Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.237 | 0.237 |
Loa Loa (eye worm) | hypothetical protein | 0.011 | 0.237 | 0.237 |
Mycobacterium ulcerans | methionine aminopeptidase | 0.0045 | 0 | 0.5 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPA (MAP) (PEPTIDASE M) (MetAP) | 0.0045 | 0 | 0.5 |
Treponema pallidum | methionine aminopeptidase (map) | 0.0045 | 0 | 0.5 |
Brugia malayi | Carboxylesterase family protein | 0.0127 | 0.2986 | 0.2986 |
Loa Loa (eye worm) | hypothetical protein | 0.0163 | 0.4317 | 0.4317 |
Plasmodium vivax | methionine aminopeptidase 1a, putative | 0.0045 | 0 | 0.5 |
Loa Loa (eye worm) | carboxylesterase | 0.0127 | 0.2986 | 0.2986 |
Toxoplasma gondii | methionine aminopeptidase | 0.0045 | 0 | 0.5 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapB (map) (peptidase M) | 0.0045 | 0 | 0.5 |
Echinococcus multilocularis | carboxylesterase 5A | 0.0127 | 0.2986 | 1 |
Toxoplasma gondii | methionine aminopeptidase, type i, putative | 0.0045 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.2986 | 0.2986 |
Mycobacterium tuberculosis | Methionine aminopeptidase MapA (map) (peptidase M) (MetAP) | 0.0045 | 0 | 0.5 |
Schistosoma mansoni | biogenic amine (5HT) receptor | 0.011 | 0.237 | 0.7937 |
Plasmodium vivax | methionine aminopeptidase 1b, putative | 0.0045 | 0 | 0.5 |
Leishmania major | C-8 sterol isomerase-like protein | 0.0319 | 1 | 1 |
Echinococcus granulosus | carboxylesterase 5A | 0.0127 | 0.2986 | 1 |
Echinococcus multilocularis | serotonin receptor | 0.011 | 0.237 | 0.7937 |
Plasmodium falciparum | methionine aminopeptidase 1b, putative | 0.0045 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0319 | 1 | 1 |
Plasmodium falciparum | methionine aminopeptidase 1a, putative | 0.0045 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0127 | 0.2986 | 1 |
Chlamydia trachomatis | methionine aminopeptidase | 0.0045 | 0 | 0.5 |
Echinococcus granulosus | biogenic amine 5HT receptor | 0.011 | 0.237 | 0.7937 |
Schistosoma mansoni | family S9 non-peptidase homologue (S09 family) | 0.0127 | 0.2986 | 1 |
Mycobacterium ulcerans | methionine aminopeptidase MapB | 0.0045 | 0 | 0.5 |
Echinococcus multilocularis | serotonin receptor | 0.011 | 0.237 | 0.7937 |
Toxoplasma gondii | methionine aminopeptidase | 0.0045 | 0 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0127 | 0.2986 | 0.2986 |
Loa Loa (eye worm) | acetylcholinesterase 1 | 0.0127 | 0.2986 | 0.2986 |
Trypanosoma cruzi | C-8 sterol isomerase, putative | 0.0319 | 1 | 1 |
Brugia malayi | Carboxylesterase family protein | 0.0127 | 0.2986 | 0.2986 |
Trypanosoma brucei | C-8 sterol isomerase, putative | 0.0319 | 1 | 1 |
Echinococcus multilocularis | acetylcholinesterase | 0.0127 | 0.2986 | 1 |
Wolbachia endosymbiont of Brugia malayi | methionine aminopeptidase | 0.0045 | 0 | 0.5 |
Echinococcus granulosus | acetylcholinesterase | 0.0127 | 0.2986 | 1 |
Mycobacterium leprae | PROBABLE METHIONINE AMINOPEPTIDASE MAPB (MAP) (PEPTIDASE M) | 0.0045 | 0 | 0.5 |
Echinococcus multilocularis | acetylcholinesterase | 0.0127 | 0.2986 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.