
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0156 0.0245
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0012 0.0005 0.001
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0013 0.0013 0.0027
Brugia malayi CHD4 protein 0.0013 0.001 0.006
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0154 0.4409
Plasmodium vivax glutathione reductase, putative 0.0038 0.0166 0.0284
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0065 0.0333 0.2032
Mycobacterium ulcerans short chain dehydrogenase 0.0065 0.0333 0.0547
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0012 0.0005 0.001
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0315 0.0839
Echinococcus multilocularis cpg binding protein 0.0029 0.0113 0.0113
Plasmodium falciparum 3-oxoacyl-[acyl-carrier-protein] reductase 0.0065 0.0333 0.0568
Echinococcus granulosus Chromobox protein 3 0.0011 0.0000000085961 0.000000018386
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.0073 0.0383 0.102
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0315 0.0673
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0163 0.0348
Brugia malayi guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0005 0.0028
Schistosoma mansoni cpg binding protein 0.0029 0.0113 0.0241
Schistosoma mansoni hypothetical protein 0.0039 0.0174 0.0371
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0096 0.0527 0.0879
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0156 0.0266
Brugia malayi RNA binding protein 0.0062 0.0315 0.1921
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0001 0.0002
Echinococcus granulosus guanine nucleotide binding protein G protein 0.0012 0.0005 0.001
Brugia malayi guanine nucleotide-binding protein alpha-7 subunit, putative 0.0012 0.0005 0.0028
Schistosoma mansoni loxhd1 0.0039 0.0174 0.0371
Schistosoma mansoni lipoxygenase 0.0171 0.099 0.2117
Mycobacterium ulcerans 20-beta-hydroxysteroid dehydrogenase FabG3 0.0065 0.0333 0.0547
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0114 0.0114
Toxoplasma gondii short chain dehydrogenase family protein, putative 0.0065 0.0333 0.0568
Brugia malayi beta-lactamase 0.0036 0.0156 0.0951
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0012
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0043 0.0195 1
Brugia malayi hypothetical protein 0.0016 0.0032 0.0193
Brugia malayi Fli-1 protein 0.0222 0.1303 0.7951
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0001 0.0001
Loa Loa (eye worm) CHromoDomain protein family member 0.0013 0.001 0.0026
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0333 0.0547
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0351 0.0599
Mycobacterium leprae POSSIBLE OXIDOREDUCTASE 0.0065 0.0333 0.0353
Onchocerca volvulus 0.0011 0.0000000085961 0.00000005498
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0156 0.0245
Brugia malayi hypothetical protein 0.0039 0.0174 0.106
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0013 0.0013 0.0077
Schistosoma mansoni hypothetical protein 0.0049 0.0234 0.05
Trichomonas vaginalis G protein (olf) alpha subunit, gnal, putative 0.0012 0.0005 0.0008
Echinococcus granulosus chromobox protein 1 0.0068 0.0351 0.0751
Trypanosoma cruzi trypanothione reductase, putative 0.0038 0.0166 0.4794
Plasmodium falciparum thioredoxin reductase 0.0038 0.0166 0.0284
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.0333 0.0547
Mycobacterium tuberculosis Probable oxidoreductase 0.0096 0.0527 0.0879
Loa Loa (eye worm) hypothetical protein 0.0154 0.0887 0.2362
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0114 0.0195
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0013 0.0013 0.0022
Trichomonas vaginalis conserved hypothetical protein 0.0014 0.0021 0.0036
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0959 0.5861 1
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0043 0.0195 0.0519
Loa Loa (eye worm) hypothetical protein 0.0036 0.0156 0.0415
Brugia malayi Heterochromatin protein 1 0.0068 0.0351 0.2143
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0114 0.0305
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0174 0.0296
Trichomonas vaginalis inositol monophosphatase, putative 0.0036 0.0154 0.0262
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0114 0.0245
Onchocerca volvulus 0.0264 0.1564 1
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0087 0.0148
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0065 0.0333 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0156 0.0415
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0039 0.0066
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0156 0.0266
Echinococcus multilocularis muscleblind protein 1 0.015 0.0859 0.0859
Echinococcus granulosus guanine nucleotide binding protein subunit 0.0012 0.0005 0.001
Toxoplasma gondii thioredoxin reductase 0.0038 0.0166 0.0284
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0005 0.0008
Echinococcus granulosus inositol monophosphatase 1 0.0036 0.0154 0.0329
Echinococcus granulosus tar DNA binding protein 0.0062 0.0315 0.0673
Loa Loa (eye worm) hypothetical protein 0.0034 0.014 0.0374
Echinococcus granulosus thioredoxin glutathione reductase 0.0038 0.0169 0.0362
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0276 0.1638 0.3504
Echinococcus granulosus GTP binding nuclear protein Ran 0.0043 0.0195 0.0417
Brugia malayi MH2 domain containing protein 0.0122 0.0686 0.4186
Brugia malayi Pre-SET motif family protein 0.0034 0.014 0.0856
Echinococcus multilocularis muscleblind protein 0.015 0.0859 0.0859
Trypanosoma brucei oxidoreductase-like protein 0.0065 0.0333 1
Onchocerca volvulus 0.0036 0.0156 0.0997
Plasmodium vivax thioredoxin reductase, putative 0.0038 0.0166 0.0284
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0005 0.001
Trichomonas vaginalis importin beta-1, putative 0.0047 0.0222 0.0378
Trichomonas vaginalis chromobox protein, putative 0.0068 0.0351 0.0599
Echinococcus multilocularis RUN 0.0039 0.0174 0.0174
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0156 0.0333
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0087 0.2315
Mycobacterium ulcerans 3-oxoacyl-ACP reductase 0.0065 0.0333 0.0547
Schistosoma mansoni GTP-binding protein (I) alpha-1subunit gnai1 0.0012 0.0005 0.001
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0098 0.0167
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0097 0.0531 0.1136
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0045 0.0209 0.0447
Brugia malayi SET domain containing protein 0.0013 0.0011 0.0069
Loa Loa (eye worm) hypothetical protein 0.0058 0.0289 0.0771
Plasmodium falciparum enoyl-acyl carrier reductase 0.0959 0.5861 1
Schistosoma mansoni gabp alpha 0.0073 0.0383 0.0819
Leishmania major trypanothione reductase 0.0038 0.0166 0.4794
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0005 0.0028
Schistosoma mansoni GTP-binding protein (q) alpha-11 subunit gna11 0.0012 0.0005 0.001
Loa Loa (eye worm) hypothetical protein 0.0106 0.0584 0.1557
Trichomonas vaginalis glutathione reductase, putative 0.0013 0.0013 0.0022
Loa Loa (eye worm) heterotrimeric G protein alpha subunit 0.0012 0.0005 0.0012
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0959 0.5861 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0276 0.1638 0.1638
Schistosoma mansoni cpg binding protein 0.0028 0.0103 0.022
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0156 0.0156
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0222 0.0378
Mycobacterium tuberculosis Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG2 (3-ketoacyl-acyl carrier protein reductase) 0.0065 0.0333 0.0547
Loa Loa (eye worm) hypothetical protein 0.015 0.0859 0.2288
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0156 0.4472
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0315 0.0673
Echinococcus multilocularis peregrin 0.003 0.0114 0.0114
Echinococcus multilocularis guanine nucleotide binding protein (G protein) 0.0012 0.0005 0.0005
Mycobacterium tuberculosis Possible 20-beta-hydroxysteroid dehydrogenase FabG3 (cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) 0.0065 0.0333 0.0547
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0114 0.0245
Loa Loa (eye worm) hypothetical protein 0.0039 0.0174 0.0463
Loa Loa (eye worm) oxidoreductase 0.0065 0.0333 0.0887
Echinococcus granulosus expressed protein 0.0012 0.0005 0.001
Schistosoma mansoni hypothetical protein 0.0618 0.3753 0.8028
Toxoplasma gondii HEAT repeat-containing protein 0.0058 0.0289 0.0494
Mycobacterium ulcerans short chain dehydrogenase 0.0065 0.0333 0.0547
Entamoeba histolytica hypothetical protein 0.0047 0.0222 0.6657
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0315 0.0673
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0087 0.2315
Echinococcus multilocularis gtp binding protein (I) alpha 1subunit 0.0012 0.0005 0.0005
Brugia malayi glutathione reductase 0.0038 0.0166 0.1014
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0039 0.0066
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.0333 0.0547
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0156 0.0245
Schistosoma mansoni ran 0.0043 0.0195 0.0417
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0171 0.099 0.099
Echinococcus granulosus importin subunit beta 1 0.0058 0.0289 0.0619
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0065 0.0333 0.0547
Echinococcus multilocularis thioredoxin glutathione reductase 0.0038 0.0169 0.0169
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0156 0.0245
Echinococcus multilocularis Chromobox protein 3 0.0011 0.0000000085961 0.0000000085961
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0012
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0186 0.0186
Brugia malayi Muscleblind-like protein 0.015 0.0859 0.5243
Loa Loa (eye worm) retinol dehydrogenase 12 0.0065 0.0333 0.0887
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0156 0.0245
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0014 0.0021 0.0036
Echinococcus multilocularis 3 oxoacyl acyl carrier protein reductase 0.0065 0.0333 0.0333
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0103 0.0274
Toxoplasma gondii 2,4-dienoyl CoA reductase 2, peroxisomal family protein 0.0065 0.0333 0.0568
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0156 0.4472
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0032 0.0131 0.0201
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0002 0.0003
Schistosoma mansoni inositol monophosphatase 0.0036 0.0154 0.0329
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0185 0.0315
Schistosoma mansoni ets-related 0.0222 0.1303 0.2786
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0154 0.4409
Echinococcus multilocularis chromobox protein 1 0.0068 0.0351 0.0351
Loa Loa (eye worm) hypothetical protein 0.0036 0.0156 0.0415
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0087 0.0467 0.0777
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0174 0.0371
Mycobacterium leprae 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) (MYCOLIC ACID BIOSYNTHESIS A PROTEI 0.0065 0.0333 0.0353
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0156 0.0266
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0156 0.0044
Brugia malayi guanine nucleotide-binding protein G(o), alpha subunit, putative 0.0012 0.0005 0.0028
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.014 0.03
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0156 0.0333
Leishmania major hypothetical protein, conserved 0.0036 0.0156 0.4472
Plasmodium falciparum phd finger protein, putative 0.003 0.0114 0.0195
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0186 0.0398
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.014 0.03
Echinococcus granulosus GPCR family 2 0.0049 0.0234 0.05
Mycobacterium ulcerans 3-alpha-hydroxysteroid dehydrogenase 0.0065 0.0333 0.0547
Trypanosoma cruzi oxidoreductase-like protein, putative 0.0065 0.0333 1
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0333 0.0547
Trichomonas vaginalis GTP-binding protein (O) alpha subunit, gnao, putative 0.0012 0.0005 0.0008
Schistosoma mansoni polycystin 1-related 0.0039 0.0174 0.0371
Schistosoma mansoni hypothetical protein 0.003 0.0114 0.0245
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0333 0.0547
Echinococcus granulosus gtp binding protein I alpha 1subunit 0.0012 0.0005 0.001
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0047 0.0222 0.0378
Brugia malayi jmjC domain containing protein 0.0097 0.0531 0.3241
Loa Loa (eye worm) hypothetical protein 0.0049 0.0234 0.0622
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0065 0.0333 0.0547
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0154 0.0887 0.5412
Echinococcus granulosus microtubule associated protein 2 0.0767 0.4675 1
Schistosoma mansoni hypothetical protein 0.0336 0.2012 0.4303
Trichomonas vaginalis hypothetical protein 0.0959 0.5861 1
Trypanosoma cruzi importin beta-1 subunit, putative 0.0047 0.0222 0.6524
Schistosoma mansoni inositol monophosphatase 0.0036 0.0154 0.0329
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0156 0.0951
Leishmania major GTP-binding protein, putative 0.0043 0.0195 0.5687
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0013 0.001 0.0021
Brugia malayi CXXC zinc finger family protein 0.0028 0.0103 0.0628
Trichomonas vaginalis conserved hypothetical protein 0.0038 0.0167 0.0284
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0097 0.0531 0.0531
Echinococcus multilocularis guanine nucleotide binding protein subunit 0.0012 0.0005 0.0005
Schistosoma mansoni GTP-binding protein (I) alpha-2 subunit gnai2 0.0012 0.0005 0.001
Mycobacterium ulcerans short chain dehydrogenase 0.0065 0.0333 0.0547
Onchocerca volvulus 0.0065 0.0333 0.2129
Brugia malayi F/Y-rich N-terminus family protein 0.0019 0.0051 0.0312
Brugia malayi RNA, U transporter 1 0.0165 0.0949 0.5795
Schistosoma mansoni jumonji/arid domain-containing protein 0.0037 0.0163 0.0348
Brugia malayi TAR-binding protein 0.0062 0.0315 0.1921
Brugia malayi jmjC domain containing protein 0.0037 0.0163 0.0993
Echinococcus granulosus snurportin 1 0.0618 0.3753 0.8028
Schistosoma mansoni hypothetical protein 0.0011 0.0001 0.0002
Plasmodium falciparum thioredoxin reductase 0.0013 0.0013 0.0022
Brugia malayi latrophilin 2 splice variant baaae 0.0106 0.0584 0.3567
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0032 0.0129 0.0276
Trypanosoma brucei beta-ketoacyl-ACP reductase 0.0065 0.0333 1
Brugia malayi beta-lactamase family protein 0.0036 0.0156 0.0951
Onchocerca volvulus 0.0039 0.0174 0.1111
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0333 0.0547
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0087 0.0467 0.0777
Trichomonas vaginalis mercuric reductase, putative 0.0013 0.0013 0.0022
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0276 0.1638 1
Schistosoma mansoni hypothetical protein 0.0049 0.0234 0.05
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0154 0.0262
Wolbachia endosymbiont of Brugia malayi Short-chain alcohol dehydrogenase family enzyme 0.0065 0.0333 0.0547
Brugia malayi Doublecortin family protein 0.0039 0.0174 0.106
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.014 0.014
Onchocerca volvulus 0.0036 0.0156 0.0997
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0065 0.0333 0.2032
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0156 0.0245
Schistosoma mansoni chromobox protein 0.0068 0.0351 0.0751
Echinococcus granulosus RUN 0.0039 0.0174 0.0371
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0017 0.0039 0.0066
Plasmodium vivax SET domain protein, putative 0.0034 0.014 0.0239
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.0686 0.1827
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0043 0.0195 0.0332
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0174 0.0296
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0036 0.0154 0.0262
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0315 0.0673
Onchocerca volvulus 0.0012 0.0005 0.0029
Trypanosoma brucei trypanothione reductase 0.0038 0.0166 0.4794
Loa Loa (eye worm) thioredoxin reductase 0.0038 0.0166 0.0443
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.014 0.014
Brugia malayi Latrophilin receptor protein 2 0.0049 0.0234 0.1426
Schistosoma mansoni hypothetical protein 0.0049 0.0234 0.05
Brugia malayi Pre-SET motif family protein 0.0232 0.1366 0.8336
Mycobacterium tuberculosis Probable dehydrogenase/reductase 0.0065 0.0333 0.0547
Plasmodium vivax hypothetical protein, conserved 0.003 0.0114 0.0195
Trypanosoma cruzi beta-ketoacyl-ACP reductase 0.0065 0.0333 1
Schistosoma mansoni ran 0.0043 0.0195 0.0417
Mycobacterium ulcerans short chain dehydrogenase 0.0065 0.0333 0.0547
Trichomonas vaginalis ran, putative 0.0043 0.0195 0.0332
Echinococcus granulosus 3 oxoacyl acyl carrier protein reductase 0.0065 0.0333 0.0712
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0156 0.0245
Leishmania major 3-oxoacyl-ACP reductase, putative 0.0065 0.0333 1
Toxoplasma gondii NADPH-glutathione reductase 0.0013 0.0013 0.0022
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0174 0.0463
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0013 0.0013 0.0022
Loa Loa (eye worm) jmjC domain-containing protein 0.0037 0.0163 0.0433
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.014 0.03
Echinococcus multilocularis chromobox protein 1 0.0068 0.0351 0.0351
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0013 0.0013 0.0013
Mycobacterium ulcerans short chain dehydrogenase 0.0065 0.0333 0.0547
Echinococcus multilocularis expressed protein 0.0012 0.0005 0.0005
Echinococcus granulosus GA binding protein alpha chain 0.0073 0.0383 0.0819
Loa Loa (eye worm) hypothetical protein 0.0036 0.0156 0.0415
Brugia malayi Guanine nucleotide-binding protein alpha-3 subunit, putative 0.0012 0.0005 0.0028
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.0686 0.1827
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0315 0.1921
Plasmodium falciparum glutathione reductase 0.0013 0.0013 0.0022
Schistosoma mansoni hypothetical protein 0.0106 0.0584 0.125
Brugia malayi Ets-domain containing protein 0.0073 0.0383 0.2338
Mycobacterium tuberculosis Possible oxidoreductase 0.0065 0.0333 0.0547
Onchocerca volvulus 0.003 0.0116 0.0741
Onchocerca volvulus Alhambra homolog 0.003 0.0114 0.0732
Mycobacterium tuberculosis Probable dehydrogenase 0.0087 0.0467 0.0777
Entamoeba histolytica Ran family GTPase 0.0043 0.0195 0.5851
Brugia malayi Calcitonin receptor-like protein seb-1 0.0154 0.0887 0.5412
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0174 0.0371
Schistosoma mansoni cpg binding protein 0.0029 0.0113 0.0241
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0041 0.0185 0.118
Brugia malayi chromobox protein homolog 3 0.0038 0.0167 0.1017
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0039 0.0066
Loa Loa (eye worm) hypothetical protein 0.0038 0.0167 0.0444
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0154 0.0887 0.2362
Echinococcus multilocularis microtubule associated protein 2 0.0767 0.4675 0.4675
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0959 0.5861 1
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0156 0.0266
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0065 0.0333 0.0547
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0156 0.0266
Mycobacterium ulcerans short chain dehydrogenase 0.0065 0.0333 0.0547
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0333 0.0547
Loa Loa (eye worm) latrophilin receptor protein 2 0.0049 0.0234 0.0622
Loa Loa (eye worm) hypothetical protein 0.0012 0.0005 0.0012
Onchocerca volvulus 0.0012 0.0005 0.0029
Mycobacterium ulcerans beta-lactamase 0.0036 0.0156 0.0245
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0013 0.001 0.001
Trichomonas vaginalis GTP-binding protein alpha subunit, gna, putative 0.0012 0.0005 0.0008
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0036 0.0154 0.0241
Trypanosoma brucei importin beta-1 subunit, putative 0.0058 0.0289 0.8639
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0036 0.0154 0.4409
Loa Loa (eye worm) hypothetical protein 0.0051 0.0245 0.0653
Echinococcus granulosus lysine specific demethylase 5A 0.0037 0.0163 0.0348
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0065 0.0333 0.0547
Echinococcus granulosus cpg binding protein 0.0029 0.0113 0.0241
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0153 0.0153
Trichomonas vaginalis chromobox protein, putative 0.0041 0.0185 0.0315
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.014 0.03
Brugia malayi PHD-finger family protein 0.0011 0.0001 0.0006
Brugia malayi hypothetical protein 0.0025 0.0087 0.053
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0276 0.1638 0.1638
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0156 0.0245
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0043 0.0195 0.0195
Schistosoma mansoni rab6-interacting 0.0039 0.0174 0.0371
Plasmodium falciparum glutathione reductase 0.0038 0.0166 0.0284
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0065 0.0333 0.0547
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0039 0.0066
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0018 0.0041 0.0088
Onchocerca volvulus 0.0045 0.0209 0.1337
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0036 0.0154 0.0262
Loa Loa (eye worm) beta-lactamase 0.0036 0.0156 0.0415
Trypanosoma brucei pteridine reductase 1 0.0065 0.0333 1
Schistosoma mansoni GTP-binding protein alpha subunit 0.0012 0.0005 0.001
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0276 0.1638 0.3504
Brugia malayi Guanine nucleotide-binding protein alpha-6 subunit, putative 0.0012 0.0005 0.0028
Toxoplasma gondii 3-ketoacyl-(acyl-carrier-protein) reductase 0.0065 0.0333 0.0568
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0013 0.0013 0.0022
Mycobacterium ulcerans short chain dehydrogenase 0.0065 0.0333 0.0547
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0618 0.3753 1
Echinococcus multilocularis GPCR, family 2 0.0049 0.0234 0.0234
Loa Loa (eye worm) guanine nucleotide-binding protein alpha-6 subunit 0.0012 0.0005 0.0012
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0171 0.099 0.2117
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0156 0.0245
Mycobacterium tuberculosis Probable reductase 0.0087 0.0467 0.0777
Mycobacterium leprae Probable lipase LipE 0.0036 0.0156 0.0044
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0014 0.0018 0.0031
Mycobacterium ulcerans lipase LipD 0.0036 0.0156 0.0245
Brugia malayi hypothetical protein 0.0012 0.0005 0.0028
Schistosoma mansoni GTP-binding protein alpha subunit 0.0012 0.0005 0.001
Echinococcus granulosus peregrin 0.003 0.0114 0.0245
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0087 0.0148
Giardia lamblia PHD finger protein 15 0.003 0.0114 0.5585
Treponema pallidum NADH oxidase 0.0013 0.0013 0.5
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0013 0.0013 0.0022
Schistosoma mansoni lipoxygenase 0.0101 0.0553 0.1184
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0959 0.5861 1
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0043 0.0195 0.1189
Brugia malayi Guanine nucleotide-binding protein alpha-12 subunit, putative 0.0012 0.0005 0.0028
Leishmania major importin beta-1 subunit, putative 0.0047 0.0222 0.6524
Leishmania major dehydrogenase/oxidoreductase-like protein 0.0065 0.0333 1
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0087 0.0467 0.0777
Loa Loa (eye worm) hypothetical protein 0.003 0.0114 0.0305
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0017 0.0039 0.0066
Loa Loa (eye worm) hypothetical protein 0.015 0.0859 0.2288
Mycobacterium ulcerans 3-ketoacyl-ACP reductase 0.0065 0.0333 0.0547
Schistosoma mansoni hypothetical protein 0.0049 0.0234 0.05
Trichomonas vaginalis GTP-binding protein (q) alpha-11 subunit, gna11, putative 0.0012 0.0005 0.0008
Echinococcus multilocularis importin subunit beta 1 0.0058 0.0289 0.0289
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0174 0.0174
Loa Loa (eye worm) hypothetical protein 0.003 0.0116 0.0308
Echinococcus granulosus geminin 0.0336 0.2012 0.4303
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0156 0.0415
Echinococcus multilocularis GA binding protein alpha chain 0.0073 0.0383 0.0383
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.014 0.0239

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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