Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0017 | 0.0114 | 0.5 |
Chlamydia trachomatis | acylglycerophosphoethanolamine acyltransferase | 0.0017 | 0.0114 | 0.5 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0023 | 0.1149 | 0.5 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0023 | 0.1149 | 1 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.1149 | 0.5 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0022 | 0.0947 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1149 | 0.124 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0023 | 0.1149 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0114 | 0.0123 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.1149 | 0.5 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0022 | 0.0947 | 0.1287 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1149 | 0.124 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1149 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0023 | 0.1149 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0114 | 0.0123 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1149 | 1 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.1149 | 1 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0023 | 0.1149 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0069 | 0.9262 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0114 | 0.0123 |
Echinococcus granulosus | zinc finger protein | 0.0019 | 0.0435 | 0.0592 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0023 | 0.1149 | 1 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0022 | 0.0947 | 0.1188 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1149 | 0.5 |
Schistosoma mansoni | zinc finger protein | 0.0019 | 0.0435 | 0.0546 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0023 | 0.1149 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.1149 | 0.124 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0023 | 0.1149 | 1 |
Onchocerca volvulus | 0.0023 | 0.1149 | 0.5 | |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1149 | 0.5 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0035 | 0.3258 | 0.4427 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0058 | 0.736 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0023 | 0.1149 | 0.5 |
Loa Loa (eye worm) | bromodomain containing protein | 0.0017 | 0.0106 | 0.0114 |
Brugia malayi | PHD-finger family protein | 0.0024 | 0.1356 | 0.0234 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0114 | 0.0123 |
Mycobacterium leprae | PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) | 0.0023 | 0.1149 | 0.5 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0017 | 0.0114 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0042 | 0.4417 | 0.4769 |
Schistosoma mansoni | hypothetical protein | 0.002 | 0.0618 | 0.0774 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0023 | 0.1149 | 1 |
Echinococcus multilocularis | zinc finger protein | 0.0019 | 0.0435 | 0.0592 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0058 | 0.736 | 1 |
Loa Loa (eye worm) | PHD-finger family protein | 0.002 | 0.0618 | 0.0667 |
Brugia malayi | Bromodomain containing protein | 0.0038 | 0.3667 | 0.2845 |
Loa Loa (eye worm) | hypothetical protein | 0.0038 | 0.3679 | 0.3972 |
Loa Loa (eye worm) | hypothetical protein | 0.004 | 0.4087 | 0.4413 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0035 | 0.3258 | 0.4427 |
Schistosoma mansoni | bromodomain containing protein | 0.0062 | 0.7978 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0114 | 0.0123 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.