Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.024 | 0.0262 |
Brugia malayi | Nuclear hormone receptor family member nhr-1 | 0.003 | 0.0598 | 0.0775 |
Brugia malayi | jmjC domain containing protein | 0.0033 | 0.0657 | 0.0858 |
Brugia malayi | nuclear receptor NHR-88 | 0.003 | 0.0598 | 0.0775 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0598 | 0.0583 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0598 | 0.0775 |
Brugia malayi | Nuclear hormone receptor family member nhr-31 | 0.003 | 0.0598 | 0.0775 |
Brugia malayi | Nuclear hormone receptor family member nhr-3 | 0.003 | 0.0598 | 0.0775 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0197 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0035 | 0.073 | 0.9948 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0975 | 0.0961 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.1975 | 1 |
Echinococcus granulosus | jumonji domain containing 1A | 0.0033 | 0.0657 | 0.0642 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0733 | 0.0968 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.024 | 0.0258 |
Schistosoma mansoni | coup transcription factor | 0.003 | 0.0598 | 0.0583 |
Onchocerca volvulus | 0.0036 | 0.0733 | 1 | |
Schistosoma mansoni | phd/f-box containing protein | 0.0033 | 0.0657 | 0.0642 |
Schistosoma mansoni | hypothetical protein | 0.0404 | 1 | 1 |
Schistosoma mansoni | ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related | 0.0033 | 0.0657 | 0.0642 |
Echinococcus granulosus | nuclear receptor subfamily 4 group A | 0.0014 | 0.0197 | 0.0181 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0975 | 0.0961 |
Treponema pallidum | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.1975 | 1 |
Echinococcus multilocularis | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0598 | 0.0583 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0733 | 0.0718 |
Echinococcus granulosus | expressed protein | 0.0036 | 0.0751 | 0.0737 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.003 | 0.0598 | 0.0583 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.003 | 0.0598 | 0.0775 |
Echinococcus granulosus | lysine specific demethylase 6a | 0.0033 | 0.0657 | 0.0642 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0014 | 0.0197 | 0.0201 |
Trypanosoma cruzi | peptidyl-prolyl cis-trans isomerase | 0.0035 | 0.073 | 0.9948 |
Brugia malayi | hypothetical protein | 0.0016 | 0.024 | 0.0262 |
Plasmodium vivax | JmjC domain containing protein | 0.0033 | 0.0657 | 0.0585 |
Echinococcus multilocularis | thyroid hormone receptor alpha | 0.003 | 0.0598 | 0.0583 |
Echinococcus multilocularis | nuclear receptor subfamily 1 group D | 0.0016 | 0.024 | 0.0224 |
Brugia malayi | ecdysone receptor | 0.0014 | 0.0197 | 0.0201 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.003 | 0.0598 | 0.0583 |
Toxoplasma gondii | peptidylprolyl isomerase | 0.0035 | 0.073 | 0.3301 |
Echinococcus multilocularis | expressed protein | 0.0036 | 0.0751 | 0.0737 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0033 | 0.0657 | 0.0855 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.003 | 0.0598 | 0.0583 |
Echinococcus granulosus | FTZ F1 alpha | 0.003 | 0.0598 | 0.0583 |
Brugia malayi | orphan nuclear receptor NR2E1 | 0.0014 | 0.0197 | 0.0201 |
Echinococcus granulosus | Jumonji AT rich interactive domain 1B | 0.0034 | 0.0697 | 0.0683 |
Echinococcus multilocularis | peptidase Clp (S14 family) | 0.0056 | 0.1239 | 0.1225 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.024 | 0.0258 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0197 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0085 | 0.1975 | 1 |
Toxoplasma gondii | histone lysine demethylase JMJD6a | 0.0033 | 0.0657 | 0.2908 |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0.0598 | 0.0583 |
Echinococcus granulosus | lysine specific demethylase 5A | 0.0124 | 0.2947 | 0.2936 |
Echinococcus granulosus | thyroid hormone receptor alpha | 0.0014 | 0.0197 | 0.0181 |
Echinococcus granulosus | FTZ F1 nuclear receptor protein | 0.003 | 0.0598 | 0.0583 |
Onchocerca volvulus | Bile acid receptor homolog | 0.003 | 0.0598 | 0.7483 |
Plasmodium falciparum | JmjC domain-containing protein, putative | 0.0033 | 0.0657 | 0.0585 |
Echinococcus granulosus | cpg binding protein | 0.003 | 0.0593 | 0.0578 |
Schistosoma mansoni | jumonji domain containing protein | 0.0033 | 0.0657 | 0.0642 |
Brugia malayi | Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative | 0.0036 | 0.0733 | 0.0968 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0733 | 0.9756 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0733 | 0.0964 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0975 | 0.0961 |
Schistosoma mansoni | zinc finger protein | 0.0014 | 0.0197 | 0.0181 |
Entamoeba histolytica | peptidyl-prolyl cis-trans isomerase, putative | 0.0035 | 0.073 | 0.5 |
Brugia malayi | ecdysteroid receptor | 0.003 | 0.0598 | 0.0775 |
Echinococcus multilocularis | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.1975 | 0.1963 |
Brugia malayi | nuclear receptor RXR | 0.0016 | 0.024 | 0.0262 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-31 | 0.003 | 0.0598 | 0.0771 |
Schistosoma mansoni | peptidase Clp (S14 family) | 0.0085 | 0.1975 | 0.1963 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.003 | 0.0598 | 0.0583 |
Schistosoma mansoni | nuclear receptor | 0.0014 | 0.0197 | 0.0181 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0975 | 0.0961 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.024 | 0.0258 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.1975 | 0.5 |
Schistosoma mansoni | hepatocyte nuclear factor 4-alpha (hnf-4-alpha) | 0.0014 | 0.0197 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0598 | 0.0771 |
Echinococcus multilocularis | nuclear receptor co repressor related (ncor) | 0.0299 | 0.7368 | 0.7364 |
Loa Loa (eye worm) | hypothetical protein | 0.0287 | 0.7049 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.024 | 0.0258 |
Leishmania major | hypothetical protein, conserved | 0.0036 | 0.0733 | 1 |
Schistosoma mansoni | nuclear hormone receptor | 0.0014 | 0.0197 | 0.0181 |
Brugia malayi | nuclear receptor subfamily 1, group D, member 1, putative | 0.0014 | 0.0197 | 0.0201 |
Echinococcus multilocularis | jumonji domain containing 1A | 0.0033 | 0.0657 | 0.0642 |
Trypanosoma brucei | JmjC domain, hydroxylase, putative | 0.0033 | 0.0657 | 0.8764 |
Echinococcus granulosus | retinoic acid receptor rxr beta a | 0.003 | 0.0598 | 0.0583 |
Brugia malayi | tailless protein | 0.0014 | 0.0197 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0733 | 0.0964 |
Brugia malayi | nuclear receptor RXR | 0.0014 | 0.0197 | 0.0201 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.0016 | 0.024 | 0.0224 |
Echinococcus multilocularis | retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha | 0.0014 | 0.0197 | 0.0181 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0733 | 0.9756 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-41 | 0.003 | 0.0598 | 0.0771 |
Brugia malayi | steroid hormone receptor | 0.003 | 0.0598 | 0.0775 |
Brugia malayi | nuclear hormone receptor family member nhr-6 | 0.0014 | 0.0197 | 0.0201 |
Echinococcus multilocularis | lysine specific demethylase 6a | 0.0033 | 0.0657 | 0.0642 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0033 | 0.0657 | 0.0855 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.0014 | 0.0197 | 0.0181 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.003 | 0.0598 | 0.0583 |
Schistosoma mansoni | jumonji domain containing protein | 0.0122 | 0.2907 | 0.2896 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0197 |
Loa Loa (eye worm) | nuclear receptor nhr-7B | 0.0014 | 0.0197 | 0.0197 |
Echinococcus multilocularis | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0598 | 0.0583 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-14 | 0.003 | 0.0598 | 0.0771 |
Trichomonas vaginalis | conserved hypothetical protein | 0.0036 | 0.0751 | 1 |
Echinococcus granulosus | phd:f box containing protein | 0.0033 | 0.0657 | 0.0642 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0593 | 0.0578 |
Toxoplasma gondii | hypothetical protein | 0.0029 | 0.0575 | 0.2467 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0598 | 0.0775 |
Echinococcus granulosus | COUP TF:Svp nuclear hormone receptor | 0.003 | 0.0598 | 0.0583 |
Brugia malayi | Nuclear hormone receptor-like 1 | 0.0016 | 0.024 | 0.0262 |
Echinococcus granulosus | hepatocyte nuclear factor 4 alpha | 0.003 | 0.0598 | 0.0583 |
Plasmodium falciparum | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.1975 | 1 |
Echinococcus multilocularis | nuclear receptor subfamily 4 group A | 0.0014 | 0.0197 | 0.0181 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0197 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0197 |
Loa Loa (eye worm) | Pin1-type peptidyl-prolyl cis-trans isomerase | 0.0036 | 0.0751 | 0.099 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0045 | 0.0975 | 0.131 |
Onchocerca volvulus | Protein ultraspiracle homolog | 0.003 | 0.0598 | 0.7483 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0014 | 0.0197 | 0.0181 |
Echinococcus multilocularis | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0598 | 0.0583 |
Brugia malayi | Probable ClpP-like protease | 0.0085 | 0.1975 | 0.2745 |
Trichomonas vaginalis | rotamase, putative | 0.0036 | 0.0751 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor-like 1 | 0.0016 | 0.024 | 0.0258 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-49 | 0.003 | 0.0598 | 0.0771 |
Echinococcus granulosus | nuclear receptor 2DBD gamma | 0.0014 | 0.0197 | 0.0181 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0657 | 0.0855 |
Brugia malayi | jmjC domain containing protein | 0.0033 | 0.0657 | 0.0858 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0014 | 0.0197 | 0.0181 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0598 | 0.0583 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0598 | 0.0775 |
Toxoplasma gondii | ATP-dependent Clp endopeptidase, proteolytic subunit ClpP domain-containing protein | 0.0085 | 0.1975 | 1 |
Schistosoma mansoni | cpg binding protein | 0.003 | 0.0593 | 0.0578 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0733 | 0.9756 |
Trichomonas vaginalis | esterase, putative | 0.0036 | 0.0733 | 0.9756 |
Brugia malayi | jmjC domain containing protein | 0.0122 | 0.2907 | 0.4076 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0733 | 0.0964 |
Brugia malayi | Nuclear hormone receptor family member nhr-49 | 0.003 | 0.0598 | 0.0775 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0197 |
Echinococcus multilocularis | Nuclear hormone receptor HR96 | 0.0014 | 0.0197 | 0.0181 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.003 | 0.0598 | 0.0583 |
Echinococcus granulosus | ecdysone induced protein 78C | 0.003 | 0.0598 | 0.0583 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0045 | 0.0975 | 0.1313 |
Schistosoma mansoni | phosphatidylserine receptor | 0.0033 | 0.0657 | 0.0642 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0598 | 0.0771 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0036 | 0.0733 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0598 | 0.0771 |
Brugia malayi | nuclear receptor NHR-67 | 0.0014 | 0.0197 | 0.0201 |
Echinococcus multilocularis | JmjC domain containing protein 4 | 0.0033 | 0.0657 | 0.0642 |
Brugia malayi | Protein kinase domain containing protein | 0.0278 | 0.6827 | 0.9682 |
Brugia malayi | Nuclear hormone receptor family member nhr-14 | 0.003 | 0.0598 | 0.0775 |
Loa Loa (eye worm) | nuclear hormone receptor | 0.0014 | 0.0197 | 0.0197 |
Loa Loa (eye worm) | beta-LACTamase domain containing family member | 0.0036 | 0.0733 | 0.0964 |
Schistosoma mansoni | cpg binding protein | 0.0028 | 0.0552 | 0.0537 |
Echinococcus multilocularis | nuclear receptor nhr 48 | 0.0014 | 0.0197 | 0.0181 |
Chlamydia trachomatis | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.1975 | 0.5 |
Echinococcus multilocularis | cpg binding protein | 0.003 | 0.0593 | 0.0578 |
Schistosoma mansoni | nuclear hormone receptor | 0.003 | 0.0598 | 0.0583 |
Brugia malayi | beta-lactamase family protein | 0.0036 | 0.0733 | 0.0968 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0059 | 0.0044 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0045 | 0.0975 | 0.0961 |
Brugia malayi | hypothetical protein | 0.0016 | 0.024 | 0.0262 |
Brugia malayi | nuclear hormone receptor family member odr-7 | 0.0014 | 0.0197 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0598 | 0.0771 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0598 | 0.0771 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0009 | 0.0059 | 0.0044 |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.003 | 0.0598 | 0.0583 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0033 | 0.0657 | 0.8764 |
Echinococcus multilocularis | ecdysone induced protein 78C | 0.003 | 0.0598 | 0.0583 |
Echinococcus granulosus | nuclear receptor nhr 48 | 0.0014 | 0.0197 | 0.0181 |
Onchocerca volvulus | 0.0036 | 0.0733 | 1 | |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0197 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0197 |
Echinococcus multilocularis | Transcription factor, JmjC domain containing protein | 0.0122 | 0.2907 | 0.2896 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0197 |
Loa Loa (eye worm) | steroid hormone receptor | 0.003 | 0.0598 | 0.0771 |
Schistosoma mansoni | nuclear receptor nhr-48 | 0.0014 | 0.0197 | 0.0181 |
Brugia malayi | jmjC domain containing protein | 0.0124 | 0.2947 | 0.4134 |
Leishmania major | peptidyl-prolyl cis-trans isomerase/rotamase, putative,PPIase, putative | 0.0035 | 0.073 | 0.9948 |
Echinococcus multilocularis | Jumonji, AT rich interactive domain 1B | 0.0034 | 0.0697 | 0.0683 |
Schistosoma mansoni | nuclear receptor | 0.0014 | 0.0197 | 0.0181 |
Trypanosoma cruzi | JmjC domain, hydroxylase, putative | 0.0033 | 0.0657 | 0.8764 |
Echinococcus multilocularis | beta LACTamase domain containing family member | 0.0036 | 0.0733 | 0.0718 |
Mycobacterium leprae | Probable lipase LipE | 0.0036 | 0.0733 | 0.1129 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0598 | 0.0771 |
Schistosoma mansoni | thyroid hormone receptor | 0.003 | 0.0598 | 0.0583 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.003 | 0.0598 | 0.0583 |
Brugia malayi | Nuclear hormone receptor family member nhr-19 | 0.003 | 0.0598 | 0.0775 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0404 | 1 | 1 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0028 | 0.0552 | 0.0705 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0054 | 0.119 | 0.5777 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0033 | 0.0657 | 0.0855 |
Brugia malayi | Pin1-type peptidyl-prolyl cis-trans isomerase, BmPin1 | 0.0036 | 0.0751 | 0.0994 |
Schistosoma mansoni | family S12 unassigned peptidase (S12 family) | 0.0036 | 0.0733 | 0.0718 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0657 | 0.0855 |
Trichomonas vaginalis | rotamase, putative | 0.0035 | 0.073 | 0.9714 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0197 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 1 ClpP1 (endopeptidase CLP) | 0.0056 | 0.1239 | 0.105 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0733 | 0.0964 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.003 | 0.0598 | 0.0583 |
Trichomonas vaginalis | penicillin-binding protein, putative | 0.0036 | 0.0733 | 0.9756 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0197 |
Loa Loa (eye worm) | nuclear Hormone Receptor family member | 0.003 | 0.0598 | 0.0771 |
Echinococcus multilocularis | nuclear receptor 2DBD gamma | 0.003 | 0.0598 | 0.0583 |
Wolbachia endosymbiont of Brugia malayi | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.1975 | 1 |
Echinococcus multilocularis | phd:f box containing protein | 0.0033 | 0.0657 | 0.0642 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0598 | 0.0771 |
Toxoplasma gondii | histone lysine demethylase JMJC1/KDM5D/JARID1D | 0.0033 | 0.0657 | 0.2908 |
Mycobacterium ulcerans | ATP-dependent Clp protease proteolytic subunit | 0.0085 | 0.1975 | 1 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-40 | 0.003 | 0.0598 | 0.0771 |
Brugia malayi | Ligand-binding domain of nuclear hormone receptor family protein | 0.003 | 0.0598 | 0.0775 |
Loa Loa (eye worm) | nuclear receptor NHR-67 | 0.0014 | 0.0197 | 0.0197 |
Loa Loa (eye worm) | TK/FAK protein kinase | 0.0278 | 0.6827 | 0.9682 |
Echinococcus multilocularis | protein tyrosine kinase | 0.0275 | 0.6745 | 0.674 |
Echinococcus granulosus | Nuclear hormone receptor family member nhr 41 | 0.003 | 0.0598 | 0.0583 |
Brugia malayi | Nuclear hormone receptor family member nhr-41 | 0.003 | 0.0598 | 0.0775 |
Leishmania major | hypothetical protein, conserved | 0.0033 | 0.0657 | 0.8764 |
Plasmodium vivax | hypothetical protein, conserved | 0.0036 | 0.0733 | 0.1129 |
Brugia malayi | conserved hypotetical protein | 0.0014 | 0.0197 | 0.0201 |
Brugia malayi | Steroid receptor seven-up type 2 | 0.003 | 0.0598 | 0.0775 |
Brugia malayi | jmjC domain containing protein | 0.0033 | 0.0657 | 0.0858 |
Echinococcus granulosus | Transcription factor JmjC domain containing protein | 0.0122 | 0.2907 | 0.2896 |
Trypanosoma brucei | peptidyl-prolyl cis-trans isomerase/rotamase, putative | 0.0035 | 0.073 | 0.9948 |
Brugia malayi | nuclear hormone receptor | 0.0014 | 0.0197 | 0.0201 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0733 | 0.0964 |
Schistosoma mansoni | tyrosine kinase | 0.0275 | 0.6745 | 0.674 |
Brugia malayi | Nuclear hormone receptor family member nhr-40 | 0.003 | 0.0598 | 0.0775 |
Echinococcus multilocularis | FTZ F1 alpha | 0.003 | 0.0598 | 0.0583 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0197 |
Mycobacterium leprae | conserved hypothetical protein | 0.0036 | 0.0733 | 0.1129 |
Loa Loa (eye worm) | DR-78 | 0.0014 | 0.0197 | 0.0197 |
Toxoplasma gondii | ABC1 family protein | 0.0036 | 0.0733 | 0.3318 |
Echinococcus granulosus | Nuclear hormone receptor HR96 | 0.0014 | 0.0197 | 0.0181 |
Brugia malayi | Nuclear hormone receptor E75 | 0.0014 | 0.0197 | 0.0201 |
Echinococcus multilocularis | lysine specific demethylase 5A | 0.0122 | 0.2907 | 0.2896 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.006 | 0.1352 | 0.1338 |
Schistosoma mansoni | nuclear hormone receptor | 0.0014 | 0.0197 | 0.0181 |
Onchocerca volvulus | 0.0036 | 0.0733 | 1 | |
Brugia malayi | nuclear hormone receptor | 0.003 | 0.0598 | 0.0775 |
Echinococcus granulosus | JmjC domain containing protein 4 | 0.0033 | 0.0657 | 0.0642 |
Brugia malayi | hypothetical protein | 0.0014 | 0.0197 | 0.0201 |
Onchocerca volvulus | Steroid hormone receptor family member cnr14 homolog | 0.003 | 0.0598 | 0.7483 |
Loa Loa (eye worm) | hypothetical protein | 0.0016 | 0.024 | 0.0258 |
Loa Loa (eye worm) | beta-lactamase | 0.0036 | 0.0733 | 0.0964 |
Echinococcus granulosus | ATP dependent Clp protease proteolytic subunit | 0.0085 | 0.1975 | 0.1963 |
Plasmodium vivax | ATP-dependent Clp protease proteolytic subunit, putative | 0.0085 | 0.1975 | 1 |
Echinococcus multilocularis | FTZ F1 nuclear receptor protein | 0.003 | 0.0598 | 0.0583 |
Onchocerca volvulus | 0.003 | 0.0598 | 0.7483 | |
Schistosoma mansoni | ecdysone-induced protein 78c (dr-78) | 0.0016 | 0.024 | 0.0224 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0287 | 0.7049 | 1 |
Schistosoma mansoni | protein phosphatase 2C | 0.0033 | 0.0657 | 0.0642 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0045 | 0.0975 | 0.0961 |
Echinococcus granulosus | peptidase Clp S14 family | 0.0056 | 0.1239 | 0.1225 |
Echinococcus granulosus | protein tyrosine kinase | 0.0275 | 0.6745 | 0.674 |
Echinococcus granulosus | nuclear receptor co repressor related ncor | 0.0299 | 0.7368 | 0.7364 |
Loa Loa (eye worm) | hypothetical protein | 0.0085 | 0.1975 | 0.2742 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0733 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0197 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0036 | 0.0733 | 1 |
Schistosoma mansoni | rotamase | 0.0036 | 0.0751 | 0.0737 |
Loa Loa (eye worm) | hypothetical protein | 0.0033 | 0.0657 | 0.0855 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0124 | 0.2947 | 0.2936 |
Mycobacterium tuberculosis | Possible penicillin-binding protein | 0.0227 | 0.5553 | 1 |
Schistosoma mansoni | jumonji/arid domain-containing protein | 0.0124 | 0.2947 | 0.2936 |
Brugia malayi | Nuclear hormone receptor family member nhr-25 | 0.003 | 0.0598 | 0.0775 |
Trichomonas vaginalis | D-aminoacylase, putative | 0.0036 | 0.0733 | 0.9756 |
Schistosoma mansoni | nuclear hormone receptor superfamily protein-related | 0.0014 | 0.0197 | 0.0181 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 CLPP1 (ENDOPEPTIDASE CLP) | 0.0056 | 0.1239 | 0.4744 |
Mycobacterium leprae | PROBABLE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 CLPP2 (ENDOPEPTIDASE CLP 2) | 0.0085 | 0.1975 | 1 |
Brugia malayi | jmjC domain containing protein | 0.0033 | 0.0657 | 0.0858 |
Loa Loa (eye worm) | hypothetical protein | 0.0014 | 0.0197 | 0.0197 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0045 | 0.0975 | 0.0961 |
Brugia malayi | beta-lactamase | 0.0036 | 0.0733 | 0.0968 |
Echinococcus granulosus | beta LACTamase domain containing family member | 0.0036 | 0.0733 | 0.0718 |
Brugia malayi | CXXC zinc finger family protein | 0.0028 | 0.0552 | 0.0709 |
Loa Loa (eye worm) | hypothetical protein | 0.0036 | 0.0733 | 0.0964 |
Mycobacterium tuberculosis | Probable ATP-dependent CLP protease proteolytic subunit 2 ClpP2 (endopeptidase CLP 2) | 0.0056 | 0.1239 | 0.105 |
Loa Loa (eye worm) | nuclear hormone receptor family member nhr-1 | 0.003 | 0.0598 | 0.0771 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.003 | 0.0598 | 0.0583 |
Brugia malayi | nuclear receptor NHR-88 | 0.0014 | 0.0197 | 0.0201 |
Onchocerca volvulus | 0.0028 | 0.0552 | 0.6625 | |
Echinococcus granulosus | nuclear receptor subfamily 1 group D | 0.0016 | 0.024 | 0.0224 |
Loa Loa (eye worm) | jmjC domain-containing protein | 0.0124 | 0.2947 | 0.4132 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.