Detailed information for compound 795163

Basic information

Technical information
  • TDR Targets ID: 795163
  • Name: N-(4-acetylphenyl)-7-methoxy-4,5-dihydrobenzo [g][1,2]benzoxazole-3-carboxamide
  • MW: 362.379 | Formula: C21H18N2O4
  • H donors: 1 H acceptors: 3 LogP: 3.15 Rotable bonds: 5
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc2c(c1)CCc1c2onc1C(=O)Nc1ccc(cc1)C(=O)C
  • InChi: 1S/C21H18N2O4/c1-12(24)13-3-6-15(7-4-13)22-21(25)19-18-9-5-14-11-16(26-2)8-10-17(14)20(18)27-23-19/h3-4,6-8,10-11H,5,9H2,1-2H3,(H,22,25)
  • InChiKey: ZGABLTJNSCTEML-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(4-acetylphenyl)-7-methoxy-4,5-dihydrobenzo[g]indoxazene-3-carboxamide
  • N-(4-ethanoylphenyl)-7-methoxy-4,5-dihydrobenzo[g][1,2]benzoxazole-3-carboxamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Loa Loa (eye worm) CXXC zinc finger family protein 0.0031 0.0134 0.0348
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0245 0.0553
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0243 0.0243
Brugia malayi RNA binding protein 0.0069 0.0651 0.2268
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.4066 1
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0098 0.1045 0.2704
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0039 0.0245 0.0635
Schistosoma mansoni phosphatidylserine receptor 0.0027 0.008 0.008
Plasmodium falciparum importin beta, putative 0.0029 0.0095 0.0215
Echinococcus multilocularis muscleblind protein 1 0.0163 0.1934 0.1934
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0243 0.0422
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0014 0.0035
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.4066 1
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0245 0.0553
Loa Loa (eye worm) RNA binding protein 0.0069 0.0651 0.1684
Onchocerca volvulus 0.0039 0.0243 0.2186
Brugia malayi Glycosyl hydrolases family 31 protein 0.0178 0.2136 0.7444
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0243 0.0547
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0169 0.2008 0.2008
Echinococcus granulosus cpg binding protein 0.0035 0.0187 0.0187
Loa Loa (eye worm) hypothetical protein 0.0039 0.0243 0.0629
Onchocerca volvulus Alhambra homolog 0.0032 0.0141 0.1267
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.4066 1
Brugia malayi PHD-finger family protein 0.0029 0.0102 0.0355
Loa Loa (eye worm) hypothetical protein 0.0039 0.0243 0.0629
Loa Loa (eye worm) hypothetical protein 0.0048 0.0366 0.0949
Brugia malayi Glycosyl hydrolases family 31 protein 0.0039 0.0245 0.0854
Plasmodium falciparum polyubiquitin binding protein, putative 0.0039 0.0243 0.0548
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0243 0.0547
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.1045 0.1045
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0039 0.0245 0.3104
Plasmodium vivax hypothetical protein, conserved 0.0032 0.0141 0.0317
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0026 0.0067 0.0067
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.008 0.0208
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.2136 0.2136
Brugia malayi jmjC domain containing protein 0.0169 0.2008 0.6995
Entamoeba histolytica fatty acid elongase, putative 0.0045 0.032 0.0739
Loa Loa (eye worm) hypothetical protein 0.0032 0.0141 0.0364
Echinococcus granulosus lysine specific demethylase 6a 0.0027 0.008 0.008
Echinococcus multilocularis microtubule associated protein 2 0.0754 1 1
Toxoplasma gondii aldehyde dehydrogenase 0.0066 0.0612 1
Onchocerca volvulus 0.0031 0.0134 0.1208
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.008 0.014
Plasmodium falciparum phd finger protein, putative 0.0032 0.0141 0.0317
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0243 0.0528
Schistosoma mansoni hypothetical protein 0.0023 0.0014 0.0014
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0251 0.3137 0.6899
Brugia malayi F/Y-rich N-terminus family protein 0.0022 0.0007 0.0026
Loa Loa (eye worm) hypothetical protein 0.0163 0.1934 0.5006
Entamoeba histolytica fatty acid elongase, putative 0.0045 0.032 0.0739
Trichomonas vaginalis penicillin-binding protein, putative 0.0039 0.0243 0.0547
Echinococcus multilocularis lysine specific demethylase 5A 0.0103 0.111 0.111
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0612 0.0612
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0141 0.114
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0612 0.0612
Mycobacterium tuberculosis 3-oxoacyl-[acyl-carrier-protein] synthase III FabH (beta-ketoacyl-ACP synthase III) (KAS III) 0.0346 0.4438 1
Echinococcus granulosus alkaline phosphatase 0.0178 0.2132 0.2132
Schistosoma mansoni hypothetical protein 0.0032 0.0141 0.0141
Echinococcus multilocularis lysine specific demethylase 6a 0.0027 0.008 0.008
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0031 0.0133 0.0133
Plasmodium vivax JmjC domain containing protein 0.0027 0.008 0.0181
Plasmodium vivax importin-beta 2, putative 0.0029 0.0095 0.0215
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0156 0.1838 0.4272
Echinococcus granulosus alkaline phosphatase intestinal gene 2 0.0178 0.2132 0.2132
Echinococcus multilocularis snurportin 1 0.0304 0.3864 0.3864
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0651 0.0651
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0156 0.1838 0.4336
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.1045 0.1045
Echinococcus granulosus lysine specific demethylase 5A 0.0107 0.1163 0.1163
Schistosoma mansoni jumonji domain containing protein 0.0027 0.008 0.008
Echinococcus multilocularis zinc finger protein 0.0023 0.0022 0.0022
Echinococcus granulosus neutral alpha glucosidase AB 0.0039 0.0245 0.0245
Brugia malayi jmjC domain containing protein 0.0107 0.1163 0.4051
Leishmania major mitochondrial DNA polymerase beta 0.033 0.4211 1
Trypanosoma brucei glucosidase, putative 0.0039 0.0245 0.0428
Entamoeba histolytica fatty acid elongase, putative 0.0045 0.032 0.0739
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0156 0.1836 1
Brugia malayi RNA recognition motif domain containing protein 0.0069 0.0651 0.2268
Wolbachia endosymbiont of Brugia malayi 3-oxoacyl-ACP synthase 0.0346 0.4438 0.5
Schistosoma mansoni hypothetical protein 0.0092 0.0966 0.0966
Brugia malayi CXXC zinc finger family protein 0.0031 0.0134 0.0468
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0319 0.4066 1
Entamoeba histolytica hypothetical protein 0.0036 0.0192 0.0421
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.033 0.4211 1
Echinococcus granulosus snurportin 1 0.0304 0.3864 0.3864
Brugia malayi jmjC domain containing protein 0.0027 0.008 0.028
Echinococcus multilocularis phospholipase A 2 activating protein 0.0039 0.0243 0.0243
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0098 0.1045 0.1045
Mycobacterium ulcerans hypothetical protein 0.0174 0.2079 0.4376
Trichomonas vaginalis phospholipase A-2-activating protein, putative 0.0027 0.0068 0.0114
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0243 0.0243
Schistosoma mansoni importin beta-1 0.0029 0.0095 0.0095
Schistosoma mansoni cpg binding protein 0.0031 0.0134 0.0134
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.0192 0.0192
Echinococcus multilocularis lysosomal alpha glucosidase 0.0178 0.2136 0.2136
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0612 0.0879
Echinococcus granulosus jumonji domain containing protein 0.0044 0.0311 0.0311
Loa Loa (eye worm) hypothetical protein 0.0077 0.0761 0.1969
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0178 0.2136 0.5529
Echinococcus granulosus zinc finger protein 0.0023 0.0022 0.0022
Loa Loa (eye worm) hypothetical protein 0.0039 0.0243 0.0629
Loa Loa (eye worm) hypothetical protein 0.0029 0.0095 0.0247
Loa Loa (eye worm) hypothetical protein 0.0027 0.008 0.0208
Entamoeba histolytica hypothetical protein 0.0026 0.0057 0.0087
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0095 0.0066
Echinococcus multilocularis jumonji domain containing 1A 0.0027 0.008 0.008
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.0192 0.0192
Brugia malayi Bromodomain containing protein 0.0042 0.0277 0.0966
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0027 0.008 0.014
Echinococcus granulosus neuropeptide receptor A26 0.0507 0.6625 0.6625
Mycobacterium ulcerans beta-ketoacyl synthase-like protein 0.0346 0.4438 1
Schistosoma mansoni cpg binding protein 0.0035 0.0187 0.0187
Schistosoma mansoni phd/f-box containing protein 0.0027 0.008 0.008
Schistosoma mansoni protein phosphatase 2C 0.0027 0.008 0.008
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0066 0.0612 0.0879
Echinococcus granulosus intestinal type alkaline phosphatase 0.0178 0.2132 0.2132
Onchocerca volvulus 0.0039 0.0243 0.2186
Leishmania major hypothetical protein, conserved 0.0039 0.0243 0.0528
Echinococcus multilocularis tar DNA binding protein 0.0069 0.0651 0.0651
Brugia malayi Muscleblind-like protein 0.0163 0.1934 0.674
Brugia malayi TAR-binding protein 0.0069 0.0651 0.2268
Brugia malayi jmjC domain containing protein 0.0027 0.008 0.028
Trypanosoma cruzi WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0039 0.0243 0.0529
Echinococcus multilocularis JmjC domain containing protein 4 0.0027 0.008 0.008
Brugia malayi Bromodomain containing protein 0.0084 0.0849 0.2959
Echinococcus granulosus fetal alzheimer antigen falz 0.0026 0.0067 0.0067
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0319 0.4066 1
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.1045 0.1045
Loa Loa (eye worm) hypothetical protein 0.0027 0.008 0.0208
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0245 0.0553
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0156 0.1836 0.3797
Toxoplasma gondii PHD-finger domain-containing protein 0.0032 0.0141 0.114
Entamoeba histolytica fatty acid elongase, putative 0.0045 0.032 0.0739
Schistosoma mansoni alkaline phosphatase 0.0178 0.2132 0.2132
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0027 0.008 0.008
Toxoplasma gondii HEAT repeat-containing protein 0.0029 0.0095 0.0285
Brugia malayi PHD-finger family protein 0.0032 0.0141 0.0491
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0169 0.2008 0.2008
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0651 0.0651
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0243 0.0547
Plasmodium falciparum JmjC domain-containing protein, putative 0.0027 0.008 0.0181
Schistosoma mansoni jumonji/arid domain-containing protein 0.0107 0.1163 0.1163
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0243 0.0243
Loa Loa (eye worm) nucleolar RNA-associated protein alpha 0.0304 0.3864 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.4066 1
Schistosoma mansoni jumonji domain containing protein 0.0147 0.1715 0.1715
Leishmania major alpha glucosidase II subunit, putative 0.0039 0.0245 0.0533
Leishmania major hypothetical protein, conserved 0.0039 0.0243 0.0529
Plasmodium vivax beta-ketoacyl-acyl carrier protein synthase III precursor, putative 0.0346 0.4438 1
Trichomonas vaginalis phospholipase A-2-activating protein, putative 0.0039 0.0243 0.0548
Schistosoma mansoni jumonji/arid domain-containing protein 0.0107 0.1163 0.1163
Loa Loa (eye worm) TAR-binding protein 0.0069 0.0651 0.1684
Echinococcus multilocularis PHD finger protein rhinoceros 0.0032 0.0141 0.0141
Loa Loa (eye worm) hypothetical protein 0.0042 0.0278 0.072
Schistosoma mansoni hypothetical protein 0.0036 0.0192 0.0192
Entamoeba histolytica fatty acid elongase, putative 0.0045 0.032 0.0739
Brugia malayi hypothetical protein 0.0036 0.0192 0.0669
Echinococcus granulosus JmjC domain containing protein 4 0.0027 0.008 0.008
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.4066 1
Trypanosoma cruzi WD domain, G-beta repeat/PFU (PLAA family ubiquitin binding), putative 0.0039 0.0243 0.0529
Schistosoma mansoni microtubule-associated protein tau 0.0754 1 1
Brugia malayi RNA, U transporter 1 0.0081 0.0813 0.2835
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0651 0.0651
Giardia lamblia Fructose-bisphosphate aldolase 0.0319 0.4066 1
Plasmodium falciparum beta-ketoacyl-ACP synthase III 0.0346 0.4438 1
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0039 0.0242 0.0242
Entamoeba histolytica hypothetical protein 0.0036 0.0192 0.0421
Entamoeba histolytica hypothetical protein 0.0036 0.0192 0.0421
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0245 0.0533
Loa Loa (eye worm) hypothetical protein 0.0039 0.0243 0.0629
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0067 0.0621 0.0621
Echinococcus granulosus muscleblind protein 0.0163 0.1934 0.1934
Echinococcus multilocularis muscleblind protein 0.0163 0.1934 0.1934
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0339 0.0655
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.033 0.4211 1
Chlamydia trachomatis oxoacyl-ACP synthase III 0.0346 0.4438 0.5
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.008 0.0208
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.1045 0.1045
Echinococcus granulosus phospholipase A 2 activating protein 0.0039 0.0243 0.0243
Schistosoma mansoni bromodomain containing protein 0.0071 0.0674 0.0674
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0612 0.0879
Echinococcus multilocularis neuropeptide s receptor 0.0507 0.6625 0.6625
Toxoplasma gondii hypothetical protein 0.0053 0.0433 0.6629
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0243 0.0547
Echinococcus granulosus tar DNA binding protein 0.0069 0.0651 0.0651
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0039 0.0245 0.0553
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0026 0.0067 0.0067
Echinococcus multilocularis importin subunit beta 1 0.0029 0.0095 0.0095
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0651 0.0651
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0245 0.0553
Schistosoma mansoni hypothetical protein 0.0304 0.3864 0.3864
Echinococcus granulosus importin subunit beta 1 0.0029 0.0095 0.0095
Onchocerca volvulus 0.0039 0.0243 0.2186
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0243 0.0528
Loa Loa (eye worm) WD domain-containing protein 0.0027 0.0068 0.0176
Echinococcus granulosus lysosomal alpha glucosidase 0.0178 0.2136 0.2136
Echinococcus granulosus jumonji domain containing 1A 0.0027 0.008 0.008
Loa Loa (eye worm) PHD-finger family protein 0.0032 0.0141 0.0364
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0098 0.1045 0.3641
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0032 0.0141 0.0141
Loa Loa (eye worm) jmjC domain-containing protein 0.0066 0.0604 0.1563
Loa Loa (eye worm) hypothetical protein 0.0039 0.0243 0.0629
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0039 0.0242 0.0242
Echinococcus granulosus neuropeptide s receptor 0.0507 0.6625 0.6625
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0243 0.0847
Toxoplasma gondii ABC1 family protein 0.0039 0.0243 0.3062
Entamoeba histolytica hypothetical protein 0.0036 0.0192 0.0421
Schistosoma mansoni alpha-glucosidase 0.0153 0.1798 0.1798
Trypanosoma brucei mitochondrial DNA polymerase beta 0.033 0.4211 1
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0346 0.4438 1
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0027 0.008 0.003
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.0192 0.0192
Echinococcus granulosus peregrin 0.0034 0.0176 0.0176
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0057 0.0478 0.1089
Schistosoma mansoni alpha glucosidase 0.0039 0.0245 0.0245
Trichomonas vaginalis D-aminoacylase, putative 0.0039 0.0243 0.0547
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0066 0.0612 0.1408
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0612 0.0879
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0067 0.0615 0.0615
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0031 0.0133 0.0133
Loa Loa (eye worm) hypothetical protein 0.0163 0.1934 0.5006
Echinococcus multilocularis neutral alpha glucosidase AB 0.0039 0.0245 0.0245
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0039 0.0245 0.0553
Brugia malayi jmjC domain containing protein 0.0027 0.008 0.028
Loa Loa (eye worm) hypothetical protein 0.0027 0.0068 0.0176
Echinococcus multilocularis phd:f box containing protein 0.0027 0.008 0.008
Treponema pallidum fructose-bisphosphate aldolase 0.0319 0.4066 0.5
Echinococcus granulosus intestinal type alkaline phosphatase 1 0.0178 0.2132 0.2132
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0339 0.0758
Echinococcus multilocularis intestinal type alkaline phosphatase 0.0178 0.2132 0.2132
Schistosoma mansoni alpha-glucosidase 0.0153 0.1798 0.1798
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0245 0.0553
Toxoplasma gondii histone lysine methyltransferase SET1 0.0062 0.0553 0.8893
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.4066 1
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0066 0.0612 0.0612
Trichomonas vaginalis esterase, putative 0.0039 0.0243 0.0547
Leishmania major hypothetical protein, conserved 0.0027 0.008 0.014
Loa Loa (eye worm) hypothetical protein 0.0039 0.0243 0.0629
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0245 0.0533
Loa Loa (eye worm) hypothetical protein 0.0044 0.0314 0.0812
Onchocerca volvulus 0.0103 0.1112 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.4066 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0069 0.0651 0.1684
Loa Loa (eye worm) hypothetical protein 0.0072 0.0685 0.1774
Echinococcus multilocularis cpg binding protein 0.0035 0.0187 0.0187
Schistosoma mansoni cpg binding protein 0.0035 0.0187 0.0187
Brugia malayi beta-lactamase family protein 0.0039 0.0243 0.0847
Trypanosoma brucei importin beta-1 subunit, putative 0.0029 0.0095 0.0066
Loa Loa (eye worm) beta-lactamase 0.0039 0.0243 0.0629
Schistosoma mansoni alkaline phosphatase 0.0178 0.2132 0.2132
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0339 0.0758
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0067 0.0621 0.0621
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0066 0.0612 0.0612
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0098 0.1045 0.1045
Brugia malayi Bromodomain containing protein 0.0034 0.0176 0.0614
Echinococcus multilocularis peregrin 0.0034 0.0176 0.0176
Brugia malayi Importin beta-1 subunit 0.0029 0.0095 0.0332
Echinococcus granulosus phd:f box containing protein 0.0027 0.008 0.008
Brugia malayi jmjC domain containing protein 0.0027 0.008 0.028
Loa Loa (eye worm) jmjC domain-containing protein 0.0027 0.008 0.0208
Brugia malayi beta-lactamase family protein 0.0039 0.0243 0.0847
Echinococcus multilocularis jumonji domain containing protein 0.0044 0.0311 0.0311
Schistosoma mansoni zinc finger protein 0.0023 0.0022 0.0022
Mycobacterium tuberculosis Conserved hypothetical protein 0.0174 0.2079 0.4376
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0319 0.4066 1
Schistosoma mansoni tar DNA-binding protein 0.0069 0.0651 0.0651
Echinococcus granulosus arachidonate 5 lipoxygenase 0.006 0.0529 0.0529
Echinococcus multilocularis alkaline phosphatase 0.0178 0.2132 0.2132
Echinococcus multilocularis alkaline phosphatase, intestinal, gene 2 0.0178 0.2132 0.2132
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0098 0.1045 0.1045
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.006 0.0529 0.0529
Brugia malayi beta-lactamase 0.0039 0.0243 0.0847
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0156 0.1836 0.3797
Schistosoma mansoni phospholipase A-2-activating protein 0.0027 0.0068 0.0068
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0245 0.0553
Echinococcus multilocularis intestinal type alkaline phosphatase 1 0.0178 0.2132 0.2132
Trichomonas vaginalis alpha-glucosidase, putative 0.0039 0.0245 0.0553
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0156 0.1838 0.4336
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0339 0.0758
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0232 0.287 0.7427
Trichomonas vaginalis sucrase-isomaltase, putative 0.0039 0.0245 0.0553
Toxoplasma gondii PUL domain-containing protein 0.0039 0.0243 0.3071
Mycobacterium ulcerans 3-oxoacyl-ACP synthase 0.0346 0.4438 1
Schistosoma mansoni lipoxygenase 0.006 0.0529 0.0529
Brugia malayi follicle stimulating hormone receptor 0.0232 0.287 1
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0243 0.0243
Brugia malayi WD domain containing protein 0.0039 0.0243 0.0848
Echinococcus granulosus PHD finger protein rhinoceros 0.0032 0.0141 0.0141
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0243 0.0629
Echinococcus multilocularis neuropeptide receptor A26 0.0507 0.6625 0.6625
Loa Loa (eye worm) jmjC domain-containing protein 0.0107 0.1163 0.3009
Trichomonas vaginalis maltase-glucoamylase, putative 0.0039 0.0245 0.0553

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

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