Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma brucei | P-type H+-ATPase, putative | 0.0008 | 0 | 0.5 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-A | 0.0043 | 0.2504 | 1 |
Trypanosoma cruzi | P-type H+-ATPase, putative | 0.0008 | 0 | 0.5 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 1 | 0.0008 | 0 | 0.5 |
Mycobacterium ulcerans | cation-transporter p-type ATPase B CtpB | 0.0008 | 0 | 0.5 |
Onchocerca volvulus | 0.0008 | 0 | 0.5 | |
Brugia malayi | RNA recognition motif domain containing protein | 0.0063 | 0.4022 | 0.4022 |
Mycobacterium ulcerans | metal cation-transporting p-type ATPase F, CtpF | 0.0008 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.4022 | 0.4022 |
Mycobacterium leprae | PROBABLE CATION-TRANSPORTER ATPASE I CTPI | 0.0008 | 0 | 0.5 |
Mycobacterium tuberculosis | Probable cation transporter P-type ATPase D CtpD | 0.0008 | 0 | 0.5 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0043 | 0.2504 | 0.258 |
Mycobacterium ulcerans | cation transporter p-type ATPase a CtpA | 0.0008 | 0 | 0.5 |
Giardia lamblia | Histone acetyltransferase GCN5 | 0.0039 | 0.2243 | 1 |
Mycobacterium tuberculosis | Probable metal cation transporter ATPase P-type CtpE | 0.0008 | 0 | 0.5 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0063 | 0.4022 | 0.4022 |
Treponema pallidum | cation-transporting ATPase, P-type | 0.0008 | 0 | 0.5 |
Trypanosoma brucei | copper-transporting ATPase-like protein, putative | 0.0008 | 0 | 0.5 |
Mycobacterium tuberculosis | Possible metal cation transporting P-type ATPase CtpH | 0.0008 | 0 | 0.5 |
Leishmania major | vacuolar-type Ca2 -ATPase, putative | 0.0008 | 0 | 0.5 |
Trypanosoma cruzi | copper-transporting ATPase, putative | 0.0008 | 0 | 0.5 |
Trypanosoma cruzi | copper-transporting ATPase-like protein, putative | 0.0008 | 0 | 0.5 |
Trichomonas vaginalis | cat eye syndrome critical region protein 2, cscr2, putative | 0.0043 | 0.2504 | 1 |
Loa Loa (eye worm) | TAR-binding protein | 0.0063 | 0.4022 | 0.4022 |
Plasmodium falciparum | histone acetyltransferase GCN5 | 0.0039 | 0.2243 | 1 |
Echinococcus multilocularis | gcn5proteinral control of amino acid synthesis | 0.0145 | 1 | 1 |
Mycobacterium ulcerans | cation-transporter ATPase I CtpI | 0.0008 | 0 | 0.5 |
Leishmania major | vacuolar-type Ca2 -ATPase, putative | 0.0008 | 0 | 0.5 |
Trypanosoma cruzi | Calcium ATPase SERCA-like | 0.0008 | 0 | 0.5 |
Treponema pallidum | hypothetical protein | 0.0008 | 0 | 0.5 |
Trypanosoma cruzi | cation-transporting ATPase, putative | 0.0008 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.4022 | 0.4022 |
Brugia malayi | RNA binding protein | 0.0063 | 0.4022 | 0.4022 |
Leishmania major | calcium-translocating P-type ATPase | 0.0008 | 0 | 0.5 |
Plasmodium vivax | histone acetyltransferase GCN5, putative | 0.0043 | 0.2504 | 1 |
Brugia malayi | TAR-binding protein | 0.0063 | 0.4022 | 0.4022 |
Mycobacterium ulcerans | metal cation transporter ATPase p-type CtpE | 0.0008 | 0 | 0.5 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase 2 | 0.0008 | 0 | 0.5 |
Schistosoma mansoni | gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 | 0.0145 | 1 | 1 |
Trypanosoma brucei | P-type H+-ATPase, putative | 0.0008 | 0 | 0.5 |
Leishmania major | P-type H -ATPase, putative | 0.0008 | 0 | 0.5 |
Mycobacterium leprae | Probable metal cation-transporting P-type ATPase C CtpC | 0.0008 | 0 | 0.5 |
Trypanosoma cruzi | copper-transporting ATPase-like protein, putative | 0.0008 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.5837 | 0.5837 |
Trypanosoma brucei | cation-transporting ATPase, putative | 0.0008 | 0 | 0.5 |
Mycobacterium ulcerans | cation transporter p-type ATPase D CtpD | 0.0008 | 0 | 0.5 |
Trypanosoma cruzi | P-type H+-ATPase, putative | 0.0008 | 0 | 0.5 |
Entamoeba histolytica | acetyltransferase, GNAT family | 0.0039 | 0.2243 | 1 |
Trichomonas vaginalis | bromodomain-containing protein, putative | 0.0043 | 0.2504 | 1 |
Trypanosoma cruzi | proton motive ATPase 1, putative | 0.0008 | 0 | 0.5 |
Loa Loa (eye worm) | acetyltransferase | 0.0145 | 1 | 1 |
Leishmania major | P-type H -ATPase, putative | 0.0008 | 0 | 0.5 |
Loa Loa (eye worm) | RNA binding protein | 0.0063 | 0.4022 | 0.4022 |
Mycobacterium ulcerans | metal cation-transporting p-type ATPase CtpC | 0.0008 | 0 | 0.5 |
Mycobacterium ulcerans | metal cation transporter p-type ATPase a | 0.0008 | 0 | 0.5 |
Trypanosoma cruzi | phospholipid-transporting ATPase-like protein, putative | 0.0008 | 0 | 0.5 |
Toxoplasma gondii | histone lysine acetyltransferase GCN5-B | 0.0043 | 0.2504 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.4022 | 0.4022 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0008 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.4022 | 0.4022 |
Mycobacterium leprae | PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB | 0.0008 | 0 | 0.5 |
Trypanosoma cruzi | plasma membrane Ca2+ ATPase | 0.0008 | 0 | 0.5 |
Mycobacterium tuberculosis | Cation transporter P-type ATPase a CtpA | 0.0008 | 0 | 0.5 |
Leishmania major | copper-transporting ATPase-like protein, putative | 0.0008 | 0 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0063 | 0.4022 | 0.4022 |
Trypanosoma brucei | vacuolar-type Ca2+-ATPase, putative | 0.0008 | 0 | 0.5 |
Leishmania major | proton motive ATPase, putative | 0.0008 | 0 | 0.5 |
Chlamydia trachomatis | metal transport ATPase | 0.0008 | 0 | 0.5 |
Schistosoma mansoni | eyes absent homolog | 0.0088 | 0.5837 | 0.5837 |
Brugia malayi | hypothetical protein | 0.0088 | 0.5837 | 0.5837 |
Loa Loa (eye worm) | hypothetical protein | 0.0088 | 0.5837 | 0.5837 |
Echinococcus granulosus | histone acetyltransferase KAT2B | 0.0141 | 0.9702 | 1 |
Echinococcus granulosus | tar DNA binding protein | 0.0063 | 0.4022 | 0.4145 |
Mycobacterium tuberculosis | Probable metal cation transporter P-type ATPase CtpV | 0.0008 | 0 | 0.5 |
Trypanosoma cruzi | copper-transporting ATPase-like protein, putative | 0.0008 | 0 | 0.5 |
Echinococcus multilocularis | tar DNA binding protein | 0.0063 | 0.4022 | 0.4022 |
Mycobacterium ulcerans | metal cation transporter p-type ATPase, CtpV | 0.0008 | 0 | 0.5 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.