Detailed information for compound 800559

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 446.305 | Formula: C19H15IN2OS
  • H donors: 0 H acceptors: 1 LogP: 5.51 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: C=CCN1C(=Nc2ccccc2)S/C(=C/c2ccc(cc2)I)/C1=O
  • InChi: 1S/C19H15IN2OS/c1-2-12-22-18(23)17(13-14-8-10-15(20)11-9-14)24-19(22)21-16-6-4-3-5-7-16/h2-11,13H,1,12H2/b17-13+,21-19+
  • InChiKey: WHFMYQWZAVJVBL-ZFAMVZCKSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi PDZ domain 0.0017 0.0047 0.0049
Brugia malayi RasGEF domain containing protein 0.0017 0.0047 0.0049
Leishmania major hypothetical protein, conserved 0.0029 0.0134 0.0349
Brugia malayi Peripheral plasma membrane protein CASK 0.0017 0.0047 0.0049
Onchocerca volvulus 0.0017 0.0047 0.063
Schistosoma mansoni protein kinase 0.1328 1 1
Mycobacterium ulcerans 4'-phosphopantetheinyl transferase 0.0027 0.0119 0.007
Schistosoma mansoni multidrug resistance protein 0.0012 0.0008 0.0004
Echinococcus multilocularis pdz domain containing protein 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0052 0.031 0.0319
Echinococcus granulosus histone lysine methyltransferase setb 0.002 0.0069 0.0065
Toxoplasma gondii 4'-phosphopantetheinyl transferase domain-containing protein 0.0027 0.0119 0.0306
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Loa Loa (eye worm) PX domain-containing protein 0.0017 0.0047 0.0046
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0036 0.0192 0.0196
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0081 0.0084
Echinococcus multilocularis muscleblind protein 0.0149 0.1052 0.1049
Echinococcus multilocularis L aminoadipate semialdehyde 0.0094 0.0634 0.0631
Loa Loa (eye worm) hypothetical protein 0.0094 0.0634 0.0656
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0008 0.0004
Echinococcus granulosus pdz domain containing protein 0.0017 0.0047 0.0044
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0081 0.008
Schistosoma mansoni hypothetical protein 0.0017 0.0047 0.0044
Schistosoma mansoni hypothetical protein 0.0017 0.0047 0.0044
Schistosoma mansoni cpg binding protein 0.0029 0.0135 0.0132
Schistosoma mansoni multiple pdz domain protein 0.0017 0.0047 0.0044
Schistosoma mansoni cellular tumor antigen P53 0.0049 0.0293 0.0289
Schistosoma mansoni dihydrofolate reductase 0.1278 0.9618 0.9618
Brugia malayi Niemann-Pick C1 protein precursor 0.0099 0.0665 0.0691
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0024 0.0097 0.0048
Brugia malayi Glycosyl hydrolases family 31 protein 0.0163 0.1155 0.1201
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0812 0.6077 0.6076
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0024 0.0097 0.0048
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0134 0.0349
Echinococcus multilocularis Niemann Pick C1 protein 0.0099 0.0665 0.0662
Mycobacterium leprae DIHYDROFOLATE REDUCTASE DFRA (DHFR) (TETRAHYDROFOLATE DEHYDROGENASE) 0.1278 0.9618 1
Schistosoma mansoni multiple pdz domain protein 0.0017 0.0047 0.0044
Brugia malayi Guanylate kinase family protein 0.0017 0.0047 0.0049
Plasmodium falciparum ataxin-2 like protein, putative 0.0029 0.0134 0.0349
Leishmania major dihydrofolate reductase-thymidylate synthase 0.0489 0.3626 1
Brugia malayi 9ORF binding protein 1 0.0017 0.0047 0.0049
Trichomonas vaginalis maltase-glucoamylase, putative 0.0013 0.0019 0.0046
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0081 0.1164
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Echinococcus granulosus syndecan binding protein syntenin 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0081 0.0077
Schistosoma mansoni protein kinase 0.1328 1 1
Schistosoma mansoni hypothetical protein 0.0041 0.0226 0.0223
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0097 0.0246
Loa Loa (eye worm) PDZ-domain-containing protein scribble 0.0017 0.0047 0.0046
Echinococcus granulosus neutral alpha glucosidase AB 0.0036 0.0192 0.0188
Loa Loa (eye worm) hypothetical protein 0.002 0.0069 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0081 0.0084
Loa Loa (eye worm) hypothetical protein 0.0018 0.0051 0.005
Wolbachia endosymbiont of Brugia malayi 4'-phosphopantetheinyl transferase 0.0027 0.0119 0.5
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.002 0.0069 0.0065
Onchocerca volvulus 0.0017 0.0047 0.063
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0081 0.0077
Echinococcus granulosus methyl CpG binding domain protein 2 0.0019 0.0064 0.0061
Schistosoma mansoni hypothetical protein 0.0041 0.0226 0.0223
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0238 0.0234
Schistosoma mansoni hypothetical protein 0.0409 0.3024 0.3022
Brugia malayi hypothetical protein 0.0017 0.0047 0.0049
Schistosoma mansoni cell polarity protein 0.0017 0.0047 0.0044
Echinococcus multilocularis Na(+):H(+) exchange regulatory cofactor NHE RF2 0.0017 0.0047 0.0044
Echinococcus multilocularis pdz domain containing protein 0.0017 0.0047 0.0044
Schistosoma mansoni niemann-pick C1 (NPC1) 0.01 0.0676 0.0673
Trypanosoma brucei glucosidase, putative 0.0036 0.0192 0.0478
Schistosoma mansoni protein kinase C alpha binding protein 0.0017 0.0047 0.0044
Schistosoma mansoni patched 1 0.0042 0.0238 0.0234
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0013 0.0014 0.0011
Brugia malayi PDZ domain containing protein 0.0017 0.0047 0.0049
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0332 0.2439 1
Leishmania major phosphopantetheinyl transferase-like protein 0.0027 0.0119 0.0306
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0238 0.0244
Loa Loa (eye worm) cell junction protein LIN-7 0.0017 0.0047 0.0046
Toxoplasma gondii 4'-phosphopantetheinyl transferase superfamily protein 0.0027 0.0119 0.0306
Brugia malayi PDZ domain containing protein 0.0017 0.0047 0.0049
Brugia malayi PDZ-domain protein scribble 0.0017 0.0047 0.0049
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0081 0.0084
Loa Loa (eye worm) guanylate kinase 0.0017 0.0047 0.0046
Brugia malayi ERG2 and Sigma1 receptor like protein 0.0419 0.3098 0.3221
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0081 0.008
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0081 0.0084
Entamoeba histolytica hypothetical protein 0.0027 0.0119 0.0455
Loa Loa (eye worm) syntrophin-1 0.0017 0.0047 0.0046
Echinococcus granulosus Niemann Pick C1 protein 0.0099 0.0665 0.0662
Loa Loa (eye worm) RasGEF domain-containing protein 0.0017 0.0047 0.0046
Echinococcus multilocularis rho guanine nucleotide exchange factor 12 0.0017 0.0047 0.0044
Schistosoma mansoni multidrug resistance protein 0.0012 0.0008 0.0004
Entamoeba histolytica acyl-coA synthetase, putative 0.0024 0.0097 0.0366
Schistosoma mansoni pdz domain containing protein 0.0017 0.0047 0.0044
Schistosoma mansoni cpg binding protein 0.0033 0.0164 0.0161
Onchocerca volvulus 0.0094 0.0634 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Brugia malayi nuclear hormone receptor 0.0022 0.0081 0.0084
Schistosoma mansoni hypothetical protein 0.0041 0.0226 0.0223
Loa Loa (eye worm) hypothetical protein 0.0237 0.1713 0.1779
Onchocerca volvulus 0.0024 0.0097 0.1422
Brugia malayi gamma-syntrophin-like protein SYN2 0.0017 0.0047 0.0049
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0019 0.0046
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0081 0.0077
Trypanosoma brucei C-8 sterol isomerase, putative 0.0419 0.3098 0.8536
Onchocerca volvulus 0.0017 0.0047 0.063
Echinococcus multilocularis pdz domain containing protein 0.0017 0.0047 0.0044
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0069 0.0444 0.0441
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0081 0.0077
Schistosoma mansoni amyloid beta A4 protein related 0.0017 0.0047 0.0044
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0097 0.0246
Echinococcus multilocularis protein dispatched 1 0.0048 0.0283 0.028
Trypanosoma brucei ISWI complex protein 0.0017 0.0049 0.0082
Schistosoma mansoni microtubule-associated protein tau 0.0691 0.516 0.5158
Entamoeba histolytica hypothetical protein 0.0036 0.019 0.075
Brugia malayi cell junction protein LIN-7 0.0017 0.0047 0.0049
Echinococcus multilocularis MAGUK p55 subfamily 0.0017 0.0047 0.0044
Brugia malayi hypothetical protein 0.0237 0.1713 0.1782
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0036 0.0192 0.0507
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0134 0.0319
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0081 0.0077
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0097 0.0048
Schistosoma mansoni tight junction protein 0.0017 0.0047 0.0044
Loa Loa (eye worm) dihydrofolate reductase 0.1278 0.9618 1
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0081 0.0077
Brugia malayi nuclear receptor RXR 0.0011 0.0004 0.0004
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0097 0.0101
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0192 0.0755
Echinococcus granulosus expressed conserved protein 0.0093 0.0619 0.0616
Brugia malayi Hypothetical 13.5 kDa protein C45G9.7 in chromosome III 0.0017 0.0047 0.0049
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0064 0.0061
Loa Loa (eye worm) hypothetical protein 0.005 0.0297 0.0306
Brugia malayi Neurabin protein 1 0.0017 0.0047 0.0049
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0081 0.0077
Echinococcus multilocularis multiple pdz domain protein 0.0017 0.0047 0.0044
Echinococcus multilocularis multidrug resistance protein 1 0.0012 0.0008 0.0004
Onchocerca volvulus 0.0017 0.0047 0.063
Loa Loa (eye worm) hypothetical protein 0.0149 0.1052 0.109
Brugia malayi Patj homolog 0.0017 0.0047 0.0049
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0081 0.0077
Echinococcus multilocularis syndecan binding protein (syntenin) 0.0017 0.0047 0.0044
Chlamydia trachomatis tail-specific protease 0.0017 0.0047 0.0041
Loa Loa (eye worm) hypothetical protein 0.0099 0.0665 0.0688
Echinococcus granulosus MAGUK p55 subfamily 0.0017 0.0047 0.0044
Schistosoma mansoni PDZ domain protein 0.0017 0.0047 0.0044
Brugia malayi nuclear receptor NHR-88 0.0022 0.0081 0.0084
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0019 0.0046
Echinococcus multilocularis myeloid:lymphoid or mixed lineage leukemia 0.0017 0.0047 0.0044
Onchocerca volvulus Arc homolog 0.0017 0.0047 0.063
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Echinococcus multilocularis 0.0017 0.0047 0.0044
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0008 0.0004
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0192 0.0755
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0004 0.0004
Schistosoma mansoni hypothetical protein 0.0023 0.0095 0.0091
Loa Loa (eye worm) hypothetical protein 0.0012 0.0007 0.0004
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0081 0.008
Schistosoma mansoni bromodomain containing protein 0.0074 0.0475 0.0472
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0018 0.0053 0.0049
Schistosoma mansoni hypothetical protein 0.0017 0.0047 0.0044
Schistosoma mansoni hypothetical protein 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0049 0.0293 0.0301
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0081 0.0084
Treponema pallidum fructose-bisphosphate aldolase 0.0332 0.2439 1
Echinococcus multilocularis neurabin 1 0.0017 0.0047 0.0044
Echinococcus granulosus Niemann Pick C1 protein 0.0141 0.0986 0.0983
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0081 0.0084
Schistosoma mansoni aminoadipate-semialdehyde dehydrogenase 0.0094 0.0634 0.0631
Brugia malayi PHD-finger family protein 0.003 0.0144 0.015
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0081 0.0084
Brugia malayi multidrug resistance protein 3 0.0012 0.0008 0.0008
Loa Loa (eye worm) transcription factor SMAD2 0.0136 0.0947 0.0981
Brugia malayi Domain found in Dishevelled, Egl-10, and Pleckstrin family protein 0.0017 0.0047 0.0049
Loa Loa (eye worm) hypothetical protein 0.0046 0.0268 0.0275
Schistosoma mansoni cell polarity protein 0.0017 0.0047 0.0044
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0008 0.0004
Echinococcus granulosus microtubule associated protein 2 0.0691 0.516 0.5158
Toxoplasma gondii LsmAD domain-containing protein 0.0029 0.0134 0.0349
Schistosoma mansoni ATP-dependent RNA Helicase 0.0017 0.0047 0.0044
Echinococcus multilocularis multiple pdz domain protein 0.0017 0.0047 0.0044
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0332 0.2439 1
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0017 0.0047 0.0044
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0036 0.019 0.0187
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0017 0.0047 0.0044
Plasmodium falciparum bifunctional dihydrofolate reductase-thymidylate synthase 0.0489 0.3626 1
Echinococcus granulosus 3'partial|membrane associated guanylate kinase ww and pdz 0.0017 0.0047 0.0044
Chlamydia trachomatis dihydrofolate reductase 0.1278 0.9618 1
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0097 0.0101
Echinococcus granulosus segment polarity protein dishevelled 0.0017 0.0047 0.0044
Echinococcus multilocularis Partitioning defective 3 protein B 0.0017 0.0047 0.0044
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0017 0.0047 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0081 0.0084
Echinococcus granulosus Rho GTPase activating protein 21 0.0017 0.0047 0.0044
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0081 0.0077
Echinococcus multilocularis disks large 3 0.0017 0.0047 0.0044
Echinococcus multilocularis expressed conserved protein 0.0093 0.0619 0.0616
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0081 0.0077
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0018 0.0053 0.0049
Loa Loa (eye worm) hypothetical protein 0.0022 0.0081 0.008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Brugia malayi Synapse defective protein 1 0.0017 0.0047 0.0049
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0332 0.2439 1
Loa Loa (eye worm) hypothetical protein 0.0018 0.0051 0.005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0017 0.0047 0.0044
Echinococcus granulosus partitioning defective 3 0.0017 0.0047 0.0044
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0041 0.0227 0.0223
Brugia malayi rho guanine nucleotide exchange factor 12 0.0017 0.0047 0.0049
Trypanosoma cruzi ISWI complex protein 0.0017 0.0049 0.0082
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0008 0.0004
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0044 0.0038
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0081 0.0077
Leishmania major glycosyl hydrolase-like protein 0.0013 0.0019 0.0031
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0332 0.2439 1
Plasmodium vivax holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0119 0.0306
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0017 0.0047 0.0044
Echinococcus multilocularis zinc finger protein 0.0024 0.0098 0.0095
Echinococcus multilocularis PDZ domain containing protein GIPC3 0.0017 0.0047 0.0044
Echinococcus granulosus muscleblind protein 0.0149 0.1052 0.1049
Echinococcus multilocularis protein lin 7 B 0.0017 0.0047 0.0044
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0081 0.0084
Schistosoma mansoni lin-7-like proteins 0.0017 0.0047 0.0044
Echinococcus granulosus zinc finger protein 0.0024 0.0098 0.0095
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0238 0.0234
Trichomonas vaginalis maltase-glucoamylase, putative 0.0036 0.0192 0.0755
Echinococcus granulosus pdz domain containing protein 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0018 0.0051 0.005
Brugia malayi hypothetical protein 0.0017 0.0047 0.0049
Echinococcus multilocularis MAGUK p55 subfamily 0.0017 0.0047 0.0044
Echinococcus granulosus PRKCA binding protein 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Loa Loa (eye worm) MH2 domain-containing protein 0.0136 0.0947 0.0981
Echinococcus granulosus Partitioning defective 3 protein B 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.008 0.0527 0.0545
Plasmodium vivax acyl-CoA synthetase, putative 0.0018 0.0051 0.012
Echinococcus multilocularis disks large 1 0.0017 0.0047 0.0044
Brugia malayi MH2 domain containing protein 0.0136 0.0947 0.0985
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Trypanosoma brucei dihydrofolate reductase-thymidylate synthase 0.0489 0.3626 1
Schistosoma mansoni hypothetical protein 0.0041 0.0226 0.0223
Brugia malayi Abnormal embryonic partitioning of cytoplasm protein 3 0.0017 0.0047 0.0049
Onchocerca volvulus Uncharacterized family 31 glucosidase KIAA1161 homolog 0.0013 0.0019 0.0179
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0018 0.0053 0.0049
Echinococcus multilocularis glutamate receptor interacting protein 1 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0022 0.0081 0.008
Echinococcus granulosus amyloid beta A4 protein 0.0017 0.0047 0.0044
Echinococcus multilocularis Rho GTPase activating protein 21 0.0017 0.0047 0.0044
Echinococcus multilocularis partitioning defective 3 0.0017 0.0047 0.0044
Echinococcus multilocularis segment polarity protein dishevelled 0.0017 0.0047 0.0044
Schistosoma mansoni hypothetical protein 0.0017 0.0047 0.0044
Echinococcus granulosus MAGUK p55 subfamily 0.0017 0.0047 0.0044
Echinococcus granulosus multiple pdz domain protein 0.0017 0.0047 0.0044
Echinococcus multilocularis ligand of numb protein x 2 0.0017 0.0047 0.0044
Brugia malayi aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase 0.0094 0.0634 0.0659
Echinococcus multilocularis amyloid beta A4 protein 0.0017 0.0047 0.0044
Echinococcus multilocularis microtubule associated protein 2 0.0691 0.516 0.5158
Echinococcus granulosus multiple pdz domain protein 0.0017 0.0047 0.0044
Echinococcus granulosus survival motor neuron protein 1 0.0237 0.1713 0.171
Echinococcus multilocularis microtubule associated serine:threonine protein 0.0017 0.0047 0.0044
Echinococcus multilocularis Niemann Pick C1 protein 0.0141 0.0986 0.0983
Schistosoma mansoni zinc finger protein 0.0024 0.0098 0.0095
Echinococcus granulosus bromodomain adjacent to zinc finger domain 0.0069 0.0444 0.0441
Brugia malayi Shank2E 0.0017 0.0047 0.0049
Echinococcus multilocularis dual specificity testis specific protein kinase 0.1328 1 1
Schistosoma mansoni sap-97 0.0017 0.0047 0.0044
Schistosoma mansoni sh3 and multiple ankyrin repeat domains protein 12 (shank12) 0.0017 0.0047 0.0044
Echinococcus multilocularis membrane associated guanylate kinase ww and pdz 0.0017 0.0047 0.0044
Schistosoma mansoni hypothetical protein 0.0017 0.0047 0.0044
Echinococcus granulosus peripheral plasma membrane protein CASK 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.1155 0.1152
Mycobacterium ulcerans phosphopantetheinyl transferase, PptII 0.0027 0.0119 0.007
Echinococcus granulosus MAGUK p55 subfamily 0.0017 0.0047 0.0044
Entamoeba histolytica hypothetical protein 0.0036 0.019 0.075
Echinococcus granulosus L aminoadipate semialdehyde 0.0094 0.0634 0.0631
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0081 0.0077
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0017 0.0047 0.0044
Schistosoma mansoni syntenin 0.0017 0.0047 0.0044
Schistosoma mansoni maguk P55 subfamily member 26 0.0017 0.0047 0.0044
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0081 0.0084
Brugia malayi Bromodomain containing protein 0.0087 0.0576 0.0599
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0238 0.0234
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0013 0.0014 0.0011
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0081 0.0077
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0192 0.0755
Loa Loa (eye worm) ATP-binding cassette sub-family B member 2 0.0012 0.0008 0.0005
Leishmania major 4-coumarate:coa ligase-like protein 0.0024 0.0097 0.0246
Echinococcus granulosus beta 1 syntrophin 0.0017 0.0047 0.0044
Onchocerca volvulus 0.0048 0.0283 0.4397
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0024 0.0097 0.0093
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0081 0.0077
Schistosoma mansoni zinc finger protein 0.0017 0.0049 0.0045
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.002 0.0069 0.0065
Brugia malayi AMP-binding enzyme family protein 0.0024 0.0097 0.0101
Schistosoma mansoni multiple pdz domain protein 0.0017 0.0047 0.0044
Echinococcus granulosus dihydrofolate reductase 0.1278 0.9618 0.9618
Echinococcus granulosus rho guanine nucleotide exchange factor 12 0.0017 0.0047 0.0044
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Echinococcus granulosus partitioning defective 3 0.0017 0.0047 0.0044
Schistosoma mansoni alpha-glucosidase 0.014 0.0982 0.0979
Echinococcus multilocularis glutamate receptor interacting protein 1 0.0017 0.0047 0.0044
Mycobacterium leprae conserved hypothetical protein 0.0027 0.0119 0.0023
Schistosoma mansoni alpha-glucosidase 0.014 0.0982 0.0979
Echinococcus multilocularis MAGUK p55 subfamily 0.0017 0.0047 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0192 0.0478
Schistosoma mansoni multiple pdz domain protein 0.0017 0.0047 0.0044
Schistosoma mansoni leucine-rich repeat protein 0.0017 0.0047 0.0044
Brugia malayi hypothetical protein 0.0029 0.0134 0.014
Mycobacterium tuberculosis holo-[acyl-carrier protein] synthase AcpS (holo-ACP synthase) (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrie 0.0027 0.0119 0.0115
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0024 0.0097 0.0048
Onchocerca volvulus 0.0017 0.0047 0.063
Echinococcus multilocularis dnaJ subfamily B 0.0409 0.3024 0.3022
Loa Loa (eye worm) hypothetical protein 0.0018 0.0051 0.005
Echinococcus multilocularis neutral alpha glucosidase AB 0.0036 0.0192 0.0188
Echinococcus multilocularis bromodomain adjacent to zinc finger domain 0.0041 0.0227 0.0223
Schistosoma mansoni Patj homolog 0.0017 0.0047 0.0044
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0081 0.0077
Onchocerca volvulus 0.0094 0.0633 0.9977
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Onchocerca volvulus 0.0022 0.0081 0.1164
Onchocerca volvulus Big bang homolog 0.0017 0.0047 0.063
Giardia lamblia Fructose-bisphosphate aldolase 0.0332 0.2439 0.5
Entamoeba histolytica hypothetical protein 0.0036 0.019 0.075
Echinococcus granulosus tumor protein p63 0.0338 0.2484 0.2481
Brugia malayi CHE-14 protein 0.0042 0.0238 0.0247
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0081 0.0077
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0192 0.0755
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0081 0.0077
Echinococcus multilocularis ATP binding cassette sub family B 0.0012 0.0007 0.0003
Schistosoma mansoni hypothetical protein 0.0017 0.0047 0.0044
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0081 0.0077
Schistosoma mansoni dishevelled 0.0017 0.0047 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0238 0.0946
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0061 0.038 0.0376
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0044 0.0038
Loa Loa (eye worm) hypothetical protein 0.0022 0.0081 0.008
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0036 0.0192 0.0755
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0044 0.0038
Loa Loa (eye worm) hypothetical protein 0.0013 0.0019 0.0016
Echinococcus multilocularis multiple pdz domain protein 0.0017 0.0047 0.0044
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0018 0.0051 0.0045
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0097 0.0048
Loa Loa (eye worm) hypothetical protein 0.0419 0.3098 0.3219
Brugia malayi ABC transporter family protein 0.0012 0.0008 0.0008
Loa Loa (eye worm) multidrug resistance protein 3 0.0012 0.0008 0.0005
Loa Loa (eye worm) hypothetical protein 0.0022 0.0081 0.008
Schistosoma mansoni maguk P55 subfamily member 35 0.0017 0.0047 0.0044
Echinococcus multilocularis C2 calcium dependent membrane targeting 0.0017 0.0047 0.0044
Toxoplasma gondii bifunctional dihydrofolate reductase-thymidylate synthase 0.0489 0.3626 1
Brugia malayi hypothetical protein 0.0011 0.0004 0.0004
Echinococcus granulosus pdz domain containing protein 0.0017 0.0047 0.0044
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0081 0.1164
Echinococcus multilocularis tyrosine protein phosphatase non receptor type 0.0017 0.0047 0.0044
Brugia malayi hypothetical protein 0.0017 0.0047 0.0049
Schistosoma mansoni MAGUK homolog 0.0017 0.0047 0.0044
Echinococcus multilocularis protein patched 0.0042 0.0238 0.0234
Schistosoma mansoni syntrophin 0.0017 0.0047 0.0044
Trichomonas vaginalis sucrase-isomaltase, putative 0.0036 0.0192 0.0755
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0081 0.0077
Loa Loa (eye worm) PHD-finger family protein 0.0023 0.0095 0.0095
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0008 0.0004
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Schistosoma mansoni rab3 interacting molecule (rim)-related 0.0017 0.0047 0.0044
Brugia malayi Protein-tyrosine phosphatase 1 0.0017 0.0047 0.0049
Echinococcus multilocularis membrane associated guanylate kinase, WW and PDZ 0.0017 0.0047 0.0044
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0004 0.0004
Mycobacterium ulcerans acyl-CoA synthetase 0.0024 0.0097 0.0048
Plasmodium vivax bifunctional dihydrofolate reductase-thymidylate synthase, putative 0.0489 0.3626 1
Brugia malayi DIX domain containing protein 0.0017 0.0047 0.0049
Schistosoma mansoni hypothetical protein 0.0017 0.0049 0.0045
Echinococcus granulosus tyrosine protein phosphatase non receptor type 0.0017 0.0047 0.0044
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0036 0.0192 0.0755
Echinococcus multilocularis methyl CpG binding domain protein 2 0.0019 0.0064 0.0061
Brugia malayi Muscleblind-like protein 0.0149 0.1052 0.1094
Schistosoma mansoni hypothetical protein 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Schistosoma mansoni hypothetical protein 0.0017 0.0047 0.0044
Plasmodium vivax ataxin-2 like protein, putative 0.0029 0.0134 0.0349
Echinococcus granulosus glutamate receptor interacting protein 1 0.0017 0.0047 0.0044
Schistosoma mansoni lim domain 0.0018 0.0053 0.0049
Schistosoma mansoni cell polarity protein 0.0017 0.0047 0.0044
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0081 0.0077
Schistosoma mansoni leucine-rich repeat protein 0.0017 0.0047 0.0044
Chlamydia trachomatis holo [acyl-carrier protein] synthase 0.0027 0.0119 0.0115
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0018 0.0051 0.0045
Brugia malayi Partitioning defective-6 homolog alpha 0.0017 0.0047 0.0049
Mycobacterium tuberculosis Dihydrofolate reductase DfrA (DHFR) (tetrahydrofolate dehydrogenase) 0.1278 0.9618 1
Loa Loa (eye worm) hypothetical protein 0.0149 0.1052 0.109
Schistosoma mansoni pdz domain containing protein 0.0017 0.0047 0.0044
Echinococcus multilocularis partitioning defective 3 0.0017 0.0047 0.0044
Brugia malayi Ferm domain 0.0017 0.0047 0.0049
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0081 0.0084
Loa Loa (eye worm) peripheral plasma membrane protein CASK 0.0017 0.0047 0.0046
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0013 0.0019 0.0046
Echinococcus multilocularis lysosomal alpha glucosidase 0.0163 0.1155 0.1152
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0008 0.0004
Loa Loa (eye worm) guanylate kinase 0.0017 0.0047 0.0046
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0081 0.0077
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Echinococcus granulosus myeloid:lymphoid or mixed lineage leukemia 0.0017 0.0047 0.0044
Echinococcus granulosus Microtubule-associated serine/threonine-protein kinase 0.0017 0.0047 0.0044
Brugia malayi CXXC zinc finger family protein 0.0029 0.0135 0.014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Echinococcus granulosus tight junction protein ZO 3 0.0017 0.0047 0.0044
Echinococcus granulosus membrane associated guanylate kinase, WW and PDZ 0.0017 0.0047 0.0044
Echinococcus multilocularis beta 1 syntrophin 0.0017 0.0047 0.0044
Trypanosoma cruzi PAB1-binding protein , putative 0.0029 0.0134 0.0319
Plasmodium falciparum holo-[acyl-carrier-protein] synthase, putative 0.0027 0.0119 0.0306
Schistosoma mansoni smdr2 0.0012 0.0008 0.0004
Echinococcus multilocularis multidrug resistance protein 1 0.0012 0.0008 0.0004
Brugia malayi Glycosyl hydrolases family 31 protein 0.0036 0.0192 0.0199
Echinococcus multilocularis SH3 and multiple ankyrin repeat domains protein 0.0017 0.0047 0.0044
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0081 0.0077
Loa Loa (eye worm) X11 protein 0.0017 0.0047 0.0046
Trypanosoma cruzi dihydrofolate reductase-thymidylate synthase 0.0489 0.3626 1
Brugia malayi syntenin 0.0017 0.0047 0.0049
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Echinococcus granulosus disks large 1 0.0017 0.0047 0.0044
Echinococcus granulosus lysosomal alpha glucosidase 0.0163 0.1155 0.1152
Brugia malayi Syntrophin-1 0.0017 0.0047 0.0049
Loa Loa (eye worm) protein-tyrosine phosphatase 1 0.0017 0.0047 0.0046
Leishmania major hypothetical protein, conserved 0.0017 0.0049 0.0113
Schistosoma mansoni afadin (af-6 protein) 0.0017 0.0047 0.0044
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0081 0.0077
Brugia malayi interleukin-16 0.0017 0.0047 0.0049
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0017 0.0047 0.0044
Onchocerca volvulus 0.0017 0.0047 0.063
Schistosoma mansoni hypothetical protein 0.0048 0.0283 0.028
Brugia malayi microtubule-associated serine/threonine protein kinase 2 (MAST2) 0.0017 0.0047 0.0049
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0332 0.2439 1
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0332 0.2439 1
Schistosoma mansoni transcription factor LCR-F1 0.0036 0.019 0.0187
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0081 0.1164
Echinococcus multilocularis tight junction protein ZO 3 0.0017 0.0047 0.0044
Brugia malayi protein kinase C-binding protein PICK1 0.0017 0.0047 0.0049
Schistosoma mansoni discs large 0.0017 0.0047 0.0044
Echinococcus multilocularis fetal alzheimer antigen, falz 0.0027 0.0124 0.012
Trypanosoma cruzi ISWI complex protein 0.0017 0.0049 0.0082
Loa Loa (eye worm) DIX domain-containing protein 0.0017 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0029 0.0134 0.0136
Brugia malayi ecdysteroid receptor 0.0022 0.0081 0.0084
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0192 0.0755
Brugia malayi hypothetical protein 0.0017 0.0047 0.0049
Trypanosoma brucei hypothetical protein, conserved 0.0027 0.0119 0.0276
Echinococcus granulosus cell polarity protein 0.0017 0.0047 0.0044
Schistosoma mansoni thyroid hormone receptor 0.0022 0.0081 0.0077
Brugia malayi Guanylate kinase family protein 0.0017 0.0047 0.0049
Loa Loa (eye worm) hypothetical protein 0.0214 0.1543 0.1601
Echinococcus multilocularis pdz domain containing protein 0.0017 0.0047 0.0044
Echinococcus granulosus dnaJ subfamily B 0.0409 0.3024 0.3022
Mycobacterium ulcerans dihydrofolate reductase DfrA 0.1278 0.9618 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Echinococcus multilocularis protein piccolo 0.0017 0.0047 0.0044
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0008 0.0004
Echinococcus granulosus ligand of numb protein x 2 0.0017 0.0047 0.0044
Schistosoma mansoni multidrug resistance protein 0.0012 0.0008 0.0004
Schistosoma mansoni methyl-cpg binding protein mbd 0.0019 0.0064 0.0061
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0162 0.1149 0.1105
Echinococcus multilocularis partitioning defective protein 6 0.0017 0.0047 0.0044
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0019 0.0046
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0081 0.0084
Loa Loa (eye worm) AGC/MAST/MAST protein kinase 0.0017 0.0047 0.0046
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0012 0.0008 0.0005
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0081 0.0077
Echinococcus granulosus C2 calcium dependent membrane targeting 0.0017 0.0047 0.0044
Schistosoma mansoni hypothetical protein 0.0013 0.0014 0.0011
Brugia malayi hypothetical protein 0.0017 0.0047 0.0049
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0192 0.0755
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0081 0.0077
Echinococcus multilocularis muscleblind protein 1 0.0149 0.1052 0.1049
Plasmodium falciparum acyl-CoA synthetase 0.0018 0.0051 0.012
Echinococcus granulosus Na:H exchange regulatory cofactor NHE RF2 0.0017 0.0047 0.0044
Loa Loa (eye worm) 9ORF binding protein 1 0.0017 0.0047 0.0046
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0081 0.0077
Brugia malayi Dihydrofolate reductase 0.1278 0.9618 1
Brugia malayi hypothetical protein 0.0011 0.0004 0.0004
Trypanosoma brucei PAB1-binding protein , putative 0.0029 0.0134 0.0319
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0332 0.2439 1
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0097 0.0366
Echinococcus granulosus disks large 3 0.0017 0.0047 0.0044
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0008 0.0004
Echinococcus multilocularis tumor protein p63 0.0338 0.2484 0.2481
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0024 0.0097 0.0093
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0024 0.0097 0.0048
Brugia malayi PDZ domain containing protein 0.0017 0.0047 0.0049
Onchocerca volvulus 0.0029 0.0135 0.2029
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0081 0.0084
Onchocerca volvulus 0.0017 0.0047 0.063
Loa Loa (eye worm) PDZ domain-containing protein 0.0017 0.0047 0.0046
Echinococcus granulosus neurabin 1 0.0017 0.0047 0.0044
Echinococcus granulosus 55 kDa erythrocyte membrane protein 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0022 0.0081 0.008
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0163 0.1155 0.1197
Entamoeba histolytica hypothetical protein 0.0036 0.019 0.075
Loa Loa (eye worm) hypothetical protein 0.0044 0.0248 0.0254
Echinococcus multilocularis cell polarity protein leucine rich repeat 0.0017 0.0047 0.0044
Echinococcus granulosus pdz domain containing protein 0.0017 0.0047 0.0044
Leishmania major C-8 sterol isomerase-like protein 0.0419 0.3098 0.854
Mycobacterium ulcerans hypothetical protein 0.0024 0.0097 0.0048
Schistosoma mansoni regulator of G protein signaling 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0022 0.0081 0.008
Trichomonas vaginalis alpha-glucosidase, putative 0.0036 0.0192 0.0755
Schistosoma mansoni multiple pdz domain protein 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0042 0.0238 0.0244
Echinococcus multilocularis survival motor neuron protein 1 0.0237 0.1713 0.171
Loa Loa (eye worm) hypothetical protein 0.0022 0.0081 0.008
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0008 0.0004
Echinococcus granulosus protein lin 7 B 0.0017 0.0047 0.0044
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0081 0.0077
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0019 0.0046
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0019 0.0046
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0135 0.0137
Echinococcus granulosus multidrug resistance protein 1 0.0012 0.0008 0.0004
Schistosoma mansoni alpha glucosidase 0.0036 0.0192 0.0188
Schistosoma mansoni hypothetical protein 0.0017 0.0047 0.0044
Schistosoma mansoni hypothetical protein 0.0036 0.019 0.0187
Echinococcus multilocularis ATP binding cassette subfamily B (MDR:TAP) 0.0012 0.0008 0.0004
Onchocerca volvulus 0.0017 0.0047 0.063
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0013 0.0019 0.0046
Loa Loa (eye worm) PAR-6 protein 0.0017 0.0047 0.0046
Echinococcus multilocularis peripheral plasma membrane protein CASK 0.0017 0.0047 0.0044
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0081 0.008
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Schistosoma mansoni survival motor neuron protein 0.0048 0.0283 0.028
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0081 0.008
Loa Loa (eye worm) bromodomain containing protein 0.002 0.0069 0.0068
Brugia malayi hypothetical protein 0.0018 0.0057 0.006
Brugia malayi Glycosyl hydrolases family 31 protein 0.0013 0.0019 0.002
Schistosoma mansoni pdz and lim domain protein 0.0018 0.0053 0.0049
Brugia malayi hypothetical protein 0.0017 0.0047 0.0049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0332 0.2439 1
Loa Loa (eye worm) gopc protein 0.0017 0.0047 0.0046
Echinococcus multilocularis dihydrofolate reductase 0.1278 0.9618 0.9618
Schistosoma mansoni cell polarity protein 0.0017 0.0047 0.0044
Brugia malayi hypothetical protein 0.0036 0.019 0.0198
Brugia malayi abnormal cell lineage protein 10 (Protein lin-10), putative 0.0017 0.0047 0.0049
Schistosoma mansoni dishevelled 0.0017 0.0047 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.002 0.0069 0.0065
Echinococcus granulosus segment polarity protein dishevelled 0.0017 0.0047 0.0044
Echinococcus granulosus ATP binding cassette subfamily B MDR:TAP 0.0012 0.0008 0.0004
Brugia malayi Bromodomain containing protein 0.0044 0.0247 0.0257
Entamoeba histolytica acyl-CoA synthetase, putative 0.0024 0.0097 0.0366
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0081 0.0084
Schistosoma mansoni cpg binding protein 0.0033 0.0164 0.0161
Brugia malayi steroid hormone receptor 0.0022 0.0081 0.0084
Onchocerca volvulus 0.0017 0.0047 0.063
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0081 0.008
Trypanosoma cruzi C-8 sterol isomerase, putative 0.0419 0.3098 0.8536
Brugia malayi gopc protein 0.0017 0.0047 0.0049
Onchocerca volvulus 0.0017 0.0047 0.063
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Loa Loa (eye worm) hypothetical protein 0.0018 0.0051 0.005
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0081 0.008
Echinococcus multilocularis PDZ and LIM domain protein Zasp 0.0017 0.0047 0.0044
Echinococcus granulosus fetal alzheimer antigen falz 0.0027 0.0124 0.012
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0017 0.0047 0.0044
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0192 0.0478
Brugia malayi PDZ domain containing protein 0.0017 0.0047 0.0049
Loa Loa (eye worm) hypothetical protein 0.0024 0.0097 0.0097
Trichomonas vaginalis alpha-glucosidase, putative 0.0013 0.0019 0.0046
Loa Loa (eye worm) hypothetical protein 0.0022 0.0081 0.008
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0162 0.1149 0.1187
Brugia malayi PDZ domain 0.0017 0.0047 0.0049
Echinococcus multilocularis PRKCA binding protein 0.0017 0.0047 0.0044
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0162 0.1149 0.1147
Schistosoma mansoni discs lost-related 0.0017 0.0047 0.0044
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Brugia malayi C2 domain containing protein 0.0017 0.0047 0.0049
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0017 0.0047 0.0044
Schistosoma mansoni MAGUK homolog 0.0017 0.0047 0.0044
Echinococcus granulosus 5'partial|ATP binding cassette sub family B 0.0012 0.0007 0.0003
Echinococcus multilocularis segment polarity protein dishevelled 0.0017 0.0047 0.0044
Echinococcus multilocularis thyroid hormone receptor alpha 0.0022 0.0081 0.0077
Schistosoma mansoni hypothetical protein 0.0017 0.0047 0.0044
Leishmania major alpha glucosidase II subunit, putative 0.0036 0.0192 0.0507
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0048 0.0283 0.0295
Echinococcus granulosus multiple pdz domain protein 0.0017 0.0047 0.0044
Echinococcus multilocularis 55 kDa erythrocyte membrane protein 0.0017 0.0047 0.0044
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0036 0.019 0.0187
Echinococcus granulosus PDZ and LIM domain protein Zasp 0.0018 0.0053 0.0049
Schistosoma mansoni acetyl-CoA C-acetyltransferase 0.0027 0.0124 0.012
Schistosoma mansoni hypothetical protein 0.0017 0.0047 0.0044
Echinococcus granulosus SH3 and multiple ankyrin repeat domains protein 0.0017 0.0047 0.0044
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0017 0.0044 0.0038
Brugia malayi PX domain containing protein 0.0017 0.0047 0.0049
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0351 0.0947
Onchocerca volvulus Segment polarity protein dishevelled homolog 0.0017 0.0047 0.063
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046
Brugia malayi dihydrofolate reductase family protein 0.1278 0.9618 1
Echinococcus granulosus cpg binding protein 0.0033 0.0164 0.0161
Echinococcus multilocularis cpg binding protein 0.0033 0.0164 0.0161
Onchocerca volvulus 0.0017 0.0047 0.063
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0332 0.2439 1
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0081 0.0084
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0081 0.008
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0081 0.0084
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0081 0.0077
Onchocerca volvulus 0.0049 0.0293 0.4545
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0099 0.0665 0.2702
Schistosoma mansoni coup transcription factor 0.0022 0.0081 0.0077
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0332 0.2439 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0047 0.0046

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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