Detailed information for compound 805248

Basic information

Technical information
  • TDR Targets ID: 805248
  • Name: N-(4-fluorophenyl)-1-methylsulfanyl-9,10-diox oanthracene-2-carboxamide
  • MW: 391.415 | Formula: C22H14FNO3S
  • H donors: 1 H acceptors: 3 LogP: 4.31 Rotable bonds: 4
    Rule of 5 violations (Lipinski): 1
  • SMILES: CSc1c(ccc2c1C(=O)c1ccccc1C2=O)C(=O)Nc1ccc(cc1)F
  • InChi: 1S/C22H14FNO3S/c1-28-21-17(22(27)24-13-8-6-12(23)7-9-13)11-10-16-18(21)20(26)15-5-3-2-4-14(15)19(16)25/h2-11H,1H3,(H,24,27)
  • InChiKey: VAQHGWRTKVMCII-UHFFFAOYSA-N  


Substructure search Similarity search

Network

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Synonyms

  • N-(4-fluorophenyl)-1-methylsulfanyl-9,10-dioxo-anthracene-2-carboxamide
  • N-(4-fluorophenyl)-1-(methylthio)-9,10-dioxo-2-anthracenecarboxamide
  • N-(4-fluorophenyl)-9,10-diketo-1-(methylthio)anthracene-2-carboxamide
  • Anthracene-2-carboxylic acid, 1-methylsulfanyl-9,10-dioxo-9,10-dihydro-, (4-fluorophenyl)amide
  • A3500/0148370
  • ZINC04689416

Targets

Known targets for this compound

No curated genes were found associated with this compound

Predicted pathogen targets for this compound

By orthology
No druggable targets predicted by orthology data
By sequence similarity to non orthologous known druggable targets
No druggable targets predicted by sequence similarity
Obtained from network model

Ranking Plot

Putative Targets List

Species Potential target Raw Global Species
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0048 0.0392
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1201 0.1434 0.2455
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0088 0.0074 0.0604
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Echinococcus multilocularis SWI:SNF matrix associated 0.0042 0.0018 0.0031
Brugia malayi Armadillo/beta-catenin-like repeat family protein 0.0187 0.0195 0.0195
Onchocerca volvulus 0.1201 0.1434 0.5687
Brugia malayi Thioredoxin reductase 0.0062 0.0043 0.0043
Echinococcus granulosus g protein coupled receptor 0.1201 0.1434 0.2455
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Trichomonas vaginalis endoplasmin, putative 0.0041 0.0017 0.0134
Echinococcus multilocularis Tubulin beta 2C chain 0.1035 0.123 0.2107
Brugia malayi RE15519p 0.1201 0.1434 0.1434
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1201 0.1434 0.2617
Echinococcus granulosus neuropeptides capa receptor 0.1201 0.1434 0.2455
Onchocerca volvulus 0.1201 0.1434 0.5687
Entamoeba histolytica heat shock protein 90, putative 0.0143 0.0142 0.1151
Trypanosoma brucei serine peptidase, clan SC, family S9A-like protein 0.0056 0.0035 0.0282
Echinococcus multilocularis tachykinin peptides receptor 99D 0.1201 0.1434 0.2455
Brugia malayi hypothetical protein 0.1627 0.1954 0.1954
Echinococcus multilocularis 0.0035 0.0009 0.0016
Echinococcus granulosus 14-3-3 protein 0.0035 0.0009 0.0016
Echinococcus multilocularis diuretic hormone 44 receptor GPRdih2 0.095 0.1127 0.1929
Echinococcus granulosus 14-3-3 protein gamma 0.0035 0.0009 0.0016
Schistosoma mansoni hypothetical protein 0.1201 0.1434 0.2617
Trichomonas vaginalis heat shock protein, putative 0.0143 0.0142 0.1151
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Leishmania major beta tubulin 0.1035 0.123 1
Onchocerca volvulus 0.1201 0.1434 0.5687
Brugia malayi follicle stimulating hormone receptor 0.213 0.2567 0.2567
Schistosoma mansoni muscarinic acetylcholine (GAR) receptor 0.1201 0.1434 0.2617
Trypanosoma brucei heat shock protein, putative 0.0143 0.0142 0.1151
Entamoeba histolytica protein kinase, putative 0.0041 0.0017 0.014
Plasmodium falciparum cysteine repeat modular protein 4 0.0041 0.0017 0.014
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.1201 0.1434 0.2617
Echinococcus multilocularis heat shock protein 90 0.013 0.0125 0.0214
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0285 0.2318
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1201 0.1434 0.2617
Echinococcus granulosus neuropeptides capa receptor 0.1201 0.1434 0.2455
Echinococcus granulosus thyrotropin releasing hormone receptor 0.1201 0.1434 0.2455
Echinococcus granulosus beta tubulin 0.1035 0.123 0.2107
Onchocerca volvulus 0.1201 0.1434 0.5687
Brugia malayi GCC2 and GCC3 family protein 0.0041 0.0017 0.0017
Schistosoma mansoni endoplasmin 0.0143 0.0142 0.0258
Brugia malayi Calcitonin receptor-like protein seb-1 0.2967 0.359 0.359
Leishmania major beta tubulin 0.1035 0.123 1
Trichomonas vaginalis heat shock protein, putative 0.0041 0.0017 0.0134
Giardia lamblia CEGP1 protein 0.0041 0.0017 0.0066
Onchocerca volvulus 0.1201 0.1434 0.5687
Schistosoma mansoni neuropeptide receptor 0.1201 0.1434 0.2617
Brugia malayi putative neuropeptide receptor NPR1 0.1201 0.1434 0.1434
Brugia malayi Tubulin beta-1 chain 0.1035 0.123 0.123
Echinococcus granulosus biogenic amine 5HT receptor 0.1201 0.1434 0.2455
Plasmodium vivax plasmepsin IV, putative 0.0099 0.0088 0.0713
Plasmodium falciparum plasmepsin I 0.0099 0.0088 0.0713
Echinococcus multilocularis rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Plasmodium vivax heat shock protein 86, putative 0.0143 0.0142 0.1151
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Entamoeba histolytica hypothetical protein 0.0041 0.0017 0.014
Trichomonas vaginalis tubulin gamma chain, putative 0.1035 0.123 1
Loa Loa (eye worm) G-protein coupled receptor 0.1201 0.1434 0.3994
Toxoplasma gondii aspartyl proteinase (eimepsin), putative 0.0099 0.0088 0.0713
Echinococcus granulosus tubulin subunit beta 0.1035 0.123 0.2107
Loa Loa (eye worm) tyrosyl-DNA phosphodiesterase 0.0067 0.0048 0.0134
Echinococcus granulosus ephrin type A receptor 4 A 0.0217 0.0232 0.0396
Echinococcus multilocularis 14-3-3 protein zeta:delta 0.0035 0.0009 0.0016
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Toxoplasma gondii Adenosine/AMP deaminase domain-containing protein 0.0088 0.0074 0.0604
Trypanosoma cruzi heat shock protein 85, putative 0.0143 0.0142 0.1151
Brugia malayi Serotonin/octopamine receptor family protein 7 0.1201 0.1434 0.1434
Loa Loa (eye worm) hypothetical protein 0.0052 0.003 0.0084
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0176 0.1428
Loa Loa (eye worm) beta-tubulin 0.1035 0.123 0.3428
Leishmania major beta tubulin 0.1035 0.123 1
Trichomonas vaginalis glutaminase, putative 0.0294 0.0326 0.2646
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0017 0.014
Trichomonas vaginalis conserved hypothetical protein 0.0042 0.0018 0.0148
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.1201 0.1434 0.2455
Echinococcus multilocularis rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Entamoeba histolytica cysteine-rich surface protein, putative 0.0041 0.0017 0.014
Brugia malayi hypothetical protein 0.1201 0.1434 0.1434
Entamoeba histolytica tubulin family protein 0.1035 0.123 1
Echinococcus granulosus tm gpcr rhodopsin 0.1201 0.1434 0.2455
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Loa Loa (eye worm) heat shock protein 90 0.0143 0.0142 0.0394
Schistosoma mansoni opsin-like receptor 0.1201 0.1434 0.2617
Loa Loa (eye worm) G-protein-linked acetylcholine receptor protein 2 0.1201 0.1434 0.3994
Schistosoma mansoni amine GPCR 0.1201 0.1434 0.2617
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0285 0.2318
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Brugia malayi G protein-coupled receptor F59B2.13 0.1201 0.1434 0.1434
Leishmania major adenosine monophosphate deaminase, putative,AMP deaminase, putative 0.0029 0.0002 0.0015
Brugia malayi Serotonin receptor 0.1201 0.1434 0.1434
Loa Loa (eye worm) hypothetical protein 0.0035 0.0009 0.0026
Trichomonas vaginalis heat shock protein, putative 0.013 0.0125 0.1017
Echinococcus multilocularis rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Wolbachia endosymbiont of Brugia malayi heat shock protein 90 0.013 0.0125 0.5
Leishmania major lipophosphoglycan biosynthetic protein, putative,heat shock protein 90, putative,glucose regulated protein 94, putative 0.013 0.0125 0.1017
Leishmania major beta tubulin 0.1035 0.123 1
Schistosoma mansoni neuropeptide receptor 0.4514 0.5479 1
Echinococcus multilocularis rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Echinococcus granulosus Upstream activation factor subunit UAF30 0.0042 0.0018 0.0031
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0176 0.1428
Schistosoma mansoni amine GPCR 0.1201 0.1434 0.2617
Loa Loa (eye worm) BEN-1 protein 0.1035 0.123 0.3428
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.1201 0.1434 0.2455
Brugia malayi ephrin receptor 1 precursor 0.0084 0.0069 0.0069
Onchocerca volvulus 0.0174 0.0179 0.0709
Echinococcus granulosus neuropeptide FF receptor 2 0.1201 0.1434 0.2455
Trypanosoma cruzi hypothetical protein, conserved 0.003 0.0003 0.0024
Brugia malayi hypothetical protein 0.1201 0.1434 0.1434
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Leishmania major beta tubulin 0.1035 0.123 1
Brugia malayi Serotonin receptor 0.1201 0.1434 0.1434
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0042 0.0018 0.0148
Loa Loa (eye worm) thioredoxin reductase 0.0062 0.0043 0.012
Echinococcus multilocularis orexin receptor type 2 0.1201 0.1434 0.2455
Toxoplasma gondii heat shock protein 90, putative 0.0143 0.0142 0.1151
Trypanosoma cruzi AMP deaminase 2, putative 0.0029 0.0002 0.0015
Trypanosoma brucei heat shock protein, putative 0.0143 0.0142 0.1151
Schistosoma mansoni peptide (allatostatin/somatostatin)-like receptor 0.1201 0.1434 0.2617
Schistosoma mansoni hypothetical protein 0.0041 0.0017 0.0032
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Plasmodium falciparum 14-3-3 protein, putative 0.0029 0.0002 0.0014
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Echinococcus granulosus dro:myosuppressin receptor 0.1201 0.1434 0.2455
Plasmodium falciparum cysteine repeat modular protein 2 0.0041 0.0017 0.014
Echinococcus multilocularis neuropeptide receptor 0.4514 0.5479 0.9382
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Onchocerca volvulus 0.1201 0.1434 0.5687
Schistosoma mansoni hypothetical protein 0.0029 0.0002 0.0003
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1201 0.1434 0.2617
Leishmania major hypothetical protein, conserved 0.0029 0.0002 0.0015
Loa Loa (eye worm) follicle stimulating hormone receptor 0.213 0.2567 0.7152
Echinococcus multilocularis fmrfamide receptor 0.1201 0.1434 0.2455
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1201 0.1434 0.2617
Leishmania major AMP deaminase, putative,amp deaminase-like protein 0.0029 0.0002 0.0015
Brugia malayi Dopamine receptor protein 2 0.1201 0.1434 0.1434
Trypanosoma brucei heat shock protein, putative 0.0143 0.0142 0.1151
Plasmodium falciparum 14-3-3 protein 0.0035 0.0009 0.0075
Mycobacterium ulcerans 3-dehydroquinate dehydratase 0.2428 0.2932 1
Echinococcus granulosus hypothetical protein 0.1201 0.1434 0.2455
Schistosoma mansoni hypothetical protein 0.2017 0.243 0.4436
Trypanosoma cruzi heat shock protein 90, putative 0.0116 0.0108 0.0881
Echinococcus granulosus heat shock protein heat shock protein 90 alpha 0.013 0.0125 0.0214
Trypanosoma cruzi oligopeptidase B-like protein, putative 0.0056 0.0035 0.0282
Schistosoma mansoni tubulin subunit beta 0.1035 0.123 0.2246
Entamoeba histolytica AMP deaminase, putative 0.0029 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Plasmodium falciparum thioredoxin reductase 0.0062 0.0043 0.035
Leishmania major beta tubulin 0.1035 0.123 1
Onchocerca volvulus 0.1201 0.1434 0.5687
Echinococcus granulosus g-protein coupled receptor 0.1201 0.1434 0.2455
Echinococcus granulosus tm gpcr rhodopsin 0.4809 0.584 1
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0176 0.1428
Schistosoma mansoni biogenic amine receptor 0.1201 0.1434 0.2617
Echinococcus granulosus Tubulin beta 2C chain 0.1035 0.123 0.2107
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Brugia malayi G-protein coupled receptor 0.1201 0.1434 0.1434
Leishmania major beta tubulin 0.1035 0.123 1
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Echinococcus multilocularis thyrotropin releasing hormone receptor 0.1201 0.1434 0.2455
Trypanosoma brucei beta tubulin 0.1035 0.123 1
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Trichomonas vaginalis tubulin epsilon chain, putative 0.1035 0.123 1
Plasmodium vivax cysteine repeat modular protein 3, putative 0.0041 0.0017 0.014
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Echinococcus granulosus Tubulin beta 2C chain 0.1035 0.123 0.2107
Onchocerca volvulus 0.0041 0.0017 0.0069
Echinococcus granulosus pyroglutamylated rfamide peptide receptor 0.1201 0.1434 0.2455
Echinococcus granulosus rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Giardia lamblia Hypothetical protein 0.0041 0.0017 0.0066
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Leishmania major prolyl oligopeptidase, putative,serine peptidase clan SC, family S9A, putative 0.014 0.0138 0.1118
Brugia malayi heat shock protein 90 0.0143 0.0142 0.0142
Schistosoma mansoni cathepsin D (A01 family) 0.0292 0.0324 0.0591
Echinococcus multilocularis beta catenin 0.0187 0.0195 0.0334
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Echinococcus granulosus rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Trypanosoma brucei 14-3-3 protein 2 0.0035 0.0009 0.0075
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Echinococcus granulosus neuropeptide s receptor 0.1201 0.1434 0.2455
Echinococcus granulosus 3'partial|membrane associated guanylate kinase ww and pdz 0.0051 0.0029 0.0049
Brugia malayi prolyl oligopeptidase family protein 0.014 0.0138 0.0138
Loa Loa (eye worm) melatonin receptor type 1A 0.1201 0.1434 0.3994
Echinococcus multilocularis growth hormone secretagogue receptor type 1 0.1201 0.1434 0.2455
Trypanosoma brucei tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0048 0.0392
Echinococcus multilocularis 14-3-3 protein 0.0035 0.0009 0.0016
Echinococcus granulosus sex peptide receptor 0.1201 0.1434 0.2455
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Echinococcus multilocularis serotonin receptor 0.1201 0.1434 0.2455
Mycobacterium leprae PROBABLE CHAPERONE PROTEIN HTPG (HEAT SHOCK PROTEIN) (HSP90 FAMILY PROTEIN) (HIGH TEMPERATURE PROTEIN G) 0.013 0.0125 0.0312
Trypanosoma cruzi heat shock protein 85, putative 0.013 0.0125 0.1017
Echinococcus granulosus beta catenin 0.0187 0.0195 0.0334
Loa Loa (eye worm) 5-hydroxytryptamine 2C receptor 0.1201 0.1434 0.3994
Loa Loa (eye worm) neuropeptide F receptor 0.1201 0.1434 0.3994
Echinococcus multilocularis neuropeptide FF receptor 2 0.1201 0.1434 0.2455
Echinococcus multilocularis tubulin, beta 4A class IVa 0.1035 0.123 0.2107
Giardia lamblia Heat shock protein HSP 90-alpha 0.0143 0.0142 0.1084
Giardia lamblia Beta tubulin 0.1035 0.123 1
Brugia malayi hypothetical protein 0.1201 0.1434 0.1434
Onchocerca volvulus 0.1201 0.1434 0.5687
Brugia malayi 14-3-3-like protein 2 0.0035 0.0009 0.0009
Brugia malayi latrophilin 2 splice variant baaae 0.2017 0.243 0.243
Echinococcus granulosus tachykinin peptides receptor 99D 0.1201 0.1434 0.2455
Schistosoma mansoni hypothetical protein 0.0035 0.0009 0.0017
Plasmodium vivax adenosine deaminase, putative 0.0088 0.0074 0.0604
Echinococcus granulosus SWI:SNF matrix associated 0.0042 0.0018 0.0031
Leishmania major beta tubulin 0.1035 0.123 1
Loa Loa (eye worm) angiotensin-converting enzyme family protein 0.016 0.0162 0.045
Brugia malayi G-protein coupled receptor 0.1201 0.1434 0.1434
Mycobacterium ulcerans adenosine deaminase 0.0088 0.0074 0.0137
Trichomonas vaginalis 14-3-3 protein, putative 0.0029 0.0002 0.0014
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0035 0.0009 0.0075
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0176 0.1428
Echinococcus granulosus GPCR family 2 0.095 0.1127 0.1929
Schistosoma mansoni hypothetical protein 0.0029 0.0002 0.0003
Toxoplasma gondii thioredoxin reductase 0.0062 0.0043 0.035
Schistosoma mansoni ephrin receptor 0.0175 0.0181 0.033
Leishmania major AMP deaminase, putative 0.0029 0.0002 0.0015
Plasmodium falciparum adenosine deaminase 0.0088 0.0074 0.0604
Plasmodium vivax adenosine/AMP deaminase, putative 0.0029 0.0002 0.0015
Leishmania major trypanothione reductase 0.0062 0.0043 0.035
Echinococcus multilocularis transcription factor Dp 1 0.0039 0.0014 0.0024
Schistosoma mansoni hypothetical protein 0.095 0.1127 0.2056
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Schistosoma mansoni peptide (allatostatin)-like receptor 0.2091 0.2521 0.4601
Loa Loa (eye worm) glutaminase 0.0294 0.0326 0.0907
Trypanosoma cruzi oligopeptidase b 0.0056 0.0035 0.0282
Echinococcus granulosus transcription factor Dp 1 0.0039 0.0014 0.0024
Schistosoma mansoni biogenic amine (octopamine/dopamine) receptor 0.1201 0.1434 0.2617
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0285 0.2318
Brugia malayi neuropeptide F receptor 0.1201 0.1434 0.1434
Onchocerca volvulus 0.1201 0.1434 0.5687
Schistosoma mansoni biogenic amine (dopamine) receptor 0.1201 0.1434 0.2617
Treponema pallidum heat shock protein 90 0.013 0.0125 1
Echinococcus multilocularis tm gpcr rhodopsin gpcr rhodopsin superfamily 0.4809 0.584 1
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Trypanosoma brucei heat shock protein 90, putative 0.0143 0.0142 0.1151
Trypanosoma cruzi AMP deaminase, putative 0.0029 0.0002 0.0015
Loa Loa (eye worm) glutaminase 2 0.0294 0.0326 0.0907
Trypanosoma brucei heat shock protein, putative 0.0143 0.0142 0.1151
Loa Loa (eye worm) hypothetical protein 0.0088 0.0075 0.0208
Schistosoma mansoni hypothetical protein 0.0042 0.0018 0.0033
Plasmodium falciparum cysteine repeat modular protein 1 0.0071 0.0053 0.0434
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0176 0.1428
Loa Loa (eye worm) hypothetical protein 0.0041 0.0017 0.0048
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Echinococcus multilocularis neuropeptide s receptor 0.1201 0.1434 0.2455
Schistosoma mansoni amine GPCR 0.1201 0.1434 0.2617
Trichomonas vaginalis adenosine deaminase, putative 0.0088 0.0074 0.0604
Loa Loa (eye worm) tubulin beta chain 0.1035 0.123 0.3428
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Schistosoma mansoni adenosine deaminase-related 0.0088 0.0074 0.0136
Trypanosoma cruzi Heat shock protein 83, putative 0.0143 0.0142 0.1151
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Schistosoma mansoni tubulin subunit beta 0.1035 0.123 0.2246
Toxoplasma gondii 14-3-3 protein 0.0035 0.0009 0.0075
Schistosoma mansoni hypothetical protein 0.1201 0.1434 0.2617
Trypanosoma cruzi AMP deaminase, putative 0.0029 0.0002 0.0015
Echinococcus granulosus 7tm_1 domain containing protein 0.1201 0.1434 0.2455
Brugia malayi Kringle domain containing protein 0.003 0.0003 0.0003
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0051 0.0029 0.0052
Echinococcus multilocularis G protein coupled 5 hydroxytryptamine receptor 0.1201 0.1434 0.2455
Echinococcus granulosus serotonin receptor 0.1201 0.1434 0.2455
Toxoplasma gondii SWIB/MDM2 domain-containing protein 0.0042 0.0018 0.0148
Echinococcus multilocularis 7TM GPCR, rhodopsin 0.1201 0.1434 0.2455
Echinococcus granulosus rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Loa Loa (eye worm) hypothetical protein 0.0059 0.0039 0.0109
Schistosoma mansoni hypothetical protein 0.0029 0.0002 0.0003
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.1201 0.1434 0.2455
Echinococcus granulosus tubulin beta 1 chain 0.1035 0.123 0.2107
Echinococcus multilocularis 14-3-3 protein beta:alpha 0.0035 0.0009 0.0016
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Trypanosoma cruzi heat shock protein 85, putative 0.0143 0.0142 0.1151
Trypanosoma brucei beta tubulin 0.1035 0.123 1
Onchocerca volvulus 0.1201 0.1434 0.5687
Entamoeba histolytica heat shock protein 90, putative 0.0143 0.0142 0.1151
Onchocerca volvulus 0.0041 0.0017 0.0069
Brugia malayi Tyrosyl-DNA phosphodiesterase family protein 0.0067 0.0048 0.0048
Loa Loa (eye worm) hypothetical protein 0.2967 0.359 1
Loa Loa (eye worm) endoplasmin 0.0143 0.0142 0.0394
Leishmania major calcium channel protein, putative,ion transporter, putative 0.0189 0.0198 0.1606
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Loa Loa (eye worm) runx1 0.006 0.004 0.0111
Brugia malayi larval opioid receptor 0.1201 0.1434 0.1434
Mycobacterium ulcerans glutaminase 0.0294 0.0326 0.1004
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1201 0.1434 0.2617
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Loa Loa (eye worm) hypothetical protein 0.0041 0.0017 0.0048
Brugia malayi Melatonin receptor type 1A 0.1201 0.1434 0.1434
Plasmodium falciparum plasmepsin II 0.0099 0.0088 0.0713
Entamoeba histolytica 14-3-3 protein 2 0.0035 0.0009 0.0075
Schistosoma mansoni biogenic amine (5HT) receptor 0.1201 0.1434 0.2617
Echinococcus multilocularis Upstream activation factor subunit UAF30 0.0042 0.0018 0.0031
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Brugia malayi GCC2 and GCC3 family protein 0.0041 0.0017 0.0017
Onchocerca volvulus 0.2091 0.2521 1
Echinococcus multilocularis peptide (allatostatin:somatostatin) 0.1201 0.1434 0.2455
Trypanosoma cruzi adenosine monophosphate deaminase, putative 0.0029 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.0059 0.0039 0.0109
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0176 0.1428
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Entamoeba histolytica hypothetical protein, conserved 0.0041 0.0017 0.014
Schistosoma mansoni neuropeptide receptor 0.1201 0.1434 0.2617
Toxoplasma gondii AMP deaminase 0.0029 0.0002 0.0015
Echinococcus multilocularis GPCR, family 2 0.095 0.1127 0.1929
Brugia malayi Endoplasmin precursor 0.0143 0.0142 0.0142
Echinococcus granulosus allatostatin A receptor 0.2091 0.2521 0.4317
Schistosoma mansoni tyrosyl-DNA phosphodiesterase 0.0067 0.0048 0.0088
Mycobacterium leprae 3-dehydroquinate dehydratase AroD (AroQ) (3-dehydroquinase) (Type II DHQase) 0.2428 0.2932 1
Onchocerca volvulus 0.1201 0.1434 0.5687
Echinococcus multilocularis Protein lozenge 0.006 0.004 0.0068
Trypanosoma brucei RNA helicase, putative 0.054 0.0626 0.509
Echinococcus granulosus adenosine deaminase 0.0088 0.0074 0.0127
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Plasmodium vivax glutathione reductase, putative 0.0062 0.0043 0.035
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Loa Loa (eye worm) hypothetical protein 0.003 0.0003 0.0008
Brugia malayi hypothetical protein 0.1201 0.1434 0.1434
Loa Loa (eye worm) hypothetical protein 0.0041 0.0017 0.0048
Brugia malayi G-protein-linked acetylcholine receptor protein 2, putative 0.1201 0.1434 0.1434
Trichomonas vaginalis glucosylceramidase, putative 0.0171 0.0176 0.1428
Toxoplasma gondii GCC2 and GCC3 domain-containing protein 0.0041 0.0017 0.014
Brugia malayi Protein kinase domain containing protein 0.0032 0.0005 0.0005
Brugia malayi calcium-independent alpha-latrotoxin receptor 2, putative 0.095 0.1127 0.1127
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0005
Schistosoma mansoni tubulin subunit beta 0.1035 0.123 0.2246
Trypanosoma cruzi AMP deaminase, putative 0.0029 0.0002 0.0015
Brugia malayi neuropeptide F receptor 0.1201 0.1434 0.1434
Leishmania major beta tubulin 0.1035 0.123 1
Echinococcus granulosus 14-3-3 protein epsilon 0.0035 0.0009 0.0016
Schistosoma mansoni hypothetical protein 0.095 0.1127 0.2056
Schistosoma mansoni serine-type protease inhibitor 0.0428 0.049 0.0894
Loa Loa (eye worm) aspartic protease BmAsp-2 0.0099 0.0088 0.0245
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Giardia lamblia Beta tubulin 0.1035 0.123 1
Leishmania major beta tubulin 0.1035 0.123 1
Echinococcus multilocularis sodium channel protein 0.0189 0.0198 0.0338
Loa Loa (eye worm) glutathione reductase 0.0062 0.0043 0.012
Onchocerca volvulus 0.0029 0.0002 0.0007
Echinococcus granulosus fmrfamide receptor 0.1201 0.1434 0.2455
Giardia lamblia Heat shock protein HSP 90-alpha 0.013 0.0125 0.0949
Echinococcus multilocularis cathepsin d (lysosomal aspartyl protease) 0.0099 0.0088 0.015
Brugia malayi brahma associated protein 60 kDa 0.0042 0.0018 0.0018
Leishmania major beta tubulin 0.1035 0.123 1
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Loa Loa (eye worm) hypothetical protein 0.0051 0.0029 0.008
Schistosoma mansoni peptide (FMRFamide/neurokinin-3)-like receptor 0.1201 0.1434 0.2617
Echinococcus multilocularis g protein coupled receptor 0.1201 0.1434 0.2455
Leishmania major oligopeptidase B-like protein,serine peptidase, clan SC, family S9A-like protein 0.0056 0.0035 0.0282
Onchocerca volvulus 0.1201 0.1434 0.5687
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0035 0.0009 0.0075
Loa Loa (eye worm) unidentified vitellogenin-linked transcript protein 6 0.1201 0.1434 0.3994
Echinococcus multilocularis tyrosyl DNA phosphodiesterase 1 0.0067 0.0048 0.0082
Loa Loa (eye worm) TYRA-2 protein 0.1201 0.1434 0.3994
Loa Loa (eye worm) O-glycosyl hydrolase family 30 protein 0.0261 0.0285 0.0794
Schistosoma mansoni heat shock protein 0.0143 0.0142 0.0258
Echinococcus multilocularis rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Echinococcus granulosus g protein linked acetylcholine receptor gar 2a 0.1201 0.1434 0.2455
Plasmodium vivax 14-3-3 protein, putative 0.0029 0.0002 0.0014
Echinococcus granulosus neuropeptide receptor 0.1201 0.1434 0.2455
Brugia malayi Adenosine/AMP deaminase family protein 0.0088 0.0074 0.0074
Echinococcus multilocularis Tubulin beta 2C chain 0.1035 0.123 0.2107
Trypanosoma brucei prolyl endopeptidase 0.014 0.0138 0.1118
Schistosoma mansoni hypothetical protein 0.095 0.1127 0.2056
Echinococcus granulosus tissue type plasminogen activator 0.003 0.0003 0.0005
Schistosoma mansoni subfamily A1A unassigned peptidase (A01 family) 0.0099 0.0088 0.016
Plasmodium vivax tubulin beta chain, putative 0.1035 0.123 1
Entamoeba histolytica adenosine deaminase, putative 0.0088 0.0074 0.0604
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Echinococcus granulosus rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Loa Loa (eye worm) TK/ROR protein kinase 0.0032 0.0005 0.0015
Brugia malayi Corticotropin releasing factor receptor 2 precursor, putative 0.2967 0.359 0.359
Brugia malayi Tachykinin-like peptides receptor 99D 0.1201 0.1434 0.1434
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Onchocerca volvulus Glucosylceramidase homolog 0.0171 0.0176 0.0697
Trypanosoma cruzi heat shock protein 90, putative 0.013 0.0125 0.1017
Echinococcus multilocularis tissue type plasminogen activator 0.003 0.0003 0.0005
Trypanosoma cruzi AMP deaminase, putative 0.0029 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Leishmania major oligopeptidase b 0.0056 0.0035 0.0282
Echinococcus granulosus cadherin EGF LAG seven pass G type receptor 0.095 0.1127 0.1929
Plasmodium falciparum 14-3-3 protein 0.0029 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Schistosoma mansoni AMP deaminase 0.0029 0.0002 0.0003
Brugia malayi hypothetical protein 0.0476 0.0548 0.0548
Brugia malayi brahma associated protein 60 kDa 0.0042 0.0018 0.0018
Echinococcus granulosus tubulin beta 4A class IVa 0.1035 0.123 0.2107
Loa Loa (eye worm) latrophilin receptor protein 2 0.095 0.1127 0.3138
Echinococcus granulosus 14-3-3 protein 0.0035 0.0009 0.0016
Echinococcus multilocularis adenosine deaminase 0.0088 0.0074 0.0127
Mycobacterium leprae Probable adenosine deaminase Add (ADENOSINE AMINOHYDROLASE) 0.0088 0.0074 0.0137
Brugia malayi hypothetical protein 0.1201 0.1434 0.1434
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0071 0.0053 0.0091
Mycobacterium tuberculosis Probable adenosine deaminase Add (adenosine aminohydrolase) 0.0088 0.0074 0.0137
Trypanosoma brucei prolyl oligopeptidase, putative 0.0056 0.0035 0.0282
Onchocerca volvulus Cirhin homolog 0.0186 0.0194 0.0768
Echinococcus multilocularis fmrfamide receptor 0.1201 0.1434 0.2455
Schistosoma mansoni brg-1 associated factor 0.0042 0.0018 0.0033
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0002 0.0014
Echinococcus multilocularis neuropeptides capa receptor 0.1201 0.1434 0.2455
Entamoeba histolytica 14-3-3 protein 1 0.0035 0.0009 0.0075
Entamoeba histolytica 14-3-3 protein 3 0.0035 0.0009 0.0075
Chlamydia trachomatis SWIB complex protein 0.0042 0.0018 0.5
Schistosoma mansoni biogenic amine receptor 0.1201 0.1434 0.2617
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0285 0.2318
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Trichomonas vaginalis tubulin, putative 0.1035 0.123 1
Loa Loa (eye worm) hypothetical protein 0.2017 0.243 0.6769
Echinococcus granulosus heat shock protein 90 0.013 0.0125 0.0214
Plasmodium vivax cysteine repeat modular protein 1, putative 0.0071 0.0053 0.0434
Loa Loa (eye worm) HMP-2 protein 0.0187 0.0195 0.0544
Brugia malayi glutathione reductase 0.0062 0.0043 0.0043
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Mycobacterium tuberculosis Probable chaperone protein HtpG (heat shock protein) (HSP90 family protein) (high temperature protein G) 0.013 0.0125 0.0312
Plasmodium falciparum plasmepsin IV 0.0099 0.0088 0.0713
Trypanosoma cruzi prolyl endopeptidase 0.014 0.0138 0.1118
Plasmodium falciparum heat shock protein 90 0.0143 0.0142 0.1151
Echinococcus multilocularis AMP deaminase 2 0.0029 0.0002 0.0003
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Echinococcus granulosus endoplasmin 0.013 0.0125 0.0214
Trypanosoma brucei Heat shock protein 83, putative 0.0143 0.0142 0.1151
Trichomonas vaginalis tubulin beta chain, putative 0.1035 0.123 1
Echinococcus granulosus biogenic amine 5HT receptor 0.1201 0.1434 0.2455
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0035 0.0009 0.0075
Loa Loa (eye worm) hypothetical protein 0.0099 0.0088 0.0245
Schistosoma mansoni biogenic amine (dopamine) receptor 0.1201 0.1434 0.2617
Loa Loa (eye worm) G-protein coupled receptor 0.1201 0.1434 0.3994
Schistosoma mansoni growth hormone secretagogue receptor 0.1201 0.1434 0.2617
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1201 0.1434 0.2617
Schistosoma mansoni cathepsin D (A01 family) 0.0292 0.0324 0.0591
Echinococcus granulosus heat shock protein 90 0.0143 0.0142 0.0242
Toxoplasma gondii 14-3-3 superfamily protein 0.0029 0.0002 0.0014
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.014 0.0138 0.0251
Echinococcus multilocularis rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Echinococcus granulosus 14-3-3 protein beta:alpha 0.0035 0.0009 0.0016
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0035 0.0009 0.0075
Schistosoma mansoni biogenic amine (5HT) receptor 0.1201 0.1434 0.2617
Echinococcus granulosus voltage gated sodium channel Nav1 alpha subunit 0.0189 0.0198 0.0338
Schistosoma mansoni prolyl oligopeptidase (S09 family) 0.014 0.0138 0.0251
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Echinococcus granulosus rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Plasmodium vivax aspartyl proteinase, putative 0.0099 0.0088 0.0713
Schistosoma mansoni hypothetical protein 0.0029 0.0002 0.0003
Echinococcus granulosus endonuclease reverse transcriptase 0.0041 0.0017 0.003
Echinococcus multilocularis G-protein coupled receptor, putative 0.1201 0.1434 0.2455
Schistosoma mansoni adenosine deaminase 0.0088 0.0074 0.0136
Echinococcus granulosus 14-3-3 protein zeta:delta 0.0035 0.0009 0.0016
Plasmodium falciparum endoplasmin, putative 0.0041 0.0017 0.0134
Echinococcus granulosus Tubulin beta 2C chain 0.1035 0.123 0.2107
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Echinococcus granulosus heat shock protein 0.0143 0.0142 0.0242
Trypanosoma cruzi 14-3-3 protein 2, putative 0.0035 0.0009 0.0075
Schistosoma mansoni opsin-like receptor 0.1201 0.1434 0.2617
Schistosoma mansoni beta-catenin 0.0187 0.0195 0.0356
Plasmodium falciparum AMP deaminase, putative 0.0029 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Echinococcus granulosus neuropeptide receptor 0.4514 0.5479 0.9382
Entamoeba histolytica adenosine deaminase, putative 0.0088 0.0074 0.0604
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0285 0.2318
Loa Loa (eye worm) SWIB/MDM2 domain-containing protein 0.0042 0.0018 0.0051
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.0088 0.0074 0.0207
Echinococcus multilocularis SWI:SNF matrix associated 0.0042 0.0018 0.0031
Toxoplasma gondii hypothetical protein 0.0029 0.0002 0.0014
Echinococcus multilocularis pyroglutamylated rfamide peptide receptor 0.1201 0.1434 0.2455
Brugia malayi AKH receptor 0.1201 0.1434 0.1434
Brugia malayi glutaminase DH11.1 0.0294 0.0326 0.0326
Schistosoma mansoni thyrotropin-releasing hormone receptor 0.1201 0.1434 0.2617
Trypanosoma brucei heat shock protein, putative 0.0143 0.0142 0.1151
Schistosoma mansoni hypothetical protein 0.003 0.0003 0.0005
Echinococcus multilocularis heat shock protein 90 0.0143 0.0142 0.0242
Schistosoma mansoni alpha-1 adrenergic receptor 0.1201 0.1434 0.2617
Echinococcus multilocularis g protein coupled receptor 0.1201 0.1434 0.2455
Echinococcus multilocularis g protein linked acetylcholine receptor gar 2a 0.1201 0.1434 0.2455
Echinococcus multilocularis cadherin EGF LAG seven pass G type receptor 0.095 0.1127 0.1929
Trypanosoma brucei AMP deaminase, putative 0.0029 0.0002 0.0015
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Schistosoma mansoni tubulin subunit beta 0.1035 0.123 0.2246
Schistosoma mansoni histamine-responsive GPCR (AAF21638) 0.1201 0.1434 0.2617
Trypanosoma brucei oligopeptidase b 0.0056 0.0035 0.0282
Leishmania major 14-3-3 protein, putative 0.0035 0.0009 0.0075
Echinococcus granulosus tm gpcr rhodopsin 0.1201 0.1434 0.2455
Leishmania major beta tubulin 0.1035 0.123 1
Loa Loa (eye worm) tubulin beta-1 chain 0.1035 0.123 0.3428
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Echinococcus multilocularis Tubulin beta 2C chain 0.1035 0.123 0.2107
Echinococcus granulosus diuretic hormone 44 receptor GPRdih2 0.095 0.1127 0.1929
Schistosoma mansoni amine GPCR 0.1201 0.1434 0.2617
Schistosoma mansoni biogenic amine (dopamine) receptor 0.1201 0.1434 0.2617
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Echinococcus granulosus 7TM GPCR rhodopsin 0.1201 0.1434 0.2455
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Schistosoma mansoni peptide (FMRFamide/somatostatin)-like receptor 0.1201 0.1434 0.2617
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Loa Loa (eye worm) AMP deaminase 0.0029 0.0002 0.0005
Schistosoma mansoni endoplasmin 0.0143 0.0142 0.0258
Schistosoma mansoni hypothetical protein 0.0042 0.0018 0.0033
Brugia malayi beta-tubulin, identical 0.1035 0.123 0.123
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Schistosoma mansoni histamine h1 receptor 0.1201 0.1434 0.2617
Echinococcus granulosus g protein coupled receptor 0.1201 0.1434 0.2455
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Leishmania major beta tubulin 0.1035 0.123 1
Echinococcus multilocularis neuropeptide receptor A26 0.1201 0.1434 0.2455
Echinococcus granulosus G protein coupled receptor 139 0.1201 0.1434 0.2455
Trichomonas vaginalis conserved hypothetical protein 0.0029 0.0002 0.0014
Onchocerca volvulus 0.1201 0.1434 0.5687
Schistosoma mansoni tubulin subunit beta 0.1035 0.123 0.2246
Brugia malayi SWIB/MDM2 domain containing protein 0.0042 0.0018 0.0018
Giardia lamblia Beta tubulin 0.1035 0.123 1
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0187 0.1519
Echinococcus multilocularis dro:myosuppressin receptor 0.1201 0.1434 0.2455
Loa Loa (eye worm) gonadotropin-releasing hormone receptor 2 0.1201 0.1434 0.3994
Plasmodium falciparum conserved protein, unknown function 0.0041 0.0017 0.014
Onchocerca volvulus 0.0042 0.0018 0.0072
Onchocerca volvulus 0.1201 0.1434 0.5687
Trypanosoma brucei AMP deaminase, putative 0.0029 0.0002 0.0015
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Loa Loa (eye worm) hypothetical protein 0.0174 0.0179 0.0498
Trypanosoma cruzi adenosine monophosphate deaminase-like protein, putative 0.0029 0.0002 0.0015
Schistosoma mansoni hypothetical protein 0.0035 0.0009 0.0017
Echinococcus multilocularis allatostatin A receptor 0.2091 0.2521 0.4317
Echinococcus multilocularis endonuclease reverse transcriptase 0.0041 0.0017 0.003
Trypanosoma brucei trypanothione reductase 0.0062 0.0043 0.035
Echinococcus granulosus AMP deaminase 2 0.0029 0.0002 0.0003
Brugia malayi putative neuropeptide receptor 0.1201 0.1434 0.1434
Trichomonas vaginalis glucosylceramidase, putative 0.0261 0.0285 0.2318
Trichomonas vaginalis heat shock protein, putative 0.013 0.0125 0.1017
Schistosoma mansoni heat shock protein 0.0143 0.0142 0.0258
Echinococcus granulosus G protein coupled 5 hydroxytryptamine receptor 0.1201 0.1434 0.2455
Trypanosoma brucei heat shock protein, putative 0.0143 0.0142 0.1151
Schistosoma mansoni hypothetical protein 0.1201 0.1434 0.2617
Schistosoma mansoni tubulin subunit beta 0.1035 0.123 0.2246
Schistosoma mansoni hypothetical protein 0.0029 0.0002 0.0003
Echinococcus multilocularis g-protein coupled receptor 0.1201 0.1434 0.2455
Plasmodium falciparum SWIB/MDM2 domain-containing protein 0.0042 0.0018 0.0148
Toxoplasma gondii prolyl endopeptidase 0.014 0.0138 0.1118
Trypanosoma brucei heat shock protein, putative 0.0143 0.0142 0.1151
Trichomonas vaginalis glucosylceramidase, putative 0.018 0.0187 0.1519
Plasmodium vivax endoplasmin, putative 0.0143 0.0142 0.1151
Echinococcus multilocularis 14-3-3 protein 0.0035 0.0009 0.0016
Plasmodium vivax hypothetical protein, conserved 0.0041 0.0017 0.014
Echinococcus multilocularis neuropeptide Y receptor 0.1201 0.1434 0.2455
Loa Loa (eye worm) hypothetical protein 0.2091 0.2521 0.7022
Entamoeba histolytica tyrosyl-DNA phosphodiesterase, putative 0.0067 0.0048 0.0392
Loa Loa (eye worm) hypothetical protein 0.0029 0.0002 0.0005
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Mycobacterium tuberculosis Probable protease II PtrBa [first part] (oligopeptidase B) 0.0125 0.012 0.0293
Echinococcus granulosus neuropeptide receptor A26 0.1201 0.1434 0.2455
Plasmodium falciparum glutathione reductase 0.0062 0.0043 0.035
Trypanosoma brucei beta tubulin 0.1035 0.123 1
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Trypanosoma brucei adenosine monophosphate deaminase, putative 0.0029 0.0002 0.0015
Trypanosoma cruzi 14-3-3 protein 2, putative 0.0035 0.0009 0.0075
Echinococcus granulosus cathepsin d lysosomal aspartyl protease 0.0099 0.0088 0.015
Schistosoma mansoni membrane associated guanylate kinase inverted related 0.0071 0.0053 0.0097
Leishmania major hypothetical protein, conserved 0.003 0.0003 0.0024
Trypanosoma cruzi heat shock protein 90, putative 0.0143 0.0142 0.1151
Onchocerca volvulus Adenosine deaminase homolog 0.0088 0.0074 0.0295
Echinococcus multilocularis g protein coupled receptor 0.1201 0.1434 0.2455
Echinococcus multilocularis tubulin subunit beta 0.1035 0.123 0.2107
Brugia malayi 14-3-3 protein 0.0029 0.0002 0.0002
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Plasmodium vivax 14-3-3 protein, putative 0.0029 0.0002 0.0014
Trypanosoma brucei heat shock protein, putative 0.0143 0.0142 0.1151
Onchocerca volvulus Neuropeptide F receptor homolog 0.1201 0.1434 0.5687
Echinococcus multilocularis beta tubulin 0.1035 0.123 0.2107
Trichomonas vaginalis Clan AA, family A1, cathepsin D-like aspartic peptidase 0.0099 0.0088 0.0713
Echinococcus multilocularis membrane associated guanylate kinase ww and pdz 0.0051 0.0029 0.0049
Leishmania major AMP deaminase, putative,adenosine monophosphate deaminase-like protein 0.0029 0.0002 0.0015
Trypanosoma cruzi beta tubulin, putative 0.1035 0.123 1
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Echinococcus multilocularis prolyl endopeptidase 0.014 0.0138 0.0236
Schistosoma mansoni hypothetical protein 0.0035 0.0009 0.0017
Leishmania major 14-3-3 protein-like protein 0.0035 0.0009 0.0075
Trichomonas vaginalis tubulin epsilon chain, putative 0.1035 0.123 1
Mycobacterium tuberculosis 3-dehydroquinate dehydratase AroD (AROQ) (3-dehydroquinase) (type II dhqase) 0.2428 0.2932 1
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Schistosoma mansoni biogenic amine receptor 0.1201 0.1434 0.2617
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0035 0.0009 0.0075
Trichomonas vaginalis heat shock protein, putative 0.013 0.0125 0.1017
Trypanosoma brucei heat shock protein 90, putative 0.0143 0.0142 0.1151
Plasmodium vivax hypothetical protein, conserved 0.0042 0.0018 0.0148
Echinococcus multilocularis tubulin beta 1 chain 0.1035 0.123 0.2107
Loa Loa (eye worm) hypothetical protein 0.0059 0.0039 0.0109
Echinococcus granulosus peptide allatostatin:somatostatin 0.1201 0.1434 0.2455
Onchocerca volvulus 0.1201 0.1434 0.5687
Echinococcus granulosus growth hormone secretagogue receptor type 1 0.1201 0.1434 0.2455
Toxoplasma gondii beta-1 tubulin, putative 0.1035 0.123 1
Brugia malayi gonadotropin-releasing hormone receptor 2 0.1201 0.1434 0.1434
Echinococcus multilocularis beta tubulin 0.1035 0.123 0.2107
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Brugia malayi sulfakinin receptor protein 0.1627 0.1954 0.1954
Toxoplasma gondii aspartyl protease ASP1 0.0099 0.0088 0.0713
Toxoplasma gondii beta tubulin 0.1035 0.123 1
Echinococcus multilocularis ephrin type A receptor 4 A 0.0217 0.0232 0.0396
Leishmania major beta tubulin 0.1035 0.123 1
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Brugia malayi Angiotensin-converting enzyme family protein 0.016 0.0162 0.0162
Echinococcus multilocularis serotonin receptor 0.1201 0.1434 0.2455
Echinococcus granulosus thioredoxin glutathione reductase 0.0062 0.0043 0.0074
Brugia malayi 14-3-3-like protein 2 0.0035 0.0009 0.0009
Onchocerca volvulus Dopamine\/Ecdysteroid receptor homolog 0.1201 0.1434 0.5687
Schistosoma mansoni myosin xvIII 0.1201 0.1434 0.2617
Giardia lamblia Grp94/Hsp90 0.013 0.0125 0.0949
Trypanosoma cruzi oligopeptidase b 0.0056 0.0035 0.0282
Brugia malayi ORL1-like opioid receptor 0.1201 0.1434 0.1434
Echinococcus multilocularis neuropeptide Y receptor 0.1201 0.1434 0.2455
Echinococcus granulosus prolyl endopeptidase 0.014 0.0138 0.0236
Schistosoma mansoni glutaminase 0.0294 0.0326 0.0594
Brugia malayi Dopamine receptor protein 1 0.1201 0.1434 0.1434
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Toxoplasma gondii kringle domain-containing protein 0.0071 0.0053 0.0434
Mycobacterium ulcerans heat shock protein 90 0.013 0.0125 0.0312
Leishmania major adenine aminohydrolase 0.0088 0.0074 0.0604
Trypanosoma cruzi 14-3-3 protein 1, putative 0.0035 0.0009 0.0075
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Loa Loa (eye worm) hypothetical protein 0.0476 0.0548 0.1527
Schistosoma mansoni hypothetical protein 0.0042 0.0018 0.0033
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Echinococcus granulosus alpha 1A adrenergic receptor 0.1201 0.1434 0.2455
Plasmodium vivax cysteine repeat modular protein 2, putative 0.0041 0.0017 0.014
Leishmania major beta tubulin 0.1035 0.123 1
Schistosoma mansoni adenoreceptor 0.1201 0.1434 0.2617
Schistosoma mansoni lozenge 0.006 0.004 0.0073
Brugia malayi O-Glycosyl hydrolase family 30 protein 0.0261 0.0285 0.0285
Schistosoma mansoni neuropeptide f receptor 76f 0.1201 0.1434 0.2617
Echinococcus multilocularis rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Echinococcus multilocularis Tubulin beta 2C chain 0.1035 0.123 0.2107
Echinococcus multilocularis heat shock protein 0.0143 0.0142 0.0242
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Trichomonas vaginalis adenosine deaminase, putative 0.0088 0.0074 0.0604
Toxoplasma gondii beta-tubulin, putative 0.1035 0.123 1
Onchocerca volvulus Prolyl endopeptidase homolog 0.014 0.0138 0.0546
Echinococcus granulosus orexin receptor type 2 0.1201 0.1434 0.2455
Loa Loa (eye worm) hypothetical protein 0.0041 0.0017 0.0048
Loa Loa (eye worm) pigment dispersing factor receptor c 0.2967 0.359 1
Echinococcus multilocularis 0.0071 0.0053 0.0091
Loa Loa (eye worm) hypothetical protein 0.095 0.1127 0.3138
Schistosoma mansoni hypothetical protein 0.1201 0.1434 0.2617
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1201 0.1434 0.2617
Echinococcus multilocularis Tubulin beta 2C chain 0.1035 0.123 0.2107
Trypanosoma brucei 14-3-3 protein 1 0.0035 0.0009 0.0075
Schistosoma mansoni neuropeptide F-like receptor 0.1201 0.1434 0.2617
Leishmania major beta tubulin 0.1035 0.123 1
Leishmania major beta tubulin 0.1035 0.123 1
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Brugia malayi Unidentified vitellogenin-linked transcript protein 6, putative 0.1201 0.1434 0.1434
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1201 0.1434 0.2617
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Schistosoma mansoni ancient conserved domain protein 2 (cyclin m2) 0.1201 0.1434 0.2617
Echinococcus multilocularis neuropeptide receptor 0.1201 0.1434 0.2455
Schistosoma mansoni serine-type protease inhibitor 0.0428 0.049 0.0894
Loa Loa (eye worm) tubulin beta-2A chain 0.1035 0.123 0.3428
Entamoeba histolytica hypothetical protein 0.0041 0.0017 0.014
Trichomonas vaginalis grf14, putative 0.0029 0.0002 0.0014
Onchocerca volvulus 0.003 0.0003 0.0012
Brugia malayi adenosine monophosphate deaminase 0.0029 0.0002 0.0002
Brugia malayi G protein-coupled receptor 0.1201 0.1434 0.1434
Onchocerca volvulus 0.0476 0.0548 0.2175
Trypanosoma cruzi serine peptidase, clan SC, family S9A-like protein, putative 0.0056 0.0035 0.0282
Plasmodium falciparum tubulin beta chain 0.1035 0.123 1
Echinococcus granulosus tyrosyl DNA phosphodiesterase 1 0.0067 0.0048 0.0082
Plasmodium vivax thioredoxin reductase, putative 0.0062 0.0043 0.035
Toxoplasma gondii DNA topoisomerase domain-containing protein 0.0042 0.0018 0.0148
Echinococcus granulosus Tubulin beta 2C chain 0.1035 0.123 0.2107
Loa Loa (eye worm) hypothetical protein 0.0059 0.0039 0.0109
Schistosoma mansoni hypothetical protein 0.0035 0.0009 0.0017
Echinococcus multilocularis endoplasmin 0.013 0.0125 0.0214
Echinococcus granulosus membrane associated guanylate kinase, WW and PDZ 0.0051 0.0029 0.0049
Schistosoma mansoni neuropeptide receptor 0.1201 0.1434 0.2617
Brugia malayi Dopamine receptor 0.1201 0.1434 0.1434
Brugia malayi hypothetical protein 0.1201 0.1434 0.1434
Entamoeba histolytica AMP deaminase, putative 0.0029 0.0002 0.0015
Trichomonas vaginalis tubulin alpha chain, putative 0.1035 0.123 1
Echinococcus multilocularis thioredoxin glutathione reductase 0.0062 0.0043 0.0074
Echinococcus granulosus sodium channel protein 0.0189 0.0198 0.0338
Echinococcus multilocularis sex peptide receptor 0.1201 0.1434 0.2455
Echinococcus multilocularis G protein coupled receptor 139 0.4514 0.5479 0.9382
Onchocerca volvulus 0.1201 0.1434 0.5687
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Toxoplasma gondii hypothetical protein 0.0041 0.0017 0.014
Schistosoma mansoni amine GPCR 0.1201 0.1434 0.2617
Plasmodium falciparum plasmepsin VI 0.0099 0.0088 0.0713
Echinococcus multilocularis SWI:SNF matrix associated 0.0042 0.0018 0.0031
Schistosoma mansoni rhodopsin-like orphan GPCR 0.1201 0.1434 0.2617
Plasmodium falciparum cysteine repeat modular protein 3 0.0041 0.0017 0.014
Echinococcus multilocularis somatostatin receptor 0.1201 0.1434 0.2455
Echinococcus multilocularis alpha 1A adrenergic receptor 0.1201 0.1434 0.2455
Echinococcus multilocularis biogenic amine (5HT) receptor 0.1201 0.1434 0.2455
Loa Loa (eye worm) hypothetical protein 0.014 0.0138 0.0383
Leishmania major beta tubulin 0.1035 0.123 1
Schistosoma mansoni hypothetical protein 0.095 0.1127 0.2056
Schistosoma mansoni hypothetical protein 0.054 0.0626 0.1143
Echinococcus multilocularis rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Mycobacterium tuberculosis NADPH-dependent mycothiol reductase Mtr 0.0062 0.0043 0.0029
Leishmania major tyrosyl-DNA phosphodiesterase 1 0.0067 0.0048 0.0392
Trypanosoma cruzi 14-3-3 protein 1, putative 0.0035 0.0009 0.0075
Brugia malayi hypothetical protein 0.1201 0.1434 0.1434
Schistosoma mansoni opsin-like receptor 0.1201 0.1434 0.2617
Brugia malayi GCC2 and GCC3 family protein 0.0041 0.0017 0.0017
Echinococcus granulosus somatostatin receptor 0.1201 0.1434 0.2455
Brugia malayi Latrophilin receptor protein 2 0.095 0.1127 0.1127
Trypanosoma cruzi trypanothione reductase, putative 0.0062 0.0043 0.035
Echinococcus multilocularis neuropeptides capa receptor 0.1201 0.1434 0.2455
Loa Loa (eye worm) hypothetical protein 0.1627 0.1954 0.5443
Leishmania major heat shock protein 83-1 0.0143 0.0142 0.1151
Brugia malayi hypothetical protein 0.1201 0.1434 0.1434
Echinococcus granulosus rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Toxoplasma gondii heat shock protein HSP90 0.0143 0.0142 0.1151
Echinococcus granulosus g protein coupled receptor 0.1201 0.1434 0.2455
Loa Loa (eye worm) hypothetical protein 0.1201 0.1434 0.3994
Loa Loa (eye worm) neuropeptide F receptor 0.1201 0.1434 0.3994
Loa Loa (eye worm) brahma associated protein 0.0042 0.0018 0.0051
Loa Loa (eye worm) tubulin beta-4 chain 0.1035 0.123 0.3428
Trypanosoma cruzi tyrosyl-DNA Phosphodiesterase (Tdp1), putative 0.0067 0.0048 0.0392
Trypanosoma cruzi AMP deaminase, putative 0.0029 0.0002 0.0015
Echinococcus granulosus membrane associated guanylate kinase ww and pdz 0.0051 0.0029 0.0049
Echinococcus multilocularis membrane associated guanylate kinase, WW and PDZ 0.0051 0.0029 0.0049
Echinococcus granulosus Tubulin beta 2C chain 0.1035 0.123 0.2107
Chlamydia trachomatis DNA topoisomerase I 0.0042 0.0018 0.5
Echinococcus granulosus rhodopsin orphan GPCR 0.1201 0.1434 0.2455
Onchocerca volvulus AMP deaminase 2 homolog 0.0029 0.0002 0.0007
Trypanosoma brucei AMP deaminase, putative 0.0029 0.0002 0.0015
Schistosoma mansoni neuropeptide F-like receptor 0.1201 0.1434 0.2617
Trypanosoma cruzi heat shock protein 85, putative 0.0143 0.0142 0.1151
Echinococcus granulosus neuropeptide Y receptor 0.1201 0.1434 0.2455
Plasmodium vivax SWIB/MDM2 domain-containing protein, putative 0.0042 0.0018 0.0148
Echinococcus multilocularis 14-3-3 protein epsilon 0.0035 0.0009 0.0016
Brugia malayi PDZ domain containing protein 0.0052 0.003 0.003
Entamoeba histolytica tubulin family protein 0.1035 0.123 1
Loa Loa (eye worm) hypothetical protein 0.0476 0.0548 0.1527
Brugia malayi Dopamine receptor protein 1, putative (partial) 0.1201 0.1434 0.1434
Loa Loa (eye worm) TK/EPH protein kinase 0.0223 0.0239 0.0666
Trypanosoma brucei beta tubulin 0.1035 0.123 1
Echinococcus granulosus neuropeptide Y receptor 0.1201 0.1434 0.2455
Brugia malayi hypothetical protein 0.1201 0.1434 0.1434
Echinococcus granulosus beta tubulin 0.1035 0.123 0.2107
Trichomonas vaginalis 14-3-3 protein sigma, gamma, zeta, beta/alpha, putative 0.0029 0.0002 0.0014
Brugia malayi GCC2 and GCC3 family protein 0.0041 0.0017 0.0017
Loa Loa (eye worm) BEN-1 protein 0.1035 0.123 0.3428

Activities

No activities found for this compound.

Phenotypes

Whole-cell/tissue/organism interactions

We have no records of whole-cell/tissue assays done with this compound What does this mean?

Many chemical entities in TDR Targets come from high-throughput screenings with whole cells or tissue samples, and not all assayed compounds have been tested against a single a single target protein, probably because they get ruled out during screening process. Even if these compounds may have not been of interest in the original screening, they may come as interesting leads for other screening assays. Furthermore, we may be able to propose drug-target associations using chemical similarities and network patterns.

Annotated phenotypes:

We have no manually annotated phenotypes for this drug. What does this mean? / Care to help?
In TDR Targets, information about phenotypes that are caused by drugs, or by genetic manipulation of cells (e.g. gene knockouts or knockdowns) is manually curated from the literature. These descriptions help to describe the potential of the target for drug development. If no information is available for this gene or if the information is incomplete, this may mean that i) the papers containing this information either appeared after the curation effort for this organism was carried out or they were inadvertently missed by curators; or that ii) the curation effort for this organism has not yet started.
 
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External resources for this compound

Bibliographic References

No literature references available for this target.

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