Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.1018 | 0.1018 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0214 | 0.0098 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.1018 | 0.1018 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.1018 | 0.0911 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0398 | 0.5 |
Echinococcus granulosus | FTZ F1 alpha | 0.001 | 0.1018 | 0.0911 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0795 | 0.0685 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0398 | 0.5 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.1018 | 0.0911 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0503 | 0.039 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0118 | 0.0118 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.001 | 0.1018 | 0.0911 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0005 | 0.0214 | 0.0214 |
Schistosoma mansoni | hypothetical protein | 0.0013 | 0.1551 | 0.1551 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0398 | 0.5 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4374 | 0.4374 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.001 | 0.1018 | 0.0911 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.001 | 0.1018 | 0.0911 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0005 | 0.0118 | 0.0118 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.1018 | 0.0911 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0029 | 0.4302 | 0.5 |
Brugia malayi | nuclear hormone receptor | 0.001 | 0.1018 | 0.0911 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.1018 | 0.1018 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1018 | 0.0911 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0029 | 0.4302 | 0.5 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 1 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.001 | 0.1018 | 0.0911 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.1018 | 0.1018 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0398 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1018 | 0.0911 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.4302 | 0.5 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0398 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1018 | 0.0911 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.4101 | 0.4031 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0398 | 0.5 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0029 | 0.4302 | 0.5 |
Brugia malayi | hypothetical protein | 0.0019 | 0.2534 | 0.2445 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.1018 | 0.0911 |
Echinococcus multilocularis | FTZ F1 alpha | 0.001 | 0.1018 | 0.0911 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.001 | 0.1018 | 0.0911 |
Brugia malayi | nuclear receptor RXR | 0.0005 | 0.0214 | 0.0098 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0118 | 0.0118 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.001 | 0.1018 | 0.0911 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.1018 | 0.1018 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 1 | 1 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.001 | 0.1018 | 0.0911 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.001 | 0.1018 | 0.0911 |
Onchocerca volvulus | Bile acid receptor homolog | 0.001 | 0.1018 | 0.2261 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1018 | 0.0911 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.1018 | 0.0911 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0214 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0214 | 0.0098 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 1 | 1 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.001 | 0.1018 | 0.0911 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.1018 | 0.1018 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0398 | 0.5 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.001 | 0.1018 | 0.2261 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.1018 | 0.1018 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.001 | 0.1018 | 0.0911 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.4302 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.1018 | 0.0911 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.001 | 0.1018 | 0.0911 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0005 | 0.0118 | 0.0118 |
Loa Loa (eye worm) | steroid hormone receptor | 0.001 | 0.1018 | 0.0911 |
Onchocerca volvulus | 0.0028 | 0.4101 | 1 | |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0398 | 0.5 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.1018 | 0.1018 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.1018 | 0.1018 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0006 | 0.0398 | 0.5 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.001 | 0.1018 | 0.0911 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0398 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.001 | 0.1018 | 0.0911 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.001 | 0.1018 | 0.0911 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0053 | 0.8384 | 1 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0214 | 0.0098 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0005 | 0.0214 | 0.0098 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1018 | 0.0911 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0503 | 0.039 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.001 | 0.1018 | 0.0911 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0398 | 0.5 |
Brugia malayi | TAR-binding protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.1018 | 0.1018 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0398 | 0.5 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0005 | 0.0214 | 0.0098 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Brugia malayi | ecdysteroid receptor | 0.001 | 0.1018 | 0.0911 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0398 | 0.5 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0795 | 0.0685 |
Loa Loa (eye worm) | hypothetical protein | 0.0029 | 0.4302 | 0.4234 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0398 | 0.5 |
Schistosoma mansoni | nuclear receptor | 0.0005 | 0.0118 | 0.0118 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.001 | 0.1018 | 0.0911 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0398 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.001 | 0.1018 | 0.0911 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.001 | 0.1018 | 0.0911 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1018 | 0.0911 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.1018 | 0.1018 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.4374 | 0.4374 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.4101 | 0.4101 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0029 | 0.4302 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0214 | 0.0098 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.001 | 0.1018 | 0.0911 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 1 | 1 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0795 | 0.0685 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0005 | 0.0214 | 0.0098 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.001 | 0.1018 | 0.2261 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.1018 | 0.1018 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0214 | 0.0098 |
Leishmania major | hypothetical protein, conserved | 0.0029 | 0.4302 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.001 | 0.1018 | 0.0911 |
Brugia malayi | hypothetical protein | 0.0005 | 0.0214 | 0.0098 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.001 | 0.1018 | 0.0911 |
Schistosoma mansoni | nuclear hormone receptor | 0.0005 | 0.0118 | 0.0118 |
Brugia malayi | hypothetical protein | 0.0029 | 0.4302 | 0.4234 |
Brugia malayi | nuclear receptor NHR-88 | 0.001 | 0.1018 | 0.0911 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.1018 | 0.0911 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1018 | 0.0911 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 1 | 1 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0503 | 0.039 |
Brugia malayi | steroid hormone receptor | 0.001 | 0.1018 | 0.0911 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.0776 | 0.0666 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.001 | 0.1018 | 0.0911 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0005 | 0.0118 | 0.0118 |
Loa Loa (eye worm) | hypothetical protein | 0.0005 | 0.0214 | 0.0098 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.4374 | 0.4307 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.001 | 0.1018 | 0.0911 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.001 | 0.1018 | 0.0911 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.4374 | 0.4307 |
Loa Loa (eye worm) | hypothetical protein | 0.001 | 0.1018 | 0.0911 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 1 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0006 | 0.0398 | 0.5 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.001 | 0.1018 | 0.0911 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.001 | 0.1018 | 0.0911 |
Onchocerca volvulus | 0.001 | 0.1018 | 0.2261 | |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0503 | 0.039 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.001 | 0.1018 | 0.0911 |
Echinococcus granulosus | Ataxin 2 N terminaldomain containing protein | 0.0013 | 0.1551 | 0.145 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0006 | 0.0398 | 0.5 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.001 | 0.1018 | 0.0911 |
Trichomonas vaginalis | helicase, putative | 0.0006 | 0.0398 | 0.5 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.001 | 0.1018 | 0.0911 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.001 | 0.1018 | 0.0911 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0059 | 0.9469 | 0.9469 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0503 | 0.0503 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 1 | 1 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.4101 | 0.4031 |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0005 | 0.0214 | 0.0214 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.1018 | 0.1018 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.001 | 0.1018 | 0.0911 |
Schistosoma mansoni | zinc finger protein | 0.0005 | 0.0118 | 0.0118 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.001 | 0.1018 | 0.0911 |
Echinococcus multilocularis | Ataxin 2, N terminal,domain containing protein | 0.0013 | 0.1551 | 0.145 |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0005 | 0.0214 | 0.0098 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.