Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0215 | 0.0422 | 1 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0198 | 0.0227 | 0.5 |
Onchocerca volvulus | 0.0178 | 0 | 0.5 | |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.1052 | 1 | 1 |
Echinococcus granulosus | acetylcholinesterase | 0.1052 | 1 | 1 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0198 | 0.0227 | 0.0227 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0198 | 0.0227 | 1 |
Brugia malayi | Methionine aminopeptidase protein type I | 0.0215 | 0.0422 | 0.0422 |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0198 | 0.0227 | 0.0227 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0198 | 0.0227 | 1 |
Trypanosoma brucei | methionine aminopeptidase, type I, putative | 0.0215 | 0.0422 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0198 | 0.0227 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1052 | 1 | 1 |
Onchocerca volvulus | 0.0178 | 0 | 0.5 | |
Trypanosoma brucei | methionine aminopeptidase, putative | 0.0215 | 0.0422 | 0.5 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0198 | 0.0227 | 0.5 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0198 | 0.0227 | 1 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0215 | 0.0422 | 0.5 |
Echinococcus multilocularis | methionyl aminopeptidase 1 (M24 family) | 0.0215 | 0.0422 | 0.0422 |
Onchocerca volvulus | 0.0178 | 0 | 0.5 | |
Echinococcus granulosus | methionyl aminopeptidase 1 M24 family | 0.0215 | 0.0422 | 0.0422 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0215 | 0.0422 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.1052 | 1 | 1 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0198 | 0.0227 | 0.5 |
Trichomonas vaginalis | carboxylesterase domain containing protein, putative | 0.0178 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.1052 | 1 | 1 |
Onchocerca volvulus | 0.0178 | 0 | 0.5 | |
Schistosoma mansoni | methionyl aminopeptidase 1 (M24 family) | 0.0198 | 0.0227 | 0.0227 |
Loa Loa (eye worm) | methionine aminopeptidase type I | 0.0215 | 0.0422 | 0.0422 |
Echinococcus multilocularis | acetylcholinesterase | 0.1052 | 1 | 1 |
Leishmania major | methionine aminopeptidase, putative,metallo-peptidase, Clan MG, Family M24 | 0.0215 | 0.0422 | 0.5 |
Trypanosoma brucei | metallo- peptidase, Clan MG, Family M24 | 0.0215 | 0.0422 | 0.5 |
Trichomonas vaginalis | spcc417.12 protein, putative | 0.0178 | 0 | 0.5 |
Onchocerca volvulus | 0.0178 | 0 | 0.5 | |
Echinococcus multilocularis | carboxylesterase 5A | 0.1052 | 1 | 1 |
Loa Loa (eye worm) | carboxylesterase | 0.1052 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.1052 | 1 | 1 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.1052 | 1 | 1 |
Trypanosoma cruzi | metallo- peptidase, Clan MG, Family M24 | 0.0215 | 0.0422 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.1052 | 1 | 1 |
Toxoplasma gondii | methionine aminopeptidase | 0.0215 | 0.0422 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.1052 | 1 | 1 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0198 | 0.0227 | 0.5 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0198 | 0.0227 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.