Detailed information for compound 79910

Basic information

Technical information
  • TDR Targets ID: 79910
  • Name: 1,3-dibenzyl-1-[3-[benzyl(benzylcarbamoyl)ami no]-2-hydroxypropyl]urea
  • MW: 536.664 | Formula: C33H36N4O3
  • H donors: 3 H acceptors: 3 LogP: 4.24 Rotable bonds: 16
    Rule of 5 violations (Lipinski): 2
  • SMILES: OC(CN(C(=O)NCc1ccccc1)Cc1ccccc1)CN(C(=O)NCc1ccccc1)Cc1ccccc1
  • InChi: 1S/C33H36N4O3/c38-31(25-36(23-29-17-9-3-10-18-29)32(39)34-21-27-13-5-1-6-14-27)26-37(24-30-19-11-4-12-20-30)33(40)35-22-28-15-7-2-8-16-28/h1-20,31,38H,21-26H2,(H,34,39)(H,35,40)
  • InChiKey: GDCRZMOHWNRLPA-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1,3-dibenzyl-1-[3-[benzyl(benzylcarbamoyl)amino]-2-hydroxy-propyl]urea
  • 1,3-dibenzyl-1-[3-[benzyl-[(benzylamino)-oxomethyl]amino]-2-hydroxypropyl]urea
  • 1-[2-hydroxy-3-[phenylmethyl(phenylmethylcarbamoyl)amino]propyl]-1,3-bis(phenylmethyl)urea
  • 1-[2-hydroxy-3-(phenylmethyl-(phenylmethylcarbamoyl)amino)propyl]-1,3-bis(phenylmethyl)urea
  • 1-[2-hydroxy-3-[[oxo-(phenylmethylamino)methyl]-(phenylmethyl)amino]propyl]-1,3-bis(phenylmethyl)urea
  • 1,3-bis(benzyl)-1-[3-(benzyl-(benzylcarbamoyl)amino)-2-hydroxy-propyl]urea
  • AIDS-006542
  • AIDS006542
  • N,N-(2-Hydroxy-1,3-propanediyl)bis(N,N'-dibenzylurea)

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0143 0.0586 0.5874
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0036 0.0098 0.0247
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0146 0.0604 0.1517
Treponema pallidum UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2206 1 1
Plasmodium falciparum glutathione reductase 0.0053 0.0176 0.2803
Echinococcus multilocularis dna polymerase eta 0.0171 0.0717 0.18
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.087 0.3431
Loa Loa (eye worm) RecQ helicase 0.0045 0.0143 0.0562
Echinococcus multilocularis calcium transporting atpase 0.0101 0.0396 0.0993
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.0191 0.0479
Loa Loa (eye worm) hypothetical protein 0.0232 0.0994 0.3919
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0093 0.0359 0.5012
Echinococcus multilocularis cathepsin b 0.0018 0.0019 0.0048
Brugia malayi Type III restriction enzyme, res subunit family protein 0.0034 0.0091 0.041
Loa Loa (eye worm) glutathione reductase 0.0152 0.063 0.2483
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Wolbachia endosymbiont of Brugia malayi UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2206 1 1
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.0191 0.3158
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Trypanosoma cruzi P-type H+-ATPase, putative 0.0036 0.0101 0.0172
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0176 0.2462
Onchocerca volvulus 0.0056 0.0191 0.1825
Schistosoma mansoni smad1 5 8 and 0.0026 0.0057 0.0142
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0046 0.0147 0.243
Loa Loa (eye worm) MH2 domain-containing protein 0.0026 0.0057 0.0223
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0019 0.0304
Entamoeba histolytica hypothetical protein 0.0018 0.0019 0.0317
Brugia malayi Protein cec-1. 0.0034 0.0091 0.041
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0234 0.1004 0.396
Mycobacterium ulcerans DNA polymerase IV 0.0143 0.0586 0.0586
Toxoplasma gondii E1-E2 ATPase subfamily protein 0.0036 0.0101 0.0364
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0101 0.0173
Trypanosoma brucei DNA polymerase IV, putative 0.0136 0.0557 0.7769
Trypanosoma cruzi calcium-transporting ATPase, putative 0.004 0.0117 0.02
Plasmodium falciparum serine repeat antigen 5 0.0018 0.0019 0.0304
Giardia lamblia Cysteine protease 0.0018 0.0019 0.0075
Plasmodium falciparum copper-transporting ATPase 0.0026 0.0055 0.0878
Brugia malayi calcium ATPase 0.004 0.0119 0.0538
Trichomonas vaginalis MYB3r3, putative 0.0061 0.0214 0.2143
Echinococcus multilocularis cathepsin L cysteine protease 0.0056 0.0191 0.0479
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0024 0.0388
Echinococcus multilocularis copper transporting ATPase 1 0.0026 0.0055 0.0139
Brugia malayi Cytochrome P450 family protein 0.0016 0.0007 0.0032
Plasmodium falciparum conserved Plasmodium protein, unknown function 0.0034 0.0091 0.1443
Schistosoma mansoni DNA polymerase eta 0.0171 0.0717 0.18
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0023 0.0041 0.0147
Trypanosoma cruzi trypanothione reductase, putative 0.0053 0.0176 0.0301
Echinococcus multilocularis Smad4 0.0026 0.0057 0.0142
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0019 0.0192
Brugia malayi MH2 domain containing protein 0.0387 0.1702 0.767
Trypanosoma cruzi cysteine peptidase, putative 0.1298 0.5856 1
Echinococcus multilocularis nuclear factor of activated T cells 5 0.0072 0.0266 0.0667
Loa Loa (eye worm) hypothetical protein 0.0046 0.0147 0.0579
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Loa Loa (eye worm) hypothetical protein 0.0034 0.0091 0.0358
Brugia malayi Sodium/potassium-transporting ATPase alpha-3 chain, putative 0.0036 0.0101 0.0455
Onchocerca volvulus 0.0122 0.0493 0.4715
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0448
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Brugia malayi haloacid dehalogenase-like hydrolase family protein 0.0047 0.0149 0.067
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0056 0.0564
Schistosoma mansoni cpg binding protein 0.0028 0.0065 0.0162
Plasmodium vivax phosphodiesterase gamma, putative 0.0069 0.0253 0.4012
Echinococcus granulosus chromodomain helicase DNA binding protein 1 0.0034 0.0091 0.0228
Brugia malayi CHE-14 protein 0.0041 0.0125 0.0564
Loa Loa (eye worm) helicase 0.0034 0.0091 0.0358
Echinococcus multilocularis ankyrin repeat and death domain containing protein 0.0014 0.0001 0.0001
Brugia malayi MH1 domain containing protein 0.0015 0.0003 0.0012
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0023 0.0041 0.0057
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0023 0.0041 0.0147
Giardia lamblia Cathepsin L precursor 0.0018 0.0019 0.0075
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Echinococcus multilocularis phospholipid transporting ATPase IIB 0.0026 0.0055 0.0139
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0139
Trypanosoma brucei hypothetical protein, conserved 0.0069 0.0253 0.3524
Brugia malayi MH1 domain containing protein 0.0026 0.0057 0.0255
Echinococcus multilocularis lamin 0.0026 0.0057 0.0143
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0019 0.0021 0.0084
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0245 0.0615
Brugia malayi Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0101 0.0396 0.1783
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0019 0.0086
Schistosoma mansoni lamin 0.0026 0.0057 0.0143
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.012 0.1202
Schistosoma mansoni hypothetical protein 0.004 0.0118 0.0297
Trypanosoma brucei calcium motive p-type ATPase, putative 0.0066 0.0238 0.332
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0055 0.0246
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.01 0.0394 0.099
Trichomonas vaginalis DNA helicase recq, putative 0.0045 0.0143 0.1427
Entamoeba histolytica plasma membrane calcium-transporting ATPase, putative 0.002 0.0026 0.0428
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0612 0.1044
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0214 0.2143
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0046 0.0648
Brugia malayi hypothetical protein 0.0232 0.0994 0.4478
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Brugia malayi cathepsin F-like cysteine proteinase 0.0022 0.0035 0.0159
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0015 0.0004 0.0016
Loa Loa (eye worm) cysteine protease 0.0056 0.0191 0.0752
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.012 0.1202
Schistosoma mansoni ATPase 0.0117 0.0471 0.1182
Entamoeba histolytica hypothetical protein 0.0146 0.0604 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0055 0.0215
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0064 0.0227 0.057
Loa Loa (eye worm) MH2 domain-containing protein 0.0387 0.1702 0.6713
Loa Loa (eye worm) hypothetical protein 0.0139 0.057 0.225
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0053 0.0176 0.0795
Trypanosoma cruzi cysteine peptidase, putative 0.0056 0.0191 0.0326
Chlamydia trachomatis phosphoshikimate 1-carboxyl vinyltransferase 0.0622 0.2773 0.2773
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0098 0.0981
Echinococcus granulosus dna polymerase kappa 0.0143 0.0586 0.1472
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0019 0.0192
Mycobacterium tuberculosis Possible metal cation transporting P-type ATPase CtpH 0.0056 0.0192 0.0269
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Trichomonas vaginalis cation-transporting ATPase, putative 0.0026 0.0055 0.0553
Trichomonas vaginalis C-MYB, putative 0.0061 0.0214 0.2143
Brugia malayi cathepsin B-like cysteine proteinase 0.0018 0.0019 0.0086
Loa Loa (eye worm) hypothetical protein 0.0311 0.1355 0.5344
Plasmodium vivax cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.4012
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0053 0.0176 0.2803
Trichomonas vaginalis C-MYB, putative 0.0061 0.0214 0.2143
Schistosoma mansoni phosphoserine phosphatase 0.0017 0.0012 0.0029
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0118 0.1956
Brugia malayi MAP kinase sur-1 0.005 0.0164 0.074
Leishmania major target of rapamycin (TOR) kinase 1, putative 0.0044 0.0137 0.1914
Brugia malayi MH2 domain containing protein 0.0026 0.0057 0.0255
Loa Loa (eye worm) cytochrome P450 family protein 0.0026 0.0053 0.021
Trypanosoma brucei cAMP-specific phosphodiesterase, putative 0.0069 0.0253 0.3524
Schistosoma mansoni atpase class VI type 11c 0.0017 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0089 0.0342 0.135
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0214 0.3541
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.057 0.2535 1
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0092 0.0919
Echinococcus granulosus cation transporting atpase worm 0.0026 0.0055 0.0139
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0665 0.2622
Onchocerca volvulus 0.0026 0.0055 0.0522
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0019 0.0033
Plasmodium vivax unspecified product 0.004 0.0118 0.1877
Echinococcus multilocularis phosphatidylinositol 3 and 4 kinase 0.0015 0.0004 0.0009
Loa Loa (eye worm) hypothetical protein 0.0056 0.0191 0.0752
Echinococcus multilocularis tar DNA binding protein 0.0068 0.0245 0.0615
Mycobacterium leprae conserved hypothetical protein 0.0023 0.0041 0.0057
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Echinococcus multilocularis dna polymerase kappa 0.0143 0.0586 0.1472
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.012 0.1202
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0056 0.0191 0.0752
Plasmodium vivax copper-transporting ATPase, putative 0.0026 0.0055 0.0878
Schistosoma mansoni smad 0.0026 0.0057 0.0142
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.01 0.0394 0.099
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0098 0.0246
Schistosoma mansoni cpg binding protein 0.003 0.0072 0.0181
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0019 0.0192
Entamoeba histolytica deoxycytidyl transferase, putative 0.0116 0.0468 0.7739
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0037 0.0104 0.1045
Brugia malayi Associated with TFs and helicases family protein 0.0034 0.0091 0.041
Schistosoma mansoni DNA polymerase IV / kappa 0.0036 0.0101 0.0254
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.2462
Echinococcus multilocularis high affinity cAMP specific 3',5' cyclic 0.0069 0.0253 0.0634
Toxoplasma gondii cation-transporting atpase family protein 0.0017 0.0012 0.0042
Leishmania major cAMP-specific phosphodiesterase, putative 0.0069 0.0253 0.3524
Brugia malayi MH1 domain containing protein 0.0026 0.0057 0.0255
Trypanosoma brucei phosphatidylinositol 3-kinase, putative 0.0015 0.0004 0.0051
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Echinococcus multilocularis survival motor neuron protein 1 0.0232 0.0994 0.2495
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.5947
Leishmania major cathepsin L-like protease 0.0148 0.0612 0.8532
Schistosoma mansoni cathepsin B (C01 family) 0.0018 0.0019 0.0048
Plasmodium vivax serine-repeat antigen 2 (SERA) 0.0018 0.0019 0.0304
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0026 0.0055 0.0199
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.005 0.0164 0.2289
Schistosoma mansoni lipoxygenase 0.0054 0.0183 0.046
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Echinococcus granulosus netrin receptor unc 5 0.0014 0.0001 0.0001
Echinococcus multilocularis mitogen activated protein kinase 0.005 0.0164 0.0412
Plasmodium falciparum chromodomain-helicase-DNA-binding protein 1 homolog, putative 0.0034 0.0091 0.1443
Schistosoma mansoni camp/cgmp cyclic nucleotide phosphodiesterase 0.0069 0.0253 0.0634
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0039 0.0113 0.0508
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0347 0.1518 0.2119
Loa Loa (eye worm) hypothetical protein 0.003 0.0073 0.0289
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0019 0.0192
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0019 0.0192
Echinococcus multilocularis expressed conserved protein 0.0091 0.035 0.0878
Onchocerca volvulus 0.0056 0.0191 0.1825
Loa Loa (eye worm) hypothetical protein 0.0034 0.0092 0.0362
Schistosoma mansoni cpg binding protein 0.003 0.0072 0.0181
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Echinococcus granulosus Smad4 0.0026 0.0057 0.0142
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0098 0.0981
Schistosoma mansoni dipeptidyl-peptidase I (C01 family) 0.0018 0.0019 0.0048
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor1 0.0044 0.0137 0.0234
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0053 0.0176 0.0246
Echinococcus multilocularis bloom syndrome protein 0.0045 0.0143 0.0358
Echinococcus granulosus geminin 0.0887 0.3983 1
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Trichomonas vaginalis PIKK family atypical protein kinase 0.0038 0.0108 0.108
Leishmania major cathepsin L-like protease 0.0056 0.0191 0.2661
Trypanosoma brucei P-type H+-ATPase, putative 0.0053 0.0176 0.2458
Plasmodium falciparum serine repeat antigen 3 0.0018 0.0019 0.0304
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Loa Loa (eye worm) hypothetical protein 0.012 0.0484 0.1909
Trypanosoma brucei unspecified product 0.008 0.0303 0.4222
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Trypanosoma brucei vacuolar-type Ca2+-ATPase 1 0.0093 0.0359 0.5012
Echinococcus granulosus smad 0.0026 0.0057 0.0142
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0021 0.0077
Brugia malayi Valyl-tRNA synthetase 0.0034 0.0091 0.041
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0066 0.0238 0.0939
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0116 0.0468 0.1174
Onchocerca volvulus 0.0092 0.0358 0.3422
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0152 0.0685
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0053 0.0176 0.0443
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0253 0.0431
Brugia malayi Cathepsin L-like precursor 0.0034 0.0092 0.0413
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.05 0.2219 1
Schistosoma mansoni cathepsin S (C01 family) 0.0018 0.0019 0.0048
Echinococcus granulosus high affinity cgmp specific 3' 5' cyclic 0.0069 0.0253 0.0634
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0448
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0253 0.0431
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0021 0.0077
Plasmodium vivax DNA repair protein REV1, putative 0.0036 0.0101 0.1606
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0007 0.0012
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Onchocerca volvulus Cathepsin L homolog 0.0056 0.0191 0.1825
Trypanosoma cruzi DNA polymerase kappa, putative 0.0143 0.0586 0.1001
Loa Loa (eye worm) hypothetical protein 0.0051 0.0168 0.0661
Leishmania major trypanothione reductase 0.0152 0.063 0.8782
Toxoplasma gondii thioredoxin reductase 0.0152 0.063 0.227
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0024 0.0061
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Trypanosoma cruzi DNA damage repair protein, putative 0.0036 0.0101 0.0173
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0056 0.0191 0.303
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0053 0.0176 0.0176
Loa Loa (eye worm) hypothetical protein 0.0083 0.0313 0.1236
Plasmodium falciparum phosphodiesterase delta, putative 0.0069 0.0253 0.4012
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0215 0.2156
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Echinococcus multilocularis musashi 0.0026 0.0057 0.0143
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0218
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.0332 0.4633
Loa Loa (eye worm) hypothetical protein 0.0122 0.0493 0.1944
Loa Loa (eye worm) hypothetical protein 0.0062 0.022 0.0868
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0101 0.0396 0.0993
Leishmania major P-type H -ATPase, putative 0.0053 0.0176 0.2458
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0069 0.0253 0.0431
Trypanosoma cruzi cAMP-specific phosphodiesterase, putative 0.0069 0.0253 0.0431
Plasmodium vivax SET domain protein, putative 0.003 0.0073 0.1152
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0004 0.0036
Giardia lamblia DNA damage repair protein 0.0036 0.0101 0.0399
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0053 0.0176 0.2803
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0098 0.0981
Trypanosoma brucei chrX additional, unordered contigs 0.0036 0.0101 0.1411
Leishmania major P-type H -ATPase, putative 0.0053 0.0176 0.2458
Brugia malayi Immunoglobulin I-set domain containing protein 0.0014 0.0001 0.0002
Echinococcus multilocularis Na+:K+ ATPase alpha subunit 0.0066 0.0238 0.0598
Toxoplasma gondii cathepsin CPL 0.0056 0.0191 0.0688
Echinococcus granulosus intermediate filament protein 0.0026 0.0057 0.0143
Onchocerca volvulus 0.0082 0.0308 0.2947
Brugia malayi Phosphatidylinositol 3- and 4-kinase family protein 0.0044 0.0137 0.0618
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0069 0.0253 0.0431
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0962
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0098 0.0981
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0019 0.0075
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0101 0.1411
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0214 0.2143
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0073 0.0262
Onchocerca volvulus 0.0026 0.0057 0.0544
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0056 0.0191 0.303
Schistosoma mansoni chromobox protein 0.0034 0.0091 0.0228
Plasmodium falciparum phosphodiesterase gamma, putative 0.0069 0.0253 0.4012
Schistosoma mansoni hypothetical protein 0.004 0.0118 0.0297
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Echinococcus multilocularis cathepsin b 0.0018 0.0019 0.0048
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0069 0.0253 0.0634
Trypanosoma cruzi cAMP phosphodiesterase A, putative 0.0069 0.0253 0.0431
Brugia malayi Bloom's syndrome protein homolog 0.0045 0.0143 0.0642
Echinococcus multilocularis Chromobox protein 3 0.0034 0.0091 0.0228
Leishmania major proton motive ATPase, putative 0.0026 0.0055 0.0771
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Schistosoma mansoni chromobox protein 0.015 0.0621 0.1558
Plasmodium falciparum DNA repair protein REV1, putative 0.0036 0.0101 0.1606
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0118 0.1956
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0053 0.0176 0.2803
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Toxoplasma gondii sarco/endoplasmic reticulum Ca2+-ATPase 0.0117 0.0471 0.1698
Loa Loa (eye worm) hypothetical protein 0.0032 0.0084 0.0331
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0019 0.0075
Toxoplasma gondii heavy metal translocating P-type ATPase subfamily protein 0.0026 0.0055 0.0199
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0447
Echinococcus granulosus cathepsin l1 0.0034 0.0092 0.023
Echinococcus multilocularis high affinity cgmp specific 3' 5' cyclic 0.0069 0.0253 0.0634
Brugia malayi CXXC zinc finger family protein 0.0028 0.0065 0.0291
Schistosoma mansoni cathepsin s 0.0022 0.0035 0.0088
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0019 0.0048
Loa Loa (eye worm) hypothetical protein 0.0061 0.0215 0.0847
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0019 0.0192
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0036 0.0098 0.0247
Brugia malayi M-phase phosphoprotein, mpp8 0.0122 0.0493 0.2221
Leishmania major DNA polymerase eta, putative 0.0171 0.0717 1
Onchocerca volvulus Huntingtin homolog 0.012 0.0484 0.4632
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Mycobacterium leprae PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB 0.0026 0.0055 0.0077
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.3599
Loa Loa (eye worm) heterochromatin protein 1 0.015 0.0621 0.2448
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0098 0.0981
Schistosoma mansoni hypothetical protein 0.0032 0.0084 0.0211
Entamoeba histolytica plasma membrane calcium-transporting ATPase 1, putative 0.0057 0.0195 0.3221
Schistosoma mansoni hypothetical protein 0.0023 0.004 0.0102
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0118 0.0297
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0098 0.0167
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0126 0.0513 0.0875
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Toxoplasma gondii LsmAD domain-containing protein 0.0051 0.0169 0.0608
Trypanosoma cruzi cruzipain precursor, putative 0.1298 0.5856 1
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.0191 0.0479
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0026 0.0055 0.0094
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0394 0.099
Giardia lamblia Potassium-transporting ATPase alpha chain 1 0.0066 0.0238 0.0939
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.05 0.2219 0.8752
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.005 0.0164 0.0647
Toxoplasma gondii cathepsin CPC1 0.0018 0.0019 0.0069
Trichomonas vaginalis pc-MYB2, putative 0.0061 0.0214 0.2143
Brugia malayi Cathepsin L-like precursor 0.0022 0.0035 0.0159
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0019 0.0192
Echinococcus multilocularis dual 3',5' cyclic AMP and GMP phosphodiesterase 0.0069 0.0253 0.0634
Trichomonas vaginalis cation-transporting ATPase, putative 0.0117 0.0471 0.4717
Trichomonas vaginalis Clan CA, family C1, cathepsin F-like cysteine peptidase 0.0018 0.0019 0.0192
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Onchocerca volvulus 0.0056 0.0191 0.1825
Echinococcus multilocularis protein dispatched 1 0.0047 0.0152 0.0381
Plasmodium vivax serine-repeat antigen 3 (SERA) 0.0018 0.0019 0.0304
Giardia lamblia hypothetical protein 0.0069 0.0253 0.0996
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0069 0.0253 0.0634
Treponema pallidum NADH oxidase 0.0053 0.0176 0.0176
Schistosoma mansoni transcription factor LCR-F1 0.0146 0.0604 0.1517
Trichomonas vaginalis cAMP/cGMP cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Loa Loa (eye worm) hypothetical protein 0.005 0.0163 0.0643
Toxoplasma gondii histone lysine methyltransferase SET1 0.0054 0.0184 0.0665
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0019 0.0021 0.034
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0019 0.0192
Loa Loa (eye worm) Na,K-ATPase alpha subunit 0.0083 0.0313 0.1236
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0055 0.0215
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0055 0.0914
Echinococcus granulosus FKBP12 rapamycin complex associated protein 0.0044 0.0137 0.0344
Echinococcus multilocularis FKBP12 rapamycin complex associated protein 0.0044 0.0137 0.0344
Schistosoma mansoni cathepsin F (C01 family) 0.0056 0.0191 0.0479
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Echinococcus multilocularis mitogen activated protein kinase 3 0.005 0.0164 0.0412
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0253 0.0431
Leishmania major phosphopantetheinyl transferase-like protein 0.0023 0.0041 0.0569
Echinococcus multilocularis cation transporting ATPase 13A1 0.0026 0.0055 0.0139
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Schistosoma mansoni hypothetical protein 0.0019 0.0024 0.0061
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0665 0.1669
Toxoplasma gondii preprocathepsin c precursor, putative 0.0018 0.0019 0.0069
Brugia malayi Cathepsin L-like precursor 0.0056 0.0191 0.086
Schistosoma mansoni hypothetical protein 0.0887 0.3983 1
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0394 0.099
Treponema pallidum 4'-phosphopantetheinyl transferase 0.0023 0.0041 0.0041
Toxoplasma gondii cathepsin CPC2 0.0018 0.0019 0.0069
Loa Loa (eye worm) hypothetical protein 0.0019 0.0024 0.0096
Mycobacterium ulcerans metal cation transporter p-type ATPase a 0.0083 0.0313 0.0313
Echinococcus granulosus neuropeptide s receptor 0.046 0.2033 0.5103
Entamoeba histolytica cysteine protease, putative 0.0018 0.0019 0.0317
Echinococcus granulosus L aminoadipate semialdehyde 0.0082 0.0308 0.0773
Loa Loa (eye worm) hypothetical protein 0.0102 0.0403 0.1591
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0065 0.0231 0.0394
Trypanosoma brucei DNA damage repair protein, putative 0.0036 0.0101 0.1411
Mycobacterium ulcerans cation transporter p-type ATPase a CtpA 0.0026 0.0055 0.0055
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Entamoeba histolytica recQ family helicase, putative 0.0024 0.0046 0.0769
Schistosoma mansoni Na+/K+ transporting ATPase subunit alpha 0.0083 0.0313 0.0787
Trypanosoma brucei DNA damage repair protein, putative 0.0036 0.0101 0.1411
Schistosoma mansoni cation-transporting ATPase 0.0026 0.0055 0.0139
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Schistosoma mansoni retinoblastoma-binding protein 4 (rbbp4) 0.0014 0.0001 0.0003
Trichomonas vaginalis Clan CA, family C1, cathepsin L, S or H-like cysteine peptidase 0.0018 0.0019 0.0192
Mycobacterium leprae PROBABLE CATION-TRANSPORTER ATPASE I CTPI 0.0056 0.0192 0.0269
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.2462
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0176 0.0301
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0055 0.0215
Trypanosoma cruzi major cysteine proteinase, putative 0.011 0.044 0.0751
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0245 0.0615
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0073 0.0182
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.012 0.1202
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0026 0.0057 0.0142
Brugia malayi MH2 domain containing protein 0.0026 0.0057 0.0255
Toxoplasma gondii target of rapamycin (TOR), putative 0.0033 0.0086 0.0309
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Brugia malayi cahepsin L-like non-peptiedase homolog 0.0018 0.0019 0.0086
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Mycobacterium ulcerans metal cation-transporting p-type ATPase CtpC 0.0026 0.0055 0.0055
Leishmania major cathepsin L-like protease 0.0148 0.0612 0.8532
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0118 0.1183
Loa Loa (eye worm) latrophilin receptor protein 2 0.0032 0.0084 0.0331
Trichomonas vaginalis glutathione reductase, putative 0.0053 0.0176 0.1768
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Echinococcus multilocularis sarco:endoplasmic reticulum calcium ATPase 0.0117 0.0471 0.1182
Plasmodium vivax vivapain-1 0.004 0.0118 0.1877
Echinococcus granulosus Chromo domain 0.0034 0.0091 0.0228
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.0332 0.4633
Echinococcus granulosus RUN 0.0019 0.0024 0.0061
Plasmodium vivax P-type ATPase4, putative 0.0117 0.0471 0.748
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.0091 0.0328
Echinococcus granulosus cathepsin b 0.0018 0.0019 0.0048
Brugia malayi hypothetical protein 0.0019 0.0024 0.011
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0019 0.0086
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0024 0.0061
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0053 0.0176 0.0443
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0164 0.028
Onchocerca volvulus Chorion peroxidase homolog 0.0026 0.0055 0.0522
Trypanosoma brucei unspecified product 0.008 0.0303 0.4222
Trypanosoma brucei phosphatidylinositol 3-kinase tor, putative 0.0021 0.0031 0.0436
Echinococcus multilocularis RUN 0.0019 0.0024 0.0061
Trypanosoma cruzi P-type H+-ATPase, putative 0.0053 0.0176 0.0301
Loa Loa (eye worm) transcription factor SMAD2 0.0387 0.1702 0.6713
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0019 0.0304
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.05 0.2219 0.5571
Echinococcus granulosus chromobox protein 1 0.015 0.0621 0.1558
Brugia malayi Doublecortin family protein 0.0019 0.0024 0.011
Schistosoma mansoni cgmp-dependent 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Onchocerca volvulus Netrin receptor homolog 0.0014 0.0001 0.0005
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0069 0.0253 0.253
Plasmodium falciparum calcium-transporting ATPase 0.0101 0.0396 0.6284
Trypanosoma brucei Phosphatidylinositol 3-kinase tor1 0.0044 0.0137 0.1914
Toxoplasma gondii 'chromo' (CHRromatin Organization MOdifier) domain-containing protein 0.0034 0.0091 0.0328
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0098 0.0981
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0022 0.0035 0.0139
Plasmodium falciparum serine repeat antigen 7 0.0018 0.0019 0.0304
Loa Loa (eye worm) hypothetical protein 0.0034 0.0091 0.0358
Trypanosoma cruzi plasma-membrane proton-efflux P-type ATPase, putative 0.0036 0.0101 0.0172
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.057 0.2535 0.6366
Trypanosoma brucei DNA polymerase kappa, putative 0.0123 0.0497 0.6933
Brugia malayi Smad1 0.0026 0.0057 0.0255
Echinococcus multilocularis dnaJ subfamily B 0.0401 0.1765 0.4433
Loa Loa (eye worm) hypothetical protein 0.0051 0.0169 0.0665
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0118 0.0297
Plasmodium vivax unspecified product 0.0022 0.0035 0.056
Schistosoma mansoni copper ABC transporter ATPase 0.0026 0.0055 0.0139
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Brugia malayi cathepsin L precursor 0.0018 0.0019 0.0086
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Schistosoma mansoni chromobox protein 0.0034 0.0091 0.0228
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.005 0.0164 0.0592
Trichomonas vaginalis mercuric reductase, putative 0.0053 0.0176 0.1768
Mycobacterium leprae Probable metal cation-transporting P-type ATPase C CtpC 0.0026 0.0055 0.0077
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0036 0.0098 0.0247
Echinococcus multilocularis GPCR, family 2 0.0032 0.0084 0.0211
Trypanosoma brucei phosphatidylinositol 4-kinase, putative 0.0044 0.0137 0.1914
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma brucei calcium-translocating P-type ATPase 0.0101 0.0396 0.5519
Echinococcus multilocularis microtubule associated protein 2 0.0677 0.3022 0.7588
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Plasmodium vivax vivapain-3 0.004 0.0118 0.1877
Echinococcus granulosus phosphatidylinositol 3 and 4 kinase 0.0015 0.0004 0.0009
Plasmodium vivax dipeptidyl aminopeptidase 3, putative 0.0018 0.0019 0.0304
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0002
Onchocerca volvulus Peroxidase homolog 0.0026 0.0055 0.0522
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0056 0.0191 0.0752
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0069 0.0253 0.1138
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0098 0.0386
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0091 0.091
Echinococcus multilocularis cathepsin L 0.0018 0.0019 0.0048
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Echinococcus granulosus chromobox protein 2 0.0034 0.0091 0.0228
Onchocerca volvulus 0.0233 0.0999 0.9557
Echinococcus multilocularis plasma membrane calcium transporting ATPase 0.0076 0.0284 0.0713
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.022 0.3069
Loa Loa (eye worm) hypothetical protein 0.0041 0.0125 0.0494
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0394 0.099
Entamoeba histolytica cysteine proteinase, putative 0.0034 0.0092 0.1519
Loa Loa (eye worm) thioredoxin reductase 0.0152 0.063 0.2483
Loa Loa (eye worm) hypothetical protein 0.0069 0.0253 0.0996
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0245 0.0615
Entamoeba histolytica hypothetical protein 0.0034 0.0091 0.1504
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.0301
Schistosoma mansoni alpha-glucosidase 0.0137 0.0563 0.1414
Onchocerca volvulus Cathepsin L homolog 0.0056 0.0191 0.1825
Trichomonas vaginalis ATPase, class I, type 8B, putative 0.0026 0.0055 0.0553
Trichomonas vaginalis conserved hypothetical protein 0.0041 0.0125 0.1254
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0019 0.0021 0.0054
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0024 0.0061
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0612 0.1044
Brugia malayi hypothetical protein 0.0017 0.0012 0.0052
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0169 0.2677
Echinococcus multilocularis tumor protein p63 0.0331 0.1447 0.3634
Echinococcus granulosus peroxidasin 0.0026 0.0055 0.0137
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Echinococcus granulosus TGF beta signal transducer SmadC 0.0026 0.0057 0.0142
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0118 0.1648
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0055 0.0246
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Loa Loa (eye worm) Smad1 0.0026 0.0057 0.0223
Giardia lamblia Cathepsin L precursor 0.0018 0.0019 0.0075
Plasmodium falciparum serine repeat antigen 4 0.0018 0.0019 0.0304
Brugia malayi Blistered cuticle protein 3 0.0026 0.0055 0.0246
Trypanosoma brucei protein kinase, putative 0.005 0.0164 0.2289
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0118 0.0532
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Schistosoma mansoni survival motor neuron protein 0.0047 0.0152 0.0381
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Brugia malayi Niemann-Pick C1 protein precursor 0.0097 0.0376 0.1697
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0164 0.1644
Trypanosoma brucei cAMP phosphodiesterase A, putative 0.0069 0.0253 0.3524
Mycobacterium ulcerans cation-transporter ATPase I CtpI 0.0056 0.0192 0.0192
Giardia lamblia Copper-transporting P-type ATPase 0.0026 0.0055 0.0218
Plasmodium vivax heterochromatin protein 1, putative 0.0034 0.0091 0.1443
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0118 0.0202
Schistosoma mansoni type V p-type atpase isoform 0.0026 0.0055 0.0139
Plasmodium falciparum dipeptidyl aminopeptidase 2 0.0018 0.0019 0.0304
Brugia malayi Cathepsin L-like precursor 0.0056 0.0191 0.086
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0091 0.1443
Giardia lamblia Cysteine protease 0.0018 0.0019 0.0075
Brugia malayi glutathione reductase 0.0152 0.063 0.2837
Plasmodium vivax ataxin-2 like protein, putative 0.0051 0.0169 0.2677
Giardia lamblia NADH oxidase lateral transfer candidate 0.0053 0.0176 0.0696
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0069 0.0253 0.0431
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0053 0.0176 0.0301
Trypanosoma brucei target of rapamycin kinase 3, putative 0.0035 0.0096 0.1343
Trypanosoma cruzi cysteine peptidase C (CPC), putative 0.0018 0.0019 0.0033
Mycobacterium tuberculosis Probable oxidoreductase 0.0385 0.1694 0.2365
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0098 0.0981
Schistosoma mansoni calcium-transporting atpase 2 (atpase 2) 0.0101 0.0396 0.0993
Onchocerca volvulus 0.0243 0.1045 1
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0102 0.0403 0.1818
Plasmodium falciparum thioredoxin reductase 0.0053 0.0176 0.2803
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0055 0.0914
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0139
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0118 0.1956
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.05 0.2219 0.5571
Schistosoma mansoni cathepsin C 0.0018 0.0019 0.0048
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0069 0.0253 0.4012
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.3599
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0218
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.004 0.0118 0.0297
Echinococcus granulosus nuclear factor of activated T cells 5 0.0072 0.0266 0.0667
Giardia lamblia Hypothetical protein 0.0018 0.0019 0.0075
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0073 0.0182
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Onchocerca volvulus 0.0047 0.0152 0.1453
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0053 0.0176 0.0443
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0043 0.0131 0.0471
Toxoplasma gondii haloacid dehalogenase family hydrolase domain-containing protein 0.0017 0.0012 0.0042
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0123 0.0497 0.0694
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0347 0.1518 0.2119
Leishmania major cytochrome p450-like protein 0.0016 0.0007 0.0098
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0076 0.0284 0.0713
Brugia malayi hypothetical protein 0.012 0.0484 0.2182
Brugia malayi SET domain containing protein 0.0036 0.0099 0.0444
Brugia malayi cathepsin Z-like cysteine proteinase 0.0018 0.0019 0.0086
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Loa Loa (eye worm) hypothetical protein 0.003 0.0073 0.0286
Trichomonas vaginalis MYB72, putative 0.0061 0.0214 0.2143
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0098 0.0383 0.0962
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0041 0.0648
Brugia malayi Peroxidasin 0.0026 0.0055 0.0246
Echinococcus granulosus cpg binding protein 0.003 0.0072 0.0181
Echinococcus granulosus expressed conserved protein 0.0091 0.035 0.0878
Echinococcus multilocularis chromodomain helicase DNA binding protein 1 0.0034 0.0091 0.0228
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0034 0.0092 0.0919
Brugia malayi hypothetical protein 0.0146 0.0604 0.2723
Loa Loa (eye worm) hypothetical protein 0.0034 0.0091 0.0358
Trichomonas vaginalis MYB, putative 0.0061 0.0215 0.2156
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Echinococcus granulosus cathepsin L cysteine proteinase 0.0056 0.0191 0.0479
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.4012
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Brugia malayi potential phospholipid-transporting ATPase IIB, putative 0.0026 0.0055 0.0249
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.005 0.0164 0.2289
Loa Loa (eye worm) CXXC zinc finger family protein 0.0028 0.0065 0.0255
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.0332 0.4633
Trypanosoma cruzi cysteine peptidase, putative 0.004 0.0118 0.0202
Echinococcus granulosus survival motor neuron protein 1 0.0232 0.0994 0.2495
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0089 0.0342 0.3274
Brugia malayi RNA binding protein 0.0068 0.0245 0.1104
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Echinococcus multilocularis calcium transporting ATPase type 2C member 0.0117 0.0471 0.1182
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.012 0.1202
Echinococcus multilocularis calcium:calmodulin dependent 3',5' cyclic 0.0069 0.0253 0.0634
Schistosoma mansoni plasma membrane calcium-transporting atpase 0.0076 0.0284 0.0713
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.0301
Plasmodium vivax vivapain-2 0.0056 0.0191 0.303
Brugia malayi Probable 3',5'-cyclic phosphodiesterase C32E12.2, putative 0.0069 0.0253 0.1138
Giardia lamblia Cysteine protease 0.0018 0.0019 0.0075
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0069 0.0253 0.1138
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0014 0.0001 0.0003
Trypanosoma cruzi DNA polymerase eta, putative 0.0171 0.0717 0.1224
Echinococcus multilocularis X box binding protein 1 0.0282 0.1225 0.3075
Mycobacterium ulcerans cation transporter p-type ATPase D CtpD 0.0026 0.0055 0.0055
Mycobacterium tuberculosis Probable reductase 0.0347 0.1518 0.2119
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase A CtpF 0.0035 0.0094 0.0131
Giardia lamblia Phospholipid-transporting ATPase IA, putative 0.0026 0.0055 0.0218
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0073 0.0182
Loa Loa (eye worm) hypothetical protein 0.0027 0.0057 0.0226
Leishmania major cAMP phosphodiesterase A, putative;with=GeneDB:LinJ18_V3.1100 0.0069 0.0253 0.3524
Entamoeba histolytica hypothetical protein 0.0034 0.0091 0.1504
Toxoplasma gondii plasma membrane-type Ca(2+)-ATPase A1 PMCAA1 0.0076 0.0284 0.1024
Schistosoma mansoni hypothetical protein 0.0032 0.0084 0.0211
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0116 0.0468 0.1174
Schistosoma mansoni cellular tumor antigen P53 0.0048 0.0157 0.0395
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Onchocerca volvulus 0.0018 0.0019 0.0183
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0253 0.0431
Brugia malayi Latrophilin receptor protein 2 0.0032 0.0084 0.0379
Echinococcus granulosus cysteine protease 0.004 0.0118 0.0297
Giardia lamblia Myb 1-like protein 0.0061 0.0215 0.0849
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0347 0.1518 0.2119
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0152 0.063 0.0879
Trypanosoma cruzi target of rapamycin kinase 3 0.0035 0.0096 0.0164
Brugia malayi hypothetical protein 0.0026 0.0055 0.0246
Plasmodium falciparum cysteine proteinase falcipain 1 0.004 0.0118 0.1877
Mycobacterium ulcerans 3-phosphoshikimate 1-carboxyvinyltransferase 0.0622 0.2773 0.2773
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Entamoeba histolytica cysteine protease, putative 0.0018 0.0019 0.0317
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.005 0.0164 0.028
Loa Loa (eye worm) hypothetical protein 0.0015 0.0003 0.0011
Schistosoma mansoni hypothetical protein 0.0887 0.3983 1
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0019 0.0192
Schistosoma mansoni serine/threonine protein kinase 0.005 0.0164 0.0412
Leishmania major P-type ATPase, putative 0.0076 0.0284 0.3961
Trichomonas vaginalis pc-MYB2, putative 0.0061 0.0214 0.2143
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.057 0.2535 0.6366
Loa Loa (eye worm) hypothetical protein 0.0019 0.0024 0.0096
Plasmodium falciparum serine repeat antigen 9 0.0018 0.0019 0.0304
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Trypanosoma brucei unspecified product 0.0136 0.0557 0.7769
Echinococcus granulosus cation transporting ATPase 13A3 0.0026 0.0055 0.0139
Trypanosoma cruzi DNA polymerase kappa, putative 0.0143 0.0586 0.1001
Loa Loa (eye worm) hypothetical protein 0.0082 0.0308 0.1215
Echinococcus granulosus mothers against decapentaplegic 5 0.0026 0.0057 0.0142
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0214 0.2143
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0095 0.0369 0.3532
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Schistosoma mansoni hypothetical protein 0.004 0.0118 0.0297
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0218
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0253 0.0431
Entamoeba histolytica cysteine protease, putative 0.0056 0.0191 0.3158
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0091 0.1504
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0098 0.0441
Entamoeba histolytica hypothetical protein 0.0146 0.0604 1
Toxoplasma gondii cathepsin B 0.0018 0.0019 0.0069
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Schistosoma mansoni peroxidasin 0.0026 0.0055 0.0137
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0091 0.035 0.1264
Plasmodium vivax dipeptidyl aminopeptidase 2, putative 0.0018 0.0019 0.0304
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0023 0.0041 0.0041
Echinococcus granulosus Chromobox protein 3 0.0034 0.0091 0.0228
Loa Loa (eye worm) cysteine proteinase cathepsin Z 0.0018 0.0019 0.0075
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0073 0.0182
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Schistosoma mansoni chromobox protein 0.015 0.0621 0.1558
Echinococcus multilocularis chromobox protein 2 0.0034 0.0091 0.0228
Trypanosoma cruzi phospholipid-transporting ATPase-like protein, putative 0.0017 0.0012 0.002
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Giardia lamblia Plasma membrane calcium-transporting ATPase 2 0.0093 0.0359 0.1417
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0102 0.0403 0.1591
Echinococcus granulosus dual 3'5' cyclic AMP and GMP phosphodiesterase 0.0069 0.0253 0.0634
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0097 0.0376 0.6232
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0026 0.0057 0.0224
Brugia malayi calcium ATPase 0.0036 0.0101 0.0455
Plasmodium vivax unspecified product 0.0018 0.0019 0.0304
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Echinococcus multilocularis mothers against decapentaplegic 5 0.0026 0.0057 0.0142
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0093 0.0359 0.0613
Trypanosoma brucei calcium-transporting ATPase, putative 0.004 0.0117 0.1633
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.0214 0.0536
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0106 0.1067
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0024 0.0061
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0116 0.0468 0.1844
Schistosoma mansoni hypothetical protein 0.004 0.0118 0.0297
Schistosoma mansoni subfamily C1A unassigned peptidase (C01 family) 0.0018 0.0019 0.0048
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Schistosoma mansoni hypothetical protein 0.0401 0.1765 0.4433
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.4012
Loa Loa (eye worm) hypothetical protein 0.0122 0.0493 0.1946
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0183 0.046
Brugia malayi Pre-SET motif family protein 0.0205 0.087 0.392
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Toxoplasma gondii chromodomain helicase DNA binding protein CHD1/SWI2/SNF2 0.0034 0.0091 0.0328
Onchocerca volvulus 0.0048 0.0157 0.1506
Echinococcus multilocularis netrin receptor unc 5 0.0014 0.0001 0.0001
Onchocerca volvulus 0.0064 0.0227 0.2173
Loa Loa (eye worm) immunoglobulin I-set domain-containing protein 0.0014 0.0001 0.0002
Brugia malayi Probable cation-transporting ATPase C10C6.6 in chromosome IV 0.0026 0.0055 0.0249
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Brugia malayi Cathepsin L-like precursor 0.0056 0.0191 0.086
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.057 0.2535 0.6366
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.057 0.2535 0.6366
Brugia malayi Pax transcription factor protein 2 0.0243 0.1045 0.471
Trichomonas vaginalis chromobox protein, putative 0.015 0.0621 0.6216
Onchocerca volvulus 0.0026 0.0057 0.0544
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0245 0.0615
Trichomonas vaginalis DNA helicase recq1, putative 0.0045 0.0143 0.1427
Plasmodium vivax cation transporting ATPase, putative 0.0026 0.0055 0.0878
Loa Loa (eye worm) hypothetical protein 0.0026 0.0057 0.0224
Entamoeba histolytica hypothetical protein 0.0146 0.0604 1
Treponema pallidum hypothetical protein 0.0017 0.0012 0.0012
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0069 0.0253 0.0431
Echinococcus granulosus dna polymerase eta 0.0171 0.0717 0.18
Echinococcus granulosus Ankyrin 0.0014 0.0001 0.0003
Schistosoma mansoni cation-transporting atpase 13a1 (G-box binding protein) 0.0026 0.0055 0.0139
Brugia malayi cathepsin L-like cysteine proteinase, identical 0.0022 0.0035 0.0159
Schistosoma mansoni patched 1 0.0041 0.0125 0.0314
Schistosoma mansoni intermediate filament proteins 0.0026 0.0057 0.0143
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0017 0.0012 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0091 0.091
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0164 0.1644
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0019 0.0021 0.0054
Leishmania major cathepsin L-like protease 0.0056 0.0191 0.2661
Brugia malayi Membrane calcium atpase protein 3 0.0076 0.0284 0.128
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0032 0.0084 0.0211
Giardia lamblia Cathepsin B-like cysteine proteinase 3 precursor 0.0018 0.0019 0.0075
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.3599
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0007 0.0028
Plasmodium falciparum thioredoxin reductase 0.0152 0.063 1
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0021 0.0096
Echinococcus granulosus cathepsin l cysteine peptidase 0.0056 0.0191 0.0479
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.3524
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0385 0.1694 0.2365
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0082 0.0308 0.0773
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0019 0.0086
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma brucei trypanothione reductase 0.0152 0.063 0.8782
Loa Loa (eye worm) CYP4Cod1 0.0016 0.0007 0.0028
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0137 0.1374
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0188 0.1879
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Toxoplasma gondii calcium-translocating P-type ATPase, PMCA-type protein 0.0093 0.0359 0.1295
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0012 0.0042
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0342 0.3428
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0031 0.0076 0.1203
Schistosoma mansoni cation-transporting atpase worm 0.0026 0.0055 0.0139
Schistosoma mansoni alpha-glucosidase 0.0137 0.0563 0.1414
Loa Loa (eye worm) hypothetical protein 0.012 0.0484 0.1909
Trypanosoma cruzi cysteine protease, putative 0.004 0.0118 0.0202
Trypanosoma brucei P-type H+-ATPase, putative 0.0053 0.0176 0.2458
Trichomonas vaginalis cation-transporting ATPase fungi, putative 0.0093 0.0359 0.3599
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0023 0.004 0.0102
Loa Loa (eye worm) hypothetical protein 0.0034 0.0091 0.0358
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0101 0.0365
Echinococcus granulosus Niemann Pick C1 protein 0.0138 0.0565 0.142
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.0301
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Entamoeba histolytica FKBP-rapamycin associated protein (FRAP), putative 0.0044 0.0137 0.2271
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0019 0.0192
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0146 0.0604 0.1517
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0026 0.0057 0.0142
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Brugia malayi E1-E2 ATPase family protein 0.0053 0.0176 0.0794
Echinococcus multilocularis lamin dm0 0.0026 0.0057 0.0143
Echinococcus multilocularis Glycoside hydrolase, family 27 0.01 0.0394 0.099
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0347 0.1518 0.2119
Schistosoma mansoni camp-specific cyclic nucleotide phosphodiesterase 0.0069 0.0253 0.0634
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0962
Plasmodium falciparum heterochromatin protein 1 0.0034 0.0091 0.1443
Plasmodium falciparum ataxin-2 like protein, putative 0.0051 0.0169 0.2677
Brugia malayi Thioredoxin reductase 0.0152 0.063 0.2837
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0069 0.0253 0.3524
Trichomonas vaginalis cation-transporting ATPase, putative 0.0053 0.0176 0.1765
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0023 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.0034 0.0091 0.0358
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0447
Loa Loa (eye worm) hypothetical protein 0.0097 0.0376 0.1485
Toxoplasma gondii melibiase subfamily protein 0.01 0.0394 0.1422
Trypanosoma cruzi cysteine proteinase, putative 0.004 0.0118 0.0202
Echinococcus granulosus cathepsin L cysteine protease 0.004 0.0118 0.0297
Entamoeba histolytica hypothetical protein 0.0146 0.0604 1
Schistosoma mansoni rab6-interacting 0.0019 0.0024 0.0061
Leishmania major vacuolar-type Ca2 -ATPase, putative 0.0093 0.0359 0.5012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0137 0.1374
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0253 0.253
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0004 0.0036
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0098 0.0981
Trichomonas vaginalis PIKK family atypical protein kinase 0.0029 0.0067 0.0668
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0032 0.0084 0.0379
Brugia malayi Probable calcium-transporting ATPase KIAA0703 0.0074 0.0275 0.1238
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0215 0.2156
Trichomonas vaginalis cGMP-inhibited 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Echinococcus multilocularis cation transporting ATPase 13A3 0.0026 0.0055 0.0139
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0962
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0032 0.0084 0.0211
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0073 0.0182
Echinococcus multilocularis Niemann Pick C1 protein 0.0097 0.0376 0.0945
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Onchocerca volvulus 0.0019 0.0024 0.0233
Schistosoma mansoni na+/k+ atpase alpha subunit 0.0066 0.0238 0.0598
Loa Loa (eye worm) RNA binding protein 0.0068 0.0245 0.0967
Loa Loa (eye worm) hypothetical protein 0.057 0.2535 1
Toxoplasma gondii phospholipid-translocating P-type ATPase, flippase subfamily protein 0.0017 0.0012 0.0042
Entamoeba histolytica phosphatidylinositol3-kinaseTor2, putative 0.0044 0.0137 0.2271
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0056 0.0564
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Schistosoma mansoni peroxidasin 0.0026 0.0055 0.0137
Mycobacterium tuberculosis Probable metal cation transporter ATPase P-type CtpE 0.0026 0.0055 0.0077
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Loa Loa (eye worm) calcium ATPase 0.0057 0.0195 0.0768
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0098 0.0167
Leishmania major phosphatidylinositol 3-kinase, putative 0.0015 0.0004 0.0051
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0019 0.0086
Trichomonas vaginalis chromobox protein, putative 0.0095 0.0369 0.3698
Onchocerca volvulus 0.0056 0.0191 0.1825
Echinococcus multilocularis smad 0.0026 0.0057 0.0142
Plasmodium vivax thioredoxin reductase, putative 0.0152 0.063 1
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0019 0.0192
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0098 0.1366
Entamoeba histolytica cysteine protease, putative 0.0018 0.0019 0.0317
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0019 0.0075
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.004 0.0118 0.0202
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0004 0.0036
Leishmania major phosphatidylinositol 3-related kinase, putative 0.0015 0.0004 0.0051
Onchocerca volvulus 0.0061 0.0215 0.2053
Trichomonas vaginalis ATPase, class VI, type 11C, putative 0.0026 0.0055 0.0553
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0004 0.0036
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0448
Schistosoma mansoni DNA helicase recq1 0.0019 0.0021 0.0054
Loa Loa (eye worm) calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase 0.0069 0.0253 0.0996
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0076 0.0284 0.2844
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.0301
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0242 0.0607
Toxoplasma gondii P-type ATPase PMA1 0.0053 0.0176 0.0635
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Brugia malayi ImpB/MucB/SamB family protein 0.0171 0.0717 0.3231
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0214 0.2143
Trypanosoma brucei PAB1-binding protein , putative 0.0051 0.0169 0.2351
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Echinococcus multilocularis cathepsin L 0.004 0.0118 0.0297
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0214 0.3541
Echinococcus multilocularis peroxidasin 0.0026 0.0055 0.0137
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0053 0.0176 0.0176
Mycobacterium leprae PROBABLE UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE MURA 0.1584 0.7163 1
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Echinococcus granulosus lamin 0.0026 0.0057 0.0143
Trypanosoma brucei cytochrome P450, putative 0.0016 0.0007 0.0098
Echinococcus multilocularis geminin 0.0887 0.3983 1
Plasmodium falciparum serine repeat antigen 2 0.0018 0.0019 0.0304
Leishmania major DNA polymerase eta, putative 0.0091 0.035 0.4889
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Giardia lamblia Sgs1 DNA helicase, putative 0.0019 0.0021 0.0084
Entamoeba histolytica hypothetical protein 0.0034 0.0091 0.1504
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Giardia lamblia Kinase, CMGC MAPK 0.005 0.0164 0.0647
Schistosoma mansoni calcium/calmodulin-dependent 35-cyclic nucleotide phosphodiesterase 0.0069 0.0253 0.0634
Trypanosoma cruzi Phosphatidylinositol 3-kinase tor2 0.0044 0.0137 0.0234
Giardia lamblia Cathepsin L precursor 0.0018 0.0019 0.0075
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin H-like cysteine peptidase 0.0018 0.0019 0.0192
Loa Loa (eye worm) nuclear factor I 0.0015 0.0003 0.0011
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0098 0.1621
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0088 0.0338 0.0849
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0032 0.0084 0.0211
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.057 0.2535 0.9142
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0019 0.0183
Trichomonas vaginalis DNA polymerase eta, putative 0.0143 0.0586 0.5874
Trypanosoma cruzi copper-transporting ATPase, putative 0.0017 0.0012 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Brugia malayi TAR-binding protein 0.0068 0.0245 0.1104
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0055 0.0246
Trypanosoma brucei DNA polymerase eta, putative 0.0171 0.0717 1
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.004 0.012 0.1202
Echinococcus granulosus dnaJ subfamily B 0.0401 0.1765 0.4433
Plasmodium falciparum dipeptidyl aminopeptidase 1 0.0018 0.0019 0.0304
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0046 0.0648
Plasmodium falciparum serine repeat antigen 8 0.0018 0.0019 0.0304
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Trichomonas vaginalis cone cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Echinococcus multilocularis phospholipid transporting ATPase VA 0.0017 0.0012 0.0029
Trichomonas vaginalis hypothetical protein 0.0034 0.0091 0.091
Trichomonas vaginalis calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Echinococcus granulosus GPCR family 2 0.0032 0.0084 0.0211
Mycobacterium ulcerans DNA polymerase IV 0.0143 0.0586 0.0586
Loa Loa (eye worm) hypothetical protein 0.0034 0.0092 0.0362
Onchocerca volvulus 0.0083 0.0313 0.2998
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Echinococcus multilocularis chromobox protein 1 0.015 0.0621 0.1558
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0019 0.0075
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0069 0.0253 0.253
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0041 0.0125 0.0494
Echinococcus granulosus microtubule associated protein 2 0.0677 0.3022 0.7588
Loa Loa (eye worm) hypothetical protein 0.0034 0.0092 0.0362
Giardia lamblia Hypothetical protein 0.0069 0.0253 0.0996
Entamoeba histolytica plasma membrane calcium ion-transporting ATPase, putative 0.0057 0.0195 0.3221
Trichomonas vaginalis PIKK family atypical protein kinase 0.0015 0.0004 0.0036
Leishmania major cathepsin L-like protease 0.0148 0.0612 0.8532
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0053 0.0176 0.0176
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Loa Loa (eye worm) E1-E2 ATPase 0.0053 0.0176 0.0695
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0338 0.0849
Toxoplasma gondii P-type ATPase4, putative 0.0083 0.0313 0.113
Schistosoma mansoni polycystin 1-related 0.0019 0.0024 0.0061
Treponema pallidum cation-transporting ATPase, P-type 0.0026 0.0055 0.0055
Trichomonas vaginalis Heterochromatin protein, putative 0.0034 0.0091 0.091
Echinococcus multilocularis cysteine protease 0.0056 0.0191 0.0479
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Giardia lamblia Dipeptidyl-peptidase I precursor 0.0018 0.0019 0.0075
Trichomonas vaginalis phospholipid-transporting ATPase, putative 0.0026 0.0055 0.0553
Loa Loa (eye worm) hypothetical protein 0.0171 0.0717 0.2827
Mycobacterium ulcerans metal cation transporter ATPase p-type CtpE 0.0026 0.0055 0.0055
Echinococcus granulosus plasma membrane calcium transporting ATPase 0.0076 0.0284 0.0713
Giardia lamblia Cysteine protease 0.0018 0.0019 0.0075
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0088 0.0338 0.0849
Echinococcus granulosus mitogen activated protein kinase 0.005 0.0164 0.0412
Loa Loa (eye worm) hypothetical protein 0.0069 0.0253 0.0996
Mycobacterium tuberculosis Probable metal cation transporter P-type ATPase CtpV 0.0026 0.0055 0.0077
Echinococcus granulosus copper transporting ATPase 1 0.0026 0.0055 0.0139
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Trichomonas vaginalis chromobox protein, putative 0.015 0.0621 0.6216
Toxoplasma gondii shikimate dehydrogenase substrate binding domain-containing protein 0.0622 0.2773 1
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0019 0.0317
Trypanosoma cruzi calcium-translocating P-type ATPase, putative 0.0036 0.0101 0.0172
Entamoeba histolytica phospholipid-transporting P-type ATPase, putative 0.0026 0.0055 0.0914
Echinococcus granulosus chromobox protein 1 0.015 0.0621 0.1558
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0091 0.091
Trichomonas vaginalis high-affinity cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Onchocerca volvulus Dual oxidase homolog 0.0026 0.0055 0.0522
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.0301
Echinococcus granulosus calcium:calmodulin dependent 3'5' cyclic 0.0069 0.0253 0.0634
Giardia lamblia Cathepsin L precursor 0.0018 0.0019 0.0075
Brugia malayi Death domain containing protein 0.0014 0.0001 0.0002
Echinococcus granulosus cation transporting ATPase 13A1 0.0026 0.0055 0.0139
Schistosoma mansoni hypothetical protein 0.007 0.0256 0.0642
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0098 0.0246
Schistosoma mansoni hypothetical protein 0.0047 0.0152 0.0381
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0053 0.0176 0.0301
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Brugia malayi chromobox protein homolog 3 0.0089 0.0342 0.1542
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0065 0.0163
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.012 0.1202
Plasmodium falciparum cGMP-specific phosphodiesterase 0.0069 0.0253 0.4012
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.057 0.2535 0.6366
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0023 0.0041 0.0041
Loa Loa (eye worm) hypothetical protein 0.007 0.0256 0.1008
Toxoplasma gondii Myb family DNA-binding domain-containing protein 0.0061 0.0215 0.0776
Brugia malayi Na,K-ATPase alpha subunit 0.0083 0.0313 0.1412
Trypanosoma cruzi trypanothione reductase, putative 0.0152 0.063 0.1075
Loa Loa (eye worm) blistered cuticle protein 3 0.0026 0.0055 0.0215
Mycobacterium ulcerans UDP-N-acetylglucosamine 1-carboxyvinyltransferase 0.2206 1 1
Trypanosoma brucei hypothetical protein, conserved 0.0023 0.0041 0.0569
Schistosoma mansoni hypothetical protein 0.0032 0.0084 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0962
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0053 0.0176 0.2803
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Leishmania major cathepsin L-like protease 0.0056 0.0191 0.2661
Loa Loa (eye worm) hypothetical protein 0.0022 0.0035 0.0139
Echinococcus granulosus cathepsin L 0.004 0.0118 0.0297
Echinococcus granulosus neuropeptide receptor A26 0.046 0.2033 0.5103
Brugia malayi E1-E2 ATPase family protein 0.0026 0.0055 0.0249
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma cruzi Calcium ATPase SERCA-like 0.0117 0.0471 0.0804
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0056 0.0191 0.1911
Giardia lamblia Cathepsin L precursor 0.0018 0.0019 0.0075
Trichomonas vaginalis cAMP and cAMP-inhibited cGMP 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Brugia malayi Melibiase family protein 0.0067 0.0242 0.1089
Echinococcus multilocularis protein patched 0.0041 0.0125 0.0314
Trypanosoma cruzi cAMP specific phosphodiesterase, putative 0.0069 0.0253 0.0431
Trichomonas vaginalis chromobox protein, putative 0.0095 0.0369 0.3698
Echinococcus granulosus cathepsin b 0.0018 0.0019 0.0048
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0123 0.0497 0.6933
Trypanosoma brucei DNA polymerase IV, putative 0.0143 0.0586 0.8181
Echinococcus multilocularis Tetracycline resistance leader peptide, TetL 0.0093 0.0359 0.0902
Plasmodium falciparum cysteine proteinase falcipain 3 0.0056 0.0191 0.303
Brugia malayi Heterochromatin protein 1 0.015 0.0621 0.2796
Onchocerca volvulus 0.0034 0.0092 0.0878
Trypanosoma cruzi major cysteine proteinase, putative 0.0018 0.0019 0.0033
Loa Loa (eye worm) hypothetical protein 0.0069 0.0253 0.0996
Brugia malayi ImpB/MucB/SamB family protein 0.0116 0.0468 0.2107
Loa Loa (eye worm) hypothetical protein 0.0018 0.0019 0.0075
Echinococcus multilocularis cysteine protease 0.0056 0.0191 0.0479
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0055 0.0246
Brugia malayi Papain family cysteine protease containing protein 0.0056 0.0191 0.086
Echinococcus granulosus tumor protein p63 0.0331 0.1447 0.3634
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.004 0.0117 0.1866
Entamoeba histolytica cysteine protease, putative 0.0018 0.0019 0.0317
Schistosoma mansoni lamin 0.0026 0.0057 0.0143
Entamoeba histolytica hypothetical protein 0.0023 0.0041 0.0675
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.004 0.0118 0.1183
Trypanosoma cruzi plasma membrane Ca2+ ATPase 0.0093 0.0359 0.0613
Brugia malayi 3'5'-cyclic nucleotide phosphodiesterase family protein 0.0069 0.0253 0.1138
Trypanosoma brucei vacuolar-type Ca2+-ATPase 2 0.0093 0.0359 0.5012
Echinococcus granulosus cathepsin l1 0.0056 0.0191 0.0479
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0098 0.1621
Schistosoma mansoni Smad4 0.0026 0.0057 0.0142
Brugia malayi Sodium/potassium-transporting ATPase alpha chain, putative 0.0056 0.0192 0.0867
Echinococcus granulosus sarco:endoplasmic reticulum calcium ATPase 0.0117 0.0471 0.1182
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0385 0.1694 0.2365
Leishmania major target of rapamycin (TOR) kinase 2, putative 0.0044 0.0137 0.1914
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.3599
Loa Loa (eye worm) phosphatidylinositol 3 0.0015 0.0004 0.0014
Mycobacterium ulcerans metal cation-transporting p-type ATPase F, CtpF 0.0117 0.0471 0.0471
Schistosoma mansoni DNA helicase recq5 0.0019 0.0021 0.0054
Leishmania major target of rapamycin kinase (TOR) kinase 3 0.0035 0.0096 0.1343
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.0067 0.0242 0.2421
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Plasmodium falciparum dipeptidyl aminopeptidase 3 0.0018 0.0019 0.0304
Plasmodium falciparum serine repeat antigen 6 0.0018 0.0019 0.0304
Brugia malayi Animal haem peroxidase family protein 0.0026 0.0055 0.0246
Schistosoma mansoni ankyrin 23/unc44 0.0014 0.0001 0.0001
Echinococcus multilocularis neuropeptide receptor A26 0.046 0.2033 0.5103
Brugia malayi cathepsin F-like cysteine proteinase 0.0018 0.0019 0.0086
Giardia lamblia GTOR 0.0044 0.0137 0.0541
Brugia malayi cathepsin L-like precursor 0.0034 0.0092 0.0413
Entamoeba histolytica cysteine proteinase, putative 0.004 0.0118 0.1956
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Onchocerca volvulus 0.0056 0.0191 0.1825
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.0191 0.0479
Trypanosoma cruzi DNA polymerase kappa, putative 0.0143 0.0586 0.1001
Echinococcus granulosus Niemann Pick C1 protein 0.0097 0.0376 0.0945
Trichomonas vaginalis rod cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Brugia malayi intermediate filament protein 0.0026 0.0057 0.0256
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0347 0.1518 0.2119
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0019 0.0192
Giardia lamblia Cathepsin L-like protease 0.0018 0.0019 0.0075
Echinococcus multilocularis cation transporting atpase worm 0.0026 0.0055 0.0139
Brugia malayi Cathepsin L-like precursor 0.0056 0.0191 0.086
Trypanosoma brucei copper-transporting ATPase-like protein, putative 0.0026 0.0055 0.0771
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0091 0.091
Loa Loa (eye worm) hypothetical protein 0.0117 0.0471 0.1858
Echinococcus granulosus calcium transporting ATPase type 2C member 0.0117 0.0471 0.1182
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0116 0.0468 0.1174
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0068 0.0245 0.0967
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0024 0.0061
Loa Loa (eye worm) pax transcription factor protein 2 0.0243 0.1045 0.4123
Plasmodium vivax serine-repeat antigen 4 (SERA) 0.0018 0.0019 0.0304
Leishmania major hypothetical protein, conserved 0.0069 0.0253 0.3524
Brugia malayi Protein kinase domain containing protein 0.0015 0.0003 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Schistosoma mansoni subfamily C1A non-peptidase homologue (C01 family) 0.0018 0.0019 0.0048
Echinococcus multilocularis chromobox protein 1 0.015 0.0621 0.1558
Brugia malayi cytoplasmic intermediate filament protein 0.0014 0.0001 0.0004
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0214 0.2143
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0034 0.0091 0.0228
Loa Loa (eye worm) cytochrome P450 family protein 0.0016 0.0007 0.0028
Echinococcus granulosus ankyrin repeat and death domain containing protein 0.0014 0.0001 0.0001
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.5947
Schistosoma mansoni lipoxygenase 0.0019 0.0024 0.0061
Trypanosoma brucei FAT domain/Rapamycin binding domain/Phosphatidylinositol 3- and 4-kinase, putative 0.0018 0.002 0.0275
Entamoeba histolytica cysteine proteinase 1, putative 0.004 0.0118 0.1956
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0053 0.0176 0.0176
Leishmania major DNA damage repair protein, putative 0.0036 0.0101 0.1411
Plasmodium falciparum non-SERCA-type Ca2+ -transporting P-ATPase 0.0117 0.0471 0.748
Giardia lamblia Cathepsin L-like protease 0.0018 0.0019 0.0075
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0016 0.0007 0.0007
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.003 0.0074 0.0267
Trypanosoma brucei glucosidase, putative 0.0035 0.0098 0.1366
Mycobacterium tuberculosis Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA 0.1584 0.7163 1
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0214 0.3541
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0019 0.0021 0.0054
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0088 0.0338 0.0849
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0082 0.0308 0.1388
Plasmodium vivax calcium-transporting ATPase, putative 0.0117 0.0471 0.748
Echinococcus multilocularis cpg binding protein 0.003 0.0072 0.0181
Plasmodium vivax serine-repeat antigen 4 (SERA), putative 0.0018 0.0019 0.0304
Onchocerca volvulus 0.0026 0.0055 0.0522
Loa Loa (eye worm) PDE1B protein 0.0069 0.0253 0.0996
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0004 0.0006
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0039 0.0113 0.0508
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.004 0.012 0.1202
Schistosoma mansoni hypothetical protein 0.0051 0.0168 0.0421
Loa Loa (eye worm) animal heme peroxidase 0.0026 0.0055 0.0215
Brugia malayi Cathepsin L-like precursor 0.0056 0.0191 0.086
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0091 0.1504
Schistosoma mansoni SmCB2 peptidase (C01 family) 0.0018 0.0019 0.0048
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0023 0.0041 0.0041
Trypanosoma cruzi DNA polymerase eta, putative 0.0091 0.035 0.0598
Plasmodium falciparum serine repeat antigen 1 0.0018 0.0019 0.0304
Echinococcus granulosus sterol regulatory element binding protein 0.0041 0.0125 0.0314
Schistosoma mansoni tar DNA-binding protein 0.0068 0.0245 0.0615
Echinococcus granulosus plasma membrane calcium transporting ATPase 2 0.0093 0.0359 0.0902
Brugia malayi Probable 3',5'-cyclic phosphodiesterase T04D3.3, putative 0.0069 0.0253 0.1138
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0053 0.0176 0.2462
Toxoplasma gondii Alpha-galactosidase 0.0014 0.0001 0.0004
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0106 0.1067
Trichomonas vaginalis set domain proteins, putative 0.0233 0.0998 1
Schistosoma mansoni hypothetical protein 0.0146 0.0604 0.1517
Trichomonas vaginalis cation-transporting ATPase, putative 0.0093 0.0359 0.3599
Echinococcus granulosus high affinity cAMP specific 3'5' cyclic 0.0069 0.0253 0.0634
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0101 0.1411
Echinococcus multilocularis cAMP and cAMP inhibited cGMP 3',5' cyclic 0.0069 0.0253 0.0634
Echinococcus granulosus Protein patched homolog 1 0.0041 0.0125 0.0314
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0014 0.0001 0.0003
Brugia malayi Cathepsin L-like precursor 0.0034 0.0092 0.0413
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0024 0.0061
Brugia malayi RNA recognition motif domain containing protein 0.0068 0.0245 0.1104
Leishmania major copper-transporting ATPase-like protein, putative 0.0026 0.0055 0.0771
Echinococcus multilocularis L aminoadipate semialdehyde 0.0082 0.0308 0.0773
Echinococcus multilocularis Ankyrin 0.0014 0.0001 0.0003
Trichomonas vaginalis conserved hypothetical protein 0.0089 0.0342 0.3428
Brugia malayi hypothetical protein 0.0051 0.0169 0.076
Onchocerca volvulus 0.0026 0.0055 0.0522
Schistosoma mansoni phosphatidylinositol 3-and 4-kinase 0.0015 0.0004 0.0009
Schistosoma mansoni alpha glucosidase 0.0035 0.0098 0.0246
Leishmania major calcium-translocating P-type ATPase 0.0117 0.0471 0.657
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0055 0.0522
Leishmania major DNA polymerase kappa, putative 0.0123 0.0497 0.6933
Trypanosoma brucei cAMP-specific phosphodiesterase 0.0069 0.0253 0.3524
Schistosoma mansoni high-affinity cgmp-specific 35-cyclic phosphodiesterase 0.0069 0.0253 0.0634
Trypanosoma cruzi copper-transporting ATPase-like protein, putative 0.0026 0.0055 0.0094
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0164 0.1644
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0176 0.0176
Brugia malayi cathepsin L-like cysteine proteinase 0.0018 0.0019 0.0086
Toxoplasma gondii NADPH-glutathione reductase 0.0053 0.0176 0.0636
Schistosoma mansoni blooms syndrome DNA helicase 0.0036 0.0099 0.0249
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0032 0.0084 0.0211
Plasmodium vivax serine-repeat antigen (SERA) 0.0018 0.0019 0.0304
Trichomonas vaginalis Clan CA, family C1, cathepsin L or H-like cysteine peptidase 0.0018 0.0019 0.0192
Plasmodium vivax 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.4012
Trichomonas vaginalis r2r3-MYB transcription factor, putative 0.0061 0.0214 0.2143
Trypanosoma cruzi DNA polymerase kappa, putative 0.0143 0.0586 0.1001
Brugia malayi hypothetical protein 0.0122 0.0493 0.2223
Brugia malayi follicle stimulating hormone receptor 0.0234 0.1004 0.4524
Leishmania major calcium motive p-type ATPase, putative 0.0066 0.0238 0.332
Schistosoma mansoni smad1 5 8 and 0.0026 0.0057 0.0142
Echinococcus granulosus mitogen activated protein kinase 3 0.005 0.0164 0.0412
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0448
Trypanosoma cruzi phosphatidylinositol 3-related kinase, putative 0.0015 0.0004 0.0006
Echinococcus granulosus thioredoxin glutathione reductase 0.0152 0.063 0.1581
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0067 0.0242 0.0607
Entamoeba histolytica cation-transporting P-typeATPase, putative 0.0026 0.0055 0.0914
Leishmania major cathepsin L-like protease 0.0056 0.0191 0.2661
Mycobacterium ulcerans metal cation transporter p-type ATPase, CtpV 0.0026 0.0055 0.0055
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0023 0.0041 0.0648
Trypanosoma brucei DNA polymerase kappa, putative 0.0062 0.022 0.3069
Loa Loa (eye worm) calcium ATPase 0.002 0.0026 0.0102
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0253 0.253
Echinococcus multilocularis Chromo domain 0.0034 0.0091 0.0228
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.005 0.0164 0.2289
Leishmania major cysteine peptidase C (CPC),CPC cysteine peptidase, Clan CA, family C1, Cathepsin B-like 0.0018 0.0019 0.0267
Loa Loa (eye worm) MH1 domain-containing protein 0.0026 0.0057 0.0223
Schistosoma mansoni rab6-interacting 0.0019 0.0024 0.0061
Trichomonas vaginalis Clan CA, family C1, cathepsin B-like cysteine peptidase 0.0018 0.0019 0.0192
Schistosoma mansoni netrin receptor unc5 0.0014 0.0001 0.0001
Trypanosoma cruzi cytochrome P450, putative 0.0016 0.0007 0.0012
Loa Loa (eye worm) phosphatidylinositol 3 0.0044 0.0137 0.0541
Brugia malayi Cytochrome P450 family protein 0.0016 0.0007 0.0032
Plasmodium vivax glutathione reductase, putative 0.0152 0.063 1
Trypanosoma cruzi DNA damage repair protein, putative 0.0036 0.0101 0.0173
Plasmodium vivax hypothetical protein, conserved 0.0034 0.0091 0.1443
Schistosoma mansoni loxhd1 0.0019 0.0024 0.0061
Onchocerca volvulus 0.0056 0.0191 0.1825
Plasmodium vivax serine-repeat antigen (SERA), putative 0.0018 0.0019 0.0304
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0183 0.046
Loa Loa (eye worm) hypothetical protein 0.0019 0.0021 0.0084
Giardia lamblia Encystation-specific protease 0.0018 0.0019 0.0075
Schistosoma mansoni terminal deoxycytidyl transferase 0.0116 0.0468 0.1174
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0098 0.0981
Entamoeba histolytica calcium-transporting P-type ATPase, putative 0.0083 0.0313 0.5186
Trichomonas vaginalis cAMP-specific phosphodiesterase, putative 0.0069 0.0253 0.253
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0069 0.0253 0.1138
Brugia malayi Calcitonin receptor-like protein seb-1 0.0102 0.0403 0.1818
Echinococcus multilocularis phosphoserine phosphatase 0.0017 0.0012 0.0029
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.005 0.0164 0.028
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0023 0.004 0.0102
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0019 0.0021 0.0054
Trichomonas vaginalis cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0665 0.1669
Chlamydia trachomatis metal transport ATPase 0.0026 0.0055 0.0055
Leishmania major calcium-transporting ATPase, putative 0.0066 0.0238 0.332
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0019 0.0021 0.0096
Trichomonas vaginalis PIKK family atypical protein kinase 0.0035 0.0096 0.0962
Loa Loa (eye worm) sodium/potassium-transporting ATPase subunit alpha 0.0056 0.0192 0.0759
Onchocerca volvulus Peroxidasin homolog 0.0026 0.0055 0.0522
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0101 0.0173
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Schistosoma mansoni hypothetical protein 0.0034 0.0091 0.0228
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0169 0.0288
Mycobacterium tuberculosis Conserved hypothetical protein 0.0116 0.0468 0.0653
Loa Loa (eye worm) ctsf protein 0.0056 0.0191 0.0752
Schistosoma mansoni calcium-transporting atpase sarcoplasmic/endoplasmic reticulum type (calcium pump) 0.0101 0.0396 0.0993
Trypanosoma cruzi cruzipain precursor, putative 0.0148 0.0612 0.1044
Trichomonas vaginalis conserved hypothetical protein 0.0034 0.0091 0.091
Echinococcus multilocularis sterol regulatory element binding protein 0.0041 0.0125 0.0314
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.0091 0.0228
Trichomonas vaginalis cGMP-dependent 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0066 0.0238 0.0406
Onchocerca volvulus Cathepsin F homolog 0.0056 0.0191 0.1825
Loa Loa (eye worm) hypothetical protein 0.0067 0.0242 0.0953
Trichomonas vaginalis DNA helicase recq, putative 0.0024 0.0046 0.0465
Entamoeba histolytica chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0091 0.1504
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0024 0.0046 0.0079
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Brugia malayi CHD4 protein 0.0036 0.0098 0.0443
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.004 0.0118 0.1648
Echinococcus granulosus X box binding protein 1 0.0282 0.1225 0.3075
Trypanosoma brucei phosphatidylinositol 3-related kinase, putative 0.0015 0.0004 0.0051
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0073 0.0182
Trichomonas vaginalis plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.3599
Trichomonas vaginalis conserved hypothetical protein 0.0055 0.0188 0.1879
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0056 0.0191 0.1911
Loa Loa (eye worm) TAR-binding protein 0.0068 0.0245 0.0967
Trypanosoma brucei DNA polymerase kappa, putative 0.0143 0.0586 0.8181
Brugia malayi Cytochrome P450 family protein 0.0026 0.0053 0.024
Echinococcus granulosus bloom syndrome protein 0.0045 0.0143 0.0358
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.005 0.0164 0.028
Brugia malayi Papain family cysteine protease containing protein 0.004 0.0118 0.0532
Giardia lamblia DINP protein human, muc B family 0.0123 0.0497 0.196
Schistosoma mansoni cathepsin F (C01 family) 0.0034 0.0092 0.023
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma cruzi proton motive ATPase 1, putative 0.0017 0.0012 0.002
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0665 0.1669
Leishmania major DNA polymerase kappa, putative 0.0036 0.0101 0.1411
Echinococcus granulosus Ca2 transporting ATPase plasma membrane 0.0076 0.0284 0.0713
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0056 0.0564
Schistosoma mansoni hypothetical protein 0.0032 0.0084 0.0211
Trichomonas vaginalis PIKK family atypical protein kinase 0.0033 0.0086 0.0858
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Schistosoma mansoni chromobox protein-related (chromobox 1) (heterochromatin 1) 0.0034 0.0091 0.0228
Mycobacterium ulcerans cation-transporter p-type ATPase B CtpB 0.0026 0.0055 0.0055
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Echinococcus granulosus cAMP and cAMP inhibited cGMP 3'5' cyclic 0.0069 0.0253 0.0634
Schistosoma mansoni smad1 5 8 and 0.0026 0.0057 0.0142
Loa Loa (eye worm) hypothetical protein 0.0061 0.0215 0.0846
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0024 0.0096
Schistosoma mansoni hypothetical protein 0.0014 0.0001 0.0001
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0053 0.0176 0.2462
Trichomonas vaginalis cation-transporting ATPase, putative 0.0117 0.0471 0.4717
Echinococcus granulosus phospholipid transporting ATPase IIB 0.0026 0.0055 0.0139
Trypanosoma cruzi P-type H+-ATPase, putative 0.0053 0.0176 0.0301
Leishmania major cysteine peptidase A (CPA) 0.0056 0.0191 0.2661
Onchocerca volvulus Peroxidase homolog 0.0026 0.0055 0.0522
Loa Loa (eye worm) calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type 0.0074 0.0275 0.1083
Trypanosoma cruzi cysteine peptidase, putative 0.0148 0.0612 0.1044
Brugia malayi latrophilin 2 splice variant baaae 0.007 0.0256 0.1152
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Plasmodium vivax vivapain-2 0.0056 0.0191 0.303
Trypanosoma brucei cysteine peptidase C (CPC) 0.0018 0.0019 0.0267
Echinococcus granulosus death domain containing protein 0.0014 0.0001 0.0001
Brugia malayi hypothetical protein 0.0019 0.0024 0.011
Plasmodium vivax dipeptidyl aminopeptidase 1, putative 0.0018 0.0019 0.0304
Trichomonas vaginalis calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.253
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0034 0.0091 0.091
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0053 0.0176 0.0176
Brugia malayi hypothetical protein 0.0033 0.0086 0.0389
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0098 0.0353
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0214 0.3541
Trichomonas vaginalis cAMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Echinococcus multilocularis thioredoxin glutathione reductase 0.0152 0.063 0.1581
Brugia malayi Cathepsin L-like cysteine proteinase 0.0034 0.0092 0.0413
Giardia lamblia Cathepsin L precursor 0.0018 0.0019 0.0075
Echinococcus granulosus tar DNA binding protein 0.0068 0.0245 0.0615
Onchocerca volvulus Huntingtin homolog 0.012 0.0484 0.4632
Schistosoma mansoni hypothetical protein 0.0282 0.1225 0.3075
Trypanosoma brucei DNA polymerase IV, putative 0.0143 0.0586 0.8181
Loa Loa (eye worm) cathepsin B 0.0018 0.0019 0.0075
Loa Loa (eye worm) fibroinase 0.0056 0.0191 0.0752
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0055 0.0552
Echinococcus granulosus calcium transporting atpase 0.0101 0.0396 0.0993
Brugia malayi Pre-SET motif family protein 0.003 0.0073 0.0327
Trypanosoma cruzi PAB1-binding protein , putative 0.0051 0.0169 0.0288
Loa Loa (eye worm) CHromoDomain protein family member 0.0036 0.0098 0.0387
Onchocerca volvulus 0.0028 0.0065 0.0619
Entamoeba histolytica cysteine protease, putative 0.0018 0.0019 0.0317
Schistosoma mansoni ataxia telangiectasia mutated (atm)-related 0.0044 0.0137 0.0344
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Trichomonas vaginalis conserved hypothetical protein 0.0069 0.0253 0.253
Onchocerca volvulus 0.0056 0.0191 0.1825
Plasmodium vivax serine-repeat antigen 5 (SERA) 0.0018 0.0019 0.0304
Entamoeba histolytica papain family cysteine protease domain containing protein 0.0018 0.0019 0.0317
Entamoeba histolytica Plasma membrane calcium-transporting ATPase, putative 0.0093 0.0359 0.5947
Echinococcus granulosus phospholipid transporting ATPase VA 0.0017 0.0012 0.0029
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Trichomonas vaginalis PIKK family atypical protein kinase 0.0024 0.0045 0.0447
Trypanosoma cruzi cyclic nucleotide phosphodiesterase 0.0069 0.0253 0.0431
Plasmodium falciparum glutathione reductase 0.0152 0.063 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Leishmania major cathepsin L-like protease 0.0056 0.0191 0.2661
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0053 0.0176 0.0636
Trypanosoma brucei 3', 5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.3524
Entamoeba histolytica cysteine protease, putative 0.004 0.0118 0.1956
Loa Loa (eye worm) sodium potassium adenosine triphosphatase 0.0036 0.0101 0.0398
Trypanosoma brucei cation-transporting ATPase, putative 0.0026 0.0055 0.0771
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0053 0.0176 0.2462
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0056 0.0191 0.0479
Trichomonas vaginalis CMGC family protein kinase 0.005 0.0164 0.1644
Trichomonas vaginalis chromobox protein, putative 0.0034 0.0091 0.091
Schistosoma mansoni ATPase 0.0117 0.0471 0.1182
Leishmania major hypothetical protein, conserved 0.0069 0.0253 0.3524
Brugia malayi MH1 domain containing protein 0.0015 0.0003 0.0012
Trichomonas vaginalis PIKK family atypical protein kinase 0.003 0.0071 0.0712
Echinococcus multilocularis Ca2+ transporting ATPase plasma membrane 0.0076 0.0284 0.0713
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0069 0.0253 0.0911
Giardia lamblia Cathepsin B precursor 0.0018 0.0019 0.0075
Trypanosoma brucei vacuolar-type Ca2+-ATPase, putative 0.0093 0.0359 0.5012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Mycobacterium tuberculosis Cation transporter P-type ATPase a CtpA 0.0026 0.0055 0.0077
Trypanosoma cruzi cation-transporting ATPase, putative 0.0026 0.0055 0.0094
Brugia malayi hypothetical protein 0.0119 0.0481 0.2166
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0665 0.2996
Schistosoma mansoni microtubule-associated protein tau 0.0677 0.3022 0.7588
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0019 0.0192
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0024 0.0388
Entamoeba histolytica myb-like DNA-binding domain containing protein 0.0061 0.0214 0.3541
Brugia malayi Cathepsin L-like precursor 0.0056 0.0191 0.086
Loa Loa (eye worm) intermediate filament protein 0.0026 0.0057 0.0224
Mycobacterium ulcerans hypothetical protein 0.0036 0.0101 0.0101
Mycobacterium tuberculosis Probable dehydrogenase 0.0347 0.1518 0.2119
Echinococcus granulosus Na:K ATPase alpha subunit 0.0066 0.0238 0.0598
Brugia malayi Uncoordinated protein 44 0.0014 0.0001 0.0002
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0053 0.0176 0.2462
Mycobacterium leprae probable 3-phosphoshikimate 1-carboxyvinyl transferase AroA (5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE SYNTHASE) (EPSP SYNTHASE) (EPSPS 0.0622 0.2773 0.3872
Onchocerca volvulus 0.0122 0.0493 0.4715
Echinococcus granulosus cathepsin L 0.0018 0.0019 0.0048
Onchocerca volvulus 0.0019 0.0024 0.0233
Mycobacterium tuberculosis Probable cation transporter P-type ATPase D CtpD 0.0026 0.0055 0.0077
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0019 0.0192
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0148 0.0612 0.8532
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0056 0.0191 0.1911
Trypanosoma cruzi hypothetical protein, conserved 0.0069 0.0253 0.0431
Giardia lamblia Hypothetical protein 0.0018 0.0019 0.0075
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.01 0.0394 0.099
Loa Loa (eye worm) hypothetical protein 0.0014 0.0001 0.0004
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0053 0.0176 0.2462
Entamoeba histolytica cysteine proteinase 2 0.004 0.0118 0.1956
Schistosoma mansoni cathepsin B-like peptidase (C01 family) 0.0018 0.0019 0.0048
Brugia malayi fibroinase precursor 0.0018 0.0019 0.0086
Entamoeba histolytica cysteine protease, putative 0.0018 0.0019 0.0317
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0385 0.1694 0.2365
Loa Loa (eye worm) hypothetical protein 0.0026 0.0055 0.0215
Echinococcus multilocularis Niemann Pick C1 protein 0.0138 0.0565 0.142
Trichomonas vaginalis PIKK family atypical protein kinase 0.0026 0.0055 0.0552
Entamoeba histolytica cysteine proteinase, putative 0.0056 0.0191 0.3158
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0019 0.0192
Trypanosoma cruzi calcium motive p-type ATPase, putative 0.0066 0.0238 0.0406
Plasmodium falciparum 3',5'-cyclic nucleotide phosphodiesterase, putative 0.0069 0.0253 0.4012
Trichomonas vaginalis cGMP-specific 3,5-cyclic phosphodiesterase, putative 0.0069 0.0253 0.253
Brugia malayi Intermediate filament tail domain containing protein 0.0026 0.0057 0.0256
Loa Loa (eye worm) hypothetical protein 0.0048 0.0157 0.0621
Echinococcus multilocularis neuropeptide s receptor 0.046 0.2033 0.5103
Brugia malayi polk-prov protein 0.0062 0.022 0.0992
Leishmania major hypothetical protein, conserved 0.0051 0.0169 0.2351
Schistosoma mansoni cation-transporting atpase worm 0.0026 0.0055 0.0139
Echinococcus granulosus lamin dm0 0.0026 0.0057 0.0143
Trichomonas vaginalis PIKK family atypical protein kinase 0.0044 0.0137 0.1374

Activities

Activity type Activity value Assay description Source Reference
CC50 (functional) > 100 uM Cytotoxicity of the compound was evaluated against uninfected MT-4 cells ChEMBL. 9873448
CC50 (functional) > 100 uM Cytotoxicity of the compound was evaluated against uninfected MT-4 cells ChEMBL. 9873448
IC50 (functional) = 0.1 uM Inhibitory activity against syncytia formation in HIV-infected MT-4 cells was evaluated ChEMBL. 9873448
IC50 (functional) = 0.1 uM Inhibitory activity against syncytia formation in HIV-infected MT-4 cells was evaluated ChEMBL. 9873448
Inhibition (binding) = 19 % In vitro inhibitory activity of the compound against HIV-1 protease at a concentration of 10 microM ChEMBL. No reference
Inhibition (binding) = 19 % In vitro inhibitory activity of the compound against HIV-1 protease at a concentration of 10 microM ChEMBL. No reference
logP (ADMET) = 5.12 Partition coefficient (logP) ChEMBL. 9873448

Phenotypes

Whole-cell/tissue/organism interactions

Species name Source Reference Is orphan
Homo sapiens ChEMBL23 9873448

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

1 literature reference was collected for this gene.

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