TDR Targets

Basic information

Technical information

Name: Unnamed compound
MW: 325.324 | Formula: C19H11N5O
H donors: 2 H acceptors: 4 LogP: 3.28 Rotable bonds: 1
Rule of 5 violations (Lipinski): 1
SMILES: N#Cc1c(c2ccc(cc2)O)c(C#N)c2n(c1N)c1ccccc1n2
InChi: 1S/C19H11N5O/c20-9-13-17(11-5-7-12(25)8-6-11)14(10-21)19-23-15-3-1-2-4-16(15)24(19)18(13)22/h1-8,25H,22H2
InChiKey: DMVRZVGBLGRJRA-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Plasmodium falciparum	casein kinase II beta chain	0.0074	0.1946	0.3629
Mycobacterium ulcerans	hypothetical protein	0.0014	0.001	0.0018
Brugia malayi	Variant SH3 domain containing protein	0.013	0.3768	1
Mycobacterium leprae	NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE)	0.0179	0.5364	1
Loa Loa (eye worm)	hypothetical protein	0.0048	0.1092	0.2899
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Toxoplasma gondii	microneme protein MIC17C	0.0035	0.0669	0.0669
Loa Loa (eye worm)	hypothetical protein	0.0014	0.001	0.0026
Plasmodium vivax	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Brugia malayi	PAN domain containing protein	0.0035	0.0669	0.1776
Echinococcus granulosus	subfamily S1A unassigned peptidase S01 family	0.0014	0.001	0.005
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0701	0.1861
Plasmodium falciparum	acyl-CoA synthetase	0.0036	0.0701	0.1308
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0669	0.1776
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0022	0.0247	0.0461
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0669	0.1776
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0036	0.0701	0.1308
Brugia malayi	Trypsin family protein	0.0014	0.001	0.0026
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.0014	0.001	0.005
Trypanosoma brucei	Casein kinase II subunit beta, putative	0.0074	0.1946	1
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.001	0.005
Onchocerca volvulus		0.0035	0.0669	0.3438
Brugia malayi	Chymotrypsin-like protease CTRL-1 precursor	0.0014	0.001	0.0026
Loa Loa (eye worm)	PAN domain-containing protein	0.0035	0.0669	0.1776
Toxoplasma gondii	PAN domain-containing protein	0.0035	0.0669	0.0669
Brugia malayi	hypothetical protein	0.0014	0.001	0.0026
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0022	0.0247	0.0461
Echinococcus granulosus	1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4	0.0019	0.0158	0.0814
Brugia malayi	Trypsin family protein	0.0014	0.001	0.0026
Trichomonas vaginalis	protein kinase ck2-beta, putative	0.0022	0.0247	0.0461
Plasmodium falciparum	phosphoinositide-specific phospholipase C	0.0018	0.0124	0.0231
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0158	0.042
Echinococcus multilocularis	Mastin	0.0014	0.001	0.005
Loa Loa (eye worm)	hypothetical protein	0.0018	0.0124	0.0328
Brugia malayi	Trypsin-like protease protein 5	0.0014	0.001	0.0026
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.001	0.005
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0034	0.0638	0.119
Toxoplasma gondii	PAN domain-containing protein	0.0035	0.0669	0.0669
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0048	0.1092	0.2036
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.0074	0.1946	1
Toxoplasma gondii	microneme protein MIC4	0.0035	0.0669	0.0669
Leishmania major	4-coumarate:coa ligase-like protein	0.0048	0.1092	0.5612
Chlamydia trachomatis	enoyl-acyl-carrier protein reductase	0.0179	0.5364	1
Plasmodium vivax	acyl-CoA synthetase, putative	0.0036	0.0701	0.1308
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Loa Loa (eye worm)	trypsin family protein	0.0014	0.001	0.0026
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.001	0.005
Brugia malayi	AMP-binding enzyme family protein	0.0048	0.1092	0.2899
Brugia malayi	Trypsin family protein	0.0014	0.001	0.0026
Brugia malayi	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4	0.0018	0.0124	0.0328
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.001	0.005
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0022	0.0247	0.0461
Onchocerca volvulus		0.0035	0.0669	0.3438
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.001	0.005
Loa Loa (eye worm)	hypothetical protein	0.0048	0.1092	0.2899
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0022	0.0247	0.0461
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.0074	0.1946	1
Onchocerca volvulus		0.0014	0.001	0.005
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0022	0.0247	0.0461
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.001	0.005
Plasmodium falciparum	enoyl-acyl carrier reductase	0.0179	0.5364	1
Echinococcus granulosus	transmembrane protease serine 3	0.0014	0.001	0.005
Loa Loa (eye worm)	PAN domain-containing protein	0.0035	0.0669	0.1776
Leishmania major	protein kinase ck2 regulatory subunit, putative	0.0074	0.1946	1
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0034	0.0638	0.119
Brugia malayi	PAN domain containing protein	0.0035	0.0669	0.1776
Brugia malayi	PAN domain containing protein	0.0035	0.0669	0.1776
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Onchocerca volvulus		0.0014	0.001	0.005
Leishmania major	phospholipase c-like protein	0.0019	0.0158	0.0814
Toxoplasma gondii	subtilisin SUB12	0.0035	0.0669	0.0669
Onchocerca volvulus		0.0053	0.1283	0.6592
Loa Loa (eye worm)	hypothetical protein	0.0014	0.001	0.0026
Toxoplasma gondii	microneme protein MIC17B	0.0035	0.0669	0.0669
Loa Loa (eye worm)	TK/ROR protein kinase	0.0053	0.1283	0.3405
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0701	0.1861
Echinococcus multilocularis	glycoprotein Antigen 5	0.0014	0.001	0.005
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0701	0.1861
Plasmodium falciparum	casein kinase II beta chain	0.0074	0.1946	0.3629
Loa Loa (eye worm)	hypothetical protein	0.0014	0.001	0.0026
Trypanosoma cruzi	hypothetical protein, conserved	0.0053	0.1283	0.6592
Brugia malayi	AMP-binding enzyme family protein	0.0048	0.1092	0.2899
Toxoplasma gondii	microneme protein, putative	0.0035	0.0669	0.0669
Entamoeba histolytica	acyl-coA synthetase, putative	0.0048	0.1092	0.5612
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0048	0.1092	0.2036
Onchocerca volvulus		0.0035	0.0669	0.3438
Toxoplasma gondii	microneme protein MIC17A	0.0035	0.0669	0.0669
Brugia malayi	Protein kinase domain containing protein	0.0053	0.1283	0.3405
Brugia malayi	PAN domain containing protein	0.0035	0.0669	0.1776
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0669	0.1776
Echinococcus granulosus	glycoprotein Antigen 5	0.0014	0.001	0.005
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0048	0.1092	0.2036
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0048	0.1092	0.2036
Toxoplasma gondii	casein kinase ii regulatory subunit protein	0.0074	0.1946	0.1946
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0048	0.1092	0.2036
Onchocerca volvulus		0.0014	0.001	0.005
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.001	0.005
Onchocerca volvulus		0.0014	0.001	0.005
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0022	0.0247	0.0461
Onchocerca volvulus		0.0035	0.0669	0.3438
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0048	0.1092	0.2036
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Onchocerca volvulus		0.0019	0.0158	0.0814
Brugia malayi	PAN domain containing protein	0.0035	0.0669	0.1776
Echinococcus multilocularis	casein kinase ii subunit beta	0.0074	0.1946	1
Loa Loa (eye worm)	hypothetical protein	0.0014	0.001	0.0026
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.0022	0.0247	0.127
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0669	0.1776
Echinococcus multilocularis	transmembrane protease serine 3	0.0014	0.001	0.005
Schistosoma mansoni	casein kinase II beta subunit	0.0074	0.1946	1
Toxoplasma gondii	enoyl-acyl carrier reductase ENR	0.0179	0.5364	0.5364
Loa Loa (eye worm)	hypothetical protein	0.0053	0.1283	0.3405
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.0022	0.0247	0.127
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.001	0.005
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0022	0.0247	0.0461
Loa Loa (eye worm)	hypothetical protein	0.0014	0.001	0.0026
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.001	0.005
Toxoplasma gondii	1,3(4)-beta-glucanase	0.0035	0.0669	0.0669
Trypanosoma cruzi	Casein kinase II subunit beta, putative	0.0074	0.1946	1
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0022	0.0247	0.0461
Onchocerca volvulus		0.0035	0.0669	0.3438
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.001	0.005
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0036	0.0701	0.1308
Loa Loa (eye worm)	Plcb4 protein	0.0018	0.0124	0.0328
Brugia malayi	PAN domain containing protein	0.0035	0.0669	0.1776
Echinococcus multilocularis	1 phosphatidylinositol 4,5 bisphosphate	0.0019	0.0158	0.0814
Schistosoma mansoni	hypothetical protein	0.0053	0.1283	0.6592
Brugia malayi	Csnk2b protein	0.0074	0.1946	0.5166
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Mycobacterium tuberculosis	NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase)	0.0179	0.5364	1
Onchocerca volvulus	Casein kinase II subunit beta homolog	0.0074	0.1946	1
Loa Loa (eye worm)	hypothetical protein	0.0014	0.001	0.0026
Trypanosoma cruzi	phosphoinositide-specific phospholipase C, putative	0.0019	0.0158	0.0814
Mycobacterium ulcerans	acyl-CoA synthetase	0.0048	0.1092	0.2036
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Brugia malayi	PAN domain containing protein	0.0035	0.0669	0.1776
Onchocerca volvulus		0.0019	0.0158	0.0814
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Loa Loa (eye worm)	casein kinase II	0.0022	0.0247	0.0656
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0669	0.1776
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.001	0.005
Echinococcus granulosus	enteropeptidase	0.0014	0.001	0.005
Leishmania major	4-coumarate:coa ligase-like protein	0.0048	0.1092	0.5612
Trichomonas vaginalis	hypothetical protein	0.0179	0.5364	1
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0022	0.0247	0.0461
Loa Loa (eye worm)	PAN domain-containing protein	0.0035	0.0669	0.1776
Echinococcus multilocularis	tissue type plasminogen activator	0.0053	0.1283	0.6592
Loa Loa (eye worm)	Csnk2b protein	0.0074	0.1946	0.5166
Leishmania major	phosphoinositide-specific phospholipase C, putative	0.0018	0.0124	0.0635
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.001	0.005
Trypanosoma brucei	phosphoinositide-specific phospholipase C	0.0019	0.0158	0.0814
Schistosoma mansoni	phospholipase C beta	0.0018	0.0124	0.0635
Onchocerca volvulus	Casein kinase II subunit beta homolog	0.0074	0.1946	1
Brugia malayi	Kringle domain containing protein	0.0053	0.1283	0.3405
Onchocerca volvulus		0.0014	0.001	0.005
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.001	0.005
Onchocerca volvulus		0.0048	0.1092	0.5612
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0048	0.1092	0.2036
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.001	0.005
Toxoplasma gondii	hypothetical protein	0.0035	0.0669	0.0669
Toxoplasma gondii	PAN domain-containing protein	0.0035	0.0669	0.0669
Brugia malayi	casein kinase II, putaitve	0.0022	0.0247	0.0656
Onchocerca volvulus		0.0014	0.001	0.005
Onchocerca volvulus		0.0035	0.0669	0.3438
Echinococcus multilocularis	Peptidase S1 S6, chymotrypsin Hap	0.0014	0.001	0.005
Echinococcus granulosus	tissue type plasminogen activator	0.0053	0.1283	0.6592
Onchocerca volvulus		0.0035	0.0669	0.3438
Mycobacterium ulcerans	acyl-CoA synthetase	0.0048	0.1092	0.2036
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.013	0.3768	1
Onchocerca volvulus		0.0035	0.0669	0.3438
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.001	0.005
Mycobacterium ulcerans	enoyl-(acyl carrier protein) reductase	0.0179	0.5364	1
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0022	0.0247	0.0461
Onchocerca volvulus		0.0035	0.0669	0.3438
Onchocerca volvulus		0.0035	0.0669	0.3438
Toxoplasma gondii	phosphoinositide phospholipase PIPLC	0.0019	0.0158	0.0158
Brugia malayi	PAN domain containing protein	0.0035	0.0669	0.1776
Toxoplasma gondii	kringle domain-containing protein	0.0053	0.1283	0.1283
Toxoplasma gondii	ck2 beta subunit	0.0074	0.1946	0.1946
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0701	0.1861
Echinococcus granulosus	casein kinase ii subunit beta	0.0074	0.1946	1
Trypanosoma cruzi	Casein kinase II subunit beta, putative	0.0074	0.1946	1
Brugia malayi	AMP-binding enzyme family protein	0.0048	0.1092	0.2899
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.001	0.005
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0048	0.1092	0.5612
Brugia malayi	PAN domain containing protein	0.0035	0.0669	0.1776
Brugia malayi	PAN domain containing protein	0.0035	0.0669	0.1776
Giardia lamblia	Casein kinase II beta chain	0.0074	0.1946	1
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0048	0.1092	0.2036
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0669	0.1776
Loa Loa (eye worm)	hypothetical protein	0.0036	0.0701	0.1861
Loa Loa (eye worm)	hypothetical protein	0.0014	0.001	0.0026
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0022	0.0247	0.0461
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0022	0.0247	0.0461
Schistosoma mansoni	hypothetical protein	0.0014	0.001	0.005
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.0074	0.1946	1
Echinococcus granulosus	Mastin	0.0014	0.001	0.005
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.001	0.005
Loa Loa (eye worm)	hypothetical protein	0.0048	0.1092	0.2899
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0022	0.0247	0.0461
Wolbachia endosymbiont of Brugia malayi	enoyl-ACP reductase	0.0179	0.5364	0.5
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0048	0.1092	0.5612
Toxoplasma gondii	PAN domain-containing protein	0.0035	0.0669	0.0669
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Trichomonas vaginalis	protein kinase ck2-beta, putative	0.0022	0.0247	0.0461
Plasmodium vivax	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Leishmania major	hypothetical protein, conserved	0.0053	0.1283	0.6592
Toxoplasma gondii	PAN/Apple domain-containing protein	0.0035	0.0669	0.0669
Plasmodium vivax	enoyl-acyl carrier protein reductase	0.0179	0.5364	1
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0034	0.0638	0.119
Onchocerca volvulus		0.0035	0.0669	0.3438
Plasmodium vivax	phospholipase C-like, putative	0.0018	0.0124	0.0231
Brugia malayi	Trypsin family protein	0.0014	0.001	0.0026
Toxoplasma gondii	PAN domain-containing protein	0.0322	1	1
Leishmania major	phosphatidylinositol-specific phospholipase-like protein	0.0018	0.0124	0.0635
Loa Loa (eye worm)	phosphatidylinositol-specific phospholipase C	0.0019	0.0158	0.042
Mycobacterium ulcerans	acyl-CoA synthetase	0.0048	0.1092	0.2036
Leishmania major	4-coumarate:coa ligase-like protein	0.0048	0.1092	0.5612
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0034	0.0638	0.119
Plasmodium falciparum	cysteine repeat modular protein 1	0.0053	0.1283	0.2392
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0669	0.1776
Brugia malayi	Phosphatidylinositol-specific phospholipase C, X domain containing protein	0.0018	0.0124	0.0328
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.001	0.005
Loa Loa (eye worm)	PAN domain-containing protein	0.0035	0.0669	0.1776
Schistosoma mansoni	hypothetical protein	0.0014	0.001	0.005
Brugia malayi	Phosphatidylinositol-specific phospholipase C, X domain containing protein	0.0019	0.0158	0.042
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0074	0.1946	0.3629
Echinococcus multilocularis	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.001	0.005
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0158	0.042
Plasmodium vivax	cysteine repeat modular protein 1, putative	0.0053	0.1283	0.2392
Echinococcus granulosus	Peptidase S1 S6 chymotrypsin Hap	0.0014	0.001	0.005
Loa Loa (eye worm)	PAN domain-containing protein	0.0035	0.0669	0.1776
Echinococcus multilocularis	enteropeptidase	0.0014	0.001	0.005
Mycobacterium ulcerans	hypothetical protein	0.0048	0.1092	0.2036
Toxoplasma gondii	hypothetical protein	0.0035	0.0669	0.0669

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 797582