Detailed information for compound 793348

Basic information

Technical information
  • TDR Targets ID: 793348
  • Name: 4-chloro-N-[3-(1-prop-2-enylbenzimidazol-2-yl )propyl]benzamide
  • MW: 353.845 | Formula: C20H20ClN3O
  • H donors: 1 H acceptors: 2 LogP: 4.44 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCn1c(CCCNC(=O)c2ccc(cc2)Cl)nc2c1cccc2
  • InChi: 1S/C20H20ClN3O/c1-2-14-24-18-7-4-3-6-17(18)23-19(24)8-5-13-22-20(25)15-9-11-16(21)12-10-15/h2-4,6-7,9-12H,1,5,8,13-14H2,(H,22,25)
  • InChiKey: VNWWEBWMXIJOCB-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-[3-(1-allylbenzimidazol-2-yl)propyl]-4-chloro-benzamide
  • N-[3-(1-allyl-2-benzimidazolyl)propyl]-4-chlorobenzamide
  • ST5116656
  • ZINC02721550

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) flap endonuclease-1 0.0026 0.0151 0.052
Brugia malayi PHD-finger family protein 0.0011 0.0007 0.0024
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0049 0.0049
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.0059 0.0471 0.1073
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0011 0.0004 0.0014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0004 0.0004
Plasmodium vivax importin-beta 2, putative 0.0029 0.0174 0.1802
Toxoplasma gondii ABC1 family protein 0.0111 0.0967 1
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0049 0.0049
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0285 0.1024
Brugia malayi isocitrate dehydrogenase 0.0016 0.0049 0.0169
Loa Loa (eye worm) hypothetical protein 0.0062 0.0501 0.1725
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0004 0.0014
Plasmodium vivax flap endonuclease 1, putative 0.0026 0.0151 0.1562
Schistosoma mansoni patched 1 0.0044 0.0326 0.0326
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0174 0.0729
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0014
Schistosoma mansoni hypothetical protein 0.0098 0.0848 0.0848
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.002 0.0088 0.0007
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0011 0.0004 0.0004
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0049 0.0508
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0088 0.0297
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0471 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0311 0.2902 0.9987
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0285 0.6046
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0088 0.0297
Brugia malayi Muscleblind-like protein 0.0311 0.2905 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.0967 0.3329
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0098 0.0848 0.0848
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0014
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0016 0.0049 0.0101
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0122 0.0181
Schistosoma mansoni flap endonuclease-1 0.0024 0.0127 0.0127
Trypanosoma brucei unspecified product 0.002 0.0088 0.0297
Schistosoma mansoni hypothetical protein 0.0043 0.031 0.031
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0098 0.0848 0.2919
Toxoplasma gondii histone lysine methyltransferase SET1 0.0053 0.0409 0.4229
Schistosoma mansoni hypothetical protein 0.0043 0.031 0.031
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0299
Loa Loa (eye worm) RGS-3 protein 0.002 0.0087 0.0299
Plasmodium falciparum ATP-dependent 6-phosphofructokinase 0.0059 0.0471 1
Echinococcus multilocularis snurportin 1 0.0305 0.2852 0.2852
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0514 0.0514
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0262 0.0262
Echinococcus granulosus Niemann Pick C1 protein 0.0103 0.0895 0.0895
Mycobacterium ulcerans beta-lactamase 0.0111 0.0967 0.4547
Entamoeba histolytica hypothetical protein 0.0023 0.0122 0.0181
Schistosoma mansoni coup transcription factor 0.0011 0.0004 0.0004
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0174 0.0729
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.002 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.003 0.0186 0.0639
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.002 0.0088 0.0198
Brugia malayi 6-phosphofructokinase 0.022 0.2022 0.6959
Trichomonas vaginalis flap endonuclease-1, putative 0.0026 0.0151 0.0332
Echinococcus granulosus GPCR family 2 0.0098 0.0848 0.0848
Loa Loa (eye worm) latrophilin receptor protein 2 0.0098 0.0848 0.2919
Mycobacterium ulcerans 6-phosphofructokinase 0.022 0.2022 1
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.2022 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0849 0.0849
Onchocerca volvulus 0.0111 0.0967 0.6282
Entamoeba histolytica hypothetical protein 0.0041 0.0298 0.109
Onchocerca volvulus 0.0111 0.0967 0.6282
Entamoeba histolytica Ran family GTPase 0.0021 0.0101 0.0074
Brugia malayi Bromodomain containing protein 0.003 0.0186 0.0639
Echinococcus multilocularis dna polymerase eta 0.002 0.0088 0.0088
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0011 0.0004 0.0004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0016 0.0049 0.0049
Plasmodium vivax hypothetical protein, conserved 0.0111 0.0967 1
Treponema pallidum sodium- and chloride- dependent transporter 0.0062 0.0501 0.1244
Loa Loa (eye worm) hypothetical protein 0.002 0.0088 0.0304
Brugia malayi jmjC domain containing protein 0.0098 0.0841 0.2894
Giardia lamblia Pyrophosphate-fructose 6-phosphate 1-phosphotransferase alpha subunit 0.0059 0.0471 1
Brugia malayi DnaJ domain containing protein 0.0063 0.0512 0.1761
Brugia malayi Sodium:neurotransmitter symporter family protein 0.0062 0.0501 0.1725
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0804 0.7677 0.7677
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0004 0.0014
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0088 0.0198
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0014
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0087 0.0087
Trypanosoma cruzi ATP-dependent 6-phosphofructokinase, glycosomal 0.022 0.2022 1
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0174 0.0174
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0011 0.0004 0.0004
Echinococcus multilocularis 6 phosphofructokinase 0.022 0.2022 0.2022
Echinococcus granulosus dnaJ subfamily C 6 0.0063 0.0512 0.0512
Schistosoma mansoni nuclear hormone receptor 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0299
Schistosoma mansoni ap endonuclease 0.004 0.0285 0.0285
Echinococcus multilocularis isocitrate dehydrogenase 0.0016 0.0049 0.0049
Schistosoma mansoni RAR-like nuclear receptor 0.0011 0.0004 0.0004
Loa Loa (eye worm) solute carrier family 6 member 4 0.0062 0.0501 0.1725
Loa Loa (eye worm) serotonin transporter b 0.0062 0.0501 0.1725
Brugia malayi RNA, U transporter 1 0.0081 0.0684 0.2356
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0011 0.0004 0.0014
Echinococcus granulosus dna polymerase eta 0.002 0.0088 0.0088
Schistosoma mansoni ran 0.0021 0.0101 0.0101
Mycobacterium ulcerans esterase/lipase LipP 0.0111 0.0967 0.4547
Brugia malayi photoreceptor-specific nuclear receptor 0.0011 0.0004 0.0014
Schistosoma mansoni regulator of G protein signaling 0.002 0.0087 0.0087
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.004 0.0285 0.1285
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0011 0.0004 0.0014
Schistosoma mansoni ap endonuclease 0.004 0.0285 0.0285
Schistosoma mansoni 6-phosphofructokinase 0.022 0.2022 0.2022
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0098 0.0841 0.0841
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0088 0.0297
Brugia malayi 6-phosphofructokinase 0.022 0.2022 0.6959
Echinococcus granulosus GTP binding nuclear protein Ran 0.0021 0.0101 0.0101
Brugia malayi latrophilin 2 splice variant baaae 0.0212 0.1951 0.6716
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0011 0.0004 0.0014
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0011 0.0004 0.0004
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0004 0.0014
Echinococcus multilocularis muscleblind protein 0.0311 0.2905 0.2905
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0011 0.0004 0.0014
Schistosoma mansoni regulator of G protein signaling 0.002 0.0087 0.0087
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0088 0.0297
Onchocerca volvulus 0.0062 0.0501 0.3254
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0011 0.0004 0.0004
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0514 0.0514
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0087 0.0087
Entamoeba histolytica exodeoxyribonuclease III, putative 0.004 0.0285 0.1024
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0471 0.1987
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.2022 1
Echinococcus multilocularis beta adrenergic receptor kinase 0.002 0.0087 0.0087
Brugia malayi A-kinase anchor protein 10, precursor 0.002 0.0087 0.0299
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0004 0.0004
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0011 0.0004 0.0014
Schistosoma mansoni sodium/chloride dependent transporter 0.0062 0.0501 0.0501
Onchocerca volvulus Alhambra homolog 0.003 0.0186 0.1205
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0088 0.0297
Echinococcus multilocularis Niemann Pick C1 protein 0.0147 0.1323 0.1323
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0087 0.0087
Echinococcus granulosus FTZ F1 alpha 0.043 0.4058 0.4058
Brugia malayi exodeoxyribonuclease III family protein 0.004 0.0285 0.0981
Schistosoma mansoni terminal deoxycytidyl transferase 0.002 0.0088 0.0088
Brugia malayi nuclear receptor NHR-88 0.0011 0.0004 0.0014
Giardia lamblia GTP-binding nuclear protein RAN/TC4 0.0021 0.0101 0.0339
Plasmodium falciparum flap endonuclease 1 0.0026 0.0151 0.3205
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0111 0.0967 0.3329
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0041 0.0298 0.0298
Plasmodium falciparum importin beta, putative 0.0029 0.0174 0.3696
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0098 0.0848 0.0848
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0849 0.0849
Brugia malayi F/Y-rich N-terminus family protein 0.0018 0.0074 0.0255
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.0122 0.0122
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.002 0.0087 0.0299
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0088 0.0297
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0041 0.0298 0.0298
Loa Loa (eye worm) PHD-finger family protein 0.003 0.0186 0.0639
Schistosoma mansoni hypothetical protein 0.0023 0.0122 0.0122
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0514 0.0514
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.0849 0.2922
Echinococcus granulosus jumonji domain containing protein 0.0041 0.0298 0.0298
Entamoeba histolytica phosphofructokinase, putative 0.022 0.2022 1
Schistosoma mansoni hypothetical protein 0.0041 0.0298 0.0298
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0299
Echinococcus multilocularis Niemann Pick C1 protein 0.0103 0.0895 0.0895
Brugia malayi RNA recognition motif domain containing protein 0.0064 0.0514 0.177
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.002 0.0088 0.0058
Trichomonas vaginalis conserved hypothetical protein 0.0044 0.0326 0.1233
Schistosoma mansoni hypothetical protein 0.0212 0.1951 0.1951
Echinococcus granulosus snurportin 1 0.0305 0.2852 0.2852
Toxoplasma gondii 6-phosphofructokinase 0.0059 0.0471 0.4874
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0111 0.0967 0.3329
Echinococcus multilocularis regulator of G protein signaling 3 0.002 0.0087 0.0087
Trichomonas vaginalis 6-phosphofructokinase, putative 0.0059 0.0471 0.1987
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0471 0.1987
Loa Loa (eye worm) 6-phosphofructokinase 0.022 0.2022 0.6959
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.002 0.0087 0.0299
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0004 0.0004
Schistosoma mansoni norepinephrine/norepinephrine transporter 0.0062 0.0501 0.0501
Brugia malayi PHD-finger family protein 0.003 0.0186 0.0639
Echinococcus granulosus Niemann Pick C1 protein 0.0147 0.1323 0.1323
Brugia malayi hypothetical protein 0.0033 0.0221 0.0759
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0011 0.0004 0.0014
Echinococcus multilocularis GPCR, family 2 0.0098 0.0848 0.0848
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0706 0.6732 1
Loa Loa (eye worm) DnaJ domain-containing protein 0.0063 0.0512 0.1761
Echinococcus granulosus 6 phosphofructokinase 0.022 0.2022 0.2022
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0471 0.4874
Loa Loa (eye worm) hypothetical protein 0.0011 0.0007 0.0024
Echinococcus granulosus flap endonuclease 1 0.0026 0.0151 0.0151
Brugia malayi regulator of G-protein signaling rgs-7 0.002 0.0087 0.0299
Echinococcus granulosus sterol regulatory element binding protein 0.0044 0.0326 0.0326
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.002 0.0088 0.0088
Brugia malayi hypothetical protein 0.017 0.154 0.53
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0168 0.0577
Plasmodium vivax hypothetical protein, conserved 0.003 0.0186 0.1918
Schistosoma mansoni hypothetical protein 0.003 0.0186 0.0186
Echinococcus granulosus PHD finger protein rhinoceros 0.003 0.0186 0.0186
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0186 0.1918
Treponema pallidum diphosphate--fructose-6-phosphate 1-phosphotransferase 0.022 0.2022 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.0967 0.3329
Mycobacterium tuberculosis Probable esterase LipL 0.0111 0.0967 0.1374
Schistosoma mansoni hypothetical protein 0.0043 0.031 0.031
Mycobacterium leprae PROBABLE 6-PHOSPHOFRUCTOKINASE PFKA (PHOSPHOHEXOKINASE) (PHOSPHOFRUCTOKINASE) 0.022 0.2022 1
Trypanosoma brucei DNA polymerase IV, putative 0.002 0.0088 0.0297
Toxoplasma gondii exonuclease III APE 0.004 0.0285 0.2947
Entamoeba histolytica hypothetical protein 0.0041 0.0298 0.109
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0026 0.0151 0.1562
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0471 0.1987
Schistosoma mansoni DNA polymerase eta 0.002 0.0088 0.0088
Echinococcus granulosus expressed conserved protein 0.0097 0.0834 0.0834
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0111 0.0967 0.4547
Echinococcus multilocularis microtubule associated protein 2 0.0684 0.6518 0.6518
Echinococcus multilocularis Regulator of G protein signaling 20 0.002 0.0087 0.0087
Echinococcus granulosus tar DNA binding protein 0.0064 0.0514 0.0514
Loa Loa (eye worm) RNA binding protein 0.0064 0.0514 0.177
Plasmodium falciparum GTP-binding nuclear protein RAN/TC4 0.0021 0.0101 0.2147
Echinococcus granulosus ecdysone induced protein 78C 0.0011 0.0004 0.0004
Trypanosoma cruzi importin beta-1 subunit, putative 0.0023 0.0122 0.0369
Schistosoma mansoni steroid hormone receptor ad4bp 0.0011 0.0004 0.0004
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.004 0.0285 0.0285
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0299
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.002 0.0088 0.0304
Echinococcus multilocularis regulator of G protein signaling 0.002 0.0087 0.0087
Schistosoma mansoni hypothetical protein 0.0098 0.0848 0.0848
Leishmania major importin beta-1 subunit, putative 0.0023 0.0122 0.0369
Loa Loa (eye worm) beta-lactamase 0.0111 0.0967 0.3329
Echinococcus multilocularis ecdysone induced protein 78C 0.0011 0.0004 0.0004
Echinococcus multilocularis FTZ F1 alpha 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.017 0.154 0.53
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.002 0.0087 0.0087
Echinococcus granulosus Regulator of G protein signaling 20 0.002 0.0087 0.0087
Brugia malayi CHE-14 protein 0.0044 0.0326 0.1121
Onchocerca volvulus 0.017 0.154 1
Onchocerca volvulus 0.0011 0.0004 0.0027
Trypanosoma cruzi DNA polymerase eta, putative 0.002 0.0088 0.0198
Trichomonas vaginalis ap endonuclease, putative 0.004 0.0285 0.1024
Giardia lamblia Flap structure-specific endonuclease 0.0026 0.0151 0.1641
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0087 0.0087
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0059 0.047 0.047
Echinococcus multilocularis expressed conserved protein 0.0097 0.0834 0.0834
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0398 0.1768
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0011 0.0004 0.0014
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.004 0.0285 0.0981
Echinococcus multilocularis tar DNA binding protein 0.0064 0.0514 0.0514
Echinococcus multilocularis PHD finger protein rhinoceros 0.003 0.0186 0.0186
Loa Loa (eye worm) GTP-binding nuclear protein RAN/TC4 0.0021 0.0101 0.0348
Loa Loa (eye worm) hypothetical protein 0.0051 0.0391 0.1347
Toxoplasma gondii GTP-binding nuclear protein ran/tc4 0.0021 0.0101 0.1046
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0087 0.0087
Schistosoma mansoni transcription factor LCR-F1 0.0041 0.0298 0.0298
Brugia malayi Calcitonin receptor-like protein seb-1 0.0311 0.2902 0.9987
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0014
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.2022 1
Onchocerca volvulus Protein ultraspiracle homolog 0.0011 0.0004 0.0027
Echinococcus multilocularis GTP binding nuclear protein Ran 0.0021 0.0101 0.0101
Entamoeba histolytica Flap nuclease, putative 0.0026 0.0151 0.0332
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0011 0.0008 0.0173
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0016 0.0049 0.0049
Echinococcus multilocularis cpg binding protein 0.0029 0.0183 0.0183
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0967 0.4655
Echinococcus multilocularis expressed protein 0.0381 0.3585 0.3585
Brugia malayi Latrophilin receptor protein 2 0.0098 0.0848 0.2919
Schistosoma mansoni z-protein (S1r protein) 0.002 0.0087 0.0087
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0103 0.0895 0.4176
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0011 0.0004 0.0004
Loa Loa (eye worm) phosphofructokinase 0.022 0.2022 0.6959
Loa Loa (eye worm) hypothetical protein 0.0062 0.0501 0.1725
Schistosoma mansoni hypothetical protein 0.0043 0.031 0.031
Echinococcus multilocularis peregrin 0.003 0.0186 0.0186
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0471 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0004 0.0014
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0011 0.0004 0.0004
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0305 0.2852 0.9815
Trichomonas vaginalis DNA polymerase eta, putative 0.002 0.0088 0.0007
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.004 0.0285 0.1196
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0849 0.0849
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0088 0.0297
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0088 0.0304
Trichomonas vaginalis esterase, putative 0.0111 0.0967 0.455
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0105 0.091 0.091
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0016 0.0049 0.1042
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.004 0.0285 0.0285
Loa Loa (eye worm) PXA domain-containing protein 0.002 0.0087 0.0299
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.0849 0.0849
Loa Loa (eye worm) hypothetical protein 0.0111 0.0967 0.3329
Brugia malayi phosphofructokinase 0.022 0.2022 0.6959
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0004 0.0004
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0087 0.0087
Echinococcus granulosus cpg binding protein 0.0029 0.0183 0.0183
Trypanosoma brucei GTP-binding nuclear protein rtb2, putative 0.0021 0.0101 0.0362
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.004 0.0285 0.1196
Brugia malayi hypothetical protein 0.0052 0.0398 0.137
Echinococcus multilocularis geminin 0.1044 1 1
Schistosoma mansoni hypothetical protein 0.0098 0.0848 0.0848
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0087 0.0299
Trichomonas vaginalis Importin beta-1 subunit, putative 0.0023 0.0122 0.0181
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.004 0.0285 0.1196
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0026 0.0151 0.0517
Entamoeba histolytica pyrophosphate-dependent phosphofructokinase 0.0059 0.0471 0.1987
Schistosoma mansoni cpg binding protein 0.0029 0.0183 0.0183
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.0849 0.2922
Brugia malayi Importin beta-1 subunit 0.0029 0.0174 0.06
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.004 0.0285 0.5136
Echinococcus granulosus expressed protein 0.0381 0.3585 0.3585
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0471 0.1987
Echinococcus granulosus microtubule associated protein 2 0.0684 0.6518 0.6518
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0967 0.455
Toxoplasma gondii phosphofructokinase domain-containing protein 0.0059 0.0471 0.4874
Trichomonas vaginalis phosphofructokinase, putative 0.022 0.2022 1
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0011 0.0004 0.0014
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0514 0.0514
Echinococcus granulosus muscleblind protein 0.0311 0.2905 0.2905
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0011 0.0006 0.0006
Trichomonas vaginalis protein kinase inhibitor, putative 0.0063 0.0512 0.2196
Mycobacterium ulcerans hypothetical protein 0.0111 0.0967 0.4547
Schistosoma mansoni hypothetical protein 0.0397 0.3743 0.3743
Toxoplasma gondii isocitrate dehydrogenase 0.0016 0.0049 0.0508
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0016 0.0049 0.0508
Schistosoma mansoni hypothetical protein 0.0063 0.0512 0.0512
Brugia malayi beta-lactamase family protein 0.0111 0.0967 0.3329
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.002 0.0088 0.0088
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0849 0.0849
Toxoplasma gondii PHD-finger domain-containing protein 0.003 0.0186 0.1918
Mycobacterium tuberculosis Probable lipase LipE 0.0111 0.0967 0.1374
Brugia malayi MH2 domain containing protein 0.013 0.1156 0.3979
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0111 0.0967 0.1374
Loa Loa (eye worm) hypothetical protein 0.0044 0.0326 0.1121
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.002 0.0088 0.0088
Brugia malayi ImpB/MucB/SamB family protein 0.002 0.0088 0.0304
Loa Loa (eye worm) hypothetical protein 0.0111 0.0967 0.3329
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0014
Echinococcus multilocularis serotonin transporter 0.0062 0.0501 0.0501
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0011 0.0004 0.0014
Brugia malayi ecdysteroid receptor 0.0011 0.0004 0.0014
Schistosoma mansoni ran 0.0021 0.0101 0.0101
Schistosoma mansoni hypothetical protein 0.1044 1 1
Loa Loa (eye worm) norepinephrine transporter 0.0062 0.0501 0.1725
Loa Loa (eye worm) jmjC domain-containing protein 0.0061 0.0492 0.1694
Echinococcus granulosus importin subunit beta 1 0.0029 0.0174 0.0174
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0011 0.0004 0.0014
Brugia malayi hypothetical protein 0.002 0.0087 0.0299
Echinococcus granulosus axis inhibition protein axin 0.002 0.0087 0.0087
Schistosoma mansoni axis inhibition protein axin 0.002 0.0087 0.0087
Echinococcus multilocularis protein patched 0.0044 0.0326 0.0326
Entamoeba histolytica hypothetical protein 0.0041 0.0298 0.109
Mycobacterium tuberculosis Conserved protein 0.0111 0.0967 0.1374
Echinococcus multilocularis flap endonuclease 1 0.0026 0.0151 0.0151
Loa Loa (eye worm) jmjC domain-containing protein 0.0038 0.0262 0.09
Mycobacterium tuberculosis Conserved protein 0.0111 0.0967 0.1374
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0967 0.0967
Echinococcus multilocularis lysine specific demethylase 5A 0.0036 0.0246 0.0246
Mycobacterium tuberculosis Probable 6-phosphofructokinase PfkA (phosphohexokinase) (phosphofructokinase) 0.022 0.2022 0.2952
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.002 0.0087 0.0087
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0111 0.0967 0.0967
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0011 0.0004 0.0004
Brugia malayi Isocitrate dehydrogenase 0.0016 0.0049 0.0169
Echinococcus granulosus lysine specific demethylase 5A 0.0038 0.0262 0.0262
Leishmania major DNA polymerase kappa, putative 0.002 0.0088 0.0198
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0101 0.0264
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0098 0.0841 0.0841
Brugia malayi regulator of G-protein signaling egl-10 0.002 0.0087 0.0299
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.0122 0.0122
Giardia lamblia PHD finger protein 15 0.003 0.0186 0.2541
Trypanosoma cruzi GTP-binding nuclear protein rtb2, putative 0.0021 0.0101 0.0264
Loa Loa (eye worm) transcription factor SMAD2 0.013 0.1156 0.3979
Brugia malayi nuclear hormone receptor 0.0011 0.0004 0.0014
Leishmania major DNA polymerase eta, putative 0.002 0.0088 0.0198
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0111 0.0967 0.3329
Schistosoma mansoni tar DNA-binding protein 0.0064 0.0514 0.0514
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0111 0.0967 0.1374
Plasmodium vivax 6-phosphofructokinase, putative 0.0059 0.0471 0.4874
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0011 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0111 0.0967 0.3329
Brugia malayi CXXC zinc finger family protein 0.0028 0.0168 0.0577
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0011 0.0004 0.0014
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.002 0.0087 0.0299
Echinococcus multilocularis sterol regulatory element binding protein 0.0044 0.0326 0.0326
Trypanosoma brucei PAB1-binding protein , putative 0.0052 0.0398 0.1851
Trypanosoma brucei ATP-dependent 6-phosphofructokinase, glycosomal 0.022 0.2022 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0064 0.0514 0.177
Echinococcus multilocularis dnaJ subfamily C 6 0.0063 0.0512 0.0512
Schistosoma mansoni cpg binding protein 0.0029 0.0183 0.0183
Plasmodium falciparum phd finger protein, putative 0.003 0.0186 0.3936
Schistosoma mansoni microtubule-associated protein tau 0.0684 0.6518 0.6518
Echinococcus granulosus beta-adrenergic receptor kinase 0.002 0.0087 0.0087
Toxoplasma gondii LsmAD domain-containing protein 0.0052 0.0398 0.4114
Entamoeba histolytica deoxycytidyl transferase, putative 0.002 0.0088 0.0007
Trypanosoma brucei hypothetical protein, conserved 0.0111 0.0967 0.4708
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0016 0.0049 0.0101
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.003 0.0186 0.0186
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0011 0.0004 0.0014
Trypanosoma brucei DNA polymerase eta, putative 0.002 0.0088 0.0297
Brugia malayi beta-lactamase 0.0111 0.0967 0.3329
Loa Loa (eye worm) hypothetical protein 0.0311 0.2902 0.9987
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0011 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0098 0.0848 0.0848
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0044 0.0326 0.1121
Brugia malayi jmjC domain containing protein 0.0038 0.0262 0.09
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.0849 0.0849
Entamoeba histolytica phosphofructokinase, putative 0.022 0.2022 1
Plasmodium vivax ataxin-2 like protein, putative 0.0052 0.0398 0.4114
Onchocerca volvulus Bile acid receptor homolog 0.0011 0.0004 0.0027
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0088 0.0297
Schistosoma mansoni hypothetical protein 0.0305 0.2852 0.2852
Schistosoma mansoni regulator of G protein signaling 0.002 0.0087 0.0087
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0398 0.8441
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0471 0.1987
Leishmania major hypothetical protein, conserved 0.0111 0.0967 0.4655
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0011 0.0004 0.0014
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0111 0.0967 0.1374
Plasmodium vivax GTP-binding nuclear protein RAN/TC4, putative 0.0021 0.0101 0.1046
Brugia malayi TAR-binding protein 0.0064 0.0514 0.177
Onchocerca volvulus 0.0028 0.0168 0.1088
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0011 0.0004 0.0027
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0299
Leishmania major GTP-binding protein, putative 0.0021 0.0101 0.0264
Onchocerca volvulus 0.0111 0.0967 0.6282
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0011 0.0004 0.0004
Echinococcus multilocularis beta LACTamase domain containing family member 0.0111 0.0967 0.0967
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0011 0.0006 0.0006
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.004 0.0285 0.2947
Echinococcus multilocularis regulator of G protein signaling 7 0.002 0.0087 0.0087
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0011 0.0004 0.0004
Plasmodium falciparum ataxin-2 like protein, putative 0.0052 0.0398 0.8441
Loa Loa (eye worm) MH2 domain-containing protein 0.013 0.1156 0.3979
Plasmodium vivax hypothetical protein, conserved 0.0011 0.0008 0.0084
Toxoplasma gondii phosphofructokinase PFKII 0.0059 0.0471 0.4874
Loa Loa (eye worm) hypothetical protein 0.0103 0.0895 0.308
Loa Loa (eye worm) TAR-binding protein 0.0064 0.0514 0.177
Trichomonas vaginalis importin beta-1, putative 0.0023 0.0122 0.0181
Loa Loa (eye worm) steroid hormone receptor 0.0011 0.0004 0.0014
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0011 0.0004 0.0004
Echinococcus multilocularis jumonji domain containing protein 0.0041 0.0298 0.0298
Schistosoma mansoni 6-phosphofructokinase 0.022 0.2022 0.2022
Chlamydia trachomatis fructose-6-phosphate phosphotransferase 0.0059 0.0471 1
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0026 0.0151 0.0612
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0011 0.0004 0.0014
Echinococcus multilocularis dna polymerase kappa 0.002 0.0088 0.0088
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0088 0.0198
Loa Loa (eye worm) 6-phosphofructokinase 0.022 0.2022 0.6959
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.0849 0.0849
Brugia malayi GTP-binding nuclear protein RAN/TC4 0.0021 0.0101 0.0348
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0088 0.0297
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0087 0.0087
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0026 0.0151 0.0517
Echinococcus granulosus dna polymerase kappa 0.002 0.0088 0.0088
Mycobacterium tuberculosis Conserved protein 0.0111 0.0967 0.1374
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.004 0.0285 0.0353
Entamoeba histolytica hypothetical protein 0.0041 0.0298 0.109
Trichomonas vaginalis ran, putative 0.0021 0.0101 0.0074
Brugia malayi PXA domain containing protein 0.002 0.0087 0.0299
Brugia malayi steroid hormone receptor 0.0011 0.0004 0.0014
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.004 0.0285 0.5
Schistosoma mansoni jumonji/arid domain-containing protein 0.0038 0.0262 0.0262
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0016 0.0049 0.0049
Schistosoma mansoni jumonji domain containing protein 0.0077 0.0647 0.0647
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0311 0.2902 0.9987
Echinococcus granulosus dnaJ subfamily B 0.0397 0.3743 0.3743
Loa Loa (eye worm) hypothetical protein 0.0052 0.0398 0.137
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0088 0.0297
Echinococcus granulosus axis inhibition protein axin 0.002 0.0087 0.0087
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0014
Mycobacterium ulcerans lipase LipD 0.0111 0.0967 0.4547
Loa Loa (eye worm) hypothetical protein 0.002 0.0087 0.0299
Brugia malayi RNA binding protein 0.0064 0.0514 0.177
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.004 0.0285 0.1018
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0967 0.455
Echinococcus granulosus regulator of G protein signaling 7 0.002 0.0087 0.0087
Leishmania major ATP-dependent phosphofructokinase 0.022 0.2022 1
Loa Loa (eye worm) hypothetical protein 0.0311 0.2905 1
Echinococcus granulosus serotonin transporter 0.0062 0.0501 0.0501
Brugia malayi Regulator of G protein signaling domain containing protein 0.002 0.0087 0.0299
Echinococcus multilocularis dnaJ subfamily B 0.0397 0.3743 0.3743
Trichomonas vaginalis penicillin-binding protein, putative 0.0111 0.0967 0.455
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0088 0.0198
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0088 0.0297
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0017 0.0059 0.0059
Schistosoma mansoni importin beta-1 0.0029 0.0174 0.0174
Trichomonas vaginalis phosphofructokinase, putative 0.0059 0.0471 0.1987
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0174 0.1802
Trypanosoma cruzi PAB1-binding protein , putative 0.0052 0.0398 0.1768
Loa Loa (eye worm) isocitrate dehydrogenase 0.0016 0.0049 0.0169
Brugia malayi Niemann-Pick C1 protein precursor 0.0103 0.0895 0.308
Schistosoma mansoni axis inhibition protein axin 0.002 0.0087 0.0087
Echinococcus granulosus peregrin 0.003 0.0186 0.0186
Mycobacterium tuberculosis Probable hydrolase 0.0111 0.0967 0.1374
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0098 0.0848 0.0848
Echinococcus multilocularis protein dispatched 1 0.005 0.0386 0.0386
Trypanosoma cruzi hypothetical protein, conserved 0.0111 0.0967 0.4655
Echinococcus granulosus Protein patched homolog 1 0.0044 0.0326 0.0326
Loa Loa (eye worm) hypothetical protein 0.0212 0.1951 0.6716
Loa Loa (eye worm) hypothetical protein 0.0062 0.0501 0.1725
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0098 0.0848 0.0848
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0011 0.0004 0.0004
Echinococcus granulosus beta LACTamase domain containing family member 0.0111 0.0967 0.0967
Schistosoma mansoni retinoic acid receptor RXR 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0029 0.0174 0.06
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0016 0.0049 0.0049
Schistosoma mansoni hypothetical protein 0.1044 1 1
Leishmania major hypothetical protein, conserved 0.0052 0.0398 0.1768
Brugia malayi beta-lactamase family protein 0.0111 0.0967 0.3329
Echinococcus multilocularis thyroid hormone receptor alpha 0.0011 0.0004 0.0004
Trypanosoma cruzi DNA polymerase kappa, putative 0.002 0.0088 0.0198
Schistosoma mansoni thyroid hormone receptor 0.0011 0.0004 0.0004
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0014
Brugia malayi Steroid receptor seven-up type 2 0.0011 0.0004 0.0014
Brugia malayi hypothetical protein 0.002 0.0087 0.0299
Schistosoma mansoni regulator of G protein signaling 0.002 0.0087 0.0087
Schistosoma mansoni serine/threonine protein kinase 0.002 0.0087 0.0087
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.002 0.0087 0.0299
Echinococcus multilocularis muscleblind protein 1 0.0311 0.2905 0.2905
Mycobacterium tuberculosis Conserved hypothetical protein 0.002 0.0088 0.0058
Mycobacterium tuberculosis Probable lipase LipD 0.0111 0.0967 0.1374
Entamoeba histolytica phosphofructokinase, putative 0.022 0.2022 1
Trypanosoma brucei DNA polymerase kappa, putative 0.002 0.0088 0.0297
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0967 0.455
Brugia malayi PXA domain containing protein 0.002 0.0087 0.0299
Brugia malayi hypothetical protein 0.0041 0.0298 0.1025
Loa Loa (eye worm) hypothetical protein 0.0011 0.0004 0.0014
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.002 0.0087 0.0087
Brugia malayi Flap endonuclease-1 0.0026 0.0151 0.052
Echinococcus multilocularis axis inhibition protein axin 0.002 0.0087 0.0087
Schistosoma mansoni regulator of G protein signaling 0.002 0.0087 0.0087
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0011 0.0004 0.0004
Trichomonas vaginalis D-aminoacylase, putative 0.0111 0.0967 0.455
Echinococcus granulosus regulator of G protein signaling 3 0.002 0.0087 0.0087
Schistosoma mansoni cpg binding protein 0.0028 0.0168 0.0168
Loa Loa (eye worm) hypothetical protein 0.0311 0.2905 1
Loa Loa (eye worm) hypothetical protein 0.0098 0.0848 0.2919
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0011 0.0004 0.0014
Loa Loa (eye worm) hypothetical protein 0.0054 0.0422 0.1452

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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