Species | Potential target | Raw | Global | Species |
---|---|---|---|---|
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.037 | 0.9257 | 1 |
Echinococcus granulosus | diuretic hormone 44 receptor GPRdih2 | 0.0228 | 0.5147 | 0.5238 |
Brugia malayi | Putative carbonic anhydrase 5 precursor | 0.037 | 0.9257 | 0.9257 |
Brugia malayi | Latrophilin receptor protein 2 | 0.0078 | 0.0812 | 0.0812 |
Loa Loa (eye worm) | pigment dispersing factor receptor c | 0.0246 | 0.5666 | 0.5666 |
Loa Loa (eye worm) | MH2 domain-containing protein | 0.0237 | 0.5402 | 0.5402 |
Loa Loa (eye worm) | hypothetical protein | 0.0168 | 0.3419 | 0.3419 |
Brugia malayi | photoreceptor-specific nuclear receptor | 0.0241 | 0.5524 | 0.5524 |
Echinococcus granulosus | geminin | 0.0168 | 0.3417 | 0.3233 |
Brugia malayi | latrophilin 2 splice variant baaae | 0.0168 | 0.3419 | 0.3419 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.037 | 0.9257 | 1 |
Brugia malayi | hypothetical protein | 0.0071 | 0.0626 | 0.0626 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.3588 | 0.3588 |
Brugia malayi | calcium-independent alpha-latrotoxin receptor 2, putative | 0.0078 | 0.0812 | 0.0812 |
Loa Loa (eye worm) | RNA recognition domain-containing protein domain-containing protein | 0.0123 | 0.2124 | 0.2124 |
Echinococcus multilocularis | carbonic anhydrase II | 0.037 | 0.9257 | 1 |
Loa Loa (eye worm) | glutaminase 2 | 0.0267 | 0.6292 | 0.6292 |
Mycobacterium ulcerans | glutaminase | 0.0267 | 0.6292 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.2124 | 0.1736 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0174 | 0.3588 | 0.3588 |
Schistosoma mansoni | carbonic anhydrase | 0.0174 | 0.3588 | 0.3432 |
Loa Loa (eye worm) | latrophilin receptor protein 2 | 0.0078 | 0.0812 | 0.0812 |
Schistosoma mansoni | glutaminase | 0.0267 | 0.6292 | 0.6565 |
Loa Loa (eye worm) | transcription factor SMAD2 | 0.0237 | 0.5402 | 0.5402 |
Echinococcus granulosus | cadherin EGF LAG seven pass G type receptor | 0.0078 | 0.0812 | 0.0216 |
Brugia malayi | MH2 domain containing protein | 0.0237 | 0.5402 | 0.5402 |
Echinococcus multilocularis | carbonic anhydrase | 0.0174 | 0.3588 | 0.3432 |
Echinococcus granulosus | carbonic anhydrase | 0.0174 | 0.3588 | 0.3432 |
Leishmania major | carbonic anhydrase-like protein | 0.037 | 0.9257 | 1 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.3588 | 0.3588 |
Brugia malayi | glutaminase DH11.1 | 0.0267 | 0.6292 | 0.6292 |
Schistosoma mansoni | carbonic anhydrase II (carbonate dehydratase II) | 0.037 | 0.9257 | 1 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.0174 | 0.3588 | 0.3588 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0174 | 0.3588 | 0.3588 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0812 | 0.0216 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0812 | 0.0216 |
Loa Loa (eye worm) | RNA binding protein | 0.0123 | 0.2124 | 0.2124 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.3417 | 0.3233 |
Brugia malayi | RNA binding protein | 0.0123 | 0.2124 | 0.2124 |
Loa Loa (eye worm) | glutaminase | 0.0267 | 0.6292 | 0.6292 |
Trypanosoma brucei | carbonic anhydrase-like protein | 0.037 | 0.9257 | 1 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0174 | 0.3588 | 0.3588 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0626 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0241 | 0.5524 | 0.5524 |
Loa Loa (eye worm) | carbonic anhydrase 3 | 0.037 | 0.9257 | 0.9257 |
Echinococcus granulosus | carbonic anhydrase II | 0.037 | 0.9257 | 1 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.2124 | 0.1736 |
Echinococcus multilocularis | GPCR, family 2 | 0.0078 | 0.0812 | 0.0216 |
Echinococcus granulosus | tar DNA binding protein | 0.0123 | 0.2124 | 0.1736 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.3419 | 0.3236 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.2124 | 0.1736 |
Loa Loa (eye worm) | TAR-binding protein | 0.0123 | 0.2124 | 0.2124 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.0174 | 0.3588 | 0.3588 |
Echinococcus multilocularis | diuretic hormone 44 receptor GPRdih2 | 0.0228 | 0.5147 | 0.5238 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.2124 | 0.1736 |
Toxoplasma gondii | hypothetical protein | 0.0174 | 0.3588 | 1 |
Plasmodium vivax | ataxin-2 like protein, putative | 0.005 | 0 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0812 | 0.0216 |
Schistosoma mansoni | hypothetical protein | 0.0174 | 0.3588 | 0.3432 |
Brugia malayi | TAR-binding protein | 0.0123 | 0.2124 | 0.2124 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0626 | 0.5 |
Schistosoma mansoni | hypothetical protein | 0.0078 | 0.0812 | 0.0216 |
Echinococcus granulosus | carbonic anhydrase | 0.0174 | 0.3588 | 0.3432 |
Loa Loa (eye worm) | eukaryotic-type carbonic anhydrase | 0.037 | 0.9257 | 0.9257 |
Echinococcus multilocularis | carbonic anhydrase | 0.0174 | 0.3588 | 0.3432 |
Trypanosoma cruzi | carbonic anhydrase-like protein, putative | 0.037 | 0.9257 | 1 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0174 | 0.3588 | 0.3432 |
Loa Loa (eye worm) | hypothetical protein | 0.0174 | 0.3588 | 0.3588 |
Brugia malayi | Eukaryotic-type carbonic anhydrase family protein | 0.037 | 0.9257 | 0.9257 |
Echinococcus multilocularis | cadherin EGF LAG seven pass G type receptor | 0.0078 | 0.0812 | 0.0216 |
Echinococcus multilocularis | tar DNA binding protein | 0.0123 | 0.2124 | 0.1736 |
Brugia malayi | RNA recognition motif domain containing protein | 0.0123 | 0.2124 | 0.2124 |
Brugia malayi | Calcitonin receptor-like protein seb-1 | 0.0246 | 0.5666 | 0.5666 |
Loa Loa (eye worm) | hypothetical protein | 0.0078 | 0.0812 | 0.0812 |
Echinococcus multilocularis | carbonic anhydrase | 0.0174 | 0.3588 | 0.3432 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0174 | 0.3588 | 0.3432 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0626 | 0.5 |
Schistosoma mansoni | tar DNA-binding protein | 0.0123 | 0.2124 | 0.1736 |
Echinococcus granulosus | carbonic anhydrase | 0.0174 | 0.3588 | 0.3432 |
Echinococcus granulosus | GPCR family 2 | 0.0078 | 0.0812 | 0.0216 |
Plasmodium falciparum | carbonic anhydrase | 0.0174 | 0.3588 | 1 |
Brugia malayi | Carbonic anhydrase like protein 2 precursor | 0.0174 | 0.3588 | 0.3588 |
Schistosoma mansoni | hypothetical protein | 0.0168 | 0.3417 | 0.3233 |
Schistosoma mansoni | carbonic anhydrase-related | 0.0174 | 0.3588 | 0.3432 |
Trichomonas vaginalis | glutaminase, putative | 0.0267 | 0.6292 | 0.5 |
Echinococcus multilocularis | geminin | 0.0168 | 0.3417 | 0.3233 |
Entamoeba histolytica | hypothetical protein | 0.0071 | 0.0626 | 0.5 |
Loa Loa (eye worm) | hypothetical protein | 0.0396 | 1 | 1 |
Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.