Detailed information for compound 801493

Basic information

Technical information
  • TDR Targets ID: 801493
  • Name: ethyl 4-(4-methylphenyl)-2-oxo-6-(piperidin-1 -ylmethyl)-3,4-dihydro-1H-pyrimidine-5-carbox ylate
  • MW: 357.447 | Formula: C20H27N3O3
  • H donors: 2 H acceptors: 2 LogP: 2.06 Rotable bonds: 6
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)C1=C(CN2CCCCC2)NC(=O)NC1c1ccc(cc1)C
  • InChi: 1S/C20H27N3O3/c1-3-26-19(24)17-16(13-23-11-5-4-6-12-23)21-20(25)22-18(17)15-9-7-14(2)8-10-15/h7-10,18H,3-6,11-13H2,1-2H3,(H2,21,22,25)
  • InChiKey: PFEOCHOIHPPWLH-UHFFFAOYSA-N  


Substructure search Similarity search

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Synonyms

  • ethyl 4-(4-methylphenyl)-2-oxo-6-(1-piperidylmethyl)-3,4-dihydro-1H-pyrimidine-5-carboxylate
  • 4-(4-methylphenyl)-2-oxo-6-(1-piperidylmethyl)-3,4-dihydro-1H-pyrimidine-5-carboxylic acid ethyl ester
  • 2-keto-4-(4-methylphenyl)-6-(piperidinomethyl)-3,4-dihydro-1H-pyrimidine-5-carboxylic acid ethyl ester
  • C430-0796
  • NCGC00108439-01

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.004 0.0042
Echinococcus multilocularis nuclear factor of activated T cells 5 0.005 0.0209 0.0209
Giardia lamblia Kinase, PLK 0.1644 0.9398 1
Mycobacterium leprae DIHYDROLIPOAMIDE DEHYDROGENASE LPD (LIPOAMIDE REDUCTASE (NADH)) (LIPOYL DEHYDROGENASE) (DIHYDROLIPOYL DEHYDROGENASE) (DIAPHORASE 0.0476 0.2666 1
Mycobacterium leprae POSSIBLE FATTY-ACID-CoA LIGASE FADD10 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0021 0.004 0.0077
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0019 0.0019
Echinococcus granulosus sodium coupled monocarboxylate transporter 1 0.0077 0.0367 0.039
Echinococcus multilocularis endonuclease exonuclease phosphatase 0.0016 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.004 0.015 0.0149
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0019
Toxoplasma gondii propionate-CoA ligase 0.0021 0.004 0.0198
Brugia malayi Amiloride-sensitive sodium channel family protein 0.0134 0.0692 0.0736
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Echinococcus multilocularis CCR4 NOT transcription complex subunit 6 0.0016 0.0012 0.0012
Brugia malayi orphan nuclear receptor NR2E1 0.0064 0.029 0.0308
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0114 0.012
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0125 0.0122
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.019 0.0192
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0016 0.0012 0.0012
Echinococcus granulosus tar DNA binding protein 0.0583 0.3282 0.3492
Brugia malayi Probable G protein-coupled receptor kinase F19C6.1, putative 0.0082 0.0392 0.0418
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0042 0.0161 0.0846
Echinococcus granulosus neuropeptide receptor 0.0017 0.0019 0.002
Mycobacterium tuberculosis Probable endonuclease IV End (endodeoxyribonuclease IV) (apurinase) 0.0095 0.0467 0.1716
Echinococcus multilocularis sulfide:quinone oxidoreductase 0.0017 0.002 0.002
Plasmodium vivax acyl-CoA synthetase, putative 0.0053 0.0225 0.2168
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.002
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0065 0.0296 0.0314
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0019 0.0019
Plasmodium falciparum dihydrolipoyl dehydrogenase, mitochondrial 0.0065 0.0296 0.2924
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Echinococcus multilocularis pyruvate kinase 0.0017 0.0017 0.0017
Brugia malayi nuclear receptor NHR-67 0.0064 0.029 0.0308
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0012 0.0047
Schistosoma mansoni jumonji/arid domain-containing protein 0.0142 0.074 0.0788
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0017 0.0017 0.0018
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0142 0.0151
Onchocerca volvulus 0.0062 0.0277 0.0295
Toxoplasma gondii LsmAD domain-containing protein 0.0053 0.0225 0.1186
Loa Loa (eye worm) hypothetical protein 0.0064 0.029 0.0308
Schistosoma mansoni amine GPCR 0.0017 0.0019 0.002
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.0035 0.0125 0.0133
Brugia malayi Glycosyl hydrolases family 31 protein 0.016 0.0842 0.0895
Echinococcus granulosus inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0012 0.0013
Echinococcus multilocularis cathepsin L cysteine protease 0.003 0.0094 0.0094
Loa Loa (eye worm) hypothetical protein 0.0111 0.0561 0.0597
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0019
Echinococcus multilocularis expressed protein 0.149 0.8512 0.8512
Onchocerca volvulus 0.0072 0.0334 0.0356
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0065 0.0296 0.7795
Brugia malayi A-kinase anchor protein 10, precursor 0.0077 0.0362 0.0385
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0329 0.0349
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0072 0.0334 0.0356
Schistosoma mansoni hypothetical protein 0.0039 0.0144 0.0153
Schistosoma mansoni FMRFamide-gated Na+ channel 0.0134 0.0692 0.0736
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0329 0.0349
Echinococcus granulosus cathepsin L 0.0016 0.001 0.0011
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0019 0.002
Trypanosoma cruzi cruzipain precursor, putative 0.0115 0.0584 0.062
Toxoplasma gondii aldehyde dehydrogenase 0.019 0.1018 0.5425
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0012 0.0012
Trypanosoma brucei NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0017 0.002 0.0011
Brugia malayi GH02984p 0.0702 0.3966 0.422
Trypanosoma cruzi cytochrome P450, putative 0.0018 0.0026 0.0026
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0079 0.0374 0.0397
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.002 0.002
Echinococcus granulosus histone acetyltransferase KAT2B 0.0044 0.0172 0.0183
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0072 0.0334 0.0356
Schistosoma mansoni alpha-glucosidase 0.0138 0.0713 0.0759
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0749 0.0749
Loa Loa (eye worm) hypothetical protein 0.0072 0.0334 0.0356
Trypanosoma brucei JmjC domain, hydroxylase, putative 0.0035 0.0124 0.0121
Schistosoma mansoni acid sensing ion channel 4 pituitary 0.0134 0.0692 0.0736
Onchocerca volvulus 0.0016 0.0013 0.0014
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0017 0.002 0.0011
Schistosoma mansoni neuropeptide receptor 0.0017 0.0019 0.002
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0043 0.0167 0.0936
Trypanosoma brucei ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0113 0.011
Loa Loa (eye worm) PHD-finger family protein 0.0062 0.0275 0.0293
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0019 0.002
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0069 0.0074
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0017 0.002 0.009
Onchocerca volvulus 0.0064 0.029 0.0308
Mycobacterium tuberculosis Phenyloxazoline synthase MbtB (phenyloxazoline synthetase) 0.0021 0.004 0.0107
Loa Loa (eye worm) hypothetical protein 0.0134 0.0692 0.0736
Echinococcus multilocularis Jumonji, AT rich interactive domain 1B 0.0045 0.0181 0.0181
Echinococcus granulosus nuclear factor of activated T cells 5 0.005 0.0209 0.0223
Echinococcus multilocularis axis inhibition protein axin 0.0077 0.0362 0.0362
Plasmodium falciparum cysteine proteinase falcipain 3 0.003 0.0094 0.0913
Loa Loa (eye worm) hypothetical protein 0.002 0.0037 0.0039
Brugia malayi hypothetical protein 0.0077 0.0362 0.0385
Echinococcus granulosus geminin 0.1019 0.5797 0.6168
Loa Loa (eye worm) nuclear receptor nhr-7B 0.0064 0.029 0.0308
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0019
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0012 0.0002
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0019 0.0019
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0012 0.0013
Echinococcus multilocularis G protein coupled receptor 139 0.0017 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.0017 0.0018 0.0019
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0071 0.0327 0.0327
Echinococcus granulosus thyroid hormone receptor alpha 0.0064 0.029 0.0308
Trichomonas vaginalis glutamate synthase, putative 0.0017 0.002 0.0011
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0136 0.0704 0.0749
Brugia malayi RE15519p 0.0017 0.0019 0.002
Mycobacterium tuberculosis Putative ferredoxin reductase 0.0428 0.239 0.8962
Trypanosoma brucei apurinic/apyrimidinic endonuclease, putative 0.0079 0.0374 0.0387
Echinococcus multilocularis cpg binding protein 0.0186 0.0992 0.0992
Echinococcus multilocularis regulator of G protein signaling 3 0.0077 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0385
Entamoeba histolytica pyridine nucleotide-disulfide oxidoreductase family protein 0.0017 0.002 0.0011
Entamoeba histolytica NAD(FAD)-dependent dehydrogenase, putative 0.0017 0.002 0.0011
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0129
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0017 0.0019 0.0019
Echinococcus granulosus pyruvate kinase 0.0033 0.0109 0.0116
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.003 0.0094 0.0101
Loa Loa (eye worm) hypoxia-induced factor 1 0.0102 0.0511 0.0544
Leishmania major hypothetical protein, conserved 0.0017 0.002 0.002
Schistosoma mansoni transcription factor LCR-F1 0.0039 0.0143 0.0152
Schistosoma mansoni hypothetical protein 0.1019 0.5797 0.6168
Chlamydia trachomatis pyruvate kinase 0.0033 0.0109 0.199
Echinococcus granulosus cpg binding protein 0.0186 0.0992 0.1055
Brugia malayi nuclear receptor RXR 0.0064 0.029 0.0308
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0057 0.0247 0.0263
Brugia malayi hypothetical protein 0.0017 0.0019 0.002
Onchocerca volvulus 0.0017 0.0019 0.002
Echinococcus granulosus Na channel amiloride sensitive 0.0134 0.0692 0.0736
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.0018 0.0018
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0019 0.002
Echinococcus granulosus FMRFamide activated amiloride sensitive sodium 0.0134 0.0692 0.0736
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Trichomonas vaginalis CAMK family protein kinase 0.0814 0.4612 0.4902
Loa Loa (eye worm) thioredoxin reductase 0.0188 0.1003 0.1067
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0017 0.002 0.0011
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0012 0.0012
Echinococcus multilocularis aldehyde dehydrogenase, mitochondrial 0.019 0.1018 0.1018
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0136 0.0704 0.0704
Trypanosoma cruzi endonuclease/exonuclease/phosphatase, putative 0.0016 0.0012 0.0012
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0012 0.0013
Schistosoma mansoni hypothetical protein 0.0134 0.0692 0.0736
Brugia malayi sulfakinin receptor protein 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Trichomonas vaginalis conserved hypothetical protein 0.004 0.015 0.0149
Echinococcus granulosus ATP dependent DNA helicase Q1 0.0026 0.0069 0.0074
Echinococcus granulosus apoptosis inducing factor 1 mitochondrial 0.0017 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0064 0.029 0.0308
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0109 0.0116
Echinococcus multilocularis A kinase anchor protein 10, mitochondrial 0.0077 0.0362 0.0362
Trypanosoma cruzi apurinic/apyrimidinic endonuclease, putative 0.0016 0.0012 0.0012
Mycobacterium tuberculosis Conserved hypothetical protein 0.0025 0.0064 0.0197
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0362 0.0374
Schistosoma mansoni neuropeptide receptor 0.0017 0.0019 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0136 0.0704 0.0749
Brugia malayi hypothetical protein 0.0039 0.0144 0.0153
Schistosoma mansoni cathepsin F (C01 family) 0.003 0.0094 0.0101
Echinococcus multilocularis potassium voltage gated channel subfamily H 0.0022 0.0048 0.0048
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.0064 0.029 0.0308
Schistosoma mansoni amine GPCR 0.0017 0.0019 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0115 0.0584 0.0611
Trichomonas vaginalis type IV inositol 5-phosphatase, putative 0.0016 0.0012 0.0002
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0073 0.0067
Brugia malayi PXA domain containing protein 0.0077 0.0362 0.0385
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0017 0.002 0.0011
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0136 0.0704 0.0749
Echinococcus granulosus nuclear receptor nhr 48 0.0064 0.029 0.0308
Loa Loa (eye worm) hypothetical protein 0.0136 0.0704 0.0749
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0037 0.0029
Echinococcus granulosus pyruvate kinase 0.0033 0.0109 0.0116
Echinococcus granulosus sodium:glucose cotransporter 2 0.0077 0.0367 0.039
Entamoeba histolytica hypothetical protein 0.0039 0.0143 0.0141
Schistosoma mansoni myst-related protein 0.0021 0.004 0.0043
Brugia malayi regulator of G-protein signaling rgs-7 0.0077 0.0362 0.0385
Leishmania major 3-oxoacyl-(acyl-carrier protein) reductase, putative 0.0043 0.0167 0.0177
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0016 0.001 0.0011
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0019 0.0019
Onchocerca volvulus Serine\/threonine kinase homolog 0.1644 0.9398 1
Plasmodium falciparum acetyl-CoA synthetase, putative 0.0021 0.004 0.0371
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0012 0.0013
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0142 0.014
Echinococcus granulosus G protein coupled receptor 139 0.0017 0.0019 0.002
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0329 0.035
Toxoplasma gondii histone lysine demethylase JMJC1/KDM5D/JARID1D 0.0035 0.0124 0.0644
Echinococcus multilocularis sodium:glucose cotransporter 2 0.0077 0.0367 0.0367
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0134 0.0692 0.0736
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0142 0.014
Brugia malayi GnHR receptor homolog 0.0017 0.0019 0.002
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0017 0.002 0.0011
Brugia malayi Regulator of G protein signaling domain containing protein 0.0077 0.0362 0.0385
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0019 0.002
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0012 0.0002
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0064 0.029 0.029
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0225 0.0239
Echinococcus granulosus expressed protein 0.149 0.8512 0.9057
Plasmodium falciparum histone acetyltransferase GCN5 0.004 0.0151 0.148
Brugia malayi AMP-binding enzyme family protein 0.0021 0.004 0.0043
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.019 0.0192
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0975 0.1028
Echinococcus multilocularis tissue type plasminogen activator 0.0017 0.0018 0.0018
Loa Loa (eye worm) hypothetical protein 0.0065 0.0294 0.0313
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0429 0.2394 0.2547
Echinococcus granulosus phd:f box containing protein 0.0035 0.0124 0.0132
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD5 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0209 0.0742
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0065 0.0296 0.0304
Echinococcus multilocularis FMRFamide activated amiloride sensitive sodium 0.0134 0.0692 0.0692
Echinococcus granulosus 7tm_1 domain containing protein 0.0017 0.0019 0.002
Trichomonas vaginalis helicase, putative 0.004 0.015 0.0149
Loa Loa (eye worm) hypothetical protein 0.0036 0.0129 0.0137
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0385
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0017 0.002 0.0011
Echinococcus multilocularis acetyl coenzyme A synthetase, cytoplasmic 0.0021 0.004 0.004
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0017 0.0019 0.002
Echinococcus multilocularis regulator of G protein signaling 7 0.0077 0.0362 0.0362
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.012 0.0613 0.0652
Mycobacterium ulcerans long-chain fatty-acid CoA ligase 0.0071 0.0329 0.1959
Leishmania major cathepsin L-like protease 0.003 0.0094 0.01
Trichomonas vaginalis maltase-glucoamylase, putative 0.0035 0.0125 0.0122
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0017 0.002 0.009
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0019 0.0019
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0016 0.0012 0.0087
Loa Loa (eye worm) hypothetical protein 0.0702 0.3966 0.422
Mycobacterium leprae Probable fatty-acid-CoA synthetase FadD22 (fatty-acid-CoA ligase) (fatty-acid-CoA synthase) 0.0021 0.004 0.0077
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0055 0.0237 0.0252
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0115 0.0584 0.0611
Trichomonas vaginalis CAMK family protein kinase 0.1644 0.9398 1
Plasmodium falciparum type II NADH:ubiquinone oxidoreductase 0.0017 0.002 0.0168
Schistosoma mansoni multiple ankyrin repeats single kh domain protein 0.0055 0.0237 0.0252
Mycobacterium tuberculosis Bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ArCP synthetase 0.0021 0.004 0.0107
Echinococcus multilocularis regulator of G protein signaling 3 0.0077 0.0362 0.0362
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0012 0.0012
Echinococcus multilocularis amiloride sensitive cation channel 4 A 0.0134 0.0692 0.0692
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0019 0.0019
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0136 0.0704 0.0749
Loa Loa (eye worm) acetyltransferase 0.0148 0.0776 0.0826
Echinococcus granulosus amiloride sensitive cation channel 0.0134 0.0692 0.0736
Schistosoma mansoni amiloride-sensitive sodium channel-related 0.0134 0.0692 0.0736
Echinococcus multilocularis pyridine nucleotide disulfide oxidoreductase 0.0017 0.002 0.002
Trypanosoma cruzi RNA-editing complex protein MP100, putative 0.0016 0.0012 0.0012
Echinococcus multilocularis microtubule associated protein 2 0.1383 0.7898 0.7898
Echinococcus multilocularis hyperpolarization activated cyclic 0.0016 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0071 0.0329 0.035
Giardia lamblia Endonuclease/Exonuclease/phosphatase 0.0079 0.0374 0.0385
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0017 0.0019 0.002
Echinococcus granulosus g protein coupled receptor 0.0017 0.0019 0.002
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0017 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0043
Schistosoma mansoni loxhd1 0.0039 0.0144 0.0153
Brugia malayi ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0069 0.0074
Echinococcus multilocularis neutral sphingomyelinase 0.0016 0.0012 0.0012
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0017 0.0019 0.002
Echinococcus multilocularis glutamate synthase 0.0017 0.002 0.002
Trichomonas vaginalis sucrase-isomaltase, putative 0.0035 0.0125 0.0122
Brugia malayi Flap endonuclease-1 0.0018 0.0023 0.0024
Schistosoma mansoni hypothetical protein 0.0016 0.0012 0.0013
Trypanosoma cruzi hypothetical protein, conserved 0.0017 0.002 0.002
Trypanosoma cruzi ISWI complex protein 0.0018 0.0027 0.0028
Plasmodium falciparum glutathione reductase 0.0065 0.0296 0.2924
Loa Loa (eye worm) hypothetical protein 0.0053 0.0225 0.024
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0921 0.0971
Echinococcus multilocularis deoxyribonuclease 1 2 0.0016 0.0012 0.0012
Mycobacterium ulcerans sugar phosphate isomerases/epimerases 0.0025 0.0064 0.0281
Echinococcus granulosus flap endonuclease 1 0.0018 0.0023 0.0024
Loa Loa (eye worm) cysteine protease 0.003 0.0094 0.0101
Echinococcus multilocularis expressed conserved protein 0.0014 0.0003 0.0003
Brugia malayi hypothetical protein 0.0017 0.0019 0.002
Trichomonas vaginalis hypothetical protein 0.0021 0.0044 0.0036
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0094 0.009
Echinococcus granulosus synaptojanin 1 0.0016 0.0012 0.0013
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0017 0.0018 0.0079
Trichomonas vaginalis set domain proteins, putative 0.0488 0.2733 0.29
Echinococcus granulosus solute carrier family 5 0.0077 0.0367 0.039
Wolbachia endosymbiont of Brugia malayi dihydrolipoamide dehydrogenase E3 component 0.0065 0.0296 0.7795
Trichomonas vaginalis DNA polymerase eta, putative 0.0038 0.0142 0.014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0072 0.0334 0.0356
Schistosoma mansoni single-minded 0.0033 0.0111 0.0118
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0124 0.0132
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0053 0.0225 0.024
Plasmodium vivax type II NADH:ubiquinone oxidoreductase, putative 0.0017 0.002 0.01
Echinococcus granulosus regulator of G protein signaling 7 0.0077 0.0362 0.0385
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0017 0.0019 0.0019
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0017 0.002 0.0011
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0392 0.0418
Echinococcus granulosus Nuclear hormone receptor HR96 0.0064 0.029 0.0308
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0016 0.0012 0.0012
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0012 0.0013
Trichomonas vaginalis apoptosis inducing factor, putative 0.0017 0.002 0.0011
Brugia malayi Amiloride-sensitive sodium channel family protein 0.0134 0.0692 0.0736
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0003 0.0003
Echinococcus multilocularis bloom syndrome protein 0.0063 0.0281 0.0281
Schistosoma mansoni rab geranylgeranyl transferase alpha subunit 0.0038 0.0142 0.0151
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0115 0.0584 0.0611
Onchocerca volvulus 0.0017 0.0019 0.002
Brugia malayi hypothetical protein 0.0017 0.0019 0.002
Echinococcus multilocularis dihydrolipoamide dehydrogenase 0.0065 0.0296 0.0296
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0142 0.014
Echinococcus granulosus DNA apurinic or apyrimidinic site lyase 0.0079 0.0374 0.0397
Onchocerca volvulus 0.0017 0.0019 0.002
Leishmania major DNA polymerase eta, putative 0.0038 0.0142 0.015
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0921 0.0971
Trypanosoma cruzi inositol 5-phosphatase 1, putative 0.0016 0.0012 0.0012
Echinococcus multilocularis neuropeptides capa receptor 0.0017 0.0019 0.0019
Schistosoma mansoni glutamate synthase 0.0017 0.002 0.0021
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0039 0.0143 0.0152
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0066 0.0301 0.032
Mycobacterium tuberculosis Possible DNA-damage-inducible protein P DinP (DNA polymerase V) (pol IV 2) (DNA nucleotidyltransferase (DNA-directed)) 0.0038 0.0142 0.0488
Schistosoma mansoni neuropeptide f receptor 76f 0.0017 0.0019 0.002
Echinococcus multilocularis hyperpolarization activated cyclic 0.0016 0.0012 0.0012
Echinococcus multilocularis Transcription factor, JmjC domain containing protein 0.0259 0.1416 0.1416
Brugia malayi DNA-(Apurinic or apyrimidinic site) lyase 0.0095 0.0467 0.0497
Schistosoma mansoni gcn5proteinral control of amino-acid synthesis 5-like 2 gcnl2 0.0148 0.0776 0.0826
Trypanosoma cruzi cysteine peptidase, putative 0.0115 0.0584 0.062
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0059 0.0259 0.0276
Brugia malayi Cathepsin L-like precursor 0.003 0.0094 0.0101
Echinococcus granulosus amiloride sensitive cation channel 4 A 0.0134 0.0692 0.0736
Echinococcus multilocularis voltage gated potassium channel 0.0022 0.0048 0.0048
Mycobacterium tuberculosis Probable peptide synthetase Nrp (peptide synthase) 0.0021 0.004 0.0107
Brugia malayi Degenerin unc-8 0.0134 0.0692 0.0736
Loa Loa (eye worm) hypothetical protein 0.0136 0.0704 0.0749
Leishmania major protein kinase, putative 0.0023 0.0053 0.0055
Schistosoma mansoni jumonji domain containing protein 0.0218 0.1177 0.1252
Loa Loa (eye worm) fibroinase 0.003 0.0094 0.0101
Echinococcus multilocularis cathepsin L cysteine protease 0.003 0.0094 0.0094
Echinococcus granulosus beta-adrenergic receptor kinase 0.0082 0.0392 0.0418
Echinococcus multilocularis FMRFamide activated amiloride sensitive sodium 0.0134 0.0692 0.0692
Brugia malayi Tachykinin-like peptides receptor 99D 0.0017 0.0019 0.002
Schistosoma mansoni adenoreceptor 0.0017 0.0019 0.002
Plasmodium falciparum LCCL domain-containing protein 0.0039 0.0144 0.1408
Onchocerca volvulus 0.0017 0.0019 0.002
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0019
Brugia malayi alpha keto acid dehydrogenase complex, E3 component, lipoamide dehydrogenase 0.0048 0.0196 0.0209
Plasmodium vivax histone acetyltransferase GCN5, putative 0.0044 0.0172 0.1632
Mycobacterium tuberculosis Probable NADPH:adrenodoxin oxidoreductase FprB (adrenodoxin reductase) (AR) (ferredoxin-NADP(+) reductase) 0.0017 0.002 0.0031
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.0064 0.029 0.0308
Loa Loa (eye worm) amiloride-sensitive sodium channel family protein 0.0134 0.0692 0.0736
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0012 0.0013
Treponema pallidum NADH oxidase 0.0065 0.0296 0.7844
Plasmodium falciparum ferrodoxin reductase-like protein 0.0017 0.002 0.0168
Echinococcus granulosus g protein coupled receptor 0.0017 0.0019 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.002
Mycobacterium ulcerans O-succinylbenzoic acid--CoA ligase 0.0021 0.004 0.0129
Trypanosoma cruzi Present in the outer mitochondrial membrane proteome 4 0.0034 0.0114 0.012
Plasmodium falciparum pyruvate kinase 2 0.0017 0.0017 0.0141
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.004 0.0042
Schistosoma mansoni cpg binding protein 0.0186 0.0992 0.1055
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Mycobacterium tuberculosis Probable oxidoreductase 0.0476 0.2666 1
Trypanosoma brucei ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0114 0.0111
Brugia malayi AF-10 protein 0.002 0.0036 0.0039
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0136 0.0704 0.0749
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0749 0.0797
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0329 0.1959
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0064 0.029 0.0308
Leishmania major hypothetical protein, conserved 0.0035 0.0124 0.0131
Mycobacterium leprae POSSIBLE O-SUCCINYLBENZOIC ACID--CoA LIGASE MENE (OSB-CoA SYNTHETASE) (O-SUCCINYLBENZOATE-CoA SYNTHASE) 0.0021 0.004 0.0077
Schistosoma mansoni kinase 0.0835 0.4737 0.5041
Entamoeba histolytica inositol polyphosphate 5-phosphatase, putative 0.0016 0.0012 0.0002
Onchocerca volvulus 0.0017 0.0019 0.002
Trichomonas vaginalis DNA helicase recq, putative 0.0063 0.0281 0.0289
Brugia malayi Steroid receptor seven-up type 2 0.0136 0.0704 0.0749
Brugia malayi Protein kinase domain containing protein 0.0017 0.0018 0.0019
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0109 0.0116
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0136 0.0704 0.0749
Brugia malayi F/Y-rich N-terminus family protein 0.0076 0.0359 0.0382
Schistosoma mansoni jumonji/arid domain-containing protein 0.0142 0.074 0.0788
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0019 0.002
Echinococcus granulosus FMRFamide activated amiloride sensitive sodium 0.0134 0.0692 0.0736
Onchocerca volvulus 0.0017 0.0019 0.002
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.002
Echinococcus granulosus jumonji domain containing protein 0.0086 0.0414 0.0441
Trichomonas vaginalis mercuric reductase, putative 0.0065 0.0296 0.0304
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0583 0.3282 0.3492
Brugia malayi oxidoreductase, short chain dehydrogenase/reductase family protein 0.0021 0.004 0.0043
Echinococcus granulosus aldehyde dehydrogenase mitochondrial 0.019 0.1018 0.1084
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Onchocerca volvulus Cathepsin L homolog 0.003 0.0094 0.0101
Plasmodium falciparum zinc finger protein, putative 0.0021 0.004 0.0368
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0035 0.0124 0.0131
Toxoplasma gondii Acetyl-coenzyme A synthetase 2, putative 0.0021 0.004 0.0198
Echinococcus granulosus thioredoxin glutathione reductase 0.0188 0.1006 0.1071
Trichomonas vaginalis DNA polymerase IV / kappa, putative 0.0038 0.0142 0.014
Plasmodium falciparum glutathione reductase 0.0188 0.1003 1
Schistosoma mansoni pyruvate kinase 0.0033 0.0109 0.0116
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0017 0.0019 0.002
Schistosoma mansoni tar DNA-binding protein 0.0583 0.3282 0.3492
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0065 0.0294 0.1555
Trypanosoma cruzi JmjC domain, hydroxylase, putative 0.0035 0.0124 0.0131
Brugia malayi hypothetical protein 0.0064 0.029 0.0308
Onchocerca volvulus 0.0017 0.0019 0.002
Schistosoma mansoni nuclear hormone receptor 0.0064 0.029 0.0308
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0115 0.0584 0.0611
Schistosoma mansoni DNA helicase recq5 0.0026 0.0069 0.0074
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0749 0.0797
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.002
Loa Loa (eye worm) nuclear receptor NHR-67 0.0064 0.029 0.0308
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.019 0.0192
Echinococcus multilocularis mixed lineage leukemia protein mll 0.0046 0.0185 0.0185
Trichomonas vaginalis dihydroorotate dehydrogenase, putative 0.0017 0.002 0.0011
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0019 0.002
Onchocerca volvulus 0.0176 0.0934 0.0994
Loa Loa (eye worm) CYP4Cod1 0.0018 0.0026 0.0027
Loa Loa (eye worm) hypothetical protein 0.0064 0.029 0.0308
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0019 0.002
Onchocerca volvulus Alhambra homolog 0.0062 0.0275 0.0293
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0124 0.0132
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0115 0.0584 0.0611
Brugia malayi hypothetical protein 0.0083 0.0398 0.0423
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0136 0.0704 0.0704
Treponema pallidum exodeoxyribonuclease (exoA) 0.0079 0.0374 1
Trichomonas vaginalis glutamate synthase, putative 0.0017 0.002 0.0011
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0094 0.009
Echinococcus granulosus lysine specific demethylase 6a 0.0035 0.0124 0.0132
Entamoeba histolytica dihydropyrimidine dehydrogenase, putative 0.0017 0.002 0.0011
Loa Loa (eye worm) hypothetical protein 0.0108 0.0546 0.0581
Mycobacterium tuberculosis Probable aldehyde dehydrogenase 0.019 0.1018 0.3793
Echinococcus granulosus mixed lineage leukemia protein mll 0.0046 0.0185 0.0197
Loa Loa (eye worm) ATP-dependent DNA helicase 0.0026 0.0069 0.0074
Loa Loa (eye worm) hypothetical protein 0.012 0.0613 0.0652
Echinococcus granulosus g-protein coupled receptor 0.0017 0.0019 0.002
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0136 0.0704 0.0749
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0294 0.0313
Trypanosoma cruzi trypanothione reductase, putative 0.0065 0.0296 0.0314
Schistosoma mansoni SET domain protein 0.0016 0.0013 0.0014
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.0064 0.029 0.0308
Brugia malayi PXA domain containing protein 0.0077 0.0362 0.0385
Giardia lamblia DINP protein human, muc B family 0.0038 0.0142 0.0138
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0012 0.0018
Echinococcus granulosus ecdysone induced protein 78C 0.0136 0.0704 0.0749
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0017 0.0019 0.002
Mycobacterium ulcerans dihydrolipoamide dehydrogenase, LpdB 0.0065 0.0296 0.175
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.002
Echinococcus multilocularis lysine specific demethylase 6a 0.0035 0.0124 0.0124
Schistosoma mansoni jumonji domain containing protein 0.0035 0.0124 0.0132
Brugia malayi Bloom's syndrome protein homolog 0.0063 0.0281 0.0299
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0017 0.0019 0.0019
Leishmania major cathepsin L-like protease 0.003 0.0094 0.01
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0024 0.0057 0.0061
Trypanosoma cruzi trypanothione reductase, putative 0.0188 0.1003 0.1066
Trypanosoma brucei cytochrome P450, putative 0.0018 0.0026 0.0016
Mycobacterium ulcerans long-chain-acyl-CoA synthetase 0.0021 0.004 0.0129
Echinococcus granulosus pyridine nucleotide disulfide oxidoreductase 0.0017 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0013
Onchocerca volvulus 0.0077 0.0367 0.039
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0129
Loa Loa (eye worm) hypothetical protein 0.0053 0.0225 0.024
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0105 0.0526 0.0559
Echinococcus multilocularis inositol polyphosphate 5 phosphatase OCRL 1 0.0016 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0053 0.0225 0.024
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0016 0.0012 0.0012
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0094 0.009
Echinococcus granulosus FMRFamide activated amiloride sensitive sodium 0.0134 0.0692 0.0736
Echinococcus multilocularis neuropeptide receptor 0.0017 0.0019 0.0019
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.002
Echinococcus granulosus neuropeptide Y receptor 0.0017 0.0019 0.002
Schistosoma mansoni cathepsin F (C01 family) 0.002 0.0037 0.0039
Leishmania major protein kinase, putative 0.0014 0.0003 0.0002
Trichomonas vaginalis CAMK family protein kinase 0.1644 0.9398 1
Mycobacterium ulcerans putative regulatory protein 0.0024 0.0062 0.0265
Echinococcus multilocularis Regulator of G protein signaling 20 0.0077 0.0362 0.0362
Plasmodium falciparum phd finger protein, putative 0.0062 0.0275 0.2723
Onchocerca volvulus 0.0064 0.029 0.0308
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0921 0.0971
Wolbachia endosymbiont of Brugia malayi exonuclease III 0.0079 0.0374 1
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0017 0.0019 0.0019
Echinococcus granulosus serotonin receptor 0.0017 0.0019 0.002
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0017 0.0019 0.002
Schistosoma mansoni tar DNA-binding protein 0.0583 0.3282 0.3492
Trypanosoma brucei pyridine nucleotide-disulphide oxidoreductase, putative 0.0017 0.002 0.0011
Schistosoma mansoni sulfide quinone reductase 0.0017 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0134 0.0692 0.0736
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0017 0.0019 0.002
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0136 0.0704 0.0749
Echinococcus granulosus somatostatin receptor 0.0017 0.0019 0.002
Trypanosoma cruzi flap endonuclease-1 (FEN-1), putative 0.0018 0.0023 0.0023
Loa Loa (eye worm) programmed cell death 8 0.0017 0.002 0.0021
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0019 0.0019
Trichomonas vaginalis Phospholipase C precursor, putative 0.0016 0.0012 0.0002
Echinococcus granulosus sodium channel nonvoltage gated 1 alpha 0.0134 0.0692 0.0736
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0017 0.0019 0.002
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0064 0.029 0.0308
Echinococcus granulosus cGMP dependent protein kinase 1 0.0014 0.0003 0.0003
Trypanosoma brucei unspecified product 0.0026 0.0073 0.0067
Onchocerca volvulus Nuclear receptor subfamily 6 group A member 1 homolog 0.0064 0.029 0.0308
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.0026 0.0027
Trypanosoma brucei DNA-(apurinic or apyrimidinic site) lyase, putative 0.0016 0.0012 0.0002
Brugia malayi acetyltransferase, GNAT family protein 0.0148 0.0776 0.0826
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0013
Echinococcus granulosus glutamate synthase 0.0017 0.002 0.0021
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtE 0.0021 0.004 0.0129
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0094 0.009
Echinococcus multilocularis jumonji domain containing 1A 0.0035 0.0124 0.0124
Echinococcus multilocularis nuclear receptor nhr 48 0.0064 0.029 0.029
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0115 0.0584 0.0611
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0019 0.002
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0071 0.0329 0.1959
Loa Loa (eye worm) amiloride-sensitive sodium channel family protein 0.0134 0.0692 0.0736
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0012 0.0047
Entamoeba histolytica exodeoxyribonuclease III, putative 0.0079 0.0374 0.0387
Trypanosoma brucei PAB1-binding protein , putative 0.0053 0.0225 0.0229
Plasmodium vivax flap endonuclease 1, putative 0.0018 0.0023 0.0126
Brugia malayi glutaminase DH11.1 0.029 0.1595 0.1697
Giardia lamblia Flap structure-specific endonuclease 0.0018 0.0023 0.0011
Echinococcus multilocularis transfer RNA-Lys 0.0024 0.0062 0.0062
Leishmania major hypothetical protein, conserved 0.0016 0.0012 0.0012
Trypanosoma brucei dihydrolipoyl dehydrogenase 0.0065 0.0296 0.0304
Schistosoma mansoni hypothetical protein 0.0134 0.0692 0.0736
Brugia malayi tailless protein 0.0064 0.029 0.0308
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0012 0.0047
Mycobacterium ulcerans acetyl-CoA synthetase 0.0021 0.004 0.0129
Loa Loa (eye worm) oxidoreductase 0.0021 0.004 0.0043
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.003 0.0094 0.009
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0019 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0115 0.0584 0.0611
Echinococcus multilocularis ATP dependent DNA helicase Q5 0.0026 0.0069 0.0069
Loa Loa (eye worm) AGC/GRK/BARK protein kinase 0.0082 0.0392 0.0418
Leishmania major cathepsin L-like protease 0.0115 0.0584 0.062
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.002
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0064 0.029 0.029
Echinococcus multilocularis RUN 0.0039 0.0144 0.0144
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0136 0.0704 0.0749
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0136 0.0704 0.0704
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0017 0.002 0.0011
Loa Loa (eye worm) DR-78 0.0064 0.029 0.0308
Brugia malayi hypothetical protein 0.012 0.0613 0.0652
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.1446 0.1529
Schistosoma mansoni regulator of G protein signaling 0.0077 0.0362 0.0385
Loa Loa (eye worm) pyridine nucleotide-disufhide oxidoreductase 0.0017 0.002 0.0021
Schistosoma mansoni pyruvate kinase 0.0017 0.0017 0.0018
Schistosoma mansoni amiloride-sensitive sodium channel-related 0.0134 0.0692 0.0736
Echinococcus multilocularis neuropeptide receptor A26 0.0632 0.3564 0.3564
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0142 0.015
Mycobacterium tuberculosis Probable NADH dehydrogenase Ndh 0.0428 0.239 0.8962
Schistosoma mansoni amiloride-sensitive sodium channel-related 0.0134 0.0692 0.0736
Toxoplasma gondii glycosyl hydrolase, family 31 protein 0.0035 0.0125 0.065
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.1446 0.1529
Trypanosoma cruzi cysteine protease, putative 0.0016 0.001 0.001
Brugia malayi hypothetical protein 0.0039 0.0144 0.0153
Schistosoma mansoni myst-related protein 0.0021 0.004 0.0043
Trypanosoma brucei pyruvate kinase 1 0.0033 0.0109 0.0105
Brugia malayi ORL1-like opioid receptor 0.0017 0.0019 0.002
Loa Loa (eye worm) jmjC domain-containing protein 0.0142 0.074 0.0788
Brugia malayi Voltage-gated potassium channel, HERG (KCNH2)-related. C. elegans unc-103 ortholog 0.0071 0.0327 0.0348
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0329 0.035
Plasmodium falciparum DNase I-like protein, putative 0.0016 0.0012 0.0087
Schistosoma mansoni voltage-gated potassium channel 0.0016 0.0012 0.0012
Brugia malayi ecdysteroid receptor 0.0136 0.0704 0.0749
Loa Loa (eye worm) hypothetical protein 0.0134 0.0692 0.0736
Brugia malayi nuclear hormone receptor 0.0136 0.0704 0.0749
Mycobacterium ulcerans hypothetical protein 0.0025 0.0064 0.0281
Brugia malayi neuropeptide F receptor 0.0017 0.0019 0.002
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0017 0.0019 0.002
Brugia malayi PHD-finger family protein 0.003 0.0094 0.01
Leishmania major pantothenate kinase subunit, putative 0.0019 0.0029 0.0029
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Echinococcus granulosus neutral alpha glucosidase AB 0.0035 0.0125 0.0133
Echinococcus multilocularis sex peptide receptor 0.0017 0.0019 0.0019
Trichomonas vaginalis type II inositol 5-phosphatase, putative 0.0016 0.0012 0.0002
Schistosoma mansoni cpg binding protein 0.0186 0.0992 0.1055
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0209 0.0742
Mycobacterium tuberculosis Dihydrolipoamide dehydrogenase LpdC (lipoamide reductase (NADH)) (lipoyl dehydrogenase) (dihydrolipoyl dehydrogenase) (diaphoras 0.0476 0.2666 1
Echinococcus granulosus neuropeptides capa receptor 0.0017 0.0019 0.002
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0064 0.0288 0.0296
Leishmania major RNA-editing complex protein MP100, putative 0.0016 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0136 0.0704 0.0749
Echinococcus granulosus axis inhibition protein axin 0.0077 0.0362 0.0385
Schistosoma mansoni nocturnin 0.0016 0.0012 0.0013
Echinococcus granulosus histone acetyltransferase KAT2B 0.0144 0.0752 0.0801
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0013
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0012 0.0047
Echinococcus granulosus cathepsin L cysteine protease 0.0016 0.001 0.0011
Entamoeba histolytica hypothetical protein 0.0077 0.0362 0.0374
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0232 0.1258 0.1258
Echinococcus multilocularis cyclic nucleotide gated cation channel 0.0016 0.0012 0.0012
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0019 0.002
Trypanosoma brucei pyruvate kinase 1, putative 0.0033 0.0109 0.0105
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0142 0.015
Toxoplasma gondii histone lysine methyltransferase SET1 0.0339 0.1875 1
Schistosoma mansoni serine/threonine protein kinase 0.1644 0.9398 1
Schistosoma mansoni nuclear hormone receptor 0.0136 0.0704 0.0749
Brugia malayi Serotonin receptor 0.0017 0.0019 0.002
Schistosoma mansoni tar DNA-binding protein 0.0583 0.3282 0.3492
Brugia malayi 3-hydroxyacyl-CoA dehydrogenase type II 0.0043 0.0167 0.0178
Trichomonas vaginalis CAMK family protein kinase 0.1644 0.9398 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.002
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0136 0.0704 0.0749
Schistosoma mansoni 3-hydroxyacyl-CoA dehydrogenase 0.0043 0.0167 0.0178
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0144 0.0749 0.0797
Loa Loa (eye worm) hypothetical protein 0.0308 0.1696 0.1805
Mycobacterium tuberculosis Conserved hypothetical protein 0.0038 0.0142 0.0488
Trichomonas vaginalis CAMK family protein kinase 0.1644 0.9398 1
Mycobacterium ulcerans pyruvate kinase 0.0033 0.0109 0.0565
Echinococcus multilocularis solute carrier family 5 0.0077 0.0367 0.0367
Schistosoma mansoni terminal deoxycytidyl transferase 0.0038 0.0142 0.0151
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0749 0.0797
Echinococcus granulosus tissue type plasminogen activator 0.0017 0.0018 0.0019
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.004 0.0043
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0072 0.0334 0.0334
Loa Loa (eye worm) neuropeptide F receptor 0.0017 0.0019 0.002
Brugia malayi Nuclear hormone receptor E75 0.0064 0.029 0.0308
Echinococcus granulosus Polycystic kidney disease protein 0.0039 0.0144 0.0153
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0115 0.0584 0.0611
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0028 0.0084 0.0079
Brugia malayi Degenerin-like protein ZK770.1 in chromosome I, putative 0.0134 0.0692 0.0736
Plasmodium vivax vivapain-2 0.003 0.0094 0.085
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0136 0.0704 0.0749
Echinococcus granulosus dihydrolipoamide dehydrogenase 0.0065 0.0296 0.0315
Trypanosoma brucei polo-like protein kinase 0.1644 0.9398 1
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0136 0.0704 0.0749
Schistosoma mansoni axis inhibition protein axin 0.0077 0.0362 0.0385
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0921 0.0971
Echinococcus multilocularis amiloride sensitive cation channel 4 A 0.0134 0.0692 0.0692
Echinococcus granulosus Jumonji AT rich interactive domain 1B 0.0045 0.0181 0.0193
Onchocerca volvulus Huntingtin homolog 0.012 0.0613 0.0652
Toxoplasma gondii histone lysine acetyltransferase GCN5-A 0.0044 0.0172 0.0903
Brugia malayi jmjC domain containing protein 0.0035 0.0124 0.0132
Echinococcus multilocularis muscleblind protein 1 0.0108 0.0546 0.0546
Onchocerca volvulus 0.0017 0.0019 0.002
Echinococcus multilocularis cyclic nucleotide gated cation channel alpha 3 0.0016 0.0012 0.0012
Brugia malayi Cathepsin L-like precursor 0.003 0.0094 0.0101
Leishmania major hypothetical protein, conserved 0.0034 0.0114 0.012
Echinococcus multilocularis protein vprbp 0.0134 0.0692 0.0692
Brugia malayi M-phase phosphoprotein, mpp8 0.0062 0.0277 0.0295
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0017 0.002 0.002
Brugia malayi Thioredoxin reductase 0.0188 0.1003 0.1067
Mycobacterium ulcerans aldehyde dehydrogenase 0.019 0.1018 0.634
Echinococcus granulosus bloom syndrome protein 0.0063 0.0281 0.0299
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0017 0.0019 0.002
Brugia malayi Sodium:solute symporter family protein 0.0077 0.0367 0.039
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0375 0.2084 0.2217
Brugia malayi neuropeptide F receptor 0.0017 0.0019 0.002
Onchocerca volvulus 0.0062 0.0277 0.0295
Schistosoma mansoni cpg binding protein 0.0176 0.0934 0.0994
Loa Loa (eye worm) G protein signaling regulator EGL-10 0.0077 0.0362 0.0385
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0094 0.009
Echinococcus multilocularis cysteine protease 0.003 0.0094 0.0094
Mycobacterium tuberculosis P-hydroxybenzoyl-AMP ligase FadD22 0.0021 0.004 0.0107
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0069 0.0354
Trichomonas vaginalis CAMK family protein kinase 0.0814 0.4612 0.4902
Brugia malayi nuclear receptor RXR 0.0072 0.0334 0.0356
Plasmodium vivax SET domain protein, putative 0.0065 0.0294 0.2861
Loa Loa (eye worm) histone methyltransferase 0.0057 0.0247 0.0263
Brugia malayi nuclear receptor NHR-88 0.0136 0.0704 0.0749
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0012 0.0002
Mycobacterium tuberculosis Probable chain -fatty-acid-CoA ligase FadD13 (fatty-acyl-CoA synthetase) 0.0071 0.0329 0.1193
Loa Loa (eye worm) hypothetical protein 0.0072 0.0334 0.0356
Echinococcus multilocularis dnaJ subfamily B 0.1246 0.7104 0.7104
Onchocerca volvulus 0.0021 0.004 0.0043
Schistosoma mansoni z-protein (S1r protein) 0.0077 0.0362 0.0385
Echinococcus multilocularis FMRFamide activated amiloride sensitive sodium 0.0134 0.0692 0.0692
Leishmania major hypothetical protein, conserved 0.0016 0.0012 0.0012
Brugia malayi hypothetical protein 0.0017 0.0019 0.002
Mycobacterium leprae PROBABLE NADH DEHYDROGENASE NDH 0.0428 0.239 0.8958
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0136 0.0704 0.0749
Schistosoma mansoni DNA polymerase eta 0.0038 0.0142 0.0151
Mycobacterium tuberculosis PROBABLE FATTY-ACID-CoA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0018 0.0024 0.0044
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0012 0.0002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0225 0.024
Toxoplasma gondii thioredoxin reductase 0.0188 0.1003 0.5342
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0065 0.0296 0.0314
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Echinococcus multilocularis lysine specific demethylase 5A 0.0132 0.0683 0.0683
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0136 0.0704 0.0749
Brugia malayi AMP-binding enzyme family protein 0.0021 0.004 0.0043
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0077 0.0362 0.0385
Trichomonas vaginalis sphingomyelinase C 2 precursor, putative 0.0016 0.0012 0.0002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.002
Mycobacterium tuberculosis Probable short-chain type dehydrogenase/reductase 0.0043 0.0167 0.0586
Mycobacterium ulcerans endonuclease IV 0.0095 0.0467 0.2841
Schistosoma mansoni myosin xvIII 0.0017 0.0019 0.002
Plasmodium falciparum cysteine proteinase falcipain 1 0.0016 0.001 0.0069
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Leishmania major 2-oxoglutarate dehydrogenase, e3 component, lipoamidedehydrogenase-like protein 0.0065 0.0296 0.0314
Schistosoma mansoni rab6-interacting 0.0039 0.0144 0.0153
Echinococcus granulosus peregrin 0.0065 0.0296 0.0315
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.002
Mycobacterium tuberculosis Peptide synthetase MbtE (peptide synthase) 0.0021 0.004 0.0107
Toxoplasma gondii kringle domain-containing protein 0.0017 0.0018 0.0079
Trichomonas vaginalis glutaminase, putative 0.029 0.1595 0.1688
Leishmania major cathepsin L-like protease 0.003 0.0094 0.01
Plasmodium falciparum AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0079 0.0374 0.3704
Toxoplasma gondii flap structure-specific endonuclease 1, putative 0.0018 0.0023 0.0104
Brugia malayi conserved hypotetical protein 0.0064 0.029 0.0308
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0019 0.002
Plasmodium falciparum JmjC domain-containing protein, putative 0.0035 0.0124 0.1205
Onchocerca volvulus 0.0017 0.0019 0.002
Leishmania major protein kinase, putative,polo-like protein kinase, putative 0.1644 0.9398 1
Loa Loa (eye worm) hypothetical protein 0.0017 0.0017 0.0018
Echinococcus granulosus regulator of G protein signaling 3 0.0077 0.0362 0.0385
Trichomonas vaginalis bromodomain-containing protein, putative 0.0044 0.0172 0.0173
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Onchocerca volvulus 0.0021 0.004 0.0043
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0065 0.0296 0.0314
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0064 0.0288 0.0296
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0136 0.0704 0.0749
Schistosoma mansoni neuropeptide receptor 0.0017 0.0019 0.002
Plasmodium vivax NAD(P)H-dependent glutamate synthase, putative 0.0017 0.002 0.01
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0012 0.0013
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0018
Plasmodium vivax hypothetical protein, conserved 0.0016 0.0012 0.0018
Echinococcus multilocularis thioredoxin glutathione reductase 0.0188 0.1006 0.1006
Loa Loa (eye worm) hypothetical protein 0.0021 0.004 0.0043
Loa Loa (eye worm) hypothetical protein 0.0134 0.0692 0.0736
Schistosoma mansoni glutaminase 0.029 0.1595 0.1697
Onchocerca volvulus 0.0071 0.0329 0.035
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0012 0.0002
Echinococcus granulosus sex peptide receptor 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0385
Echinococcus granulosus sodium:myo inositol cotransporter 0.0077 0.0367 0.039
Echinococcus multilocularis FMRFamide activated amiloride sensitive sodium 0.0134 0.0692 0.0692
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0017 0.0019 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.1446 0.1529
Brugia malayi Protein kinase domain containing protein 0.0015 0.0008 0.0008
Trichomonas vaginalis conserved hypothetical protein 0.004 0.015 0.0149
Leishmania major pyruvate kinase 0.0033 0.0109 0.0115
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Schistosoma mansoni nuclear receptor nhr-48 0.0064 0.029 0.0308
Echinococcus multilocularis fmrfamide receptor 0.0017 0.0019 0.0019
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0109 0.0105
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0114 0.0592
Loa Loa (eye worm) hypothetical protein 0.0136 0.0704 0.0749
Loa Loa (eye worm) hypothetical protein 0.0064 0.029 0.0308
Loa Loa (eye worm) hypothetical protein 0.0017 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0136 0.0704 0.0749
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0065 0.0294 0.0294
Schistosoma mansoni aldehyde dehydrogenase 0.019 0.1018 0.1084
Loa Loa (eye worm) hypothetical protein 0.0134 0.0692 0.0736
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0136 0.0704 0.0749
Echinococcus multilocularis Ankyrin repeat domain containing protein 0.0055 0.0237 0.0237
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0012 0.0012
Trypanosoma brucei long-chain-fatty-acid-CoA ligase, putative 0.0021 0.004 0.0032
Echinococcus multilocularis FMRFamide activated amiloride sensitive sodium 0.0134 0.0692 0.0692
Echinococcus multilocularis cathepsin L 0.0016 0.001 0.001
Schistosoma mansoni thyroid hormone receptor 0.0136 0.0704 0.0749
Plasmodium vivax pyruvate kinase 2, putative 0.0017 0.0017 0.0072
Trypanosoma brucei RNA editing exonuclease 2 0.0016 0.0012 0.0002
Schistosoma mansoni hypothetical protein 0.0062 0.0275 0.0293
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0017 0.0019 0.002
Trichomonas vaginalis CAMK family protein kinase 0.1644 0.9398 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0294 0.0313
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0019 0.002
Brugia malayi Cyclic-nucleotide gated cation channel 0.0016 0.0012 0.0012
Schistosoma mansoni voltage-gated potassium channel 0.0077 0.0363 0.0386
Echinococcus granulosus neutral sphingomyelinase 0.0016 0.0012 0.0013
Loa Loa (eye worm) hypothetical protein 0.0039 0.0144 0.0153
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Brugia malayi Pyruvate kinase, muscle isozyme 0.0033 0.0109 0.0116
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0142 0.014
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0019
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0144 0.0153
Loa Loa (eye worm) 3-hydroxyacyl-CoA dehydrogenase type II 0.0036 0.013 0.0139
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0065 0.0294 0.0294
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0144 0.0749 0.0797
Mycobacterium ulcerans epimerase 0.0025 0.0064 0.0281
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0017 0.0017 0.0018
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0329 0.1959
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0142 0.0772
Plasmodium falciparum ADP-dependent DNA helicase RecQ 0.0055 0.0237 0.2342
Schistosoma mansoni aldehyde dehydrogenase 0.019 0.1018 0.1084
Plasmodium falciparum pyruvate kinase 0.0033 0.0109 0.1059
Onchocerca volvulus Putative hydroxypyruvate isomerase 0.0025 0.0064 0.0068
Echinococcus granulosus A kinase anchor protein 10 mitochondrial 0.0077 0.0362 0.0385
Brugia malayi Melatonin receptor type 1A 0.0017 0.0019 0.002
Brugia malayi PHD-finger family protein 0.0062 0.0275 0.0293
Schistosoma mansoni histamine h1 receptor 0.0017 0.0019 0.002
Echinococcus multilocularis 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0043 0.0167 0.0167
Echinococcus multilocularis cathepsin l cysteine peptidase 0.003 0.0094 0.0094
Echinococcus granulosus lysine specific demethylase 5A 0.0142 0.074 0.0788
Schistosoma mansoni regulator of G protein signaling 0.0077 0.0362 0.0385
Echinococcus granulosus neuropeptide receptor A26 0.0632 0.3564 0.3793
Brugia malayi AKH receptor 0.0017 0.0019 0.002
Loa Loa (eye worm) PXA domain-containing protein 0.0077 0.0362 0.0385
Schistosoma mansoni lipoxygenase 0.0162 0.0855 0.091
Schistosoma mansoni synaptojanin 0.0016 0.0012 0.0013
Loa Loa (eye worm) papain family cysteine protease containing protein 0.003 0.0094 0.0101
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0012 0.0013
Mycobacterium tuberculosis Probable pyruvate kinase PykA 0.0033 0.0109 0.0366
Echinococcus granulosus 3 hydroxyacyl coenzyme A dehydrogenase type 2 0.0043 0.0167 0.0178
Brugia malayi glutamate synthase 0.0017 0.002 0.0021
Echinococcus multilocularis chromodomain helicase DNA binding protein 4 0.0017 0.0018 0.0018
Echinococcus granulosus pyruvate kinase 0.0017 0.0017 0.0018
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0125 0.0122
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0362 0.0374
Echinococcus multilocularis serine:threonine protein kinase PLK1 0.1644 0.9398 0.9398
Schistosoma mansoni coup transcription factor 0.0136 0.0704 0.0749
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.004 0.0032
Entamoeba histolytica pyruvate kinase, putative 0.0023 0.0052 0.0045
Echinococcus granulosus cyclic nucleotide gated cation channel alpha 3 0.0016 0.0012 0.0012
Loa Loa (eye worm) CCR4-NOT transcription complex subunit 6 family protein 0.0016 0.0012 0.0013
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0012 0.0012
Schistosoma mansoni hypothetical protein 0.0134 0.0692 0.0736
Plasmodium falciparum thioredoxin reductase 0.0065 0.0296 0.2924
Trichomonas vaginalis chromodomain-helicase-DNA-binding protein, putative 0.0047 0.019 0.0192
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Brugia malayi Degenerin-like protein C41C4.5 in chromosome II, putative 0.0134 0.0692 0.0736
Schistosoma mansoni regulator of G protein signaling 0.0077 0.0362 0.0385
Giardia lamblia PHD finger protein 15 0.0062 0.0275 0.0281
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0012 0.0002
Toxoplasma gondii histone lysine demethylase JMJD6a 0.0035 0.0124 0.0644
Loa Loa (eye worm) RecQ helicase 0.0063 0.0281 0.0299
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0017 0.0019 0.0019
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0017 0.0017 0.0018
Entamoeba histolytica disulphide oxidoreductase, putative 0.0017 0.002 0.0011
Chlamydia trachomatis endonuclease IV 0.0095 0.0467 1
Onchocerca volvulus 0.0134 0.0692 0.0736
Trichomonas vaginalis conserved hypothetical protein 0.004 0.015 0.0149
Echinococcus multilocularis thyroid hormone receptor alpha 0.0136 0.0704 0.0704
Trypanosoma brucei unspecified product 0.0038 0.0142 0.014
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0012 0.0002
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0012 0.0047
Trichomonas vaginalis neutral alpha-glucosidase ab precursor, putative 0.0035 0.0125 0.0122
Loa Loa (eye worm) voltage and ligand gated potassium channel 0.0071 0.0327 0.0348
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0048 0.0051
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Echinococcus granulosus cathepsin l1 0.002 0.0037 0.0039
Entamoeba histolytica cysteine protease, putative 0.003 0.0094 0.009
Brugia malayi hypothetical protein 0.0111 0.0561 0.0597
Loa Loa (eye worm) doublecortin family protein 0.0039 0.0144 0.0153
Trichomonas vaginalis glutathione reductase, putative 0.0065 0.0296 0.0304
Brugia malayi hypothetical protein 0.0017 0.0019 0.002
Brugia malayi glutathione reductase 0.0188 0.1003 0.1067
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0125 0.0122
Loa Loa (eye worm) cytochrome P450 family protein 0.0018 0.0026 0.0027
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0072 0.0334 0.0356
Onchocerca volvulus 0.0039 0.0144 0.0153
Mycobacterium tuberculosis Probable medium chain fatty-acid-CoA ligase FadD14 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.004 0.0107
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0022 0.0048 0.0051
Loa Loa (eye worm) hypothetical protein 0.0136 0.0704 0.0749
Echinococcus multilocularis high affinity choline transporter 1 0.0702 0.3966 0.3966
Brugia malayi ecdysone receptor 0.0064 0.029 0.0308
Echinococcus granulosus FTZ F1 alpha 0.0136 0.0704 0.0749
Echinococcus granulosus Ankyrin repeat domain containing protein 0.0055 0.0237 0.0252
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0125 0.0132
Trypanosoma brucei inositol-1,4,5-trisphosphate (IP3) 5-phosphatase, putative 0.0016 0.0012 0.0002
Plasmodium vivax dihydrolipoyl dehydrogenase, mitochondrial, putative 0.0065 0.0296 0.2875
Trypanosoma cruzi cysteine peptidase, putative 0.003 0.0094 0.01
Echinococcus multilocularis traf and tnf receptor associated protein 0.0016 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.004 0.015 0.0149
Plasmodium falciparum cysteine proteinase falcipain 2a 0.003 0.0094 0.0913
Onchocerca volvulus 0.0017 0.0018 0.0019
Echinococcus multilocularis FMRFamide activated amiloride sensitive sodium 0.0134 0.0692 0.0692
Loa Loa (eye worm) hypothetical protein 0.0108 0.0546 0.0581
Trypanosoma brucei dihydrolipoamide dehydrogenase, point mutation 0.0065 0.0296 0.0304
Mycobacterium tuberculosis Probable dehydrogenase 0.0428 0.239 0.8962
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0024 0.0057 0.0061
Toxoplasma gondii Erv1 / Alr family protein 0.0034 0.0114 0.0592
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0019 0.002
Echinococcus granulosus pyruvate kinase 0.0017 0.0017 0.0018
Schistosoma mansoni biogenic amine receptor 0.0017 0.0019 0.002
Loa Loa (eye worm) cyclic-nucleotide gated cation channel 0.0016 0.0012 0.0012
Schistosoma mansoni regulator of G protein signaling 0.0077 0.0362 0.0385
Echinococcus granulosus tm gpcr rhodopsin 0.0017 0.0019 0.002
Mycobacterium tuberculosis Possible dehydrogenase/reductase 0.0017 0.002 0.0031
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD7 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0329 0.1166
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.019 0.0192
Plasmodium falciparum apurinic/apyrimidinic endonuclease Apn1, putative 0.0095 0.0467 0.4643
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0017 0.0019 0.002
Echinococcus granulosus Nuclear hormone receptor HR96 0.0064 0.029 0.0308
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0017 0.0019 0.002
Onchocerca volvulus Cathepsin F homolog 0.003 0.0094 0.0101
Echinococcus granulosus amiloride sensitive cation channel 4 A 0.0134 0.0692 0.0736
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0017 0.0019 0.0019
Entamoeba histolytica endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0012 0.0002
Brugia malayi Cathepsin L-like precursor 0.003 0.0094 0.0101
Leishmania major acetoin dehydrogenase e3 component-like protein 0.0065 0.0296 0.0314
Brugia malayi jmjC domain containing protein 0.0142 0.074 0.0788
Brugia malayi dihydrolipoyl dehydrogenase, mitochondrial precursor, putative 0.0065 0.0296 0.0315
Onchocerca volvulus 0.0017 0.0019 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0129
Plasmodium vivax hypothetical protein, conserved 0.0031 0.0098 0.0888
Brugia malayi hypothetical protein 0.0077 0.0362 0.0385
Schistosoma mansoni pyruvate kinase 0.0033 0.0109 0.0116
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0017 0.0019 0.002
Loa Loa (eye worm) latrophilin receptor protein 2 0.0017 0.0017 0.0018
Brugia malayi SET domain containing protein 0.0016 0.0013 0.0014
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0136 0.0704 0.0749
Loa Loa (eye worm) hypothetical protein 0.0064 0.029 0.0308
Plasmodium vivax multidomain scavenger receptor, putative 0.0039 0.0144 0.1348
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0073 0.0067
Schistosoma mansoni hypothetical protein 0.0017 0.002 0.0021
Echinococcus granulosus sulfide:quinone oxidoreductase 0.0017 0.002 0.0021
Loa Loa (eye worm) hepatopoietin HPO2 0.0034 0.0114 0.0121
Onchocerca volvulus 0.0017 0.0019 0.002
Mycobacterium ulcerans DNA polymerase IV 0.0038 0.0142 0.0772
Brugia malayi exodeoxyribonuclease III family protein 0.0079 0.0374 0.0397
Onchocerca volvulus 0.0136 0.0704 0.0749
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0109 0.0116
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0125 0.0122
Brugia malayi Cathepsin L-like precursor 0.003 0.0094 0.0101
Mycobacterium tuberculosis Probable NADPH dependent 2,4-dienoyl-CoA reductase FadH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) 0.0017 0.002 0.0031
Loa Loa (eye worm) RNA binding protein 0.0583 0.3282 0.3492
Chlamydia trachomatis dihydrolipoyl dehydrogenase 0.0065 0.0296 0.616
Mycobacterium ulcerans hypothetical protein 0.0071 0.0329 0.1959
Schistosoma mansoni ubiquitously transcribed sex (X/Y) chromosome tetratricopeptide repeat protein-related 0.0035 0.0124 0.0132
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0027 0.0018
Entamoeba histolytica hypothetical protein 0.0077 0.0362 0.0374
Trichomonas vaginalis DNA helicase recq, putative 0.0033 0.0113 0.011
Echinococcus granulosus sodium:glucose cotransporter 0.0077 0.0367 0.039
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0129
Mycobacterium ulcerans non-ribosomal peptide synthetase MbtF 0.0021 0.004 0.0129
Loa Loa (eye worm) hypothetical protein 0.0071 0.0329 0.035
Plasmodium falciparum acyl-CoA synthetase 0.0053 0.0225 0.2222
Echinococcus granulosus traf and tnf receptor associated protein 0.0016 0.0012 0.0013
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0921 0.0971
Echinococcus granulosus neuropeptide s receptor 0.0632 0.3564 0.3793
Brugia malayi amiloride-sensitive sodium channel alpha-subunit, putative 0.0134 0.0692 0.0736
Schistosoma mansoni cript-related 0.0016 0.0012 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.002
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0017 0.002 0.0021
Giardia lamblia Pyruvate kinase 0.0017 0.0017 0.0006
Echinococcus multilocularis axis inhibition protein axin 0.0077 0.0362 0.0362
Trichomonas vaginalis ap endonuclease, putative 0.0079 0.0374 0.0387
Leishmania major hypothetical protein, conserved 0.0053 0.0225 0.0239
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0225 0.222
Echinococcus granulosus potassium:sodium hyperpolarization activated 0.0016 0.0012 0.0012
Onchocerca volvulus Glucosylceramidase homolog 0.0174 0.0921 0.098
Onchocerca volvulus 0.0017 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0071 0.0329 0.035
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0136 0.0704 0.0749
Leishmania major NADH dehydrogenase, putative 0.0017 0.002 0.002
Brugia malayi Augmenter of liver regeneration 0.0034 0.0114 0.0121
Leishmania major dihydrolipoamide dehydrogenase, putative 0.0065 0.0296 0.0314
Schistosoma mansoni serine/threonine protein kinase 0.0014 0.0003 0.0003
Mycobacterium tuberculosis Fatty-acid-AMP ligase FadD30 (fatty-acid-AMP synthetase) (fatty-acid-AMP synthase) 0.0053 0.0225 0.0804
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.003 0.0094 0.009
Toxoplasma gondii ATP-dependent DNA helicase, RecQ family protein 0.0026 0.0069 0.0354
Schistosoma mansoni tar DNA-binding protein 0.0583 0.3282 0.3492
Trypanosoma brucei inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0012 0.0002
Leishmania major inositol phosphosphingolipid phospholipase C-Like 0.0016 0.0012 0.0012
Trichomonas vaginalis conserved hypothetical protein 0.004 0.015 0.0149
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0017 0.0019 0.002
Entamoeba histolytica glutamate synthase beta subunit, putative 0.0017 0.002 0.0011
Trypanosoma cruzi polo-like protein kinase, putative 0.1644 0.9398 1
Trypanosoma cruzi dihydrolipoyl dehydrogenase, putative 0.0065 0.0296 0.0314
Schistosoma mansoni ap endonuclease 0.0079 0.0374 0.0397
Schistosoma mansoni opsin-like receptor 0.0017 0.0019 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.019 0.0192
Schistosoma mansoni acetyl-CoA synthetase 0.0021 0.004 0.0043
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Mycobacterium tuberculosis Probable thioredoxin reductase TrxB2 (TRXR) (TR) 0.0017 0.002 0.0031
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0027 0.0079 0.0084
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0036 0.0028
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0012 0.0012
Trichomonas vaginalis cat eye syndrome critical region protein 2, cscr2, putative 0.0044 0.0172 0.0173
Trichomonas vaginalis antibiotic synthetase, putative 0.0021 0.004 0.0032
Loa Loa (eye worm) hypothetical protein 0.0022 0.0048 0.0051
Mycobacterium ulcerans cytochrome P450 185A4 Cyp185A4 0.0018 0.0026 0.0035
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0209 0.0742
Plasmodium falciparum conserved Plasmodium membrane protein, unknown function 0.0031 0.0098 0.0951
Schistosoma mansoni cathepsin F (C01 family) 0.003 0.0094 0.0101
Echinococcus granulosus chromodomain helicase DNA binding protein 4 0.0017 0.0018 0.002
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0144 0.0749 0.0749
Brugia malayi photoreceptor-specific nuclear receptor 0.0136 0.0704 0.0749
Schistosoma mansoni flap endonuclease-1 0.0016 0.0013 0.0014
Brugia malayi Nuclear hormone receptor-like 1 0.0136 0.0704 0.0749
Toxoplasma gondii NADH dehydrogenase (NDH2-II) 0.0017 0.002 0.009
Echinococcus multilocularis Na+ channel, amiloride sensitive 0.0134 0.0692 0.0692
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0012 0.0002
Plasmodium vivax glutathione reductase, putative 0.0188 0.1003 1
Loa Loa (eye worm) hypothetical protein 0.0025 0.0064 0.0068
Loa Loa (eye worm) glutaminase 2 0.029 0.1595 0.1697
Brugia malayi Muscleblind-like protein 0.0108 0.0546 0.0581
Mycobacterium leprae PROBABLE ENDONUCLEASE IV END (ENDODEOXYRIBONUCLEASE IV) (APURINASE) 0.0095 0.0467 0.1691
Schistosoma mansoni high-affinity choline transporter 0.0702 0.3966 0.422
Trypanosoma brucei DNA polymerase eta, putative 0.0038 0.0142 0.014
Brugia malayi PAS domain containing protein 0.0033 0.0111 0.0118
Leishmania major pyruvate kinase 0.0033 0.0109 0.0115
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0842 0.0842
Echinococcus multilocularis ATP dependent DNA helicase Q1 0.0026 0.0069 0.0069
Mycobacterium tuberculosis Fatty-acid-CoA synthetase FadD17 (fatty-acid-CoA synthase) (fatty-acid-CoA ligase) 0.0021 0.004 0.0107
Toxoplasma gondii WD domain, G-beta repeat-containing protein 0.002 0.0036 0.0178
Brugia malayi NADPH:adrenodoxin oxidoreductase, mitochondrial precursor 0.0017 0.002 0.0021
Loa Loa (eye worm) amiloride-sensitive sodium channel 0.0134 0.0692 0.0736
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0017 0.0019 0.002
Echinococcus multilocularis tumor protein p63 0.0189 0.1011 0.1011
Loa Loa (eye worm) TYRA-2 protein 0.0017 0.0019 0.002
Echinococcus granulosus Transcription factor JmjC domain containing protein 0.0259 0.1416 0.1506
Onchocerca volvulus 0.0017 0.0019 0.002
Echinococcus granulosus lipoxygenase domain containing protein 0.0039 0.0144 0.0153
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0115 0.0584 0.0611
Echinococcus multilocularis terminal deoxycytidyl transferase rev1 0.0038 0.0142 0.0142
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0921 0.0971
Schistosoma mansoni retinoic acid receptor RXR 0.0136 0.0704 0.0749
Echinococcus granulosus neuropeptide FF receptor 2 0.0017 0.0019 0.002
Onchocerca volvulus Huntingtin homolog 0.012 0.0613 0.0652
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0129
Loa Loa (eye worm) hypothetical protein 0.0035 0.0124 0.0132
Leishmania major 2,4-dienoyl-coa reductase fadh1, putative 0.0017 0.002 0.002
Schistosoma mansoni hypothetical protein 0.1019 0.5797 0.6168
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.004 0.0042
Trichomonas vaginalis dihydrolipoamide dehydrogenase, putative 0.0017 0.002 0.0011
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.0064 0.029 0.029
Giardia lamblia Pyruvate kinase 0.0033 0.0109 0.0103
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0053 0.0225 0.1304
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.0064 0.029 0.029
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0017 0.0019 0.0019
Schistosoma mansoni amiloride-sensitive sodium channel-related 0.0134 0.0692 0.0736
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0012 0.0013
Mycobacterium ulcerans dihydrolipoamide dehydrogenase 0.0065 0.0296 0.175
Entamoeba histolytica hypothetical protein 0.0039 0.0143 0.0141
Trypanosoma cruzi apurinic/apyrimidinic endonuclease 0.0079 0.0374 0.0397
Plasmodium vivax exodeoxyribonuclease III, putative 0.0016 0.0012 0.0018
Brugia malayi jmjC domain containing protein 0.0035 0.0124 0.0132
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0012 0.0002
Onchocerca volvulus 0.0016 0.0012 0.0013
Mycobacterium ulcerans aldehyde dehydrogenase 0.019 0.1018 0.634
Trichomonas vaginalis glucosylceramidase, putative 0.0183 0.0975 0.1028
Trypanosoma brucei PHD-zinc-finger like domain containing protein, putative 0.002 0.0036 0.0028
Echinococcus multilocularis regulator of G protein signaling 0.0077 0.0362 0.0362
Toxoplasma gondii selenide, water dikinase 0.0017 0.002 0.009
Onchocerca volvulus 0.0024 0.0062 0.0066
Plasmodium falciparum FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0114 0.1108
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0136 0.0704 0.0749
Plasmodium vivax ADP-dependent DNA helicase RecQ, putative 0.0042 0.0164 0.1553
Loa Loa (eye worm) hypothetical protein 0.0077 0.0367 0.039
Schistosoma mansoni inositol transporter 0.0077 0.0367 0.039
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0072 0.0334 0.0356
Leishmania major acetyl-CoA synthetase, putative 0.0021 0.004 0.0042
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0064 0.029 0.0308
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0017 0.0019 0.002
Schistosoma mansoni steroid hormone receptor ad4bp 0.0136 0.0704 0.0749
Giardia lamblia Thioredoxin reductase 0.0017 0.002 0.0009
Plasmodium vivax dihydrolipoyl dehydrogenase, apicoplast, putative 0.0065 0.0296 0.2875
Echinococcus granulosus potassium voltage gated channel subfamily H 0.0071 0.0327 0.0348
Loa Loa (eye worm) hypothetical protein 0.0028 0.008 0.0085
Echinococcus granulosus dro:myosuppressin receptor 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Trypanosoma cruzi cysteine proteinase, putative 0.0016 0.001 0.001
Echinococcus multilocularis Na+ channel, amiloride sensitive 0.0134 0.0692 0.0692
Schistosoma mansoni hypothetical protein 0.0039 0.0143 0.0152
Echinococcus granulosus biogenic amine 5HT receptor 0.0017 0.0019 0.002
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0012 0.0047
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0053 0.0225 0.024
Trichomonas vaginalis dihydropyrimidine dehydrogenase, putative 0.0017 0.002 0.0011
Trypanosoma brucei flap endonuclease-1 (FEN-1), putative 0.0018 0.0023 0.0013
Echinococcus multilocularis orexin receptor type 2 0.0017 0.0019 0.0019
Mycobacterium ulcerans acyl-CoA synthetase 0.0071 0.0329 0.1959
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.002
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0065 0.0296 0.0314
Loa Loa (eye worm) RGS-3 protein 0.0077 0.0362 0.0385
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0142 0.014
Trypanosoma cruzi long-chain-fatty-acid-CoA ligase, putative 0.0021 0.004 0.0042
Entamoeba histolytica hypothetical protein 0.0021 0.004 0.0032
Brugia malayi hypothetical protein 0.0017 0.0019 0.002
Onchocerca volvulus 0.0017 0.0019 0.002
Schistosoma mansoni alpha-glucosidase 0.0138 0.0713 0.0759
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0017 0.0019 0.002
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0019 0.002
Schistosoma mansoni hypothetical protein 0.0134 0.0692 0.0736
Brugia malayi hypothetical protein 0.0017 0.0019 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0094 0.009
Entamoeba histolytica thioredoxin reductase, putative 0.0017 0.002 0.0011
Schistosoma mansoni neuropeptide F-like receptor 0.0017 0.0019 0.002
Echinococcus granulosus RUN 0.0039 0.0144 0.0153
Loa Loa (eye worm) TK/ROR protein kinase 0.0017 0.0018 0.0019
Echinococcus multilocularis dro:myosuppressin receptor 0.0017 0.0019 0.0019
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0136 0.0704 0.0749
Onchocerca volvulus 0.003 0.0094 0.0101
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0018
Onchocerca volvulus 0.003 0.0094 0.0101
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0017 0.0019 0.002
Trichomonas vaginalis carbon catabolite repressor protein, putative 0.0016 0.0012 0.0002
Entamoeba histolytica inositol polyphosphate-5-phosphatase, putative 0.0016 0.0012 0.0002
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0012 0.0002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Schistosoma mansoni nuclear receptor 0.0064 0.029 0.0308
Schistosoma mansoni rab6-interacting 0.0039 0.0144 0.0153
Echinococcus multilocularis FMRFamide activated amiloride sensitive sodium 0.0134 0.0692 0.0692
Brugia malayi larval opioid receptor 0.0017 0.0019 0.002
Brugia malayi hypothetical protein 0.0072 0.0334 0.0356
Leishmania major 2,4-dienoyl-coa reductase-like protein 0.0017 0.002 0.002
Plasmodium falciparum ataxin-2 like protein, putative 0.0053 0.0225 0.222
Schistosoma mansoni biogenic amine receptor 0.0017 0.0019 0.002
Echinococcus multilocularis G-protein coupled receptor, putative 0.0017 0.0019 0.0019
Onchocerca volvulus 0.003 0.0094 0.0101
Echinococcus granulosus Regulator of G protein signaling 20 0.0077 0.0362 0.0385
Echinococcus multilocularis pyruvate kinase 0.0026 0.0069 0.0069
Loa Loa (eye worm) CXXC zinc finger family protein 0.0176 0.0934 0.0994
Loa Loa (eye worm) hypothetical protein 0.003 0.0094 0.0101
Echinococcus granulosus voltage gated potassium channel 0.0022 0.0048 0.0051
Loa Loa (eye worm) hypothetical protein 0.0072 0.0334 0.0356
Brugia malayi Nuclear hormone receptor E75 0.0064 0.029 0.0308
Loa Loa (eye worm) hypothetical protein 0.0064 0.029 0.0308
Schistosoma mansoni opsin-like receptor 0.0017 0.0019 0.002
Mycobacterium ulcerans aldehyde dehydrogenase 0.019 0.1018 0.634
Trypanosoma cruzi DNA polymerase eta, putative 0.0038 0.0142 0.015
Schistosoma mansoni neutral sphingomyelinase 0.0016 0.0012 0.0013
Schistosoma mansoni phosphatidylserine receptor 0.0035 0.0124 0.0132
Trypanosoma cruzi cysteine peptidase, putative 0.0115 0.0584 0.062
Entamoeba histolytica Flap nuclease, putative 0.0018 0.0023 0.0013
Echinococcus multilocularis neuropeptide Y receptor 0.0017 0.0019 0.0019
Echinococcus multilocularis ecdysone induced protein 78C 0.0136 0.0704 0.0704
Echinococcus multilocularis muscleblind protein 0.0108 0.0546 0.0546
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.002
Onchocerca volvulus 0.0134 0.0692 0.0736
Echinococcus multilocularis FTZ F1 alpha 0.0136 0.0704 0.0704
Echinococcus granulosus g protein coupled receptor 0.0017 0.0019 0.002
Echinococcus granulosus jumonji domain containing 1A 0.0035 0.0124 0.0132
Schistosoma mansoni polycystin 1-related 0.0039 0.0144 0.0153
Trypanosoma brucei glucosidase, putative 0.0035 0.0125 0.0122
Brugia malayi Cathepsin L-like precursor 0.003 0.0094 0.0101
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Brugia malayi acetyl-Coenzyme A synthetase 2 0.0021 0.004 0.0043
Schistosoma mansoni sodium/solute symporter 0.0077 0.0367 0.039
Leishmania major cathepsin L-like protease 0.003 0.0094 0.01
Brugia malayi steroid hormone receptor 0.0136 0.0704 0.0749
Brugia malayi AMP-binding enzyme family protein 0.0071 0.0329 0.035
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0136 0.0704 0.0749
Echinococcus multilocularis FAD linked sulfhydryl oxidase ALR 0.0034 0.0114 0.0114
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0142 0.014
Brugia malayi nuclear hormone receptor 0.0064 0.029 0.0308
Echinococcus multilocularis potassium:sodium hyperpolarization activated 0.0016 0.0012 0.0012
Brugia malayi Cathepsin L-like precursor 0.002 0.0037 0.0039
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0017 0.0019 0.002
Onchocerca volvulus 0.0488 0.2733 0.2908
Trichomonas vaginalis conserved hypothetical protein 0.0018 0.0027 0.0018
Loa Loa (eye worm) steroid hormone receptor 0.0136 0.0704 0.0749
Brugia malayi jmjC domain containing protein 0.0035 0.0124 0.0132
Brugia malayi Cathepsin L-like precursor 0.003 0.0094 0.0101
Echinococcus granulosus endonuclease exonuclease phosphatase 0.0016 0.0012 0.0013
Toxoplasma gondii pyridine nucleotide-disulfide oxidoreductase domain-containing protein 0.0017 0.002 0.009
Toxoplasma gondii AMP-binding enzyme domain-containing protein 0.0021 0.004 0.0198
Brugia malayi hypothetical protein 0.0072 0.0334 0.0356
Mycobacterium tuberculosis Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI) 0.0079 0.0374 0.1363
Echinococcus granulosus cathepsin l1 0.003 0.0094 0.0101
Echinococcus multilocularis neuropeptide FF receptor 2 0.0017 0.0019 0.0019
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0109 0.0116
Schistosoma mansoni DNA helicase recq1 0.0026 0.0069 0.0074
Brugia malayi CCR4 0.0016 0.0012 0.0013
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD1 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.004 0.0107
Plasmodium falciparum dihydrolipoyl dehydrogenase, apicoplast 0.0065 0.0296 0.2924
Onchocerca volvulus 0.003 0.0094 0.0101
Schistosoma mansoni cyclic-nucleotide-gated cation channel 0.0016 0.0012 0.0012
Echinococcus multilocularis phd:f box containing protein 0.0035 0.0124 0.0124
Loa Loa (eye worm) jmjC domain-containing protein 0.0035 0.0124 0.0132
Trypanosoma brucei unspecified product 0.0026 0.0073 0.0067
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0014 0.0003 0.0003
Treponema pallidum oxidoreductase 0.0017 0.002 0.0224
Brugia malayi Papain family cysteine protease containing protein 0.003 0.0094 0.0101
Echinococcus multilocularis cGMP dependent protein kinase 1 0.0014 0.0003 0.0003
Brugia malayi Dopamine receptor protein 1 0.0017 0.0019 0.002
Echinococcus granulosus axis inhibition protein axin 0.0077 0.0362 0.0385
Onchocerca volvulus Cathepsin L homolog 0.003 0.0094 0.0101
Trichomonas vaginalis glucosylceramidase, putative 0.0174 0.0921 0.0971
Schistosoma mansoni amine GPCR 0.0017 0.0019 0.002
Leishmania major aldehyde dehydrogenase, mitochondrial precursor 0.019 0.1018 0.1083
Brugia malayi Voltage-gated potassium channel, EAG (KCNH1)-related. C. elegans egl-2 ortholog 0.0022 0.0048 0.0051
Trichomonas vaginalis ocrl type II inositol 5-phosphatase, putative 0.0016 0.0012 0.0002
Echinococcus granulosus single minded 2 0.0031 0.0098 0.0104
Schistosoma mansoni opsin-like receptor 0.0017 0.0019 0.002
Toxoplasma gondii cathepsin CPL 0.003 0.0094 0.0488
Mycobacterium tuberculosis Possible fatty-acid-CoA ligase FadD10 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.004 0.0107
Loa Loa (eye worm) hypothetical protein 0.0121 0.0618 0.0657
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0136 0.0704 0.0749
Echinococcus granulosus regulator of G protein signaling 7 0.0077 0.0362 0.0385
Schistosoma mansoni sulfide quinone reductase 0.0017 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0115 0.0584 0.0611
Brugia malayi Nuclear hormone receptor-like 1 0.0072 0.0334 0.0356
Loa Loa (eye worm) hypothetical protein 0.0062 0.0275 0.0293
Echinococcus multilocularis rhodopsin orphan GPCR 0.0017 0.0019 0.0019
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.002
Brugia malayi Bromodomain containing protein 0.0065 0.0296 0.0315
Entamoeba histolytica serine/threonine protein kinase, putative 0.1644 0.9398 1
Onchocerca volvulus 0.0017 0.0019 0.002
Echinococcus multilocularis gcn5proteinral control of amino acid synthesis 0.0148 0.0776 0.0776
Trypanosoma cruzi pantothenate kinase subunit, putative 0.0019 0.0029 0.0029
Schistosoma mansoni glutamate synthase 0.0017 0.002 0.0021
Brugia malayi RNA recognition motif domain containing protein 0.0583 0.3282 0.3492
Brugia malayi Glycosyl hydrolases family 31 protein 0.0035 0.0125 0.0133
Onchocerca volvulus 0.003 0.0094 0.0101
Echinococcus multilocularis cathepsin l cysteine peptidase 0.003 0.0094 0.0094
Plasmodium vivax JmjC domain containing protein 0.0035 0.0124 0.1144
Echinococcus granulosus amiloride sensitive sodium channel 0.0134 0.0692 0.0736
Leishmania major ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0113 0.0119
Echinococcus multilocularis neutral alpha glucosidase AB 0.0035 0.0125 0.0125
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Leishmania major hypothetical protein, conserved 0.0017 0.002 0.002
Brugia malayi Cytochrome P450 family protein 0.0018 0.0026 0.0027
Onchocerca volvulus 0.0308 0.1696 0.1805
Brugia malayi RNA binding protein 0.0583 0.3282 0.3492
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0136 0.0704 0.0749
Loa Loa (eye worm) hypothetical protein 0.0038 0.0142 0.0151
Schistosoma mansoni bromodomain-containing nuclear protein 1 brd1 0.0062 0.0275 0.0293
Echinococcus granulosus hyperpolarization activated cyclic 0.0016 0.0012 0.0012
Leishmania major hypothetical protein, conserved 0.0017 0.002 0.002
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0392 0.0418
Echinococcus multilocularis tar DNA binding protein 0.0583 0.3282 0.3282
Mycobacterium ulcerans peptide synthetase Nrp (peptide synthase) 0.0021 0.004 0.0129
Trypanosoma cruzi cysteine peptidase (N-terminal), putative 0.0016 0.001 0.001
Brugia malayi Pre-SET motif family protein 0.0065 0.0294 0.0313
Loa Loa (eye worm) hypothetical protein 0.0064 0.029 0.0308
Echinococcus multilocularis FMRFamide activated amiloride sensitive sodium 0.0134 0.0692 0.0692
Onchocerca volvulus 0.003 0.0094 0.0101
Brugia malayi nuclear receptor NHR-88 0.0064 0.029 0.0308
Loa Loa (eye worm) hypothetical protein 0.0053 0.0225 0.024
Brugia malayi follicle stimulating hormone receptor 0.0017 0.0019 0.002
Mycobacterium leprae PROBABLE FATTY-ACID-CoA LIGASE FADD2 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) 0.0071 0.0329 0.1166
Schistosoma mansoni nuclear hormone receptor 0.0064 0.029 0.0308
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.002
Leishmania major long-chain-fatty-acid-CoA ligase, putative 0.0021 0.004 0.0042
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0142 0.015
Schistosoma mansoni hypothetical protein 0.0134 0.0692 0.0736
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0046 0.0185 0.0185
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0017 0.0019 0.002
Echinococcus multilocularis amiloride sensitive cation channel acid sensing ion channel pituitary 0.0134 0.0692 0.0692
Brugia malayi bHLH-PAS transcription factor 0.0024 0.0062 0.0066
Giardia lamblia NADH oxidase lateral transfer candidate 0.0065 0.0296 0.0302
Schistosoma mansoni protein phosphatase 2C 0.0035 0.0124 0.0132
Mycobacterium ulcerans exodeoxyribonuclease III protein XthA 0.0079 0.0374 0.2245
Echinococcus granulosus 7TM GPCR rhodopsin 0.0017 0.0019 0.002
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0136 0.0704 0.0749
Brugia malayi serine/threonine-protein kinase plk-2 0.1644 0.9398 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0017 0.0019 0.002
Echinococcus multilocularis neuropeptide s receptor 0.0632 0.3564 0.3564
Echinococcus multilocularis Nuclear hormone receptor HR96 0.0064 0.029 0.029
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0017 0.0019 0.002
Loa Loa (eye worm) ImpB/MucB/SamB family protein 0.0038 0.0142 0.0151
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0142 0.014
Treponema pallidum thioredoxin reductase (trxB) 0.0017 0.002 0.0224
Echinococcus multilocularis dna polymerase kappa 0.0038 0.0142 0.0142
Echinococcus granulosus ATP dependent DNA helicase Q5 0.0026 0.0069 0.0074
Schistosoma mansoni alpha-1 adrenergic receptor 0.0017 0.0019 0.002
Brugia malayi hypoxia-induced factor 1 0.0102 0.0511 0.0544
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Echinococcus granulosus fmrfamide receptor 0.0017 0.0019 0.002
Mycobacterium tuberculosis NADPH:adrenodoxin oxidoreductase FprA (NADPH-ferredoxin reductase) 0.0017 0.002 0.0031
Toxoplasma gondii pyruvate dehydrogenase complex subunit PDH-E3II 0.0065 0.0296 0.1562
Loa Loa (eye worm) hypothetical protein 0.0136 0.0704 0.0749
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0109 0.0115
Chlamydia trachomatis acylglycerophosphoethanolamine acyltransferase 0.0053 0.0225 0.459
Trichomonas vaginalis flap endonuclease-1, putative 0.0018 0.0023 0.0013
Echinococcus multilocularis lysosomal alpha glucosidase 0.016 0.0842 0.0842
Loa Loa (eye worm) hypothetical protein 0.0062 0.0275 0.0293
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Trypanosoma cruzi major cysteine proteinase, putative 0.009 0.0442 0.0469
Echinococcus granulosus histone lysine methyltransferase setb 0.0065 0.0294 0.0313
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0017 0.0019 0.0019
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0125 0.0122
Onchocerca volvulus 0.0017 0.0019 0.002
Schistosoma mansoni hypothetical protein 0.1246 0.7104 0.7559
Schistosoma mansoni RAR-like nuclear receptor 0.0136 0.0704 0.0749
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0362 0.0374
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0136 0.0704 0.0704
Plasmodium vivax ferrodoxin reductase, putative 0.0017 0.002 0.01
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0039 0.0143 0.0143
Echinococcus multilocularis Polycystic kidney disease protein 0.0039 0.0144 0.0144
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0017 0.002 0.0021
Plasmodium falciparum NAD(P)H-dependent glutamate synthase, putative 0.0017 0.002 0.0168
Schistosoma mansoni regulator of G protein signaling 0.0077 0.0362 0.0385
Schistosoma mansoni disulfide oxidoreductase 0.0017 0.002 0.0021
Loa Loa (eye worm) hypothetical protein 0.0136 0.0704 0.0749
Schistosoma mansoni biogenic amine receptor 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0064 0.029 0.0308
Trypanosoma cruzi 2,4-dienoyl-coa reductase-like protein, putative 0.0017 0.002 0.002
Brugia malayi G protein-coupled receptor F59B2.13 0.0017 0.0019 0.002
Echinococcus granulosus Na channel amiloride sensitive 0.0134 0.0692 0.0736
Brugia malayi Serotonin receptor 0.0017 0.0019 0.002
Entamoeba histolytica acetyltransferase, GNAT family 0.004 0.0151 0.015
Schistosoma mansoni neuropeptide receptor 0.0017 0.0019 0.002
Loa Loa (eye worm) AGC/PKG protein kinase 0.0014 0.0003 0.0003
Brugia malayi Hypothetical 29.7 kDa protein C05D11.5 in chromosome III 0.0025 0.0064 0.0068
Mycobacterium ulcerans phenyloxazoline synthase MbtB 0.0021 0.004 0.0129
Trypanosoma brucei DNA polymerase kappa, putative 0.0026 0.0073 0.0067
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0017 0.0017 0.0017
Echinococcus multilocularis pyruvate kinase 0.0033 0.0109 0.0109
Onchocerca volvulus 0.003 0.0094 0.0101
Brugia malayi CXXC zinc finger family protein 0.0176 0.0934 0.0994
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0362 0.0374
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0012 0.0013
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0094 0.009
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0017 0.0019 0.0019
Brugia malayi Latrophilin receptor protein 2 0.0017 0.0017 0.0018
Brugia malayi AMP-binding enzyme family protein 0.0021 0.004 0.0043
Brugia malayi jmjC domain containing protein 0.0035 0.0124 0.0132
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0142 0.014
Brugia malayi hypothetical protein 0.0064 0.029 0.0308
Echinococcus granulosus CCR4 NOT transcription complex subunit 6 0.0016 0.0012 0.0013
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0125 0.0122
Echinococcus granulosus hypothetical protein 0.0017 0.0019 0.002
Trypanosoma cruzi Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0012 0.0012
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0136 0.0704 0.0704
Entamoeba histolytica glycosyl hydrolase, family 31 protein 0.0035 0.0125 0.0122
Loa Loa (eye worm) hypothetical protein 0.0134 0.0692 0.0736
Toxoplasma gondii PHD-finger domain-containing protein 0.0062 0.0275 0.1455
Trypanosoma cruzi mitochondrial protein 99, putative 0.0016 0.0012 0.0012
Brugia malayi G protein-coupled receptor 0.0017 0.0019 0.002
Brugia malayi hypothetical protein 0.0308 0.1696 0.1805
Echinococcus granulosus GPCR family 2 0.0017 0.0017 0.0018
Echinococcus granulosus pyruvate kinase 0.0017 0.0017 0.0018
Trypanosoma brucei NADH dehydrogenase 0.0017 0.002 0.0011
Trypanosoma brucei Inositol phosphosphingolipids phospholipase C 0.0016 0.0012 0.0002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0144 0.0749 0.0797
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0019 0.0019
Schistosoma mansoni hypothetical protein 0.002 0.0036 0.0039
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0265 0.1446 0.1538
Echinococcus granulosus muscleblind protein 0.0108 0.0546 0.0581
Schistosoma mansoni hypothetical protein 0.0134 0.0692 0.0736
Brugia malayi TAR-binding protein 0.0583 0.3282 0.3492
Leishmania major DNA polymerase kappa, putative 0.0038 0.0142 0.015
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0136 0.0704 0.0749
Brugia malayi nuclear hormone receptor family member nhr-6 0.0064 0.029 0.0308
Loa Loa (eye worm) hypothetical protein 0.0136 0.0704 0.0749
Leishmania major hypothetical protein, conserved 0.0016 0.0012 0.0012
Mycobacterium leprae Probable pyruvate kinase PykA 0.0033 0.0109 0.0337
Echinococcus granulosus dnaJ subfamily B 0.1246 0.7104 0.7559
Echinococcus granulosus dna polymerase eta 0.0038 0.0142 0.0151
Schistosoma mansoni voltage-gated potassium channel 0.0022 0.0048 0.0051
Trypanosoma cruzi ATP-dependent DEAD/H DNA helicase recQ, putative 0.0033 0.0113 0.0119
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.0057 0.0247 0.0247
Plasmodium falciparum endonuclease/exonuclease/phosphatase family protein, putative 0.0016 0.0012 0.0087
Echinococcus granulosus cathepsin l cysteine peptidase 0.003 0.0094 0.0101
Brugia malayi jmjC domain containing protein 0.0259 0.1416 0.1506
Loa Loa (eye worm) pyruvate kinase 0.0033 0.0109 0.0116
Schistosoma mansoni regulator of G protein signaling 3 rgs3 0.0077 0.0362 0.0385
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0385
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Trypanosoma cruzi hypothetical protein, conserved 0.0035 0.0125 0.0132
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0136 0.0704 0.0749
Loa Loa (eye worm) hypothetical protein 0.0216 0.1165 0.124
Echinococcus multilocularis serotonin receptor 0.0017 0.0019 0.0019
Plasmodium falciparum cysteine repeat modular protein 1 0.0017 0.0018 0.0148
Loa Loa (eye worm) hypothetical protein 0.002 0.0037 0.0039
Toxoplasma gondii endonuclease/exonuclease/phosphatase family protein 0.0016 0.0012 0.0047
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD2 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0071 0.0329 0.1193
Echinococcus granulosus tachykinin peptides receptor 99D 0.0017 0.0019 0.002
Echinococcus granulosus neuropeptide receptor 0.0017 0.0019 0.002
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0018
Loa Loa (eye worm) glycosyl hydrolase family 31 protein 0.016 0.0842 0.0895
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.002 0.0037 0.0029
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0144 0.0749 0.0797
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0017 0.0019 0.002
Echinococcus granulosus PHD finger protein rhinoceros 0.0062 0.0275 0.0293
Mycobacterium ulcerans bifunctional enzyme MbtA: salicyl-AMP ligase (SAL-AMP ligase) + salicyl-S-ACP synthetase 0.0021 0.004 0.0129
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0362 0.0374
Echinococcus granulosus serine:threonine protein kinase PLK1 0.1644 0.9398 1
Echinococcus granulosus NADPH:adrenodoxin oxidoreductase 0.0017 0.002 0.0021
Onchocerca volvulus 0.0028 0.008 0.0085
Echinococcus granulosus cysteine protease 0.0016 0.001 0.0011
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0012 0.0013
Trypanosoma brucei ISWI complex protein 0.0018 0.0027 0.0018
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0142 0.014
Echinococcus granulosus alpha 1A adrenergic receptor 0.0017 0.0019 0.002
Schistosoma mansoni thyroid hormone receptor 0.0136 0.0704 0.0749
Brugia malayi G-protein coupled receptor 0.0017 0.0019 0.002
Trypanosoma cruzi NADH dehydrogenase, putative 0.0017 0.002 0.002
Echinococcus multilocularis g-protein coupled receptor 0.0017 0.0019 0.0019
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.1446 0.1529
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0329 0.0339
Echinococcus multilocularis sodium channel nonvoltage gated 1 alpha 0.0134 0.0692 0.0692
Schistosoma mansoni lipoxygenase 0.0232 0.1258 0.1338
Mycobacterium ulcerans fatty-acid-CoA ligase 0.0071 0.0329 0.1959
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0136 0.0704 0.0749
Schistosoma mansoni voltage-gated potassium channel 0.0077 0.0363 0.0386
Brugia malayi Doublecortin family protein 0.0039 0.0144 0.0153
Onchocerca volvulus Putative neutral sphingomyelinase 0.0016 0.0012 0.0013
Brugia malayi Pre-SET motif family protein 0.0429 0.2394 0.2547
Brugia malayi hypothetical protein 0.0034 0.0117 0.0125
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0024 0.0057 0.0057
Leishmania major cysteine peptidase A (CPA) 0.003 0.0094 0.01
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.001 0.0011
Echinococcus multilocularis GPCR, family 2 0.0017 0.0017 0.0017
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0012 0.0013
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0065 0.0294 0.0313
Trichomonas vaginalis skeletal muscle/kidney enriched inositol 5-phosphatase, putative 0.0016 0.0012 0.0002
Loa Loa (eye worm) ctsf protein 0.003 0.0094 0.0101
Brugia malayi Egg laying defective protein 4 0.0014 0.0003 0.0003
Plasmodium vivax FAD-linked sulfhydryl oxidase ERV1, putative 0.0034 0.0114 0.1046
Mycobacterium tuberculosis Peptide synthetase MbtF (peptide synthase) 0.0021 0.004 0.0107
Plasmodium vivax endonuclease/exonuclease/phosphatase domain containing protein 0.0016 0.0012 0.0018
Toxoplasma gondii PHD-finger domain-containing protein 0.002 0.0036 0.0178
Brugia malayi ImpB/MucB/SamB family protein 0.0038 0.0142 0.0151
Leishmania major cytochrome p450-like protein 0.0018 0.0026 0.0026
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0385
Echinococcus multilocularis somatostatin receptor 0.0017 0.0019 0.0019
Trypanosoma brucei acetyl-CoA synthetase, putative 0.0021 0.004 0.0032
Schistosoma mansoni inositol transporter 0.0077 0.0367 0.039
Leishmania major hypothetical protein, conserved 0.0017 0.0018 0.0018
Loa Loa (eye worm) nuclear hormone receptor 0.0064 0.029 0.0308
Loa Loa (eye worm) glutathione reductase 0.0188 0.1003 0.1067
Onchocerca volvulus Pyruvate kinase homolog 0.0033 0.0109 0.0116
Plasmodium vivax acetyl-CoA synthetase, putative 0.0021 0.004 0.0304
Schistosoma mansoni hyperpolarization activated cyclic nucleotide-gated potassium channel 0.0016 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.002 0.0037 0.0039
Echinococcus multilocularis synaptojanin 1 0.0016 0.0012 0.0012
Echinococcus granulosus regulator of G protein signaling 3 0.0077 0.0362 0.0385
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0232 0.1258 0.1338
Echinococcus multilocularis JmjC domain containing protein 4 0.0035 0.0124 0.0124
Toxoplasma gondii exonuclease III APE 0.0079 0.0374 0.1979
Brugia malayi Dopamine receptor 0.0017 0.0019 0.002
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0129
Echinococcus multilocularis pyruvate kinase 0.0017 0.0017 0.0017
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0017 0.0019 0.0019
Echinococcus multilocularis pyruvate kinase 0.0017 0.0017 0.0017
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0017 0.002 0.0011
Loa Loa (eye worm) G-protein coupled receptor 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0225 0.024
Leishmania major 4-coumarate:coa ligase-like protein 0.0071 0.0329 0.0349
Onchocerca volvulus 0.0039 0.0144 0.0153
Plasmodium vivax vivapain-2 0.003 0.0094 0.085
Trypanosoma cruzi cysteine peptidase, putative 0.0115 0.0584 0.062
Trypanosoma cruzi polo-like protein kinase, putative 0.1644 0.9398 1
Loa Loa (eye worm) hypothetical protein 0.0064 0.029 0.0308
Schistosoma mansoni axis inhibition protein axin 0.0077 0.0362 0.0385
Loa Loa (eye worm) hypothetical protein 0.0249 0.1358 0.1445
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0065 0.0296 0.0314
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0094 0.009
Brugia malayi Regulator of G protein signaling domain containing protein 0.0077 0.0362 0.0385
Trichomonas vaginalis voltage and ligand gated potassium channel, putative 0.0016 0.0012 0.0002
Giardia lamblia Sgs1 DNA helicase, putative 0.0026 0.0069 0.0061
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase family protein 0.0017 0.002 0.0021
Schistosoma mansoni hypothetical protein 0.0036 0.0129 0.0137
Echinococcus granulosus JmjC domain containing protein 4 0.0035 0.0124 0.0132
Plasmodium falciparum cysteine proteinase falcipain 2b 0.003 0.0094 0.0913
Loa Loa (eye worm) glutaminase 0.029 0.1595 0.1697
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Echinococcus granulosus FMRFamide activated amiloride sensitive sodium 0.0134 0.0692 0.0736
Echinococcus multilocularis pyruvate kinase 0.0033 0.0109 0.0109
Mycobacterium ulcerans glutaminase 0.029 0.1595 1
Echinococcus multilocularis g protein coupled receptor 0.0017 0.0019 0.0019
Loa Loa (eye worm) hypothetical protein 0.0035 0.0124 0.0132
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.001 0.001
Schistosoma mansoni dihydrolipoamide dehydrogenase 0.0065 0.0296 0.0315
Schistosoma mansoni glutamate synthase 0.0017 0.002 0.0021
Giardia lamblia Histone acetyltransferase GCN5 0.004 0.0151 0.0148
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0025 0.0067 0.0061
Loa Loa (eye worm) hypothetical protein 0.0077 0.0362 0.0385
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.001 0.0011
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0012 0.0013
Plasmodium vivax hypothetical protein, conserved 0.0062 0.0275 0.2672
Echinococcus multilocularis dihydropyrimidine dehydrogenase (NADP+) 0.0017 0.002 0.002
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.0046 0.0185 0.0197
Entamoeba histolytica hypothetical protein 0.0039 0.0143 0.0141
Brugia malayi hypothetical protein 0.0062 0.0278 0.0295
Onchocerca volvulus 0.0027 0.0077 0.0082
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0144 0.0144
Trypanosoma cruzi cytochrome P450, putative 0.0018 0.0026 0.0026
Trypanosoma brucei DNA polymerase IV, putative 0.0038 0.0142 0.014
Entamoeba histolytica cysteine proteinase, putative 0.002 0.0037 0.0029
Entamoeba histolytica hypothetical protein 0.0039 0.0143 0.0141
Trypanosoma cruzi NADPH:adrenodoxin oxidoreductase, mitochondrial, putative 0.0017 0.002 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0053 0.0225 0.024
Brugia malayi Dopamine receptor protein 2 0.0017 0.0019 0.002
Entamoeba histolytica acyl-CoA synthetase, putative 0.0071 0.0329 0.0339
Echinococcus granulosus microtubule associated protein 2 0.1383 0.7898 0.8404
Leishmania major cathepsin L-like protease 0.0115 0.0584 0.062
Leishmania major trypanothione reductase 0.0188 0.1003 0.1066
Loa Loa (eye worm) hypothetical protein 0.0017 0.0018 0.0019
Brugia malayi Degenerin mec-4 0.0134 0.0692 0.0736
Brugia malayi hypothetical protein 0.0039 0.0143 0.0152
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0136 0.0704 0.0749
Loa Loa (eye worm) degenerin unc-8 0.0134 0.0692 0.0736
Trypanosoma brucei 2,4-dienoyl-coa reductase-like protein 0.0017 0.002 0.0011
Leishmania major inositol/phosphatidylinositol phosphatase, putative 0.0016 0.0012 0.0012
Echinococcus granulosus terminal deoxycytidyl transferase rev1 0.0038 0.0142 0.0151
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Trichomonas vaginalis DNA helicase recq1, putative 0.0063 0.0281 0.0289
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0136 0.0704 0.0704
Toxoplasma gondii pyruvate kinase PyKII 0.0017 0.0017 0.0075
Echinococcus multilocularis lipoxygenase domain containing protein 0.0039 0.0144 0.0144
Echinococcus multilocularis geminin 0.1019 0.5797 0.5797
Trypanosoma cruzi NADH dehydrogenase, putative 0.0017 0.002 0.002
Trichomonas vaginalis conserved hypothetical protein 0.0077 0.0362 0.0374
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0072 0.0334 0.0356
Echinococcus granulosus dna polymerase kappa 0.0038 0.0142 0.0151
Leishmania major apurinic/apyrimidinic endonuclease-redox protein 0.0079 0.0374 0.0397
Brugia malayi cathepsin L-like precursor 0.002 0.0037 0.0039
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0012 0.0002
Schistosoma mansoni ocrl type II inositol 5-phosphatase 0.0016 0.0012 0.0013
Echinococcus multilocularis NADPH:adrenodoxin oxidoreductase 0.0017 0.002 0.002
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0017 0.0019 0.002
Echinococcus granulosus tumor protein p63 0.0189 0.1011 0.1076
Echinococcus granulosus peptide allatostatin:somatostatin 0.0017 0.0019 0.002
Trichomonas vaginalis disulfide oxidoreductase, putative 0.0017 0.002 0.0011
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.0064 0.029 0.0308
Echinococcus multilocularis serotonin receptor 0.0017 0.0019 0.0019
Mycobacterium ulcerans long-chain-fatty-acid--CoA ligase 0.0021 0.004 0.0129
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0136 0.0704 0.0749
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0188 0.1003 0.3735
Trichomonas vaginalis conserved hypothetical protein 0.004 0.015 0.0149
Schistosoma mansoni hypothetical protein 0.0134 0.0692 0.0736
Echinococcus multilocularis DNA (apurinic or apyrimidinic site) lyase 0.0079 0.0374 0.0374
Trypanosoma cruzi pyruvate kinase 2, putative 0.0033 0.0109 0.0115
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0136 0.0704 0.0749
Brugia malayi hypothetical protein 0.0017 0.0019 0.002
Echinococcus granulosus protein vprbp 0.0134 0.0692 0.0736
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Giardia lamblia Glutamate synthase 0.0017 0.002 0.0009
Schistosoma mansoni chromodomain helicase DNA binding protein 0.0017 0.0018 0.002
Trypanosoma cruzi acetyl-CoA synthetase, putative 0.0021 0.004 0.0042
Leishmania major DNA polymerase kappa, putative,DNA polymerase IV, putative 0.0038 0.0142 0.015
Mycobacterium tuberculosis Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate 0.0017 0.002 0.0031
Plasmodium vivax ataxin-2 like protein, putative 0.0053 0.0225 0.2166
Schistosoma mansoni microtubule-associated protein tau 0.1383 0.7898 0.8404
Schistosoma mansoni hypothetical protein 0.0017 0.0017 0.0018
Plasmodium falciparum carbon catabolite repressor protein 4, putative 0.0016 0.0012 0.0087
Echinococcus granulosus acetyl coenzyme A synthetase cytoplasmic 0.0021 0.004 0.0043
Schistosoma mansoni zinc finger protein 0.0064 0.029 0.0308
Brugia malayi putative neuropeptide receptor 0.0017 0.0019 0.002
Brugia malayi latrophilin 2 splice variant baaae 0.0036 0.0129 0.0137
Entamoeba histolytica deoxycytidyl transferase, putative 0.0038 0.0142 0.014
Trypanosoma cruzi DNA polymerase kappa, putative 0.0038 0.0142 0.015
Schistosoma mansoni regulator of G protein signaling 17 19 20 (rgs17 19 20) 0.0077 0.0362 0.0385
Onchocerca volvulus 0.002 0.0037 0.0039
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0142 0.014
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0065 0.0296 0.0314
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.019 0.0192
Trypanosoma cruzi PAB1-binding protein , putative 0.0053 0.0225 0.0239
Schistosoma mansoni alpha glucosidase 0.0035 0.0125 0.0133
Mycobacterium ulcerans flavoprotein disulfide reductase 0.0065 0.0296 0.175
Trichomonas vaginalis conserved hypothetical protein 0.004 0.015 0.0149
Trichomonas vaginalis alpha-glucosidase, putative 0.0035 0.0125 0.0122
Brugia malayi regulator of G-protein signaling egl-10 0.0077 0.0362 0.0385
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Brugia malayi G-protein coupled receptor 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0062 0.0277 0.0295
Loa Loa (eye worm) hypothetical protein 0.0095 0.0467 0.0497
Echinococcus granulosus hyperpolarization activated cyclic 0.0016 0.0012 0.0012
Leishmania major alpha glucosidase II subunit, putative 0.0035 0.0125 0.0132
Loa Loa (eye worm) PLK/PLK1 protein kinase 0.1644 0.9398 1
Echinococcus granulosus dihydropyrimidine dehydrogenase NADP 0.0017 0.002 0.0021
Loa Loa (eye worm) CHromoDomain protein family member 0.0017 0.0018 0.002
Echinococcus multilocularis PHD finger protein rhinoceros 0.0062 0.0275 0.0275
Schistosoma mansoni tar DNA-binding protein 0.0583 0.3282 0.3492
Schistosoma mansoni biogenic amine (5HT) receptor 0.0017 0.0019 0.002
Plasmodium vivax AP endonuclease (DNA-[apurinic or apyrimidinic site] lyase), putative 0.0079 0.0374 0.366
Mycobacterium tuberculosis Probable membrane NADH dehydrogenase NdhA 0.0428 0.239 0.8962
Echinococcus multilocularis dna polymerase eta 0.0038 0.0142 0.0142
Brugia malayi Cathepsin L-like cysteine proteinase 0.002 0.0037 0.0039
Loa Loa (eye worm) endonuclease/Exonuclease/phosphatase 0.0016 0.0012 0.0013
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0136 0.0704 0.0749
Trypanosoma brucei hypothetical protein, conserved 0.0017 0.002 0.0011
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0265 0.1446 0.1538
Entamoeba histolytica recQ family helicase, putative 0.0033 0.0113 0.011
Loa Loa (eye worm) hypothetical protein 0.0072 0.0334 0.0356
Entamoeba histolytica sphingomyelinase C precursor, putative 0.0016 0.0012 0.0002
Echinococcus granulosus orexin receptor type 2 0.0017 0.0019 0.002
Mycobacterium leprae conserved hypothetical protein 0.0025 0.0064 0.0167
Onchocerca volvulus 0.0017 0.0019 0.002
Loa Loa (eye worm) pyruvate kinase-PB 0.0023 0.0052 0.0055
Loa Loa (eye worm) hypothetical protein 0.0016 0.0012 0.0013
Entamoeba histolytica hypothetical protein 0.0077 0.0362 0.0374
Echinococcus multilocularis beta adrenergic receptor kinase 0.0082 0.0392 0.0392
Echinococcus multilocularis regulator of G protein signaling 7 0.0077 0.0362 0.0362
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0129
Plasmodium falciparum exodeoxyribonuclease III, putative 0.0016 0.0012 0.0087
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0065 0.0296 0.0314
Toxoplasma gondii transporter, solute:sodium symporter (SSS) family protein 0.0077 0.0367 0.1942
Loa Loa (eye worm) hypothetical protein 0.0062 0.0278 0.0295
Loa Loa (eye worm) TAR-binding protein 0.0583 0.3282 0.3492
Toxoplasma gondii non-proton pumping type-II NADH dehydrogenase I 0.0017 0.002 0.009
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Loa Loa (eye worm) hypothetical protein 0.0026 0.0069 0.0074
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Loa Loa (eye worm) hypothetical protein 0.0023 0.0052 0.0055
Echinococcus multilocularis allatostatin A receptor 0.0017 0.0019 0.0019
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0142 0.014
Echinococcus granulosus cathepsin L cysteine proteinase 0.003 0.0094 0.0101
Trypanosoma brucei dihydrolipoamide dehydrogenase 0.0065 0.0296 0.0304
Brugia malayi CHD4 protein 0.0017 0.0018 0.002
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Brugia malayi Calcitonin receptor-like protein seb-1 0.0053 0.0225 0.024
Plasmodium falciparum thioredoxin reductase 0.0188 0.1003 1
Schistosoma mansoni blooms syndrome DNA helicase 0.0049 0.0205 0.0218
Schistosoma mansoni hypothetical protein 0.0017 0.0019 0.002
Loa Loa (eye worm) flap endonuclease-1 0.0018 0.0023 0.0024
Giardia lamblia Glycerol-3-phosphate dehydrogenase 0.0017 0.002 0.0009
Entamoeba histolytica endonuclease/exonuclease/phosphatase family protein 0.0016 0.0012 0.0002
Plasmodium vivax thioredoxin reductase, putative 0.0188 0.1003 1
Schistosoma mansoni phd/f-box containing protein 0.0035 0.0124 0.0132
Brugia malayi Kringle domain containing protein 0.0017 0.0018 0.0019
Mycobacterium ulcerans short-chain type dehydrogenase/reductase 0.0043 0.0167 0.0936
Mycobacterium ulcerans acyl-CoA synthetase 0.0021 0.004 0.0129
Toxoplasma gondii histone lysine acetyltransferase GCN5-B 0.0044 0.0172 0.0903
Trichomonas vaginalis regulator of G protein signaling 5, rgs5, putative 0.0077 0.0362 0.0374
Toxoplasma gondii pyruvate kinase PyK1 0.0033 0.0109 0.0566
Echinococcus multilocularis sodium coupled monocarboxylate transporter 1 0.0077 0.0367 0.0367
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD8 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.0021 0.004 0.0107
Trypanosoma cruzi 2,4-dienoyl-coa reductase fadh1, putative 0.0017 0.002 0.002
Onchocerca volvulus 0.0021 0.004 0.0043
Trypanosoma cruzi cysteine proteinase, putative 0.0016 0.001 0.001
Trichomonas vaginalis ap endonuclease, putative 0.0079 0.0374 0.0387
Entamoeba histolytica cysteine proteinase, putative 0.003 0.0094 0.009
Brugia malayi Cathepsin L-like precursor 0.002 0.0037 0.0039
Mycobacterium tuberculosis Probable nitrite reductase [NAD(P)H] large subunit [FAD flavoprotein] NirB 0.0428 0.239 0.8962
Loa Loa (eye worm) AGC/GRK/GRK protein kinase 0.0082 0.0392 0.0418
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0017 0.0019 0.002
Onchocerca volvulus 0.0017 0.0019 0.002
Trypanosoma cruzi Inositol phosphosphingolipids phospholipase C 0.0016 0.0012 0.0012
Onchocerca volvulus Bile acid receptor homolog 0.0136 0.0704 0.0749
Loa Loa (eye worm) hypothetical protein 0.0064 0.029 0.0308
Loa Loa (eye worm) hypothetical protein 0.0033 0.0109 0.0116
Schistosoma mansoni aryl hydrocarbon receptor 0.0033 0.0111 0.0118
Entamoeba histolytica long-chain-fatty-acid--CoA ligase, putative 0.0021 0.004 0.0032
Mycobacterium tuberculosis Probable reductase 0.0428 0.239 0.8962
Onchocerca volvulus 0.0016 0.0012 0.0013
Leishmania major endonuclease/exonuclease protein-like protein 0.0016 0.0012 0.0012
Loa Loa (eye worm) hypothetical protein 0.0064 0.029 0.0308
Echinococcus multilocularis cysteine protease 0.003 0.0094 0.0094
Leishmania major cathepsin L-like protease 0.003 0.0094 0.01
Brugia malayi Endonuclease/Exonuclease/phosphatase family protein 0.0016 0.0012 0.0013
Trichomonas vaginalis CAMK family protein kinase 0.1644 0.9398 1
Schistosoma mansoni synaptojanin 0.0016 0.0012 0.0013
Plasmodium vivax pyruvate kinase, putative 0.0033 0.0109 0.0996
Brugia malayi nuclear hormone receptor family member odr-7 0.0064 0.029 0.0308
Schistosoma mansoni growth hormone secretagogue receptor 0.0017 0.0019 0.002
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.003 0.0094 0.009
Toxoplasma gondii PHD-finger domain-containing protein 0.0062 0.0275 0.1455
Loa Loa (eye worm) hypothetical protein 0.003 0.0094 0.01
Echinococcus granulosus cGMP dependent protein kinase 1 0.0014 0.0003 0.0003
Toxoplasma gondii endonuclease IV APN 0.0095 0.0467 0.248
Brugia malayi hypothetical protein 0.0017 0.0019 0.002
Toxoplasma gondii NADPH-glutathione reductase 0.0065 0.0296 0.1562
Trichomonas vaginalis CAMK family protein kinase 0.1644 0.9398 1
Echinococcus multilocularis peregrin 0.0065 0.0296 0.0296
Echinococcus multilocularis jumonji domain containing protein 0.0086 0.0414 0.0414
Trypanosoma cruzi dihydrolipoamide dehydrogenase, putative 0.0065 0.0296 0.0314
Onchocerca volvulus Neuropeptide F receptor homolog 0.0017 0.0019 0.002
Trichomonas vaginalis pyruvate kinase, putative 0.0033 0.0109 0.0105
Echinococcus granulosus cGMP dependent protein kinase 0.0014 0.0003 0.0003
Schistosoma mansoni hypothetical protein 0.0134 0.0692 0.0736
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.1446 0.1529
Mycobacterium tuberculosis Probable fatty-acid-CoA ligase FadD35 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase) 0.005 0.0209 0.0742
Plasmodium falciparum ATP-dependent DNA helicase Q1 0.0026 0.0069 0.0662
Trichomonas vaginalis conserved hypothetical protein 0.004 0.015 0.0149
Schistosoma mansoni carbon catabolite repressor protein 0.0016 0.0012 0.0013
Leishmania major cathepsin L-like protease 0.0115 0.0584 0.062
Trypanosoma brucei Endonuclease/Exonuclease/phosphatase family, putative 0.0016 0.0012 0.0002
Brugia malayi hypothetical protein 0.0053 0.0225 0.024
Trichomonas vaginalis conserved hypothetical protein 0.0028 0.0084 0.0079
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0017 0.0019 0.002
Plasmodium vivax apurinic/apyrimidinic endonuclease Apn1, putative 0.0095 0.0467 0.4606
Schistosoma mansoni serine/threonine protein kinase 0.0082 0.0392 0.0418
Echinococcus granulosus high affinity choline transporter 1 0.0702 0.3966 0.422
Trypanosoma cruzi pyridine nucleotide-disulphide oxidoreductase, putative 0.0017 0.002 0.002
Echinococcus multilocularis flap endonuclease 1 0.0018 0.0023 0.0023
Loa Loa (eye worm) jmjC domain-containing protein 0.0127 0.0653 0.0695
Loa Loa (eye worm) exodeoxyribonuclease III family protein 0.0079 0.0374 0.0397
Loa Loa (eye worm) hypothetical protein 0.0017 0.0019 0.002
Trichomonas vaginalis chromodomain helicase DNA binding protein, putative 0.0047 0.019 0.0192
Schistosoma mansoni amine GPCR 0.0017 0.0019 0.002
Entamoeba histolytica acyl-coA synthetase, putative 0.0071 0.0329 0.0339
Loa Loa (eye worm) hypothetical protein 0.0064 0.029 0.0308
Brugia malayi hypothetical protein 0.0017 0.0019 0.002
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0016 0.001 0.0011
Trypanosoma brucei DNA polymerase kappa, putative 0.0038 0.0142 0.014
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0115 0.0584 0.0611
Brugia malayi AMP-binding enzyme family protein 0.0021 0.004 0.0043
Leishmania major flap endonuclease-1 (FEN-1), putative 0.0018 0.0023 0.0023
Brugia malayi Cytochrome P450 family protein 0.0018 0.0026 0.0027
Echinococcus granulosus FAD linked sulfhydryl oxidase ALR 0.0034 0.0114 0.0121
Schistosoma mansoni nuclear receptor 0.0064 0.029 0.0308
Trypanosoma cruzi ERV/ALR sulfhydryl oxidase domain-containing protein 0.0034 0.0114 0.012
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0136 0.0704 0.0749
Brugia malayi Pyruvate kinase, M2 isozyme 0.0033 0.0109 0.0116
Echinococcus granulosus cyclic nucleotide gated cation channel 0.0016 0.0012 0.0012
Mycobacterium tuberculosis NAD(P)H quinone reductase LpdA 0.0476 0.2666 1
Echinococcus granulosus allatostatin A receptor 0.0017 0.0019 0.002
Plasmodium falciparum flap endonuclease 1 0.0018 0.0023 0.0194
Onchocerca volvulus Protein ultraspiracle homolog 0.0136 0.0704 0.0749
Schistosoma mansoni ap endonuclease 0.0079 0.0374 0.0397
Echinococcus multilocularis sodium:myo inositol cotransporter 0.0077 0.0367 0.0367
Loa Loa (eye worm) hypothetical protein 0.0039 0.0144 0.0153
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0136 0.0704 0.0749
Trypanosoma brucei trypanothione reductase 0.0188 0.1003 0.1058
Loa Loa (eye worm) AMP-binding enzyme family protein 0.0021 0.004 0.0043
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0016 0.001 0.0011
Echinococcus granulosus lysosomal alpha glucosidase 0.016 0.0842 0.0895
Mycobacterium tuberculosis Probable soluble pyridine nucleotide transhydrogenase SthA (STH) (NAD(P)(+) transhydrogenase [B-specific]) (nicotinamide nucleot 0.0065 0.0296 0.1069
Brugia malayi putative neuropeptide receptor NPR1 0.0017 0.0019 0.002
Schistosoma mansoni cellular tumor antigen P53 0.0028 0.008 0.0085
Loa Loa (eye worm) melatonin receptor type 1A 0.0017 0.0019 0.002
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.003 0.0094 0.009
Onchocerca volvulus 0.0092 0.0453 0.0482
Brugia malayi Nuclear hormone receptor-like 1 0.0072 0.0334 0.0356
Brugia malayi Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain containing protein 0.0048 0.0196 0.0209
Mycobacterium ulcerans long-chain-fatty-acid-CoA ligase 0.0071 0.0329 0.1959
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0017 0.0017 0.0017
Schistosoma mansoni amine GPCR 0.0017 0.0019 0.002
Echinococcus multilocularis apoptosis inducing factor 1 mitochondrial 0.0017 0.002 0.002
Trichomonas vaginalis glucosylceramidase, putative 0.0265 0.1446 0.1529

Activities

Activity type Activity value Assay description Source Reference
Potency (functional) 35.4813 uM PUBCHEM_BIOASSAY: qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID504404] ChEMBL. No reference

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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