Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0187 | 0.3675 | 0.3675 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0073 | 0.0843 | 0.0795 |
Loa Loa (eye worm) | PHD-finger family protein | 0.0057 | 0.045 | 0.04 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0191 | 0.0703 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0047 | 0.0191 | 0.014 |
Schistosoma mansoni | acetyl-CoA C-acetyltransferase | 0.0045 | 0.0147 | 0.0539 |
Loa Loa (eye worm) | hypothetical protein | 0.0057 | 0.045 | 0.04 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0191 | 0.0703 |
Echinococcus granulosus | jumonji domain containing protein | 0.0079 | 0.1006 | 0.1006 |
Plasmodium falciparum | phd finger protein, putative | 0.0057 | 0.045 | 0.5 |
Echinococcus multilocularis | muscleblind protein 1 | 0.0441 | 1 | 1 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0057 | 0.045 | 0.5 |
Schistosoma mansoni | jumonji domain containing protein | 0.0148 | 0.2721 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0073 | 0.0843 | 0.3098 |
Brugia malayi | Bromodomain containing protein | 0.0062 | 0.0567 | 0.0383 |
Schistosoma mansoni | bromodomain-containing nuclear protein 1 brd1 | 0.0057 | 0.045 | 0.1656 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0071 | 0.0808 | 0.0808 |
Echinococcus granulosus | muscleblind protein | 0.0441 | 1 | 1 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0118 | 0.196 | 0.1917 |
Plasmodium vivax | hypothetical protein, conserved | 0.0057 | 0.045 | 0.5 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0047 | 0.0191 | 0.0191 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0069 | 0.0749 | 0.0749 |
Echinococcus granulosus | peregrin | 0.0062 | 0.0567 | 0.0567 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0073 | 0.0843 | 0.0843 |
Schistosoma mansoni | hypothetical protein | 0.0101 | 0.1535 | 0.5642 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0047 | 0.0191 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0047 | 0.0191 | 0.014 |
Echinococcus granulosus | PHD finger protein rhinoceros | 0.0057 | 0.045 | 0.045 |
Loa Loa (eye worm) | hypothetical protein | 0.014 | 0.2526 | 0.2486 |
Echinococcus multilocularis | bromodomain adjacent to zinc finger domain | 0.0119 | 0.1981 | 0.1981 |
Brugia malayi | jmjC domain containing protein | 0.0073 | 0.0843 | 0.0664 |
Loa Loa (eye worm) | hypothetical protein | 0.0098 | 0.1463 | 0.1418 |
Loa Loa (eye worm) | hypothetical protein | 0.0081 | 0.1045 | 0.0998 |
Echinococcus multilocularis | GPCR, family 2 | 0.0047 | 0.0191 | 0.0191 |
Brugia malayi | jmjC domain containing protein | 0.0187 | 0.3675 | 0.3552 |
Loa Loa (eye worm) | hypothetical protein | 0.0101 | 0.1535 | 0.1491 |
Brugia malayi | Corticotropin releasing factor receptor 2 precursor, putative | 0.0147 | 0.2693 | 0.2551 |
Loa Loa (eye worm) | hypothetical protein | 0.0076 | 0.0928 | 0.088 |
Loa Loa (eye worm) | hypothetical protein | 0.0441 | 1 | 1 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0047 | 0.0191 | 0.0191 |
Loa Loa (eye worm) | hypothetical protein | 0.0147 | 0.2693 | 0.2655 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0187 | 0.3675 | 0.3675 |
Brugia malayi | PHD-finger family protein | 0.0057 | 0.045 | 0.0264 |
Brugia malayi | PHD-finger family protein | 0.0049 | 0.0263 | 0.0074 |
Schistosoma mansoni | hypothetical protein | 0.0057 | 0.045 | 0.1656 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0101 | 0.1535 | 0.137 |
Onchocerca volvulus | Alhambra homolog | 0.0057 | 0.045 | 0.5 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0147 | 0.2693 | 0.2551 |
Schistosoma mansoni | bromodomain containing protein | 0.0126 | 0.2158 | 0.7932 |
Echinococcus granulosus | GPCR family 2 | 0.0047 | 0.0191 | 0.0191 |
Echinococcus multilocularis | peregrin | 0.0062 | 0.0567 | 0.0567 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0191 | 0.0703 |
Schistosoma mansoni | hypothetical protein | 0.0041 | 0.0052 | 0.0192 |
Echinococcus multilocularis | fetal alzheimer antigen, falz | 0.0045 | 0.0147 | 0.0147 |
Brugia malayi | Bromodomain containing protein | 0.0149 | 0.2737 | 0.2595 |
Echinococcus multilocularis | muscleblind protein | 0.0441 | 1 | 1 |
Echinococcus granulosus | fetal alzheimer antigen falz | 0.0045 | 0.0147 | 0.0147 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0147 | 0.2693 | 0.2655 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0073 | 0.0843 | 0.3098 |
Echinococcus multilocularis | PHD finger protein rhinoceros | 0.0057 | 0.045 | 0.045 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0119 | 0.1981 | 0.1981 |
Loa Loa (eye worm) | hypothetical protein | 0.0441 | 1 | 1 |
Echinococcus granulosus | bromodomain adjacent to zinc finger domain | 0.0071 | 0.0808 | 0.0808 |
Echinococcus multilocularis | jumonji domain containing protein | 0.0079 | 0.1006 | 0.1006 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.1139 | 0.1093 |
Toxoplasma gondii | PHD-finger domain-containing protein | 0.0057 | 0.045 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0047 | 0.0191 | 0.0703 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0047 | 0.0191 | 0.0191 |
Giardia lamblia | PHD finger protein 15 | 0.0057 | 0.045 | 0.5 |
Brugia malayi | Bromodomain containing protein | 0.0076 | 0.0925 | 0.0748 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.