Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Giardia lamblia | NADH oxidase lateral transfer candidate | 0.0087 | 0.098 | 0.2632 |
Mycobacterium tuberculosis | Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate | 0.0023 | 0.0175 | 0.0074 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0087 | 0.098 | 1 |
Echinococcus multilocularis | mixed lineage leukemia protein mll | 0.0015 | 0.0075 | 0.0067 |
Plasmodium vivax | glutathione reductase, putative | 0.0251 | 0.3045 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0087 | 0.098 | 0.1124 |
Trichomonas vaginalis | Citrate lyase beta chain, putative | 0.0072 | 0.0794 | 0.2237 |
Schistosoma mansoni | Tr4/Tr2 (homologue) | 0.001 | 0.0008 | 0.0008 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0087 | 0.098 | 0.1124 |
Trichomonas vaginalis | glutathione reductase, putative | 0.0087 | 0.098 | 0.2792 |
Brugia malayi | GTP-binding regulatory protein Gs alpha-S chain, putative | 0.0044 | 0.0441 | 0.1282 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0023 | 0.0175 | 0.0168 |
Plasmodium falciparum | thioredoxin reductase | 0.0251 | 0.3045 | 1 |
Mycobacterium ulcerans | thioredoxin reductase TrxB2 | 0.0023 | 0.0175 | 0.0667 |
Schistosoma mansoni | hypothetical protein | 0.0803 | 1 | 1 |
Mycobacterium ulcerans | ferredoxin reductase | 0.0023 | 0.0175 | 0.0667 |
Wolbachia endosymbiont of Brugia malayi | NADPH-dependent glutamate synthase beta chain | 0.0023 | 0.0175 | 0.0667 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh | 0.0023 | 0.0175 | 0.0667 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0264 | 0.0264 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0278 | 0.3392 | 0.4271 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0441 | 0.0434 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0023 | 0.0175 | 0.0388 |
Brugia malayi | CXXC zinc finger family protein | 0.0056 | 0.0595 | 0.1735 |
Loa Loa (eye worm) | PLK/PLK1 protein kinase | 0.0278 | 0.3392 | 1 |
Toxoplasma gondii | histone lysine methyltransferase SET/SUV39 | 0.003 | 0.0264 | 0.0498 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0023 | 0.0175 | 0.0388 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0023 | 0.0175 | 0.0075 |
Echinococcus granulosus | NADPH:adrenodoxin oxidoreductase | 0.0023 | 0.0175 | 0.0168 |
Loa Loa (eye worm) | hypothetical protein | 0.003 | 0.0264 | 0.0756 |
Echinococcus multilocularis | citrate lyase subunit beta protein | 0.0072 | 0.0794 | 0.0787 |
Echinococcus multilocularis | NADPH:adrenodoxin oxidoreductase | 0.0023 | 0.0175 | 0.0168 |
Schistosoma mansoni | RAR-like nuclear receptor | 0.001 | 0.0008 | 0.0008 |
Plasmodium vivax | SET domain protein, putative | 0.003 | 0.0264 | 0.0498 |
Echinococcus multilocularis | histone lysine N methyltransferase SETMAR | 0.003 | 0.0264 | 0.0256 |
Entamoeba histolytica | thioredoxin reductase, putative | 0.0023 | 0.0175 | 0.0176 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0023 | 0.0175 | 0.0196 |
Schistosoma mansoni | FTZ-F1 nuclear receptor-like protein | 0.001 | 0.0008 | 0.0008 |
Toxoplasma gondii | thioredoxin reductase | 0.0251 | 0.3045 | 1 |
Leishmania major | 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein | 0.0087 | 0.098 | 0.1124 |
Mycobacterium ulcerans | monoxygenase | 0.0023 | 0.0175 | 0.0667 |
Loa Loa (eye worm) | programmed cell death 8 | 0.0023 | 0.0175 | 0.0495 |
Echinococcus granulosus | thioredoxin glutathione reductase | 0.0252 | 0.3064 | 0.3058 |
Schistosoma mansoni | nuclear hormone receptor | 0.001 | 0.0008 | 0.0008 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase-like protein, putative | 0.0023 | 0.0175 | 0.0075 |
Schistosoma mansoni | kinase | 0.0141 | 0.1667 | 0.1667 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0008 | 0.0008 |
Mycobacterium ulcerans | NADH dehydrogenase | 0.0023 | 0.0175 | 0.0667 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0627 | 0.7784 | 1 |
Echinococcus granulosus | guanine nucleotide binding protein Gs subunit | 0.0044 | 0.0441 | 0.0434 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0023 | 0.0175 | 0.0388 |
Trypanosoma brucei | dihydrolipoyl dehydrogenase | 0.0087 | 0.098 | 0.1124 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0087 | 0.098 | 0.1124 |
Echinococcus granulosus | citrate lyase subunit beta protein | 0.0072 | 0.0794 | 0.0787 |
Schistosoma mansoni | photoreceptor-specific nuclear receptor related | 0.001 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | Conserved protein | 0.0072 | 0.0794 | 0.0869 |
Wolbachia endosymbiont of Brugia malayi | dihydrolipoamide dehydrogenase E3 component | 0.0087 | 0.098 | 1 |
Mycobacterium tuberculosis | Probable NADH dehydrogenase Ndh | 0.0572 | 0.7094 | 0.8966 |
Loa Loa (eye worm) | histone methyltransferase | 0.0019 | 0.0118 | 0.0325 |
Trichomonas vaginalis | dihydrolipoamide dehydrogenase, putative | 0.0023 | 0.0175 | 0.0388 |
Schistosoma mansoni | retinoid-x-receptor (RXR) | 0.001 | 0.0008 | 0.0008 |
Brugia malayi | serine/threonine-protein kinase plk-2 | 0.0278 | 0.3392 | 1 |
Treponema pallidum | oxidoreductase | 0.0023 | 0.0175 | 0.0667 |
Loa Loa (eye worm) | exodeoxyribonuclease III family protein | 0.0019 | 0.0118 | 0.0326 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0087 | 0.098 | 0.1124 |
Mycobacterium leprae | PROBABLE NADH DEHYDROGENASE NDH | 0.0572 | 0.7094 | 0.8958 |
Schistosoma mansoni | steroid hormone receptor ad4bp | 0.001 | 0.0008 | 0.0008 |
Mycobacterium tuberculosis | Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB | 0.0572 | 0.7094 | 0.8966 |
Mycobacterium tuberculosis | Probable membrane NADH dehydrogenase NdhA | 0.0572 | 0.7094 | 0.8966 |
Mycobacterium ulcerans | flavoprotein disulfide reductase | 0.0087 | 0.098 | 1 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0441 | 0.0434 |
Leishmania major | hypothetical protein, conserved | 0.0023 | 0.0175 | 0.0075 |
Mycobacterium tuberculosis | Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot | 0.0087 | 0.098 | 0.1108 |
Entamoeba histolytica | serine/threonine protein kinase, putative | 0.0278 | 0.3392 | 1 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0087 | 0.098 | 0.1124 |
Mycobacterium tuberculosis | Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras | 0.0636 | 0.7898 | 1 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0627 | 0.7784 | 1 |
Mycobacterium tuberculosis | NADPH-dependent mycothiol reductase Mtr | 0.0251 | 0.3045 | 0.3762 |
Trichomonas vaginalis | set domain proteins, putative | 0.023 | 0.2783 | 0.8181 |
Schistosoma mansoni | cpg binding protein | 0.006 | 0.0635 | 0.0635 |
Mycobacterium tuberculosis | NAD(P)H quinone reductase LpdA | 0.0636 | 0.7898 | 1 |
Plasmodium vivax | ferrodoxin reductase, putative | 0.0023 | 0.0175 | 0.0196 |
Mycobacterium tuberculosis | Probable reductase | 0.0572 | 0.7094 | 0.8966 |
Brugia malayi | glutamate synthase | 0.0023 | 0.0175 | 0.0495 |
Toxoplasma gondii | selenide, water dikinase | 0.0023 | 0.0175 | 0.0196 |
Echinococcus granulosus | glutamate synthase | 0.0023 | 0.0175 | 0.0168 |
Onchocerca volvulus | 0.0023 | 0.0175 | 0.0495 | |
Plasmodium vivax | thioredoxin reductase, putative | 0.0251 | 0.3045 | 1 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0023 | 0.0175 | 0.0388 |
Toxoplasma gondii | NADPH-glutathione reductase | 0.0087 | 0.098 | 0.2945 |
Schistosoma mansoni | disulfide oxidoreductase | 0.0023 | 0.0175 | 0.0175 |
Treponema pallidum | NADH oxidase | 0.0087 | 0.098 | 1 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase, point mutation | 0.0087 | 0.098 | 0.1124 |
Entamoeba histolytica | dihydropyrimidine dehydrogenase, putative | 0.0023 | 0.0175 | 0.0176 |
Leishmania major | trypanothione reductase | 0.0251 | 0.3045 | 0.3818 |
Brugia malayi | alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase | 0.0064 | 0.0689 | 0.2014 |
Trypanosoma cruzi | polo-like protein kinase, putative | 0.0278 | 0.3392 | 0.4271 |
Loa Loa (eye worm) | glutathione reductase | 0.0251 | 0.3045 | 0.8974 |
Giardia lamblia | Glycerol-3-phosphate dehydrogenase | 0.0023 | 0.0175 | 0.0176 |
Plasmodium falciparum | ferrodoxin reductase-like protein | 0.0023 | 0.0175 | 0.0196 |
Brugia malayi | dihydrolipoyl dehydrogenase, mitochondrial precursor, putative | 0.0087 | 0.098 | 0.2872 |
Leishmania major | acetoin dehydrogenase e3 component-like protein | 0.0087 | 0.098 | 0.1124 |
Leishmania major | dihydrolipoamide dehydrogenase, putative | 0.0087 | 0.098 | 0.1124 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0019 | 0.0118 | 0.011 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0118 | 0.0216 |
Leishmania major | hypothetical protein, conserved | 0.0023 | 0.0175 | 0.0075 |
Mycobacterium ulcerans | dehydrogenase | 0.0023 | 0.0175 | 0.0667 |
Mycobacterium tuberculosis | Probable dehydrogenase | 0.0572 | 0.7094 | 0.8966 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, mitochondrial, putative | 0.0087 | 0.098 | 0.2945 |
Trichomonas vaginalis | glutamate synthase, putative | 0.0023 | 0.0175 | 0.0388 |
Mycobacterium ulcerans | citrate lyase beta subunit, CitE_2 | 0.0072 | 0.0794 | 0.7848 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0278 | 0.3392 | 1 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0264 | 0.0264 |
Echinococcus multilocularis | pyridine nucleotide disulfide oxidoreductase | 0.0023 | 0.0175 | 0.0168 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase, LpdB | 0.0087 | 0.098 | 1 |
Treponema pallidum | thioredoxin reductase (trxB) | 0.0023 | 0.0175 | 0.0667 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0072 | 0.0794 | 0.0882 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0023 | 0.0175 | 0.0388 |
Mycobacterium ulcerans | hypothetical protein | 0.0023 | 0.0175 | 0.0667 |
Leishmania major | hypothetical protein, conserved | 0.0627 | 0.7784 | 1 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0627 | 0.7784 | 1 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0023 | 0.0175 | 0.0388 |
Schistosoma mansoni | histone-lysine n-methyltransferase suv9 | 0.003 | 0.0264 | 0.0264 |
Trypanosoma brucei | hypothetical protein, conserved | 0.0023 | 0.0175 | 0.0075 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0278 | 0.3392 | 1 |
Echinococcus granulosus | serine:threonine protein kinase PLK1 | 0.0278 | 0.3392 | 0.3387 |
Plasmodium falciparum | thioredoxin reductase | 0.0087 | 0.098 | 0.2945 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0023 | 0.0175 | 0.0196 |
Echinococcus multilocularis | sulfide:quinone oxidoreductase | 0.0023 | 0.0175 | 0.0168 |
Echinococcus granulosus | DNA apurinic or apyrimidinic site lyase | 0.0019 | 0.0118 | 0.011 |
Leishmania major | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0072 | 0.0794 | 0.0882 |
Schistosoma mansoni | sulfide quinone reductase | 0.0023 | 0.0175 | 0.0175 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0087 | 0.098 | 0.1124 |
Entamoeba histolytica | pyridine nucleotide-disulfide oxidoreductase family protein | 0.0023 | 0.0175 | 0.0176 |
Brugia malayi | Thioredoxin reductase | 0.0251 | 0.3045 | 0.8974 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0278 | 0.3392 | 1 |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0015 | 0.0075 | 0.0067 |
Echinococcus granulosus | apoptosis inducing factor 1 mitochondrial | 0.0023 | 0.0175 | 0.0168 |
Onchocerca volvulus | 0.003 | 0.0264 | 0.0756 | |
Giardia lamblia | Kinase, PLK | 0.0278 | 0.3392 | 1 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0118 | 0.0118 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0023 | 0.0175 | 0.0075 |
Plasmodium falciparum | glutathione reductase | 0.0251 | 0.3045 | 1 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0072 | 0.0794 | 0.7848 |
Schistosoma mansoni | sulfide quinone reductase | 0.0023 | 0.0175 | 0.0175 |
Schistosoma mansoni | thyroid hormone receptor | 0.001 | 0.0008 | 0.0008 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0023 | 0.0175 | 0.0075 |
Mycobacterium ulcerans | citrate (pro-3S)-lyase subunit beta | 0.0072 | 0.0794 | 0.7848 |
Toxoplasma gondii | pyruvate dehydrogenase complex subunit PDH-E3II | 0.0087 | 0.098 | 0.2945 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, apicoplast | 0.0087 | 0.098 | 0.2945 |
Echinococcus multilocularis | apoptosis inducing factor 1 mitochondrial | 0.0023 | 0.0175 | 0.0168 |
Echinococcus granulosus | dihydropyrimidine dehydrogenase NADP | 0.0023 | 0.0175 | 0.0168 |
Echinococcus granulosus | histone lysine methyltransferase setb | 0.003 | 0.0264 | 0.0256 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0023 | 0.0175 | 0.0075 |
Echinococcus multilocularis | serine:threonine protein kinase PLK1 | 0.0278 | 0.3392 | 0.3387 |
Toxoplasma gondii | pyridine nucleotide-disulfide oxidoreductase domain-containing protein | 0.0023 | 0.0175 | 0.0196 |
Brugia malayi | glutathione reductase | 0.0251 | 0.3045 | 0.8974 |
Trichomonas vaginalis | ap endonuclease, putative | 0.0019 | 0.0118 | 0.0216 |
Loa Loa (eye worm) | hypothetical protein | 0.0023 | 0.0175 | 0.0495 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0278 | 0.3392 | 1 |
Echinococcus granulosus | 5'partial|histone lysine N methyltransferase SETDB2 | 0.0028 | 0.0235 | 0.0227 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0023 | 0.0175 | 0.0495 |
Wolbachia endosymbiont of Brugia malayi | thioredoxin reductase | 0.0023 | 0.0175 | 0.0667 |
Leishmania major | protein kinase, putative,polo-like protein kinase, putative | 0.0278 | 0.3392 | 0.4271 |
Trypanosoma cruzi | dihydrolipoyl dehydrogenase, putative | 0.0087 | 0.098 | 0.1124 |
Leishmania major | hypothetical protein, conserved | 0.0023 | 0.0175 | 0.0075 |
Trypanosoma cruzi | trypanothione reductase, putative | 0.0251 | 0.3045 | 0.3818 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0138 | 0.1621 | 0.4707 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0121 | 0.1405 | 0.1405 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0087 | 0.098 | 0.1124 |
Mycobacterium ulcerans | NADH dehydrogenase Ndh1 | 0.0023 | 0.0175 | 0.0667 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0441 | 0.0441 |
Schistosoma mansoni | cpg binding protein | 0.006 | 0.0635 | 0.0635 |
Echinococcus multilocularis | histone lysine methyltransferase setb histone lysine methyltransferase eggless | 0.003 | 0.0264 | 0.0256 |
Trypanosoma cruzi | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0023 | 0.0175 | 0.0075 |
Schistosoma mansoni | coup transcription factor | 0.001 | 0.0008 | 0.0008 |
Entamoeba histolytica | disulphide oxidoreductase, putative | 0.0023 | 0.0175 | 0.0176 |
Mycobacterium tuberculosis | Putative ferredoxin reductase | 0.0572 | 0.7094 | 0.8966 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0023 | 0.0175 | 0.0667 |
Trypanosoma cruzi | 2,4-dienoyl-coa reductase fadh1, putative | 0.0023 | 0.0175 | 0.0075 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0087 | 0.098 | 0.1124 |
Mycobacterium tuberculosis | Probable citrate (pro-3S)-lyase (beta subunit) CitE (citrase) (citratase) (citritase) (citridesmolase) (citrase aldolase) | 0.0072 | 0.0794 | 0.0869 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0278 | 0.3392 | 1 |
Loa Loa (eye worm) | pre-SET domain-containing protein family protein | 0.0202 | 0.2433 | 0.7167 |
Plasmodium falciparum | dihydrolipoyl dehydrogenase, mitochondrial | 0.0087 | 0.098 | 0.2945 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0023 | 0.0175 | 0.0388 |
Schistosoma mansoni | hypothetical protein | 0.0023 | 0.0175 | 0.0175 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprB | 0.0023 | 0.0175 | 0.0667 |
Mycobacterium tuberculosis | Possible dehydrogenase/reductase | 0.0023 | 0.0175 | 0.0074 |
Schistosoma mansoni | glutamate synthase | 0.0023 | 0.0175 | 0.0175 |
Mycobacterium ulcerans | glutamate synthase subunit beta | 0.0023 | 0.0175 | 0.0667 |
Trichomonas vaginalis | dihydropyrimidine dehydrogenase, putative | 0.0023 | 0.0175 | 0.0388 |
Echinococcus granulosus | cpg binding protein | 0.006 | 0.0635 | 0.0628 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase family protein | 0.0023 | 0.0175 | 0.0495 |
Wolbachia endosymbiont of Brugia malayi | thioredoxin reductase | 0.0023 | 0.0175 | 0.0667 |
Schistosoma mansoni | histone-lysine n-methyltransferase setb1 | 0.003 | 0.0264 | 0.0264 |
Mycobacterium ulcerans | hypothetical protein | 0.0072 | 0.0794 | 0.7848 |
Toxoplasma gondii | NADH dehydrogenase (NDH2-II) | 0.0023 | 0.0175 | 0.0196 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0087 | 0.098 | 0.1124 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0023 | 0.0175 | 0.0176 |
Brugia malayi | Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein | 0.0064 | 0.0689 | 0.2014 |
Mycobacterium tuberculosis | Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) | 0.0023 | 0.0175 | 0.0074 |
Mycobacterium tuberculosis | NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) | 0.0023 | 0.0175 | 0.0074 |
Echinococcus granulosus | dihydrolipoamide dehydrogenase | 0.0087 | 0.098 | 0.0973 |
Chlamydia trachomatis | dihydrolipoyl dehydrogenase | 0.0087 | 0.098 | 1 |
Trichomonas vaginalis | dihydroorotate dehydrogenase, putative | 0.0023 | 0.0175 | 0.0388 |
Onchocerca volvulus | Serine\/threonine kinase homolog | 0.0278 | 0.3392 | 1 |
Giardia lamblia | Thioredoxin reductase | 0.0023 | 0.0175 | 0.0176 |
Loa Loa (eye worm) | thioredoxin reductase | 0.0251 | 0.3045 | 0.8974 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0441 | 0.0441 |
Echinococcus multilocularis | dnaJ subfamily B | 0.0803 | 1 | 1 |
Schistosoma mansoni | Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) | 0.0044 | 0.0441 | 0.0441 |
Mycobacterium ulcerans | dihydrolipoamide dehydrogenase | 0.0087 | 0.098 | 1 |
Mycobacterium ulcerans | NADPH dependent 2,4-dienoyl-CoA reductase FadH | 0.0023 | 0.0175 | 0.0667 |
Echinococcus multilocularis | cpg binding protein | 0.006 | 0.0635 | 0.0628 |
Loa Loa (eye worm) | CXXC zinc finger family protein | 0.0056 | 0.0595 | 0.1735 |
Entamoeba histolytica | glutamate synthase beta subunit, putative | 0.0023 | 0.0175 | 0.0176 |
Trypanosoma brucei | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0023 | 0.0175 | 0.0075 |
Toxoplasma gondii | non-proton pumping type-II NADH dehydrogenase I | 0.0023 | 0.0175 | 0.0196 |
Toxoplasma gondii | histone lysine methyltransferase SET1 | 0.0108 | 0.1244 | 0.3846 |
Trypanosoma brucei | polo-like protein kinase | 0.0278 | 0.3392 | 0.4271 |
Trichomonas vaginalis | apoptosis inducing factor, putative | 0.0023 | 0.0175 | 0.0388 |
Echinococcus granulosus | mixed lineage leukemia protein mll | 0.0015 | 0.0075 | 0.0067 |
Leishmania major | 2,4-dienoyl-coa reductase-like protein | 0.0023 | 0.0175 | 0.0075 |
Onchocerca volvulus | 0.023 | 0.2783 | 0.8201 | |
Echinococcus multilocularis | histone lysine N methyltransferase MLL3 | 0.0019 | 0.0118 | 0.011 |
Brugia malayi | Pre-SET motif family protein | 0.0202 | 0.2433 | 0.7167 |
Schistosoma mansoni | nuclear hormone receptor nor-1/nor-2 | 0.001 | 0.0008 | 0.0008 |
Schistosoma mansoni | retinoic acid receptor RXR | 0.001 | 0.0008 | 0.0008 |
Echinococcus multilocularis | thioredoxin glutathione reductase | 0.0252 | 0.3064 | 0.3058 |
Trypanosoma cruzi | hypothetical protein, conserved | 0.0023 | 0.0175 | 0.0075 |
Trypanosoma brucei | NADH dehydrogenase | 0.0023 | 0.0175 | 0.0075 |
Trypanosoma brucei | dihydrolipoamide dehydrogenase | 0.0087 | 0.098 | 0.1124 |
Trypanosoma brucei | pyridine nucleotide-disulphide oxidoreductase, putative | 0.0023 | 0.0175 | 0.0075 |
Echinococcus multilocularis | guanine nucleotide binding protein G(s) subunit | 0.0044 | 0.0441 | 0.0434 |
Trypanosoma brucei | trypanothione reductase | 0.0251 | 0.3045 | 0.3818 |
Mycobacterium ulcerans | NADPH:adrenodoxin oxidoreductase FprA | 0.0023 | 0.0175 | 0.0667 |
Plasmodium falciparum | NAD(P)H-dependent glutamate synthase, putative | 0.0023 | 0.0175 | 0.0196 |
Echinococcus granulosus | sulfide:quinone oxidoreductase | 0.0023 | 0.0175 | 0.0168 |
Schistosoma mansoni | ap endonuclease | 0.0019 | 0.0118 | 0.0118 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0023 | 0.0175 | 0.0168 |
Echinococcus multilocularis | dihydrolipoamide dehydrogenase | 0.0087 | 0.098 | 0.0973 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0278 | 0.3392 | 1 |
Echinococcus multilocularis | glutamate synthase | 0.0023 | 0.0175 | 0.0168 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0138 | 0.1621 | 0.4707 |
Plasmodium falciparum | glutathione reductase | 0.0087 | 0.098 | 0.2945 |
Schistosoma mansoni | serine/threonine protein kinase | 0.0278 | 0.3392 | 0.3392 |
Echinococcus multilocularis | dihydropyrimidine dehydrogenase (NADP+) | 0.0023 | 0.0175 | 0.0168 |
Loa Loa (eye worm) | pyridine nucleotide-disufhide oxidoreductase | 0.0023 | 0.0175 | 0.0495 |
Giardia lamblia | Glutamate synthase | 0.0023 | 0.0175 | 0.0176 |
Plasmodium falciparum | type II NADH:ubiquinone oxidoreductase | 0.0023 | 0.0175 | 0.0196 |
Leishmania major | NADH dehydrogenase, putative | 0.0023 | 0.0175 | 0.0075 |
Plasmodium vivax | dihydrolipoyl dehydrogenase, apicoplast, putative | 0.0087 | 0.098 | 0.2945 |
Plasmodium vivax | NAD(P)H-dependent glutamate synthase, putative | 0.0023 | 0.0175 | 0.0196 |
Leishmania major | 2,4-dienoyl-coa reductase fadh1, putative | 0.0023 | 0.0175 | 0.0075 |
Schistosoma mansoni | dihydrolipoamide dehydrogenase | 0.0087 | 0.098 | 0.098 |
Entamoeba histolytica | NAD(FAD)-dependent dehydrogenase, putative | 0.0023 | 0.0175 | 0.0176 |
Brugia malayi | F/Y-rich N-terminus family protein | 0.0018 | 0.0115 | 0.0317 |
Mycobacterium tuberculosis | Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) | 0.0023 | 0.0175 | 0.0074 |
Trypanosoma cruzi | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase, putative | 0.0072 | 0.0794 | 0.0882 |
Loa Loa (eye worm) | GTP-binding regulatory protein Gs alpha-S chain | 0.0044 | 0.0441 | 0.1282 |
Schistosoma mansoni | mixed-lineage leukemia protein mll | 0.0015 | 0.0075 | 0.0075 |
Brugia malayi | exodeoxyribonuclease III family protein | 0.0019 | 0.0118 | 0.0326 |
Trypanosoma cruzi | dihydrolipoamide dehydrogenase, putative | 0.0087 | 0.098 | 0.1124 |
Plasmodium vivax | type II NADH:ubiquinone oxidoreductase, putative | 0.0023 | 0.0175 | 0.0196 |
Mycobacterium leprae | DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE | 0.0636 | 0.7898 | 1 |
Mycobacterium tuberculosis | Probable oxidoreductase | 0.0636 | 0.7898 | 1 |
Trypanosoma cruzi | NADH dehydrogenase, putative | 0.0023 | 0.0175 | 0.0075 |
Brugia malayi | NADPH:adrenodoxin oxidoreductase, mitochondrial precursor | 0.0023 | 0.0175 | 0.0495 |
Schistosoma mansoni | glutamate synthase | 0.0023 | 0.0175 | 0.0175 |
Trypanosoma brucei | 2,4-dienoyl-coa reductase-like protein | 0.0023 | 0.0175 | 0.0075 |
Schistosoma mansoni | glutamate synthase | 0.0023 | 0.0175 | 0.0175 |
Mycobacterium tuberculosis | Probable thioredoxin reductase TrxB2 (TRXR) (TR) | 0.0023 | 0.0175 | 0.0074 |
Mycobacterium ulcerans | hypothetical protein | 0.0072 | 0.0794 | 0.7848 |
Trichomonas vaginalis | mercuric reductase, putative | 0.0087 | 0.098 | 0.2792 |
Trichomonas vaginalis | disulfide oxidoreductase, putative | 0.0023 | 0.0175 | 0.0388 |
Echinococcus multilocularis | DNA (apurinic or apyrimidinic site) lyase | 0.0019 | 0.0118 | 0.011 |
Brugia malayi | Pre-SET motif family protein | 0.003 | 0.0264 | 0.0756 |
Echinococcus granulosus | histone lysine N methyltransferase MLL3 | 0.0015 | 0.0075 | 0.0067 |
Trichomonas vaginalis | CAMK family protein kinase | 0.0278 | 0.3392 | 1 |
Trypanosoma cruzi | NADPH:adrenodoxin oxidoreductase, mitochondrial, putative | 0.0023 | 0.0175 | 0.0075 |
Onchocerca volvulus | 0.0056 | 0.0595 | 0.1735 | |
Schistosoma mansoni | nuclear receptor 2DBD-gamma | 0.001 | 0.0008 | 0.0008 |
Schistosoma mansoni | cpg binding protein | 0.0056 | 0.0595 | 0.0595 |
Echinococcus granulosus | pyridine nucleotide disulfide oxidoreductase | 0.0023 | 0.0175 | 0.0168 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.