Detailed information for compound 805154

Basic information

Technical information
  • Name: Unnamed compound
  • MW: 443.923 | Formula: C23H26ClN3O4
  • H donors: 1 H acceptors: 2 LogP: 4.19 Rotable bonds: 7
    Rule of 5 violations (Lipinski): 1
  • SMILES: CCOC(=O)N1CCC(CC1)N1C(Nc2cc(Cl)ccc2OC)c2c(C1=O)cccc2
  • InChi: 1S/C23H26ClN3O4/c1-3-31-23(29)26-12-10-16(11-13-26)27-21(17-6-4-5-7-18(17)22(27)28)25-19-14-15(24)8-9-20(19)30-2/h4-9,14,16,21,25H,3,10-13H2,1-2H3
  • InChiKey: PGWKSYRGLMXBQG-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

No synonyms found for this compound

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Echinococcus granulosus leukotriene A 4 hydrolase 0.0146 0.0304 0.0302
Onchocerca volvulus 0.015 0.0313 0.1555
Loa Loa (eye worm) hypothetical protein 0.0519 0.1207 0.4869
Brugia malayi cell division control protein 2 homolog 0.0091 0.0171 0.0414
Toxoplasma gondii calcium-dependent protein kinase CDPK3 0.0068 0.0116 0.0784
Brugia malayi Hsp90 protein 0.0026 0.0015 0.0032
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0017 0.0016
Onchocerca volvulus 0.082 0.1936 1
Leishmania major cathepsin L-like protease 0.0064 0.0104 0.1082
Mycobacterium tuberculosis Possible penicillin-binding protein 0.0229 0.0506 0.0831
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 1 0.0068 0.0116 0.0115
Schistosoma mansoni RAR-like nuclear receptor 0.0026 0.0014 0.0013
Schistosoma mansoni Tr4/Tr2 (homologue) 0.0026 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.082 0.1936 1
Entamoeba histolytica protein kinase, putative 0.0068 0.0116 0.1082
Brugia malayi Cyclin, N-terminal domain containing protein 0.0127 0.0259 0.0629
Trypanosoma brucei beta tubulin 0.0229 0.0504 0.2863
Brugia malayi Nuclear hormone receptor family member nhr-31 0.0026 0.0014 0.0031
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.0171 0.1063
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Echinococcus granulosus g protein coupled receptor 0.082 0.1936 0.1935
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.0177 0.0378 0.0377
Echinococcus granulosus neuropeptide receptor 0.082 0.1936 0.1935
Echinococcus granulosus insulin growth factor 1 receptor beta 0.0051 0.0073 0.0072
Brugia malayi beta-lactamase 0.0036 0.0037 0.0088
Echinococcus multilocularis g protein coupled receptor 0.082 0.1936 0.1935
Echinococcus granulosus melanoma receptor tyrosine protein kinase 0.0079 0.0141 0.014
Echinococcus granulosus FTZ F1 alpha 0.0026 0.0014 0.0013
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.015 0.0313 0.0312
Loa Loa (eye worm) leukotriene A4 hydrolase 0.0146 0.0304 0.1221
Onchocerca volvulus Glucosylceramidase homolog 0.0177 0.038 0.1902
Echinococcus granulosus Tubulin beta 2C chain 0.0229 0.0504 0.0503
Echinococcus granulosus leucine aminopeptidase protein 0.0105 0.0205 0.0204
Loa Loa (eye worm) pre-SET domain-containing protein family protein 0.0211 0.0461 0.1856
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Loa Loa (eye worm) nuclear hormone receptor family member nhr-40 0.0026 0.0014 0.0052
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0104 0.0587
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.0146
Loa Loa (eye worm) beta-LACTamase domain containing family member 0.0036 0.0037 0.0146
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.082 0.1936 0.1935
Schistosoma mansoni biogenic amine (dopamine) receptor 0.082 0.1936 0.1935
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0415 0.0955 0.0954
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0116 0.0115
Brugia malayi Angiotensin-converting enzyme family protein 0.0629 0.1473 0.3593
Entamoeba histolytica aminopeptidase, putative 0.0415 0.0955 1
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0037 0.004 0.0176
Echinococcus granulosus neuropeptide Y receptor 0.082 0.1936 0.1935
Echinococcus multilocularis cyclins 0.0064 0.0105 0.0104
Echinococcus multilocularis rhodopsin orphan GPCR 0.082 0.1936 0.1935
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0032 0.0116
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Brugia malayi neuropeptide F receptor 0.082 0.1936 0.4724
Onchocerca volvulus 0.0029 0.002 0.0029
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0091 0.0171 0.0684
Loa Loa (eye worm) glutamate receptor 2 0.0032 0.0028 0.0109
Echinococcus multilocularis endoplasmin 0.0088 0.0164 0.0163
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0014 0.0013
Leishmania major aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0415 0.0955 1
Echinococcus granulosus peptide allatostatin:somatostatin 0.082 0.1936 0.1935
Brugia malayi hypothetical protein 0.082 0.1936 0.4724
Schistosoma mansoni thyroid hormone receptor 0.028 0.0628 0.0627
Schistosoma mansoni peptide (allatostatin)-like receptor 0.082 0.1936 0.1935
Echinococcus multilocularis glutamate (NMDA) receptor subunit 0.0271 0.0606 0.0605
Leishmania major cell division related protein kinase 2,cdc2-related kinase 0.0091 0.0171 0.1777
Leishmania major heat shock protein, putative 0.0026 0.0015 0.014
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0052
Toxoplasma gondii aminopeptidase N protein 0.0146 0.0304 0.2047
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0037 0.0036
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.007 0.0119 0.0118
Brugia malayi Serotonin receptor 0.082 0.1936 0.4724
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.0088 0.0164 0.0225
Schistosoma mansoni serine-type protease inhibitor 0.4028 0.9701 0.9701
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Schistosoma mansoni tyrosine kinase 0.0146 0.0305 0.0304
Echinococcus granulosus ecdysone induced protein 78C 0.0026 0.0014 0.0013
Brugia malayi ecdysteroid receptor 0.0026 0.0014 0.0031
Echinococcus granulosus Tubulin beta 2C chain 0.0229 0.0504 0.0503
Echinococcus multilocularis Furin 1 0.0034 0.0032 0.003
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.015 0.0313 0.0312
Trypanosoma brucei cdc2-related kinase 1 0.0091 0.0171 0.0964
Loa Loa (eye worm) tubulin beta chain 0.0229 0.0504 0.2032
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0049 0.0068 0.0067
Onchocerca volvulus 0.082 0.1936 1
Echinococcus granulosus rhodopsin orphan GPCR 0.082 0.1936 0.1935
Brugia malayi hypothetical protein 0.082 0.1936 0.4724
Trypanosoma cruzi cdc2-related kinase 1 0.0091 0.0171 0.1777
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Trypanosoma brucei cdc2-related kinase 3 0.0091 0.0171 0.0964
Schistosoma mansoni hypothetical protein 0.0177 0.0378 0.0377
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Echinococcus granulosus rhodopsin orphan GPCR 0.082 0.1936 0.1935
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.015 0.0313 0.0312
Echinococcus multilocularis Ribosomal protein S1, RNA binding domain 0.0032 0.0028 0.0027
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Schistosoma mansoni matrix metallopeptidase-9 (M10 family) 0.0035 0.0035 0.0034
Loa Loa (eye worm) TATA binding protein associated factor 0.0146 0.0304 0.1221
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0037 0.0155
Trichomonas vaginalis cyclin D, putative 0.0064 0.0105 0.0618
Trypanosoma brucei beta tubulin 0.0229 0.0504 0.2863
Echinococcus multilocularis neuropeptide FF receptor 2 0.082 0.1936 0.1935
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Brugia malayi Cam kinase protein 1 0.0068 0.0116 0.0281
Echinococcus granulosus Alpha N acetylgalactosaminidase 0.0104 0.0203 0.0202
Loa Loa (eye worm) nuclear hormone receptor family member nhr-1 0.0026 0.0014 0.0052
Echinococcus granulosus Ribosomal protein S1 RNA binding domain 0.0032 0.0028 0.0027
Onchocerca volvulus 0.015 0.0313 0.1555
Trypanosoma cruzi cyclin 6, putative 0.0127 0.0259 0.2701
Schistosoma mansoni opsin-like receptor 0.082 0.1936 0.1935
Brugia malayi Protein kinase domain containing protein 0.0038 0.0042 0.01
Echinococcus multilocularis cpg binding protein 0.003 0.0023 0.0022
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0037 0.0155
Echinococcus granulosus neuroendocrine convertase 2 0.0089 0.0166 0.0165
Plasmodium vivax tubulin beta chain, putative 0.0229 0.0504 0.3335
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.015 0.0313 0.0312
Schistosoma mansoni photoreceptor-specific nuclear receptor related 0.0026 0.0014 0.0013
Toxoplasma gondii leucyl aminopeptidase LAP 0.0105 0.0205 0.1383
Schistosoma mansoni glutamate receptor NMDA 0.0271 0.0606 0.0605
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Brugia malayi Furin-like cysteine rich region family protein 0.0146 0.0305 0.0741
Plasmodium falciparum plasmepsin II 0.0633 0.1484 1
Schistosoma mansoni cpg binding protein 0.003 0.0023 0.0022
Echinococcus granulosus neuropeptides capa receptor 0.082 0.1936 0.1935
Echinococcus multilocularis beta tubulin 0.0229 0.0504 0.0503
Loa Loa (eye worm) nuclear hormone receptor family member nhr-14 0.0026 0.0014 0.0052
Schistosoma mansoni nuclear receptor 2DBD-gamma 0.0026 0.0014 0.0013
Schistosoma mansoni glutamate receptor AMPA 0.0032 0.0028 0.0027
Echinococcus granulosus nmda type glutamate receptor 0.0114 0.0227 0.0226
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0104 0.0587
Schistosoma mansoni glutamate receptor NMDA 0.0049 0.0068 0.0067
Brugia malayi nuclear hormone receptor 0.0026 0.0014 0.0031
Brugia malayi Kringle domain containing protein 0.0037 0.004 0.0095
Echinococcus multilocularis sex peptide receptor 0.082 0.1936 0.1935
Echinococcus multilocularis insulin receptor 0.0047 0.0064 0.0063
Plasmodium vivax heat shock protein 86, putative 0.0101 0.0196 0.1234
Schistosoma mansoni protein kinase 0.055 0.1283 0.1282
Echinococcus multilocularis g-protein coupled receptor 0.082 0.1936 0.1935
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0116 0.0115
Echinococcus granulosus calcium dependent protein kinase 0.0065 0.0109 0.0108
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.082 0.1936 0.1935
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.0203 0.0202
Echinococcus granulosus tubulin beta 1 chain 0.0229 0.0504 0.0503
Echinococcus multilocularis aminopeptidase N 0.0665 0.156 0.1559
Echinococcus multilocularis hepatocyte nuclear factor 4 alpha 0.0026 0.0014 0.0013
Trichomonas vaginalis cyclins, putative 0.0079 0.0141 0.0863
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0104 0.0587
Echinococcus multilocularis cyclins 0.0064 0.0105 0.0104
Trichomonas vaginalis conserved hypothetical protein 0.0064 0.0105 0.0618
Loa Loa (eye worm) glutaminase 0.0273 0.061 0.2459
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0052
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.082 0.1936 0.7814
Trypanosoma brucei heat shock protein, putative 0.0101 0.0196 0.1107
Echinococcus granulosus cyclin dependent kinase 1 0.0091 0.0171 0.0169
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.082 0.1936 0.1935
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.0146
Loa Loa (eye worm) TK/EGFR protein kinase 0.0146 0.0305 0.1226
Loa Loa (eye worm) TK/ROR protein kinase 0.0041 0.005 0.0198
Loa Loa (eye worm) tubulin beta-4 chain 0.0229 0.0504 0.2032
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.082 0.1936 0.7814
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.082 0.1936 0.4724
Echinococcus granulosus furin 0.0142 0.0294 0.0293
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.027 0.0604 0.2436
Schistosoma mansoni neuropeptide F-like receptor 0.082 0.1936 0.1935
Echinococcus granulosus myosin light chain kinase smooth muscle 0.0268 0.06 0.0599
Schistosoma mansoni endoplasmin 0.0101 0.0196 0.0195
Trichomonas vaginalis cyclin B, putative 0.0127 0.0259 0.1663
Entamoeba histolytica cell division protein kinase 2, putative 0.0091 0.0171 0.166
Loa Loa (eye worm) hypothetical protein 0.0146 0.0304 0.1221
Echinococcus multilocularis Glycoside hydrolase, family 27 0.0104 0.0203 0.0202
Schistosoma mansoni coup transcription factor 0.0026 0.0014 0.0013
Plasmodium vivax plasmepsin IV, putative 0.0633 0.1484 1
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.0716 0.1685 0.411
Echinococcus granulosus endoplasmin 0.0088 0.0164 0.0163
Trypanosoma cruzi metallo-peptidase, Clan MF, Family M17, putative 0.0105 0.0205 0.2138
Plasmodium vivax aspartyl protease, putative 0.015 0.0313 0.2031
Schistosoma mansoni cyclin B3 0.0064 0.0105 0.0104
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Brugia malayi Dopamine receptor 0.082 0.1936 0.4724
Schistosoma mansoni serine-type protease inhibitor 0.4028 0.9701 0.9701
Leishmania major CYC2-like cyclin, putative,cyclin 6, putative 0.0127 0.0259 0.2701
Trypanosoma cruzi aminopeptidase, putative 0.0415 0.0955 1
Onchocerca volvulus Heat shock protein 75 kDa, mitochondrial homolog 0.0026 0.0015 0.0003
Echinococcus multilocularis rhodopsin orphan GPCR 0.082 0.1936 0.1935
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0049 0.0068 0.0067
Giardia lamblia Beta tubulin 0.0229 0.0504 1
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Schistosoma mansoni cytosol alanyl aminopeptidase (M01 family) 0.0415 0.0955 0.0954
Brugia malayi CXXC zinc finger family protein 0.0029 0.002 0.0045
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0146 0.0304 0.1968
Mycobacterium tuberculosis 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) 0.2363 0.5671 1
Trypanosoma brucei heat shock protein, putative 0.0101 0.0196 0.1107
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.0177 0.0378 0.0377
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0415 0.0955 0.6403
Brugia malayi Steroid receptor seven-up type 2 0.0026 0.0014 0.0031
Plasmodium falciparum plasmepsin VI 0.0633 0.1484 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0049 0.0068 0.0067
Brugia malayi hypothetical protein 0.082 0.1936 0.4724
Echinococcus multilocularis insulin growth factor 1 receptor beta 0.0051 0.0073 0.0072
Schistosoma mansoni FTZ-F1 nuclear receptor-like protein 0.0026 0.0014 0.0013
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.082 0.1936 0.1935
Brugia malayi G protein-coupled receptor 0.082 0.1936 0.4724
Echinococcus multilocularis g protein coupled receptor 0.082 0.1936 0.1935
Trichomonas vaginalis cyclin D, putative 0.0064 0.0105 0.0618
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.0146
Trypanosoma brucei hypothetical protein, conserved 0.0036 0.0037 0.0206
Loa Loa (eye worm) nuclear hormone receptor family member nhr-41 0.0026 0.0014 0.0052
Trypanosoma cruzi aminopeptidase, putative 0.0146 0.0304 0.3171
Schistosoma mansoni ATP-binding cassette transporter 0.0032 0.0028 0.0027
Schistosoma mansoni hypothetical protein 0.0027 0.0017 0.0016
Schistosoma mansoni steroid hormone receptor ad4bp 0.0026 0.0014 0.0013
Echinococcus granulosus cpg binding protein 0.003 0.0023 0.0022
Trichomonas vaginalis tubulin beta chain, putative 0.0229 0.0504 0.3335
Schistosoma mansoni retinoic acid receptor RXR 0.0026 0.0014 0.0013
Echinococcus granulosus tissue type plasminogen activator 0.0037 0.004 0.0039
Loa Loa (eye worm) nuclear hormone receptor family member nhr-49 0.0026 0.0014 0.0052
Leishmania major hypothetical protein, conserved 0.0036 0.0037 0.0379
Echinococcus multilocularis glutamate receptor subunit protein glur 0.0032 0.0028 0.0027
Echinococcus granulosus thyrotropin releasing hormone receptor 0.082 0.1936 0.1935
Schistosoma mansoni biogenic amine (dopamine) receptor 0.082 0.1936 0.1935
Echinococcus multilocularis neuropeptide Y receptor 0.082 0.1936 0.1935
Toxoplasma gondii calcium-dependent protein kinase CDPK2B 0.0068 0.0116 0.0784
Echinococcus granulosus insulin receptor 0.0047 0.0064 0.0063
Trypanosoma cruzi Aminopeptidase M1, putative 0.0415 0.0955 1
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0025 0.0024
Echinococcus granulosus beta tubulin 0.0229 0.0504 0.0503
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.082 0.1936 0.1935
Plasmodium vivax plasmepsin V, putative 0.015 0.0313 0.2031
Loa Loa (eye worm) TYRA-2 protein 0.082 0.1936 0.7814
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0014 0.0031
Loa Loa (eye worm) hypothetical protein 0.0063 0.0104 0.0415
Echinococcus multilocularis histone lysine N methyltransferase SETMAR 0.0031 0.0025 0.0024
Echinococcus multilocularis neuropeptide s receptor 0.082 0.1936 0.1935
Schistosoma mansoni rhodopsin-like orphan GPCR 0.082 0.1936 0.1935
Trypanosoma cruzi major cysteine proteinase, putative 0.005 0.0071 0.0736
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0037 0.0155
Trichomonas vaginalis cyclins, putative 0.0064 0.0105 0.0618
Loa Loa (eye worm) hypothetical protein 0.0127 0.0259 0.104
Loa Loa (eye worm) latrophilin receptor protein 2 0.0177 0.0378 0.1523
Loa Loa (eye worm) hypothetical protein 0.025 0.0556 0.2239
Echinococcus multilocularis histone lysine methyltransferase setb histone lysine methyltransferase eggless 0.0031 0.0025 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.038 0.2485
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0171 0.0169
Trypanosoma brucei Aminopeptidase M1, putative 0.0415 0.0955 0.5427
Leishmania major cytosolic leucyl aminopeptidase,metallo-peptidase, Clan MF, Family M17 0.0105 0.0205 0.2138
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0068 0.0116 0.0281
Echinococcus multilocularis Alpha N acetylgalactosaminidase 0.0104 0.0203 0.0202
Trichomonas vaginalis cyclin A, putative 0.0127 0.0259 0.1663
Brugia malayi aspartic protease BmAsp-2, identical 0.015 0.0313 0.0761
Echinococcus granulosus 7tm_1 domain containing protein 0.082 0.1936 0.1935
Entamoeba histolytica tubulin family protein 0.0229 0.0504 0.5209
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0052
Echinococcus granulosus g protein coupled receptor 0.082 0.1936 0.1935
Schistosoma mansoni retinoid-x-receptor (RXR) 0.0026 0.0014 0.0013
Brugia malayi steroid hormone receptor 0.0026 0.0014 0.0031
Loa Loa (eye worm) hypothetical protein 0.0382 0.0875 0.3527
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0104 0.1082
Echinococcus multilocularis glutamate receptor 2 0.0049 0.0068 0.0067
Schistosoma mansoni glutaminase 0.0273 0.061 0.0609
Echinococcus multilocularis rhodopsin orphan GPCR 0.082 0.1936 0.1935
Onchocerca volvulus 0.024 0.0531 0.2691
Echinococcus granulosus rhodopsin orphan GPCR 0.082 0.1936 0.1935
Trypanosoma cruzi cytosolic leucyl aminopeptidase, putative 0.0105 0.0205 0.2138
Echinococcus granulosus fmrfamide receptor 0.082 0.1936 0.1935
Plasmodium falciparum calcium-dependent protein kinase 4 0.0068 0.0116 0.0693
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Loa Loa (eye worm) hypothetical protein 0.0716 0.1685 0.6798
Echinococcus multilocularis G-protein coupled receptor, putative 0.082 0.1936 0.1935
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.0146
Onchocerca volvulus 0.082 0.1936 1
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Echinococcus granulosus tachykinin peptides receptor 99D 0.082 0.1936 0.1935
Echinococcus multilocularis dnaJ subfamily B 0.0406 0.0934 0.0933
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Plasmodium falciparum calcium-dependent protein kinase 1 0.0068 0.0116 0.0693
Schistosoma mansoni protein kinase 0.055 0.1283 0.1282
Onchocerca volvulus 0.082 0.1936 1
Trypanosoma cruzi heat shock protein 85, putative 0.0101 0.0196 0.2041
Entamoeba histolytica cyclin, putative 0.0064 0.0105 0.0966
Echinococcus multilocularis rhodopsin orphan GPCR 0.082 0.1936 0.1935
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0116 0.0115
Loa Loa (eye worm) BEN-1 protein 0.0229 0.0504 0.2032
Plasmodium falciparum plasmepsin X 0.015 0.0313 0.2031
Echinococcus granulosus G2:mitotic specific cyclin B3 0.0064 0.0105 0.0104
Brugia malayi hypothetical protein 0.082 0.1936 0.4724
Brugia malayi Pre-SET motif family protein 0.0211 0.0461 0.1122
Schistosoma mansoni heat shock protein 0.0101 0.0196 0.0195
Echinococcus multilocularis ecdysone induced protein 78C 0.0026 0.0014 0.0013
Echinococcus multilocularis epidermal growth factor receptor 0.0079 0.0141 0.014
Plasmodium falciparum calcium-dependent protein kinase 2 0.0068 0.0116 0.0693
Toxoplasma gondii heat shock protein HSP90 0.0101 0.0196 0.132
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.0068 0.0116 0.0115
Echinococcus granulosus heat shock protein 75 kDa mitochondrial 0.0026 0.0015 0.0013
Echinococcus granulosus heat shock protein 90 0.0088 0.0164 0.0163
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0104 0.0587
Entamoeba histolytica protein kinase, putative 0.0068 0.0116 0.1082
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.082 0.1936 0.4724
Schistosoma mansoni memapsin-2 (A01 family) 0.015 0.0313 0.0312
Echinococcus granulosus cyclin dependent kinase 5 0.0091 0.0171 0.0169
Toxoplasma gondii beta-tubulin, putative 0.0229 0.0504 0.34
Trypanosoma brucei Heat shock protein 83, putative 0.0101 0.0196 0.1107
Schistosoma mansoni adenoreceptor 0.082 0.1936 0.1935
Echinococcus granulosus 5'partial|histone lysine N methyltransferase SETDB2 0.0029 0.0021 0.002
Toxoplasma gondii aspartyl protease 0.015 0.0313 0.2109
Plasmodium falciparum cyclin 0.0064 0.0105 0.0618
Echinococcus multilocularis G protein coupled receptor 139 0.4151 1 1
Loa Loa (eye worm) peptidase family M1 containing protein 0.0396 0.0909 0.3665
Loa Loa (eye worm) steroid hormone receptor 0.0026 0.0014 0.0052
Schistosoma mansoni aminopeptidase A (M01 family) 0.0146 0.0304 0.0302
Brugia malayi beta-tubulin, identical 0.0229 0.0504 0.1229
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0014 0.0031
Echinococcus multilocularis glutamate receptor 2 0.0032 0.0028 0.0027
Schistosoma mansoni tyrosine kinase 0.0047 0.0064 0.0063
Echinococcus granulosus glutamate receptor ionotropic kainate 0.0032 0.0028 0.0027
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.082 0.1936 0.1935
Schistosoma mansoni biogenic amine (5HT) receptor 0.082 0.1936 0.1935
Plasmodium falciparum plasmepsin IV 0.0633 0.1484 1
Echinococcus multilocularis cyclins 0.0064 0.0105 0.0104
Schistosoma mansoni subfamily S8B unassigned peptidase (S08 family) 0.0142 0.0294 0.0293
Schistosoma mansoni hypothetical protein 0.0037 0.004 0.0039
Echinococcus multilocularis Tubulin beta 2C chain 0.0229 0.0504 0.0503
Echinococcus granulosus cyclins 0.0064 0.0105 0.0104
Plasmodium falciparum heat shock protein 90 0.0101 0.0196 0.1234
Echinococcus granulosus biogenic amine 5HT receptor 0.082 0.1936 0.1935
Schistosoma mansoni tubulin subunit beta 0.0229 0.0504 0.0503
Giardia lamblia Beta tubulin 0.0229 0.0504 1
Echinococcus multilocularis NMDA receptor 0.0032 0.0028 0.0027
Entamoeba histolytica cell division protein kinase 2, putative 0.0091 0.0171 0.166
Onchocerca volvulus 0.0037 0.004 0.0137
Schistosoma mansoni rhodopsin-like orphan GPCR 0.082 0.1936 0.1935
Trypanosoma brucei beta tubulin 0.0229 0.0504 0.2863
Schistosoma mansoni rhodopsin-like orphan GPCR 0.082 0.1936 0.1935
Loa Loa (eye worm) neuropeptide F receptor 0.082 0.1936 0.7814
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase subunit type II alpha 0.0482 0.1117 0.4505
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.082 0.1936 0.1935
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.015 0.0313 0.0312
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.082 0.1936 0.1935
Echinococcus granulosus Tubulin beta 2C chain 0.0229 0.0504 0.0503
Plasmodium falciparum calcium-dependent protein kinase 3 0.0068 0.0116 0.0693
Loa Loa (eye worm) hypothetical protein 0.015 0.0313 0.1259
Schistosoma mansoni histone-lysine n-methyltransferase suv9 0.0031 0.0025 0.0024
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.082 0.1936 0.1935
Schistosoma mansoni family S12 unassigned peptidase (S12 family) 0.0036 0.0037 0.0036
Echinococcus multilocularis epidermal growth factor receptor 0.0146 0.0305 0.0304
Trichomonas vaginalis penicillin-binding protein, putative 0.0036 0.0037 0.0155
Brugia malayi Nuclear hormone receptor family member nhr-40 0.0026 0.0014 0.0031
Giardia lamblia High cysteine membrane protein Group 2 0.0053 0.0078 0.1255
Trichomonas vaginalis proprotein convertase subtilisin/kexin type, putative 0.0027 0.0017 0.0016
Echinococcus multilocularis somatostatin receptor 0.082 0.1936 0.1935
Echinococcus multilocularis beta tubulin 0.0229 0.0504 0.0503
Echinococcus granulosus tubulin subunit beta 0.0229 0.0504 0.0503
Schistosoma mansoni amine GPCR 0.082 0.1936 0.1935
Schistosoma mansoni hypothetical protein 0.0032 0.0028 0.0027
Brugia malayi Eukaryotic aspartyl protease family protein 0.015 0.0313 0.0761
Schistosoma mansoni histamine h1 receptor 0.082 0.1936 0.1935
Trypanosoma brucei heat shock protein, putative 0.0101 0.0196 0.1107
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0104 0.0587
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.2851 0.6853 0.6852
Loa Loa (eye worm) beta-tubulin 0.0229 0.0504 0.2032
Echinococcus granulosus FTZ F1 nuclear receptor protein 0.0026 0.0014 0.0013
Schistosoma mansoni hypothetical protein 0.082 0.1936 0.1935
Schistosoma mansoni rhodopsin-like orphan GPCR 0.082 0.1936 0.1935
Schistosoma mansoni thyroid hormone receptor 0.028 0.0628 0.0627
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0017 0.0016
Loa Loa (eye worm) melatonin receptor type 1A 0.082 0.1936 0.7814
Echinococcus multilocularis g protein coupled receptor 0.082 0.1936 0.1935
Loa Loa (eye worm) hypothetical protein 0.0127 0.0259 0.104
Echinococcus granulosus glutamate receptor ionotropic kainate 3 0.0032 0.0028 0.0027
Brugia malayi AKH receptor 0.082 0.1936 0.4724
Trypanosoma cruzi cruzipain precursor, putative 0.0064 0.0104 0.1082
Onchocerca volvulus 0.082 0.1936 1
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.082 0.1936 0.1935
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0017 0.0016
Brugia malayi hypothetical protein 0.082 0.1936 0.4724
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.0146
Trichomonas vaginalis heat shock protein, putative 0.0101 0.0196 0.1234
Echinococcus granulosus cyclins 0.0064 0.0105 0.0104
Echinococcus multilocularis neuropeptide receptor 0.082 0.1936 0.1935
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Loa Loa (eye worm) calcium/calmodulin-dependent protein kinase ID 0.0068 0.0116 0.0465
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.038 0.2485
Onchocerca volvulus 0.0036 0.0037 0.0122
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.082 0.1936 0.1935
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0146 0.0304 0.3171
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.082 0.1936 0.1935
Brugia malayi nuclear receptor NHR-88 0.0026 0.0014 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0604 0.4016
Echinococcus multilocularis cyclin dependent kinase 1 0.0091 0.0171 0.0169
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.038 0.2485
Echinococcus granulosus COUP TF:Svp nuclear hormone receptor 0.0026 0.0014 0.0013
Schistosoma mansoni neuropeptide receptor 0.082 0.1936 0.1935
Plasmodium falciparum M1-family alanyl aminopeptidase, putative 0.0146 0.0304 0.1968
Brugia malayi Peptidase family M1 containing protein 0.0415 0.0955 0.2329
Echinococcus granulosus serine:threonine protein kinase 0.0268 0.06 0.0599
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0604 0.4016
Brugia malayi larval opioid receptor 0.082 0.1936 0.4724
Trypanosoma cruzi heat shock protein 90, putative 0.0088 0.0164 0.1707
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0104 0.0587
Loa Loa (eye worm) aminopeptidase N 0.0415 0.0955 0.3852
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.015 0.0313 0.0312
Trypanosoma brucei metallo-peptidase, Clan MF, Family M17 0.0105 0.0205 0.116
Trichomonas vaginalis D-aminoacylase, putative 0.0036 0.0037 0.0155
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Toxoplasma gondii ABC1 family protein 0.0036 0.0037 0.0252
Schistosoma mansoni family M1 non-peptidase homologue (M01 family) 0.0269 0.0602 0.0601
Entamoeba histolytica cyclin, putative 0.0127 0.0259 0.2597
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0146 0.0304 0.1968
Onchocerca volvulus 0.082 0.1936 1
Loa Loa (eye worm) proprotein convertase 2 0.0034 0.0032 0.0123
Schistosoma mansoni tyrosine kinase 0.0078 0.0139 0.0138
Loa Loa (eye worm) CMGC/CDK/CDK5 protein kinase 0.0091 0.0171 0.0684
Echinococcus granulosus Nuclear hormone receptor family member nhr 41 0.0026 0.0014 0.0013
Schistosoma mansoni rhodopsin-like orphan GPCR 0.082 0.1936 0.1935
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0014 0.0013
Schistosoma mansoni hypothetical protein 0.0406 0.0934 0.0933
Trypanosoma cruzi cdc2-related kinase 1 0.0091 0.0171 0.1777
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.0203 0.0202
Toxoplasma gondii heat shock protein 75, putative 0.0026 0.0015 0.0098
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0032 0.0116
Schistosoma mansoni glutamate receptor AMPA 0.0032 0.0028 0.0027
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Onchocerca volvulus 0.082 0.1936 1
Schistosoma mansoni rhodopsin-like orphan GPCR 0.082 0.1936 0.1935
Trichomonas vaginalis cyclins, putative 0.0127 0.0259 0.1663
Onchocerca volvulus 0.0036 0.0037 0.0122
Toxoplasma gondii histone lysine methyltransferase SET/SUV39 0.0031 0.0025 0.0168
Brugia malayi hypothetical protein 0.1026 0.2435 0.5942
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0017 0.0016
Schistosoma mansoni heat shock protein 0.0101 0.0196 0.0195
Schistosoma mansoni cathepsin D (A01 family) 0.1867 0.4471 0.447
Loa Loa (eye worm) hypothetical protein 0.0146 0.0304 0.1221
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.027 0.0604 0.1473
Brugia malayi Nuclear hormone receptor-like 1 0.0026 0.0014 0.0031
Echinococcus multilocularis Tubulin beta 2C chain 0.0229 0.0504 0.0503
Trichomonas vaginalis heat shock protein, putative 0.0088 0.0164 0.1018
Onchocerca volvulus 0.0036 0.0037 0.0122
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 2 0.0049 0.0068 0.0067
Mycobacterium tuberculosis Probable glutamine-binding lipoprotein GlnH (GLNBP) 0.0082 0.015 0.0199
Brugia malayi Latrophilin receptor protein 2 0.0177 0.0378 0.092
Trypanosoma cruzi heat shock protein, putative 0.0026 0.0015 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0017 0.0016
Schistosoma mansoni hypothetical protein 0.0254 0.0564 0.0563
Schistosoma mansoni neuropeptide f receptor 76f 0.082 0.1936 0.1935
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0052
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0014 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.082 0.1936 0.1935
Trypanosoma brucei heat shock protein, putative 0.0101 0.0196 0.1107
Brugia malayi Peptidase family M1 containing protein 0.0146 0.0304 0.0738
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0017 0.0016
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0104 0.0587
Echinococcus granulosus g protein coupled receptor 0.082 0.1936 0.1935
Echinococcus multilocularis cyclin dependent kinase 1 0.0091 0.0171 0.0169
Brugia malayi Protein kinase domain containing protein 0.0091 0.0171 0.0414
Echinococcus granulosus tm gpcr rhodopsin 0.082 0.1936 0.1935
Schistosoma mansoni furin-1 (S08 family) 0.0062 0.01 0.0099
Brugia malayi sulfakinin receptor protein 0.1026 0.2435 0.5942
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0604 0.4016
Trypanosoma brucei heat shock protein, putative 0.0101 0.0196 0.1107
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Schistosoma mansoni alpha-1 adrenergic receptor 0.082 0.1936 0.1935
Brugia malayi Melatonin receptor type 1A 0.082 0.1936 0.4724
Echinococcus multilocularis cyclins 0.0064 0.0105 0.0104
Trypanosoma brucei heat shock protein, putative 0.0101 0.0196 0.1107
Echinococcus multilocularis heat shock protein 75 kDa, mitochondrial 0.0026 0.0015 0.0013
Brugia malayi aspartic protease BmAsp-1, identical 0.015 0.0313 0.0761
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0032 0.0116
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.082 0.1936 0.1935
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.082 0.1936 0.1935
Echinococcus granulosus Mitotic checkpoint protein PRCC C terminal 0.0254 0.0564 0.0563
Echinococcus granulosus GPCR family 2 0.0177 0.0378 0.0377
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0146 0.0304 0.0302
Toxoplasma gondii beta tubulin 0.0229 0.0504 0.34
Loa Loa (eye worm) tubulin beta-2A chain 0.0229 0.0504 0.2032
Schistosoma mansoni serine/threonine protein kinase 0.0091 0.0171 0.0169
Brugia malayi G-protein coupled receptor 0.082 0.1936 0.4724
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0104 0.1082
Trichomonas vaginalis cyclin B3, putative 0.0064 0.0105 0.0618
Brugia malayi Cyclin, N-terminal domain containing protein 0.0064 0.0105 0.0254
Schistosoma mansoni tubulin subunit beta 0.0229 0.0504 0.0503
Trypanosoma cruzi cdc2-related kinase 3 0.0091 0.0171 0.1777
Trypanosoma cruzi heat shock protein 85, putative 0.0088 0.0164 0.1707
Schistosoma mansoni leukotriene A4 hydrolase (M01 family) 0.0146 0.0304 0.0302
Mycobacterium leprae Probable cytosol aminopeptidase PepB 0.0105 0.0205 0.0298
Entamoeba histolytica cyclin family protein 0.0064 0.0105 0.0966
Echinococcus multilocularis cyclin B3 1 0.0064 0.0105 0.0104
Echinococcus granulosus glutamate receptor ionotrophic AMPA 3 0.0049 0.0068 0.0067
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.007 0.0119 0.0118
Brugia malayi Tubulin beta-1 chain 0.0229 0.0504 0.1229
Trichomonas vaginalis endoplasmin, putative 0.004 0.0046 0.0217
Echinococcus granulosus cyclin B 0.0127 0.0259 0.0258
Echinococcus multilocularis cyclin dependent kinase 5 0.0091 0.0171 0.0169
Loa Loa (eye worm) TK/INSR protein kinase 0.0047 0.0064 0.0252
Schistosoma mansoni amine GPCR 0.082 0.1936 0.1935
Schistosoma mansoni tyrosine kinase 0.0078 0.0139 0.0138
Echinococcus multilocularis cyclins 0.0064 0.0105 0.0104
Echinococcus multilocularis tubulin, beta 4A class IVa 0.0229 0.0504 0.0503
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0415 0.0955 1
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0146 0.0304 0.3171
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0025 0.0024
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0415 0.0955 0.0954
Loa Loa (eye worm) aspartic protease BmAsp-1 0.015 0.0313 0.1259
Schistosoma mansoni hypothetical protein 0.0177 0.0378 0.0377
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0104 0.0587
Brugia malayi G-protein coupled receptor 0.082 0.1936 0.4724
Plasmodium vivax aspartyl proteinase, putative 0.015 0.0313 0.2031
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0049 0.0068 0.0067
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.0177 0.0378 0.092
Leishmania major cathepsin L-like protease 0.0064 0.0104 0.1082
Loa Loa (eye worm) hypothetical protein 0.0633 0.1484 0.5985
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.0088 0.0164 0.1707
Echinococcus granulosus epidermal growth factor receptor 0.0079 0.0141 0.014
Echinococcus granulosus neuropeptide FF receptor 2 0.082 0.1936 0.1935
Brugia malayi Cyclin, N-terminal domain containing protein 0.0127 0.0259 0.0629
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.082 0.1936 0.4724
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0017 0.0016
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Trypanosoma cruzi cdc2-related kinase 3 0.0091 0.0171 0.1777
Onchocerca volvulus Neuropeptide F receptor homolog 0.082 0.1936 1
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0052
Trichomonas vaginalis alpha-galactosidase/alpha-N-acetylgalactosaminidase, putative 0.007 0.0119 0.071
Trypanosoma brucei heat shock protein 90, putative 0.0101 0.0196 0.1107
Schistosoma mansoni hypothetical protein 0.0177 0.0378 0.0377
Loa Loa (eye worm) glutamate receptor 1 0.0032 0.0028 0.0109
Loa Loa (eye worm) tubulin beta-1 chain 0.0229 0.0504 0.2032
Echinococcus multilocularis FTZ F1 alpha 0.0026 0.0014 0.0013
Wolbachia endosymbiont of Brugia malayi leucyl aminopeptidase 0.0105 0.0205 1
Trichomonas vaginalis Clan MA, family M1, aminopeptidase N-like metallopeptidase 0.0415 0.0955 0.6403
Trypanosoma cruzi beta tubulin, putative 0.0229 0.0504 0.5276
Loa Loa (eye worm) nuclear hormone receptor family member nhr-31 0.0026 0.0014 0.0052
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.082 0.1936 0.1935
Leishmania major protein kinase, putative 0.0068 0.0116 0.1206
Loa Loa (eye worm) CXXC zinc finger family protein 0.0029 0.002 0.0074
Trichomonas vaginalis CAMK family protein kinase 0.0068 0.0116 0.0693
Trichomonas vaginalis tubulin alpha chain, putative 0.0229 0.0504 0.3335
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.082 0.1936 0.1935
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0032 0.0116
Toxoplasma gondii beta-1 tubulin, putative 0.0229 0.0504 0.34
Echinococcus granulosus proprotein convertase subtilisin:kexin type 5 0.0086 0.0159 0.0158
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Plasmodium vivax M17 leucyl aminopeptidase, putative 0.0105 0.0205 0.1298
Schistosoma mansoni hypothetical protein 0.0177 0.0378 0.0377
Echinococcus multilocularis Tubulin beta 2C chain 0.0229 0.0504 0.0503
Trichomonas vaginalis set domain proteins, putative 0.024 0.0531 0.3518
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Schistosoma mansoni myosin xvIII 0.082 0.1936 0.1935
Echinococcus granulosus somatostatin receptor 0.082 0.1936 0.1935
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0032 0.0116
Plasmodium vivax aspartyl proteinase, putative 0.0633 0.1484 1
Brugia malayi putative neuropeptide receptor 0.082 0.1936 0.4724
Schistosoma mansoni glutamate receptor kainate 0.0032 0.0028 0.0027
Toxoplasma gondii calcium-dependent protein kinase CDPK2A 0.0068 0.0116 0.0784
Brugia malayi Nuclear hormone receptor family member nhr-1 0.0026 0.0014 0.0031
Mycobacterium ulcerans glutaminase 0.0273 0.061 0.1017
Entamoeba histolytica heat shock protein 90, putative 0.0101 0.0196 0.1928
Trichomonas vaginalis cyclin B, putative 0.0127 0.0259 0.1663
Echinococcus granulosus rhodopsin orphan GPCR 0.082 0.1936 0.1935
Brugia malayi Serotonin/octopamine receptor family protein 7 0.082 0.1936 0.4724
Echinococcus granulosus dro:myosuppressin receptor 0.082 0.1936 0.1935
Echinococcus multilocularis orexin receptor type 2 0.082 0.1936 0.1935
Echinococcus granulosus 7TM GPCR rhodopsin 0.082 0.1936 0.1935
Toxoplasma gondii aspartyl protease ASP1 0.0633 0.1484 1
Echinococcus granulosus nuclear receptor 2DBD gamma 0.0026 0.0014 0.0013
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Brugia malayi RE15519p 0.082 0.1936 0.4724
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Giardia lamblia Grp94/Hsp90 0.0088 0.0164 0.3018
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0633 0.1484 0.1483
Echinococcus multilocularis glutamate receptor ionotropic kainate 0.0032 0.0028 0.0027
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.0171 0.1063
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.038 0.2485
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Trypanosoma brucei aminopeptidase, putative 0.0146 0.0304 0.1721
Mycobacterium ulcerans leucyl aminopeptidase 0.0105 0.0205 0.0298
Echinococcus granulosus neuropeptides capa receptor 0.082 0.1936 0.1935
Schistosoma mansoni hypothetical protein 0.0382 0.0875 0.0874
Plasmodium vivax calcium-dependent protein kinase 4, putative 0.0068 0.0116 0.0693
Onchocerca volvulus 0.082 0.1936 1
Toxoplasma gondii eukaryotic aspartyl protease superfamily protein 0.015 0.0313 0.2109
Plasmodium falciparum tubulin beta chain 0.0229 0.0504 0.3335
Brugia malayi hypothetical protein 0.082 0.1936 0.4724
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Plasmodium falciparum plasmepsin V 0.015 0.0313 0.2031
Echinococcus multilocularis cyclins 0.0064 0.0105 0.0104
Onchocerca volvulus 0.082 0.1936 1
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.082 0.1936 0.7814
Echinococcus multilocularis GPCR, family 2 0.0177 0.0378 0.0377
Loa Loa (eye worm) hypothetical protein 0.0088 0.0163 0.0655
Mycobacterium ulcerans glutamine-binding lipoprotein GlnH 0.0082 0.015 0.0199
Trypanosoma brucei heat shock protein, putative 0.0101 0.0196 0.1107
Loa Loa (eye worm) beta-lactamase 0.0036 0.0037 0.0146
Trichomonas vaginalis cyclin B, putative 0.0127 0.0259 0.1663
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0146 0.0304 0.3171
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.082 0.1936 0.7814
Plasmodium falciparum cysteine repeat modular protein 1 0.0037 0.004 0.0176
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Echinococcus granulosus cyclins 0.0064 0.0105 0.0104
Toxoplasma gondii cell-cycle-associated protein kinase CDK, putative 0.0091 0.0171 0.1151
Echinococcus granulosus heat shock protein 0.0101 0.0196 0.0195
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.0335 0.0761 0.0759
Schistosoma mansoni heat shock protein 0.0026 0.0015 0.0013
Plasmodium falciparum plasmepsin VII 0.015 0.0313 0.2031
Toxoplasma gondii aspartyl protease ASP3 0.015 0.0313 0.2109
Brugia malayi hypothetical protein 0.015 0.0313 0.0761
Brugia malayi ORL1-like opioid receptor 0.082 0.1936 0.4724
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Echinococcus granulosus epidermal growth factor receptor 0.0146 0.0305 0.0304
Schistosoma mansoni rhodopsin-like orphan GPCR 0.082 0.1936 0.1935
Entamoeba histolytica tubulin family protein 0.0229 0.0504 0.5209
Loa Loa (eye worm) CMGC/CDK/CDC2 protein kinase 0.0091 0.0171 0.0684
Mycobacterium leprae 3-dehydroquinate dehydratase AroD (AroQ) (3-dehydroquinase) (Type II DHQase) 0.2363 0.5671 1
Onchocerca volvulus 0.082 0.1936 1
Trypanosoma cruzi heat shock protein 90, putative 0.0075 0.0132 0.1369
Schistosoma mansoni amine GPCR 0.082 0.1936 0.1935
Schistosoma mansoni tyrosine kinase 0.0079 0.0141 0.014
Loa Loa (eye worm) hypothetical protein 0.0269 0.0602 0.2425
Trypanosoma cruzi hypothetical protein, conserved 0.0037 0.004 0.041
Brugia malayi beta-lactamase family protein 0.0036 0.0037 0.0088
Brugia malayi celfurPC protein 0.0114 0.0227 0.0552
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.0088 0.0164 0.0225
Toxoplasma gondii aminopeptidase N, putative 0.0146 0.0304 0.2047
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0604 0.4016
Plasmodium vivax protein kinase Crk2 0.0091 0.0171 0.1063
Echinococcus granulosus rhodopsin orphan GPCR 0.082 0.1936 0.1935
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Mycobacterium ulcerans aminopeptidase N PepN 0.0415 0.0955 0.1629
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Echinococcus multilocularis rhodopsin orphan GPCR 0.082 0.1936 0.1935
Loa Loa (eye worm) hypothetical protein 0.0269 0.0602 0.2425
Loa Loa (eye worm) hypothetical protein 0.0037 0.004 0.0158
Echinococcus granulosus heat shock protein 90 0.0101 0.0196 0.0195
Echinococcus multilocularis thyroid hormone receptor alpha 0.028 0.0628 0.0627
Schistosoma mansoni tyrosine kinase 0.0047 0.0064 0.0063
Brugia malayi Nuclear hormone receptor family member nhr-41 0.0026 0.0014 0.0031
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0415 0.0955 0.0954
Schistosoma mansoni hypothetical protein 0.082 0.1936 0.1935
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0052
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.0088 0.0164 0.0163
Giardia lamblia Cyclin A 0.0064 0.0105 0.1815
Echinococcus granulosus orexin receptor type 2 0.082 0.1936 0.1935
Toxoplasma gondii histone lysine methyltransferase SET1 0.0055 0.0084 0.0566
Brugia malayi hypothetical protein 0.082 0.1936 0.4724
Schistosoma mansoni subfamily S8B non-peptidase homologue (S08 family) 0.0034 0.0032 0.003
Echinococcus granulosus rhodopsin orphan GPCR 0.082 0.1936 0.1935
Trypanosoma cruzi cysteine peptidase, clan CA, family C1, cathepsin L-like, putative 0.0058 0.0091 0.0942
Loa Loa (eye worm) hypothetical protein 0.0146 0.0304 0.1221
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0415 0.0955 0.0954
Treponema pallidum heat shock protein 90 0.0088 0.0164 1
Echinococcus multilocularis neuroendocrine convertase 2 0.0089 0.0166 0.0165
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.0203 0.0202
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0052
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Echinococcus multilocularis nmda type glutamate receptor 0.0114 0.0227 0.0226
Echinococcus multilocularis 0.0114 0.0227 0.0226
Trypanosoma cruzi heat shock protein 85, putative 0.0101 0.0196 0.2041
Loa Loa (eye worm) G-protein coupled receptor 0.082 0.1936 0.7814
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Schistosoma mansoni glutamate receptor kainate 0.0032 0.0028 0.0027
Schistosoma mansoni mixed-lineage leukemia protein mll 0.0062 0.01 0.0098
Schistosoma mansoni alpha-galactosidase/alpha-n-acetylgalactosaminidase 0.0104 0.0203 0.0202
Brugia malayi G protein-coupled receptor F59B2.13 0.082 0.1936 0.4724
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.038 0.2485
Brugia malayi Peptidase family M1 containing protein 0.0665 0.156 0.3806
Trypanosoma cruzi metallo-peptidase, Clan MA(E) Family M1 0.0269 0.0602 0.6297
Schistosoma mansoni rhodopsin-like orphan GPCR 0.082 0.1936 0.1935
Trypanosoma cruzi CYC2-like cyclin, putative 0.0127 0.0259 0.2701
Schistosoma mansoni nuclear hormone receptor nor-1/nor-2 0.0026 0.0014 0.0013
Echinococcus granulosus sex peptide receptor 0.082 0.1936 0.1935
Trichomonas vaginalis heat shock protein, putative 0.0088 0.0164 0.1018
Brugia malayi neuroendocrine convertase 1 precursor 0.0089 0.0166 0.0403
Schistosoma mansoni aminopeptidase PILS (M01 family) 0.0423 0.0975 0.0974
Plasmodium falciparum calcium-dependent protein kinase 5 0.0068 0.0116 0.0693
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0633 0.1484 0.1483
Onchocerca volvulus 0.0127 0.0259 0.1274
Trypanosoma brucei mitotic cyclin 6 0.0127 0.0259 0.1466
Schistosoma mansoni biogenic amine (dopamine) receptor 0.082 0.1936 0.1935
Trichomonas vaginalis hypothetical protein 0.0027 0.0017 0.0016
Brugia malayi beta-lactamase family protein 0.0036 0.0037 0.0088
Echinococcus granulosus allatostatin A receptor 0.082 0.1936 0.1935
Plasmodium vivax hypothetical protein, conserved 0.0036 0.0037 0.0155
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Plasmodium falciparum M1-family alanyl aminopeptidase 0.0146 0.0304 0.1968
Schistosoma mansoni serine/threonine protein kinase 0.0068 0.0116 0.0115
Trypanosoma cruzi cysteine peptidase, putative 0.0064 0.0104 0.1082
Echinococcus granulosus G protein coupled receptor 139 0.082 0.1936 0.1935
Echinococcus granulosus glutamate NMDA receptor subunit 0.0271 0.0606 0.0605
Schistosoma mansoni biogenic amine (5HT) receptor 0.082 0.1936 0.1935
Brugia malayi latrophilin 2 splice variant baaae 0.0382 0.0875 0.2132
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Leishmania major puromycin-sensitive aminopeptidase-like protein,metallo-peptidase, Clan MA(E), Family M1 0.0146 0.0304 0.3171
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0104 0.0587
Echinococcus granulosus aminopeptidase N 0.0665 0.156 0.1559
Entamoeba histolytica heat shock protein 90, putative 0.0101 0.0196 0.1928
Loa Loa (eye worm) hypothetical protein 0.0031 0.0025 0.0096
Brugia malayi Nuclear hormone receptor family member nhr-49 0.0026 0.0014 0.0031
Brugia malayi Nuclear hormone receptor family member nhr-19 0.0026 0.0014 0.0031
Schistosoma mansoni amine GPCR 0.082 0.1936 0.1935
Echinococcus multilocularis myosin light chain kinase, smooth muscle 0.0268 0.06 0.0599
Onchocerca volvulus 0.082 0.1936 1
Echinococcus multilocularis neuropeptides capa receptor 0.082 0.1936 0.1935
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0146 0.0304 0.0302
Plasmodium falciparum plasmepsin IX 0.015 0.0313 0.2031
Giardia lamblia Hypothetical protein 0.0064 0.0105 0.1815
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0017 0.0016
Trichomonas vaginalis tubulin epsilon chain, putative 0.0229 0.0504 0.3335
Schistosoma mansoni growth hormone secretagogue receptor 0.082 0.1936 0.1935
Trichomonas vaginalis tubulin gamma chain, putative 0.0229 0.0504 0.3335
Echinococcus granulosus Furin 1 0.0034 0.0032 0.003
Echinococcus granulosus cyclin dependent kinase 0.0091 0.0171 0.0169
Echinococcus multilocularis tissue type plasminogen activator 0.0037 0.004 0.0039
Onchocerca volvulus 0.082 0.1936 1
Echinococcus multilocularis leucine aminopeptidase protein 0.0105 0.0205 0.0204
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0269 0.0602 0.0601
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0104 0.0587
Trichomonas vaginalis cyclin B, putative 0.0127 0.0259 0.1663
Echinococcus granulosus cyclins 0.0064 0.0105 0.0104
Brugia malayi Endoplasmin precursor 0.0101 0.0196 0.0475
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0415 0.0955 0.0954
Plasmodium vivax calcium-dependent protein kinase, putative 0.0068 0.0116 0.0693
Echinococcus granulosus retinoic acid receptor rxr beta a 0.0026 0.0014 0.0013
Echinococcus granulosus alpha 1A adrenergic receptor 0.082 0.1936 0.1935
Leishmania major cyclin 0.0127 0.0259 0.2701
Echinococcus granulosus 5'partial|cyclin dependent kinase 1 0.0091 0.0171 0.0169
Trichomonas vaginalis heat shock protein, putative 0.004 0.0046 0.0217
Brugia malayi Ligand-binding domain of nuclear hormone receptor family protein 0.0026 0.0014 0.0031
Echinococcus multilocularis COUP TF:Svp nuclear hormone receptor 0.0026 0.0014 0.0013
Brugia malayi neuropeptide F receptor 0.082 0.1936 0.4724
Onchocerca volvulus 0.0415 0.0955 0.4895
Echinococcus multilocularis heat shock protein 90 0.0101 0.0196 0.0195
Leishmania major hypothetical protein, conserved 0.0037 0.004 0.041
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.055 0.1283 0.1282
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0403 0.2642
Brugia malayi GnHR receptor homolog 0.1713 0.4098 1
Loa Loa (eye worm) endoplasmin 0.0101 0.0196 0.0786
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Plasmodium falciparum plasmepsin I 0.0633 0.1484 1
Onchocerca volvulus 0.082 0.1936 1
Echinococcus multilocularis dro:myosuppressin receptor 0.082 0.1936 0.1935
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.015 0.0313 0.0312
Brugia malayi hypothetical protein 0.082 0.1936 0.4724
Trypanosoma brucei heat shock protein, putative 0.0101 0.0196 0.1107
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.082 0.1936 0.1935
Schistosoma mansoni neuropeptide F-like receptor 0.082 0.1936 0.1935
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Echinococcus multilocularis Tubulin beta 2C chain 0.0229 0.0504 0.0503
Brugia malayi photoreceptor-specific nuclear receptor 0.0026 0.0014 0.0031
Toxoplasma gondii Hsp90 domain-containing protein 0.0026 0.0015 0.0098
Giardia lamblia Heat shock protein HSP 90-alpha 0.0101 0.0196 0.3671
Echinococcus multilocularis leukotriene A 4 hydrolase 0.0146 0.0304 0.0302
Loa Loa (eye worm) nuclear Hormone Receptor family member 0.0026 0.0014 0.0052
Brugia malayi gonadotropin-releasing hormone receptor 2 0.082 0.1936 0.4724
Loa Loa (eye worm) hypothetical protein 0.0177 0.0378 0.1523
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Brugia malayi hypothetical protein 0.082 0.1936 0.4724
Brugia malayi Pepsin A precursor 0.015 0.0313 0.0761
Plasmodium falciparum plasmepsin VIII, putative 0.015 0.0313 0.2031
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.082 0.1936 0.1935
Schistosoma mansoni neuropeptide receptor 0.4151 1 1
Loa Loa (eye worm) hypothetical protein 0.0142 0.0294 0.1182
Echinococcus multilocularis neuropeptide receptor A26 0.082 0.1936 0.1935
Schistosoma mansoni tubulin subunit beta 0.0229 0.0504 0.0503
Echinococcus multilocularis cyclin B 0.0127 0.0259 0.0258
Schistosoma mansoni cpg binding protein 0.0029 0.002 0.0018
Echinococcus multilocularis Peptidase M1, membrane alanine aminopeptidase, N terminal 0.0415 0.0955 0.0954
Onchocerca volvulus 0.082 0.1936 1
Echinococcus granulosus hepatocyte nuclear factor 4 alpha 0.0026 0.0014 0.0013
Plasmodium vivax calcium-dependent protein kinase 3, putative 0.0068 0.0116 0.0693
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0415 0.0955 0.0954
Trichomonas vaginalis heat shock protein, putative 0.0088 0.0164 0.1018
Echinococcus granulosus neuropeptide receptor A26 0.082 0.1936 0.1935
Giardia lamblia Heat shock protein HSP 90-alpha 0.0088 0.0164 0.3018
Echinococcus multilocularis calcium:calmodulin dependent protein kinase type 0.055 0.1283 0.1282
Brugia malayi Hypothetical 52.5 kDa protein ZK945.1 in chromosome II, putative 0.0036 0.0037 0.0088
Schistosoma mansoni cpg binding protein 0.003 0.0023 0.0022
Toxoplasma gondii hypothetical protein 0.0049 0.0068 0.0458
Trichomonas vaginalis glutaminase, putative 0.0273 0.061 0.4055
Echinococcus granulosus neuropeptide s receptor 0.082 0.1936 0.1935
Trypanosoma cruzi Heat shock protein 83, putative 0.0101 0.0196 0.2041
Echinococcus granulosus rhodopsin orphan GPCR 0.082 0.1936 0.1935
Brugia malayi Calcium/calmodulin-dependent protein kinase type II alpha chain 0.0482 0.1117 0.2724
Toxoplasma gondii heat shock protein 90, putative 0.0101 0.0196 0.132
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Schistosoma mansoni opsin-like receptor 0.082 0.1936 0.1935
Brugia malayi Glutamate receptor 2 precursor 0.0032 0.0028 0.0066
Loa Loa (eye worm) BEN-1 protein 0.0229 0.0504 0.2032
Brugia malayi follicle stimulating hormone receptor 0.1044 0.2478 0.6046
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0086 0.0159 0.0985
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Echinococcus granulosus tm gpcr rhodopsin 0.2851 0.6853 0.6852
Schistosoma mansoni biogenic amine receptor 0.082 0.1936 0.1935
Schistosoma mansoni cyclins 0.0064 0.0105 0.0104
Brugia malayi Serotonin receptor 0.082 0.1936 0.4724
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Brugia malayi hypothetical protein 0.015 0.0313 0.0761
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.082 0.1936 0.1935
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0086 0.0159 0.0985
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Schistosoma mansoni glutamate receptor kainate 0.0032 0.0028 0.0027
Trichomonas vaginalis glucosylceramidase, putative 0.0187 0.0403 0.2642
Echinococcus granulosus cyclins 0.0064 0.0105 0.0104
Schistosoma mansoni cathepsin D (A01 family) 0.1867 0.4471 0.447
Echinococcus multilocularis cyclin b3 0.0064 0.0105 0.0104
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Plasmodium vivax aspartyl protease, putative 0.015 0.0313 0.2031
Loa Loa (eye worm) G-protein coupled receptor 0.082 0.1936 0.7814
Plasmodium vivax aspartyl protease, putative 0.015 0.0313 0.2031
Onchocerca volvulus 0.0031 0.0025 0.0057
Loa Loa (eye worm) neuropeptide F receptor 0.082 0.1936 0.7814
Loa Loa (eye worm) pigment dispersing factor receptor c 0.0559 0.1303 0.5255
Echinococcus multilocularis nuclear receptor 2DBD gamma 0.0026 0.0014 0.0013
Echinococcus multilocularis cyclin dependent kinase 0.0091 0.0171 0.0169
Echinococcus granulosus biogenic amine 5HT receptor 0.082 0.1936 0.1935
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.082 0.1936 0.1935
Brugia malayi Protein kinase domain containing protein 0.0047 0.0064 0.0153
Echinococcus granulosus Tubulin beta 2C chain 0.0229 0.0504 0.0503
Echinococcus multilocularis rhodopsin orphan GPCR 0.082 0.1936 0.1935
Mycobacterium tuberculosis Probable aminopeptidase PepB 0.0105 0.0205 0.0298
Trypanosoma cruzi puromycin-sensitive aminopeptidase-like protein, putative 0.0146 0.0304 0.3171
Onchocerca volvulus 0.082 0.1936 1
Echinococcus multilocularis Glutamate receptor, ionotropic kainate 3 0.0114 0.0227 0.0226
Echinococcus multilocularis serine:threonine protein kinase 0.0268 0.06 0.0599
Echinococcus granulosus dnaJ subfamily B 0.0406 0.0934 0.0933
Loa Loa (eye worm) hypothetical protein 0.0026 0.0014 0.0052
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0415 0.0955 0.0954
Brugia malayi Nuclear hormone receptor family member nhr-3 0.0026 0.0014 0.0031
Echinococcus granulosus beta tubulin 0.0229 0.0504 0.0503
Echinococcus multilocularis calcium dependent protein kinase 0.0065 0.0109 0.0108
Echinococcus multilocularis biogenic amine (5HT) receptor 0.082 0.1936 0.1935
Echinococcus granulosus puromycin sensitive aminopeptidase 0.0415 0.0955 0.0954
Schistosoma mansoni opsin-like receptor 0.082 0.1936 0.1935
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Echinococcus multilocularis tachykinin peptides receptor 99D 0.082 0.1936 0.1935
Schistosoma mansoni amine GPCR 0.082 0.1936 0.1935
Trypanosoma brucei calcium/calmodulin-dependent protein kinase, putative 0.0068 0.0116 0.0655
Onchocerca volvulus 0.082 0.1936 1
Echinococcus granulosus Glutamate receptor ionotropic kainate 2 0.0049 0.0068 0.0067
Trichomonas vaginalis Clan SB, family S8, subtilisin-like serine peptidase 0.0034 0.0032 0.0116
Trypanosoma brucei RNA helicase, putative 0.0747 0.1759 1
Schistosoma mansoni hypothetical protein 0.082 0.1936 0.1935
Echinococcus granulosus cyclin b3 0.0064 0.0105 0.0104
Brugia malayi Dopamine receptor protein 1 0.082 0.1936 0.4724
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0017 0.0016
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0037 0.0379
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0633 0.1484 1
Echinococcus multilocularis puromycin sensitive aminopeptidase 0.0415 0.0955 0.0954
Loa Loa (eye worm) hypothetical protein 0.015 0.0313 0.1259
Leishmania major cell division protein kinase 2,cdc2-related kinase 0.0091 0.0171 0.1777
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Schistosoma mansoni neuropeptide receptor 0.082 0.1936 0.1935
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0633 0.1484 1
Trypanosoma brucei heat shock protein 84, putative 0.0026 0.0015 0.0076
Trypanosoma brucei beta tubulin 0.0229 0.0504 0.2863
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.038 0.2485
Loa Loa (eye worm) follicle stimulating hormone receptor 0.1044 0.2478 1
Echinococcus granulosus hypothetical protein 0.082 0.1936 0.1935
Brugia malayi heat shock protein 90 0.0101 0.0196 0.0475
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Echinococcus multilocularis fmrfamide receptor 0.082 0.1936 0.1935
Brugia malayi putative neuropeptide receptor NPR1 0.082 0.1936 0.4724
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.0629 0.1473 0.5942
Onchocerca volvulus 0.0665 0.156 0.8044
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Loa Loa (eye worm) heat shock protein 75 0.0026 0.0015 0.0054
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Chlamydia trachomatis cytosol aminopeptidase 0.0105 0.0205 1
Entamoeba histolytica cyclin family protein 0.0064 0.0105 0.0966
Leishmania major beta tubulin 0.0229 0.0504 0.5276
Echinococcus multilocularis neuropeptide Y receptor 0.082 0.1936 0.1935
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Onchocerca volvulus 0.0146 0.0304 0.1507
Schistosoma mansoni Tata binding protein associated factor (M01 family) 0.0146 0.0304 0.0302
Trypanosoma cruzi heat shock protein 90, putative 0.0101 0.0196 0.2041
Echinococcus multilocularis glutamate receptor, ionotrophic, AMPA 3 0.0049 0.0068 0.0067
Trypanosoma cruzi hypothetical protein, conserved 0.0036 0.0037 0.0379
Schistosoma mansoni cyclin B 0.0127 0.0259 0.0258
Trichomonas vaginalis neuroendocrine convertase 2 precursor, putative 0.0027 0.0017 0.0016
Echinococcus granulosus tm gpcr rhodopsin 0.082 0.1936 0.1935
Schistosoma mansoni histone-lysine n-methyltransferase setb1 0.0031 0.0025 0.0024
Trichomonas vaginalis glucosylceramidase, putative 0.0177 0.038 0.2485
Loa Loa (eye worm) glutaminase 2 0.0273 0.061 0.2459
Giardia lamblia Kinase, CMGC CDK 0.0091 0.0171 0.3154
Trichomonas vaginalis CMGC family protein kinase 0.0091 0.0171 0.1063
Echinococcus multilocularis heat shock protein 0.0101 0.0196 0.0195
Loa Loa (eye worm) hypothetical protein 0.0056 0.0085 0.0339
Trichomonas vaginalis cyclins, putative 0.0127 0.0259 0.1663
Echinococcus multilocularis alpha 1A adrenergic receptor 0.082 0.1936 0.1935
Echinococcus granulosus histone lysine methyltransferase setb 0.0031 0.0025 0.0024
Mycobacterium ulcerans aminopeptidase N PepN 0.0146 0.0304 0.0473
Loa Loa (eye worm) hypothetical protein 0.007 0.0119 0.0475
Trypanosoma brucei metallo-peptidase, Clan MA(E) Family M1 0.0415 0.0955 0.5427
Brugia malayi Pre-SET motif family protein 0.0031 0.0025 0.0058
Brugia malayi glutaminase DH11.1 0.0273 0.061 0.1487
Brugia malayi TATA binding protein associated factor 0.0146 0.0304 0.0738
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.082 0.1936 0.1935
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.015 0.0313 0.0312
Trypanosoma cruzi cyclin, putative 0.0127 0.0259 0.2701
Toxoplasma gondii kringle domain-containing protein 0.0037 0.004 0.0272
Echinococcus granulosus serotonin receptor 0.082 0.1936 0.1935
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.0335 0.0761 0.0759
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0017 0.0016
Loa Loa (eye worm) hypothetical protein 0.0068 0.0116 0.0465
Trypanosoma brucei cysteine peptidase, Clan CA, family C1, Cathepsin L-like 0.0064 0.0104 0.0587
Plasmodium falciparum plasmepsin III 0.015 0.0313 0.2031
Echinococcus multilocularis serotonin receptor 0.082 0.1936 0.1935
Brugia malayi Dopamine receptor protein 2 0.082 0.1936 0.4724
Brugia malayi proprotein convertase 2 0.0089 0.0166 0.0403
Trypanosoma cruzi cyclin, putative 0.0127 0.0259 0.2701
Schistosoma mansoni hypothetical protein 0.0747 0.1759 0.1758
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0604 0.4016
Brugia malayi Melibiase family protein 0.007 0.0119 0.0287
Trypanosoma cruzi metallo-peptidase, clan MA(E), family M1, putative 0.0415 0.0955 1
Echinococcus granulosus glutamate receptor 2 0.0049 0.0068 0.0067
Trypanosoma cruzi heat shock protein 85, putative 0.0101 0.0196 0.2041
Onchocerca volvulus 0.082 0.1936 1
Trypanosoma brucei heat shock protein 90, putative 0.0101 0.0196 0.1107
Schistosoma mansoni tubulin subunit beta 0.0229 0.0504 0.0503
Plasmodium falciparum endoplasmin, putative 0.004 0.0046 0.0217
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.082 0.1936 0.1935
Trichomonas vaginalis cyclin B, putative 0.0064 0.0105 0.0618
Loa Loa (eye worm) heat shock protein 90 0.0101 0.0196 0.0786
Loa Loa (eye worm) aspartyl protease 6 0.015 0.0313 0.1259
Loa Loa (eye worm) cyclin domain-containing protein 0.0064 0.0105 0.0421
Giardia lamblia Beta tubulin 0.0229 0.0504 1
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.082 0.1936 0.1935
Trichomonas vaginalis esterase, putative 0.0036 0.0037 0.0155
Echinococcus multilocularis Nuclear hormone receptor family member nhr 41 0.0026 0.0014 0.0013
Echinococcus multilocularis FTZ F1 nuclear receptor protein 0.0026 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Schistosoma mansoni tubulin subunit beta 0.0229 0.0504 0.0503
Brugia malayi Tachykinin-like peptides receptor 99D 0.082 0.1936 0.4724
Plasmodium vivax endoplasmin, putative 0.0101 0.0196 0.1234
Schistosoma mansoni nuclear hormone receptor 0.0026 0.0014 0.0013
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Schistosoma mansoni tyrosine kinase 0.0079 0.0141 0.014
Brugia malayi Nuclear hormone receptor family member nhr-14 0.0026 0.0014 0.0031
Echinococcus multilocularis proprotein convertase subtilisin:kexin type 5 0.0086 0.0159 0.0158
Echinococcus granulosus glutamate receptor subunit protein glur 0.0032 0.0028 0.0027
Echinococcus multilocularis tubulin beta 1 chain 0.0229 0.0504 0.0503
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Loa Loa (eye worm) hypothetical protein 0.1026 0.2435 0.9828
Echinococcus multilocularis serotonin receptor 0.082 0.1936 0.1935
Echinococcus multilocularis 0.0045 0.006 0.0059
Echinococcus multilocularis tubulin subunit beta 0.0229 0.0504 0.0503
Plasmodium falciparum protein kinase 5 0.0091 0.0171 0.1063
Schistosoma mansoni protein kinase 0.055 0.1283 0.1282
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0633 0.1484 0.5985
Schistosoma mansoni endoplasmin 0.0101 0.0196 0.0195
Echinococcus multilocularis allatostatin A receptor 0.082 0.1936 0.1935
Echinococcus granulosus tubulin beta 4A class IVa 0.0229 0.0504 0.0503
Loa Loa (eye worm) CAMK/CAMK2 protein kinase 0.0068 0.0116 0.0465
Mycobacterium ulcerans 3-dehydroquinate dehydratase 0.2363 0.5671 1
Brugia malayi endoprotease bli-4 precursor 0.0142 0.0294 0.0714
Giardia lamblia G2/mitotic-specific cyclin B 0.0127 0.0259 0.4962
Echinococcus multilocularis cyclins 0.0064 0.0105 0.0104
Echinococcus granulosus calcium:calmodulin dependent protein kinase type 0.0068 0.0116 0.0115
Leishmania major cathepsin L-like protease 0.0064 0.0104 0.1082
Echinococcus multilocularis beta LACTamase domain containing family member 0.0036 0.0037 0.0036
Loa Loa (eye worm) hypothetical protein 0.082 0.1936 0.7814
Echinococcus granulosus neuropeptide Y receptor 0.082 0.1936 0.1935
Echinococcus multilocularis Tubulin beta 2C chain 0.0229 0.0504 0.0503
Leishmania major aminopeptidase, putative,metallo-peptidase, Clan MA(E), Family M1 0.0146 0.0304 0.3171
Schistosoma mansoni neuropeptide receptor 0.082 0.1936 0.1935
Brugia malayi Calcitonin receptor-like protein seb-1 0.0559 0.1303 0.3177
Loa Loa (eye worm) hypothetical protein 0.0036 0.0037 0.0146
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0633 0.1484 0.1483
Trichomonas vaginalis tubulin epsilon chain, putative 0.0229 0.0504 0.3335
Schistosoma mansoni tyrosine kinase 0.0078 0.0139 0.0138
Schistosoma mansoni hypothetical protein 0.082 0.1936 0.1935
Leishmania major heat shock protein 83-1 0.0101 0.0196 0.2041
Echinococcus granulosus g-protein coupled receptor 0.082 0.1936 0.1935
Trichomonas vaginalis cyclins, putative 0.0127 0.0259 0.1663
Echinococcus multilocularis neuropeptides capa receptor 0.082 0.1936 0.1935
Plasmodium falciparum M17 leucyl aminopeptidase 0.0105 0.0205 0.1298
Echinococcus granulosus beta LACTamase domain containing family member 0.0036 0.0037 0.0036
Echinococcus multilocularis rhodopsin orphan GPCR 0.082 0.1936 0.1935
Brugia malayi Glutamate receptor 1 precursor 0.0032 0.0028 0.0066
Plasmodium vivax SET domain protein, putative 0.0031 0.0025 0.0071
Echinococcus multilocularis Mitotic checkpoint protein PRCC, C terminal 0.0254 0.0564 0.0563
Schistosoma mansoni biogenic amine receptor 0.082 0.1936 0.1935
Echinococcus multilocularis G2:mitotic specific cyclin B3 0.0064 0.0105 0.0104
Trichomonas vaginalis cyclins, putative 0.0127 0.0259 0.1663
Echinococcus multilocularis neuropeptide receptor 0.4151 1 1
Plasmodium vivax M1-family alanyl aminopeptidase, putative 0.0146 0.0304 0.1968
Toxoplasma gondii melibiase subfamily protein 0.0104 0.0203 0.1367
Mycobacterium ulcerans heat shock protein 90 0.0088 0.0164 0.0225
Trichomonas vaginalis tubulin, putative 0.0229 0.0504 0.3335
Trichomonas vaginalis leucine-rich repeat protein, BspA family 0.0027 0.0017 0.0016
Schistosoma mansoni biogenic amine receptor 0.082 0.1936 0.1935
Trypanosoma brucei Aminopeptidase M1, putative 0.0415 0.0955 0.5427
Echinococcus granulosus Tubulin beta 2C chain 0.0229 0.0504 0.0503
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.082 0.1936 0.1935
Giardia lamblia Kinase, CMGC CDK 0.0091 0.0171 0.3154
Trichomonas vaginalis conserved hypothetical protein 0.0027 0.0017 0.0016
Toxoplasma gondii aminopeptidase n, putative 0.0146 0.0304 0.2047
Echinococcus granulosus cyclin B3 1 0.0064 0.0105 0.0104
Echinococcus multilocularis fmrfamide receptor 0.082 0.1936 0.1935
Echinococcus multilocularis rhodopsin orphan GPCR 0.082 0.1936 0.1935
Schistosoma mansoni tubulin subunit beta 0.0229 0.0504 0.0503
Brugia malayi hypothetical protein 0.0415 0.0955 0.2329
Plasmodium vivax calcium-dependent protein kinase 1, putative 0.0068 0.0116 0.0693
Loa Loa (eye worm) endoprotease bli-4 0.0142 0.0294 0.1182
Trichomonas vaginalis glucosylceramidase, putative 0.027 0.0604 0.4016
Echinococcus multilocularis heat shock protein 90 0.0088 0.0164 0.0163
Brugia malayi hypothetical protein 0.0146 0.0304 0.0738
Brugia malayi Nuclear hormone receptor family member nhr-25 0.0026 0.0014 0.0031

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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