Detailed information for compound 801108

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 471.543 | Formula: C26H33NO7
  • H donors: 1 H acceptors: 3 LogP: 3.44 Rotable bonds: 11
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCCOc1ccc(cc1)C1C(=C(C)N=C2C1=C(O)C(C(C2)C)C(=O)OC)C(=O)OCCOC
  • InChi: 1S/C26H33NO7/c1-6-11-33-18-9-7-17(8-10-18)22-21(26(30)34-13-12-31-4)16(3)27-19-14-15(2)20(25(29)32-5)24(28)23(19)22/h7-10,15,20,22,28H,6,11-14H2,1-5H3
  • InChiKey: FHEHXAQRRRSZEV-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.012 0.012
Echinococcus multilocularis pyruvate kinase 0.0069 0.0206 0.0206
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0494 0.0494
Brugia malayi photoreceptor-specific nuclear receptor 0.0021 0.0017 0.0048
Entamoeba histolytica pyruvate kinase, putative 0.0048 0.0124 0.0873
Plasmodium vivax glutathione reductase, putative 0.0051 0.0137 0.0387
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0682 0.5008
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0244 0.069
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0196 0.0555
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0006 0.0006
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0494 0.0494
Mycobacterium ulcerans dihydroorotate dehydrogenase 2 0.0905 0.3533 1
Echinococcus multilocularis chromobox protein 1 0.0075 0.0233 0.0233
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0001 0.0001
Echinococcus granulosus neuropeptide receptor 0.0047 0.012 0.012
Onchocerca volvulus Protein ultraspiracle homolog 0.0021 0.0017 0.0098
Leishmania major cathepsin L-like protease 0.0018 0.0006 0.0012
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.012 0.012
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0047 0.012 0.012
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0006 0.0006
Brugia malayi Pre-SET motif family protein 0.0034 0.007 0.0199
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0014 0.0075
Brugia malayi steroid hormone receptor 0.0021 0.0017 0.0048
Echinococcus multilocularis ecdysone induced protein 78C 0.0021 0.0017 0.0017
Trypanosoma cruzi hexokinase, putative 0.0078 0.0242 0.0686
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0006 0.0011
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0028 0.0044 0.0125
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0047 0.012 0.012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0059 0.0168 0.1215
Echinococcus granulosus Regulator of G protein signaling 20 0.0021 0.0016 0.0016
Onchocerca volvulus 0.0071 0.0218 0.1265
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0014 0.0014
Brugia malayi hypothetical protein 0.0047 0.012 0.0341
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0016 0.0016
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0105 0.0351 0.0994
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0078 0.0244 0.105
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.002 0.0014 0.0014
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0141 0.0494 0.0494
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0081 0.0256 0.0724
Onchocerca volvulus 0.0033 0.0065 0.0379
Toxoplasma gondii aldehyde dehydrogenase 0.0066 0.0195 0.0551
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0018 0.0004 0.0007
Echinococcus granulosus microtubule associated protein 2 0.1385 0.5444 0.5444
Echinococcus multilocularis pyruvate kinase 0.0054 0.0149 0.0149
Brugia malayi Calcitonin receptor-like protein seb-1 0.0447 0.1712 0.4845
Trypanosoma cruzi small ubiquitin protein, putative 0.0051 0.0136 0.0384
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0026 0.0037 0.0037
Toxoplasma gondii hexokinase 0.0078 0.0242 0.0686
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0358 0.1358 1
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0016 0.0016
Echinococcus granulosus lamin 0.0054 0.0149 0.0149
Trypanosoma brucei chrX additional, unordered contigs 0.0036 0.0077 0.0218
Plasmodium vivax ataxin-2 like protein, putative 0.0101 0.0337 0.0954
Echinococcus multilocularis pyruvate kinase 0.0069 0.0206 0.0206
Loa Loa (eye worm) mbt repeat family protein 0.0048 0.0124 0.0534
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0065 0.0192 0.0192
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0047 0.012 0.0519
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0018 0.0006 0.0016
Schistosoma mansoni eyes absent homolog 0.0088 0.0284 0.0284
Leishmania major trypanothione reductase 0.0051 0.0137 0.0384
Giardia lamblia DINP protein human, muc B family 0.0123 0.0423 0.618
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0088
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.012 0.012
Plasmodium vivax DNA repair protein REV1, putative 0.0036 0.0077 0.0218
Echinococcus multilocularis glutamate receptor 2 0.0028 0.0047 0.0047
Plasmodium vivax SET domain protein, putative 0.0034 0.007 0.0199
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0017 0.0001 0.0004
Loa Loa (eye worm) hypothetical protein 0.0198 0.0723 0.3113
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0074 0.0229 0.0229
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0016 0.0016
Trichomonas vaginalis bromodomain-containing protein, putative 0.0042 0.0099 0.0701
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0047 0.012 0.0519
Brugia malayi Pip kinase protein 1 0.0028 0.0044 0.0125
Schistosoma mansoni hypothetical protein 0.0047 0.012 0.012
Trypanosoma cruzi DNA polymerase eta, putative 0.0061 0.0176 0.0497
Schistosoma mansoni steroid hormone receptor ad4bp 0.0021 0.0017 0.0017
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0021 0.0017 0.0017
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0105 0.0351 0.0351
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0021 0.0017 0.0073
Schistosoma mansoni opsin-like receptor 0.0047 0.012 0.012
Echinococcus multilocularis RUN 0.0021 0.0018 0.0018
Brugia malayi Glutamate receptor 2 precursor 0.0033 0.0065 0.0183
Schistosoma mansoni biogenic amine (5HT) receptor 0.0047 0.012 0.012
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0047 0.012 0.012
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0021 0.0017 0.0017
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0021 0.0017 0.0073
Trypanosoma brucei DNA polymerase kappa, putative 0.0123 0.0423 0.1197
Onchocerca volvulus 0.0078 0.0244 0.1417
Brugia malayi hypothetical protein 0.0021 0.0016 0.0045
Onchocerca volvulus 0.0021 0.0017 0.0098
Schistosoma mansoni intermediate filament proteins 0.0054 0.0149 0.0149
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0014 0.0014
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0123 0.0423 0.1194
Echinococcus granulosus somatostatin receptor 0.0047 0.012 0.012
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0188 0.0532
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0119 0.0853
Loa Loa (eye worm) hypothetical protein 0.0025 0.0032 0.0137
Onchocerca volvulus 0.0021 0.0018 0.0107
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0021 0.0017 0.0048
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0358 0.1358 0.1358
Trypanosoma brucei DNA polymerase IV, putative 0.0137 0.0479 0.1356
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0073
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type I 0.0028 0.0044 0.0044
Onchocerca volvulus 0.0047 0.012 0.07
Echinococcus granulosus hexokinase type 2 0.0078 0.0242 0.0242
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0218 0.1577
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0081 0.0256 0.0724
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Schistosoma mansoni hypothetical protein 0.0047 0.012 0.012
Echinococcus granulosus hyperpolarization activated cyclic 0.002 0.0014 0.0014
Onchocerca volvulus Huntingtin homolog 0.0122 0.042 0.2444
Onchocerca volvulus 0.0047 0.012 0.07
Trichomonas vaginalis helicase, putative 0.0047 0.0119 0.0853
Brugia malayi metabotropic glutamate receptor type 2 0.0028 0.0046 0.013
Loa Loa (eye worm) hypothetical protein 0.0042 0.0101 0.0437
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0018 0.0004 0.0011
Trypanosoma brucei DNA polymerase eta, putative 0.0141 0.0494 0.1399
Mycobacterium tuberculosis Conserved protein 0.0071 0.0218 0.0612
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0494 0.0494
Onchocerca volvulus 0.0047 0.012 0.07
Echinococcus multilocularis hexokinase 0.0078 0.0242 0.0242
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.012 0.012
Brugia malayi Doublecortin family protein 0.0021 0.0018 0.0052
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0244 0.069
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0123 0.0423 0.1194
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0021 0.0017 0.0017
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0244 0.0686
Onchocerca volvulus 0.0018 0.0006 0.0032
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0047 0.012 0.012
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0059 0.0168 0.1215
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0084 0.0269 0.0761
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Echinococcus multilocularis NMDA receptor 0.0048 0.0125 0.0125
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0218 0.0218
Plasmodium vivax multidomain scavenger receptor, putative 0.0021 0.0018 0.0052
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0021 0.0017 0.0017
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0016 0.0016
Giardia lamblia Histone acetyltransferase GCN5 0.0038 0.0085 0.1196
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0077 0.0218
Loa Loa (eye worm) hypothetical protein 0.0198 0.0723 0.3113
Brugia malayi Glutamate receptor 1 precursor 0.0033 0.0065 0.0183
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0077 0.0239 0.0239
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.002 0.0014 0.004
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0265 0.099 0.2793
Loa Loa (eye worm) hypothetical protein 0.0071 0.0218 0.0937
Schistosoma mansoni regulator of G protein signaling 0.0029 0.005 0.005
Echinococcus granulosus suppression of tumorigenicity 18 protein 0.0054 0.015 0.015
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0065 0.0192 0.0192
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0119 0.0853
Trypanosoma cruzi DNA damage repair protein, putative 0.0036 0.0077 0.0218
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0014 0.004
Echinococcus granulosus expressed protein 0.0403 0.1538 0.1538
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0337 0.0954
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0077 0.0218
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0021 0.0017 0.0048
Schistosoma mansoni nuclear hormone receptor 0.0021 0.0017 0.0017
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0018 0.0004 0.0011
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.012 0.012
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.013 0.0449 0.1267
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0439 0.1678 0.1678
Echinococcus granulosus neuropeptides capa receptor 0.0047 0.012 0.012
Schistosoma mansoni hypothetical protein 0.0306 0.1149 0.1149
Onchocerca volvulus 0.0047 0.012 0.07
Loa Loa (eye worm) doublecortin family protein 0.0021 0.0018 0.0079
Echinococcus multilocularis regulator of G protein signaling 7 0.0029 0.005 0.005
Schistosoma mansoni inositol monophosphatase 0.0081 0.0256 0.0256
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0506 0.1434
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0077 0.0239 0.0239
Onchocerca volvulus 0.0018 0.0006 0.0032
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0081 0.0256 0.186
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0218 0.1577
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.002 0.0014 0.004
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0682 0.5008
Loa Loa (eye worm) hexokinase 0.0024 0.0029 0.0126
Toxoplasma gondii small ubiquitin family modifier, putative 0.0051 0.0136 0.0384
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0021 0.0017 0.0017
Loa Loa (eye worm) pyruvate kinase 0.0069 0.0206 0.0888
Schistosoma mansoni hypothetical protein 0.1035 0.4049 0.4049
Leishmania major cysteine peptidase A (CPA) 0.0018 0.0006 0.0012
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.007 0.007
Entamoeba histolytica hypothetical protein 0.0021 0.0016 0.0077
Echinococcus granulosus chromobox protein 1 0.0075 0.0233 0.0233
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0036 0.0077 0.0218
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0047 0.012 0.07
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0052 0.0358
Entamoeba histolytica acyl-CoA synthetase, putative 0.0265 0.099 0.7278
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0193 0.07 0.07
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0014 0.0014
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0047 0.012 0.012
Onchocerca volvulus 0.0047 0.012 0.07
Echinococcus multilocularis neuropeptide s receptor 0.0047 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0029 0.005 0.0217
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0208 0.0588
Echinococcus multilocularis pyruvate kinase 0.0035 0.0073 0.0073
Leishmania major DNA damage repair protein, putative 0.0036 0.0077 0.0214
Schistosoma mansoni hypothetical protein 0.0141 0.0496 0.0496
Echinococcus granulosus g protein coupled receptor 0.0047 0.012 0.012
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.0188 0.0682 0.1927
Brugia malayi Receptor family ligand binding region containing protein 0.0019 0.0009 0.0026
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0081 0.0256 0.186
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Schistosoma mansoni smad 0.0025 0.0031 0.0031
Trypanosoma brucei mitochondrial DNA polymerase beta 0.0599 0.2318 0.6561
Echinococcus multilocularis histone acetyltransferase MYST2 0.0054 0.015 0.015
Trypanosoma cruzi phosphatidylinositol (3,5) kinase, putative 0.0028 0.0044 0.0125
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0018 0.0004 0.0011
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0016 0.0016
Toxoplasma gondii cathepsin CPL 0.0018 0.0006 0.0016
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0047 0.012 0.012
Echinococcus multilocularis serotonin receptor 0.0047 0.012 0.012
Echinococcus multilocularis fmrfamide receptor 0.0047 0.012 0.012
Echinococcus granulosus sex peptide receptor 0.0047 0.012 0.012
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0034 0.007 0.007
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0682 0.5008
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0144
Plasmodium falciparum phosphatidylinositol-4-phosphate 5-kinase 0.0028 0.0044 0.0125
Schistosoma mansoni glutamate receptor NMDA 0.0089 0.0286 0.0286
Schistosoma mansoni rab6-interacting 0.0021 0.0018 0.0018
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0047 0.012 0.012
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0078 0.0244 0.069
Echinococcus granulosus RUN 0.0021 0.0018 0.0018
Mycobacterium ulcerans hypothetical protein 0.0265 0.099 0.2793
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0018 0.0004 0.0004
Leishmania major 4-coumarate:coa ligase-like protein 0.0265 0.099 0.2798
Brugia malayi Pre-SET motif family protein 0.0212 0.0778 0.2204
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0021 0.0017 0.0073
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0081 0.0256 0.0724
Schistosoma mansoni glutamate receptor kainate 0.0033 0.0065 0.0065
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0078 0.0244 0.069
Trypanosoma brucei hexokinase 0.0078 0.0242 0.0686
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0295 0.1106 0.1106
Loa Loa (eye worm) voltage-gated potassium channel 0.052 0.2002 0.8627
Echinococcus granulosus regulator of G protein signaling 7 0.0029 0.005 0.005
Brugia malayi Dopamine receptor protein 1 0.0047 0.012 0.0341
Giardia lamblia Hypothetical protein 0.0028 0.0044 0.0591
Leishmania major cathepsin L-like protease 0.0018 0.0006 0.0012
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.012 0.012
Brugia malayi ORL1-like opioid receptor 0.0047 0.012 0.0341
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0017 0.0048
Onchocerca volvulus 0.0047 0.012 0.07
Trypanosoma cruzi DNA polymerase kappa, putative 0.0144 0.0506 0.1434
Onchocerca volvulus Rap guanine nucleotide exchange factor 1 homolog 0.0176 0.0634 0.3684
Leishmania major DNA polymerase eta, putative 0.0141 0.0494 0.1395
Loa Loa (eye worm) RGS-3 protein 0.0021 0.0016 0.0069
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0011
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0017 0.0001 0.0001
Schistosoma mansoni biogenic amine (5HT) receptor 0.0047 0.012 0.012
Loa Loa (eye worm) cysteine protease 0.0018 0.0006 0.0024
Mycobacterium ulcerans DNA polymerase IV 0.0144 0.0506 0.1424
Brugia malayi metabotropic glutamate receptor subtype 5a (mGluR5a), putative 0.0036 0.0078 0.0222
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0077 0.0218
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.002 0.0014 0.004
Schistosoma mansoni biogenic amine receptor 0.0047 0.012 0.012
Echinococcus multilocularis metabotropic glutamate receptor 2 0.0042 0.0102 0.0102
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.002 0.0014 0.0014
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0018 0.0004 0.0011
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0124 0.0124
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.028 0.0792
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Echinococcus multilocularis voltage gated potassium channel 0.002 0.0014 0.0014
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0018 0.0006 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0208 0.0588
Loa Loa (eye worm) pyruvate kinase 0.0069 0.0206 0.0888
Trichomonas vaginalis DNA helicase recq, putative 0.0023 0.0026 0.0161
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0506 0.1434
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0071 0.0218 0.0612
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0028 0.0044 0.0125
Entamoeba histolytica phosphoinositide kinase, putative 0.0028 0.0044 0.0285
Echinococcus granulosus 7TM GPCR rhodopsin 0.0047 0.012 0.012
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0021 0.0017 0.0017
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0116 0.0395 0.1703
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0021 0.0017 0.0098
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0016 0.0016
Echinococcus granulosus glutamate receptor 2 0.0045 0.0114 0.0114
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.002 0.0014 0.0075
Trichomonas vaginalis ubiquitin, putative 0.0031 0.0058 0.0402
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.012 0.012
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0141 0.0496 0.0496
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0141 0.0494 0.1398
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0078 0.0244 0.0686
Mycobacterium tuberculosis Conserved protein 0.0071 0.0218 0.0612
Schistosoma mansoni lozenge 0.0056 0.0158 0.0158
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0218 0.1577
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0028 0.0044 0.0125
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0073
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0004 0.0011
Onchocerca volvulus Pyruvate kinase homolog 0.0069 0.0206 0.1198
Onchocerca volvulus 0.0071 0.0218 0.1265
Echinococcus multilocularis nmda type glutamate receptor 0.0036 0.0077 0.0077
Onchocerca volvulus 0.0054 0.0149 0.0865
Onchocerca volvulus Polycomb protein Sfmbt homolog 0.0048 0.0124 0.0721
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0101 0.072
Treponema pallidum hexokinase (hxk) 0.0078 0.0242 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.012 0.012
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0066 0.0196 0.0844
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0116 0.0395 0.0395
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0119 0.0853
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0071 0.0218 0.0616
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0024 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0198 0.0723 0.3113
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0265 0.099 0.2793
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0047 0.012 0.012
Onchocerca volvulus 0.0047 0.012 0.07
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0021 0.0017 0.0048
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.0066 0.0195 0.0195
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0358 0.1358 1
Leishmania major cathepsin L-like protease 0.0069 0.0208 0.0585
Brugia malayi Smad1 0.0025 0.0031 0.0089
Mycobacterium ulcerans pyruvate kinase 0.0069 0.0206 0.0573
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0047 0.012 0.012
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0021 0.0018 0.0079
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0244 0.0679
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0006 0.0011
Echinococcus multilocularis sex peptide receptor 0.0047 0.012 0.012
Echinococcus granulosus histone lysine methyltransferase setb 0.0034 0.007 0.007
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0021 0.0017 0.0017
Echinococcus multilocularis hyperpolarization activated cyclic 0.002 0.0014 0.0014
Schistosoma mansoni lamin 0.0054 0.0149 0.0149
Trichomonas vaginalis DNA polymerase eta, putative 0.0144 0.0506 0.3712
Schistosoma mansoni biogenic amine receptor 0.0047 0.012 0.012
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0078 0.0244 0.1761
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.012 0.012
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0117 0.0397 0.1121
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0244 0.069
Loa Loa (eye worm) hypothetical protein 0.0058 0.0165 0.0711
Schistosoma mansoni DNA polymerase IV / kappa 0.0036 0.0077 0.0077
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0018 0.0004 0.0011
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0006 0.0032
Onchocerca volvulus 0.0047 0.012 0.07
Leishmania major hypothetical protein, conserved 0.0101 0.0337 0.0951
Plasmodium vivax pyruvate kinase, putative 0.0069 0.0206 0.0583
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0506 0.1434
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0014 0.0014
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0047 0.012 0.0519
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0018 0.0018
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.002 0.0014 0.0014
Onchocerca volvulus 0.0071 0.0218 0.1265
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0078 0.0244 0.0679
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.002 0.0014 0.0061
Brugia malayi PXA domain containing protein 0.0021 0.0016 0.0045
Brugia malayi neuropeptide F receptor 0.0047 0.012 0.0341
Trichomonas vaginalis pyruvate kinase, putative 0.0069 0.0206 0.1493
Trichomonas vaginalis antibiotic synthetase, putative 0.0078 0.0244 0.177
Echinococcus multilocularis FTZ F1 alpha 0.0021 0.0017 0.0017
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0011
Schistosoma mansoni microtubule-associated protein tau 0.1385 0.5444 0.5444
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0028 0.0044 0.0125
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0047 0.012 0.0341
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0014 0.0014
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0042 0.0099 0.028
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0016 0.0045
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0006 0.0011
Toxoplasma gondii pyruvate kinase PyKII 0.0035 0.0073 0.0208
Loa Loa (eye worm) hypothetical protein 0.0025 0.0032 0.0137
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Brugia malayi Steroid receptor seven-up type 2 0.0021 0.0017 0.0048
Schistosoma mansoni pyruvate kinase 0.0069 0.0206 0.0206
Giardia lamblia Pyruvate kinase 0.0035 0.0073 0.1024
Brugia malayi chromobox protein homolog 3 0.0042 0.0101 0.0287
Onchocerca volvulus 0.0049 0.0127 0.0741
Loa Loa (eye worm) MH2 domain-containing protein 0.0361 0.1368 0.5894
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.012 0.012
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0218 0.0616
Treponema pallidum amino acid ABC transporter, periplasmic binding protein 0.0019 0.001 0.0249
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0011
Loa Loa (eye worm) hexokinase 0.0049 0.0127 0.0549
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0078 0.0244 0.105
Brugia malayi mbt repeat family protein 0.0048 0.0124 0.0351
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0208 0.0588
Schistosoma mansoni serine/threonine protein kinase 0.0188 0.0682 0.0682
Trypanosoma cruzi DNA polymerase kappa, putative 0.0144 0.0506 0.1434
Brugia malayi nuclear hormone receptor 0.0021 0.0017 0.0048
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0233 0.1692
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0047 0.012 0.0519
Schistosoma mansoni smad1 5 8 and 0.0025 0.0031 0.0031
Loa Loa (eye worm) glutamate receptor 0.0049 0.0128 0.0551
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0208 0.0588
Onchocerca volvulus 0.0078 0.0244 0.1417
Echinococcus multilocularis g protein coupled receptor 0.0047 0.012 0.012
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0026 0.0037 0.0037
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0021 0.0017 0.0073
Loa Loa (eye worm) hypothetical protein 0.0449 0.172 0.741
Trypanosoma cruzi polo-like protein kinase, putative 0.0188 0.0682 0.193
Brugia malayi ImpB/MucB/SamB family protein 0.0116 0.0395 0.1119
Trichomonas vaginalis glutaminase, putative 0.0274 0.1025 0.7541
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0047 0.012 0.0341
Schistosoma mansoni pyruvate kinase 0.0035 0.0073 0.0073
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.012 0.012
Schistosoma mansoni scm-relatedprotein containing 4 mbt domains (sfmbt) 0.0048 0.0124 0.0124
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0078 0.0244 0.0686
Mycobacterium ulcerans hypothetical protein 0.0036 0.0077 0.0207
Echinococcus granulosus pyruvate kinase 0.0069 0.0206 0.0206
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0195 0.054
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0078 0.0244 0.0113
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.012 0.012
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0116 0.0395 0.0395
Trypanosoma cruzi small ubiquitin protein, putative 0.0051 0.0136 0.0384
Echinococcus multilocularis glutamate receptor 2 0.0045 0.0114 0.0114
Echinococcus multilocularis transcription factor Dp 1 0.0038 0.0085 0.0085
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0244 0.069
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0021 0.0016 0.0016
Onchocerca volvulus Pyruvate kinase homolog 0.0069 0.0206 0.1198
Mycobacterium tuberculosis Probable dihydroorotate dehydrogenase PyrD 0.0905 0.3533 1
Loa Loa (eye worm) pip kinase 2 0.0346 0.131 0.5646
Echinococcus granulosus glutamate receptor 2 0.0028 0.0047 0.0047
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0117 0.0397 0.1121
Echinococcus multilocularis suppression of tumorigenicity 18 protein 0.0054 0.015 0.015
Echinococcus multilocularis dro:myosuppressin receptor 0.0047 0.012 0.012
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0047 0.012 0.012
Trypanosoma brucei DNA damage repair protein, putative 0.0036 0.0077 0.0218
Brugia malayi Intermediate filament tail domain containing protein 0.0054 0.0149 0.0421
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0905 0.3533 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.012 0.012
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0047 0.012 0.012
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0021 0.0017 0.0073
Loa Loa (eye worm) histone methyltransferase 0.0065 0.0192 0.0826
Echinococcus granulosus nmda type glutamate receptor 0.0036 0.0077 0.0077
Echinococcus granulosus cathepsin l cysteine peptidase 0.0018 0.0006 0.0006
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0047 0.012 0.0341
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0244 0.069
Echinococcus granulosus beta LACTamase domain containing family member 0.0071 0.0218 0.0218
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0042 0.0099 0.0701
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0017 0.0001 0.0004
Leishmania major pyruvate kinase 0.0069 0.0206 0.058
Loa Loa (eye worm) glutaminase 0.0274 0.1025 0.4415
Brugia malayi Cyclic-nucleotide gated cation channel 0.002 0.0014 0.004
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0353 0.1339 0.9862
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.002 0.0014 0.0014
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0024 0.0029 0.0029
Echinococcus multilocularis fmrfamide receptor 0.0047 0.012 0.012
Mycobacterium leprae conserved hypothetical protein 0.0071 0.0218 0.0034
Schistosoma mansoni neuropeptide receptor 0.0047 0.012 0.012
Trypanosoma brucei hexokinase, putative 0.0078 0.0242 0.0686
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0117 0.0397 0.1121
Loa Loa (eye worm) FYVE finger-containing phosphoinositide kinase 0.0028 0.0044 0.019
Trichomonas vaginalis set domain proteins, putative 0.0241 0.0893 0.6565
Giardia lamblia Kinase, PLK 0.0188 0.0682 1
Schistosoma mansoni hypothetical protein 0.0141 0.0496 0.0496
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0088
Trypanosoma cruzi cruzipain precursor, putative 0.0069 0.0208 0.0588
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0054 0.0149 0.0641
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0208 0.0588
Loa Loa (eye worm) RecQ helicase 0.0023 0.0026 0.0111
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0028 0.0044 0.0125
Mycobacterium ulcerans extragenic suppressor protein SuhB 0.0081 0.0256 0.0714
Echinococcus granulosus neuropeptides capa receptor 0.0047 0.012 0.012
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0016 0.0016
Plasmodium falciparum LCCL domain-containing protein 0.0021 0.0018 0.0052
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0144 0.0506 0.3712
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0059 0.0168 0.1215
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0456 0.1747 0.4945
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0021 0.0017 0.0017
Toxoplasma gondii propionate-CoA ligase 0.0078 0.0244 0.069
Brugia malayi hexokinase 0.0078 0.0242 0.0686
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0081 0.0256 0.0724
Brugia malayi hypothetical protein 0.0021 0.0016 0.0045
Echinococcus granulosus cathepsin L cysteine proteinase 0.0018 0.0006 0.0006
Loa Loa (eye worm) hexokinase 0.0078 0.0242 0.1045
Onchocerca volvulus Bile acid receptor homolog 0.0021 0.0017 0.0098
Brugia malayi G protein-coupled receptor F59B2.13 0.0047 0.012 0.0341
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0141 0.0496 0.0496
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0265 0.099 0.2798
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0021 0.0017 0.0048
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0047 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0071 0.0218 0.0937
Schistosoma mansoni ATP-binding cassette transporter 0.0033 0.0065 0.0065
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.002 0.0014 0.0029
Trichomonas vaginalis conserved hypothetical protein 0.003 0.0052 0.0358
Trichomonas vaginalis chromobox protein, putative 0.0075 0.0233 0.1692
Mycobacterium ulcerans acetyl-CoA synthetase 0.0078 0.0244 0.0679
Chlamydia trachomatis pyruvate kinase 0.0069 0.0206 0.2812
Brugia malayi beta-lactamase family protein 0.0071 0.0218 0.0616
Brugia malayi MH1 domain containing protein 0.0025 0.0031 0.0089
Schistosoma mansoni hexokinase 0.0078 0.0242 0.0242
Plasmodium vivax thioredoxin reductase, putative 0.0051 0.0137 0.0387
Brugia malayi AMP-binding enzyme family protein 0.0078 0.0244 0.069
Onchocerca volvulus 0.0018 0.0006 0.0032
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0021 0.0016 0.0016
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0905 0.3533 1
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0119 0.0853
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0018 0.0004 0.0004
Schistosoma mansoni ubiquitin-like protein sumo/smt3-related 0.0051 0.0136 0.0136
Echinococcus granulosus hyperpolarization activated cyclic 0.002 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0025 0.0033 0.0144
Echinococcus granulosus hypothetical protein 0.0047 0.012 0.012
Toxoplasma gondii histone lysine methyltransferase SET1 0.0395 0.1506 0.4263
Toxoplasma gondii exonuclease III APE 0.002 0.0014 0.004
Trichomonas vaginalis antibiotic synthetase, putative 0.0078 0.0244 0.177
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0346 0.131 0.131
Schistosoma mansoni coup transcription factor 0.0021 0.0017 0.0017
Echinococcus granulosus neuropeptide receptor A26 0.0047 0.012 0.012
Echinococcus granulosus dro:myosuppressin receptor 0.0047 0.012 0.012
Echinococcus granulosus metabotropic glutamate receptor 5 0.0058 0.0165 0.0165
Brugia malayi follicle stimulating hormone receptor 0.0047 0.012 0.0341
Giardia lamblia Pyruvate kinase 0.0069 0.0206 0.2981
Schistosoma mansoni sex comb on midleg homolog 0.0048 0.0124 0.0124
Echinococcus granulosus g protein coupled receptor 0.0047 0.012 0.012
Echinococcus multilocularis hexokinase 0.0078 0.0242 0.0242
Entamoeba histolytica hypothetical protein 0.0024 0.003 0.0183
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.012 0.012
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0047 0.012 0.012
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0244 0.0679
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0195 0.054
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0018 0.0004 0.0011
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Trypanosoma cruzi phosphatidylinositol 4-phosphate 5-kinase alpha, putative 0.0028 0.0044 0.0125
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0079
Brugia malayi hypothetical protein 0.0021 0.0018 0.0052
Echinococcus granulosus neuropeptide receptor 0.0047 0.012 0.012
Echinococcus granulosus Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0028 0.0044 0.0044
Echinococcus granulosus SAM and MBT domain containing protein 0.0048 0.0124 0.0124
Toxoplasma gondii dihydroorotate dehydrogenase reveal, putative 0.0905 0.3533 1
Echinococcus multilocularis regulator of G protein signaling 3 0.0021 0.0016 0.0016
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0042 0.0099 0.028
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0021 0.0017 0.0017
Trypanosoma brucei phosphatidylinositol phosphate kinase alpha 0.0028 0.0044 0.0125
Loa Loa (eye worm) hypothetical protein 0.0078 0.0244 0.105
Echinococcus granulosus mothers against decapentaplegic 5 0.0025 0.0031 0.0031
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0346 0.131 0.131
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.002 0.0014 0.0014
Schistosoma mansoni acetyl-CoA synthetase 0.0078 0.0244 0.0244
Onchocerca volvulus Neuropeptide F receptor homolog 0.0047 0.012 0.07
Loa Loa (eye worm) MH1 domain-containing protein 0.0025 0.0031 0.0135
Brugia malayi putative neuropeptide receptor NPR1 0.0047 0.012 0.0341
Brugia malayi MH2 domain containing protein 0.0025 0.0031 0.0089
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0018 0.0018
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0047 0.012 0.012
Brugia malayi Dopamine receptor protein 2 0.0047 0.012 0.0341
Entamoeba histolytica hypothetical protein 0.0074 0.0229 0.1653
Trypanosoma brucei hypothetical protein, conserved 0.0071 0.0218 0.0616
Echinococcus granulosus polycomb protein SCMH1 0.0048 0.0124 0.0124
Echinococcus multilocularis Polycystic kidney disease protein 0.0021 0.0018 0.0018
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0265 0.099 0.2793
Brugia malayi hypothetical protein 0.0047 0.012 0.0341
Trypanosoma cruzi cysteine peptidase, putative 0.0018 0.0006 0.0016
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0021 0.0017 0.0048
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0212 0.0778 0.3354
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0073
Plasmodium vivax small ubiquitin-related modifier, putative 0.0051 0.0136 0.0384
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0358 0.1358 0.1358
Onchocerca volvulus 0.0031 0.0058 0.034
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0006 0.0011
Schistosoma mansoni metabotropic glutamate receptor 0.0042 0.0102 0.0102
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0034 0.0069 0.0478
Echinococcus granulosus g-protein coupled receptor 0.0047 0.012 0.012
Brugia malayi isocitrate dehydrogenase 0.0017 0.0001 0.0004
Onchocerca volvulus 0.0047 0.012 0.07
Echinococcus granulosus beta-adrenergic receptor kinase 0.0021 0.0018 0.0018
Brugia malayi Pyruvate kinase, muscle isozyme 0.0069 0.0206 0.0583
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0018 0.0006 0.0024
Schistosoma mansoni histamine h1 receptor 0.0047 0.012 0.012
Schistosoma mansoni RAR-like nuclear receptor 0.0021 0.0017 0.0017
Schistosoma mansoni amine GPCR 0.0047 0.012 0.012
Plasmodium falciparum zinc finger protein, putative 0.0024 0.003 0.0086
Loa Loa (eye worm) pyruvate kinase-PB 0.0048 0.0124 0.0533
Plasmodium falciparum pyruvate kinase 0.0069 0.0206 0.0583
Echinococcus granulosus lipoxygenase domain containing protein 0.0021 0.0018 0.0018
Plasmodium vivax dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0905 0.3533 1
Schistosoma mansoni neuropeptide F-like receptor 0.0047 0.012 0.012
Schistosoma mansoni glutamate receptor AMPA 0.0033 0.0065 0.0065
Trypanosoma cruzi trypanothione reductase, putative 0.0051 0.0137 0.0387
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0071 0.0218 0.0612
Schistosoma mansoni hypothetical protein 0.0017 0.0001 0.0001
Brugia malayi sulfakinin receptor protein 0.0047 0.012 0.0341
Schistosoma mansoni amine GPCR 0.0047 0.012 0.012
Plasmodium vivax pyruvate kinase 2, putative 0.0035 0.0073 0.0208
Trypanosoma brucei trypanothione reductase 0.0051 0.0137 0.0387
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.002 0.0116
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.012 0.012
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0021 0.0017 0.0017
Echinococcus granulosus neuropeptide Y receptor 0.0047 0.012 0.012
Trypanosoma brucei mitochondrial DNA polymerase beta-PAK 0.0284 0.1062 0.3006
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0337 0.0954
Loa Loa (eye worm) ctsf protein 0.0018 0.0006 0.0024
Echinococcus multilocularis serotonin receptor 0.0047 0.012 0.012
Leishmania major mitochondrial DNA polymerase beta-PAK, putative 0.0284 0.1062 0.3004
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0047 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Echinococcus multilocularis regulator of G protein signaling 0.0021 0.0016 0.0016
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.0066 0.0195 0.0547
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0078 0.0244 0.0686
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.2435 0.9621 0.9621
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0047 0.012 0.012
Mycobacterium ulcerans beta-lactamase 0.0071 0.0218 0.0605
Onchocerca volvulus 0.0047 0.012 0.07
Leishmania major 4-coumarate:coa ligase-like protein 0.0265 0.099 0.2798
Echinococcus granulosus histone acetyltransferase MYST2 0.0054 0.015 0.015
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0244 0.0679
Echinococcus granulosus histone acetyltransferase KAT2B 0.0042 0.0099 0.0099
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0244 0.0679
Trypanosoma brucei pyruvate kinase 1, putative 0.0069 0.0206 0.0583
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0034 0.007 0.0199
Schistosoma mansoni smad1 5 8 and 0.0025 0.0031 0.0031
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0506 0.1434
Schistosoma mansoni amine GPCR 0.0047 0.012 0.012
Onchocerca volvulus 0.0265 0.099 0.5754
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0105 0.0351 0.0994
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0244 0.0679
Mycobacterium tuberculosis Probable oxidoreductase 0.013 0.0449 0.1267
Echinococcus multilocularis allatostatin A receptor 0.0047 0.012 0.012
Toxoplasma gondii Erv1 / Alr family protein 0.0105 0.0351 0.0994
Schistosoma mansoni hypothetical protein 0.0021 0.0018 0.0018
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0078 0.0244 0.0244
Loa Loa (eye worm) Smad1 0.0025 0.0031 0.0135
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0017 0.0001 0.0004
Onchocerca volvulus 0.0018 0.0006 0.0032
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0061
Brugia malayi Cathepsin L-like precursor 0.0018 0.0006 0.0016
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0059 0.0168 0.1215
Mycobacterium ulcerans acyl-CoA synthetase 0.0265 0.099 0.2793
Onchocerca volvulus Huntingtin homolog 0.0122 0.042 0.2444
Echinococcus granulosus biogenic amine 5HT receptor 0.0047 0.012 0.012
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0018 0.0006 0.0006
Plasmodium falciparum glutathione reductase 0.0051 0.0137 0.0387
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0016 0.0016
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0599 0.2318 0.6561
Trichomonas vaginalis esterase, putative 0.0071 0.0218 0.1577
Schistosoma mansoni transcription factor LCR-F1 0.0074 0.0229 0.0229
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0069
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.012 0.012
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0244 0.0686
Onchocerca volvulus 0.0241 0.0893 0.5191
Loa Loa (eye worm) hypothetical protein 0.0117 0.0398 0.1715
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0006 0.0011
Brugia malayi hypothetical protein 0.0088 0.0284 0.0803
Brugia malayi regulator of G-protein signaling rgs-7 0.0021 0.0016 0.0045
Echinococcus multilocularis dna polymerase kappa 0.0144 0.0506 0.0506
Schistosoma mansoni alpha-1 adrenergic receptor 0.0047 0.012 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Brugia malayi Hexokinase family protein 0.0024 0.0029 0.0083
Brugia malayi N-terminal motif family protein 0.0176 0.0634 0.1794
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0682 0.5008
Brugia malayi glutathione reductase 0.0051 0.0137 0.0387
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0021 0.0018 0.0079
Plasmodium falciparum pyruvate kinase 2 0.0035 0.0073 0.0208
Schistosoma mansoni smad1 5 8 and 0.0025 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.1035 0.4049 0.4049
Brugia malayi hypothetical protein 0.0074 0.0229 0.0648
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0018 0.0004 0.0011
Echinococcus granulosus bloom syndrome protein 0.0023 0.0026 0.0026
Echinococcus granulosus 7tm_1 domain containing protein 0.0047 0.012 0.012
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0004 0.0011
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0006 0.0006
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0265 0.099 0.2798
Echinococcus multilocularis G-protein coupled receptor, putative 0.0047 0.012 0.012
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0078 0.0244 0.0686
Entamoeba histolytica hypothetical protein 0.0074 0.0229 0.1653
Loa Loa (eye worm) latrophilin receptor protein 2 0.0141 0.0496 0.2138
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0046 0.0115 0.0115
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0119 0.0853
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0265 0.099 0.2355
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0001 0.0004
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0014 0.0076
Treponema pallidum amino acid ABC transporter, periplasmic binding protein (hisJ) 0.0019 0.001 0.0249
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.002 0.0014 0.0029
Trypanosoma cruzi trypanothione reductase, putative 0.0018 0.0004 0.0011
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0024 0.0029 0.0029
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0071 0.0218 0.0605
Echinococcus granulosus GPCR family 2 0.0141 0.0496 0.0496
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0105 0.0351 0.0994
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0047 0.012 0.012
Echinococcus multilocularis expressed protein 0.0403 0.1538 0.1538
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.012 0.012
Echinococcus multilocularis GPCR, family 2 0.0141 0.0496 0.0496
Trypanosoma brucei DNA polymerase kappa, putative 0.0064 0.0188 0.0532
Echinococcus granulosus orexin receptor type 2 0.0047 0.012 0.012
Brugia malayi cytoplasmic intermediate filament protein 0.0029 0.0049 0.0138
Loa Loa (eye worm) glutathione reductase 0.0051 0.0137 0.059
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0047 0.012 0.012
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.06 0.2321 0.657
Onchocerca volvulus 0.0047 0.012 0.07
Mycobacterium ulcerans hypothetical protein 0.0316 0.1189 0.336
Leishmania major cathepsin L-like protease 0.0018 0.0006 0.0012
Trichomonas vaginalis ap endonuclease, putative 0.002 0.0014 0.0076
Brugia malayi Pyruvate kinase, alpha/beta domain containing protein 0.0021 0.0016 0.0045
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.0188 0.0682 0.2938
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0114 0.0814
Leishmania major hexokinase, putative 0.0078 0.0242 0.0683
Echinococcus multilocularis smad 0.0025 0.0031 0.0031
Echinococcus multilocularis calcium activated potassium channel 0.0017 0.0002 0.0002
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0284 0.1062 0.3006
Schistosoma mansoni myst-related protein 0.0024 0.003 0.003
Echinococcus multilocularis g-protein coupled receptor 0.0047 0.012 0.012
Schistosoma mansoni phosphatidylinositol-4-phosphate-5-kinaseputativ e 0.0028 0.0044 0.0044
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0077 0.0239 0.0239
Entamoeba histolytica hypothetical protein 0.0021 0.0016 0.0077
Entamoeba histolytica hexokinase 1 0.0078 0.0242 0.1752
Schistosoma mansoni Smad4 0.0025 0.0031 0.0031
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0017 0.0001 0.0001
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Brugia malayi AMP-binding enzyme family protein 0.0265 0.099 0.2801
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0006 0.0011
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0048 0.0125 0.0125
Echinococcus granulosus calcium activated potassium channel 0.0017 0.0002 0.0002
Brugia malayi Cathepsin L-like precursor 0.0018 0.0006 0.0016
Echinococcus granulosus tm gpcr rhodopsin 0.0047 0.012 0.012
Echinococcus multilocularis Smad4 0.0025 0.0031 0.0031
Entamoeba histolytica hypothetical protein 0.0074 0.0229 0.1653
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0017 0.0001 0.0001
Leishmania major phosphatidylinositol (3,5) kinase, putative 0.0028 0.0044 0.0121
Echinococcus multilocularis bloom syndrome protein 0.0023 0.0026 0.0026
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0078 0.0244 0.0244
Schistosoma mansoni cpg binding protein 0.0206 0.0754 0.0754
Echinococcus granulosus lamin dm0 0.0054 0.0149 0.0149
Schistosoma mansoni rab6-interacting 0.0021 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Entamoeba histolytica hypothetical protein 0.0031 0.0058 0.0391
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0353 0.1339 0.9862
Echinococcus multilocularis neuropeptide receptor A26 0.0047 0.012 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0037 0.0082 0.0579
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0067 0.0202 0.0202
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like, putative 0.0028 0.0044 0.0121
Schistosoma mansoni hypothetical protein 0.0141 0.0496 0.0496
Schistosoma mansoni glutaminase 0.0274 0.1025 0.1025
Schistosoma mansoni retinoic acid receptor RXR 0.0021 0.0017 0.0017
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0021 0.0017 0.0017
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0208 0.0588
Schistosoma mansoni neuropeptide f receptor 76f 0.0047 0.012 0.012
Onchocerca volvulus 0.0078 0.0242 0.141
Trypanosoma brucei unspecified product 0.0137 0.0479 0.1356
Onchocerca volvulus 0.0085 0.0274 0.1591
Brugia malayi AMP-binding enzyme family protein 0.0265 0.099 0.2801
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0208 0.0588
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0066 0.0196 0.0196
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0358 0.1358 1
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0078 0.0244 0.0113
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.002 0.0014 0.0014
Brugia malayi FYVE finger-containing phosphoinositide kinase, putative 0.0028 0.0044 0.0125
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0265 0.099 0.4263
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0029 0.005 0.0217
Trypanosoma cruzi DNA damage repair protein, putative 0.0036 0.0077 0.0218
Plasmodium vivax hypothetical protein, conserved 0.0028 0.0044 0.0125
Brugia malayi Voltage-gated potassium channel, KCNQ (Kv7-like) alpha-subunit. C. elegans kqt-1 ortholog 0.0537 0.2068 0.5854
Schistosoma mansoni lamin 0.0054 0.0149 0.0149
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0119 0.0853
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0018 0.0018
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0047 0.012 0.012
Brugia malayi acetyltransferase, GNAT family protein 0.0141 0.0496 0.1403
Brugia malayi ImpB/MucB/SamB family protein 0.0141 0.0494 0.1399
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0052 0.0142 0.0142
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0105 0.0351 0.0351
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0071 0.0218 0.0218
Trypanosoma brucei DNA polymerase IV, putative 0.0144 0.0506 0.1434
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.002 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0198 0.0723 0.2042
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0028 0.0044 0.0125
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0017 0.0048
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0018 0.0004 0.0011
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.002 0.0014 0.0037
Loa Loa (eye worm) hypothetical protein 0.0026 0.0037 0.0161
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Loa Loa (eye worm) MH2 domain-containing protein 0.0025 0.0031 0.0135
Schistosoma mansoni glutamate receptor NMDA 0.0045 0.0114 0.0114
Trypanosoma cruzi dihydroorotate dehydrogenase, putative 0.0353 0.1339 0.379
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0021 0.0017 0.0073
Leishmania major cathepsin L-like protease 0.0069 0.0208 0.0585
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0188 0.068 0.192
Schistosoma mansoni DNA polymerase eta 0.0141 0.0494 0.0494
Schistosoma mansoni ap endonuclease 0.002 0.0014 0.0014
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0017 0.0017
Schistosoma mansoni hypothetical protein 0.0047 0.012 0.012
Trypanosoma brucei DNA polymerase beta thumb, putative 0.0084 0.0269 0.0761
Brugia malayi hypothetical protein 0.0047 0.012 0.0341
Brugia malayi hypothetical protein 0.0021 0.0018 0.0052
Brugia malayi Tachykinin-like peptides receptor 99D 0.0047 0.012 0.0341
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0066 0.0196 0.0555
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0021 0.0017 0.0048
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0063 0.0184 0.0521
Loa Loa (eye worm) hypothetical protein 0.0101 0.0337 0.1453
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0042 0.0099 0.028
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0011
Leishmania major acetyl-CoA synthetase, putative 0.0078 0.0244 0.0686
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0018 0.0004 0.0007
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0047 0.012 0.0341
Loa Loa (eye worm) hypothetical protein 0.0034 0.007 0.0302
Entamoeba histolytica acyl-CoA synthetase, putative 0.0265 0.099 0.7278
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0081 0.0256 0.1851
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.002 0.0014 0.0061
Brugia malayi Cathepsin L-like precursor 0.0018 0.0006 0.0016
Loa Loa (eye worm) MBCTL1 0.0054 0.015 0.0648
Echinococcus multilocularis cysteine protease 0.0018 0.0006 0.0006
Echinococcus multilocularis lipoxygenase domain containing protein 0.0021 0.0018 0.0018
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0198 0.0723 0.2036
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0021 0.0018 0.0052
Echinococcus granulosus thioredoxin glutathione reductase 0.0051 0.0137 0.0137
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0078 0.0244 0.0113
Loa Loa (eye worm) oxidoreductase 0.0078 0.0244 0.105
Leishmania major DNA polymerase kappa, putative 0.0123 0.0423 0.1194
Echinococcus multilocularis inositol monophosphatase 1 0.0081 0.0256 0.0256
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0069 0.0206 0.058
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0119 0.0853
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0059 0.0168 0.1215
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0059 0.0168 0.1215
Echinococcus granulosus potassium voltage gated channel subfamily H 0.002 0.0014 0.0014
Echinococcus multilocularis pyruvate kinase 0.0035 0.0073 0.0073
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0188 0.068 0.192
Schistosoma mansoni myelin transcription factor 1 myt1 0.0054 0.015 0.015
Brugia malayi putative neuropeptide receptor 0.0047 0.012 0.0341
Brugia malayi hypothetical protein 0.0047 0.012 0.0341
Trypanosoma brucei unspecified product 0.008 0.0252 0.0713
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0028 0.0044 0.0044
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0119 0.0853
Brugia malayi CXXC zinc finger family protein 0.0206 0.0754 0.2134
Echinococcus granulosus biogenic amine 5HT receptor 0.0047 0.012 0.012
Mycobacterium ulcerans acyl-CoA synthetase 0.0265 0.099 0.2793
Echinococcus multilocularis somatostatin receptor 0.0047 0.012 0.012
Mycobacterium ulcerans ion transport protein 0.039 0.1486 0.4201
Echinococcus granulosus FTZ F1 alpha 0.0021 0.0017 0.0017
Brugia malayi PXA domain containing protein 0.0021 0.0016 0.0045
Loa Loa (eye worm) glutamate receptor 2 0.0033 0.0065 0.0278
Echinococcus granulosus transcription factor Dp 1 0.0038 0.0085 0.0085
Entamoeba histolytica phosphatidylinositol-4-phosphate 5-kinase, putative 0.0028 0.0044 0.0285
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0088
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0018 0.0018
Entamoeba histolytica exodeoxyribonuclease III, putative 0.002 0.0014 0.0065
Echinococcus granulosus pyruvate kinase 0.0035 0.0073 0.0073
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0028 0.0044 0.0296
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0047 0.012 0.012
Brugia malayi ecdysteroid receptor 0.0021 0.0017 0.0048
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Trypanosoma brucei ISWI complex protein 0.0022 0.002 0.0056
Loa Loa (eye worm) hypothetical protein 0.0048 0.0124 0.0534
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0066 0.0196 0.0196
Trypanosoma cruzi polo-like protein kinase, putative 0.0188 0.0682 0.193
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0141 0.0494 0.2129
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0682 0.5008
Trypanosoma brucei PAB1-binding protein , putative 0.0101 0.0337 0.0954
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0105 0.0351 0.0994
Schistosoma mansoni dihydroorotate dehydrogenase 0.0905 0.3533 0.3533
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0208 0.0588
Loa Loa (eye worm) hexokinase type II 0.0078 0.0242 0.1045
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0069
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Echinococcus multilocularis thioredoxin glutathione reductase 0.0051 0.0137 0.0137
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0244 0.0686
Brugia malayi hypothetical protein 0.0449 0.172 0.4868
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-kinase 0.0028 0.0044 0.0125
Trypanosoma brucei phosphatidylinositol-4-phosphate 5-kinase, putative 0.0028 0.0044 0.0125
Echinococcus multilocularis Small ubiquitin modifier 2 0.0051 0.0136 0.0136
Trypanosoma brucei dihydroorotate dehydrogenase (fumarate) 0.0905 0.3533 1
Brugia malayi Regulator of G protein signaling domain containing protein 0.0021 0.0016 0.0045
Mycobacterium tuberculosis Conserved protein 0.0071 0.0218 0.0612
Onchocerca volvulus 0.0017 0.0003 0.0015
Loa Loa (eye worm) hypothetical protein 0.0088 0.0284 0.1222
Onchocerca volvulus 0.0047 0.012 0.07
Giardia lamblia Sentrin 0.0051 0.0136 0.1944
Echinococcus granulosus regulator of G protein signaling 7 0.0029 0.005 0.005
Loa Loa (eye worm) hepatopoietin HPO2 0.0105 0.0351 0.1514
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0127 0.0441 0.0441
Loa Loa (eye worm) hypothetical protein 0.0031 0.0058 0.0252
Echinococcus granulosus Smad4 0.0025 0.0031 0.0031
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0117 0.0397 0.0575
Plasmodium vivax acetyl-CoA synthetase, putative 0.0078 0.0244 0.069
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0037 0.0082 0.0579
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0265 0.099 0.2355
Plasmodium falciparum DNA repair protein REV1, putative 0.0036 0.0077 0.0218
Brugia malayi serine/threonine-protein kinase plk-2 0.0188 0.0682 0.193
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.012 0.012
Schistosoma mansoni biogenic amine receptor 0.0047 0.012 0.012
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.002 0.0014 0.004
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0001 0.0001
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0021 0.0016 0.0016
Schistosoma mansoni opsin-like receptor 0.0047 0.012 0.012
Trypanosoma cruzi pyruvate kinase 2, putative 0.0069 0.0206 0.0583
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0682 0.5008
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0078 0.0244 0.0686
Leishmania major 4-coumarate:coa ligase-like protein 0.0265 0.099 0.2798
Trypanosoma cruzi hexokinase, putative 0.0078 0.0242 0.0686
Brugia malayi Papain family cysteine protease containing protein 0.0018 0.0006 0.0016
Trypanosoma cruzi major cysteine proteinase, putative 0.0054 0.0149 0.0422
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0078 0.0244 0.069
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0116 0.0395 0.0395
Brugia malayi Cathepsin L-like precursor 0.0018 0.0006 0.0016
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0244 0.0686
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0021 0.0017 0.0017
Plasmodium falciparum thioredoxin reductase 0.0051 0.0137 0.0387
Echinococcus granulosus peptide allatostatin:somatostatin 0.0047 0.012 0.012
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.0066 0.0195 0.0195
Loa Loa (eye worm) hypothetical protein 0.0078 0.0244 0.105
Schistosoma mansoni amine GPCR 0.0047 0.012 0.012
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0358 0.1358 0.1358
Schistosoma mansoni chromobox protein 0.0075 0.0233 0.0233
Schistosoma mansoni metabotropic glutamate receptor 2 3 (mglur group 2) 0.0046 0.0115 0.0115
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0069
Echinococcus granulosus allatostatin A receptor 0.0047 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0071 0.0218 0.0937
Loa Loa (eye worm) hypothetical protein 0.0069 0.0206 0.0888
Loa Loa (eye worm) neuropeptide F receptor 0.0047 0.012 0.0519
Loa Loa (eye worm) hypothetical protein 0.0048 0.0124 0.0533
Echinococcus multilocularis neuropeptide Y receptor 0.0047 0.012 0.012
Brugia malayi Heterochromatin protein 1 0.0075 0.0233 0.066
Loa Loa (eye worm) steroid hormone receptor 0.0021 0.0017 0.0073
Onchocerca volvulus 0.0047 0.012 0.07
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.012 0.012
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0048 0.0048
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.013 0.0449 0.073
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.007 0.007
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0078 0.0244 0.0679
Loa Loa (eye worm) inositol-1 0.0081 0.0256 0.1102
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0059 0.0168 0.1215
Echinococcus multilocularis axis inhibition protein axin 0.0021 0.0016 0.0016
Echinococcus multilocularis metabotropic glutamate receptor 5 0.0058 0.0165 0.0165
Brugia malayi Cathepsin L-like precursor 0.0018 0.0006 0.0016
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0141 0.0496 0.0496
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0244 0.0679
Echinococcus granulosus phosphatidylinositol phosphate 5 kinase type III 0.0028 0.0044 0.0044
Brugia malayi hypothetical protein 0.0047 0.012 0.0341
Echinococcus multilocularis neuropeptides capa receptor 0.0047 0.012 0.012
Brugia malayi CHD4 protein 0.0024 0.0029 0.0083
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.013 0.0449 0.1267
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0077 0.0239 0.0239
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.012 0.012
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0018 0.0006 0.0011
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0047 0.012 0.012
Echinococcus multilocularis pyruvate kinase 0.0035 0.0073 0.0073
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0021 0.0017 0.0017
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0105 0.0351 0.0994
Loa Loa (eye worm) hypothetical protein 0.0033 0.0065 0.0281
Echinococcus multilocularis chromobox protein 1 0.0075 0.0233 0.0233
Brugia malayi beta-lactamase 0.0071 0.0218 0.0616
Loa Loa (eye worm) receptor family ligand binding region containing protein 0.0019 0.0009 0.0039
Echinococcus granulosus intermediate filament protein 0.0054 0.0149 0.0149
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.012 0.012
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.002 0.0014 0.0037
Plasmodium vivax acyl-CoA synthetase, putative 0.0198 0.0723 0.2046
Trichomonas vaginalis conserved hypothetical protein 0.0051 0.0136 0.0973
Schistosoma mansoni glutamate receptor kainate 0.0064 0.0189 0.0189
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0021 0.0016 0.0016
Entamoeba histolytica acetyltransferase, GNAT family 0.0038 0.0085 0.0588
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0078 0.0244 0.069
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.012 0.012
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0016 0.0016
Schistosoma mansoni neuropeptide F-like receptor 0.0047 0.012 0.012
Leishmania major mitochondrial DNA polymerase beta 0.0599 0.2318 0.656
Schistosoma mansoni regulator of G protein signaling 0.0021 0.0016 0.0016
Toxoplasma gondii LsmAD domain-containing protein 0.0101 0.0337 0.0954
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.002 0.0014 0.0014
Brugia malayi hypothetical protein 0.0101 0.0337 0.0954
Brugia malayi Nuclear hormone receptor-like 1 0.0021 0.0017 0.0048
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0265 0.099 0.2793
Loa Loa (eye worm) hypothetical protein 0.0122 0.042 0.1811
Plasmodium falciparum glutathione reductase 0.0018 0.0004 0.0011
Schistosoma mansoni voltage-gated potassium channel KCNQ 0.0537 0.2068 0.2068
Loa Loa (eye worm) CXXC zinc finger family protein 0.0206 0.0754 0.3248
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0198 0.0723 1
Trypanosoma cruzi DNA polymerase kappa, putative 0.0144 0.0506 0.1434
Echinococcus granulosus Polycystic kidney disease protein 0.0021 0.0018 0.0018
Echinococcus granulosus phosphatidylinositol 5 phosphate 4 kinase type 2 0.0346 0.131 0.131
Echinococcus granulosus hexokinase 0.0078 0.0242 0.0242
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0007
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0074 0.0229 0.0229
Brugia malayi beta-lactamase family protein 0.0071 0.0218 0.0616
Leishmania major cathepsin L-like protease 0.0018 0.0006 0.0012
Echinococcus multilocularis Phosphatidylinositol 4 phosphate 5 kinase type 1 0.0028 0.0044 0.0044
Echinococcus multilocularis g protein coupled receptor 0.0047 0.012 0.012
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0017 0.0001 0.0001
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0025 0.0031 0.0031
Plasmodium vivax vivapain-2 0.0018 0.0006 0.0016
Echinococcus multilocularis cathepsin L cysteine protease 0.0018 0.0006 0.0006
Trypanosoma cruzi hypothetical protein, conserved 0.0071 0.0218 0.0616
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0208 0.0588
Echinococcus granulosus inositol monophosphatase 1 0.0081 0.0256 0.0256
Onchocerca volvulus 0.0047 0.012 0.07
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0353 0.1339 0.9862
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0047 0.012 0.0341
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0208 0.0588
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0081 0.0256 0.0721
Mycobacterium tuberculosis Inositol-1-monophosphatase SuhB 0.0073 0.0222 0.0625
Echinococcus granulosus alpha 1A adrenergic receptor 0.0047 0.012 0.012
Brugia malayi SET domain containing protein 0.0018 0.0005 0.0014
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.002 0.0014 0.0014
Schistosoma mansoni growth hormone secretagogue receptor 0.0047 0.012 0.012
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0304 0.2216
Echinococcus granulosus g protein coupled receptor 0.0047 0.012 0.012
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0001 0.0004
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0011
Entamoeba histolytica hypothetical protein 0.0021 0.0016 0.0077
Brugia malayi mbt repeat family protein 0.0048 0.0124 0.0351
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0045 0.0114 0.0114
Onchocerca volvulus 0.0054 0.0149 0.0865
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0905 0.3533 1
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0244 0.0679
Chlamydia trachomatis arginine ABC transporter substrate-binding protein ArtJ 0.0019 0.001 0.0083
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0066 0.0196 0.1408
Loa Loa (eye worm) hypothetical protein 0.0198 0.0723 0.3113
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.012 0.012
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase type II beta, putative 0.0028 0.0044 0.0125
Brugia malayi hypothetical protein 0.0047 0.012 0.0341
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0029 0.0049 0.021
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0017 0.0001 0.0004
Brugia malayi Dihydroorotate dehydrogenase, mitochondrial precursor, putative 0.0905 0.3533 1
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0018 0.0004 0.0011
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.012 0.012
Leishmania major hypothetical protein, conserved 0.0071 0.0218 0.0612
Mycobacterium tuberculosis Probable lipase LipD 0.0071 0.0218 0.0612
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Leishmania major DNA polymerase kappa, putative 0.0036 0.0077 0.0214
Schistosoma mansoni blooms syndrome DNA helicase 0.0018 0.0006 0.0006
Trypanosoma brucei hexokinase 0.0078 0.0242 0.0686
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0078 0.0244 0.0679
Loa Loa (eye worm) pyruvate kinase 0.0069 0.0206 0.0888
Mycobacterium leprae Probable dihydroorotate dehydrogenase PyrD 0.0905 0.3533 1
Mycobacterium ulcerans esterase/lipase LipP 0.0071 0.0218 0.0605
Echinococcus multilocularis beta LACTamase domain containing family member 0.0071 0.0218 0.0218
Loa Loa (eye worm) beta-lactamase 0.0071 0.0218 0.0937
Onchocerca volvulus Cathepsin L homolog 0.0018 0.0006 0.0032
Trypanosoma cruzi cysteine peptidase, putative 0.0069 0.0208 0.0588
Trypanosoma brucei DNA polymerase IV, putative 0.0144 0.0506 0.1434
Brugia malayi polk-prov protein 0.0064 0.0188 0.0532
Entamoeba histolytica ubiquitin like protein 0.0051 0.0136 0.0963
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0048 0.0125 0.0125
Echinococcus granulosus serotonin receptor 0.0047 0.012 0.012
Loa Loa (eye worm) intermediate filament protein 0.0054 0.0149 0.0641
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.002 0.0014 0.0152
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0021 0.0017 0.0073
Entamoeba histolytica serine/threonine protein kinase, putative 0.0188 0.0682 0.5002
Brugia malayi RE15519p 0.0047 0.012 0.0341
Leishmania major DNA polymerase eta, putative 0.0061 0.0176 0.0494
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Schistosoma mansoni amine GPCR 0.0047 0.012 0.012
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0078 0.0244 0.069
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0358 0.1358 0.1358
Schistosoma mansoni SET domain protein 0.0017 0.0003 0.0003
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.002 0.0014 0.0061
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0048 0.0125 0.0125
Echinococcus granulosus cyclic nucleotide gated cation channel 0.002 0.0014 0.0014
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0078 0.0244 0.069
Schistosoma mansoni pyruvate kinase 0.0069 0.0206 0.0206
Brugia malayi SET domain containing protein 0.0017 0.0003 0.0008
Echinococcus granulosus geminin 0.1035 0.4049 0.4049
Trypanosoma cruzi phosphatidylinositol-4-phosphate 5-kinase, putative 0.0028 0.0044 0.0125
Brugia malayi G-protein coupled receptor 0.0047 0.012 0.0341
Plasmodium vivax phosphatidylinositol-4-phosphate 5-kinase, putative 0.0028 0.0044 0.0125
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0077 0.0239 0.0239
Brugia malayi Zinc finger, C2H2 type family protein 0.0353 0.1339 0.379
Schistosoma mansoni phosphatidylinositol-4-phosphate 5-kinase type II 0.0028 0.0044 0.0044
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0047 0.0119 0.0119
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Mycobacterium tuberculosis Probable dehydrogenase 0.0117 0.0397 0.1121
Loa Loa (eye worm) hypothetical protein 0.0054 0.0149 0.0641
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0017 0.0001 0.0001
Echinococcus multilocularis Protein lozenge 0.0056 0.0158 0.0158
Brugia malayi Cathepsin L-like precursor 0.0018 0.0006 0.0016
Leishmania major cathepsin L-like protease 0.0069 0.0208 0.0585
Brugia malayi exodeoxyribonuclease III family protein 0.002 0.0014 0.004
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0052 0.0142 0.0142
Echinococcus granulosus TGF beta signal transducer SmadC 0.0025 0.0031 0.0031
Echinococcus granulosus pyruvate kinase 0.0035 0.0073 0.0073
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0069
Brugia malayi hypothetical protein 0.0047 0.012 0.0341
Toxoplasma gondii ABC1 family protein 0.0071 0.0218 0.0616
Echinococcus multilocularis orexin receptor type 2 0.0047 0.012 0.012
Brugia malayi neuropeptide F receptor 0.0047 0.012 0.0341
Trichomonas vaginalis CAMK family protein kinase 0.0093 0.0304 0.2216
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0078 0.0244 0.0679
Trypanosoma cruzi mitochondrial DNA polymerase beta, putative 0.0599 0.2318 0.6561
Schistosoma mansoni myst-related protein 0.0024 0.003 0.003
Brugia malayi Dopamine receptor 0.0047 0.012 0.0341
Trichomonas vaginalis penicillin-binding protein, putative 0.0071 0.0218 0.1577
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0506 0.1434
Schistosoma mansoni serine/threonine protein kinase 0.0021 0.0018 0.0018
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.012 0.012
Mycobacterium tuberculosis Conserved hypothetical protein 0.0116 0.0395 0.1116
Loa Loa (eye worm) hypothetical protein 0.0071 0.0218 0.0937
Loa Loa (eye worm) hypothetical protein 0.0176 0.0634 0.273
Echinococcus multilocularis beta adrenergic receptor kinase 0.0021 0.0018 0.0018
Brugia malayi Serotonin receptor 0.0047 0.012 0.0341
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Toxoplasma gondii thioredoxin reductase 0.0051 0.0137 0.0387
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0007
Loa Loa (eye worm) hypothetical protein 0.0021 0.0018 0.0079
Mycobacterium ulcerans hypothetical protein 0.0071 0.0218 0.0605
Schistosoma mansoni neuropeptide receptor 0.0047 0.012 0.012
Entamoeba histolytica deoxycytidyl transferase, putative 0.0116 0.0395 0.2883
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0078 0.0244 0.0686
Entamoeba histolytica acyl-coA synthetase, putative 0.0265 0.099 0.7278
Echinococcus multilocularis potassium voltage gated channel subfamily KQT 0.0537 0.2068 0.2068
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0017 0.0048
Echinococcus granulosus voltage gated potassium channel 0.002 0.0014 0.0014
Echinococcus granulosus hexokinase 0.0078 0.0242 0.0242
Trichomonas vaginalis conserved hypothetical protein 0.0022 0.002 0.0116
Leishmania major cathepsin L-like protease 0.0018 0.0006 0.0012
Schistosoma mansoni terminal deoxycytidyl transferase 0.0116 0.0395 0.0395
Brugia malayi Thioredoxin reductase 0.0051 0.0137 0.0387
Mycobacterium ulcerans acyl-CoA synthetase 0.0078 0.0244 0.0679
Plasmodium falciparum small ubiquitin-related modifier 0.0051 0.0136 0.0384
Echinococcus granulosus ecdysone induced protein 78C 0.0021 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0081 0.0256 0.0714
Schistosoma mansoni neuropeptide receptor 0.0047 0.012 0.012
Brugia malayi Hexokinase family protein 0.0078 0.0242 0.0686
Echinococcus granulosus neuropeptide FF receptor 2 0.0047 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0122 0.042 0.1811
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Schistosoma mansoni cathepsin F (C01 family) 0.0018 0.0006 0.0006
Echinococcus multilocularis ubiquitin 0.0031 0.0058 0.0058
Giardia lamblia Phosphatidylinositol-4-phosphate 5-kinase, putative 0.0028 0.0044 0.0591
Brugia malayi Augmenter of liver regeneration 0.0105 0.0351 0.0994
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0195 0.0195
Brugia malayi hypothetical protein 0.0047 0.012 0.0341
Plasmodium vivax vivapain-2 0.0018 0.0006 0.0016
Echinococcus granulosus serine:threonine protein kinase PLK1 0.0188 0.0682 0.0682
Mycobacterium tuberculosis Probable lipase LipE 0.0071 0.0218 0.0612
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0088
Echinococcus multilocularis neuropeptides capa receptor 0.0047 0.012 0.012
Brugia malayi hypothetical protein 0.0047 0.012 0.0341
Plasmodium falciparum histone acetyltransferase GCN5 0.0038 0.0085 0.0241
Toxoplasma gondii isocitrate dehydrogenase 0.0017 0.0001 0.0004
Schistosoma mansoni hypothetical protein 0.0074 0.0229 0.0229
Echinococcus multilocularis hyperpolarization activated cyclic 0.002 0.0014 0.0014
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Schistosoma mansoni polycystin 1-related 0.0021 0.0018 0.0018
Echinococcus granulosus dna polymerase eta 0.0141 0.0494 0.0494
Wolbachia endosymbiont of Brugia malayi dihydroorotate dehydrogenase 2 0.0905 0.3533 1
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.0188 0.0682 0.0682
Schistosoma mansoni glutamate receptor AMPA 0.0033 0.0065 0.0065
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0019 0.001 0.0017
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0047 0.012 0.0519
Echinococcus multilocularis glutamate receptor 2 0.0033 0.0065 0.0065
Loa Loa (eye worm) hypothetical protein 0.0265 0.099 0.4263
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0077 0.0239 0.0239
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0047 0.012 0.012
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0208 0.0588
Loa Loa (eye worm) thioredoxin reductase 0.0051 0.0137 0.059
Brugia malayi Serotonin receptor 0.0047 0.012 0.0341
Trypanosoma brucei DNA damage repair protein, putative 0.0036 0.0077 0.0218
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0506 0.1434
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0088
Leishmania major small ubiquitin protein, putative 0.0051 0.0136 0.0381
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.002 0.0014 0.0014
Onchocerca volvulus 0.0449 0.172 1
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0078 0.0244 0.0679
Echinococcus multilocularis neuropeptide Y receptor 0.0047 0.012 0.012
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0084 0.0269 0.0761
Brugia malayi Pyruvate kinase, M2 isozyme 0.0069 0.0206 0.0583
Brugia malayi hypothetical protein 0.0031 0.0058 0.0165
Echinococcus multilocularis phosphatidylinositol 5 phosphate 4 kinase type 2 0.0346 0.131 0.131
Leishmania major acetyl-CoA synthetase, putative 0.0078 0.0244 0.0686
Onchocerca volvulus Pyruvate kinase homolog 0.0069 0.0206 0.1198
Onchocerca volvulus 0.0047 0.0119 0.0693
Loa Loa (eye worm) acetyltransferase 0.0141 0.0496 0.2135
Brugia malayi F/Y-rich N-terminus family protein 0.0064 0.0189 0.0534
Brugia malayi Hexokinase family protein 0.0049 0.0127 0.0361
Trichomonas vaginalis conserved hypothetical protein 0.0047 0.0119 0.0853
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0047 0.012 0.012
Loa Loa (eye worm) hypothetical protein 0.0071 0.0218 0.0937
Echinococcus multilocularis regulator of G protein signaling 7 0.0029 0.005 0.005
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0047 0.012 0.012
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0021 0.0017 0.0048
Schistosoma mansoni z-protein (S1r protein) 0.0029 0.005 0.005
Loa Loa (eye worm) hypothetical protein 0.0449 0.172 0.741
Schistosoma mansoni lipoxygenase 0.0127 0.0441 0.0441
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Brugia malayi regulator of G-protein signaling egl-10 0.0029 0.005 0.0143
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0208 0.0588
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0025 0.0031 0.0031
Schistosoma mansoni hypothetical protein 0.0047 0.012 0.012
Schistosoma mansoni hypothetical protein 0.0046 0.0115 0.0115
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0078 0.0244 0.069
Schistosoma mansoni cpg binding protein 0.0218 0.0801 0.0801
Loa Loa (eye worm) G-protein coupled receptor 0.0047 0.012 0.0519
Schistosoma mansoni aldehyde dehydrogenase 0.0066 0.0195 0.0195
Echinococcus granulosus axis inhibition protein axin 0.0021 0.0016 0.0016
Echinococcus multilocularis dnaJ subfamily B 0.2531 1 1
Schistosoma mansoni chromobox protein 0.0075 0.0233 0.0233
Brugia malayi GnHR receptor homolog 0.0047 0.012 0.0341
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Onchocerca volvulus Cathepsin F homolog 0.0018 0.0006 0.0032
Brugia malayi C2-HC type zinc finger protein C.e-MyT1 0.0054 0.015 0.0426
Echinococcus granulosus smad 0.0025 0.0031 0.0031
Echinococcus granulosus pyruvate kinase 0.0069 0.0206 0.0206
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0073
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0295 0.1106 0.1106
Leishmania major phosphatidylinositol-4-phosphate-5-kinase-likep ro tein 0.0028 0.0044 0.0121
Echinococcus granulosus hexokinase 0.0078 0.0242 0.0242
Echinococcus multilocularis neuropeptide FF receptor 2 0.0047 0.012 0.012
Schistosoma mansoni glutamate receptor kainate 0.0064 0.0189 0.0189
Loa Loa (eye worm) hypothetical protein 0.002 0.0014 0.0061
Brugia malayi A-kinase anchor protein 10, precursor 0.0021 0.0016 0.0045
Echinococcus granulosus G protein coupled receptor 139 0.0047 0.012 0.012
Brugia malayi Inositol-1 0.0081 0.0256 0.0724
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0078 0.0244 0.0679
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0073
Toxoplasma gondii phosphatidylinositol-4-phosphate 5-Kinase 0.0028 0.0044 0.0125
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0127 0.0441 0.0441
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0042 0.0101 0.059
Toxoplasma gondii pyruvate kinase PyK1 0.0069 0.0206 0.0583
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0078 0.0244 0.069
Brugia malayi G protein-coupled receptor 0.0047 0.012 0.0341
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0017 0.0017
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.002 0.0014 0.004
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0196 0.0555
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0047 0.012 0.012
Trichomonas vaginalis conserved hypothetical protein 0.0021 0.0016 0.0088
Trypanosoma cruzi DNA polymerase beta thumb, putative 0.0084 0.0269 0.0761
Onchocerca volvulus 0.0078 0.0242 0.141
Loa Loa (eye worm) hypothetical protein 0.0346 0.131 0.5646
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0018 0.0006 0.0024
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0045 0.0114 0.0114
Brugia malayi Bloom's syndrome protein homolog 0.0023 0.0026 0.0073
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0494 0.0494
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0047 0.012 0.012
Onchocerca volvulus Heterochromatin protein 1 homolog 0.0045 0.0114 0.0664
Trypanosoma brucei pyruvate kinase 1 0.0069 0.0206 0.0583
Echinococcus multilocularis cpg binding protein 0.0218 0.0801 0.0801
Echinococcus multilocularis SAM and MBT domain containing protein 0.0048 0.0124 0.0124
Echinococcus multilocularis geminin 0.1035 0.4049 0.4049
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0066 0.0196 0.0551
Onchocerca volvulus 0.0018 0.0006 0.0032
Schistosoma mansoni opsin-like receptor 0.0047 0.012 0.012
Echinococcus multilocularis hexokinase 0.0078 0.0242 0.0242
Onchocerca volvulus 0.0018 0.0006 0.0032
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0047 0.012 0.012
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0047 0.012 0.012
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0017 0.0001 0.0004
Echinococcus granulosus neuropeptide s receptor 0.0047 0.012 0.012
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0066 0.0196 0.0196
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.012 0.012
Brugia malayi Latrophilin receptor protein 2 0.0141 0.0496 0.1405
Schistosoma mansoni kinase 0.0096 0.0314 0.0314
Leishmania major phosphatidylinositol-4-phosphate 5-kinase-like protein 0.0028 0.0044 0.0121
Loa Loa (eye worm) hypothetical protein 0.0088 0.0284 0.1222
Brugia malayi Metabotropic glutamate receptor precursor. 0.0049 0.0128 0.0362
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0141 0.0494 0.0494
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.002 0.0014 0.004
Brugia malayi Ubiquitin-like protein SMT3 0.0051 0.0136 0.0384
Loa Loa (eye worm) hypothetical protein 0.0021 0.0016 0.0069
Loa Loa (eye worm) glutaminase 2 0.0274 0.1025 0.4415
Echinococcus multilocularis isocitrate dehydrogenase 0.0017 0.0001 0.0001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0047 0.012 0.012
Echinococcus granulosus chromobox protein 1 0.0075 0.0233 0.0233
Plasmodium falciparum ataxin-2 like protein, putative 0.0101 0.0337 0.0954
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0018 0.0004 0.0004
Loa Loa (eye worm) neuropeptide F receptor 0.0047 0.012 0.0519
Echinococcus multilocularis rhodopsin orphan GPCR 0.0047 0.012 0.012
Loa Loa (eye worm) G-protein coupled receptor 0.0047 0.012 0.0519
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0141 0.0496 0.0496
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0059 0.0168 0.1215
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0017 0.0001 0.0001
Echinococcus multilocularis cysteine protease 0.0018 0.0006 0.0006
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Loa Loa (eye worm) hypothetical protein 0.0141 0.0496 0.2138
Brugia malayi hypothetical protein 0.0065 0.0194 0.055
Loa Loa (eye worm) hypothetical protein 0.0265 0.099 0.4263
Loa Loa (eye worm) hypothetical protein 0.0054 0.015 0.0648
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0506 0.1434
Loa Loa (eye worm) PXA domain-containing protein 0.0021 0.0016 0.0069
Loa Loa (eye worm) hypothetical protein 0.0021 0.0017 0.0073
Echinococcus multilocularis Regulator of G protein signaling 20 0.0021 0.0016 0.0016
Schistosoma mansoni hypothetical protein 0.0295 0.1107 0.1107
Leishmania major pyruvate kinase 0.0069 0.0206 0.058
Echinococcus granulosus glutamate NMDA receptor subunit 0.0089 0.0286 0.0286
Echinococcus granulosus cyclic nucleotide gated cation channel 0.002 0.0014 0.0014
Entamoeba histolytica hypothetical protein 0.0074 0.0229 0.1653
Loa Loa (eye worm) pip kinase 1 0.0028 0.0044 0.019
Onchocerca volvulus 0.0206 0.0754 0.4384
Loa Loa (eye worm) transcription factor SMAD2 0.0361 0.1368 0.5894
Mycobacterium tuberculosis Conserved hypothetical protein 0.0316 0.1189 0.3365
Echinococcus granulosus fmrfamide receptor 0.0047 0.012 0.012
Echinococcus multilocularis microtubule associated protein 2 0.1385 0.5444 0.5444
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0141 0.0496 0.1405
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0021 0.0016 0.0088
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.002 0.0015 0.0041
Trypanosoma cruzi DNA polymerase eta, putative 0.0141 0.0494 0.1399
Leishmania major dihydroorotate dehydrogenase 0.0905 0.3533 1
Brugia malayi AKH receptor 0.0047 0.012 0.0341
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0047 0.012 0.012
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0071 0.0218 0.0612
Plasmodium falciparum dihydroorotate dehydrogenase 0.0905 0.3533 1
Echinococcus multilocularis g protein coupled receptor 0.0047 0.012 0.012
Echinococcus granulosus rhodopsin orphan GPCR 0.0047 0.012 0.012
Brugia malayi Melatonin receptor type 1A 0.0047 0.012 0.0341
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0188 0.068 0.192
Brugia malayi latrophilin 2 splice variant baaae 0.0306 0.1149 0.3253
Onchocerca volvulus 0.0018 0.0006 0.0032
Loa Loa (eye worm) FYVE zinc finger family protein 0.0028 0.0044 0.019
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0071 0.0218 0.0937
Treponema pallidum exodeoxyribonuclease (exoA) 0.002 0.0014 0.0431
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0188 0.068 0.192
Onchocerca volvulus Serine\/threonine kinase homolog 0.0188 0.0682 0.3965
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0018 0.0006 0.0011
Loa Loa (eye worm) heterochromatin protein 1 0.0075 0.0233 0.1004
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.002 0.0014 0.0014
Echinococcus multilocularis G protein coupled receptor 139 0.0047 0.012 0.012
Brugia malayi AMP-binding enzyme family protein 0.0265 0.099 0.2801
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0006 0.0011
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0353 0.1339 0.9862
Brugia malayi G-protein coupled receptor 0.0047 0.012 0.0341
Plasmodium falciparum acyl-CoA synthetase 0.0198 0.0723 0.2046
Brugia malayi intermediate filament protein 0.0054 0.0149 0.0421
Chlamydia trachomatis glutamine binding protein 0.0019 0.001 0.0083
Echinococcus granulosus histone acetyltransferase KAT2B 0.0137 0.048 0.048
Onchocerca volvulus 0.0078 0.0244 0.1417
Loa Loa (eye worm) fibroinase 0.0018 0.0006 0.0024
Mycobacterium tuberculosis Probable esterase LipL 0.0071 0.0218 0.0612
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0506 0.1434
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0021 0.0017 0.0017
Mycobacterium tuberculosis Probable hydrolase 0.0071 0.0218 0.0612
Trypanosoma brucei DNA polymerase kappa, putative 0.0144 0.0506 0.1434
Loa Loa (eye worm) glutamate receptor 1 0.0033 0.0065 0.0278
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0089 0.0286 0.0286
Trypanosoma cruzi DNA polymerase kappa, putative 0.0144 0.0506 0.1434
Onchocerca volvulus 0.0047 0.012 0.07
Toxoplasma gondii NADPH-glutathione reductase 0.0018 0.0004 0.0011
Loa Loa (eye worm) CHromoDomain protein family member 0.0024 0.0029 0.0127
Echinococcus granulosus regulator of G protein signaling 3 0.0021 0.0016 0.0016
Trichomonas vaginalis D-aminoacylase, putative 0.0071 0.0218 0.1577
Echinococcus granulosus potassium channel KvQLT family member kqt 1 0.0537 0.2068 0.2068
Trypanosoma brucei phosphatidylinositol (3,5) kinase, putative 0.0028 0.0044 0.0125
Echinococcus granulosus pyruvate kinase 0.0035 0.0073 0.0073
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0067 0.0201 0.0564
Loa Loa (eye worm) SMO-1 protein 0.0051 0.0136 0.0585
Loa Loa (eye worm) hypothetical protein 0.0071 0.0218 0.0937
Mycobacterium ulcerans lipase LipD 0.0071 0.0218 0.0605
Loa Loa (eye worm) hypothetical protein 0.06 0.2321 1
Echinococcus granulosus dna polymerase kappa 0.0144 0.0506 0.0506
Trichomonas vaginalis hypothetical protein 0.0025 0.0033 0.0216
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0078 0.0244 0.0679
Onchocerca volvulus 0.0346 0.131 0.762
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0021 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0198 0.0723 0.3113
Echinococcus granulosus Small ubiquitin modifier 2 0.0051 0.0136 0.0136
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0021 0.0017 0.0017
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0077 0.0218
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0101 0.072
Mycobacterium leprae possible inositol monophosphatase SubH (IMPase) (inositol-1-phosphatase) (I-1-Pase ). 0.0073 0.0222 0.0048
Leishmania major hexokinase, putative 0.0078 0.0242 0.0683
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Onchocerca volvulus 0.0047 0.012 0.07
Loa Loa (eye worm) TYRA-2 protein 0.0047 0.012 0.0519
Trypanosoma brucei small ubiquitin-related modifier 0.0051 0.0136 0.0384
Schistosoma mansoni axis inhibition protein axin 0.0021 0.0016 0.0016
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.028 0.0792
Echinococcus granulosus cpg binding protein 0.0218 0.0801 0.0801
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0052 0.0142 0.0142
Mycobacterium ulcerans acyl-CoA synthetase 0.0265 0.099 0.2793
Giardia lamblia DNA damage repair protein 0.0036 0.0077 0.1075
Onchocerca volvulus 0.0047 0.012 0.07
Schistosoma mansoni neuropeptide receptor 0.0047 0.012 0.012
Mycobacterium tuberculosis Probable reductase 0.0117 0.0397 0.1121
Trypanosoma brucei unspecified product 0.008 0.0252 0.0713
Loa Loa (eye worm) hypothetical protein 0.0064 0.0188 0.081
Echinococcus multilocularis hexokinase type 2 0.0078 0.0242 0.0242
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0066 0.0196 0.0555
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0117 0.0397 0.1121
Schistosoma mansoni hypothetical protein 0.0141 0.0496 0.0496
Schistosoma mansoni hypothetical protein 0.2531 1 1
Trypanosoma brucei DNA polymerase kappa, putative 0.0087 0.028 0.0792
Brugia malayi larval opioid receptor 0.0047 0.012 0.0341
Trypanosoma brucei polo-like protein kinase 0.0188 0.0682 0.193
Brugia malayi hypothetical protein 0.0047 0.012 0.0341
Trichomonas vaginalis inositol monophosphatase, putative 0.0081 0.0256 0.186
Schistosoma mansoni lipoxygenase 0.0089 0.0288 0.0288
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0018 0.0006 0.0011
Echinococcus granulosus potassium voltage gated channel subfamily H 0.002 0.0014 0.0014
Brugia malayi MH2 domain containing protein 0.0361 0.1368 0.3873
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0021 0.0017 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0021 0.0017 0.0048
Loa Loa (eye worm) metabotropic GABA-B receptor subtype 2 0.0019 0.0009 0.0039
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0141 0.0494 0.0494
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0019 0.001 0.0024
Echinococcus granulosus cathepsin l1 0.0018 0.0006 0.0006
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0018 0.0006 0.0024
Trypanosoma cruzi ISWI complex protein 0.0022 0.002 0.0056
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0034 0.007 0.007
Loa Loa (eye worm) hypothetical protein 0.0053 0.0145 0.0624
Schistosoma mansoni thyroid hormone receptor 0.0021 0.0017 0.0017
Loa Loa (eye worm) hypothetical protein 0.0053 0.0144 0.0622
Trypanosoma cruzi mitochondrial DNA polymerase beta-PAK, putative 0.0103 0.0342 0.0969
Loa Loa (eye worm) isocitrate dehydrogenase 0.0017 0.0001 0.0006
Toxoplasma gondii BRCA1 C Terminus (BRCT) domain-containing protein 0.0043 0.0104 0.0296
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0018 0.0004 0.0011
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0017 0.0001 0.0001
Trypanosoma cruzi PAB1-binding protein , putative 0.0101 0.0337 0.0954
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0018 0.0004 0.0007
Echinococcus multilocularis mothers against decapentaplegic 5 0.0025 0.0031 0.0031
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0052 0.0142 0.0142
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0051 0.0137 0.0384
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0193 0.07 0.07
Echinococcus granulosus ubiquitin 0.0031 0.0058 0.0058
Mycobacterium leprae Probable lipase LipE 0.0071 0.0218 0.0034
Trypanosoma cruzi dihydroorotate dehydrogenase (fumarate), putative 0.0905 0.3533 1
Brugia malayi Isocitrate dehydrogenase 0.0017 0.0001 0.0004
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.002 0.0014 0.0062
Entamoeba histolytica hexokinase 2 0.0078 0.0242 0.1752
Plasmodium vivax hypothetical protein, conserved 0.0071 0.0218 0.0616
Echinococcus multilocularis neuropeptide receptor 0.0047 0.012 0.012
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0031 0.0056 0.0056
Loa Loa (eye worm) hypothetical protein 0.0019 0.0009 0.0039
Echinococcus multilocularis phosphatidylinositol phosphate 5 kinase type III 0.0028 0.0044 0.0044
Trichomonas vaginalis DNA helicase recq1, putative 0.0023 0.0026 0.0161
Schistosoma mansoni cpg binding protein 0.0218 0.0801 0.0801
Brugia malayi hexokinase type II 0.0025 0.0032 0.009
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0046 0.0115 0.0115
Onchocerca volvulus 0.0048 0.0124 0.0721
Echinococcus multilocularis polycomb protein SCMH1 0.0048 0.0124 0.0124
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0078 0.0244 0.069
Trichomonas vaginalis pyruvate kinase, putative 0.0069 0.0206 0.1493
Schistosoma mansoni ap endonuclease 0.002 0.0014 0.0014
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.0066 0.0195 0.0547
Mycobacterium ulcerans DNA polymerase IV 0.0144 0.0506 0.1424
Schistosoma mansoni loxhd1 0.0021 0.0018 0.0018
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0141 0.0494 0.2128
Echinococcus granulosus neuropeptide Y receptor 0.0047 0.012 0.012
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0078 0.0244 0.0679
Loa Loa (eye worm) runx1 0.0056 0.0158 0.0679
Mycobacterium ulcerans aldehyde dehydrogenase 0.0066 0.0195 0.054
Onchocerca volvulus 0.0021 0.0018 0.0107
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Loa Loa (eye worm) melatonin receptor type 1A 0.0047 0.012 0.0519
Echinococcus granulosus glutamate receptor subunit protein glur 0.0017 0.0001 0.0001
Echinococcus granulosus mixed lineage leukemia protein mll 0.0052 0.0142 0.0142
Echinococcus multilocularis lamin dm0 0.0054 0.0149 0.0149
Brugia malayi hypothetical protein 0.0122 0.042 0.119
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0018 0.0004 0.0011
Schistosoma mansoni inositol monophosphatase 0.0081 0.0256 0.0256
Mycobacterium ulcerans glutaminase 0.0274 0.1025 0.2893
Echinococcus multilocularis dna polymerase eta 0.0141 0.0494 0.0494
Schistosoma mansoni adenoreceptor 0.0047 0.012 0.012
Plasmodium falciparum thioredoxin reductase 0.0018 0.0004 0.0011
Onchocerca volvulus 0.0078 0.0242 0.141
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0447 0.1712 0.7375
Echinococcus granulosus tachykinin peptides receptor 99D 0.0047 0.012 0.012
Brugia malayi Pip kinase protein 2 0.0346 0.131 0.371
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.002 0.0014 0.0014
Toxoplasma gondii Erv1 / Alr family protein 0.0105 0.0351 0.0994
Schistosoma mansoni metabotropic glutamate receptor 0.0028 0.0046 0.0046
Echinococcus multilocularis neuropeptide receptor 0.0047 0.012 0.012
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0105 0.0351 0.0994
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Brugia malayi glutaminase DH11.1 0.0274 0.1025 0.2901
Schistosoma mansoni myosin xvIII 0.0047 0.012 0.012
Toxoplasma gondii ImpB/MucB/SamB family protein 0.0061 0.0176 0.0497
Leishmania major hypothetical protein, conserved 0.0105 0.0351 0.0991
Trypanosoma cruzi pyruvate kinase 2, putative 0.0069 0.0206 0.0583
Echinococcus granulosus metabotropic glutamate receptor 2 0.0042 0.0102 0.0102
Plasmodium falciparum hexokinase 0.0078 0.0242 0.0686
Echinococcus multilocularis thyroid hormone receptor alpha 0.0021 0.0017 0.0017
Brugia malayi MH2 domain containing protein 0.0025 0.0031 0.0089
Trichomonas vaginalis phosphatidylinositol-4-phosphate 5-kinase type II, putative 0.0028 0.0044 0.0296
Echinococcus multilocularis musashi 0.0054 0.0149 0.0149
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0014 0.0014
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0078 0.0244 0.0686
Plasmodium vivax hexokinase, putative 0.0078 0.0242 0.0686
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0034 0.007 0.007
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0069 0.0208 0.0588
Schistosoma mansoni voltage-gated potassium channel 0.002 0.0014 0.0014
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0078 0.0244 0.0686
Toxoplasma gondii hypothetical protein 0.0097 0.0318 0.0901
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0021 0.0017 0.0048
Loa Loa (eye worm) hypothetical protein 0.0306 0.1149 0.4951
Loa Loa (eye worm) hexokinase 0.0078 0.0242 0.1045
Onchocerca volvulus Hexokinase homolog 0.0049 0.0127 0.0741
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0021 0.0017 0.0048
Trichomonas vaginalis conserved hypothetical protein 0.0031 0.0058 0.0402
Brugia malayi nuclear receptor NHR-88 0.0021 0.0017 0.0048
Trichomonas vaginalis CAMK family protein kinase 0.0188 0.0682 0.5008
Plasmodium falciparum cysteine proteinase falcipain 3 0.0018 0.0006 0.0016
Loa Loa (eye worm) hypothetical protein 0.0047 0.012 0.0519
Echinococcus multilocularis lamin 0.0054 0.0149 0.0149
Brugia malayi MH1 domain containing protein 0.0025 0.0031 0.0089
Trichomonas vaginalis chromobox protein, putative 0.0045 0.0114 0.0814

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.