Detailed information for compound 804873

Basic information

Technical information
  • TDR Targets ID: 804873
  • Name: 1-[(3-chlorophenyl)methylideneamino]-4,6-dime thyl-2-oxopyridine-3-carboxamide
  • MW: 303.744 | Formula: C15H14ClN3O2
  • H donors: 1 H acceptors: 2 LogP: 2.58 Rotable bonds: 3
    Rule of 5 violations (Lipinski): 1
  • SMILES: Clc1cccc(c1)C=Nn1c(C)cc(c(c1=O)C(=O)N)C
  • InChi: 1S/C15H14ClN3O2/c1-9-6-10(2)19(15(21)13(9)14(17)20)18-8-11-4-3-5-12(16)7-11/h3-8H,1-2H3,(H2,17,20)/b18-8+
  • InChiKey: OVDPYMCVVSUHQH-QGMBQPNBSA-N  


Substructure search Similarity search

Network

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Synonyms

  • 1-[(3-chlorophenyl)methyleneamino]-4,6-dimethyl-2-oxo-pyridine-3-carboxamide
  • 1-[(3-chlorophenyl)methyleneamino]-4,6-dimethyl-2-oxo-3-pyridinecarboxamide
  • 1-[(3-chlorobenzylidene)amino]-2-keto-4,6-dimethyl-nicotinamide
  • 1-[(3-chlorophenyl)methylideneamino]-4,6-dimethyl-2-oxo-pyridine-3-carboxamide
  • Oprea1_221181
  • A1533/0066628

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0105 0.0331
Brugia malayi Nuclear hormone receptor family member nhr-31 0.002 0.0105 0.0331
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0245 0.2216
Echinococcus granulosus potassium voltage gated channel protein 0.0264 0.3158 0.7842
Echinococcus granulosus Potassium voltage gated channel protein Shaw 0.0021 0.0124 0.0309
Echinococcus granulosus Niemann Pick C1 protein 0.0098 0.1079 0.268
Schistosoma mansoni RAR-like nuclear receptor 0.002 0.0105 0.026
Echinococcus granulosus survival motor neuron protein 1 0.0231 0.2739 0.68
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0207 0.2442 0.7732
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0331
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0331
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.0079 0.0843 0.0849
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.002 0.0105 0.026
Echinococcus multilocularis shaker cognate 0.0021 0.0124 0.0125
Brugia malayi ecdysteroid receptor 0.002 0.0105 0.0331
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0105 0.026
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0105 0.0331
Echinococcus granulosus retinoic acid receptor rxr beta a 0.002 0.0105 0.026
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0245 0.0246
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.002 0.0105 0.026
Loa Loa (eye worm) voltage-gated potassium channel 0.0021 0.0124 0.0394
Schistosoma mansoni coup transcription factor 0.002 0.0105 0.026
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0124 0.0309
Loa Loa (eye worm) MH2 domain-containing protein 0.0235 0.2795 0.8849
Loa Loa (eye worm) MH2 domain-containing protein 0.0016 0.0056 0.0177
Echinococcus multilocularis ecdysone induced protein 78C 0.002 0.0105 0.0105
Schistosoma mansoni hypothetical protein 0.004 0.0362 0.0898
Brugia malayi Nuclear hormone receptor family member nhr-1 0.002 0.0105 0.0331
Echinococcus granulosus smad 0.0016 0.0056 0.0139
Echinococcus multilocularis Basic leucine zipper (bZIP) transcription 0.0071 0.0741 0.0746
Mycobacterium ulcerans proteasome PrcA 0.0811 1 0.5
Brugia malayi Nuclear hormone receptor family member nhr-40 0.002 0.0105 0.0331
Loa Loa (eye worm) abnormal chemotaxis protein 14 0.0042 0.0381 0.1206
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0245 0.0246
Trichomonas vaginalis set domain proteins, putative 0.0235 0.2799 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0331
Loa Loa (eye worm) GTP-binding regulatory protein Gs alpha-S chain 0.0045 0.0413 0.1309
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0124 0.0309
Echinococcus granulosus voltage gated potassium channel 0.0021 0.0124 0.0309
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.003 0.0227 0.2053
Echinococcus granulosus nuclear receptor 2DBD gamma 0.002 0.0105 0.026
Schistosoma mansoni patched 1 0.0042 0.0381 0.0945
Brugia malayi photoreceptor-specific nuclear receptor 0.002 0.0105 0.0331
Echinococcus multilocularis atpase aaa+ type core atpase aaa type core 0.0806 0.9933 1
Brugia malayi isocitrate dehydrogenase 0.0031 0.0245 0.0775
Brugia malayi Probable 3',5'-cyclic phosphodiesterase R153.1, putative 0.0079 0.0843 0.2669
Trypanosoma cruzi isocitrate dehydrogenase, putative 0.0031 0.0245 1
Loa Loa (eye worm) MH1 domain-containing protein 0.0016 0.0056 0.0177
Echinococcus multilocularis protein patched 0.0042 0.0381 0.0383
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0105 0.0105
Mycobacterium tuberculosis Proteasome alpha subunit PrcA; assembles with beta subunit PrcB. 0.0811 1 1
Echinococcus granulosus Basic leucine zipper bZIP transcription 0.0071 0.0741 0.1841
Echinococcus multilocularis Smad4 0.0016 0.0056 0.0056
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0021 0.0124 0.0309
Echinococcus granulosus histone lysine methyltransferase setb 0.003 0.0227 0.0563
Brugia malayi Nuclear hormone receptor family member nhr-25 0.002 0.0105 0.0331
Brugia malayi Nuclear hormone receptor family member nhr-14 0.002 0.0105 0.0331
Loa Loa (eye worm) transcription factor SMAD2 0.0235 0.2795 0.8849
Echinococcus multilocularis isocitrate dehydrogenase 0.0031 0.0245 0.0246
Echinococcus granulosus potassium voltage gated channel subfamily A 0.0264 0.3158 0.7842
Schistosoma mansoni hypothetical protein 0.0286 0.3436 0.8531
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0413 0.0416
Schistosoma mansoni niemann-pick C1 (NPC1) 0.0099 0.1098 0.2727
Brugia malayi RNA binding protein 0.0062 0.0628 0.1989
Echinococcus multilocularis transfer RNA-Gly 0.0021 0.0124 0.0125
Echinococcus multilocularis guanine nucleotide binding protein G(s) subunit 0.0045 0.0413 0.0416
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.003 0.0227 0.0563
Echinococcus granulosus FTZ F1 alpha 0.002 0.0105 0.026
Schistosoma mansoni thyroid hormone receptor 0.002 0.0105 0.026
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.002 0.0105 0.0331
Schistosoma mansoni voltage-gated potassium channel 0.0264 0.3158 0.7842
Schistosoma mansoni camp-specific 35-cyclic phosphodiesterase 0.009 0.098 0.2433
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0413 0.1027
Schistosoma mansoni steroid hormone receptor ad4bp 0.002 0.0105 0.026
Echinococcus multilocularis isocitrate dehydrogenase 2 (NADP+) 0.0031 0.0245 0.0246
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.009 0.098 0.0987
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0331
Trypanosoma brucei isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0245 1
Brugia malayi MH2 domain containing protein 0.0016 0.0056 0.0177
Schistosoma mansoni hypothetical protein 0.0334 0.4028 1
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.002 0.0105 0.0105
Toxoplasma gondii isocitrate dehydrogenase 0.0031 0.0245 0.2216
Schistosoma mansoni TGF-beta signal transducer Smad2 0.0016 0.0056 0.0139
Onchocerca volvulus 0.002 0.0105 0.0373
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0105 0.0331
Brugia malayi Voltage-gated potassium channel, Shab-family (KCNB, Kv2-like) alpha-subunit. C. elegans exp-2 ortholog 0.0021 0.0124 0.0394
Echinococcus granulosus Protein patched homolog 1 0.0042 0.0381 0.0945
Echinococcus multilocularis Niemann Pick C1 protein 0.014 0.1604 0.1615
Onchocerca volvulus Protein ultraspiracle homolog 0.002 0.0105 0.0373
Brugia malayi nuclear hormone receptor 0.002 0.0105 0.0331
Schistosoma mansoni smad1 5 8 and 0.0016 0.0056 0.0139
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.002 0.0105 0.026
Echinococcus multilocularis potassium voltage gated channel protein 0.0021 0.0124 0.0125
Brugia malayi Nuclear hormone receptor family member nhr-49 0.002 0.0105 0.0331
Onchocerca volvulus Huntingtin homolog 0.0122 0.1378 0.4923
Echinococcus multilocularis smad 0.0016 0.0056 0.0056
Brugia malayi hypothetical protein 0.0071 0.0741 0.2348
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0124 0.0309
Schistosoma mansoni survival motor neuron protein 0.0047 0.0444 0.1102
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.002 0.0105 0.0331
Schistosoma mansoni hypothetical protein 0.0047 0.0444 0.1102
Echinococcus granulosus NADP dependent isocitrate dehydrogenase 0.0031 0.0245 0.0608
Plasmodium falciparum isocitrate dehydrogenase [NADP], mitochondrial 0.0031 0.0245 1
Onchocerca volvulus 0.0047 0.0444 0.1585
Echinococcus multilocularis protein dispatched 1 0.0048 0.0455 0.0458
Schistosoma mansoni hypothetical protein 0.0071 0.0741 0.1841
Brugia malayi Nuclear hormone receptor family member nhr-41 0.002 0.0105 0.0331
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0021 0.0124 0.0125
Echinococcus multilocularis potassium voltage gated channel subfamily A 0.0253 0.3014 0.3034
Echinococcus granulosus shaker cognate 0.0021 0.0124 0.0309
Echinococcus granulosus potassium voltage gated channel subfamily C 0.0021 0.0124 0.0309
Brugia malayi MH1 domain containing protein 0.0016 0.0056 0.0177
Brugia malayi Nuclear hormone receptor family member nhr-19 0.002 0.0105 0.0331
Echinococcus multilocularis X box binding protein 1 0.0286 0.3436 0.3459
Brugia malayi MH2 domain containing protein 0.0016 0.0056 0.0177
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.002 0.0105 0.0331
Echinococcus multilocularis mothers against decapentaplegic 5 0.0016 0.0056 0.0056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.002 0.0105 0.0331
Loa Loa (eye worm) RNA binding protein 0.0062 0.0628 0.1989
Brugia malayi Nuclear hormone receptor-like 1 0.002 0.0105 0.0331
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.002 0.0105 0.026
Brugia malayi Voltage-gated potassium channel, Shaker-family (KCNA, Kv1-like) alpha-subunit 0.0264 0.3158 1
Loa Loa (eye worm) hypothetical protein 0.0122 0.1378 0.4364
Echinococcus multilocularis sterol regulatory element binding protein 0.0042 0.0381 0.0383
Schistosoma mansoni NADP-specific isocitrate dehydrogenase 0.0031 0.0245 0.0608
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0628 0.1559
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0628 0.1559
Loa Loa (eye worm) hypothetical protein 0.009 0.098 0.3103
Loa Loa (eye worm) hypothetical protein 0.003 0.0227 0.0718
Schistosoma mansoni Tr4/Tr2 (homologue) 0.002 0.0105 0.026
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0124 0.0309
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.002 0.0105 0.026
Leishmania major isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0245 1
Loa Loa (eye worm) hypothetical protein 0.0264 0.3158 1
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0331
Loa Loa (eye worm) hypothetical protein 0.0122 0.1378 0.4364
Echinococcus multilocularis potassium voltage gated channel protein 0.0021 0.0124 0.0125
Trypanosoma brucei isocitrate dehydrogenase, putative 0.0031 0.0245 1
Brugia malayi MH2 domain containing protein 0.0235 0.2795 0.8849
Brugia malayi Smad1 0.0016 0.0056 0.0177
Loa Loa (eye worm) hypothetical protein 0.0021 0.0124 0.0394
Echinococcus multilocularis thyroid hormone receptor alpha 0.002 0.0105 0.0105
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0413 0.1027
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.0079 0.0843 0.2093
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.002 0.0105 0.0105
Brugia malayi Iron-sulfur cluster assembly accessory protein 0.0047 0.0444 0.1405
Echinococcus granulosus TGF beta signal transducer SmadC 0.0016 0.0056 0.0139
Schistosoma mansoni smad1 5 8 and 0.0016 0.0056 0.0139
Brugia malayi hypothetical protein 0.0231 0.2739 0.8672
Brugia malayi MH1 domain containing protein 0.0016 0.0056 0.0177
Brugia malayi RNA recognition motif domain containing protein 0.0062 0.0628 0.1989
Plasmodium vivax isocitrate dehydrogenase [NADP], mitochondrial, putative 0.0031 0.0245 1
Echinococcus granulosus Niemann Pick C1 protein 0.014 0.1604 0.3983
Echinococcus multilocularis FTZ F1 alpha 0.002 0.0105 0.0105
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0227 0.0563
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.002 0.0105 0.0331
Brugia malayi TAR-binding protein 0.0062 0.0628 0.1989
Echinococcus multilocularis survival motor neuron protein 1 0.0231 0.2739 0.2757
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.009 0.098 0.2433
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.003 0.0227 0.0228
Echinococcus multilocularis geminin 0.0334 0.4028 0.4055
Echinococcus multilocularis Niemann Pick C1 protein 0.0098 0.1079 0.1087
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0413 0.1027
Loa Loa (eye worm) Smad1 0.0016 0.0056 0.0177
Schistosoma mansoni smad 0.0016 0.0056 0.0139
Schistosoma mansoni Smad4 0.0016 0.0056 0.0139
Echinococcus multilocularis potassium voltage gated channel subfamily C 0.0021 0.0124 0.0125
Echinococcus granulosus guanine nucleotide binding protein Gs subunit 0.0045 0.0413 0.1027
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.002 0.0105 0.0331
Schistosoma mansoni hypothetical protein 0.0334 0.4028 1
Echinococcus multilocularis potassium voltage gated channel subfamily D 0.0021 0.0124 0.0125
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0331
Echinococcus multilocularis TGF beta signal transducer SmadC 0.0016 0.0056 0.0056
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.002 0.0105 0.0331
Schistosoma mansoni nuclear hormone receptor 0.002 0.0105 0.026
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.002 0.0105 0.0105
Brugia malayi Pre-SET motif family protein 0.003 0.0227 0.0718
Schistosoma mansoni smad1 5 8 and 0.0016 0.0056 0.0139
Brugia malayi Niemann-Pick C1 protein precursor 0.0098 0.1079 0.3417
Echinococcus granulosus expressed conserved protein 0.0092 0.1005 0.2495
Echinococcus granulosus sterol regulatory element binding protein 0.0042 0.0381 0.0945
Brugia malayi steroid hormone receptor 0.002 0.0105 0.0331
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0331
Brugia malayi nuclear receptor NHR-88 0.002 0.0105 0.0331
Schistosoma mansoni vesicular amine transporter 0.0021 0.0124 0.0309
Brugia malayi CHE-14 protein 0.0042 0.0381 0.1206
Echinococcus multilocularis NADP dependent isocitrate dehydrogenase 0.0031 0.0245 0.0246
Entamoeba histolytica Niemann-Pick C1 protein, putative 0.0098 0.1079 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0227 0.0563
Loa Loa (eye worm) isocitrate dehydrogenase 0.0031 0.0245 0.0775
Schistosoma mansoni hypothetical protein 0.004 0.0362 0.0898
Schistosoma mansoni retinoid-x-receptor (RXR) 0.002 0.0105 0.026
Loa Loa (eye worm) hypothetical protein 0.0231 0.2739 0.8672
Loa Loa (eye worm) cyclic AMP specific phosphodiesterase PDE4D5A 0.0079 0.0843 0.2669
Onchocerca volvulus Bile acid receptor homolog 0.002 0.0105 0.0373
Schistosoma mansoni hypothetical protein 0.004 0.0362 0.0898
Echinococcus multilocularis tar DNA binding protein 0.0062 0.0628 0.0632
Brugia malayi GTP-binding regulatory protein Gs alpha-S chain, putative 0.0045 0.0413 0.1309
Loa Loa (eye worm) hypothetical protein 0.002 0.0105 0.0331
Loa Loa (eye worm) hypothetical protein 0.0098 0.1079 0.3417
Echinococcus granulosus cAMP specific 3'5' cyclic phosphodiesterase 0.009 0.098 0.2433
Onchocerca volvulus 0.003 0.0227 0.081
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0213 0.0529
Loa Loa (eye worm) hypothetical protein 0.0042 0.0381 0.1206
Brugia malayi Pre-SET motif family protein 0.0207 0.2442 0.7732
Trypanosoma cruzi isocitrate dehydrogenase [NADP], mitochondrial precursor, putative 0.0031 0.0245 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.003 0.0227 0.0563
Echinococcus granulosus potassium voltage gated channel protein 0.0021 0.0124 0.0309
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0628 0.1559
Schistosoma mansoni Guanine nucleotide-binding protein G(s) subunit alpha (Adenylate cyclase-stimulating G alpha protein) 0.0045 0.0413 0.1027
Schistosoma mansoni voltage-gated potassium channel 0.0264 0.3158 0.7842
Echinococcus granulosus mothers against decapentaplegic 5 0.0016 0.0056 0.0139
Brugia malayi Isocitrate dehydrogenase 0.0031 0.0245 0.0775
Giardia lamblia CAMP-specific 3,5-cyclic phosphodiesterase 4B 0.009 0.098 0.5
Echinococcus granulosus potassium voltage gated channel protein 0.0021 0.0124 0.0309
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0124 0.0309
Loa Loa (eye worm) steroid hormone receptor 0.002 0.0105 0.0331
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.002 0.0105 0.0331
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.01 0.1104 1
Loa Loa (eye worm) TAR-binding protein 0.0062 0.0628 0.1989
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.002 0.0105 0.026
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0628 0.1559
Onchocerca volvulus Steroid hormone receptor family member cnr14 homolog 0.002 0.0105 0.0373
Onchocerca volvulus Huntingtin homolog 0.0122 0.1378 0.4923
Onchocerca volvulus 0.0235 0.2799 1
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.003 0.0227 0.0228
Echinococcus granulosus geminin 0.0334 0.4028 1
Loa Loa (eye worm) RNA recognition domain-containing protein domain-containing protein 0.0062 0.0628 0.1989
Loa Loa (eye worm) hypothetical protein 0.0051 0.0499 0.158
Schistosoma mansoni voltage-gated potassium channel 0.0021 0.0124 0.0309
Schistosoma mansoni thyroid hormone receptor 0.002 0.0105 0.026
Echinococcus granulosus X box binding protein 1 0.0286 0.3436 0.8531
Brugia malayi Steroid receptor seven-up type 2 0.002 0.0105 0.0331
Brugia malayi Voltage-gated potassium channel, Shaw-family (KCNC, Kv3-like) alpha-subunit 0.0021 0.0124 0.0394
Schistosoma mansoni retinoic acid receptor RXR 0.002 0.0105 0.026
Echinococcus granulosus ecdysone induced protein 78C 0.002 0.0105 0.026
Toxoplasma gondii 3'5'-cyclic nucleotide phosphodiesterase domain-containing protein 0.0021 0.0117 0.106
Echinococcus multilocularis cAMP specific 3',5' cyclic phosphodiesterase 0.009 0.098 0.0987
Brugia malayi Nuclear hormone receptor family member nhr-3 0.002 0.0105 0.0331
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.002 0.0105 0.0105
Schistosoma mansoni tar DNA-binding protein 0.0062 0.0628 0.1559
Echinococcus multilocularis expressed conserved protein 0.0092 0.1005 0.1012
Echinococcus granulosus Smad4 0.0016 0.0056 0.0139
Plasmodium vivax SET domain protein, putative 0.003 0.0227 0.9265
Schistosoma mansoni hypothetical protein 0.004 0.0362 0.0898
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.002 0.0105 0.0105
Brugia malayi hypothetical protein 0.0122 0.1378 0.4364
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.002 0.0105 0.026
Echinococcus granulosus potassium voltage gated channel subfamily D 0.0021 0.0124 0.0309
Echinococcus multilocularis potassium voltage gated channel protein 0.0264 0.3158 0.318
Echinococcus multilocularis voltage gated potassium channel 0.0021 0.0124 0.0125
Echinococcus granulosus tar DNA binding protein 0.0062 0.0628 0.1559
Schistosoma mansoni transcription factor LCR-F1 0.0071 0.0741 0.1841
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.002 0.0105 0.026

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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