Detailed information for compound 794315

Basic information

Technical information
  • TDR Targets ID: 794315
  • Name: 1-(2-fluorophenyl)-4-(2-methoxy-5-methylpheny l)sulfonylpiperazine
  • MW: 364.434 | Formula: C18H21FN2O3S
  • H donors: 0 H acceptors: 2 LogP: 3.1 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1S(=O)(=O)N1CCN(CC1)c1ccccc1F)C
  • InChi: 1S/C18H21FN2O3S/c1-14-7-8-17(24-2)18(13-14)25(22,23)21-11-9-20(10-12-21)16-6-4-3-5-15(16)19/h3-8,13H,9-12H2,1-2H3
  • InChiKey: YQPBNKQEZCPNSS-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • 1-(2-fluorophenyl)-4-(2-methoxy-5-methyl-phenyl)sulfonyl-piperazine
  • A2903/0122324
  • Piperazine, 1-(2-fluorophenyl)-4-(2-methoxy-5-methylbenzenesulfonyl)-
  • ZINC01072236

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi beta-lactamase 0.0036 0.0546 0.0808
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0009 0.0009 0.0009
Echinococcus granulosus intermediate filament protein 0.0026 0.0357 0.0357
Brugia malayi exodeoxyribonuclease III family protein 0.0019 0.0213 0.0307
Loa Loa (eye worm) TK/KIN16 protein kinase 0.001 0.0025 0.0024
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0001
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.0088 0.0088
Trichomonas vaginalis DNA helicase recq, putative 0.0014 0.0121 0.2211
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0323 0.5849
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0009 0.0009 0.0009
Brugia malayi hypothetical protein 0.003 0.0425 0.0626
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0019 0.0213 0.4901
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Brugia malayi hypothetical protein 0.0025 0.0323 0.0473
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0001
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0001
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0546 1
Schistosoma mansoni protein-tyrosine phosphatase n9 0.0009 0.0009 0.0009
Schistosoma mansoni vesicular amine transporter 0.0009 0.0009 0.0009
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0546 1
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0011 0.0056 0.0056
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0323 0.5849
Echinococcus granulosus lamin dm0 0.0026 0.0357 0.0357
Echinococcus multilocularis musashi 0.0026 0.0357 0.0357
Echinococcus granulosus twitchin 0.0009 0.0009 0.0009
Mycobacterium ulcerans beta-lactamase 0.0036 0.0546 1
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0121 0.2079
Loa Loa (eye worm) hypothetical protein 0.0036 0.0546 0.0808
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0001
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0213 0.3899
Echinococcus multilocularis bloom syndrome protein 0.0027 0.0369 0.0369
Brugia malayi Protein-tyrosine phosphatase containing protein 0.0344 0.6654 1
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0546 1
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0229 0.4371 1
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0357 0.0524
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0009 0.0009 0.0009
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0009 0.0009 0.0009
Echinococcus multilocularis lamin 0.0026 0.0357 0.0357
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0036 0.0546 0.1249
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Brugia malayi beta-lactamase family protein 0.0036 0.0546 0.0808
Loa Loa (eye worm) hypothetical protein 0.0026 0.0348 0.051
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.003 0.0425 0.0425
Brugia malayi intermediate filament protein 0.0026 0.0357 0.0524
Onchocerca volvulus 0.0036 0.0546 1
Echinococcus granulosus defective proboscis extension response 0.0009 0.0009 0.0009
Mycobacterium tuberculosis Conserved protein 0.0036 0.0546 0.1249
Brugia malayi hypothetical protein 0.0009 0.0009 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0088 0.0118
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0009 0.0009 0.0009
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0009 0.0009 0.0009
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0036 0.0546 0.1249
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0344 0.6654 0.6654
Echinococcus granulosus lamin 0.0026 0.0357 0.0357
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0546 0.0546
Loa Loa (eye worm) hypothetical protein 0.0011 0.0056 0.0071
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0019 0.0213 0.0213
Schistosoma mansoni hypothetical protein 0.0011 0.0055 0.0055
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0546 1
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0019 0.0213 0.3797
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0001
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0009 0.0009 0.0009
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0546 1
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0009 0.0009 0.0009
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0011 0.0056 0.0056
Schistosoma mansoni non-receptor protein-tyrosine phosphatase 0.0009 0.0009 0.0009
Brugia malayi beta-lactamase family protein 0.0036 0.0546 0.0808
Mycobacterium leprae conserved hypothetical protein 0.0036 0.0546 1
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0009 0.0009 0.0009
Echinococcus multilocularis roundabout 2 0.0009 0.0009 0.0009
Echinococcus granulosus macrophage colony stimulating factor 1 receptor 0.0312 0.6019 0.6019
Entamoeba histolytica hypothetical protein 0.003 0.0425 1
Trichomonas vaginalis esterase, putative 0.0036 0.0546 1
Loa Loa (eye worm) hypothetical protein 0.0036 0.0546 0.0808
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0009 0.0009 0.0009
Schistosoma mansoni transcription factor LCR-F1 0.003 0.0425 0.0425
Brugia malayi hypothetical protein 0.0016 0.0151 0.0213
Schistosoma mansoni nephrin 0.0009 0.0009 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.1646 0.1646
Schistosoma mansoni DNA helicase recq5 0.0011 0.0056 0.0056
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0019 0.0213 0.0487
Brugia malayi Bloom's syndrome protein homolog 0.0027 0.0369 0.0541
Loa Loa (eye worm) hypothetical protein 0.0036 0.0546 0.0808
Schistosoma mansoni receptor protein tyrosine phosphatase 0.0009 0.0009 0.0009
Leishmania major hypothetical protein, conserved 0.0025 0.0323 0.5849
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0011 0.0056 0.0071
Onchocerca volvulus 0.0026 0.0357 0.6483
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0546 1
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0001
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0056 0.0000000020432
Schistosoma mansoni hypothetical protein 0.0513 1 1
Mycobacterium tuberculosis Probable lipase LipE 0.0036 0.0546 0.1249
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Loa Loa (eye worm) protein-tyrosine phosphatase 0.0344 0.6654 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0546 0.0546
Onchocerca volvulus 0.0036 0.0546 1
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0357 0.0524
Loa Loa (eye worm) RecQ helicase 0.0027 0.0369 0.0541
Echinococcus multilocularis hypothetical protein 0.0009 0.0009 0.0009
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0091 0.1646 0.2464
Echinococcus granulosus protein tyrosine phosphatase n9 0.0009 0.0009 0.0009
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0009 0.0009 0.0009
Schistosoma mansoni lamin 0.0026 0.0357 0.0357
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0091 0.1646 0.2464
Echinococcus multilocularis basement membrane specific heparan sulfate 0.0009 0.0009 0.0009
Entamoeba histolytica recQ family helicase, putative 0.0014 0.0121 0.2684
Loa Loa (eye worm) hypothetical protein 0.0012 0.0078 0.0104
Mycobacterium tuberculosis Probable esterase LipL 0.0036 0.0546 0.1249
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0036 0.0546 0.1249
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0121 0.2079
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0009 0.0009 0.0009
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0009 0.0009 0.0009
Echinococcus granulosus receptor type tyrosine protein phosphatase zeta 0.0009 0.0009 0.0009
Echinococcus multilocularis receptor type tyrosine protein phosphatase H 0.0009 0.0009 0.0009
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.1646 0.1646
Echinococcus multilocularis 0.0009 0.0009 0.0009
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0323 0.3627
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0019 0.0213 0.3797
Trichomonas vaginalis pten, drome, putative 0.0009 0.0009 0.0166
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0546 0.0546
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0019 0.0213 0.3797
Mycobacterium ulcerans esterase/lipase LipP 0.0036 0.0546 1
Giardia lamblia Sgs1 DNA helicase, putative 0.0011 0.0056 0.2305
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0091 0.1646 0.1646
Schistosoma mansoni cell adhesion molecule 0.0009 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0001
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0546 0.0546
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0019 0.0213 0.3899
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0019 0.0213 1
Echinococcus multilocularis geminin 0.0513 1 1
Schistosoma mansoni defective proboscis extension response (dpr)-related 0.0009 0.0009 0.0009
Echinococcus multilocularis Receptor type tyrosine protein phosphatase O 0.0009 0.0009 0.0009
Schistosoma mansoni rgs-gaip interacting protein gipc 0.0009 0.0009 0.0009
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0115 0.016
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0001
Schistosoma mansoni blooms syndrome DNA helicase 0.0021 0.0257 0.0257
Schistosoma mansoni protein-tyrosine phosphatase non-receptor type nt5 0.0009 0.0009 0.0009
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0323 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0546 0.1249
Schistosoma mansoni ap endonuclease 0.0019 0.0213 0.0213
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0019 0.0213 0.0213
Schistosoma mansoni pcd6 interacting protein-related 0.0009 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0036 0.0546 0.0808
Trichomonas vaginalis ap endonuclease, putative 0.0019 0.0213 0.3899
Echinococcus multilocularis Immunoglobulin 0.0009 0.0009 0.0009
Schistosoma mansoni protein tyrosine phosphatase 0.0009 0.0009 0.0009
Echinococcus multilocularis lamin dm0 0.0026 0.0357 0.0357
Loa Loa (eye worm) hypothetical protein 0.0036 0.0546 0.0808
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0009 0.0009 0.0009
Schistosoma mansoni lamin 0.0026 0.0357 0.0357
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0009 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.003 0.0425 0.0425
Mycobacterium tuberculosis Probable lipase LipD 0.0036 0.0546 0.1249
Echinococcus granulosus Receptor type tyrosine protein phosphatase O 0.0009 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.003 0.0425 1
Mycobacterium tuberculosis Probable hydrolase 0.0036 0.0546 0.1249
Schistosoma mansoni receptor protein tyrosine phosphatase r (pcptp1) 0.0009 0.0009 0.0009
Treponema pallidum exodeoxyribonuclease (exoA) 0.0019 0.0213 1
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0115 0.016
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0018 0.0192 0.2775
Echinococcus multilocularis receptor type tyrosine protein phosphatase F 0.0009 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0012 0.0078 0.0104
Schistosoma mansoni ap endonuclease 0.0019 0.0213 0.0213
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0009 0.0009 0.0009
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0323 0.5849
Echinococcus granulosus roundabout 2 0.0009 0.0009 0.0009
Echinococcus multilocularis neuroglian 0.0009 0.0009 0.0009
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0546 1
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0213 0.5874
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0019 0.0213 0.3797
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.0088 0.0088
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0019 0.0213 0.0307
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0019 0.0213 1
Mycobacterium tuberculosis Conserved protein 0.0036 0.0546 0.1249
Trichomonas vaginalis DNA helicase recq, putative 0.0027 0.0369 0.6753
Trichomonas vaginalis DNA helicase recq1, putative 0.0027 0.0369 0.6753
Onchocerca volvulus 0.0036 0.0546 1
Echinococcus granulosus bloom syndrome protein 0.0027 0.0369 0.0369
Echinococcus granulosus neurotracting:lsamp:neurotrimin:obcam 0.0009 0.0009 0.0009
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0036 0.0546 1
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.1646 0.1646
Toxoplasma gondii exonuclease III APE 0.0019 0.0213 0.3202
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0011 0.0056 0.0056
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0546 0.0808
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Mycobacterium ulcerans hypothetical protein 0.0036 0.0546 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.1646 0.1646
Schistosoma mansoni protein tyrosine phosphatase non-receptor type nt1 0.0344 0.6654 0.6654
Schistosoma mansoni protein tyrosine phosphatase n11 (shp2) 0.0009 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0009 0.0009 0.0001
Echinococcus granulosus Immunoglobulin 0.0009 0.0009 0.0009
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0323 0.5451
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0009 0.0009 0.0009
Loa Loa (eye worm) beta-lactamase 0.0036 0.0546 0.0808
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0011 0.0056 0.0056
Echinococcus multilocularis receptor type tyrosine protein phosphatase zeta 0.0009 0.0009 0.0009
Schistosoma mansoni hypothetical protein 0.0513 1 1
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0019 0.0213 0.0475
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0009 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.003 0.0425 1
Leishmania major hypothetical protein, conserved 0.0036 0.0546 1
Onchocerca volvulus 0.0026 0.0357 0.6483
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0323 1
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0009 0.0009 0.0009
Brugia malayi Immunoglobulin I-set domain containing protein 0.001 0.0025 0.0024
Schistosoma mansoni receptor tyrosine phosphatase type r2a 0.0009 0.0009 0.0009
Echinococcus multilocularis Immunoglobulin 0.0009 0.0009 0.0009
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0091 0.1646 0.1646
Schistosoma mansoni protein tyrosine phosphatase 0.0009 0.0009 0.0009
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0546 0.0808
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0014 0.0121 0.2079
Schistosoma mansoni Neurotrimin precursor (hNT) 0.0009 0.0009 0.0009
Echinococcus granulosus neuroglian 0.0009 0.0009 0.0009
Entamoeba histolytica hypothetical protein 0.003 0.0425 1
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0344 0.6654 0.6654
Schistosoma mansoni protein tyrosine phosphatase 0.0009 0.0009 0.0009
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0357 0.0524
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0546 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase protein tyrosine phosphatase receptor type 0.0009 0.0009 0.0009
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0009 0.0009 0.0009
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0546 1
Schistosoma mansoni DNA helicase recq1 0.0011 0.0056 0.0056
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0091 0.1646 0.1646
Brugia malayi Fibronectin type III domain containing protein 0.0009 0.0009 0.0001
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.003 0.0425 0.0425
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0025 0.0323 0.0473
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0056 0.0071
Schistosoma mansoni receptor protein tyrosine phosphatase n (ia2) 0.0009 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0135 0.2517 0.3774
Toxoplasma gondii ABC1 family protein 0.0036 0.0546 1
Mycobacterium leprae Probable lipase LipE 0.0036 0.0546 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0011 0.0056 0.0071
Echinococcus granulosus receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Loa Loa (eye worm) hypothetical protein 0.0036 0.0546 0.0808
Echinococcus multilocularis protein tyrosine phosphatase n9 0.0009 0.0009 0.0009
Mycobacterium ulcerans lipase LipD 0.0036 0.0546 1
Echinococcus multilocularis receptor type tyrosine protein phosphatase 0.0009 0.0009 0.0009
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0055 0.0055
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0055 0.0055
Brugia malayi Immunoglobulin I-set domain containing protein 0.0009 0.0009 0.0001
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0009 0.0009 0.0009
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0024 0.0304 0.9287
Schistosoma mansoni intermediate filament proteins 0.0026 0.0357 0.0357
Loa Loa (eye worm) hypothetical protein 0.0026 0.0357 0.0524

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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