Detailed information for compound 796004

Basic information

Technical information
  • TDR Targets ID: 796004
  • Name: N-[(2-ethoxyphenyl)methylideneamino]-2-methyl quinoline-4-carboxamide
  • MW: 333.384 | Formula: C20H19N3O2
  • H donors: 1 H acceptors: 2 LogP: 3.84 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOc1ccccc1C=NNC(=O)c1cc(C)nc2c1cccc2
  • InChi: 1S/C20H19N3O2/c1-3-25-19-11-7-4-8-15(19)13-21-23-20(24)17-12-14(2)22-18-10-6-5-9-16(17)18/h4-13H,3H2,1-2H3,(H,23,24)/b21-13+
  • InChiKey: NXDPDQVFOYLPEI-FYJGNVAPSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-[(2-ethoxyphenyl)methyleneamino]-2-methyl-quinoline-4-carboxamide
  • N-[(2-ethoxyphenyl)methyleneamino]-2-methyl-4-quinolinecarboxamide
  • N-[(2-ethoxybenzylidene)amino]-2-methyl-cinchoninamide
  • N-[(2-ethoxyphenyl)methylideneamino]-2-methyl-quinoline-4-carboxamide
  • A0584/0026950

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Onchocerca volvulus 0.0189 0.0432 1
Leishmania major mitochondrial DNA polymerase beta 0.0326 0.079 1
Loa Loa (eye worm) hypothetical protein 0.1936 0.4997 0.9944
Brugia malayi nuclear receptor NHR-88 0.0089 0.0171 0.0299
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0054 0.0079 0.0124
Echinococcus multilocularis FTZ F1 alpha 0.0189 0.0432 0.0432
Schistosoma mansoni microtubule-associated protein tau 0.3852 1 1
Brugia malayi Nuclear hormone receptor E75 0.0089 0.0171 0.0299
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0189 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0311
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0189 0.0432 0.0796
Loa Loa (eye worm) hypothetical protein 0.01 0.0199 0.0366
Brugia malayi orphan nuclear receptor NR2E1 0.0089 0.0171 0.0299
Brugia malayi nuclear hormone receptor family member odr-7 0.0089 0.0171 0.0299
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.005 0.045
Loa Loa (eye worm) hypothetical protein 0.01 0.0199 0.0366
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0189 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.01 0.0199 0.0366
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0189 0.0432 0.0432
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.01 0.0199 0.0199
Echinococcus multilocularis tumor protein p63 0.0762 0.1927 0.1927
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0189 0.0432 0.0796
Echinococcus multilocularis nuclear receptor nhr 48 0.0089 0.0171 0.0171
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0089 0.0171 0.2595
Echinococcus granulosus geminin 0.0381 0.0933 0.0933
Schistosoma mansoni nuclear hormone receptor 0.0089 0.0171 0.0171
Trichomonas vaginalis DNA polymerase eta, putative 0.0043 0.005 0.5
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0189 0.0432 0.0432
Brugia malayi nuclear receptor NHR-88 0.0189 0.0432 0.0796
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0311
Echinococcus granulosus survival motor neuron protein 1 0.0266 0.0632 0.0632
Brugia malayi hypothetical protein 0.0266 0.0632 0.1178
Trypanosoma brucei unspecified product 0.0043 0.005 0.045
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.01 0.0199 0.0199
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0189 0.0432 1
Trypanosoma cruzi DNA polymerase eta, putative 0.007 0.0121 0.0957
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.005 0.045
Loa Loa (eye worm) nuclear receptor NHR-67 0.0089 0.0171 0.0311
Schistosoma mansoni nuclear receptor nhr-48 0.0089 0.0171 0.0171
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0154 0.0341 0.3933
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0189 0.0432 0.0432
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.005 0.045
Toxoplasma gondii histone lysine methyltransferase SET1 0.0181 0.0412 0.8621
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0326 0.079 1
Brugia malayi MH2 domain containing protein 0.0137 0.0294 0.0534
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0189 0.0432 0.0832
Brugia malayi ImpB/MucB/SamB family protein 0.01 0.0198 0.0351
Schistosoma mansoni nuclear hormone receptor 0.0089 0.0171 0.0171
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.1097 0.2803 0.2803
Schistosoma mansoni cpg binding protein 0.0101 0.0202 0.0202
Loa Loa (eye worm) hypothetical protein 0.0189 0.0432 0.0832
Echinococcus granulosus Nuclear hormone receptor HR96 0.0089 0.0171 0.0171
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0202 0.0466 1
Echinococcus granulosus FTZ F1 alpha 0.0189 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0189 0.0432 0.0832
Schistosoma mansoni thyroid hormone receptor 0.1286 0.3297 0.3297
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0311
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0189 0.0432 0.0432
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0189 0.0432 0.0832
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0058 0.0102
Brugia malayi photoreceptor-specific nuclear receptor 0.0189 0.0432 0.0796
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0189 0.0432 0.0432
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0189 0.0432 0.0432
Schistosoma mansoni coup transcription factor 0.0189 0.0432 0.0432
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.005 0.045
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0189 0.0432 0.0832
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0189 0.0432 0.0796
Echinococcus multilocularis dna polymerase kappa 0.0043 0.005 0.005
Giardia lamblia DINP protein human, muc B family 0.0043 0.005 0.5
Brugia malayi nuclear hormone receptor 0.0189 0.0432 0.0796
Schistosoma mansoni nuclear receptor 0.0089 0.0171 0.0171
Schistosoma mansoni thyroid hormone receptor 0.1286 0.3297 0.3297
Brugia malayi Nuclear hormone receptor-like 1 0.1947 0.5025 0.9556
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0189 0.0432 0.0432
Echinococcus granulosus dna polymerase eta 0.01 0.0198 0.0198
Trypanosoma cruzi DNA polymerase eta, putative 0.01 0.0198 0.2004
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0103 0.0206 0.0206
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0202 0.0466 0.0466
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0189 0.0432 0.0796
Echinococcus multilocularis thyroid hormone receptor alpha 0.1286 0.3297 0.3297
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0189 0.0432 0.0432
Brugia malayi nuclear receptor RXR 0.0089 0.0171 0.0299
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0311
Trypanosoma brucei DNA polymerase eta, putative 0.01 0.0198 0.2364
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0089 0.0171 0.0171
Brugia malayi hypothetical protein 0.0089 0.0171 0.0299
Brugia malayi Steroid receptor seven-up type 2 0.0189 0.0432 0.0796
Schistosoma mansoni cellular tumor antigen P53 0.0111 0.0229 0.0229
Onchocerca volvulus 0.0089 0.0171 0.2595
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0189 0.0432 0.0432
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0189 0.0432 0.0796
Leishmania major DNA polymerase eta, putative 0.007 0.0121 0.0957
Schistosoma mansoni retinoid-x-receptor (RXR) 0.01 0.0199 0.0199
Loa Loa (eye worm) hypothetical protein 0.01 0.0199 0.0366
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.005 0.045
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.003 0.0015 0.0015
Brugia malayi Muscleblind-like protein 0.0171 0.0384 0.0705
Onchocerca volvulus 0.0089 0.0171 0.2595
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0189 0.0432 0.0796
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0089 0.0171 0.0311
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0189 0.0432 0.0832
Loa Loa (eye worm) hypothetical protein 0.0189 0.0432 0.0832
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0103 0.0206 0.0206
Brugia malayi hypothetical protein 0.01 0.0199 0.0352
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0189 0.0432 0.0432
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.005 0.045
Schistosoma mansoni aldehyde dehydrogenase 0.0202 0.0466 0.0466
Schistosoma mansoni hypothetical protein 0.0054 0.0079 0.0079
Brugia malayi steroid hormone receptor 0.0189 0.0432 0.0796
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0189 0.0432 0.0432
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0189 0.0432 0.0796
Brugia malayi nuclear receptor RXR 0.01 0.0199 0.0352
Onchocerca volvulus Bile acid receptor homolog 0.0189 0.0432 1
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0311
Brugia malayi Nuclear hormone receptor E75 0.0089 0.0171 0.0299
Schistosoma mansoni RAR-like nuclear receptor 0.0189 0.0432 0.0432
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.005 0.045
Loa Loa (eye worm) hypothetical protein 0.0266 0.0632 0.1231
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0089 0.0171 0.0299
Onchocerca volvulus 0.0096 0.0188 0.3082
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0326 0.079 1
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0046 0.0058 0.0547
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0203 0.0469 0.0469
Schistosoma mansoni hypothetical protein 0.1097 0.2803 0.2803
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0189 0.0432 0.0796
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.005 0.045
Brugia malayi CXXC zinc finger family protein 0.0096 0.0188 0.0331
Echinococcus granulosus ecdysone induced protein 78C 0.0189 0.0432 0.0432
Echinococcus granulosus Nuclear hormone receptor HR96 0.0089 0.0171 0.0171
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0089 0.0171 0.0171
Echinococcus granulosus tumor protein p63 0.0762 0.1927 0.1927
Loa Loa (eye worm) hypothetical protein 0.01 0.0198 0.0365
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0189 0.0432 0.0432
Brugia malayi nuclear hormone receptor 0.0089 0.0171 0.0299
Brugia malayi tailless protein 0.0089 0.0171 0.0299
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0189 0.0432 0.0432
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0043 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0189 0.0432 0.0832
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0046 0.0058 0.0102
Loa Loa (eye worm) hypothetical protein 0.0189 0.0432 0.0832
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.1947 0.5025 1
Leishmania major DNA polymerase eta, putative 0.01 0.0198 0.2004
Brugia malayi hypothetical protein 0.0089 0.0171 0.0299
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0189 0.0432 0.0796
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.003 0.0015 0.0015
Brugia malayi ecdysteroid receptor 0.0189 0.0432 0.0796
Loa Loa (eye worm) hypothetical protein 0.0171 0.0384 0.0736
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0089 0.0171 0.2595
Schistosoma mansoni zinc finger protein 0.0089 0.0171 0.0171
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0311
Echinococcus multilocularis dna polymerase eta 0.01 0.0198 0.0198
Echinococcus granulosus nuclear receptor nhr 48 0.0089 0.0171 0.0171
Mycobacterium ulcerans aldehyde dehydrogenase 0.0202 0.0466 1
Loa Loa (eye worm) hypothetical protein 0.0171 0.0384 0.0736
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0056 0.0084 0.0456
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0311
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0043 0.005 0.5
Schistosoma mansoni aldehyde dehydrogenase 0.0202 0.0466 0.0466
Brugia malayi Nuclear hormone receptor-like 1 0.1947 0.5025 0.9556
Schistosoma mansoni hypothetical protein 0.0381 0.0933 0.0933
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.1097 0.2803 0.2803
Toxoplasma gondii aldehyde dehydrogenase 0.0202 0.0466 1
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0189 0.0432 0.0432
Loa Loa (eye worm) CXXC zinc finger family protein 0.0096 0.0188 0.0345
Brugia malayi nuclear hormone receptor family member nhr-6 0.0089 0.0171 0.0299
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0103 0.0206 0.0206
Toxoplasma gondii ImpB/MucB/SamB family protein 0.007 0.0121 0.1169
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0189 0.0432 0.0432
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0189 0.0432 0.0832
Loa Loa (eye worm) steroid hormone receptor 0.0189 0.0432 0.0832
Loa Loa (eye worm) hypothetical protein 0.0189 0.0432 0.0832
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0103 0.0206 0.0382
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0189 0.0432 0.0432
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0103 0.0206 0.0367
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0103 0.0206 0.0206
Onchocerca volvulus 0.0111 0.0229 0.4245
Loa Loa (eye worm) hypothetical protein 0.01 0.0199 0.0366
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0202 0.0466 0.0466
Schistosoma mansoni nuclear hormone receptor 0.0189 0.0432 0.0432
Brugia malayi nuclear receptor NHR-67 0.0089 0.0171 0.0299
Echinococcus multilocularis geminin 0.0381 0.0933 0.0933
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0311
Loa Loa (eye worm) DR-78 0.0089 0.0171 0.0311
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0089 0.0171 0.0171
Loa Loa (eye worm) nuclear hormone receptor 0.0089 0.0171 0.0311
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0189 0.0432 0.0796
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0189 0.0432 0.0796
Onchocerca volvulus Protein ultraspiracle homolog 0.0189 0.0432 1
Echinococcus multilocularis ecdysone induced protein 78C 0.0189 0.0432 0.0432
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0089 0.0171 0.0171
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0103 0.0206 0.0206
Brugia malayi Nuclear hormone receptor-like 1 0.2036 0.5258 1
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0311
Brugia malayi hypothetical protein 0.01 0.0199 0.0352
Loa Loa (eye worm) hypothetical protein 0.0189 0.0432 0.0832
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0089 0.0171 0.0171
Schistosoma mansoni terminal deoxycytidyl transferase 0.0043 0.005 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0189 0.0432 0.0832
Schistosoma mansoni survival motor neuron protein 0.0054 0.0079 0.0079
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0189 0.0432 0.0796
Echinococcus multilocularis survival motor neuron protein 1 0.0266 0.0632 0.0632
Echinococcus granulosus thyroid hormone receptor alpha 0.0089 0.0171 0.0171
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0189 0.0432 0.0796
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.005 0.045
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0089 0.0171 0.0171
Echinococcus granulosus muscleblind protein 0.0171 0.0384 0.0384
Mycobacterium ulcerans aldehyde dehydrogenase 0.0202 0.0466 1
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0089 0.0171 0.0171
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.005 0.045
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.005 0.045
Echinococcus multilocularis muscleblind protein 1 0.0171 0.0384 0.0384
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0154 0.0341 0.3933
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0311
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.01 0.0199 0.0199
Brugia malayi conserved hypotetical protein 0.0089 0.0171 0.0299
Schistosoma mansoni cpg binding protein 0.0101 0.0202 0.0202
Echinococcus multilocularis cpg binding protein 0.0101 0.0202 0.0202
Brugia malayi ImpB/MucB/SamB family protein 0.0043 0.005 0.0068
Echinococcus granulosus cpg binding protein 0.0101 0.0202 0.0202
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0189 0.0432 0.0432
Loa Loa (eye worm) hypothetical protein 0.0189 0.0432 0.0832
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0311
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0189 0.0432 0.0832
Schistosoma mansoni cpg binding protein 0.0096 0.0188 0.0188
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0202 0.0466 0.562
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0103 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0089 0.0171 0.0311
Schistosoma mansoni steroid hormone receptor ad4bp 0.0189 0.0432 0.0432
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0046 0.0058 0.0102
Loa Loa (eye worm) MH2 domain-containing protein 0.0137 0.0294 0.0557
Mycobacterium ulcerans hypothetical protein 0.0172 0.0387 0.8094
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0326 0.079 1
Brugia malayi ecdysone receptor 0.0089 0.0171 0.0299
Echinococcus granulosus dna polymerase kappa 0.0043 0.005 0.005
Schistosoma mansoni nuclear receptor 0.0089 0.0171 0.0171
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0103 0.0206 0.0206
Loa Loa (eye worm) transcription factor SMAD2 0.0137 0.0294 0.0557
Mycobacterium tuberculosis Conserved hypothetical protein 0.0172 0.0387 0.8094
Schistosoma mansoni retinoic acid receptor RXR 0.0189 0.0432 0.0432
Trypanosoma brucei DNA polymerase IV, putative 0.0043 0.005 0.045
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0089 0.0171 0.0171
Echinococcus multilocularis muscleblind protein 0.0171 0.0384 0.0384
Trypanosoma brucei DNA polymerase kappa, putative 0.0043 0.005 0.045
Schistosoma mansoni DNA polymerase eta 0.01 0.0198 0.0198
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0043 0.005 0.005
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0089 0.0171 0.0171
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0154 0.0341 0.4206
Entamoeba histolytica deoxycytidyl transferase, putative 0.0043 0.005 0.5
Echinococcus multilocularis microtubule associated protein 2 0.3852 1 1
Loa Loa (eye worm) hypothetical protein 0.0111 0.0229 0.0427
Mycobacterium ulcerans aldehyde dehydrogenase 0.0202 0.0466 1
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0043 0.005 0.005
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0043 0.005 0.007
Schistosoma mansoni hypothetical protein 0.0381 0.0933 0.0933

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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