Detailed information for compound 802179

Basic information

Technical information
  • TDR Targets ID: 802179
  • Name: N-(4-chlorophenyl)-2-[(4-methoxyphenyl)-[(4-m ethyl-2,6-dioxo-3H-pyrimidin-5-yl)sulfonyl]am ino]acetamide
  • MW: 478.906 | Formula: C20H19ClN4O6S
  • H donors: 3 H acceptors: 7 LogP: 3.32 Rotable bonds: 8
    Rule of 5 violations (Lipinski): 1
  • SMILES: COc1ccc(cc1)N(S(=O)(=O)c1c(C)nc(nc1O)O)CC(=O)Nc1ccc(cc1)Cl
  • InChi: 1S/C20H19ClN4O6S/c1-12-18(19(27)24-20(28)22-12)32(29,30)25(15-7-9-16(31-2)10-8-15)11-17(26)23-14-5-3-13(21)4-6-14/h3-10H,11H2,1-2H3,(H,23,26)(H2,22,24,27,28)
  • InChiKey: IZLVVMDSFKPZPM-UHFFFAOYSA-N  


Substructure search Similarity search

Network

Hover on a compound node to display the structore

Synonyms

  • N-(4-chlorophenyl)-2-[(2,4-diketo-6-methyl-1H-pyrimidin-5-yl)sulfonyl-(4-methoxyphenyl)amino]acetamide
  • N-(4-chlorophenyl)-2-[(4-methoxyphenyl)-[(4-methyl-2,6-dioxo-3H-pyrimidin-5-yl)sulfonyl]amino]ethanamide

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor E75 0.001 0.0023 0.0038
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0674 0.7766
Onchocerca volvulus 0.003 0.0268 0.0884
Loa Loa (eye worm) papain family cysteine protease containing protein 0.0016 0.01 0.0133
Echinococcus multilocularis lamin 0.0027 0.0237 0.0237
Brugia malayi hypothetical protein 0.0013 0.0062 0.0105
Brugia malayi Cathepsin L-like precursor 0.0016 0.01 0.017
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0017
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0165 0.0282
Mycobacterium tuberculosis Probable lipase LipD 0.0078 0.0868 0.0225
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0078 0.0868 0.1454
Brugia malayi nuclear receptor RXR 0.0011 0.0038 0.0064
Echinococcus multilocularis cpg binding protein 0.0031 0.0283 0.0283
Echinococcus granulosus basement membrane specific heparan sulfate 0.003 0.0275 0.0323
Schistosoma mansoni nuclear receptor nhr-48 0.001 0.0023 0.0055
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0064 0.0687 0.1663
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.0022 0.0165 0.0514
Echinococcus granulosus RUN 0.0019 0.0138 0.0162
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0022 0.0165 0.0282
Brugia malayi Dopamine receptor protein 1 0.0013 0.0062 0.0105
Schistosoma mansoni thyroid hormone receptor 0.0292 0.3527 0.8544
Echinococcus multilocularis orexin receptor type 2 0.0013 0.0062 0.0062
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0062 0.0062
Loa Loa (eye worm) latrophilin receptor protein 2 0.0048 0.0493 0.081
Schistosoma mansoni biogenic amine (5HT) receptor 0.0013 0.0062 0.015
Brugia malayi hypothetical protein 0.0019 0.0138 0.0235
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Loa Loa (eye worm) hypothetical protein 0.0016 0.01 0.0133
Onchocerca volvulus 0.0011 0.0032 0.0034
Loa Loa (eye worm) inositol-1 0.0076 0.0847 0.1417
Loa Loa (eye worm) hypothetical protein 0.0013 0.0054 0.0055
Brugia malayi latrophilin 2 splice variant baaae 0.0104 0.1187 0.2032
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0546 0.6288
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0022 0.0165 0.0195
Onchocerca volvulus 0.0016 0.01 0.0278
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.0013 0.0062 0.0068
Brugia malayi hypothetical protein 0.0016 0.0093 0.0158
Loa Loa (eye worm) CMGC/MAPK/ERK1 protein kinase 0.0052 0.0546 0.09
Trypanosoma cruzi mitogen-activated protein kinase 11, putative 0.0052 0.0546 0.6288
Echinococcus granulosus GPCR family 2 0.0048 0.0493 0.058
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0847 0.9756
Echinococcus granulosus g protein coupled receptor 0.0013 0.0062 0.0073
Brugia malayi G-protein coupled receptor 0.0013 0.0062 0.0105
Brugia malayi beta-lactamase family protein 0.0078 0.0868 0.1485
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0022 0.0165 0.0165
Schistosoma mansoni thyroid hormone receptor 0.0292 0.3527 0.8544
Loa Loa (eye worm) hypothetical protein 0.0011 0.0038 0.0027
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0202 0.2318
Onchocerca volvulus 0.003 0.0275 0.0909
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0268 0.0649
Loa Loa (eye worm) hypothetical protein 0.0022 0.0165 0.0246
Brugia malayi photoreceptor-specific nuclear receptor 0.0022 0.0165 0.0282
Loa Loa (eye worm) hypothetical protein 0.0078 0.0868 0.1454
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0868 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0205 0.2444 0.4163
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.027 0.3257 0.3832
Entamoeba histolytica myo-inositol monophosphatase, putative 0.0076 0.0847 0.2212
Schistosoma mansoni cathepsin F (C01 family) 0.0011 0.0032 0.0078
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0062 0.0073
Echinococcus granulosus intermediate filament protein 0.0027 0.0237 0.0279
Schistosoma mansoni hypothetical protein 0.011 0.1264 0.3061
Echinococcus multilocularis dro:myosuppressin receptor 0.0013 0.0062 0.0062
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0062 0.0073
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0062 0.0062
Echinococcus granulosus mitogen activated protein kinase 0.0052 0.0546 0.0642
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Toxoplasma gondii LsmAD domain-containing protein 0.0025 0.0202 0.1327
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.01 0.0259
Echinococcus granulosus nuclear receptor nhr 48 0.001 0.0023 0.0027
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.003 0.0275 0.0275
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Brugia malayi nuclear receptor subfamily 1, group D, member 1, putative 0.001 0.0023 0.0038
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Echinococcus granulosus cathepsin l1 0.0011 0.0032 0.0038
Trypanosoma cruzi major cysteine proteinase, putative 0.0049 0.0508 0.5844
Plasmodium falciparum cysteine proteinase falcipain 2b 0.0016 0.01 0.4929
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0062 0.0062
Plasmodium vivax ataxin-2 like protein, putative 0.0025 0.0202 0.2318
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0062 0.0062
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0062 0.0073
Giardia lamblia Fructose-bisphosphate aldolase 0.0316 0.3825 1
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0022 0.0165 0.0246
Echinococcus granulosus nuclear receptor subfamily 4 group A 0.001 0.0023 0.0027
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.003 0.0275 0.0469
Echinococcus multilocularis nuclear receptor subfamily 1 group D 0.0011 0.0038 0.0038
Brugia malayi follicle stimulating hormone receptor 0.0013 0.0062 0.0105
Brugia malayi Cathepsin L-like precursor 0.0016 0.01 0.017
Echinococcus granulosus cysteine protease 0.0008 0.0001 0.0001
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0062 0.015
Plasmodium vivax vivapain-2 0.0016 0.01 0.1143
Echinococcus multilocularis inositol monophosphatase 1 0.0076 0.0847 0.0847
Mycobacterium ulcerans fusion of enoyl-CoA hydratase, EchA21 and lipase, LipE 0.0078 0.0868 0.0219
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0028 0.0246 0.029
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0001
Schistosoma mansoni amine GPCR 0.0013 0.0062 0.015
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0062 0.0073
Echinococcus multilocularis sex peptide receptor 0.0013 0.0062 0.0062
Treponema pallidum fructose-bisphosphate aldolase 0.0316 0.3825 0.5
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0048 0.0493 0.0844
Echinococcus multilocularis serotonin receptor 0.0013 0.0062 0.0062
Plasmodium falciparum cysteine proteinase falcipain 2a 0.0016 0.01 0.4929
Loa Loa (eye worm) hypothetical protein 0.0019 0.0138 0.0199
Echinococcus multilocularis cysteine protease 0.0016 0.01 0.01
Onchocerca volvulus Cathepsin L homolog 0.0016 0.01 0.0278
Onchocerca volvulus 0.0013 0.0062 0.0141
Trypanosoma cruzi myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0847 0.9756
Schistosoma mansoni alpha-1 adrenergic receptor 0.0013 0.0062 0.015
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0062 0.015
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Echinococcus multilocularis G protein coupled receptor 139 0.0013 0.0062 0.0062
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.0013 0.0062 0.015
Schistosoma mansoni biogenic amine receptor 0.0013 0.0062 0.015
Brugia malayi Doublecortin family protein 0.0019 0.0138 0.0235
Trypanosoma cruzi mitogen activated protein kinase 2, putative 0.0052 0.0546 0.6288
Brugia malayi hypothetical protein 0.0013 0.0062 0.0105
Echinococcus granulosus thyrotropin releasing hormone receptor 0.0013 0.0062 0.0073
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Echinococcus multilocularis nuclear receptor subfamily 4 group A 0.001 0.0023 0.0023
Brugia malayi neuropeptide F receptor 0.0013 0.0062 0.0105
Brugia malayi Dopamine receptor 0.0013 0.0062 0.0105
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0038 0.0064
Brugia malayi MAP kinase sur-1 0.0052 0.0546 0.0934
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0022 0.0165 0.0165
Brugia malayi conserved hypotetical protein 0.001 0.0023 0.0038
Onchocerca volvulus Basement membrane proteoglycan homolog 0.003 0.0275 0.0909
Leishmania major cathepsin L-like protease 0.0063 0.0674 0.7478
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0165 0.0282
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0138 0.0162
Echinococcus multilocularis fmrfamide receptor 0.0013 0.0062 0.0062
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3825 1
Echinococcus multilocularis fmrfamide receptor 0.0013 0.0062 0.0062
Onchocerca volvulus 0.0013 0.0062 0.0141
Loa Loa (eye worm) transcription factor SMAD2 0.0122 0.1409 0.2384
Schistosoma mansoni opsin-like receptor 0.0013 0.0062 0.015
Brugia malayi hypothetical protein 0.0013 0.0062 0.0105
Trypanosoma cruzi cysteine peptidase, putative 0.0016 0.01 0.1143
Loa Loa (eye worm) hypothetical protein 0.0477 0.5839 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.0013 0.0062 0.0073
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.01 0.0259
Entamoeba histolytica hypothetical protein 0.011 0.1264 0.3303
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0062 0.0062
Plasmodium falciparum LCCL domain-containing protein 0.0019 0.0138 0.6821
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Echinococcus multilocularis basement membrane specific heparan sulfate 0.003 0.0275 0.0275
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0062 0.0073
Loa Loa (eye worm) TYRA-2 protein 0.0013 0.0062 0.0068
Loa Loa (eye worm) hypothetical protein 0.0022 0.0165 0.0246
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.0013 0.0062 0.0105
Echinococcus multilocularis neuropeptides capa receptor 0.0013 0.0062 0.0062
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0165 0.0165
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0062 0.015
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0152 0.1785 0.3056
Echinococcus granulosus neuropeptide Y receptor 0.0013 0.0062 0.0073
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.003 0.0275 0.0469
Loa Loa (eye worm) hypothetical protein 0.0022 0.0165 0.0246
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.0013 0.0062 0.015
Schistosoma mansoni neuropeptide receptor 0.0013 0.0062 0.015
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0546 0.1426
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Echinococcus granulosus neuropeptide FF receptor 2 0.0013 0.0062 0.0073
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.0013 0.0062 0.0073
Brugia malayi Papain family cysteine protease containing protein 0.0016 0.01 0.017
Brugia malayi Calcitonin receptor-like protein seb-1 0.0152 0.1785 0.3056
Schistosoma mansoni adenoreceptor 0.0013 0.0062 0.015
Loa Loa (eye worm) intermediate filament protein 0.0027 0.0237 0.037
Schistosoma mansoni hypothetical protein 0.0013 0.0062 0.015
Onchocerca volvulus 0.0019 0.0138 0.0415
Echinococcus multilocularis thyroid hormone receptor alpha 0.0292 0.3527 0.3527
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0062 0.015
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0022 0.0165 0.0282
Echinococcus multilocularis neuropeptide s receptor 0.0485 0.5935 0.5935
Echinococcus multilocularis cytoplasmic intermediate filament protein 0.0013 0.006 0.006
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0062 0.015
Brugia malayi G protein-coupled receptor 0.0013 0.0062 0.0105
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0013 0.0062 0.015
Schistosoma mansoni neuropeptide F-like receptor 0.0013 0.0062 0.015
Onchocerca volvulus 0.0016 0.01 0.0278
Plasmodium vivax SET domain protein, putative 0.003 0.0268 0.308
Echinococcus granulosus Ataxin 2 N terminaldomain containing protein 0.0011 0.0033 0.0039
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0165 0.0282
Echinococcus granulosus somatostatin receptor 0.0013 0.0062 0.0073
Trypanosoma cruzi hypothetical protein, conserved 0.0078 0.0868 1
Echinococcus multilocularis biogenic amine (5HT) receptor 0.0013 0.0062 0.0062
Loa Loa (eye worm) ctsf protein 0.0016 0.01 0.0133
Trichomonas vaginalis set domain proteins, putative 0.0233 0.2795 0.7306
Schistosoma mansoni coup transcription factor 0.0022 0.0165 0.0401
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0674 0.7766
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0194 0.2316 0.2316
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.003 0.0275 0.0275
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.01 0.0259
Brugia malayi Cathepsin L-like precursor 0.0016 0.01 0.017
Trypanosoma brucei protein kinase, putative 0.0052 0.0546 0.6288
Loa Loa (eye worm) DR-78 0.001 0.0023 0.0001
Brugia malayi Low-density lipoprotein receptor-related protein, putative 0.003 0.0275 0.0469
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0062 0.0073
Echinococcus granulosus arachidonate 5 lipoxygenase 0.0054 0.0574 0.0675
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Echinococcus granulosus neuropeptides capa receptor 0.0013 0.0062 0.0073
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0138 0.0138
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.0013 0.0062 0.0068
Brugia malayi Serotonin receptor 0.0013 0.0062 0.0105
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0674 0.7766
Leishmania major mitogen activated protein kinase, putative,map kinase, putative 0.0052 0.0546 0.581
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0001
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.027 0.3257 0.3257
Brugia malayi AKH receptor 0.0013 0.0062 0.0105
Brugia malayi Nuclear hormone receptor E75 0.001 0.0023 0.0038
Schistosoma mansoni nuclear receptor 0.001 0.0023 0.0055
Brugia malayi ecdysone receptor 0.001 0.0023 0.0038
Schistosoma mansoni hypothetical protein 0.0048 0.0493 0.1195
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0048 0.0493 0.058
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Echinococcus multilocularis low density lipoprotein receptor (ldl) 0.003 0.0275 0.0275
Echinococcus granulosus mitogen activated protein kinase 3 0.0052 0.0546 0.0642
Brugia malayi Cathepsin L-like precursor 0.0016 0.01 0.017
Brugia malayi nuclear hormone receptor 0.0022 0.0165 0.0282
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Onchocerca volvulus 0.0013 0.0062 0.0141
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.0013 0.0062 0.015
Echinococcus granulosus G protein coupled receptor 139 0.0013 0.0062 0.0073
Loa Loa (eye worm) MH2 domain-containing protein 0.0122 0.1409 0.2384
Schistosoma mansoni steroid hormone receptor ad4bp 0.0022 0.0165 0.0401
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0674 0.7766
Loa Loa (eye worm) hypothetical protein 0.0022 0.0165 0.0246
Onchocerca volvulus 0.0013 0.0062 0.0141
Onchocerca volvulus 0.0078 0.0868 0.3049
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3825 1
Echinococcus multilocularis GPCR, family 2 0.0048 0.0493 0.0493
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.01 0.01
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.0013 0.0062 0.0073
Schistosoma mansoni ecdysone-induced protein 78c (dr-78) 0.0011 0.0038 0.0092
Echinococcus granulosus lamin dm0 0.0027 0.0237 0.0279
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0022 0.0165 0.0165
Brugia malayi MH2 domain containing protein 0.0122 0.1409 0.2412
Echinococcus granulosus dro:myosuppressin receptor 0.0013 0.0062 0.0073
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Onchocerca volvulus 0.0013 0.0062 0.0141
Echinococcus multilocularis low density lipoprotein receptor protein 0.003 0.0275 0.0275
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0062 0.0062
Brugia malayi G-protein coupled receptor 0.0013 0.0062 0.0105
Onchocerca volvulus 0.0029 0.0262 0.0863
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.0013 0.0062 0.015
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.0013 0.0062 0.0068
Onchocerca volvulus 0.0013 0.0062 0.0141
Leishmania major myo-inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0847 0.9724
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0001
Echinococcus multilocularis neuropeptide Y receptor 0.0013 0.0062 0.0062
Echinococcus multilocularis g-protein coupled receptor 0.0013 0.0062 0.0062
Schistosoma mansoni amine GPCR 0.0013 0.0062 0.015
Entamoeba histolytica hypothetical protein 0.011 0.1264 0.3303
Onchocerca volvulus 0.003 0.0275 0.0909
Schistosoma mansoni polycystin 1-related 0.0019 0.0138 0.0334
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Trypanosoma brucei PAB1-binding protein , putative 0.0025 0.0202 0.2318
Brugia malayi putative neuropeptide receptor 0.0013 0.0062 0.0105
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0062 0.015
Echinococcus granulosus neuropeptide s receptor 0.0485 0.5935 0.6982
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0194 0.2316 0.2724
Toxoplasma gondii histone lysine methyltransferase SET1 0.0057 0.0604 0.6558
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0048 0.0493 0.058
Echinococcus multilocularis tachykinin peptides receptor 99D 0.0013 0.0062 0.0062
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0062 0.0062
Echinococcus granulosus inositol monophosphatase 1 0.0076 0.0847 0.0996
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.0847 0.2212
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Echinococcus multilocularis ecdysone induced protein 78C 0.0022 0.0165 0.0165
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0022 0.0165 0.0195
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0022 0.0165 0.0282
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0001
Onchocerca volvulus 0.0013 0.0062 0.0141
Onchocerca volvulus 0.0022 0.0165 0.0514
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Loa Loa (eye worm) hypothetical protein 0.0027 0.0237 0.037
Loa Loa (eye worm) melatonin receptor type 1A 0.0013 0.0062 0.0068
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0868 0.2267
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.003 0.0275 0.0666
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0022 0.0165 0.0195
Brugia malayi Cathepsin L-like precursor 0.0011 0.0032 0.0054
Brugia malayi Cathepsin L-like precursor 0.0011 0.0032 0.0054
Echinococcus granulosus Low density lipoprotein receptor class A cysteine rich 0.003 0.0275 0.0323
Echinococcus multilocularis cathepsin L 0.0008 0.0001 0.0001
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0868 0.2267
Schistosoma mansoni zinc finger protein 0.001 0.0023 0.0055
Mycobacterium tuberculosis Probable lipase LipE 0.0078 0.0868 0.0225
Onchocerca volvulus 0.0016 0.01 0.0278
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.0013 0.0062 0.0062
Mycobacterium leprae Probable fructose bisphosphate aldolase Fba 0.0154 0.1815 1
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Echinococcus multilocularis basement membrane specific heparan sulfate 0.003 0.0275 0.0275
Echinococcus granulosus cathepsin L cysteine protease 0.0008 0.0001 0.0001
Schistosoma mansoni amine GPCR 0.0013 0.0062 0.015
Onchocerca volvulus 0.0013 0.0062 0.0141
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Onchocerca volvulus 0.0013 0.0062 0.0141
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0674 0.7766
Brugia malayi hypothetical protein 0.0013 0.0062 0.0105
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Loa Loa (eye worm) steroid hormone receptor 0.0022 0.0165 0.0246
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0202 1
Brugia malayi cathepsin L-like precursor 0.0011 0.0032 0.0054
Brugia malayi hypothetical protein 0.0011 0.0038 0.0064
Echinococcus granulosus low density lipoprotein receptor ldl 0.003 0.0275 0.0323
Brugia malayi F/Y-rich N-terminus family protein 0.001 0.0021 0.0034
Onchocerca volvulus 0.0013 0.0062 0.0141
Echinococcus granulosus biogenic amine 5HT receptor 0.0013 0.0062 0.0073
Schistosoma mansoni hypothetical protein 0.0048 0.0493 0.1195
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0674 0.7766
Schistosoma mansoni hypothetical protein 0.003 0.0275 0.0666
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0013 0.0062 0.0062
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Brugia malayi ORL1-like opioid receptor 0.0013 0.0062 0.0105
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0023 0.0023
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0001 0.0002
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.003 0.0275 0.0434
Entamoeba histolytica hypothetical protein 0.011 0.1264 0.3303
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0022 0.0165 0.0401
Entamoeba histolytica cysteine proteinase, putative 0.0016 0.01 0.0259
Brugia malayi gonadotropin-releasing hormone receptor 2 0.0013 0.0062 0.0105
Schistosoma mansoni hypothetical protein 0.0011 0.0033 0.008
Onchocerca volvulus 0.0027 0.0237 0.0774
Echinococcus granulosus tachykinin peptides receptor 99D 0.0013 0.0062 0.0073
Onchocerca volvulus Bile acid receptor homolog 0.0022 0.0165 0.0514
Echinococcus granulosus cathepsin l cysteine peptidase 0.0016 0.01 0.0117
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0194 0.2316 0.5609
Echinococcus granulosus alpha 1A adrenergic receptor 0.0013 0.0062 0.0073
Echinococcus granulosus 7TM GPCR rhodopsin 0.0013 0.0062 0.0073
Schistosoma mansoni hypothetical protein 0.034 0.4128 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.01 0.01
Trichomonas vaginalis myo inositol monophosphatase, putative 0.0076 0.0847 0.2212
Mycobacterium ulcerans beta-lactamase 0.0078 0.0868 0.0219
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.0013 0.0062 0.0062
Brugia malayi Tachykinin-like peptides receptor 99D 0.0013 0.0062 0.0105
Schistosoma mansoni lamin 0.0027 0.0237 0.0575
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.0013 0.0062 0.0105
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0268 0.0649
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.001 0.0023 0.0023
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0674 0.7766
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.003 0.0275 0.0469
Onchocerca volvulus 0.003 0.0275 0.0909
Brugia malayi nuclear receptor NHR-88 0.0022 0.0165 0.0282
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3825 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.0013 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0022 0.0165 0.0282
Echinococcus granulosus Polycystic kidney disease protein 0.0019 0.0138 0.0162
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0674 0.7766
Schistosoma mansoni nuclear hormone receptor superfamily protein-related 0.001 0.0023 0.0055
Loa Loa (eye worm) hypothetical protein 0.0011 0.0038 0.0027
Schistosoma mansoni serine/threonine protein kinase 0.0052 0.0546 0.1323
Loa Loa (eye worm) hypothetical protein 0.0025 0.0202 0.0309
Onchocerca volvulus Cathepsin L homolog 0.0016 0.01 0.0278
Brugia malayi nuclear receptor NHR-67 0.001 0.0023 0.0038
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0022 0.0165 0.0195
Brugia malayi Cathepsin L-like precursor 0.0016 0.01 0.017
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.0013 0.0062 0.0068
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0674 0.7766
Trypanosoma cruzi cysteine peptidase, putative 0.0063 0.0674 0.7766
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0022 0.0165 0.0282
Echinococcus granulosus g-protein coupled receptor 0.0013 0.0062 0.0073
Loa Loa (eye worm) beta-lactamase 0.0078 0.0868 0.1454
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0062 0.015
Echinococcus granulosus survival motor neuron protein 1 0.0477 0.5839 0.6868
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0022 0.0165 0.0282
Echinococcus granulosus cathepsin L 0.0008 0.0001 0.0001
Echinococcus granulosus 7tm_1 domain containing protein 0.0013 0.0062 0.0073
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0194 0.2316 0.3965
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.003 0.0275 0.0469
Echinococcus granulosus 5'partial|Low density lipoprotein receptor class A cysteine rich 0.003 0.0275 0.0323
Brugia malayi Calcium binding EGF domain containing protein 0.003 0.0275 0.0469
Loa Loa (eye worm) hypothetical protein 0.003 0.0268 0.0422
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0194 0.2316 0.3943
Brugia malayi nuclear receptor RXR 0.001 0.0023 0.0038
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0022 0.0165 0.0246
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0868 0.2102
Echinococcus granulosus beta LACTamase domain containing family member 0.0078 0.0868 0.1021
Entamoeba histolytica hypothetical protein 0.011 0.1264 0.3303
Loa Loa (eye worm) Papain cysteine protease/cathepsin propeptide inhibitor-containing protein 0.0016 0.01 0.0133
Echinococcus multilocularis histone lysine N methyltransferase MLL3 0.001 0.0022 0.0022
Loa Loa (eye worm) cytoplasmic intermediate filament protein 0.0015 0.0079 0.0097
Schistosoma mansoni neuropeptide F-like receptor 0.0013 0.0062 0.015
Schistosoma mansoni neuropeptide receptor 0.0013 0.0062 0.015
Echinococcus granulosus cytoplasmic intermediate filament protein 0.0013 0.006 0.0071
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0022 0.0165 0.0165
Loa Loa (eye worm) G-protein coupled receptor 0.0013 0.0062 0.0068
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0268 0.2187
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0022 0.0165 0.0246
Onchocerca volvulus 0.0078 0.0868 0.3049
Schistosoma mansoni inositol monophosphatase 0.0076 0.0847 0.2051
Echinococcus granulosus g protein coupled receptor 0.0013 0.0062 0.0073
Schistosoma mansoni hepatocyte nuclear factor 4-alpha (hnf-4-alpha) 0.001 0.0023 0.0055
Brugia malayi hypothetical protein 0.0013 0.0062 0.0105
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0165 0.0195
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0023 0.0027
Schistosoma mansoni histamine h1 receptor 0.0013 0.0062 0.015
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.01 0.0259
Echinococcus multilocularis arachidonate 5 lipoxygenase 0.0054 0.0574 0.0574
Schistosoma mansoni opsin-like receptor 0.0013 0.0062 0.015
Loa Loa (eye worm) cysteine protease 0.0016 0.01 0.0133
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0032 0.0082
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Mycobacterium tuberculosis Conserved protein 0.0078 0.0868 0.0225
Echinococcus multilocularis Ataxin 2, N terminal,domain containing protein 0.0011 0.0033 0.0033
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0152 0.1785 0.303
Brugia malayi hypothetical protein 0.001 0.0023 0.0038
Echinococcus multilocularis neuropeptide receptor A26 0.0485 0.5935 0.5935
Schistosoma mansoni survival motor neuron protein 0.0097 0.1108 0.2683
Brugia malayi nuclear receptor NHR-88 0.001 0.0023 0.0038
Loa Loa (eye worm) nuclear hormone receptor-like 1 0.0011 0.0038 0.0027
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0048 0.0493 0.0493
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0048 0.0493 0.0493
Loa Loa (eye worm) neuropeptide F receptor 0.0013 0.0062 0.0068
Echinococcus multilocularis geminin 0.034 0.4128 0.4128
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0001
Brugia malayi hypothetical protein 0.0477 0.5839 1
Echinococcus granulosus allatostatin A receptor 0.0013 0.0062 0.0073
Echinococcus multilocularis nuclear receptor nhr 48 0.001 0.0023 0.0023
Onchocerca volvulus 0.0016 0.01 0.0278
Schistosoma mansoni opsin-like receptor 0.0013 0.0062 0.015
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0057 0.0607 0.6987
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0097 0.1108 0.1896
Echinococcus multilocularis alpha 1A adrenergic receptor 0.0013 0.0062 0.0062
Brugia malayi putative neuropeptide receptor NPR1 0.0013 0.0062 0.0105
Leishmania major cathepsin L-like protease 0.0063 0.0674 0.7478
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3825 1
Schistosoma mansoni amine GPCR 0.0013 0.0062 0.015
Loa Loa (eye worm) hypothetical protein 0.0022 0.0165 0.0246
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0499 0.6108 1
Leishmania major mitogen activated protein kinase 4, putative;with=GeneDB:LmxM19.1440 0.0052 0.0546 0.581
Schistosoma mansoni nuclear receptor 0.001 0.0023 0.0055
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0062 0.0062
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0546 0.1426
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0062 0.015
Loa Loa (eye worm) hypothetical protein 0.0078 0.0868 0.1454
Brugia malayi hypothetical protein 0.0013 0.0062 0.0105
Echinococcus multilocularis lipoxygenase domain containing protein 0.0019 0.0138 0.0138
Schistosoma mansoni loxhd1 0.0019 0.0138 0.0334
Schistosoma mansoni lamin 0.0027 0.0237 0.0575
Trypanosoma cruzi mitogen activated protein kinase 4, putative 0.0052 0.0546 0.6288
Echinococcus multilocularis allatostatin A receptor 0.0013 0.0062 0.0062
Brugia malayi nuclear hormone receptor family member nhr-6 0.001 0.0023 0.0038
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0268 0.0649
Trichomonas vaginalis esterase, putative 0.0078 0.0868 0.2267
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.011 0.1264 0.1264
Mycobacterium leprae conserved hypothetical protein 0.0078 0.0868 0.1132
Trypanosoma brucei inositol-1(or 4)-monophosphatase 1, putative 0.0076 0.0847 0.9756
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0062 0.0062
Loa Loa (eye worm) calcium binding EGF domain-containing protein 0.003 0.0275 0.0434
Onchocerca volvulus 0.0016 0.01 0.0278
Onchocerca volvulus Neuropeptide F receptor homolog 0.0013 0.0062 0.0141
Echinococcus multilocularis Polycystic kidney disease protein 0.0019 0.0138 0.0138
Schistosoma mansoni hypothetical protein 0.0097 0.1108 0.2683
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0022 0.0165 0.0246
Echinococcus granulosus sex peptide receptor 0.0013 0.0062 0.0073
Trichomonas vaginalis inositol monophosphatase, putative 0.0076 0.0847 0.2212
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.01 0.0259
Brugia malayi GnHR receptor homolog 0.0013 0.0062 0.0105
Mycobacterium ulcerans esterase/lipase LipP 0.0078 0.0868 0.0219
Entamoeba histolytica cysteine protease, putative 0.0016 0.01 0.0259
Onchocerca volvulus 0.0233 0.2795 1
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0546 0.1426
Loa Loa (eye worm) hypothetical protein 0.0011 0.0038 0.0027
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Loa Loa (eye worm) neuropeptide F receptor 0.0013 0.0062 0.0068
Onchocerca volvulus 0.0078 0.0868 0.3049
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0062 0.015
Brugia malayi cytoplasmic intermediate filament protein 0.0015 0.0079 0.0133
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0316 0.3825 1
Schistosoma mansoni rab6-interacting 0.0019 0.0138 0.0334
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.003 0.0275 0.0275
Trichomonas vaginalis CMGC family protein kinase 0.0052 0.0546 0.1426
Echinococcus granulosus low density lipoprotein receptor ldl 0.003 0.0275 0.0323
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.003 0.0275 0.0469
Onchocerca volvulus Protein ultraspiracle homolog 0.0022 0.0165 0.0514
Brugia malayi Cathepsin L-like cysteine proteinase 0.0011 0.0032 0.0054
Onchocerca volvulus 0.003 0.0275 0.0909
Onchocerca volvulus 0.0013 0.0062 0.0141
Schistosoma mansoni lipoxygenase 0.0019 0.0138 0.0334
Brugia malayi Low-density lipoprotein receptor repeat class B containing protein 0.003 0.0275 0.0469
Brugia malayi neuropeptide F receptor 0.0013 0.0062 0.0105
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0022 0.0165 0.0195
Echinococcus multilocularis tumor protein p63 0.0691 0.8501 0.8501
Echinococcus granulosus cpg binding protein 0.0031 0.0283 0.0333
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0078 0.0868 0.2102
Brugia malayi intermediate filament protein 0.0027 0.0237 0.0405
Onchocerca volvulus 0.003 0.0275 0.0909
Schistosoma mansoni neuropeptide receptor 0.0013 0.0062 0.015
Brugia malayi Inositol-1 0.0076 0.0847 0.1449
Loa Loa (eye worm) intermediate filament tail domain-containing protein 0.0027 0.0237 0.037
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0022 0.0165 0.0282
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0017
Schistosoma mansoni hypothetical protein 0.0048 0.0493 0.1195
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0022 0.0165 0.0195
Echinococcus granulosus low density lipoprotein receptor protein 0.003 0.0275 0.0323
Brugia malayi tailless protein 0.001 0.0023 0.0038
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0013 0.0062 0.0073
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Echinococcus multilocularis lamin dm0 0.0027 0.0237 0.0237
Schistosoma mansoni hypothetical protein 0.027 0.3257 0.7891
Brugia malayi hypothetical protein 0.001 0.0023 0.0038
Echinococcus granulosus cathepsin L cysteine proteinase 0.0016 0.01 0.0117
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.01 0.0259
Leishmania major hypothetical protein, conserved 0.0078 0.0868 1
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Brugia malayi hypothetical protein 0.0011 0.0038 0.0064
Mycobacterium ulcerans lipase LipD 0.0078 0.0868 0.0219
Loa Loa (eye worm) fibroinase 0.0016 0.01 0.0133
Mycobacterium tuberculosis Probable conserved lipoprotein 0.0078 0.0868 0.0225
Onchocerca volvulus Terribly reduced optic lobes homolog 0.003 0.0275 0.0909
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.003 0.0275 0.0434
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0001 0.0002
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Echinococcus granulosus fmrfamide receptor 0.0013 0.0062 0.0073
Schistosoma mansoni inositol monophosphatase 0.0076 0.0847 0.2051
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.01 0.0242
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0868 0.2267
Schistosoma mansoni hypothetical protein 0.034 0.4128 1
Echinococcus multilocularis FTZ F1 alpha 0.0022 0.0165 0.0165
Schistosoma mansoni growth hormone secretagogue receptor 0.0013 0.0062 0.015
Schistosoma mansoni lipoxygenase 0.0054 0.0574 0.1391
Echinococcus granulosus lamin 0.0027 0.0237 0.0279
Mycobacterium tuberculosis Probable fructose-bisphosphate aldolase Fba 0.0154 0.1815 0.1992
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0674 0.7766
Schistosoma mansoni subfamily S1A unassigned peptidase (S01 family) 0.003 0.0275 0.0666
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.01 0.0259
Echinococcus granulosus neuropeptide receptor A26 0.0485 0.5935 0.6982
Brugia malayi Melatonin receptor type 1A 0.0013 0.0062 0.0105
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0001
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0062 0.015
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0268 0.0268
Onchocerca volvulus 0.0097 0.1108 0.3914
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.0013 0.0062 0.0062
Schistosoma mansoni myosin xvIII 0.0013 0.0062 0.015
Echinococcus multilocularis mitogen activated protein kinase 0.0052 0.0546 0.0546
Schistosoma mansoni hypothetical protein 0.003 0.0275 0.0666
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0062 0.0062
Echinococcus multilocularis RUN 0.0019 0.0138 0.0138
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0001
Brugia malayi G protein-coupled receptor F59B2.13 0.0013 0.0062 0.0105
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0674 0.7766
Loa Loa (eye worm) hypothetical protein 0.0022 0.0165 0.0246
Mycobacterium leprae Probable lipase LipE 0.0078 0.0868 0.1132
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0062 0.0073
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Brugia malayi Cathepsin L-like precursor 0.0016 0.01 0.017
Brugia malayi CUB domain containing protein 0.003 0.0275 0.0469
Toxoplasma gondii ABC1 family protein 0.0078 0.0868 1
Schistosoma mansoni nuclear hormone receptor 0.001 0.0023 0.0055
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0194 0.2316 0.5609
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.0013 0.0062 0.0105
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Loa Loa (eye worm) nuclear hormone receptor 0.001 0.0023 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.006 0.0066
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3825 1
Echinococcus granulosus serotonin receptor 0.0013 0.0062 0.0073
Loa Loa (eye worm) hypothetical protein 0.0022 0.0165 0.0246
Schistosoma mansoni nuclear hormone receptor 0.001 0.0023 0.0055
Trichomonas vaginalis Clan CA, family C1, cathepsin L or K-like cysteine peptidase 0.0016 0.01 0.0259
Brugia malayi hypothetical protein 0.0013 0.0062 0.0105
Onchocerca volvulus 0.003 0.0275 0.0909
Schistosoma mansoni hypothetical protein 0.0013 0.0062 0.015
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0022 0.0165 0.0246
Onchocerca volvulus 0.0016 0.01 0.0278
Toxoplasma gondii inositol(myo)-1(or 4)-monophosphatase 2, putative 0.0076 0.0847 0.9724
Echinococcus multilocularis neuropeptide receptor 0.0013 0.0062 0.0062
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.0013 0.0062 0.0062
Brugia malayi Steroid receptor seven-up type 2 0.0022 0.0165 0.0282
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0022 0.0165 0.0246
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Brugia malayi Dopamine receptor protein 2 0.0013 0.0062 0.0105
Plasmodium falciparum ataxin-2 like protein, putative 0.0025 0.0202 1
Mycobacterium tuberculosis Probable esterase LipL 0.0078 0.0868 0.0225
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.003 0.0275 0.0666
Loa Loa (eye worm) hypothetical protein 0.0011 0.0038 0.0027
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.01 0.0259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0022 0.0165 0.0401
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0001
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0194 0.2316 0.2724
Brugia malayi hypothetical protein 0.011 0.1264 0.2164
Loa Loa (eye worm) hypothetical protein 0.0078 0.0868 0.1454
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0268 0.0268
Echinococcus granulosus tm gpcr rhodopsin 0.0013 0.0062 0.0073
Brugia malayi Pre-SET motif family protein 0.003 0.0268 0.0458
Mycobacterium tuberculosis Conserved protein 0.0078 0.0868 0.0225
Entamoeba histolytica cysteine proteinase, putative 0.0011 0.0032 0.0082
Schistosoma mansoni hypothetical protein 0.0048 0.0493 0.1195
Loa Loa (eye worm) hypothetical protein 0.0078 0.0868 0.1454
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0674 0.7766
Echinococcus multilocularis neuropeptide receptor 0.0013 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.0011 0.0032 0.0017
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Schistosoma mansoni low-density lipoprotein receptor (ldl) 0.003 0.0275 0.0666
Brugia malayi Serotonin receptor 0.0013 0.0062 0.0105
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0078 0.0868 0.1485
Brugia malayi Intermediate filament tail domain containing protein 0.0027 0.0237 0.0405
Brugia malayi hypothetical protein 0.0013 0.0062 0.0105
Echinococcus multilocularis g protein coupled receptor 0.0013 0.0062 0.0062
Echinococcus granulosus FTZ F1 alpha 0.0022 0.0165 0.0195
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.011 0.1264 0.1487
Brugia malayi CXXC zinc finger family protein 0.0029 0.0262 0.0448
Loa Loa (eye worm) hypothetical protein 0.0078 0.0868 0.1454
Loa Loa (eye worm) hypothetical protein 0.0013 0.0054 0.0055
Loa Loa (eye worm) doublecortin family protein 0.0019 0.0138 0.0199
Echinococcus granulosus neuropeptide receptor 0.0013 0.0062 0.0073
Schistosoma mansoni biogenic amine receptor 0.0013 0.0062 0.015
Onchocerca volvulus 0.0013 0.0062 0.0141
Schistosoma mansoni nuclear hormone receptor 0.0022 0.0165 0.0401
Echinococcus multilocularis Low density lipoprotein receptor, class A, cysteine rich 0.003 0.0275 0.0275
Brugia malayi RE15519p 0.0013 0.0062 0.0105
Echinococcus granulosus neuropeptide Y receptor 0.0013 0.0062 0.0073
Brugia malayi enteropeptidase precursor 0.003 0.0275 0.0469
Echinococcus multilocularis beta LACTamase domain containing family member 0.0078 0.0868 0.0868
Schistosoma mansoni rab6-interacting 0.0019 0.0138 0.0334
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.003 0.0275 0.0469
Echinococcus granulosus neuropeptides capa receptor 0.0013 0.0062 0.0073
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0062 0.0073
Leishmania major hypothetical protein, conserved 0.0025 0.0202 0.1327
Schistosoma mansoni hypothetical protein 0.0013 0.0062 0.015
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0022 0.0165 0.0282
Schistosoma mansoni rhodopsin-like orphan GPCR 0.0013 0.0062 0.015
Brugia malayi orphan nuclear receptor NR2E1 0.001 0.0023 0.0038
Echinococcus granulosus g protein coupled receptor 0.0013 0.0062 0.0073
Echinococcus granulosus basement membrane specific heparan sulfate 0.003 0.0275 0.0323
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0022 0.0165 0.0282
Loa Loa (eye worm) hypothetical protein 0.0101 0.1155 0.1948
Trypanosoma cruzi cruzipain precursor, putative 0.0063 0.0674 0.7766
Brugia malayi Low-density lipoprotein receptor domain class A containing protein 0.003 0.0275 0.0469
Echinococcus multilocularis neuropeptide Y receptor 0.0013 0.0062 0.0062
Trichomonas vaginalis penicillin-binding protein, putative 0.0078 0.0868 0.2267
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Echinococcus multilocularis G-protein coupled receptor, putative 0.0013 0.0062 0.0062
Echinococcus multilocularis neuropeptides capa receptor 0.0013 0.0062 0.0062
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0001
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3825 1
Echinococcus multilocularis mitogen activated protein kinase 3 0.0052 0.0546 0.0546
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0194 0.2316 0.5609
Onchocerca volvulus 0.0013 0.0062 0.0141
Loa Loa (eye worm) hypothetical protein 0.0019 0.0138 0.0199
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0063 0.0674 0.7766
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.01 0.0259
Schistosoma mansoni amine GPCR 0.0013 0.0062 0.015
Echinococcus multilocularis cathepsin L cysteine protease 0.0016 0.01 0.01
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0022 0.0165 0.0401
Loa Loa (eye worm) low-density lipoprotein receptor domain class A containing protein 0.003 0.0275 0.0434
Entamoeba histolytica fructose-1,6-bisphosphate aldolase, putative 0.0316 0.3825 1
Schistosoma mansoni hypothetical protein 0.0013 0.0062 0.015
Echinococcus granulosus geminin 0.034 0.4128 0.4856
Schistosoma mansoni transcription factor LCR-F1 0.011 0.1264 0.3061
Schistosoma mansoni neuropeptide f receptor 76f 0.0013 0.0062 0.015
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Onchocerca volvulus 0.0013 0.0062 0.0141
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Schistosoma mansoni SmCL2-like peptidase (C01 family) 0.0008 0.0001 0.0002
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0011 0.0038 0.0092
Schistosoma mansoni cathepsin F (C01 family) 0.0016 0.01 0.0242
Onchocerca volvulus Arrow homolog 0.003 0.0275 0.0909
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0022 0.0165 0.0246
Trichomonas vaginalis D-aminoacylase, putative 0.0078 0.0868 0.2267
Leishmania major cathepsin L-like protease 0.0063 0.0674 0.7478
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Brugia malayi Latrophilin receptor protein 2 0.0048 0.0493 0.0844
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0022 0.0165 0.0282
Echinococcus granulosus cathepsin l1 0.0016 0.01 0.0117
Echinococcus granulosus biogenic amine 5HT receptor 0.0013 0.0062 0.0073
Loa Loa (eye worm) hypothetical protein 0.0027 0.0231 0.0359
Echinococcus multilocularis serotonin receptor 0.0013 0.0062 0.0062
Schistosoma mansoni cellular tumor antigen P53 0.0101 0.1155 0.2798
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Mycobacterium tuberculosis Probable hydrolase 0.0078 0.0868 0.0225
Loa Loa (eye worm) hypothetical protein 0.0022 0.0165 0.0246
Brugia malayi Pre-SET motif family protein 0.0205 0.2444 0.4185
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0022 0.0165 0.0165
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0022 0.0165 0.0401
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0062 0.0062
Brugia malayi hypothetical protein 0.0025 0.0202 0.0344
Echinococcus granulosus nuclear receptor subfamily 1 group D 0.0011 0.0038 0.0045
Echinococcus granulosus lipoxygenase domain containing protein 0.0019 0.0138 0.0162
Echinococcus granulosus ecdysone induced protein 78C 0.0022 0.0165 0.0195
Plasmodium vivax hypothetical protein, conserved 0.0078 0.0868 1
Brugia malayi hypothetical protein 0.0013 0.0062 0.0105
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.0013 0.0062 0.015
Plasmodium falciparum cysteine proteinase falcipain 3 0.0016 0.01 0.4929
Echinococcus multilocularis rhodopsin orphan GPCR 0.0013 0.0062 0.0062
Echinococcus multilocularis neuropeptide FF receptor 2 0.0013 0.0062 0.0062
Echinococcus granulosus nuclear receptor 2DBD gamma 0.001 0.0023 0.0027
Brugia malayi ecdysteroid receptor 0.0022 0.0165 0.0282
Brugia malayi nuclear hormone receptor family member odr-7 0.001 0.0023 0.0038
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0194 0.2316 0.2316
Trypanosoma brucei mitogen activated protein kinase 4, putative 0.0052 0.0546 0.6288
Brugia malayi basement membrane proteoglycan precursor 0.003 0.0275 0.0469
Brugia malayi sulfakinin receptor protein 0.0013 0.0062 0.0105
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0022 0.0165 0.0401
Mycobacterium tuberculosis Conserved protein 0.0078 0.0868 0.0225
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3825 1
Brugia malayi Nuclear hormone receptor-like 1 0.0022 0.0165 0.0282
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0001
Onchocerca volvulus 0.0013 0.0062 0.0141
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.0013 0.0062 0.0073
Loa Loa (eye worm) nuclear receptor NHR-67 0.001 0.0023 0.0001
Echinococcus granulosus Nuclear hormone receptor HR96 0.001 0.0023 0.0027
Mycobacterium ulcerans fructose-bisphosphate aldolase 0.0154 0.1815 1
Loa Loa (eye worm) hypothetical protein 0.0104 0.1187 0.2002
Brugia malayi steroid hormone receptor 0.0022 0.0165 0.0282
Loa Loa (eye worm) hypothetical protein 0.0078 0.0868 0.1454
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0268 0.0649
Echinococcus multilocularis somatostatin receptor 0.0013 0.0062 0.0062
Echinococcus granulosus tumor protein p63 0.0691 0.8501 1
Echinococcus multilocularis cathepsin l cysteine peptidase 0.0016 0.01 0.01
Schistosoma mansoni biogenic amine (dopamine) receptor 0.0013 0.0062 0.015
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.0013 0.0062 0.0062
Brugia malayi hypothetical protein 0.0019 0.0138 0.0235
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.0013 0.0062 0.0062
Schistosoma mansoni RAR-like nuclear receptor 0.0022 0.0165 0.0401
Plasmodium vivax vivapain-2 0.0016 0.01 0.1143
Schistosoma mansoni peptide (allatostatin)-like receptor 0.0013 0.0062 0.015
Onchocerca volvulus 0.0027 0.0237 0.0774
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.01 0.0259
Onchocerca volvulus 0.0101 0.1155 0.4085
Echinococcus granulosus thyroid hormone receptor alpha 0.001 0.0023 0.0027
Schistosoma mansoni cpg binding protein 0.0031 0.0283 0.0686
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0001
Schistosoma mansoni neuropeptide receptor 0.0013 0.0062 0.015
Trichomonas vaginalis fructose-bisphosphate aldolase, putative 0.0316 0.3825 1
Echinococcus granulosus rhodopsin orphan GPCR 0.0013 0.0062 0.0073
Mycobacterium tuberculosis Possible conserved lipoprotein LpqK 0.0078 0.0868 0.0225
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Trypanosoma cruzi PAB1-binding protein , putative 0.0025 0.0202 0.2318
Echinococcus multilocularis Nuclear hormone receptor HR96 0.001 0.0023 0.0023
Brugia malayi nuclear hormone receptor 0.001 0.0023 0.0038
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.0013 0.0062 0.0062
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.0013 0.0062 0.015
Schistosoma mansoni biogenic amine receptor 0.0013 0.0062 0.015
Onchocerca volvulus 0.0019 0.0138 0.0415
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.0013 0.0062 0.0073
Echinococcus multilocularis cysteine protease 0.0016 0.01 0.01
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0001
Loa Loa (eye worm) hypothetical protein 0.001 0.0023 0.0001
Loa Loa (eye worm) hypothetical protein 0.003 0.0275 0.0434
Schistosoma mansoni hypothetical protein 0.0019 0.0138 0.0334
Onchocerca volvulus 0.0013 0.0062 0.0141
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Loa Loa (eye worm) follicle stimulating hormone receptor 0.0013 0.0062 0.0068
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.0013 0.0062 0.015
Schistosoma mansoni retinoic acid receptor RXR 0.0022 0.0165 0.0401
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0011 0.0032 0.0082
Brugia malayi hypothetical protein 0.0013 0.0062 0.0105
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Loa Loa (eye worm) hypothetical protein 0.0048 0.0493 0.081
Schistosoma mansoni cpg binding protein 0.0029 0.0262 0.0635
Schistosoma mansoni intermediate filament proteins 0.0027 0.0237 0.0575
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Trichomonas vaginalis Clan CA, family C1, papain-like cysteine peptidase 0.0016 0.01 0.0259
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Schistosoma mansoni cpg binding protein 0.0031 0.0283 0.0686
Echinococcus granulosus neuropeptide receptor 0.0013 0.0062 0.0073
Echinococcus multilocularis survival motor neuron protein 1 0.0477 0.5839 0.5839
Schistosoma mansoni biogenic amine (5HT) receptor 0.0013 0.0062 0.015
Loa Loa (eye worm) hypothetical protein 0.0011 0.0038 0.0027
Onchocerca volvulus Cathepsin F homolog 0.0016 0.01 0.0278
Loa Loa (eye worm) nuclear receptor nhr-7B 0.001 0.0023 0.0001
Plasmodium vivax multidomain scavenger receptor, putative 0.0019 0.0138 0.1581
Brugia malayi Nuclear hormone receptor-like 1 0.0011 0.0038 0.0064
Schistosoma mansoni hypothetical protein 0.0104 0.1187 0.2875
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0022 0.0165 0.0401
Brugia malayi Serotonin/octopamine receptor family protein 7 0.0013 0.0062 0.0105
Echinococcus multilocularis retinoic acid receptor rxr beta a retinoic acid receptor rxr alpha a retinoic acid receptor rxr alpha 0.001 0.0023 0.0023
Toxoplasma gondii CMGC kinase, MAPK family (ERK) MAPK-1 0.0052 0.0546 0.581
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Loa Loa (eye worm) hypothetical protein 0.0152 0.1785 0.303
Echinococcus granulosus histone lysine N methyltransferase MLL3 0.001 0.0022 0.0026
Echinococcus multilocularis musashi 0.0027 0.0237 0.0237
Brugia malayi beta-lactamase family protein 0.0078 0.0868 0.1485
Loa Loa (eye worm) hypothetical protein 0.0013 0.0062 0.0068
Trichomonas vaginalis Clan CA, family C1, cathepsin L-like cysteine peptidase 0.0016 0.01 0.0259
Wolbachia endosymbiont of Brugia malayi fructose-1,6-bisphosphatase 0.0076 0.0847 0.5
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.0013 0.0062 0.015
Trypanosoma brucei hypothetical protein, conserved 0.0078 0.0868 1
Loa Loa (eye worm) G-protein coupled receptor 0.0013 0.0062 0.0068
Echinococcus granulosus hypothetical protein 0.0013 0.0062 0.0073
Onchocerca volvulus 0.0016 0.01 0.0278
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.0262 0.0412
Brugia malayi beta-lactamase 0.0078 0.0868 0.1485
Echinococcus granulosus orexin receptor type 2 0.0013 0.0062 0.0073
Loa Loa (eye worm) low-density lipoprotein receptor repeat class B containing protein 0.003 0.0275 0.0434
Onchocerca volvulus 0.0013 0.0062 0.0141
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0268 0.0315
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.0013 0.0062 0.0141
Mycobacterium ulcerans hypothetical protein 0.0078 0.0868 0.0219
Mycobacterium tuberculosis Probable esterase/lipase LipP 0.0078 0.0868 0.0225
Brugia malayi larval opioid receptor 0.0013 0.0062 0.0105

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
In any case, if you have information about papers containing relevant validation data for this target, please log in using your TDR Targets username and password and send them to us using the corresponding form in this page (only visible to registered users) or contact us.

External resources for this compound

Bibliographic References

No literature references available for this target.

If you have references for this compound, please enter them in a user comment (below) or Contact us.