Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1375 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0026 | 0.382 | 0.3787 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0634 | 0.1257 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0007 | 0.0634 | 0.1257 |
Entamoeba histolytica | T-complex protein 1 beta subunit, putative | 0.0026 | 0.382 | 1 |
Plasmodium vivax | T-complex protein 1 subunit beta, putative | 0.0026 | 0.382 | 1 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0026 | 0.382 | 0.8679 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.2667 | 0.5651 |
Plasmodium falciparum | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.2667 | 0.6939 |
Mycobacterium tuberculosis | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) | 0.0019 | 0.2667 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1375 |
Trichomonas vaginalis | ocrl type II inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0139 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0055 | 0.8867 | 1 |
Leishmania major | apurinic/apyrimidinic endonuclease-redox protein | 0.0019 | 0.2667 | 0.6939 |
Trypanosoma cruzi | T-complex protein 1, beta subunit, putative | 0.0026 | 0.382 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1375 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0053 | 0.0139 |
Leishmania major | T-complex protein 1, beta subunit, putative | 0.0026 | 0.382 | 1 |
Plasmodium vivax | AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative | 0.0019 | 0.2667 | 0.6939 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1375 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1375 |
Brugia malayi | CXXC zinc finger family protein | 0.0029 | 0.4393 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0029 | 0.4393 | 0.4363 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0029 | 0.4393 | 1 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.4678 | 0.465 |
Onchocerca volvulus | 0.0029 | 0.4393 | 1 | |
Trichomonas vaginalis | type II inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0139 |
Toxoplasma gondii | exonuclease III APE | 0.0019 | 0.2667 | 0.2966 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0026 | 0.382 | 0.3787 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease | 0.0019 | 0.2667 | 0.6939 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1375 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0007 | 0.0634 | 0.1257 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0525 | 0.1375 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0053 | 0.0139 |
Trypanosoma cruzi | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.2667 | 0.6939 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1375 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1375 |
Toxoplasma gondii | t-complex protein beta subunit | 0.0026 | 0.382 | 0.4274 |
Trichomonas vaginalis | sphingomyelinase C 2 precursor, putative | 0.0004 | 0.0053 | 0.0139 |
Trichomonas vaginalis | helicase, putative | 0.0007 | 0.0525 | 0.1375 |
Treponema pallidum | exodeoxyribonuclease (exoA) | 0.0019 | 0.2667 | 1 |
Trichomonas vaginalis | type IV inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0139 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.2667 | 0.6982 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1375 |
Echinococcus multilocularis | chaperonin containing TCP1, subunit 2 (beta) | 0.0026 | 0.382 | 0.8144 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0009 | 0.092 | 0.1996 |
Trichomonas vaginalis | chromodomain-helicase-DNA-binding protein, putative | 0.0007 | 0.0525 | 0.1375 |
Trypanosoma brucei | T-complex protein 1, beta subunit, putative | 0.0026 | 0.382 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.2667 | 0.2628 |
Giardia lamblia | TCP-1 chaperonin subunit beta | 0.0026 | 0.382 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0007 | 0.0634 | 0.0584 |
Giardia lamblia | Endonuclease/Exonuclease/phosphatase | 0.0019 | 0.2667 | 0.6939 |
Loa Loa (eye worm) | T-complex protein 1 | 0.0026 | 0.382 | 0.8679 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.2667 | 0.6023 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1375 |
Loa Loa (eye worm) | histone methyltransferase | 0.0009 | 0.0939 | 0.2042 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.2667 | 0.6023 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.1916 |
Brugia malayi | T-complex protein 1, beta subunit | 0.0026 | 0.382 | 0.8679 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0939 | 0.1916 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.2667 | 0.5651 |
Echinococcus granulosus | cpg binding protein | 0.0031 | 0.4678 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1375 |
Trichomonas vaginalis | Phospholipase C precursor, putative | 0.0004 | 0.0053 | 0.0139 |
Schistosoma mansoni | cpg binding protein | 0.0031 | 0.4678 | 0.465 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1375 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.2667 | 0.2628 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0007 | 0.0634 | 0.1257 |
Mycobacterium ulcerans | exodeoxyribonuclease III protein XthA | 0.0019 | 0.2667 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1375 |
Trichomonas vaginalis | chaperonin, putative | 0.0026 | 0.382 | 1 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0004 | 0.0109 | 0.0056 |
Plasmodium falciparum | T-complex protein 1 subunit beta | 0.0026 | 0.382 | 1 |
Trichomonas vaginalis | chaperonin-60kD, ch60, putative | 0.0026 | 0.382 | 1 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0007 | 0.0525 | 0.1375 |
Trichomonas vaginalis | carbon catabolite repressor protein, putative | 0.0004 | 0.0053 | 0.0139 |
Schistosoma mansoni | chaperonin containing t-complex protein 1 beta subunit tcpb | 0.0026 | 0.382 | 0.3787 |
Trichomonas vaginalis | skeletal muscle/kidney enriched inositol 5-phosphatase, putative | 0.0004 | 0.0053 | 0.0139 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.2667 | 0.6982 |
Wolbachia endosymbiont of Brugia malayi | exonuclease III | 0.0019 | 0.2667 | 0.5 |
Trichomonas vaginalis | chromodomain helicase DNA binding protein, putative | 0.0007 | 0.0525 | 0.1375 |
Trypanosoma brucei | apurinic/apyrimidinic endonuclease, putative | 0.0019 | 0.2667 | 0.6939 |
Echinococcus granulosus | chaperonin containing TCP1 subunit 2 beta | 0.0026 | 0.382 | 0.8144 |
Entamoeba histolytica | exodeoxyribonuclease III, putative | 0.0019 | 0.2667 | 0.6939 |
Echinococcus multilocularis | cpg binding protein | 0.0031 | 0.4678 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.