TDR Targets

Basic information

Technical information

TDR Targets ID: 797583
Name: 4-methyl-5-[(4-methylphenoxy)methyl]-2H-1,2,4 -triazole-3-thione
MW: 235.305 | Formula: C11H13N3OS
H donors: 0 H acceptors: 2 LogP: 1.78 Rotable bonds: 3
Rule of 5 violations (Lipinski): 1
SMILES: Cc1ccc(cc1)OCc1nnc(n1C)S
InChi: 1S/C11H13N3OS/c1-8-3-5-9(6-4-8)15-7-10-12-13-11(16)14(10)2/h3-6H,7H2,1-2H3,(H,13,16)
InChiKey: UJGSEVWOQOHWGU-UHFFFAOYSA-N

Network

Hover on a compound node to display the structore

Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

This is a work in progress. Come back soon to try this features!

Clustering layers

This is a work in progress. Come back soon to try this features!

Synonyms

A2222/0093579
EU-0085729
ZINC00269002

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Toxoplasma gondii	casein kinase ii regulatory subunit protein	0.0072	0.1945	0.1945
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0021	0.0244	0.0437
Onchocerca volvulus		0.0014	0.0005	0.0028
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.0005	0.0028
Toxoplasma gondii	microneme protein MIC17C	0.0033	0.0665	0.0665
Leishmania major	4-coumarate:coa ligase-like protein	0.0046	0.1103	0.5672
Plasmodium vivax	enoyl-acyl carrier protein reductase	0.0179	0.5572	1
Loa Loa (eye worm)	hypothetical protein	0.0046	0.1103	0.2873
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0005	0.0014
Leishmania major	hypothetical protein, conserved	0.0052	0.1279	0.6577
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.0005	0.0028
Plasmodium falciparum	cysteine repeat modular protein 1	0.0052	0.1279	0.2296
Brugia malayi	Trypsin family protein	0.0014	0.0005	0.0014
Brugia malayi	Chymotrypsin-like protease CTRL-1 precursor	0.0014	0.0005	0.0014
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Brugia malayi	casein kinase II, putaitve	0.0021	0.0244	0.0634
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.0005	0.0028
Schistosoma mansoni	hypothetical protein	0.0014	0.0005	0.0028
Loa Loa (eye worm)	hypothetical protein	0.0046	0.1103	0.2873
Loa Loa (eye worm)	PAN domain-containing protein	0.0033	0.0665	0.1732
Echinococcus granulosus	Mastin	0.0014	0.0005	0.0028
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0021	0.0244	0.0437
Loa Loa (eye worm)	variant SH3 domain-containing protein	0.0128	0.384	1
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.0005	0.0028
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0021	0.0244	0.0437
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0021	0.0244	0.0437
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.0005	0.0028
Schistosoma mansoni	casein kinase II beta subunit	0.0072	0.1945	1
Mycobacterium tuberculosis	Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase)	0.0035	0.0708	0.1271
Loa Loa (eye worm)	PAN domain-containing protein	0.0033	0.0665	0.1732
Toxoplasma gondii	hypothetical protein	0.0033	0.0665	0.0665
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0165	0.043
Toxoplasma gondii	microneme protein MIC17A	0.0033	0.0665	0.0665
Onchocerca volvulus		0.0052	0.1279	0.6577
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0046	0.1103	0.198
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0046	0.1103	0.198
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0046	0.1103	0.198
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Onchocerca volvulus		0.0033	0.0665	0.342
Toxoplasma gondii	1,3(4)-beta-glucanase	0.0033	0.0665	0.0665
Toxoplasma gondii	subtilisin SUB12	0.0033	0.0665	0.0665
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0665	0.1732
Brugia malayi	Variant SH3 domain containing protein	0.0128	0.384	1
Leishmania major	protein kinase ck2 regulatory subunit, putative	0.0072	0.1945	1
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Onchocerca volvulus		0.0033	0.0665	0.342
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0021	0.0244	0.0437
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.0005	0.0028
Toxoplasma gondii	enoyl-acyl carrier reductase ENR	0.0179	0.5572	0.5572
Echinococcus multilocularis	casein kinase ii subunit beta	0.0072	0.1945	1
Loa Loa (eye worm)	Csnk2b protein	0.0072	0.1945	0.5065
Echinococcus granulosus	Peptidase S1 S6 chymotrypsin Hap	0.0014	0.0005	0.0028
Onchocerca volvulus		0.0014	0.0005	0.0028
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0005	0.0014
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0665	0.1732
Brugia malayi	AMP-binding enzyme family protein	0.0046	0.1103	0.2873
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0005	0.0014
Brugia malayi	Protein kinase domain containing protein	0.0052	0.1279	0.3331
Plasmodium falciparum	acyl-CoA synthetase	0.0035	0.0708	0.1271
Brugia malayi	PAN domain containing protein	0.0033	0.0665	0.1732
Echinococcus multilocularis	1 phosphatidylinositol 4,5 bisphosphate	0.0019	0.0165	0.0848
Loa Loa (eye worm)	hypothetical protein	0.0046	0.1103	0.2873
Trichomonas vaginalis	protein kinase ck2-beta, putative	0.0021	0.0244	0.0437
Trypanosoma cruzi	phosphoinositide-specific phospholipase C, putative	0.0019	0.0165	0.0848
Mycobacterium ulcerans	enoyl-(acyl carrier protein) reductase	0.0179	0.5572	1
Onchocerca volvulus		0.0033	0.0665	0.342
Trypanosoma brucei	phosphoinositide-specific phospholipase C	0.0019	0.0165	0.0848
Mycobacterium ulcerans	acyl-CoA synthetase	0.0046	0.1103	0.198
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.0005	0.0028
Toxoplasma gondii	ck2 beta subunit	0.0072	0.1945	0.1945
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0021	0.0244	0.0437
Leishmania major	phosphatidylinositol-specific phospholipase-like protein	0.0018	0.013	0.0666
Brugia malayi	Phosphatidylinositol-specific phospholipase C, X domain containing protein	0.0019	0.0165	0.043
Toxoplasma gondii	phosphoinositide phospholipase PIPLC	0.0019	0.0165	0.0165
Trypanosoma cruzi	Casein kinase II subunit beta, putative	0.0072	0.1945	1
Loa Loa (eye worm)	PAN domain-containing protein	0.0033	0.0665	0.1732
Onchocerca volvulus		0.0019	0.0165	0.0848
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Mycobacterium ulcerans	fatty-acid-CoA ligase	0.0035	0.0708	0.1271
Mycobacterium ulcerans	long-chain-fatty-acid--CoA ligase	0.0046	0.1103	0.198
Loa Loa (eye worm)	trypsin family protein	0.0014	0.0005	0.0014
Brugia malayi	Phosphatidylinositol-specific phospholipase C, X domain containing protein	0.0018	0.013	0.0338
Echinococcus multilocularis	transmembrane protease serine 3	0.0014	0.0005	0.0028
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0665	0.1732
Plasmodium falciparum	phosphoinositide-specific phospholipase C	0.0018	0.013	0.0233
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Brugia malayi	Trypsin family protein	0.0014	0.0005	0.0014
Onchocerca volvulus		0.0033	0.0665	0.342
Brugia malayi	PAN domain containing protein	0.0033	0.0665	0.1732
Toxoplasma gondii	PAN domain-containing protein	0.0033	0.0665	0.0665
Mycobacterium ulcerans	hypothetical protein	0.0046	0.1103	0.198
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.0005	0.0028
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0046	0.1103	0.5672
Brugia malayi	Kringle domain containing protein	0.0052	0.1279	0.3331
Loa Loa (eye worm)	PAN domain-containing protein	0.0033	0.0665	0.1732
Echinococcus multilocularis	Peptidase S1 S6, chymotrypsin Hap	0.0014	0.0005	0.0028
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0005	0.0014
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.0021	0.0244	0.1252
Toxoplasma gondii	PAN domain-containing protein	0.0033	0.0665	0.0665
Echinococcus granulosus	1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4	0.0019	0.0165	0.0848
Echinococcus multilocularis	glycoprotein Antigen 5	0.0014	0.0005	0.0028
Echinococcus granulosus	enteropeptidase	0.0014	0.0005	0.0028
Brugia malayi	PAN domain containing protein	0.0033	0.0665	0.1732
Brugia malayi	Trypsin-like protease protein 5	0.0014	0.0005	0.0014
Onchocerca volvulus		0.0033	0.0665	0.342
Plasmodium falciparum	casein kinase II beta chain	0.0072	0.1945	0.3491
Leishmania major	phosphoinositide-specific phospholipase C, putative	0.0018	0.013	0.0666
Onchocerca volvulus		0.0033	0.0665	0.342
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0021	0.0244	0.0437
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.0072	0.1945	1
Giardia lamblia	Casein kinase II beta chain	0.0072	0.1945	1
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.0005	0.0028
Onchocerca volvulus		0.0033	0.0665	0.342
Toxoplasma gondii	PAN domain-containing protein	0.0311	1	1
Onchocerca volvulus		0.0014	0.0005	0.0028
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0033	0.0645	0.1157
Brugia malayi	hypothetical protein	0.0014	0.0005	0.0014
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Echinococcus granulosus	transmembrane protease serine 3	0.0014	0.0005	0.0028
Onchocerca volvulus	Casein kinase II subunit beta homolog	0.0072	0.1945	1
Echinococcus multilocularis	enteropeptidase	0.0014	0.0005	0.0028
Plasmodium vivax	phospholipase C-like, putative	0.0018	0.013	0.0233
Trypanosoma brucei	Casein kinase II subunit beta, putative	0.0072	0.1945	1
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0665	0.1732
Onchocerca volvulus		0.0033	0.0665	0.342
Onchocerca volvulus		0.0033	0.0665	0.342
Loa Loa (eye worm)	PAN domain-containing protein	0.0033	0.0665	0.1732
Brugia malayi	PAN domain containing protein	0.0033	0.0665	0.1732
Mycobacterium leprae	NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE)	0.0179	0.5572	1
Loa Loa (eye worm)	TK/ROR protein kinase	0.0052	0.1279	0.3331
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0005	0.0014
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.0005	0.0028
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.0021	0.0244	0.1252
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0708	0.1845
Echinococcus granulosus	tissue type plasminogen activator	0.0052	0.1279	0.6577
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.0005	0.0028
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0021	0.0244	0.0437
Trypanosoma cruzi	hypothetical protein, conserved	0.0052	0.1279	0.6577
Chlamydia trachomatis	enoyl-acyl-carrier protein reductase	0.0179	0.5572	1
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Echinococcus granulosus	glycoprotein Antigen 5	0.0014	0.0005	0.0028
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.0005	0.0028
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Loa Loa (eye worm)	phosphatidylinositol-specific phospholipase C	0.0019	0.0165	0.043
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0708	0.1845
Mycobacterium tuberculosis	Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase)	0.0046	0.1103	0.198
Mycobacterium ulcerans	acyl-CoA synthetase	0.0046	0.1103	0.198
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0033	0.0645	0.1157
Echinococcus granulosus	casein kinase ii subunit beta	0.0072	0.1945	1
Toxoplasma gondii	PAN domain-containing protein	0.0033	0.0665	0.0665
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.0005	0.0028
Schistosoma mansoni	hypothetical protein	0.0014	0.0005	0.0028
Schistosoma mansoni	phospholipase C beta	0.0018	0.013	0.0666
Toxoplasma gondii	hypothetical protein	0.0033	0.0665	0.0665
Loa Loa (eye worm)	hypothetical protein	0.0018	0.013	0.0338
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.0072	0.1945	1
Toxoplasma gondii	microneme protein MIC4	0.0033	0.0665	0.0665
Plasmodium vivax	cysteine repeat modular protein 1, putative	0.0052	0.1279	0.2296
Mycobacterium ulcerans	hypothetical protein	0.0014	0.0005	0.001
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.0005	0.0028
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0021	0.0244	0.0437
Toxoplasma gondii	microneme protein MIC17B	0.0033	0.0665	0.0665
Trypanosoma cruzi	Casein kinase II subunit beta, putative	0.0072	0.1945	1
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.0005	0.0028
Onchocerca volvulus		0.0014	0.0005	0.0028
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0021	0.0244	0.0437
Echinococcus multilocularis	Mastin	0.0014	0.0005	0.0028
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Loa Loa (eye worm)	hypothetical protein	0.0052	0.1279	0.3331
Plasmodium vivax	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.0005	0.0028
Mycobacterium ulcerans	long-chain fatty-acid CoA ligase	0.0046	0.1103	0.198
Brugia malayi	1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4	0.0018	0.013	0.0338
Plasmodium falciparum	enoyl-acyl carrier reductase	0.0179	0.5572	1
Entamoeba histolytica	acyl-CoA synthetase, putative	0.0046	0.1103	0.5672
Onchocerca volvulus		0.0033	0.0665	0.342
Mycobacterium leprae	PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE)	0.0046	0.1103	0.198
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Brugia malayi	PAN domain containing protein	0.0033	0.0665	0.1732
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0033	0.0645	0.1157
Schistosoma mansoni	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.0005	0.0028
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Loa Loa (eye worm)	casein kinase II	0.0021	0.0244	0.0634
Entamoeba histolytica	casein kinase II regulatory subunit family protein	0.0072	0.1945	1
Mycobacterium tuberculosis	NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase)	0.0179	0.5572	1
Echinococcus multilocularis	subfamily S1A unassigned peptidase (S01 family)	0.0014	0.0005	0.0028
Trichomonas vaginalis	hypothetical protein	0.0179	0.5572	1
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0708	0.1845
Echinococcus granulosus	subfamily S1A unassigned peptidase S01 family	0.0014	0.0005	0.0028
Leishmania major	4-coumarate:coa ligase-like protein	0.0046	0.1103	0.5672
Entamoeba histolytica	acyl-coA synthetase, putative	0.0046	0.1103	0.5672
Toxoplasma gondii	microneme protein, putative	0.0033	0.0665	0.0665
Brugia malayi	Trypsin family protein	0.0014	0.0005	0.0014
Mycobacterium ulcerans	long-chain-fatty-acid-CoA ligase	0.0046	0.1103	0.198
Brugia malayi	Csnk2b protein	0.0072	0.1945	0.5065
Toxoplasma gondii	PAN/Apple domain-containing protein	0.0033	0.0665	0.0665
Onchocerca volvulus		0.0046	0.1103	0.5672
Onchocerca volvulus	Casein kinase II subunit beta homolog	0.0072	0.1945	1
Brugia malayi	Trypsin family protein	0.0014	0.0005	0.0014
Loa Loa (eye worm)	Plcb4 protein	0.0018	0.013	0.0338
Schistosoma mansoni	aminopeptidase PILS (M01 family)	0.0014	0.0005	0.0028
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0665	0.1732
Wolbachia endosymbiont of Brugia malayi	enoyl-ACP reductase	0.0179	0.5572	0.5
Plasmodium vivax	acyl-CoA synthetase, putative	0.0035	0.0708	0.1271
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0072	0.1945	0.3491
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0021	0.0244	0.0437
Mycobacterium tuberculosis	Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase)	0.0033	0.0645	0.1157
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0021	0.0244	0.0437
Onchocerca volvulus		0.0014	0.0005	0.0028
Toxoplasma gondii	kringle domain-containing protein	0.0052	0.1279	0.1279
Trichomonas vaginalis	casein kinase II beta chain, putative	0.0021	0.0244	0.0437
Brugia malayi	PAN domain containing protein	0.0033	0.0665	0.1732
Mycobacterium ulcerans	acyl-CoA synthetase	0.0046	0.1103	0.198
Onchocerca volvulus		0.0019	0.0165	0.0848
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0708	0.1845
Loa Loa (eye worm)	hypothetical protein	0.0019	0.0165	0.043
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0665	0.1732
Brugia malayi	PAN domain containing protein	0.0033	0.0665	0.1732
Onchocerca volvulus		0.0014	0.0005	0.0028
Toxoplasma gondii	PAN domain-containing protein	0.0033	0.0665	0.0665
Brugia malayi	PAN domain containing protein	0.0033	0.0665	0.1732
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0005	0.0014
Brugia malayi	PAN domain containing protein	0.0033	0.0665	0.1732
Brugia malayi	AMP-binding enzyme family protein	0.0046	0.1103	0.2873
Trichomonas vaginalis	protein kinase ck2-beta, putative	0.0021	0.0244	0.0437
Brugia malayi	PAN domain containing protein	0.0033	0.0665	0.1732
Leishmania major	4-coumarate:coa ligase-like protein	0.0046	0.1103	0.5672
Schistosoma mansoni	hypothetical protein	0.0052	0.1279	0.6577
Schistosoma mansoni	cercarial elastase (S01 family)	0.0014	0.0005	0.0028
Leishmania major	phospholipase c-like protein	0.0019	0.0165	0.0848
Echinococcus multilocularis	tissue type plasminogen activator	0.0052	0.1279	0.6577
Onchocerca volvulus		0.0033	0.0665	0.342
Plasmodium falciparum	casein kinase II beta chain	0.0072	0.1945	0.3491
Loa Loa (eye worm)	hypothetical protein	0.0033	0.0665	0.1732
Brugia malayi	AMP-binding enzyme family protein	0.0046	0.1103	0.2873
Loa Loa (eye worm)	hypothetical protein	0.0035	0.0708	0.1845
Loa Loa (eye worm)	hypothetical protein	0.0014	0.0005	0.0014
Plasmodium vivax	casein kinase II beta chain, putative	0.0072	0.1945	0.3491

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Search by Saint Jude

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.

Detailed information for compound 797583