Detailed information for compound 797333

Basic information

Technical information
  • TDR Targets ID: 797333
  • Name: 4-bromo-N-[5-(4-fluorophenyl)-1,3,4-thiadiazo l-2-yl]benzamide
  • MW: 378.219 | Formula: C15H9BrFN3OS
  • H donors: 1 H acceptors: 3 LogP: 3.99 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: Fc1ccc(cc1)c1nnc(s1)NC(=O)c1ccc(cc1)Br
  • InChi: 1S/C15H9BrFN3OS/c16-11-5-1-9(2-6-11)13(21)18-15-20-19-14(22-15)10-3-7-12(17)8-4-10/h1-8H,(H,18,20,21)
  • InChiKey: FSURHSKCGICHQY-UHFFFAOYSA-N  

Network

Hover on a compound node to display the structore

Synonyms

  • Oprea1_256811
  • Oprea1_382222
  • 4-Bromo-N-[5-(4-fluoro-phenyl)-[1,3,4]thiadiazol-2-yl]-benzamide
  • BAS 00704373
  • A2191/0092155
  • ZINC02273941

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity

Obtained from network model

Ranking Plot


Putative Targets List


Species Potential target Raw Global Species
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0033 0.0003 0.0003
Trypanosoma brucei hypothetical protein, conserved 0.0039 0.0016 0.0264
Brugia malayi acetyltransferase, GNAT family protein 0.0166 0.0271 0.0271
Echinococcus multilocularis survival motor neuron protein 1 0.0261 0.0459 0.0459
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0049 0.0036 0.0152
Loa Loa (eye worm) hypothetical protein 0.0851 0.1638 0.1638
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0041 0.0019 0.0019
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0036 0.0152
Loa Loa (eye worm) hypothetical protein 0.006 0.0058 0.0058
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.007 0.0077 0.0077
Echinococcus multilocularis geminin 0.0152 0.0242 0.0242
Echinococcus granulosus histone acetyltransferase KAT2B 0.0162 0.0261 0.0261
Loa Loa (eye worm) D-ets-4 DNA binding domain-containing protein 0.007 0.0078 0.0078
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0226 0.039 0.039
Echinococcus multilocularis para nitrobenzyl esterase 0.0851 0.1638 0.1638
Chlamydia trachomatis glutamine binding protein 0.0069 0.0075 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0016 0.0016
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0036 0.0036
Schistosoma mansoni BC026374 protein (S09 family) 0.0851 0.1638 0.1638
Schistosoma mansoni hypothetical protein 0.0114 0.0165 0.0165
Schistosoma mansoni glutamate receptor NMDA 0.0226 0.039 0.039
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0077 0.0077
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0039 0.0016 0.0056
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0016
Schistosoma mansoni ets-related 0.0212 0.0362 0.0362
Echinococcus granulosus neuroligin 0.0851 0.1638 0.1638
Brugia malayi Carboxylesterase family protein 0.5037 1 1
Mycobacterium ulcerans beta-lactamase 0.0039 0.0016 0.0031
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0016 0.0264
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.007 0.0077 0.043
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0036 0.0609
Loa Loa (eye worm) hypothetical protein 0.0033 0.0003 0.0003
Mycobacterium tuberculosis Probable hydrolase 0.0039 0.0016 0.0056
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0033 0.0003 0.0003
Echinococcus multilocularis carboxylesterase 5A 0.5037 1 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0041 0.0019 0.0019
Plasmodium vivax hypothetical protein, conserved 0.0039 0.0016 0.2059
Onchocerca volvulus 0.0851 0.1638 1
Toxoplasma gondii aldehyde dehydrogenase 0.007 0.0077 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0077 0.0406
Loa Loa (eye worm) hypothetical protein 0.0037 0.0011 0.0011
Brugia malayi Carboxylesterase family protein 0.0851 0.1638 0.1638
Schistosoma mansoni hypothetical protein 0.0033 0.0003 0.0003
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0851 0.1638 1
Entamoeba histolytica hypothetical protein 0.0114 0.0165 1
Schistosoma mansoni gliotactin 0.0851 0.1638 0.1638
Loa Loa (eye worm) latrophilin receptor protein 2 0.0033 0.0003 0.0003
Brugia malayi hypothetical protein 0.0261 0.0459 0.0459
Loa Loa (eye worm) cytochrome P450 family protein 0.0056 0.005 0.005
Echinococcus granulosus geminin 0.0152 0.0242 0.0242
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0036 0.0491
Loa Loa (eye worm) hypothetical protein 0.0049 0.0036 0.0036
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0041 0.0019 0.0019
Mycobacterium tuberculosis Conserved protein 0.0039 0.0016 0.0056
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0033 0.0003 0.0003
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0036 0.0491
Brugia malayi Carboxylesterase family protein 0.0851 0.1638 0.1638
Schistosoma mansoni cellular tumor antigen P53 0.0104 0.0146 0.0146
Echinococcus multilocularis glutamate receptor 2 0.0041 0.0019 0.0019
Giardia lamblia Histone acetyltransferase GCN5 0.0045 0.0028 0.5
Loa Loa (eye worm) carboxylesterase 0.5037 1 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0077 0.0406
Brugia malayi Latrophilin receptor protein 2 0.0033 0.0003 0.0003
Loa Loa (eye worm) hypothetical protein 0.0104 0.0146 0.0146
Entamoeba histolytica hypothetical protein 0.0114 0.0165 1
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0039 0.0016 0.0016
Echinococcus multilocularis GA binding protein alpha chain 0.007 0.0078 0.0078
Loa Loa (eye worm) acetylcholinesterase 1 0.5037 1 1
Echinococcus multilocularis microtubule associated protein 2 0.0751 0.1439 0.1439
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0053 0.0044 0.0044
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0069 0.0075 1
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0011 0.0025
Mycobacterium tuberculosis Possible penicillin-binding protein 0.025 0.0438 0.2642
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0049 0.0036 0.0176
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0114 0.0165 0.3871
Loa Loa (eye worm) hypothetical protein 0.0037 0.0011 0.0011
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0069 0.0075 0.5
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0039 0.0016 0.0056
Loa Loa (eye worm) hypothetical protein 0.5037 1 1
Loa Loa (eye worm) hypothetical protein 0.0851 0.1638 0.1638
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0114 0.0165 0.3871
Onchocerca volvulus 0.0851 0.1638 1
Trichomonas vaginalis carboxylesterase domain containing protein, putative 0.0851 0.1638 1
Brugia malayi latrophilin 2 splice variant baaae 0.0071 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0261 0.0459 0.0459
Schistosoma mansoni hypothetical protein 0.0033 0.0003 0.0003
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0049 0.0036 0.3301
Onchocerca volvulus 0.0039 0.0016 0.01
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0069 0.0075 0.0417
Mycobacterium tuberculosis Conserved protein 0.0039 0.0016 0.0056
Mycobacterium tuberculosis Probable lipase LipD 0.0039 0.0016 0.0056
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0016
Mycobacterium tuberculosis Probable esterase LipL 0.0039 0.0016 0.0056
Entamoeba histolytica acyl-coA synthetase, putative 0.0049 0.0036 0.0609
Echinococcus granulosus tumor protein p63 0.0711 0.1359 0.1359
Brugia malayi beta-lactamase 0.0039 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0037 0.0011 0.0011
Leishmania major 4-coumarate:coa ligase-like protein 0.0049 0.0036 0.0491
Loa Loa (eye worm) hypothetical protein 0.0851 0.1638 0.1638
Loa Loa (eye worm) hypothetical protein 0.0851 0.1638 0.1638
Onchocerca volvulus 0.0039 0.0016 0.01
Brugia malayi beta-lactamase family protein 0.0039 0.0016 0.0016
Echinococcus granulosus acetylcholinesterase 0.5037 1 1
Loa Loa (eye worm) hypothetical protein 0.0071 0.0079 0.0079
Echinococcus multilocularis neuroligin 0.0851 0.1638 0.1638
Loa Loa (eye worm) hypothetical protein 0.0049 0.0036 0.0036
Echinococcus multilocularis beta LACTamase domain containing family member 0.0039 0.0016 0.0016
Echinococcus granulosus BC026374 protein S09 family 0.0851 0.1638 0.1638
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0041 0.0019 0.0019
Brugia malayi hypothetical protein 0.0114 0.0165 0.0165
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0036 1
Echinococcus granulosus survival motor neuron protein 1 0.0261 0.0459 0.0459
Echinococcus granulosus carboxylesterase 5A 0.5037 1 1
Schistosoma mansoni transcription factor LCR-F1 0.0114 0.0165 0.0165
Schistosoma mansoni hypothetical protein 0.0071 0.0079 0.0079
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0016
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0049 0.0036 0.012
Schistosoma mansoni hypothetical protein 0.0033 0.0003 0.0003
Onchocerca volvulus 0.0104 0.0146 0.0892
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0041 0.0019 0.0019
Mycobacterium ulcerans esterase/lipase LipP 0.0039 0.0016 0.0031
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0049 0.0036 0.0152
Echinococcus granulosus nmda type glutamate receptor 0.0095 0.0129 0.0129
Mycobacterium ulcerans hypothetical protein 0.0039 0.0016 0.0031
Brugia malayi Carboxylesterase family protein 0.0851 0.1638 0.1638
Brugia malayi Cytochrome P450 family protein 0.0056 0.005 0.005
Echinococcus granulosus beta LACTamase domain containing family member 0.0039 0.0016 0.0016
Loa Loa (eye worm) beta-lactamase 0.0039 0.0016 0.0016
Echinococcus multilocularis acetylcholinesterase 0.5037 1 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0041 0.0019 0.0019
Entamoeba histolytica acyl-CoA synthetase, putative 0.0049 0.0036 0.0609
Mycobacterium ulcerans hypothetical protein 0.0049 0.0036 0.0152
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0016
Loa Loa (eye worm) hypothetical protein 0.0037 0.0011 0.0011
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.5037 1 1
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0166 0.0271 0.0271
Loa Loa (eye worm) acetyltransferase 0.0166 0.0271 0.0271
Onchocerca volvulus 0.0049 0.0036 0.0221
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0166 0.0271 0.0271
Schistosoma mansoni neuroligin 3 (S09 family) 0.0851 0.1638 0.1638
Plasmodium falciparum histone acetyltransferase GCN5 0.0045 0.0028 1
Loa Loa (eye worm) carboxylesterase 0.0851 0.1638 0.1638
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0069 0.0075 0.0393
Onchocerca volvulus 0.0851 0.1638 1
Brugia malayi Fli-1 protein 0.0212 0.0362 0.0362
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0041 0.0019 0.0019
Echinococcus granulosus histone acetyltransferase KAT2B 0.0049 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0037 0.0011 0.0011
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.024 0.0418 1
Echinococcus multilocularis tumor protein p63 0.0711 0.1359 0.1359
Schistosoma mansoni lipoxygenase 0.0063 0.0065 0.0065
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0103 0.0144 0.0144
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0036 0.0036
Onchocerca volvulus 0.0851 0.1638 1
Echinococcus granulosus acetylcholinesterase 0.5037 1 1
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0039 0.0016 0.0016
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0049 0.0036 0.0152
Onchocerca volvulus 0.0039 0.0016 0.01
Echinococcus granulosus glutamate NMDA receptor subunit 0.0226 0.039 0.039
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0049 0.0036 0.0152
Mycobacterium ulcerans carboxylesterase, LipT 0.0851 0.1638 1
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0033 0.0003 0.0003
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0851 0.1638 0.1638
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0114 0.0165 0.0165
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0095 0.0129 0.0129
Echinococcus granulosus GA binding protein alpha chain 0.007 0.0078 0.0078
Brugia malayi Carboxylesterase family protein 0.0851 0.1638 0.1638
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0036 0.0152
Schistosoma mansoni hypothetical protein 0.0152 0.0242 0.0242
Trypanosoma brucei mitochondrial DNA polymerase beta 0.024 0.0418 1
Schistosoma mansoni acetylcholinesterase 0.0851 0.1638 0.1638
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.007 0.0077 0.0077
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0851 0.1638 0.1638
Brugia malayi beta-lactamase family protein 0.0039 0.0016 0.0016
Mycobacterium tuberculosis Conserved hypothetical protein 0.0126 0.0191 0.1124
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0063 0.0065 0.0065
Echinococcus granulosus glutamate receptor 2 0.0041 0.0019 0.0019
Echinococcus granulosus microtubule associated protein 2 0.0751 0.1439 0.1439
Loa Loa (eye worm) hypothetical protein 0.0103 0.0144 0.0144
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.024 0.0418 1
Brugia malayi Calcitonin receptor-like protein seb-1 0.0103 0.0144 0.0144
Loa Loa (eye worm) hypothetical protein 0.0851 0.1638 0.1638
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0041 0.002 0.0358
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0039 0.0016 0.0056
Onchocerca volvulus 0.0053 0.0044 0.0271
Trypanosoma cruzi hypothetical protein, conserved 0.0039 0.0016 0.0264
Schistosoma mansoni gabp alpha 0.007 0.0078 0.0078
Echinococcus multilocularis BC026374 protein (S09 family) 0.0851 0.1638 0.1638
Mycobacterium ulcerans acyl-CoA synthetase 0.0049 0.0036 0.0152
Loa Loa (eye worm) carboxylesterase 0.0851 0.1638 0.1638
Loa Loa (eye worm) hypothetical protein 0.0049 0.0036 0.0036
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0016
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0039 0.0016 0.0016
Mycobacterium ulcerans lipase LipD 0.0039 0.0016 0.0031
Loa Loa (eye worm) hypothetical protein 0.5037 1 1
Brugia malayi AMP-binding enzyme family protein 0.0049 0.0036 0.0036
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0114 0.0165 0.0165
Schistosoma mansoni hypothetical protein 0.0033 0.0003 0.0003
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0063 0.0065 0.0065
Brugia malayi Ets-domain containing protein 0.007 0.0078 0.0078
Schistosoma mansoni survival motor neuron protein 0.0053 0.0044 0.0044
Entamoeba histolytica hypothetical protein 0.0114 0.0165 1
Brugia malayi Ets-domain containing protein 0.007 0.0078 0.0078
Loa Loa (eye worm) hypothetical protein 0.0851 0.1638 0.1638
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0114 0.0165 0.3705
Mycobacterium tuberculosis Probable lipase LipE 0.0039 0.0016 0.0056
Loa Loa (eye worm) hypothetical protein 0.0039 0.0016 0.0016
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0039 0.0016 0.0031
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0041 0.0019 0.0019
Trichomonas vaginalis bromodomain-containing protein, putative 0.0049 0.0036 0.012
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0033 0.0003 0.0003
Onchocerca volvulus 0.0851 0.1638 1
Mycobacterium ulcerans aldehyde dehydrogenase 0.007 0.0077 0.0406
Echinococcus granulosus family S9 non peptidase ue S09 family 0.0851 0.1638 0.1638
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0049 0.0036 0.0176
Mycobacterium ulcerans hypothetical protein 0.0126 0.0191 0.1102
Schistosoma mansoni hypothetical protein 0.0053 0.0044 0.0044
Schistosoma mansoni microtubule-associated protein tau 0.0751 0.1439 0.1439
Schistosoma mansoni glutamate receptor NMDA 0.0041 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0152 0.0242 0.0242
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0103 0.0144 0.0144
Echinococcus granulosus para nitrobenzyl esterase 0.0851 0.1638 0.1638
Echinococcus granulosus GPCR family 2 0.0033 0.0003 0.0003
Schistosoma mansoni aldehyde dehydrogenase 0.007 0.0077 0.0077
Echinococcus multilocularis family S9 non peptidase ue (S09 family) 0.0851 0.1638 0.1638
Mycobacterium tuberculosis Carboxylesterase LipT 0.0851 0.1638 1
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0049 0.0036 0.3301
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0049 0.0036 1
Mycobacterium tuberculosis Conserved protein 0.0039 0.0016 0.0056
Schistosoma mansoni family S9 non-peptidase homologue (S09 family) 0.0851 0.1638 0.1638
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0069 0.0075 0.5
Mycobacterium tuberculosis POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) 0.0851 0.1638 1
Entamoeba histolytica hypothetical protein 0.0114 0.0165 1
Echinococcus multilocularis acetylcholinesterase 0.5037 1 1
Echinococcus multilocularis GPCR, family 2 0.0033 0.0003 0.0003
Trichomonas vaginalis spcc417.12 protein, putative 0.0851 0.1638 1
Loa Loa (eye worm) fli-1 protein 0.0212 0.0362 0.0362
Toxoplasma gondii ABC1 family protein 0.0039 0.0016 0.0153
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.007 0.0077 0.1521
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0049 0.0036 1
Brugia malayi hypothetical protein 0.0851 0.1638 0.1638
Leishmania major mitochondrial DNA polymerase beta 0.024 0.0418 1
Echinococcus multilocularis nmda type glutamate receptor 0.0095 0.0129 0.0129
Loa Loa (eye worm) hypothetical protein 0.0851 0.1638 0.1638

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.