TDR Targets

Basic information

Technical information

TDR Targets ID: 800578
Name: 1-(2-ethylsulfonylethyl)piperidine
MW: 205.318 | Formula: C9H19NO2S
H donors: 0 H acceptors: 2 LogP: 0.85 Rotable bonds: 4
Rule of 5 violations (Lipinski): 1
SMILES: CCS(=O)(=O)CCN1CCCCC1
InChi: 1S/C9H19NO2S/c1-2-13(11,12)9-8-10-6-4-3-5-7-10/h2-9H2,1H3
InChiKey: XXWMLROCVKLNOU-UHFFFAOYSA-N

Network

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Target Layer

Model Organisms

Species	Viewmode
Arabidopsis thaliana
Caenorhabditis elegans
Dictyostelium discoideum
Drosophila melanogaster
Escherichia coli
Homo sapiens
Mus musculus
Oryza sativa
Saccharomyces cerevisiae
Schmidtea mediterranea
Other organisms

TDR Pathogens:

Species	Viewmode
Brugia malayi
Chlamydia trachomatis
Echinococcus granulosus
Entamoeba histolytica
Echinococcus multilocularis
Giardia lamblia
Leishmania major
Loa Loa (eye worm)
Mycobacterium leprae
Mycobacterium tuberculosis
Mycobacterium ulcerans
Onchocerca volvulus
Plasmodium falciparum
Plasmodium vivax
Schistosoma mansoni
Trypanosoma brucei
Trypanosoma cruzi
Toxoplasma gondii
Treponema pallidum
Trichomonas vaginalis
Wolbachia endosymbiont of Brugia malayi

Other Pathogens:

Species	Viewmode
Babesia bovis
Candida albicans
Cryptosporidium hominis
Cryptosporidium parvum
Leishmania braziliensis
Leishmania donovani
Leishmania infantum
Leishmania mexicana
Neospora caninum
Plasmodium berghei
Plasmodium knowlesi
Plasmodium yoelii
Schistosoma japonicum
Trypanosoma brucei gambiense
Trypanosoma congolense
Theileria parva

Compound Layer

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Clustering layers

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Synonyms

Oprea1_165742
1-(2-Ethanesulfonyl-ethyl)-piperidine
BAS 00392694
Oprea1_116688
ZERO/005701

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology

No druggable targets predicted by orthology data

By sequence similarity to non orthologous known druggable targets

No druggable targets predicted by sequence similarity

Ranking Plot

Putative Targets List

Species	Potential target	Raw	Global	Species
Echinococcus granulosus	uncharacterized sodium dependent transporter	0.0098	0.0915	0.0915
Mycobacterium tuberculosis	Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI)	0.0058	0.0385	0.5
Chlamydia trachomatis	Ssodium-dependent amino acid transporter	0.0098	0.0915	1
Treponema pallidum	sodium- and chloride- dependent transporter	0.0576	0.7245	1
Brugia malayi	hypothetical protein	0.0226	0.2611	0.2594
Brugia malayi	aryl hydrocarbon receptor AHR-1	0.0039	0.0131	0.0108
Trypanosoma cruzi	ISWI complex protein	0.0049	0.0269	0.6883
Loa Loa (eye worm)	hypothetical protein	0.0061	0.0429	0.0415
Trichomonas vaginalis	ap endonuclease, putative	0.0058	0.0385	0.135
Toxoplasma gondii	PHD-finger domain-containing protein	0.0061	0.0429	0.4555
Brugia malayi	Helix-loop-helix DNA-binding domain containing protein	0.0039	0.0138	0.0115
Echinococcus multilocularis	transfer RNA-Lys	0.0038	0.0119	0.0097
Plasmodium vivax	hypothetical protein, conserved	0.0061	0.0429	0.4555
Loa Loa (eye worm)	helix-loop-helix DNA-binding domain-containing protein	0.0039	0.0138	0.0123
Plasmodium vivax	AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative	0.0058	0.0385	0.4058
Echinococcus multilocularis	cadherin EGF LAG seven pass G type receptor	0.0066	0.0498	0.0476
Loa Loa (eye worm)	hypothetical protein	0.0098	0.0915	0.0901
Echinococcus granulosus	fetal alzheimer antigen falz	0.0074	0.0598	0.0598
Onchocerca volvulus		0.0098	0.0915	0.1235
Loa Loa (eye worm)	hypothetical protein	0.0209	0.2393	0.2382
Echinococcus multilocularis	peregrin	0.0069	0.0529	0.0508
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0082	0.0702	0.094
Echinococcus multilocularis	Aryl hydrocarbon receptor nuclear	0.008	0.068	0.0659
Schistosoma mansoni	hypothetical protein	0.0143	0.1516	0.2067
Mycobacterium leprae	Possible regulatory protein	0.003	0.0015	0.5
Brugia malayi	hypothetical protein	0.0039	0.0131	0.0108
Mycobacterium ulcerans	exodeoxyribonuclease III protein XthA	0.0058	0.0385	1
Schistosoma mansoni	mixed-lineage leukemia protein mll	0.0062	0.0439	0.0576
Echinococcus multilocularis	GPCR, family 2	0.0066	0.0498	0.0476
Plasmodium vivax	hypothetical protein, conserved	0.0098	0.0915	1
Echinococcus granulosus	histone lysine methyltransferase setb	0.0085	0.0746	0.0746
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0131	0.0116
Schistosoma mansoni	sodium/chloride dependent transporter	0.0098	0.0915	0.1235
Brugia malayi	Corticotropin releasing factor receptor 2 precursor, putative	0.0209	0.2393	0.2376
Echinococcus multilocularis	muscleblind protein	0.0784	1	1
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.0576	0.7245	1
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0224	0.0279
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0193	0.2174	0.2174
Onchocerca volvulus		0.0098	0.0915	0.1235
Plasmodium vivax	amine transporter, putative	0.0098	0.0915	1
Toxoplasma gondii	Sodium:neurotransmitter symporter family protein	0.0098	0.0915	1
Echinococcus granulosus	cpg binding protein	0.0036	0.0102	0.0102
Schistosoma mansoni	sodium-dependent amino acid transporter	0.0098	0.0915	0.1235
Echinococcus multilocularis	jumonji domain containing protein	0.0085	0.0746	0.0725
Echinococcus granulosus	cadherin EGF LAG seven pass G type receptor	0.0066	0.0498	0.0498
Loa Loa (eye worm)	hypothetical protein	0.0098	0.0915	0.0901
Echinococcus multilocularis	Basic leucine zipper (bZIP) transcription	0.0077	0.0642	0.0621
Echinococcus granulosus	Transcription factor JmjC domain containing protein	0.02	0.2269	0.2269
Brugia malayi	hypothetical protein	0.0039	0.0138	0.0115
Loa Loa (eye worm)	pigment dispersing factor receptor c	0.0209	0.2393	0.2382
Onchocerca volvulus	Alhambra homolog	0.0061	0.0429	0.0563
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.0098	0.0915	0.1235
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0224	0.0224
Echinococcus granulosus	diuretic hormone 44 receptor GPRdih2	0.0066	0.0498	0.0498
Echinococcus granulosus	geminin	0.0169	0.1857	0.1857
Entamoeba histolytica	hypothetical protein	0.0077	0.0642	1
Onchocerca volvulus		0.0038	0.0127	0.0144
Loa Loa (eye worm)	PHD-finger family protein	0.0066	0.0496	0.0482
Brugia malayi	hypothetical protein	0.0077	0.0642	0.0621
Leishmania major	apurinic/apyrimidinic endonuclease-redox protein	0.0058	0.0385	1
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0085	0.0746	0.1002
Echinococcus multilocularis	Transcription factor, JmjC domain containing protein	0.02	0.2269	0.2251
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0098	0.0915	0.0894
Entamoeba histolytica	hypothetical protein	0.0077	0.0642	1
Brugia malayi	jmjC domain containing protein	0.0082	0.0702	0.0681
Loa Loa (eye worm)	transcription factor SMAD2	0.0125	0.1276	0.1263
Loa Loa (eye worm)	hypothetical protein	0.0098	0.0915	0.0901
Toxoplasma gondii	Sodium:neurotransmitter symporter family protein	0.0098	0.0915	1
Echinococcus granulosus	sodium:chloride dependent neurotransmitter	0.0098	0.0915	0.0915
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0224	0.0202
Loa Loa (eye worm)	Sodium:neurotransmitter symporter family protein	0.0098	0.0915	0.0901
Echinococcus granulosus	methyl CpG binding domain protein 2	0.0055	0.0344	0.0344
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease, putative	0.0058	0.0385	1
Echinococcus granulosus	uncharacterized sodium dependent transporter	0.0098	0.0915	0.0915
Loa Loa (eye worm)	hypothetical protein	0.0576	0.7245	0.7241
Schistosoma mansoni	cpg binding protein	0.0036	0.0102	0.011
Plasmodium falciparum	transporter, putative	0.0098	0.0915	1
Loa Loa (eye worm)	hypothetical protein	0.0123	0.1248	0.1235
Brugia malayi	aryl hydrocarbon receptor nuclear translocator protein, putative	0.0089	0.0796	0.0775
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.0098	0.0915	0.1235
Echinococcus granulosus	aryl hydrocarbon receptor	0.0069	0.0532	0.0532
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0115	0.1145	0.1124
Loa Loa (eye worm)	bromodomain containing protein	0.0057	0.037	0.0356
Schistosoma mansoni	bromodomain-containing nuclear protein 1 brd1	0.0061	0.0429	0.0563
Echinococcus multilocularis	fetal alzheimer antigen, falz	0.0074	0.0598	0.0577
Toxoplasma gondii	Sodium:neurotransmitter symporter family protein	0.0098	0.0915	1
Schistosoma mansoni	hypothetical protein	0.0408	0.502	0.6919
Brugia malayi	Bromodomain containing protein	0.0069	0.0529	0.0508
Echinococcus multilocularis	uncharacterized sodium dependent transporter	0.0098	0.0915	0.0894
Brugia malayi	Pre-SET motif family protein	0.0208	0.2376	0.2359
Echinococcus multilocularis	geminin	0.0169	0.1857	0.1839
Loa Loa (eye worm)	hypothetical protein	0.0098	0.0915	0.0901
Echinococcus multilocularis	guanine nucleotide binding protein G(s) subunit	0.0046	0.0224	0.0202
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.0098	0.0915	0.1235
Loa Loa (eye worm)	GTP-binding regulatory protein Gs alpha-S chain	0.0046	0.0224	0.021
Schistosoma mansoni	jumonji/arid domain-containing protein	0.0082	0.0702	0.094
Loa Loa (eye worm)	aryl Hydrocarbon receptor Associated protein family member	0.0119	0.1191	0.1178
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0131	0.0116
Loa Loa (eye worm)	hypothetical protein	0.0066	0.0498	0.0484
Echinococcus granulosus	single minded 2	0.0038	0.0119	0.0119
Loa Loa (eye worm)	serotonin transporter b	0.0576	0.7245	0.7241
Brugia malayi	PAS domain containing protein	0.0067	0.0513	0.0492
Loa Loa (eye worm)	hypoxia-induced factor 1	0.0158	0.1707	0.1695
Echinococcus multilocularis	sodium and chloride dependent glycine	0.0098	0.0915	0.0894
Brugia malayi	exodeoxyribonuclease III family protein	0.0058	0.0385	0.0363
Onchocerca volvulus		0.0068	0.0525	0.0695
Entamoeba histolytica	hypothetical protein	0.0077	0.0642	1
Echinococcus granulosus	DNA apurinic or apyrimidinic site lyase	0.0058	0.0385	0.0385
Schistosoma mansoni	hypothetical protein	0.0169	0.1857	0.254
Loa Loa (eye worm)	hypothetical protein	0.0105	0.1007	0.0994
Trichomonas vaginalis	ap endonuclease, putative	0.0058	0.0385	0.135
Schistosoma mansoni	acetyl-CoA C-acetyltransferase	0.0074	0.0598	0.0797
Echinococcus multilocularis	diuretic hormone 44 receptor GPRdih2	0.0066	0.0498	0.0476
Trypanosoma cruzi	ISWI complex protein	0.0049	0.0269	0.6883
Schistosoma mansoni	hypothetical protein	0.0049	0.0269	0.0341
Loa Loa (eye worm)	hypothetical protein	0.0098	0.0915	0.0901
Toxoplasma gondii	hypothetical protein	0.0098	0.0915	1
Schistosoma mansoni	methyl-cpg binding protein mbd	0.0055	0.0344	0.0444
Brugia malayi	hypothetical protein	0.0098	0.0915	0.0894
Echinococcus multilocularis	DNA (apurinic or apyrimidinic site) lyase	0.0058	0.0385	0.0363
Loa Loa (eye worm)	hypothetical protein	0.0098	0.0915	0.0901
Toxoplasma gondii	hypothetical protein	0.0098	0.0915	1
Brugia malayi	F/Y-rich N-terminus family protein	0.0036	0.0096	0.0073
Brugia malayi	GTP-binding regulatory protein Gs alpha-S chain, putative	0.0046	0.0224	0.0202
Brugia malayi	Calcitonin receptor-like protein seb-1	0.0209	0.2393	0.2376
Brugia malayi	calcium-independent alpha-latrotoxin receptor 2, putative	0.0066	0.0498	0.0476
Echinococcus granulosus	lysine specific demethylase 5A	0.0082	0.0702	0.0702
Plasmodium falciparum	phd finger protein, putative	0.0061	0.0429	0.0835
Echinococcus multilocularis	PHD finger protein rhinoceros	0.0061	0.0429	0.0407
Echinococcus multilocularis	serotonin transporter	0.0576	0.7245	0.7239
Toxoplasma gondii	exonuclease III APE	0.0058	0.0385	0.4058
Schistosoma mansoni	hypothetical protein	0.0061	0.0429	0.0563
Brugia malayi	Bromodomain containing protein	0.0123	0.1245	0.1225
Schistosoma mansoni	sodium-dependent neurotransmitter transporter	0.0098	0.0915	0.1235
Echinococcus granulosus	serotonin transporter	0.0576	0.7245	0.7245
Schistosoma mansoni	hypothetical protein	0.0066	0.0498	0.0658
Onchocerca volvulus		0.0576	0.7245	1
Schistosoma mansoni	jumonji domain containing protein	0.0159	0.1724	0.2356
Brugia malayi	MH2 domain containing protein	0.0125	0.1276	0.1256
Loa Loa (eye worm)	PHD-finger family protein	0.0061	0.0429	0.0415
Echinococcus multilocularis	sodium dependent neurotransmitter transporter	0.0098	0.0915	0.0894
Toxoplasma gondii	histone lysine methyltransferase SET1	0.0063	0.0454	0.483
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0098	0.0915	0.0894
Loa Loa (eye worm)	hypothetical protein	0.0226	0.2611	0.26
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0224	0.0279
Brugia malayi	PHD-finger family protein	0.0061	0.0429	0.0407
Echinococcus granulosus	muscleblind protein	0.0784	1	1
Brugia malayi	jmjC domain containing protein	0.02	0.2269	0.2251
Onchocerca volvulus	Protein cycle homolog	0.0039	0.0138	0.0159
Schistosoma mansoni	single-minded	0.0067	0.0513	0.0679
Schistosoma mansoni	hypothetical protein	0.0066	0.0498	0.0658
Schistosoma mansoni	zinc finger protein	0.0049	0.0269	0.0341
Echinococcus multilocularis	muscleblind protein 1	0.0784	1	1
Echinococcus granulosus	bromodomain adjacent to zinc finger domain	0.0115	0.1145	0.1145
Loa Loa (eye worm)	pre-SET domain-containing protein family protein	0.0208	0.2376	0.2365
Wolbachia endosymbiont of Brugia malayi	exonuclease III	0.0058	0.0385	0.5
Brugia malayi	Sodium:neurotransmitter symporter family protein 1, putative	0.0098	0.0915	0.0894
Schistosoma mansoni	histone-lysine n-methyltransferase setb1	0.0085	0.0746	0.1002
Brugia malayi	Latrophilin receptor protein 2	0.0066	0.0498	0.0476
Leishmania major	hypothetical protein, conserved	0.0049	0.0269	0.6883
Schistosoma mansoni	hypothetical protein	0.0077	0.0642	0.0858
Brugia malayi	hypoxia-induced factor 1	0.0158	0.1707	0.1688
Trypanosoma brucei	apurinic/apyrimidinic endonuclease, putative	0.0058	0.0385	1
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0576	0.7245	0.7239
Toxoplasma gondii	PHD-finger domain-containing protein	0.0061	0.0429	0.4555
Schistosoma mansoni	aryl hydrocarbon receptor nuclear translocator homolog (darnt)	0.0089	0.0796	0.1071
Schistosoma mansoni	ap endonuclease	0.0058	0.0385	0.0501
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0131	0.0116
Entamoeba histolytica	hypothetical protein	0.0077	0.0642	1
Echinococcus granulosus	sodium and chloride dependent glycine	0.0098	0.0915	0.0915
Schistosoma mansoni	norepinephrine/norepinephrine transporter	0.0098	0.0915	0.1235
Loa Loa (eye worm)	jmjC domain-containing protein	0.0126	0.129	0.1277
Schistosoma mansoni	cpg binding protein	0.0036	0.0102	0.011
Schistosoma mansoni	bromodomain containing protein	0.0204	0.2326	0.319
Schistosoma mansoni	zinc finger protein	0.0064	0.0472	0.0623
Echinococcus granulosus	guanine nucleotide binding protein Gs subunit	0.0046	0.0224	0.0224
Schistosoma mansoni	ap endonuclease	0.0058	0.0385	0.0501
Loa Loa (eye worm)	hypothetical protein	0.0085	0.0746	0.0733
Echinococcus granulosus	peregrin	0.0069	0.0529	0.0529
Schistosoma mansoni	Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein)	0.0046	0.0224	0.0279
Loa Loa (eye worm)	hypothetical protein	0.0784	1	1
Echinococcus granulosus	PHD finger protein rhinoceros	0.0061	0.0429	0.0429
Schistosoma mansoni	sodium/chloride dependent transporter	0.0098	0.0915	0.1235
Loa Loa (eye worm)	hypothetical protein	0.0576	0.7245	0.7241
Loa Loa (eye worm)	MH2 domain-containing protein	0.0125	0.1276	0.1263
Loa Loa (eye worm)	latrophilin receptor protein 2	0.0066	0.0498	0.0484
Echinococcus multilocularis	bromodomain adjacent to zinc finger domain	0.0193	0.2174	0.2157
Brugia malayi	Bromodomain containing protein	0.0242	0.2823	0.2807
Echinococcus multilocularis	aryl hydrocarbon receptor	0.0069	0.0532	0.051
Loa Loa (eye worm)	hypothetical protein	0.0131	0.1348	0.1336
Schistosoma mansoni	transcription factor LCR-F1	0.0077	0.0642	0.0858
Giardia lamblia	PHD finger protein 15	0.0061	0.0429	1
Schistosoma mansoni	aryl hydrocarbon receptor	0.0068	0.0521	0.0689
Echinococcus multilocularis	sodium and chloride dependent glycine	0.0098	0.0915	0.0894
Loa Loa (eye worm)	Sodium:neurotransmitter symporter family protein	0.0098	0.0915	0.0901
Echinococcus granulosus	zinc finger protein	0.0064	0.0472	0.0472
Onchocerca volvulus		0.0237	0.2756	0.3784
Echinococcus multilocularis	sodium:chloride dependent neurotransmitter	0.0098	0.0915	0.0894
Echinococcus multilocularis	lysine specific demethylase 5A	0.0074	0.0599	0.0578
Echinococcus granulosus	Basic leucine zipper bZIP transcription	0.0077	0.0642	0.0642
Echinococcus multilocularis	dnaJ subfamily B	0.0408	0.502	0.5009
Loa Loa (eye worm)	hypothetical protein	0.0098	0.0915	0.0901
Loa Loa (eye worm)	exodeoxyribonuclease III family protein	0.0058	0.0385	0.0371
Schistosoma mansoni	sodium-dependent neurotransmitter transporter	0.0098	0.0915	0.1235
Schistosoma mansoni	sodium/chloride dependent neurotransmitter transporter	0.0098	0.0915	0.1235
Onchocerca volvulus		0.0098	0.0915	0.1235
Loa Loa (eye worm)	solute carrier family 6 member 4	0.0576	0.7245	0.7241
Schistosoma mansoni	hypothetical protein	0.0066	0.0498	0.0658
Brugia malayi	Sodium:neurotransmitter symporter family protein	0.0098	0.0915	0.0894
Echinococcus granulosus	sodium dependent neurotransmitter transporter	0.0098	0.0915	0.0915
Schistosoma mansoni	methyl-cpg binding protein mbd	0.0055	0.0344	0.0444
Echinococcus granulosus	GPCR family 2	0.0066	0.0498	0.0498
Loa Loa (eye worm)	hypothetical protein	0.0039	0.0131	0.0116
Loa Loa (eye worm)	norepinephrine transporter	0.0576	0.7245	0.7241
Echinococcus multilocularis	methyl CpG binding domain protein 2	0.0055	0.0344	0.0322
Echinococcus multilocularis	cpg binding protein	0.0036	0.0102	0.008
Schistosoma mansoni	hypothetical protein	0.0066	0.0498	0.0658
Loa Loa (eye worm)	hypothetical protein	0.0784	1	1
Trichomonas vaginalis	set domain proteins, putative	0.0237	0.2756	1
Trypanosoma cruzi	apurinic/apyrimidinic endonuclease	0.0058	0.0385	1
Loa Loa (eye worm)	hypothetical protein	0.0227	0.262	0.261
Schistosoma mansoni	hypothetical protein	0.0066	0.0496	0.0655
Echinococcus granulosus	dnaJ subfamily B	0.0408	0.502	0.502
Schistosoma mansoni	sodium/chloride dependent transporter	0.0576	0.7245	1
Loa Loa (eye worm)	jmjC domain-containing protein	0.0082	0.0702	0.0688
Brugia malayi	latrophilin 2 splice variant baaae	0.0143	0.1516	0.1496
Echinococcus granulosus	sodium and chloride dependent glycine	0.0098	0.0915	0.0915
Echinococcus granulosus	Aryl hydrocarbon receptor nuclear	0.008	0.068	0.068
Brugia malayi	bHLH-PAS transcription factor	0.0038	0.0119	0.0097
Brugia malayi	PHD-finger family protein	0.0081	0.0699	0.0677
Loa Loa (eye worm)	hypothetical protein	0.0143	0.1516	0.1503
Loa Loa (eye worm)	hypothetical protein	0.0576	0.7245	0.7241
Loa Loa (eye worm)	hypothetical protein	0.0138	0.1451	0.1439
Schistosoma mansoni	hypothetical protein	0.0169	0.1857	0.254
Plasmodium falciparum	amino acid transporter, putative	0.0098	0.0915	1
Schistosoma mansoni	sodium-dependent neurotransmitter transporter	0.0098	0.0915	0.1235
Echinococcus multilocularis	histone lysine methyltransferase setb histone lysine methyltransferase eggless	0.0085	0.0746	0.0725
Echinococcus multilocularis	zinc finger protein	0.0064	0.0472	0.0451
Echinococcus granulosus	jumonji domain containing protein	0.0085	0.0746	0.0746

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?

In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.

In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

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Bibliographic References

No literature references available for this target.

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Detailed information for compound 800578