Detailed information for compound 797365

Basic information

Technical information
  • TDR Targets ID: 797365
  • Name: N-(3-thiocyanato-4,5,6,7-tetrahydro-1-benzoth iophen-2-yl)benzamide
  • MW: 314.425 | Formula: C16H14N2OS2
  • H donors: 1 H acceptors: 2 LogP: 4.56 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: N#CSc1c(NC(=O)c2ccccc2)sc2c1CCCC2
  • InChi: 1S/C16H14N2OS2/c17-10-20-14-12-8-4-5-9-13(12)21-16(14)18-15(19)11-6-2-1-3-7-11/h1-3,6-7H,4-5,8-9H2,(H,18,19)
  • InChiKey: YAWCUSGSEQWZJW-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(3-thiocyanato-4,5,6,7-tetrahydrobenzothiophen-2-yl)benzamide
  • BAS 01026463
  • N-(3-Thiocyanato-4,5,6,7-tetrahydro-benzo[b]thiophen-2-yl)-benzamide
  • Oprea1_691527
  • Oprea1_786014
  • A2187/0091940
  • ZINC00053357

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Plasmodium vivax enoyl-acyl carrier protein reductase 0.0183 0.5254 1
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0081 0.2076 1
Trypanosoma cruzi hypothetical protein, conserved 0.0056 0.1285 0.6188
Trichomonas vaginalis casein kinase II beta chain, putative 0.0024 0.0287 0.0543
Loa Loa (eye worm) casein kinase II 0.0024 0.0287 0.0761
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0056 0.1285 0.2443
Onchocerca volvulus 0.0015 0.0012 0.0059
Toxoplasma gondii PAN domain-containing protein 0.0036 0.0672 0.0672
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0081 0.2076 1
Plasmodium vivax phospholipase C-like, putative 0.0019 0.0126 0.0236
Loa Loa (eye worm) PAN domain-containing protein 0.0036 0.0672 0.1782
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0012 0.0059
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0639 0.1214
Loa Loa (eye worm) hypothetical protein 0.0037 0.0702 0.1864
Onchocerca volvulus 0.002 0.0161 0.0774
Brugia malayi Chymotrypsin-like protease CTRL-1 precursor 0.0015 0.0012 0.0033
Giardia lamblia Casein kinase II beta chain 0.0081 0.2076 1
Trichomonas vaginalis protein kinase ck2-beta, putative 0.0024 0.0287 0.0543
Onchocerca volvulus 0.0015 0.0002 0.001
Loa Loa (eye worm) hypothetical protein 0.0036 0.0672 0.1782
Toxoplasma gondii ck2 beta subunit 0.0081 0.2076 0.2076
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0012 0.0059
Brugia malayi Kringle domain containing protein 0.0056 0.1285 0.341
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0002 0.0005
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0024 0.0287 0.1374
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0012 0.0059
Brugia malayi AMP-binding enzyme family protein 0.005 0.1093 0.2899
Wolbachia endosymbiont of Brugia malayi enoyl-ACP reductase 0.0183 0.5254 0.5
Mycobacterium ulcerans hypothetical protein 0.005 0.1093 0.2077
Plasmodium falciparum phosphoinositide-specific phospholipase C 0.0019 0.0126 0.0236
Brugia malayi Trypsin family protein 0.0015 0.0012 0.0033
Echinococcus multilocularis tissue type plasminogen activator 0.0056 0.1285 0.6191
Loa Loa (eye worm) hypothetical protein 0.005 0.1093 0.2899
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0081 0.2076 1
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0015 0.0002 0.0002
Brugia malayi PAN domain containing protein 0.0036 0.0672 0.1782
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.1093 0.2077
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0012 0.0059
Loa Loa (eye worm) hypothetical protein 0.0037 0.0702 0.1864
Loa Loa (eye worm) oxidoreductase 0.0015 0.0002 0.0005
Toxoplasma gondii enoyl-acyl carrier reductase ENR 0.0183 0.5254 0.5254
Brugia malayi Trypsin family protein 0.0015 0.0012 0.0033
Toxoplasma gondii kringle domain-containing protein 0.0056 0.1285 0.1285
Trypanosoma brucei Casein kinase II subunit beta, putative 0.0081 0.2076 1
Toxoplasma gondii PAN/Apple domain-containing protein 0.0036 0.0672 0.0672
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0002 0.0005
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.1093 0.5259
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0639 0.1214
Trypanosoma brucei phosphoinositide-specific phospholipase C 0.002 0.0161 0.0766
Loa Loa (eye worm) phosphatidylinositol-specific phospholipase C 0.002 0.0161 0.0427
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.1093 0.2077
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0012 0.0059
Trichomonas vaginalis casein kinase II beta chain, putative 0.0024 0.0287 0.0543
Echinococcus granulosus transmembrane protease serine 3 0.0015 0.0012 0.0059
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Plasmodium falciparum acyl-CoA synthetase 0.0037 0.0702 0.1334
Mycobacterium ulcerans hypothetical protein 0.0015 0.0012 0.002
Toxoplasma gondii microneme protein MIC4 0.0036 0.0672 0.0672
Plasmodium vivax casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Loa Loa (eye worm) trypsin family protein 0.0015 0.0012 0.0033
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0015 0.0002 0.0002
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.005 0.1093 0.2077
Loa Loa (eye worm) PAN domain-containing protein 0.0036 0.0672 0.1782
Trichomonas vaginalis casein kinase II beta chain, putative 0.0024 0.0287 0.0543
Loa Loa (eye worm) variant SH3 domain-containing protein 0.0136 0.3769 1
Leishmania major protein kinase ck2 regulatory subunit, putative 0.0081 0.2076 1
Brugia malayi hypothetical protein 0.0015 0.0012 0.0033
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.005 0.1093 0.2077
Trichomonas vaginalis casein kinase II beta chain, putative 0.0024 0.0287 0.0543
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0012 0.0059
Echinococcus granulosus casein kinase ii subunit beta 0.0081 0.2076 1
Trichomonas vaginalis protein kinase ck2-beta, putative 0.0024 0.0287 0.0543
Echinococcus multilocularis glycoprotein Antigen 5 0.0015 0.0012 0.0059
Echinococcus granulosus tissue type plasminogen activator 0.0056 0.1285 0.6191
Brugia malayi PAN domain containing protein 0.0036 0.0672 0.1782
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0015 0.0002 0.001
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.1093 0.2077
Trichomonas vaginalis hypothetical protein 0.0183 0.5254 1
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0012 0.0059
Echinococcus multilocularis Mastin 0.0015 0.0012 0.0059
Echinococcus multilocularis casein kinase ii subunit beta 0.0081 0.2076 1
Loa Loa (eye worm) hypothetical protein 0.0037 0.0702 0.1864
Brugia malayi PAN domain containing protein 0.0036 0.0672 0.1782
Brugia malayi PAN domain containing protein 0.0036 0.0672 0.1782
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0012 0.0059
Trichomonas vaginalis casein kinase II beta chain, putative 0.0024 0.0287 0.0543
Trichomonas vaginalis casein kinase II beta chain, putative 0.0024 0.0287 0.0543
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.1093 0.5259
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0033
Onchocerca volvulus 0.0036 0.0672 0.3235
Echinococcus granulosus Mastin 0.0015 0.0012 0.0059
Toxoplasma gondii microneme protein, putative 0.0036 0.0672 0.0672
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Plasmodium falciparum casein kinase II beta chain 0.0081 0.2076 0.3949
Toxoplasma gondii PAN domain-containing protein 0.0036 0.0672 0.0672
Brugia malayi PAN domain containing protein 0.0036 0.0672 0.1782
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Brugia malayi AMP-binding enzyme family protein 0.005 0.1093 0.2899
Mycobacterium ulcerans fatty-acid-CoA ligase 0.005 0.1093 0.2077
Brugia malayi AMP-binding enzyme family protein 0.005 0.1093 0.2899
Toxoplasma gondii 1,3(4)-beta-glucanase 0.0036 0.0672 0.0672
Leishmania major phospholipase c-like protein 0.002 0.0161 0.0766
Trichomonas vaginalis casein kinase II beta chain, putative 0.0024 0.0287 0.0543
Leishmania major phosphoinositide-specific phospholipase C, putative 0.0019 0.0126 0.0598
Echinococcus multilocularis Peptidase S1 S6, chymotrypsin Hap 0.0015 0.0012 0.0059
Echinococcus multilocularis 1 phosphatidylinositol 4,5 bisphosphate 0.002 0.0161 0.0774
Mycobacterium leprae NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) 0.0183 0.5254 1
Toxoplasma gondii hypothetical protein 0.0036 0.0672 0.0672
Onchocerca volvulus 0.002 0.0161 0.0774
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.005 0.1093 0.2077
Trypanosoma cruzi phosphoinositide-specific phospholipase C, putative 0.002 0.0161 0.0766
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0037 0.0702 0.1334
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.0019 0.0126 0.0334
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0012 0.0059
Schistosoma mansoni phospholipase C beta 0.0019 0.0126 0.0607
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0015 0.0012 0.0059
Echinococcus granulosus 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 0.002 0.0161 0.0774
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Onchocerca volvulus 0.0036 0.0672 0.3235
Loa Loa (eye worm) hypothetical protein 0.002 0.0161 0.0427
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0012 0.0059
Onchocerca volvulus 0.0036 0.0672 0.3235
Leishmania major 4-coumarate:coa ligase-like protein 0.005 0.1093 0.5259
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.1093 0.5259
Loa Loa (eye worm) hypothetical protein 0.0036 0.0672 0.1782
Echinococcus multilocularis transmembrane protease serine 3 0.0015 0.0012 0.0059
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0081 0.2076 1
Brugia malayi Csnk2b protein 0.0081 0.2076 0.5508
Loa Loa (eye worm) PAN domain-containing protein 0.0036 0.0672 0.1782
Onchocerca volvulus 0.0036 0.0672 0.3235
Loa Loa (eye worm) hypothetical protein 0.0036 0.0672 0.1782
Brugia malayi Trypsin family protein 0.0015 0.0012 0.0033
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0033
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0012 0.0059
Loa Loa (eye worm) PAN domain-containing protein 0.0036 0.0672 0.1782
Toxoplasma gondii PAN domain-containing protein 0.0036 0.0672 0.0672
Loa Loa (eye worm) hypothetical protein 0.0019 0.0126 0.0334
Onchocerca volvulus 0.0036 0.0672 0.3235
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0033
Loa Loa (eye worm) Csnk2b protein 0.0081 0.2076 0.5508
Loa Loa (eye worm) hypothetical protein 0.0036 0.0672 0.1782
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0002 0.0005
Toxoplasma gondii propionate-CoA ligase 0.0015 0.0002 0.0002
Toxoplasma gondii PAN domain-containing protein 0.0336 1 1
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0012 0.0059
Loa Loa (eye worm) hypothetical protein 0.0037 0.0702 0.1864
Onchocerca volvulus 0.0015 0.0002 0.001
Leishmania major hypothetical protein, conserved 0.0056 0.1285 0.6188
Mycobacterium tuberculosis NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) 0.0183 0.5254 1
Echinococcus granulosus subfamily S1A unassigned peptidase S01 family 0.0015 0.0012 0.0059
Onchocerca volvulus 0.0015 0.0012 0.0059
Toxoplasma gondii PAN domain-containing protein 0.0036 0.0672 0.0672
Leishmania major phosphatidylinositol-specific phospholipase-like protein 0.0019 0.0126 0.0598
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.005 0.1093 0.2077
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.1093 0.2077
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0081 0.2076 1
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0033
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0015 0.0002 0.001
Onchocerca volvulus 0.0015 0.0002 0.001
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0012 0.0059
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0005
Trichomonas vaginalis casein kinase II beta chain, putative 0.0024 0.0287 0.0543
Loa Loa (eye worm) hypothetical protein 0.0036 0.0672 0.1782
Echinococcus multilocularis subfamily S1A unassigned peptidase (S01 family) 0.0015 0.0012 0.0059
Schistosoma mansoni casein kinase II beta subunit 0.0081 0.2076 1
Toxoplasma gondii hypothetical protein 0.0036 0.0672 0.0672
Brugia malayi PAN domain containing protein 0.0036 0.0672 0.1782
Onchocerca volvulus Casein kinase II subunit beta homolog 0.0081 0.2076 1
Entamoeba histolytica acyl-coA synthetase, putative 0.005 0.1093 0.5259
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Echinococcus granulosus Peptidase S1 S6 chymotrypsin Hap 0.0015 0.0012 0.0059
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0012 0.0059
Entamoeba histolytica acyl-CoA synthetase, putative 0.005 0.1093 0.5259
Toxoplasma gondii casein kinase ii regulatory subunit protein 0.0081 0.2076 0.2076
Schistosoma mansoni hypothetical protein 0.0015 0.0012 0.0059
Mycobacterium ulcerans acyl-CoA synthetase 0.005 0.1093 0.2077
Brugia malayi PAN domain containing protein 0.0036 0.0672 0.1782
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Chlamydia trachomatis enoyl-acyl-carrier protein reductase 0.0183 0.5254 1
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0015 0.0002 0.0005
Trichomonas vaginalis casein kinase II beta chain, putative 0.0024 0.0287 0.0543
Trichomonas vaginalis casein kinase II beta chain, putative 0.0024 0.0287 0.0543
Plasmodium falciparum enoyl-acyl carrier reductase 0.0183 0.5254 1
Plasmodium vivax acyl-CoA synthetase, putative 0.0037 0.0702 0.1334
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0015 0.0002 0.0005
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0639 0.1214
Brugia malayi 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 0.0019 0.0126 0.0334
Onchocerca volvulus 0.0036 0.0672 0.3235
Schistosoma mansoni acetyl-CoA synthetase 0.0015 0.0002 0.001
Toxoplasma gondii microneme protein MIC17C 0.0036 0.0672 0.0672
Onchocerca volvulus 0.0036 0.0672 0.3235
Onchocerca volvulus 0.0015 0.0012 0.0059
Toxoplasma gondii microneme protein MIC17B 0.0036 0.0672 0.0672
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0037 0.0702 0.1334
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0012 0.0059
Onchocerca volvulus 0.0036 0.0672 0.3235
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.005 0.1093 0.2077
Toxoplasma gondii microneme protein MIC17A 0.0036 0.0672 0.0672
Toxoplasma gondii phosphoinositide phospholipase PIPLC 0.002 0.0161 0.0161
Schistosoma mansoni hypothetical protein 0.0056 0.1285 0.6191
Onchocerca volvulus 0.0056 0.1285 0.6191
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0033
Onchocerca volvulus 0.0036 0.0672 0.3235
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0002 0.0005
Loa Loa (eye worm) hypothetical protein 0.0056 0.1285 0.341
Onchocerca volvulus 0.0015 0.0002 0.001
Schistosoma mansoni hypothetical protein 0.0015 0.0012 0.0059
Onchocerca volvulus 0.005 0.1093 0.5264
Trichomonas vaginalis casein kinase II beta chain, putative 0.0024 0.0287 0.0543
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0012 0.0059
Loa Loa (eye worm) hypothetical protein 0.002 0.0161 0.0427
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0015 0.0002 0.0005
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Onchocerca volvulus 0.0015 0.0012 0.0059
Echinococcus multilocularis enteropeptidase 0.0015 0.0012 0.0059
Brugia malayi Trypsin-like protease protein 5 0.0015 0.0012 0.0033
Onchocerca volvulus 0.0015 0.0012 0.0059
Trichomonas vaginalis casein kinase II beta chain, putative 0.0024 0.0287 0.0543
Brugia malayi Variant SH3 domain containing protein 0.0136 0.3769 1
Trypanosoma cruzi Casein kinase II subunit beta, putative 0.0081 0.2076 1
Brugia malayi AMP-binding enzyme family protein 0.0015 0.0002 0.0005
Mycobacterium ulcerans enoyl-(acyl carrier protein) reductase 0.0183 0.5254 1
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0035 0.0639 0.1214
Brugia malayi PAN domain containing protein 0.0036 0.0672 0.1782
Loa Loa (eye worm) TK/ROR protein kinase 0.0056 0.1285 0.341
Brugia malayi Phosphatidylinositol-specific phospholipase C, X domain containing protein 0.002 0.0161 0.0427
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Plasmodium vivax casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Loa Loa (eye worm) hypothetical protein 0.005 0.1093 0.2899
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0012 0.0059
Brugia malayi casein kinase II, putaitve 0.0024 0.0287 0.0761
Plasmodium falciparum cysteine repeat modular protein 1 0.0056 0.1285 0.2443
Onchocerca volvulus 0.0036 0.0672 0.3235
Echinococcus granulosus glycoprotein Antigen 5 0.0015 0.0012 0.0059
Brugia malayi PAN domain containing protein 0.0036 0.0672 0.1782
Loa Loa (eye worm) hypothetical protein 0.0037 0.0702 0.1864
Loa Loa (eye worm) hypothetical protein 0.005 0.1093 0.2899
Trichomonas vaginalis casein kinase II beta chain, putative 0.0024 0.0287 0.0543
Onchocerca volvulus 0.0036 0.0672 0.3235
Onchocerca volvulus 0.0015 0.0012 0.0059
Loa Loa (eye worm) hypothetical protein 0.0015 0.0002 0.0005
Brugia malayi Protein kinase domain containing protein 0.0056 0.1285 0.341
Brugia malayi Trypsin family protein 0.0015 0.0012 0.0033
Schistosoma mansoni cercarial elastase (S01 family) 0.0015 0.0012 0.0059
Loa Loa (eye worm) hypothetical protein 0.0036 0.0672 0.1782
Toxoplasma gondii subtilisin SUB12 0.0036 0.0672 0.0672
Loa Loa (eye worm) Plcb4 protein 0.0019 0.0126 0.0334
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Entamoeba histolytica casein kinase II regulatory subunit family protein 0.0024 0.0287 0.1374
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0033
Brugia malayi PAN domain containing protein 0.0036 0.0672 0.1782
Loa Loa (eye worm) hypothetical protein 0.0036 0.0672 0.1782
Loa Loa (eye worm) hypothetical protein 0.0015 0.0012 0.0033
Plasmodium falciparum casein kinase II beta chain 0.0081 0.2076 0.3949
Trichomonas vaginalis casein kinase II beta chain, putative 0.0081 0.2076 0.3949
Echinococcus granulosus enteropeptidase 0.0015 0.0012 0.0059
Loa Loa (eye worm) PAN domain-containing protein 0.0036 0.0672 0.1782

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.