Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | chromobox protein homolog 3 | 0.0041 | 0.1095 | 0.1095 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.0032 | 0.0667 | 0.0982 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.5238 | 0.7706 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.0032 | 0.0667 | 0.0982 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0027 | 0.004 |
Trichomonas vaginalis | chromobox protein, putative | 0.0073 | 0.254 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.1235 | 0.3419 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0027 | 0.004 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1956 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.0032 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | steroid hormone receptor | 0.0032 | 0.0667 | 0.0667 |
Echinococcus granulosus | chromobox protein 1 | 0.0073 | 0.254 | 0.3736 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0667 | 0.0667 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.049 | 0.5 |
Brugia malayi | nuclear receptor NHR-88 | 0.0032 | 0.0667 | 0.0667 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.049 | 0.5 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.0032 | 0.0667 | 0.0667 |
Echinococcus multilocularis | chromobox protein 1 | 0.0073 | 0.254 | 0.3736 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0027 | 0.004 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.0032 | 0.0667 | 0.0982 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1956 | 0.5 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0239 | 1 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0667 | 0.0667 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.0032 | 0.0667 | 0.0982 |
Onchocerca volvulus | 0.0032 | 0.0697 | 0.0524 | |
Echinococcus granulosus | tar DNA binding protein | 0.0133 | 0.5238 | 0.7706 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.0032 | 0.0667 | 0.0982 |
Echinococcus multilocularis | tar DNA binding protein | 0.0133 | 0.5238 | 0.7706 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0667 | 0.0667 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0032 | 0.0667 | 0.0667 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.0032 | 0.0667 | 0.0667 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.0032 | 0.0667 | 0.0982 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0032 | 0.0667 | 0.0667 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0032 | 0.0667 | 0.0667 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0032 | 0.0667 | 0.0667 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.0032 | 0.0667 | 0.0667 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0027 | 0.004 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.0032 | 0.0667 | 0.0667 |
Echinococcus granulosus | GPCR family 2 | 0.0017 | 0.0027 | 0.004 |
Echinococcus granulosus | aldehyde dehydrogenase mitochondrial | 0.006 | 0.1956 | 0.2878 |
Schistosoma mansoni | hypothetical protein | 0.0037 | 0.0926 | 0.1362 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.0032 | 0.0667 | 0.0982 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0032 | 0.0667 | 0.0667 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.0032 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0239 | 1 | 1 |
Brugia malayi | ecdysteroid receptor | 0.0032 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.0032 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.0032 | 0.0667 | 0.0667 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0032 | 0.0667 | 0.0982 |
Mycobacterium ulcerans | aldehyde dehydrogenase | 0.006 | 0.1956 | 0.5 |
Echinococcus multilocularis | aldehyde dehydrogenase, mitochondrial | 0.006 | 0.1956 | 0.2878 |
Schistosoma mansoni | nuclear hormone receptor | 0.0032 | 0.0667 | 0.0982 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.3356 | 0.4936 |
Plasmodium falciparum | ataxin-2 like protein, putative | 0.0028 | 0.049 | 0.5 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.0032 | 0.0667 | 0.0982 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.0032 | 0.0667 | 0.0667 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.1095 | 0.2714 |
Loa Loa (eye worm) | hypothetical protein | 0.0028 | 0.049 | 0.049 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.0032 | 0.0667 | 0.0982 |
Trypanosoma cruzi | PAB1-binding protein , putative | 0.0028 | 0.049 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0667 | 0.0667 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.0032 | 0.0667 | 0.0982 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.5238 | 0.7706 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0032 | 0.0667 | 0.0982 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.0032 | 0.0667 | 0.0667 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.3356 | 0.4936 |
Schistosoma mansoni | chromobox protein | 0.0073 | 0.254 | 0.3736 |
Loa Loa (eye worm) | hypothetical protein | 0.0055 | 0.17 | 0.17 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0041 | 0.1095 | 0.7536 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.3356 | 0.4936 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0027 | 0.004 |
Schistosoma mansoni | thyroid hormone receptor | 0.0032 | 0.0667 | 0.0982 |
Loa Loa (eye worm) | heterochromatin protein 1 | 0.0073 | 0.254 | 0.254 |
Echinococcus multilocularis | GPCR, family 2 | 0.0017 | 0.0027 | 0.004 |
Brugia malayi | Heterochromatin protein 1 | 0.0073 | 0.254 | 0.254 |
Brugia malayi | hypothetical protein | 0.0018 | 0.0051 | 0.0051 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0055 | 0.17 | 0.17 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0133 | 0.5238 | 0.5238 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.6798 | 1 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0133 | 0.5238 | 0.5238 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.6798 | 1 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.0032 | 0.0667 | 0.0982 |
Brugia malayi | hypothetical protein | 0.0028 | 0.049 | 0.049 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.0032 | 0.0667 | 0.0667 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0091 | 0.3356 | 0.3356 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.0032 | 0.0667 | 0.0667 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.0032 | 0.0667 | 0.0982 |
Brugia malayi | steroid hormone receptor | 0.0032 | 0.0667 | 0.0667 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0037 | 0.0926 | 0.0926 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0017 | 0.0027 | 0.0027 |
Brugia malayi | TAR-binding protein | 0.0133 | 0.5238 | 0.5238 |
Echinococcus multilocularis | FTZ F1 alpha | 0.0032 | 0.0667 | 0.0982 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0667 | 0.0667 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.0032 | 0.0667 | 0.0982 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.0032 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0667 | 0.0667 |
Echinococcus granulosus | FTZ F1 alpha | 0.0032 | 0.0667 | 0.0982 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.0032 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0091 | 0.3356 | 0.3356 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.1956 | 0.2878 |
Loa Loa (eye worm) | hypothetical protein | 0.0037 | 0.0926 | 0.0926 |
Brugia malayi | nuclear hormone receptor | 0.0032 | 0.0667 | 0.0667 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.0028 | 0.049 | 0.5 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0017 | 0.0027 | 0.004 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.3356 | 0.4936 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0017 | 0.0027 | 0.0027 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.0032 | 0.0667 | 0.0667 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0697 | 0.0697 |
Trypanosoma brucei | PAB1-binding protein , putative | 0.0028 | 0.049 | 0.5 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0091 | 0.3356 | 0.4936 |
Echinococcus multilocularis | chromobox protein 1 | 0.0073 | 0.254 | 0.3736 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.0032 | 0.0667 | 0.0982 |
Onchocerca volvulus | Heterochromatin protein 1 homolog | 0.0044 | 0.1235 | 1 |
Trichomonas vaginalis | chromobox protein, putative | 0.0044 | 0.1235 | 0.3419 |
Trichomonas vaginalis | chromobox protein, putative | 0.0073 | 0.254 | 1 |
Mycobacterium tuberculosis | Probable aldehyde dehydrogenase | 0.006 | 0.1956 | 0.5 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.0032 | 0.0667 | 0.0982 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0055 | 0.17 | 0.17 |
Echinococcus granulosus | geminin | 0.0168 | 0.6798 | 1 |
Schistosoma mansoni | chromobox protein | 0.0073 | 0.254 | 0.3736 |
Loa Loa (eye worm) | hypothetical protein | 0.0041 | 0.1095 | 0.1095 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.0032 | 0.0667 | 0.0667 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0017 | 0.0027 | 0.004 |
Echinococcus multilocularis | geminin | 0.0168 | 0.6798 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0667 | 0.0667 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0091 | 0.3356 | 0.4936 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.5238 | 0.7706 |
Loa Loa (eye worm) | RNA binding protein | 0.0133 | 0.5238 | 0.5238 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.0032 | 0.0667 | 0.0982 |
Schistosoma mansoni | coup transcription factor | 0.0032 | 0.0667 | 0.0982 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.5238 | 0.7706 |
Loa Loa (eye worm) | TAR-binding protein | 0.0133 | 0.5238 | 0.5238 |
Schistosoma mansoni | hypothetical protein | 0.0017 | 0.0027 | 0.004 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.0032 | 0.0667 | 0.0982 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.0032 | 0.0667 | 0.0982 |
Leishmania major | aldehyde dehydrogenase, mitochondrial precursor | 0.006 | 0.1956 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0091 | 0.3356 | 0.4936 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0032 | 0.0667 | 0.0982 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0017 | 0.0027 | 0.0027 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.0032 | 0.0667 | 0.0667 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0032 | 0.0667 | 0.0982 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.0032 | 0.0667 | 0.0982 |
Toxoplasma gondii | aldehyde dehydrogenase | 0.006 | 0.1956 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0041 | 0.1095 | 0.2714 |
Loa Loa (eye worm) | hypothetical protein | 0.0032 | 0.0667 | 0.0667 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.0032 | 0.0667 | 0.0982 |
Brugia malayi | RNA binding protein | 0.0133 | 0.5238 | 0.5238 |
Echinococcus granulosus | chromobox protein 1 | 0.0073 | 0.254 | 0.3736 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0055 | 0.17 | 0.17 |
Schistosoma mansoni | tar DNA-binding protein | 0.0133 | 0.5238 | 0.7706 |
Loa Loa (eye worm) | hypothetical protein | 0.0017 | 0.0027 | 0.0027 |
Schistosoma mansoni | aldehyde dehydrogenase | 0.006 | 0.1956 | 0.2878 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0032 | 0.0667 | 0.0982 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.0032 | 0.0667 | 0.0667 |
Schistosoma mansoni | thyroid hormone receptor | 0.0032 | 0.0667 | 0.0982 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.