Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Toxoplasma gondii | PAN domain-containing protein | 0.0035 | 0.0672 | 0.0672 |
Trypanosoma cruzi | Casein kinase II subunit beta, putative | 0.0074 | 0.1926 | 1 |
Toxoplasma gondii | 1,3(4)-beta-glucanase | 0.0035 | 0.0672 | 0.0672 |
Giardia lamblia | Casein kinase II beta chain | 0.0074 | 0.1926 | 1 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0012 | 0.0064 |
Toxoplasma gondii | PAN domain-containing protein | 0.0035 | 0.0672 | 0.0672 |
Onchocerca volvulus | 0.002 | 0.0172 | 0.0892 | |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.108 | 0.1997 |
Onchocerca volvulus | 0.0035 | 0.0672 | 0.3487 | |
Schistosoma mansoni | casein kinase II beta subunit | 0.0074 | 0.1926 | 1 |
Onchocerca volvulus | 0.0035 | 0.0672 | 0.3487 | |
Loa Loa (eye worm) | hypothetical protein | 0.0018 | 0.0136 | 0.0355 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Mycobacterium tuberculosis | Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) | 0.0048 | 0.108 | 0.0951 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Entamoeba histolytica | casein kinase II regulatory subunit family protein | 0.0074 | 0.1926 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0012 | 0.0032 |
Toxoplasma gondii | PAN domain-containing protein | 0.0035 | 0.0672 | 0.0672 |
Echinococcus multilocularis | glycoprotein Antigen 5 | 0.0015 | 0.0012 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.108 | 0.281 |
Echinococcus granulosus | Mastin | 0.0015 | 0.0012 | 0.0064 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Wolbachia endosymbiont of Brugia malayi | enoyl-ACP reductase | 0.0182 | 0.5359 | 0.5 |
Mycobacterium leprae | NADH-DEPENDENT ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE INHA (NADH-DEPENDENT ENOYL-ACP REDUCTASE) | 0.0182 | 0.5359 | 1 |
Toxoplasma gondii | enoyl-acyl carrier reductase ENR | 0.0182 | 0.5359 | 0.5359 |
Mycobacterium ulcerans | enoyl-(acyl carrier protein) reductase | 0.0182 | 0.5359 | 1 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0672 | 0.1747 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0672 | 0.1747 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0012 | 0.0032 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0672 | 0.1747 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Onchocerca volvulus | 0.0035 | 0.0672 | 0.3487 | |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0672 | 0.1747 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.108 | 0.281 |
Brugia malayi | Variant SH3 domain containing protein | 0.0134 | 0.3844 | 1 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0048 | 0.108 | 0.1997 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Brugia malayi | Phosphatidylinositol-specific phospholipase C, X domain containing protein | 0.002 | 0.0172 | 0.0447 |
Onchocerca volvulus | 0.0035 | 0.0672 | 0.3487 | |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.108 | 0.5273 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.108 | 0.1997 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0012 | 0.0032 |
Onchocerca volvulus | 0.0015 | 0.0012 | 0.0064 | |
Onchocerca volvulus | 0.0048 | 0.108 | 0.5608 | |
Mycobacterium tuberculosis | Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) | 0.0036 | 0.0693 | 0.0132 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Echinococcus granulosus | casein kinase ii subunit beta | 0.0074 | 0.1926 | 1 |
Schistosoma mansoni | aminopeptidase PILS (M01 family) | 0.0015 | 0.0012 | 0.0064 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.108 | 0.4973 |
Brugia malayi | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 4 | 0.0018 | 0.0136 | 0.0355 |
Onchocerca volvulus | 0.0015 | 0.0012 | 0.0064 | |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.108 | 0.5273 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0012 | 0.0032 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.108 | 0.281 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.108 | 0.281 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0672 | 0.1747 |
Mycobacterium ulcerans | hypothetical protein | 0.0048 | 0.108 | 0.1997 |
Toxoplasma gondii | ck2 beta subunit | 0.0074 | 0.1926 | 0.1926 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Toxoplasma gondii | kringle domain-containing protein | 0.0054 | 0.1285 | 0.1285 |
Loa Loa (eye worm) | trypsin family protein | 0.0015 | 0.0012 | 0.0032 |
Brugia malayi | Trypsin family protein | 0.0015 | 0.0012 | 0.0032 |
Echinococcus multilocularis | subfamily S1A unassigned peptidase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Onchocerca volvulus | 0.0054 | 0.1285 | 0.6672 | |
Schistosoma mansoni | phospholipase C beta | 0.0018 | 0.0136 | 0.0708 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Entamoeba histolytica | acyl-coA synthetase, putative | 0.0048 | 0.108 | 0.4973 |
Toxoplasma gondii | PAN/Apple domain-containing protein | 0.0035 | 0.0672 | 0.0672 |
Toxoplasma gondii | casein kinase ii regulatory subunit protein | 0.0074 | 0.1926 | 0.1926 |
Echinococcus multilocularis | 1 phosphatidylinositol 4,5 bisphosphate | 0.002 | 0.0172 | 0.0892 |
Onchocerca volvulus | 0.0015 | 0.0012 | 0.0064 | |
Echinococcus granulosus | glycoprotein Antigen 5 | 0.0015 | 0.0012 | 0.0064 |
Mycobacterium ulcerans | fatty-acid-CoA ligase | 0.0036 | 0.0693 | 0.1273 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0012 | 0.0032 |
Schistosoma mansoni | hypothetical protein | 0.0054 | 0.1285 | 0.6672 |
Onchocerca volvulus | Casein kinase II subunit beta homolog | 0.0074 | 0.1926 | 1 |
Loa Loa (eye worm) | TK/ROR protein kinase | 0.0054 | 0.1285 | 0.3343 |
Onchocerca volvulus | 0.0035 | 0.0672 | 0.3487 | |
Plasmodium vivax | cysteine repeat modular protein 1, putative | 0.0054 | 0.1285 | 0.22 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Chlamydia trachomatis | enoyl-acyl-carrier protein reductase | 0.0182 | 0.5359 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0693 | 0.1803 |
Onchocerca volvulus | Casein kinase II subunit beta homolog | 0.0074 | 0.1926 | 1 |
Leishmania major | hypothetical protein, conserved | 0.0054 | 0.1285 | 0.6419 |
Plasmodium vivax | enoyl-acyl carrier protein reductase | 0.0182 | 0.5359 | 1 |
Onchocerca volvulus | 0.002 | 0.0172 | 0.0892 | |
Trichomonas vaginalis | hypothetical protein | 0.0182 | 0.5359 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0693 | 0.1803 |
Entamoeba histolytica | casein kinase II regulatory subunit family protein | 0.0074 | 0.1926 | 1 |
Loa Loa (eye worm) | variant SH3 domain-containing protein | 0.0134 | 0.3844 | 1 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0672 | 0.1747 |
Toxoplasma gondii | PAN domain-containing protein | 0.0035 | 0.0672 | 0.0672 |
Loa Loa (eye worm) | hypothetical protein | 0.0048 | 0.108 | 0.281 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0672 | 0.1747 |
Echinococcus granulosus | 1-Phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-4 | 0.002 | 0.0172 | 0.0892 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Toxoplasma gondii | microneme protein MIC17A | 0.0035 | 0.0672 | 0.0672 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Plasmodium falciparum | casein kinase II beta chain | 0.0074 | 0.1926 | 0.3427 |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0172 | 0.0447 |
Mycobacterium tuberculosis | Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) | 0.0048 | 0.108 | 0.0951 |
Entamoeba histolytica | acyl-CoA synthetase, putative | 0.0048 | 0.108 | 0.4973 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Toxoplasma gondii | hypothetical protein | 0.0035 | 0.0672 | 0.0672 |
Toxoplasma gondii | PAN domain-containing protein | 0.0327 | 1 | 1 |
Leishmania major | 4-coumarate:coa ligase-like protein | 0.0048 | 0.108 | 0.5273 |
Echinococcus granulosus | enteropeptidase | 0.0015 | 0.0012 | 0.0064 |
Brugia malayi | Trypsin family protein | 0.0015 | 0.0012 | 0.0032 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Mycobacterium ulcerans | long-chain fatty-acid CoA ligase | 0.0048 | 0.108 | 0.1997 |
Brugia malayi | Csnk2b protein | 0.0074 | 0.1926 | 0.5011 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0672 | 0.1747 |
Onchocerca volvulus | 0.0035 | 0.0672 | 0.3487 | |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0693 | 0.1803 |
Onchocerca volvulus | 0.0035 | 0.0672 | 0.3487 | |
Plasmodium vivax | acyl-CoA synthetase, putative | 0.0036 | 0.0693 | 0.1066 |
Onchocerca volvulus | 0.0035 | 0.0672 | 0.3487 | |
Brugia malayi | Trypsin family protein | 0.0015 | 0.0012 | 0.0032 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0672 | 0.1747 |
Loa Loa (eye worm) | Plcb4 protein | 0.0018 | 0.0136 | 0.0355 |
Onchocerca volvulus | 0.0035 | 0.0672 | 0.3487 | |
Loa Loa (eye worm) | hypothetical protein | 0.002 | 0.0172 | 0.0447 |
Brugia malayi | Trypsin family protein | 0.0015 | 0.0012 | 0.0032 |
Echinococcus granulosus | tissue type plasminogen activator | 0.0054 | 0.1285 | 0.6672 |
Toxoplasma gondii | microneme protein, putative | 0.0035 | 0.0672 | 0.0672 |
Echinococcus granulosus | Peptidase S1 S6 chymotrypsin Hap | 0.0015 | 0.0012 | 0.0064 |
Plasmodium falciparum | enoyl-acyl carrier reductase | 0.0182 | 0.5359 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0672 | 0.1747 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Echinococcus multilocularis | casein kinase ii subunit beta | 0.0074 | 0.1926 | 1 |
Toxoplasma gondii | phosphoinositide phospholipase PIPLC | 0.002 | 0.0172 | 0.0172 |
Onchocerca volvulus | 0.0015 | 0.0012 | 0.0064 | |
Echinococcus granulosus | transmembrane protease serine 3 | 0.0015 | 0.0012 | 0.0064 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0012 | 0.0032 |
Plasmodium falciparum | casein kinase II beta chain | 0.0074 | 0.1926 | 0.3427 |
Echinococcus multilocularis | tissue type plasminogen activator | 0.0054 | 0.1285 | 0.6672 |
Brugia malayi | casein kinase II, putaitve | 0.0022 | 0.0243 | 0.0633 |
Echinococcus multilocularis | transmembrane protease serine 3 | 0.0015 | 0.0012 | 0.0064 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0693 | 0.1803 |
Loa Loa (eye worm) | hypothetical protein | 0.0035 | 0.0672 | 0.1747 |
Toxoplasma gondii | microneme protein MIC17C | 0.0035 | 0.0672 | 0.0672 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0035 | 0.0672 | 0.1747 |
Brugia malayi | Trypsin-like protease protein 5 | 0.0015 | 0.0012 | 0.0032 |
Loa Loa (eye worm) | Csnk2b protein | 0.0074 | 0.1926 | 0.5011 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0693 | 0.1803 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0035 | 0.0672 | 0.1747 |
Toxoplasma gondii | microneme protein MIC4 | 0.0035 | 0.0672 | 0.0672 |
Brugia malayi | Phosphatidylinositol-specific phospholipase C, X domain containing protein | 0.0018 | 0.0136 | 0.0355 |
Toxoplasma gondii | subtilisin SUB12 | 0.0035 | 0.0672 | 0.0672 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0035 | 0.0672 | 0.1747 |
Toxoplasma gondii | microneme protein MIC17B | 0.0035 | 0.0672 | 0.0672 |
Schistosoma mansoni | hypothetical protein | 0.0015 | 0.0012 | 0.0064 |
Plasmodium falciparum | acyl-CoA synthetase | 0.0036 | 0.0693 | 0.1066 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0672 | 0.1747 |
Brugia malayi | Kringle domain containing protein | 0.0054 | 0.1285 | 0.3343 |
Echinococcus granulosus | subfamily S1A unassigned peptidase S01 family | 0.0015 | 0.0012 | 0.0064 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Schistosoma mansoni | subfamily S1A unassigned peptidase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Onchocerca volvulus | 0.0035 | 0.0672 | 0.3487 | |
Entamoeba histolytica | casein kinase II regulatory subunit family protein | 0.0074 | 0.1926 | 1 |
Toxoplasma gondii | hypothetical protein | 0.0035 | 0.0672 | 0.0672 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Brugia malayi | Protein kinase domain containing protein | 0.0054 | 0.1285 | 0.3343 |
Trypanosoma brucei | Casein kinase II subunit beta, putative | 0.0074 | 0.1926 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0054 | 0.1285 | 0.3343 |
Loa Loa (eye worm) | phosphatidylinositol-specific phospholipase C | 0.002 | 0.0172 | 0.0447 |
Plasmodium vivax | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.3427 |
Brugia malayi | hypothetical protein | 0.0015 | 0.0012 | 0.0032 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0672 | 0.1747 |
Loa Loa (eye worm) | casein kinase II | 0.0022 | 0.0243 | 0.0633 |
Trypanosoma cruzi | Casein kinase II subunit beta, putative | 0.0074 | 0.1926 | 1 |
Leishmania major | protein kinase ck2 regulatory subunit, putative | 0.0074 | 0.1926 | 1 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Leishmania major | phospholipase c-like protein | 0.002 | 0.0172 | 0.0198 |
Echinococcus multilocularis | enteropeptidase | 0.0015 | 0.0012 | 0.0064 |
Plasmodium falciparum | cysteine repeat modular protein 1 | 0.0054 | 0.1285 | 0.22 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0672 | 0.1747 |
Echinococcus multilocularis | Peptidase S1 S6, chymotrypsin Hap | 0.0015 | 0.0012 | 0.0064 |
Mycobacterium tuberculosis | NADH-dependent enoyl-[acyl-carrier-protein] reductase InhA (NADH-dependent enoyl-ACP reductase) | 0.0182 | 0.5359 | 1 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0054 | 0.1285 | 0.6347 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0035 | 0.0672 | 0.1747 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0672 | 0.1747 |
Onchocerca volvulus | 0.0015 | 0.0012 | 0.0064 | |
Onchocerca volvulus | 0.0015 | 0.0012 | 0.0064 | |
Loa Loa (eye worm) | hypothetical protein | 0.0015 | 0.0012 | 0.0032 |
Schistosoma mansoni | cercarial elastase (S01 family) | 0.0015 | 0.0012 | 0.0064 |
Loa Loa (eye worm) | PAN domain-containing protein | 0.0035 | 0.0672 | 0.1747 |
Mycobacterium ulcerans | long-chain-fatty-acid-CoA ligase | 0.0048 | 0.108 | 0.1997 |
Mycobacterium ulcerans | long-chain-fatty-acid--CoA ligase | 0.0048 | 0.108 | 0.1997 |
Echinococcus multilocularis | Mastin | 0.0015 | 0.0012 | 0.0064 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0672 | 0.1747 |
Trichomonas vaginalis | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.329 |
Onchocerca volvulus | 0.0035 | 0.0672 | 0.3487 | |
Plasmodium vivax | casein kinase II beta chain, putative | 0.0074 | 0.1926 | 0.3427 |
Brugia malayi | PAN domain containing protein | 0.0035 | 0.0672 | 0.1747 |
Brugia malayi | AMP-binding enzyme family protein | 0.0048 | 0.108 | 0.281 |
Mycobacterium ulcerans | acyl-CoA synthetase | 0.0048 | 0.108 | 0.1997 |
Brugia malayi | Chymotrypsin-like protease CTRL-1 precursor | 0.0015 | 0.0012 | 0.0032 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.