Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | muscleblind protein 1 | 0.03 | 1 | 1 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0096 | 0.2667 | 0.1387 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2667 | 1 |
Brugia malayi | hypothetical protein | 0.0024 | 0.009 | 0.009 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0096 | 0.2667 | 1 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.009 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0126 | 0.3733 | 0.2638 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0096 | 0.2667 | 0.3686 |
Schistosoma mansoni | eyes absent homolog | 0.0177 | 0.5576 | 1 |
Brugia malayi | RNA binding protein | 0.0126 | 0.3733 | 0.3733 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2667 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.3733 | 0.5998 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2667 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.03 | 1 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0096 | 0.2667 | 0.1387 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.0063 | 0.1486 | 1 |
Loa Loa (eye worm) | RNA binding protein | 0.0126 | 0.3733 | 0.3733 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0096 | 0.2667 | 0.2667 |
Loa Loa (eye worm) | hypothetical protein | 0.0024 | 0.009 | 0.009 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.0063 | 0.1486 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0126 | 0.3733 | 0.3733 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2667 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0024 | 0.009 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.3733 | 0.5998 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0096 | 0.2667 | 1 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0096 | 0.2667 | 0.5 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2667 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.3733 | 0.5998 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0024 | 0.009 | 0.5 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.1486 | 0.5 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0096 | 0.2667 | 0.5 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0096 | 0.2667 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.3733 | 0.5998 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.0063 | 0.1486 | 0.5418 |
Trypanosoma brucei | polo-like protein kinase | 0.0096 | 0.2667 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0126 | 0.3733 | 0.2638 |
Brugia malayi | hypothetical protein | 0.0177 | 0.5576 | 0.5576 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.1486 | 0.1123 |
Giardia lamblia | Kinase, PLK | 0.0096 | 0.2667 | 0.5 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.0063 | 0.1486 | 0.1123 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.1486 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0126 | 0.3733 | 0.5998 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.0063 | 0.1486 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0126 | 0.3733 | 0.3733 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0126 | 0.3733 | 0.3733 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.5576 | 0.5576 |
Echinococcus multilocularis | muscleblind protein | 0.03 | 1 | 1 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0126 | 0.3733 | 0.3733 |
Loa Loa (eye worm) | hypothetical protein | 0.03 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0177 | 0.5576 | 0.5576 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0096 | 0.2667 | 0.2667 |
Echinococcus granulosus | muscleblind protein | 0.03 | 1 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2667 | 1 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0096 | 0.2667 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.